CmaCh04G019140 (gene) Cucurbita maxima (Rimu) | Cucurbit Genomics Database (CuGenDB)

Overview


Name	CmaCh04G019140
Type	gene
Organism	Cucurbita maxima (Cucurbita maxima (Rimu))
Description	Calcium-binding EF-hand family protein, putative
Location	Cma_Chr04 : 10177971 .. 10178402 (-)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSexon

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGCTAAGTATGAAGCAAGTGAGATGATCAAGAAGTATCCTAGAAATGGTGATGATGTTCAACTAAAATCTTTCGGTGGCATTACTCGAGATTCAACTCAAGTCAACAATCAAGGCAAGATATCGGAAATCCTAAAAGATAACAAGAATGTTGGGCTCAAGCTTAGTTCAAATACTCACCCAAAGACATCTAAGTTGCAATTTAGTCGAGAACAGATGAAGGAGATCTTTAGATATCATGATAGCGACAAGGATGGTTTTCTCAATATAAGAGAGCTAACAAAAGCTTTTGCTTTTCTAGGCTCAATTATTCCATTTGAGAAAGCTTCCTATGGCATGTCATATGCGGATGCAAATAAAGATGGCCTTATCGGCGAGGCTGAACTTGACAAACTCATTGATTATGCCCAGAAATTTGTGAAGAAGAAATGA

mRNA sequence

ATGGCTAAGTATGAAGCAAGTGAGATGATCAAGAAGTATCCTAGAAATGGTGATGATGTTCAACTAAAATCTTTCGGTGGCATTACTCGAGATTCAACTCAAGTCAACAATCAAGGCAAGATATCGGAAATCCTAAAAGATAACAAGAATGTTGGGCTCAAGCTTAGTTCAAATACTCACCCAAAGACATCTAAGTTGCAATTTAGTCGAGAACAGATGAAGGAGATCTTTAGATATCATGATAGCGACAAGGATGGTTTTCTCAATATAAGAGAGCTAACAAAAGCTTTTGCTTTTCTAGGCTCAATTATTCCATTTGAGAAAGCTTCCTATGGCATGTCATATGCGGATGCAAATAAAGATGGCCTTATCGGCGAGGCTGAACTTGACAAACTCATTGATTATGCCCAGAAATTTGTGAAGAAGAAATGA

Coding sequence (CDS)

ATGGCTAAGTATGAAGCAAGTGAGATGATCAAGAAGTATCCTAGAAATGGTGATGATGTTCAACTAAAATCTTTCGGTGGCATTACTCGAGATTCAACTCAAGTCAACAATCAAGGCAAGATATCGGAAATCCTAAAAGATAACAAGAATGTTGGGCTCAAGCTTAGTTCAAATACTCACCCAAAGACATCTAAGTTGCAATTTAGTCGAGAACAGATGAAGGAGATCTTTAGATATCATGATAGCGACAAGGATGGTTTTCTCAATATAAGAGAGCTAACAAAAGCTTTTGCTTTTCTAGGCTCAATTATTCCATTTGAGAAAGCTTCCTATGGCATGTCATATGCGGATGCAAATAAAGATGGCCTTATCGGCGAGGCTGAACTTGACAAACTCATTGATTATGCCCAGAAATTTGTGAAGAAGAAATGA

Protein sequence

MAKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNNQGKISEILKDNKNVGLKLSSNTHPKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFLGSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK

Homology

[Close]

BLAST of CmaCh04G019140 vs. TrEMBL
Match: A0A0A0KLF3_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_5G067670 PE=4 SV=1)

HSP 1 Score: 165.6 bits (418), Expect = 4.4e-38
Identity = 92/163 (56.44%), Postives = 112/163 (68.71%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVN-NQGKISEILKDNKNVGLKLSSNTH 61
           AKYEAS+++KKY +NG+ V L +F    R STQ+N N+   ++ LK N +V  KLSSN  
Sbjct: 38  AKYEASKLMKKYEQNGEGVILSAFNDNARGSTQINTNREMATKKLKPNDDVAHKLSSNAQ 97

Query: 62  --------------------PKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFL 121
                                K S +QFSREQ+KEIF+Y+DSD+DGFLNIRE+TKAFA L
Sbjct: 98  LKSNNQIRGKAQVPIKRVYDTKASNMQFSREQIKEIFQYYDSDRDGFLNIREVTKAFALL 157

