MC05g1013 (gene) Bitter gourd (Dali-11) v1

Overview


Name	MC05g1013
Type	gene
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Hydroxymethylglutaryl-CoA lyase
Location	MC05: 13429516 .. 13432878 (+)
RNA-Seq Expression	MC05g1013
Synteny	MC05g1013

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: utr5CDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

GGAACTCGCCCATGGTTTTAATTACACCAACCTACGTGATTCCGTGCCAGATTTGTTGTAGTTCAATTCAATTGGGGGTATATCCATAATTACAGAATCTCTAAAATGTCAGAAAAGTTAAAATTGGATCAGTTGAGTCAATTTTTATAATTTAAGTTATTTGAGCAAAATAGAAAAATTTTTCAGGTCAGCTGAGTCAATTTCTCGATATTCTCTCGTACTCAAAATACAAAAACAAAAAAAGAAGAAAAAAATTAACCGACGCGAGCTCGAGCGACCAACCCAGCACCCTCACGACCTTCGGTATCTCCCTCGTGATCTTCGTCCTCCCGGCGGTACGATCCCCGACCGATCACACTCACGCCGACGGATCTTTCTGCGGCGGCGTAACCCCGACCCACGGCAGCCAGATATGCAGCGGTAACTTCCTTCCGGTCATAAACCAGCACAAACCGAAGCAATTTAAGCGGTAAAACTTTAGTTAACCAAGTTCGTTAACGTTGATTTAATTGGTTCTGTTTAGAATTCGGCCTGAATAGCTTCTGAACAATGAAAACCTCGTCTTTGTTTATTTTAGAAACTTCATTTCAGTCGAAATTTGTTTTCGTTAAAGGATTAAGATAAGTGGTTCCTTACTTGAATGGCTTGTTAAGTATGTAATTGATGCAAATTATTGATACTTAAGCCAGTTTTATAAACGTGGAGTTGATATAGCATGTTGGAATCGCTGATGAGAATATGTTTGGTGAATATACTGTGTGATGTATTTTCATGATGTGTGTAGTTATGAATTTTTGATATTGAAGTTGGATTATGGATTTGGGTTTTAGTTTCCTGAATCCTTGTGAAGAAAAATGCATAATTTGTTGAGTATGTGAAGCACATACTTTCATGATAGTAAAATGCATAATTAGTTTGGCTATGTTGAGCATATACATTCATATTAGTTTGGATTAGTTGAAAAGCAAGCATGTTGTTTCATTTAGACGAGATTGAATTTAGTATGCTTAAAGAAGAGGTTAATCTGGTTTACGCTTATCAAGAATTGGAATGGTATTAGTTTAGTCAATTTTATTATGTTGTGTAAGCTTGGTGACTATTGAAGTAGAACTTGCATTTTAAATAAGGATGGAGTCGTTTCAGTTTGATTTTTCATGCTAGTTTGATTGGAATTAAACGAAATGAACGAACACCAGTTCATTGATGGTTCAAAATTTATATGTTGAACCAATACATGAAATATATACATGTATACATGTCTATATAATCTTAGTTGGTTATAGAAGAAATTTTTTTTATGTAATCTTGACGTCGTCCTTTTTCTTGCTTTCTTACAATCTTACCAGATATTCATTGTTAGTATTGTTTACTGAAATGCAATGCAAGCTGCAAGGGTCTCTGCTAAATTGACTCGACGAGGTTTGTCTTGTTGCCATGCATATAATCCAACCATGGACACTTCAGGCCGATTTCTTGTTTCAACTTCTTCGCATGTGGGAGTCAACTTCTTCAAAAGACTTCCGATGAATAGCACAGAACGAGAAGTTGATGATTGCTGGTATGGACGAAAAACTTATTCATCTAAAACTCATGACCCAGTATATATGATTGCAATTATATAGTCTGATTATGATTTATGAGCTATGGGAAATCCTACAGTAAGTAGAATTAACCATAGCTTGTCGATTTGGTGTGACGTGAATATGGGCCATAGCTTTGAAGATTTTGTTTTGTATATAATTACTCGACTGTCAGCAATATCATGACTCATGGAAATGTGTTATAGGATTTTCCTTGGGTAAATGCAATAGAAACCTTACTTTGGGTCTGGTTAGGAAGAAACAACATTTGCATTTCCATTGAATATGTTGTTTAAGAAGAAACAACATATTCAATGGAAAGGCAAATGGTTGAAGGGGTTATTAGAATTAGAAAAATGTCAATTTCGCTTTGTTTTCCTACACATGGTGAATTTAACAATTACTGTCCCTTTGCAATTTATACAAATTAGGGCAGACTTCTGTAAGCTCTGTGGGGAGTTTGCTCCCTTATATGCATCATGCAATATACTTGGTTTATTGGGATCTGTAACTTGTGTACTAAAATCTAAAACTGTACTTTATCCATTATTACTTTTCTAATGACGTATACATTTAGATTAACCGTGGAATTTTTAGTATCTATTTCATGATTTTAAGTCTCATACTTTGGTTTGAATGTAACGCTGCATTTCTTCTTTCCAGTCAACAGGATGGAAGAGATGCAGCCCCTTTGAGAGAAAATAGCAGGAGATTGTCCCAGAGTGATATTCTAAAATGGGTAGTTCCTAGTACGAGATGTAAATATAGAGAGTCGAGTAATATTCATGACACCTGGCATTTATCGAATTGTCAAATGTCCACGATGACCTCAACAAAGGTGTTCCAAATTTTGGAATGACTTTTTTCCTTTGTTCTATTCTTGAGTTCCTATTCCAGTCAAGATCCCTATCCTTCTCTTATTTGTACCCTTGTCTCTTTATGTTATTCGCGAAAGAGTTGAAATGAGCTTTATTTTTTTTTAAATATCTGTAATTGTAACTTCTTGCAATGTTGTTTTCGATTGTAATTGTTATTGCCTATTATTGGGTTGTTTGATGAATTGTTGTTTCTGCTCTCCCAGTATTTATGCAATATTCCACAGTTCGTGAAGATTGTTGAAGTTGGTCCAAGAGACGGACTACAAAATGAAAAGCACATTATACCAACTTCTGTTAAGGTTGAATTGATAAAGATGCTAGTCTCTTCTGGGTTGCCTATTGTTGAAGCCACGAGTTTTGTCTCTCCAAAATGGGTACCGCAGGTAATTGGGTTTGATATTCTATGAACATGTTGATGGGTATATTTTCTGTTCCTGAAACAGTTCCTTTCTATCATTGTTCGTTCTTCTGGTGCTGCTCTTCCACTTTTCATGTGCTTTACCTTCATGTCTGTGTTTCTTGTACATATACTTATAATCTCCTGTCATATTTTCCTCATATTTTTCTCAGTTAGCAGATGCAAAAGATGTTATGGGGGGAATTAAAAATGTTGAAGGTGCTCGATTTCCTGTGTTAACTCCAAATATTAAAGTATGCATTCTTCAAGAGTAATAAAAAGTTAGGACTAATCTGGAAAGAATTTTGTGATAATTGATGAGGTTTTTGGATCTTTTTGTCTAGGGTTTTGAAGCAGCTGTTTCAGCTGGAGCAAAGGAAGTTGCCATCTTTGCTTCAGCTTCCGAATCCTTCTCAAAGTCAAACATAAATTGCAGCATAGAAGAAAGTCTACGCCGTTACCATGAAGTTGCTGTTGCTGCAAGAAAACACGCCCTTCCAGTTCGTGG