Query: 122 GSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           GSI PF KA +GM YAD NKDGLIGE ELDKLI+YA KF+KKK
Sbjct: 158 GSIFPFNKAYHGMVYADTNKDGLIGEDELDKLINYANKFMKKK 200

[Close]

BLAST of CmaCh04G019140 vs. TrEMBL
Match: A0A0A0KMQ1_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_5G067410 PE=4 SV=1)

HSP 1 Score: 159.5 bits (402), Expect = 3.1e-36
Identity = 87/163 (53.37%), Postives = 109/163 (66.87%), Query Frame = 1


Query: 1   MAKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNNQGKISEILKDNKNVGLKLSSNTH 60
           MA YEAS +IK+Y +NGD V++K+F  + R STQ+ N+  + +ILK +  V  KL S  H
Sbjct: 10  MAMYEASMLIKQYEKNGDAVKVKAFDDV-RSSTQIGNRESVLKILKPSDGVAHKLRSEAH 69

Query: 61  --------------------PKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFL 120
                                K+S +  SRE++KEIF+YHD++ DGFLN  ELTKAFAFL
Sbjct: 70  IQPTQRTGGKGKKSITRVLDRKSSNMSLSRERIKEIFQYHDNNNDGFLNRMELTKAFAFL 129

Query: 121 GSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           GS+ PF KA YGM YADAN+DGLI EAELDKLIDYA K +KKK
Sbjct: 130 GSMFPFYKACYGMVYADANEDGLISEAELDKLIDYASKIIKKK 171

[Close]

BLAST of CmaCh04G019140 vs. TrEMBL
Match: A0A0A0LRC8_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_2G359950 PE=4 SV=1)

HSP 1 Score: 157.1 bits (396), Expect = 1.6e-35
Identity = 89/162 (54.94%), Postives = 112/162 (69.14%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDV----QLKSFGGITRDSTQVNNQGKISE--ILKDNKNVGLKL 61
           AK EA+E+IKKY RNGD V    +L+SF    R STQ+NN   +S   + K N+N+  K+
Sbjct: 10  AKNEANELIKKYDRNGDGVLTKEELQSFLRDARGSTQLNNIRNVSSSTVPKTNENLAQKV 69

Query: 62  SSNT--------------HPKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFLG 121
           SSNT                K S +  SREQ+KEIF+YHDS+KDGFL+IRELTKAF+ +G
Sbjct: 70  SSNTCITPKKQLLDKAQGSSKQSNVPLSREQIKEIFKYHDSNKDGFLSIRELTKAFSSMG 129

Query: 122 SIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           SI+PF KA Y M+YAD ++DGL+ EAELDKLIDYA K +KKK
Sbjct: 130 SIVPFCKARYAMAYADVDEDGLVSEAELDKLIDYAHKIIKKK 171

[Close]

BLAST of CmaCh04G019140 vs. TrEMBL
Match: A0A0A0KIY4_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_5G068170 PE=4 SV=1)

HSP 1 Score: 150.6 bits (379), Expect = 1.5e-33
Identity = 85/166 (51.20%), Postives = 109/166 (65.66%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNN-QGKISEIL--KDNKNVGLKLSSN 61
           AKYEAS+++KK+  N + V LK+F GI   ST++NN Q   +EI+    N  V   L+SN
Sbjct: 11  AKYEASKLMKKHENNDEGVPLKAFNGIPPASTKINNKQAMATEIILKPSNHPVAHYLTSN 70

Query: 62  THP---------------------KTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAF 121
            +                      K S +QFSREQ+KEIF+YHDSD DGFLN+RE+TKAF
Sbjct: 71  AYMIPSKQLGAGKAQVTTTSVLDIKASNMQFSREQIKEIFQYHDSDNDGFLNLREVTKAF 130

Query: 122 AFLGSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           AFLG+I+P  KA +GM YADANKDGLI + EL+KL+DYA KF  K+
Sbjct: 131 AFLGTILPLYKAYHGMVYADANKDGLISKDELEKLVDYAYKFFNKR 176

[Close]

BLAST of CmaCh04G019140 vs. TrEMBL
Match: A0A0A0LKX1_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_2G359940 PE=4 SV=1)

HSP 1 Score: 110.5 bits (275), Expect = 1.7e-21
Identity = 54/83 (65.06%), Postives = 62/83 (74.70%), Query Frame = 1


Query: 61  PKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFLGSIIPFEKASYGMSYADANK 120
           P  SK  FSRE+MKEIFR HD D DG+L+I EL KA  FLG  IPF KA YGM+Y D N 
Sbjct: 4   PGVSKFNFSREEMKEIFREHDIDGDGYLSISELIKAMGFLGHSIPFYKAHYGMAYCDENG 63

Query: 121 DGLIGEAELDKLIDYAQKFVKKK 144
           DGLI E ELDKLIDYA++F K++
Sbjct: 64  DGLISEDELDKLIDYAERFQKRR 86

[Close]

BLAST of CmaCh04G019140 vs. NCBI nr
Match: gi|700194512|gb|KGN49689.1| (hypothetical protein Csa_5G067670 [Cucumis sativus])

HSP 1 Score: 165.6 bits (418), Expect = 6.3e-38
Identity = 92/163 (56.44%), Postives = 112/163 (68.71%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVN-NQGKISEILKDNKNVGLKLSSNTH 61
           AKYEAS+++KKY +NG+ V L +F    R STQ+N N+   ++ LK N +V  KLSSN  
Sbjct: 38  AKYEASKLMKKYEQNGEGVILSAFNDNARGSTQINTNREMATKKLKPNDDVAHKLSSNAQ 97

Query: 62  --------------------PKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFL 121
                                K S +QFSREQ+KEIF+Y+DSD+DGFLNIRE+TKAFA L
Sbjct: 98  LKSNNQIRGKAQVPIKRVYDTKASNMQFSREQIKEIFQYYDSDRDGFLNIREVTKAFALL 157

Query: 122 GSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           GSI PF KA +GM YAD NKDGLIGE ELDKLI+YA KF+KKK
Sbjct: 158 GSIFPFNKAYHGMVYADTNKDGLIGEDELDKLINYANKFMKKK 200

[Close]

BLAST of CmaCh04G019140 vs. NCBI nr
Match: gi|700194510|gb|KGN49687.1| (hypothetical protein Csa_5G067410 [Cucumis sativus])

HSP 1 Score: 159.5 bits (402), Expect = 4.5e-36
Identity = 87/163 (53.37%), Postives = 109/163 (66.87%), Query Frame = 1


Query: 1   MAKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNNQGKISEILKDNKNVGLKLSSNTH 60
           MA YEAS +IK+Y +NGD V++K+F  + R STQ+ N+  + +ILK +  V  KL S  H
Sbjct: 10  MAMYEASMLIKQYEKNGDAVKVKAFDDV-RSSTQIGNRESVLKILKPSDGVAHKLRSEAH 69

Query: 61  --------------------PKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFL 120
                                K+S +  SRE++KEIF+YHD++ DGFLN  ELTKAFAFL
Sbjct: 70  IQPTQRTGGKGKKSITRVLDRKSSNMSLSRERIKEIFQYHDNNNDGFLNRMELTKAFAFL 129

Query: 121 GSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           GS+ PF KA YGM YADAN+DGLI EAELDKLIDYA K +KKK
Sbjct: 130 GSMFPFYKACYGMVYADANEDGLISEAELDKLIDYASKIIKKK 171

[Close]

BLAST of CmaCh04G019140 vs. NCBI nr
Match: gi|449470190|ref|XP_004152801.1| (PREDICTED: probable calcium-binding protein CML11 [Cucumis sativus])

HSP 1 Score: 157.1 bits (396), Expect = 2.2e-35
Identity = 89/162 (54.94%), Postives = 112/162 (69.14%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDV----QLKSFGGITRDSTQVNNQGKISE--ILKDNKNVGLKL 61
           AK EA+E+IKKY RNGD V    +L+SF    R STQ+NN   +S   + K N+N+  K+
Sbjct: 10  AKNEANELIKKYDRNGDGVLTKEELQSFLRDARGSTQLNNIRNVSSSTVPKTNENLAQKV 69

Query: 62  SSNT--------------HPKTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFLG 121
           SSNT                K S +  SREQ+KEIF+YHDS+KDGFL+IRELTKAF+ +G
Sbjct: 70  SSNTCITPKKQLLDKAQGSSKQSNVPLSREQIKEIFKYHDSNKDGFLSIRELTKAFSSMG 129

Query: 122 SIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           SI+PF KA Y M+YAD ++DGL+ EAELDKLIDYA K +KKK
Sbjct: 130 SIVPFCKARYAMAYADVDEDGLVSEAELDKLIDYAHKIIKKK 171

[Close]