mRNA sequence

GGAACTCGCCCATGGTTTTAATTACACCAACCTACGTGATTCCGTGCCAGATTTGTTGTAGTTCAATTCAATTGGGGGTATATCCATAATTACAGAATCTCTAAAATGTCAGAAAAGTTAAAATTGGATCAGTTGAGTCAATTTTTATAATTTAAGTTATTTGAGCAAAATAGAAAAATTTTTCAGGTCAGCTGAGTCAATTTCTCGATATTCTCTCGTACTCAAAATACAAAAACAAAAAAAGAAGAAAAAAATTAACCGACGCGAGCTCGAGCGACCAACCCAGCACCCTCACGACCTTCGGTATCTCCCTCGTGATCTTCGTCCTCCCGGCGGTACGATCCCCGACCGATCACACTCACGCCGACGGATCTTTCTGCGGCGGCGTAACCCCGACCCACGGCAGCCAGATATGCAGCGGTAACTTCCTTCCGGTCATAAACCAGCACAAACCGAAGCAATTTAAGCGATATTCATTGTTAGTATTGTTTACTGAAATGCAATGCAAGCTGCAAGGGTCTCTGCTAAATTGACTCGACGAGGTTTGTCTTGTTGCCATGCATATAATCCAACCATGGACACTTCAGGCCGATTTCTTGTTTCAACTTCTTCGCATGTGGGAGTCAACTTCTTCAAAAGACTTCCGATGAATAGCACAGAACGAGAAGTTGATGATTGCTGTCAACAGGATGGAAGAGATGCAGCCCCTTTGAGAGAAAATAGCAGGAGATTGTCCCAGAGTGATATTCTAAAATGGTATTTATGCAATATTCCACAGTTCGTGAAGATTGTTGAAGTTGGTCCAAGAGACGGACTACAAAATGAAAAGCACATTATACCAACTTCTGTTAAGGTTGAATTGATAAAGATGCTAGTCTCTTCTGGGTTGCCTATTGTTGAAGCCACGAGTTTTGTCTCTCCAAAATGGGTACCGCAGTTAGCAGATGCAAAAGATGTTATGGGGGGAATTAAAAATGTTGAAGGTGCTCGATTTCCTGTGTTAACTCCAAATATTAAAGGTTTTGAAGCAGCTGTTTCAGCTGGAGCAAAGGAAGTTGCCATCTTTGCTTCAGCTTCCGAATCCTTCTCAAAGTCAAACATAAATTGCAGCATAGAAGAAAGTCTACGCCGTTACCATGAAGTTGCTGTTGCTGCAAGAAAACACGCCCTTCCAGTTCGTGG

Coding sequence (CDS)

ATGCAAGCTGCAAGGGTCTCTGCTAAATTGACTCGACGAGGTTTGTCTTGTTGCCATGCATATAATCCAACCATGGACACTTCAGGCCGATTTCTTGTTTCAACTTCTTCGCATGTGGGAGTCAACTTCTTCAAAAGACTTCCGATGAATAGCACAGAACGAGAAGTTGATGATTGCTGTCAACAGGATGGAAGAGATGCAGCCCCTTTGAGAGAAAATAGCAGGAGATTGTCCCAGAGTGATATTCTAAAATGGTATTTATGCAATATTCCACAGTTCGTGAAGATTGTTGAAGTTGGTCCAAGAGACGGACTACAAAATGAAAAGCACATTATACCAACTTCTGTTAAGGTTGAATTGATAAAGATGCTAGTCTCTTCTGGGTTGCCTATTGTTGAAGCCACGAGTTTTGTCTCTCCAAAATGGGTACCGCAGTTAGCAGATGCAAAAGATGTTATGGGGGGAATTAAAAATGTTGAAGGTGCTCGATTTCCTGTGTTAACTCCAAATATTAAAGGTTTTGAAGCAGCTGTTTCAGCTGGAGCAAAGGAAGTTGCCATCTTTGCTTCAGCTTCCGAATCCTTCTCAAAGTCAAACATAAATTGCAGCATAGAAGAAAGTCTACGCCGTTACCATGAAGTTGCTGTTGCTGCAAGAAAACACGCCCTTCCAGTTCGTGG

Protein sequence

MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCCQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR

Homology

[Close]

BLAST of MC05g1013 vs. ExPASy Swiss-Prot
Match: O81027 (Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Arabidopsis thaliana OX=3702 GN=HMGCL PE=1 SV=2)