BLAST of CmaCh04G019140 vs. NCBI nr
Match: gi|700194513|gb|KGN49690.1| (hypothetical protein Csa_5G068170 [Cucumis sativus])

HSP 1 Score: 150.6 bits (379), Expect = 2.1e-33
Identity = 85/166 (51.20%), Postives = 109/166 (65.66%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNN-QGKISEIL--KDNKNVGLKLSSN 61
           AKYEAS+++KK+  N + V LK+F GI   ST++NN Q   +EI+    N  V   L+SN
Sbjct: 11  AKYEASKLMKKHENNDEGVPLKAFNGIPPASTKINNKQAMATEIILKPSNHPVAHYLTSN 70

Query: 62  THP---------------------KTSKLQFSREQMKEIFRYHDSDKDGFLNIRELTKAF 121
            +                      K S +QFSREQ+KEIF+YHDSD DGFLN+RE+TKAF
Sbjct: 71  AYMIPSKQLGAGKAQVTTTSVLDIKASNMQFSREQIKEIFQYHDSDNDGFLNLREVTKAF 130

Query: 122 AFLGSIIPFEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           AFLG+I+P  KA +GM YADANKDGLI + EL+KL+DYA KF  K+
Sbjct: 131 AFLGTILPLYKAYHGMVYADANKDGLISKDELEKLVDYAYKFFNKR 176

[Close]

BLAST of CmaCh04G019140 vs. NCBI nr
Match: gi|659089539|ref|XP_008445564.1| (PREDICTED: probable calcium-binding protein CML11 [Cucumis melo])

HSP 1 Score: 144.1 bits (362), Expect = 1.9e-31
Identity = 84/158 (53.16%), Postives = 103/158 (65.19%), Query Frame = 1


Query: 2   AKYEASEMIKKYPRNGDDVQLKSFGGITRDSTQVNNQGKISE--ILKDNKNVGLKLSSNT 61
           AK EASE+IKKY RNGD V  K          ++ N   +S   I K N+N+  K+SSNT
Sbjct: 10  AKIEASELIKKYDRNGDGVLTKEELQSFLHDARLKNIRFVSSSTIPKTNENLDQKVSSNT 69

Query: 62  HPKTSK--------------LQFSREQMKEIFRYHDSDKDGFLNIRELTKAFAFLGSIIP 121
             K  K              +  SREQ+KEIF+YHDS+KDGFL+IRELTKAF  LGSI+P
Sbjct: 70  RIKPKKQLLDKAQDSLRQSNVPLSREQIKEIFKYHDSNKDGFLSIRELTKAFGSLGSIVP 129

Query: 122 FEKASYGMSYADANKDGLIGEAELDKLIDYAQKFVKKK 144
           F KA + M+YAD ++DGLI EAEL KLIDYA+K +KKK
Sbjct: 130 FAKARHAMAYADVDEDGLISEAELHKLIDYAEKIIKKK 167

The following BLAST results are available for this feature:

BLAST of CmaCh04G019140 vs. Swiss-Prot


Match Name	E-value	Identity	Description

BLAST of CmaCh04G019140 vs. TrEMBL


Match Name	E-value	Identity	Description
A0A0A0KLF3_CUCSA	4.4e-38	56.44	Uncharacterized protein OS=Cucumis sativus GN=Csa_5G067670 PE=4 SV=1	[more]
A0A0A0KMQ1_CUCSA	3.1e-36	53.37	Uncharacterized protein OS=Cucumis sativus GN=Csa_5G067410 PE=4 SV=1	[more]
A0A0A0LRC8_CUCSA	1.6e-35	54.94	Uncharacterized protein OS=Cucumis sativus GN=Csa_2G359950 PE=4 SV=1	[more]
A0A0A0KIY4_CUCSA	1.5e-33	51.20	Uncharacterized protein OS=Cucumis sativus GN=Csa_5G068170 PE=4 SV=1	[more]
A0A0A0LKX1_CUCSA	1.7e-21	65.06	Uncharacterized protein OS=Cucumis sativus GN=Csa_2G359940 PE=4 SV=1	[more]

BLAST of CmaCh04G019140 vs. TAIR10


Match Name	E-value	Identity	Description

BLAST of CmaCh04G019140 vs. NCBI nr


Match Name	E-value	Identity	Description
gi\|700194512\|gb\|KGN49689.1\|	6.3e-38	56.44	hypothetical protein Csa_5G067670 [Cucumis sativus]	[more]
gi\|700194510\|gb\|KGN49687.1\|	4.5e-36	53.37	hypothetical protein Csa_5G067410 [Cucumis sativus]	[more]
gi\|449470190\|ref\|XP_004152801.1\|	2.2e-35	54.94	PREDICTED: probable calcium-binding protein CML11 [Cucumis sativus]	[more]
gi\|700194513\|gb\|KGN49690.1\|	2.1e-33	51.20	hypothetical protein Csa_5G068170 [Cucumis sativus]	[more]
gi\|659089539\|ref\|XP_008445564.1\|	1.9e-31	53.16	PREDICTED: probable calcium-binding protein CML11 [Cucumis melo]	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **INTERPRO**
Term	Definition
IPR002048	EF_hand_dom
IPR011992	EF-hand-dom_pair
IPR018247	EF_Hand_1_Ca_BS

Vocabulary: **Molecular Function**
Term	Definition
GO:0005509	calcium ion binding

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0008150	biological_process
cellular_component	GO:0005575	cellular_component
molecular_function	GO:0005509	calcium ion binding

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CmaCh04G019140.1	CmaCh04G019140.1	mRNA

InterPro

Analysis Name: InterPro Annotations of Cucurbita maxima
Date Performed: 2017-05-20


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002048	EF-hand domain	PFAM	PF13405	EF-hand_6	coord: 73..100 score: 3.
IPR002048	EF-hand domain	PROFILE	PS50222	EF_HAND_2	coord: 68..103 score: 12.589coord: 104..139 score: 6
IPR011992	EF-hand domain pair	GENE3D	G3DSA:1.10.238.10		coord: 6..133 score: 3.6
IPR011992	EF-hand domain pair	unknown	SSF47473	EF-hand	coord: 64..131 score: 4.85
IPR018247	EF-Hand 1, calcium-binding site	PROSITE	PS00018	EF_HAND_1	coord: 117..129 score: -coord: 81..93 scor
None	No IPR available	PANTHER	PTHR10891	EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN	coord: 64..136 score: 3.3
None	No IPR available	PANTHER	PTHR10891:SF592	CALCIUM-BINDING PROTEIN CML38-RELATED	coord: 64..136 score: 3.3

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
CmaCh04G019140	Cla001912	Watermelon (97103) v1	cmawmB739
CmaCh04G019140	Csa5G067670	Cucumber (Chinese Long) v2	cmacuB760
CmaCh04G019140	MELO3C026462	Melon (DHL92) v3.5.1	cmameB663
CmaCh04G019140	ClCG11G000380	Watermelon (Charleston Gray)	cmawcgB622
CmaCh04G019140	CSPI05G01480	Wild cucumber (PI 183967)	cmacpiB767
CmaCh04G019140	CmoCh04G020320	Cucurbita moschata (Rifu)	cmacmoB728
CmaCh04G019140	Lsi11G000760	Bottle gourd (USVL1VR-Ls)	cmalsiB635
CmaCh04G019140	Cp4.1LG01g16920	Cucurbita pepo (Zucchini)	cmacpeB732
CmaCh04G019140	CsaV3_5G015470	Cucumber (Chinese Long) v3	cmacucB0903
CmaCh04G019140	Cla97C11G206700	Watermelon (97103) v2	cmawmbB726
CmaCh04G019140	CsGy5G011640	Cucumber (Gy14) v2	cgybcmaB691

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
CmaCh04G019140	Cucumber (Chinese Long) v3	cmacucB0880
CmaCh04G019140	Watermelon (97103) v2	cmawmbB734
CmaCh04G019140	Wax gourd	cmawgoB0913
CmaCh04G019140	Wax gourd	cmawgoB0876
CmaCh04G019140	Wax gourd	cmawgoB0904
CmaCh04G019140	Melon (DHL92) v3.5.1	cmameB646
CmaCh04G019140	Watermelon (Charleston Gray)	cmawcgB628
CmaCh04G019140	Watermelon (97103) v1	cmawmB733
CmaCh04G019140	Watermelon (97103) v1	cmawmB735
CmaCh04G019140	Cucurbita pepo (Zucchini)	cmacpeB720
CmaCh04G019140	Cucurbita pepo (Zucchini)	cmacpeB725
CmaCh04G019140	Cucumber (Gy14) v2	cgybcmaB667
CmaCh04G019140	Melon (DHL92) v3.6.1	cmamedB730