HSP 1 Score: 221.5 bits (563), Expect = 9.8e-57
Identity = 111/137 (81.02%), Postives = 126/137 (91.97%), Query Frame = 0


Query: 90  IPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADA 149
           IP+FVKIVEVGPRDGLQNEK+I+PTSVKVELI+ LVSSGLP+VEATSFVSPKWVPQLADA
Sbjct: 164 IPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWVPQLADA 223

Query: 150 KDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLR 209
           KDVM  +  ++GAR PVLTPN+KGF+AAVSAGAKEVAIFASASESFS SNINC+IEESL 
Sbjct: 224 KDVMDAVNTLDGARLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINCTIEESLL 283

Query: 210 RYHEVAVAARKHALPVR 227
           RY  VA AA++H++PVR
Sbjct: 284 RYRVVATAAKEHSVPVR 300

[Close]

BLAST of MC05g1013 vs. ExPASy Swiss-Prot
Match: P35915 (Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Gallus gallus OX=9031 GN=HMGCL PE=1 SV=1)

HSP 1 Score: 188.0 bits (476), Expect = 1.2e-46
Identity = 91/136 (66.91%), Postives = 112/136 (82.35%), Query Frame = 0


Query: 91  PQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADAK 150
           PQ VK+VEVGPRDGLQNEK ++PT VK+ LI ML  +GLP++EATSFVSP+WVPQ+AD  
Sbjct: 3   PQRVKVVEVGPRDGLQNEKSVVPTPVKIRLIDMLSETGLPVIEATSFVSPRWVPQMADHA 62

Query: 151 DVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLRR 210
           +VM GI  + G  +PVLTPN+KGF+AAV+AGAKEV+IF +ASE F+K NINCSIEESL R
Sbjct: 63  EVMQGINKLPGVSYPVLTPNLKGFQAAVAAGAKEVSIFGAASELFTKKNINCSIEESLER 122

Query: 211 YHEVAVAARKHALPVR 227
           + EV  AAR  ++PVR
Sbjct: 123 FSEVMNAARAASIPVR 138

[Close]

BLAST of MC05g1013 vs. ExPASy Swiss-Prot
Match: Q29448 (Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Bos taurus OX=9913 GN=HMGCL PE=2 SV=2)

HSP 1 Score: 184.9 bits (468), Expect = 1.0e-45
Identity = 91/136 (66.91%), Postives = 112/136 (82.35%), Query Frame = 0


Query: 91  PQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADAK 150
           P+ VKIVEVGPRDGLQNEK+I+PT VK++LI ML  +GLP+VEATSFVSPKWVPQ+AD  
Sbjct: 30  PKQVKIVEVGPRDGLQNEKNIVPTPVKIKLIDMLSEAGLPVVEATSFVSPKWVPQMADHA 89

Query: 151 DVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLRR 210
           +V+ GI+   G  +PVLTPN KGF+AAV+AGAKEVAIF +ASE F+K NINCSI+ESL+R
Sbjct: 90  EVLKGIQKFPGVNYPVLTPNFKGFQAAVAAGAKEVAIFGAASELFTKKNINCSIDESLQR 149

Query: 211 YHEVAVAARKHALPVR 227
           + E+  AAR   + VR
Sbjct: 150 FDEILKAARAAGISVR 165

[Close]

BLAST of MC05g1013 vs. ExPASy Swiss-Prot
Match: A8WG57 (3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic OS=Danio rerio OX=7955 GN=hmgcll1 PE=2 SV=1)

HSP 1 Score: 183.3 bits (464), Expect = 3.0e-45
Identity = 89/140 (63.57%), Postives = 113/140 (80.71%), Query Frame = 0


Query: 87  LCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQL 146
           L  +P +VKIVEVGPRDGLQNEK I+PT VK++LI +L  +GLP++EATSFVS KWV Q+
Sbjct: 36  LPKLPVYVKIVEVGPRDGLQNEKEIVPTEVKIQLIDLLSQTGLPVIEATSFVSSKWVAQM 95

Query: 147 ADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEE 206
           AD   V+ GIK     R+PVLTPNI+GF+AAV+AGA EVA+F SASE+FS+ NINCSIEE
Sbjct: 96  ADHTAVLKGIKRSPDVRYPVLTPNIQGFQAAVAAGANEVAVFGSASETFSRKNINCSIEE 155

Query: 207 SLRRYHEVAVAARKHALPVR 227
           SL+R+ +V  AA++  +PVR
Sbjct: 156 SLQRFEQVVSAAKQEGIPVR 175

[Close]

BLAST of MC05g1013 vs. ExPASy Swiss-Prot
Match: P97519 (Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Hmgcl PE=2 SV=1)

HSP 1 Score: 180.6 bits (457), Expect = 1.9e-44
Identity = 88/137 (64.23%), Postives = 111/137 (81.02%), Query Frame = 0


Query: 90  IPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADA 149
           +P+ VKIVEVGPRDGLQNEK I+PT VK++LI ML  +GLP++EATSFVSPKWVPQ+AD 
Sbjct: 29  LPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADH 88

Query: 150 KDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLR 209
            DV+ GI+   G  +PVLTPN+KGFE AV+AGAKEV+IF +ASE F++ N+NCSIEES +
Sbjct: 89  SDVLKGIQKFPGINYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESFQ 148

Query: 210 RYHEVAVAARKHALPVR 227
           R+  V  AAR  ++ VR
Sbjct: 149 RFDGVMQAARAASISVR 165

[Close]

BLAST of MC05g1013 vs. NCBI nr
Match: XP_022153949.1 (hydroxymethylglutaryl-CoA lyase, mitochondrial-like [Momordica charantia] >XP_022153950.1 hydroxymethylglutaryl-CoA lyase, mitochondrial-like [Momordica charantia])

HSP 1 Score: 428 bits (1100), Expect = 1.60e-147
Identity = 226/259 (87.26%), Postives = 226/259 (87.26%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC 60
           MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC
Sbjct: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC 60

Query: 61  QQDGRDAAPLRENSRRLSQSDILKW---------------------------------YL 120
           QQDGRDAAPLRENSRRLSQSDILKW                                 YL
Sbjct: 61  QQDGRDAAPLRENSRRLSQSDILKWVVPSTRCKYRESSNIHDTWHLSNCQMSTMTSTKYL 120

Query: 121 CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA 180
           CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA
Sbjct: 121 CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA 180

Query: 181 DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES 226
           DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES
Sbjct: 181 DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES 240

[Close]

BLAST of MC05g1013 vs. NCBI nr
Match: KAG6580930.1 (Hydroxymethylglutaryl-CoA lyase, mitochondrial, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 330 bits (847), Expect = 6.36e-110
Identity = 182/227 (80.18%), Postives = 194/227 (85.46%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EVD+C
Sbjct: 1   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVDNC 60

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG DA   REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 61  CQQDGGDAVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 120

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL +VEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 121 LIKMLVSSGLRVVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 180

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKH+LPVR
Sbjct: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHSLPVR 218

[Close]

BLAST of MC05g1013 vs. NCBI nr
Match: XP_023526450.1 (hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [Cucurbita pepo subsp. pepo] >XP_023526451.1 hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 327 bits (839), Expect = 1.53e-108
Identity = 182/227 (80.18%), Postives = 192/227 (84.58%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV     L +     EVD+C
Sbjct: 1   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVTSTNGLGIQG---EVDNC 60

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG DA   REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 61  CQQDGGDAVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 120

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL IVEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 121 LIKMLVSSGLRIVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 180

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARKH+LPVR
Sbjct: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKHSLPVR 218

[Close]

BLAST of MC05g1013 vs. NCBI nr
Match: XP_022934490.1 (hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [Cucurbita moschata])

HSP 1 Score: 326 bits (835), Expect = 6.16e-108
Identity = 180/227 (79.30%), Postives = 192/227 (84.58%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EVD+C
Sbjct: 1   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVDNC 60

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG D    REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 61  CQQDGGDVVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 120

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL +VEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 121 LIKMLVSSGLRVVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 180

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARKH+LPVR
Sbjct: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKHSLPVR 218

[Close]

BLAST of MC05g1013 vs. NCBI nr
Match: XP_022983796.1 (hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X3 [Cucurbita maxima])

HSP 1 Score: 322 bits (825), Expect = 1.58e-107
Identity = 180/227 (79.30%), Postives = 191/227 (84.14%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EV +C
Sbjct: 2   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVHNC 61

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG DA   REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 62  CQQDGGDAVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 121

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL IVEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 122 LIKMLVSSGLRIVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 181

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARK +LPVR
Sbjct: 182 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKQSLPVR 219

[Close]

BLAST of MC05g1013 vs. ExPASy TrEMBL
Match: A0A6J1DIA6 (Hydroxymethylglutaryl-CoA lyase OS=Momordica charantia OX=3673 GN=LOC111021337 PE=3 SV=1)

HSP 1 Score: 428 bits (1100), Expect = 7.73e-148
Identity = 226/259 (87.26%), Postives = 226/259 (87.26%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC 60
           MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC
Sbjct: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSSHVGVNFFKRLPMNSTEREVDDCC 60

Query: 61  QQDGRDAAPLRENSRRLSQSDILKW---------------------------------YL 120
           QQDGRDAAPLRENSRRLSQSDILKW                                 YL
Sbjct: 61  QQDGRDAAPLRENSRRLSQSDILKWVVPSTRCKYRESSNIHDTWHLSNCQMSTMTSTKYL 120

Query: 121 CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA 180
           CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA
Sbjct: 121 CNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLA 180

Query: 181 DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES 226
           DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES
Sbjct: 181 DAKDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEES 240

[Close]

BLAST of MC05g1013 vs. ExPASy TrEMBL
Match: A0A6J1F7V0 (Hydroxymethylglutaryl-CoA lyase OS=Cucurbita moschata OX=3662 GN=LOC111441653 PE=3 SV=1)

HSP 1 Score: 326 bits (835), Expect = 2.98e-108
Identity = 180/227 (79.30%), Postives = 192/227 (84.58%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EVD+C
Sbjct: 1   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVDNC 60

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG D    REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 61  CQQDGGDVVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 120

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL +VEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 121 LIKMLVSSGLRVVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 180

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARKH+LPVR
Sbjct: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKHSLPVR 218

[Close]

BLAST of MC05g1013 vs. ExPASy TrEMBL
Match: A0A6J1J3E3 (Hydroxymethylglutaryl-CoA lyase OS=Cucurbita maxima OX=3661 GN=LOC111482306 PE=3 SV=1)

HSP 1 Score: 322 bits (825), Expect = 7.65e-108
Identity = 180/227 (79.30%), Postives = 191/227 (84.14%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EV +C
Sbjct: 2   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVHNC 61

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG DA   REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 62  CQQDGGDAVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 121

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL IVEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 122 LIKMLVSSGLRIVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 181

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARK +LPVR
Sbjct: 182 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKQSLPVR 219

[Close]

BLAST of MC05g1013 vs. ExPASy TrEMBL
Match: A0A6J1J8Q9 (Hydroxymethylglutaryl-CoA lyase OS=Cucurbita maxima OX=3661 GN=LOC111482306 PE=3 SV=1)

HSP 1 Score: 322 bits (825), Expect = 1.01e-106
Identity = 180/227 (79.30%), Postives = 191/227 (84.14%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTS-SHVGVNFFKRLPMNSTEREVDDC 60
           MQAA+VSAKLTRRGLS  H YNPTM  S RFL S+S SHVGV+    L +     EV +C
Sbjct: 2   MQAAKVSAKLTRRGLSWRHGYNPTMRISSRFLSSSSASHVGVSSTNGLGIQG---EVHNC 61

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
           CQQDG DA   REN RRLSQ      YL +IPQFVKIVEVGPRDGLQNEKHI+PT+VKVE
Sbjct: 62  CQQDGGDAVLSRENKRRLSQ------YLRHIPQFVKIVEVGPRDGLQNEKHIVPTAVKVE 121

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGL IVEATSFVSPKWVPQLADA DVM GI+NVEGARFPVLTPNIKGFEAAV+
Sbjct: 122 LIKMLVSSGLRIVEATSFVSPKWVPQLADANDVMEGIRNVEGARFPVLTPNIKGFEAAVA 181

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESLRRY EVAVAARK +LPVR
Sbjct: 182 AGAKEVAIFASASESFSKSNINCSIEESLRRYREVAVAARKQSLPVR 219

[Close]

BLAST of MC05g1013 vs. ExPASy TrEMBL
Match: A0A0A0LHM6 (Hydroxymethylglutaryl-CoA lyase OS=Cucumis sativus OX=3659 GN=Csa_3G823050 PE=3 SV=1)

HSP 1 Score: 300 bits (767), Expect = 5.93e-98
Identity = 167/227 (73.57%), Postives = 186/227 (81.94%), Query Frame = 0


Query: 1   MQAARVSAKLTRRGLSCCHAYNPTMDTSGRFLVSTSS-HVGVNFFKRLPMNSTEREVDDC 60
           MQAA++SAK TR+  S  HAYN +M+T   FLVS S+  VGV+   R P    +RE  +C
Sbjct: 1   MQAAKLSAKFTRQSFSWRHAYNLSMETPTPFLVSPSATDVGVSSI-RTP--GIQREFYNC 60

Query: 61  CQQDGRDAAPLRENSRRLSQSDILKWYLCNIPQFVKIVEVGPRDGLQNEKHIIPTSVKVE 120
            QQDGRDA   REN   LSQ      YLC IP FVKIVEVGPRDGLQNEKHI+PT+VKV+
Sbjct: 61  SQQDGRDAVLSRENKGGLSQ------YLCRIPPFVKIVEVGPRDGLQNEKHIVPTAVKVD 120

Query: 121 LIKMLVSSGLPIVEATSFVSPKWVPQLADAKDVMGGIKNVEGARFPVLTPNIKGFEAAVS 180
           LIKMLVSSGLP+VEATSFVSPKWVPQLADAK+VM GI+NVEGARFPVLTPN+KGFEAAV+
Sbjct: 121 LIKMLVSSGLPVVEATSFVSPKWVPQLADAKEVMEGIRNVEGARFPVLTPNLKGFEAAVA 180

Query: 181 AGAKEVAIFASASESFSKSNINCSIEESLRRYHEVAVAARKHALPVR 226
           AGAKEVAIFASASESFSKSNINCSIEESL RY +VA AARKH+LPVR
Sbjct: 181 AGAKEVAIFASASESFSKSNINCSIEESLHRYRQVADAARKHSLPVR 218

[Close]

BLAST of MC05g1013 vs. TAIR 10
Match: AT2G26800.1 (Aldolase superfamily protein )

HSP 1 Score: 221.5 bits (563), Expect = 7.0e-58
Identity = 111/137 (81.02%), Postives = 126/137 (91.97%), Query Frame = 0


Query: 90  IPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADA 149
           IP+FVKIVEVGPRDGLQNEK+I+PTSVKVELI+ LVSSGLP+VEATSFVSPKWVPQLADA
Sbjct: 129 IPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWVPQLADA 188

Query: 150 KDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLR 209
           KDVM  +  ++GAR PVLTPN+KGF+AAVSAGAKEVAIFASASESFS SNINC+IEESL 
Sbjct: 189 KDVMDAVNTLDGARLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINCTIEESLL 248

Query: 210 RYHEVAVAARKHALPVR 227
           RY  VA AA++H++PVR
Sbjct: 249 RYRVVATAAKEHSVPVR 265

[Close]

BLAST of MC05g1013 vs. TAIR 10
Match: AT2G26800.3 (Aldolase superfamily protein )

HSP 1 Score: 221.5 bits (563), Expect = 7.0e-58
Identity = 111/137 (81.02%), Postives = 126/137 (91.97%), Query Frame = 0


Query: 90  IPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADA 149
           IP+FVKIVEVGPRDGLQNEK+I+PTSVKVELI+ LVSSGLP+VEATSFVSPKWVPQLADA
Sbjct: 164 IPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWVPQLADA 223

Query: 150 KDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLR 209
           KDVM  +  ++GAR PVLTPN+KGF+AAVSAGAKEVAIFASASESFS SNINC+IEESL 
Sbjct: 224 KDVMDAVNTLDGARLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINCTIEESLL 283

Query: 210 RYHEVAVAARKHALPVR 227
           RY  VA AA++H++PVR
Sbjct: 284 RYRVVATAAKEHSVPVR 300

[Close]

BLAST of MC05g1013 vs. TAIR 10
Match: AT2G26800.2 (Aldolase superfamily protein )

HSP 1 Score: 221.5 bits (563), Expect = 7.0e-58
Identity = 111/137 (81.02%), Postives = 126/137 (91.97%), Query Frame = 0


Query: 90  IPQFVKIVEVGPRDGLQNEKHIIPTSVKVELIKMLVSSGLPIVEATSFVSPKWVPQLADA 149
           IP+FVKIVEVGPRDGLQNEK+I+PTSVKVELI+ LVSSGLP+VEATSFVSPKWVPQLADA
Sbjct: 164 IPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWVPQLADA 223

Query: 150 KDVMGGIKNVEGARFPVLTPNIKGFEAAVSAGAKEVAIFASASESFSKSNINCSIEESLR 209
           KDVM  +  ++GAR PVLTPN+KGF+AAVSAGAKEVAIFASASESFS SNINC+IEESL 
Sbjct: 224 KDVMDAVNTLDGARLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINCTIEESLL 283

Query: 210 RYHEVAVAARKHALPVR 227
           RY  VA AA++H++PVR
Sbjct: 284 RYRVVATAAKEHSVPVR 300

The following BLAST results are available for this feature:

BLAST of MC05g1013 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
O81027	9.8e-57	81.02	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Arabidopsis thaliana OX=3702 G...	[more]
P35915	1.2e-46	66.91	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Gallus gallus OX=9031 GN=HMGCL...	[more]
Q29448	1.0e-45	66.91	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Bos taurus OX=9913 GN=HMGCL PE...	[more]
A8WG57	3.0e-45	63.57	3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic OS=Danio rerio OX=7955 GN=hmgc...	[more]
P97519	1.9e-44	64.23	Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus norvegicus OX=10116 GN=...	[more]

BLAST of MC05g1013 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022153949.1	1.60e-147	87.26	hydroxymethylglutaryl-CoA lyase, mitochondrial-like [Momordica charantia] >XP_02...	[more]
KAG6580930.1	6.36e-110	80.18	Hydroxymethylglutaryl-CoA lyase, mitochondrial, partial [Cucurbita argyrosperma ...	[more]
XP_023526450.1	1.53e-108	80.18	hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [Cucurbita pepo s...	[more]
XP_022934490.1	6.16e-108	79.30	hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X1 [Cucurbita moscha...	[more]
XP_022983796.1	1.58e-107	79.30	hydroxymethylglutaryl-CoA lyase, mitochondrial-like isoform X3 [Cucurbita maxima...	[more]

BLAST of MC05g1013 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1DIA6	7.73e-148	87.26	Hydroxymethylglutaryl-CoA lyase OS=Momordica charantia OX=3673 GN=LOC111021337 P...	[more]
A0A6J1F7V0	2.98e-108	79.30	Hydroxymethylglutaryl-CoA lyase OS=Cucurbita moschata OX=3662 GN=LOC111441653 PE...	[more]
A0A6J1J3E3	7.65e-108	79.30	Hydroxymethylglutaryl-CoA lyase OS=Cucurbita maxima OX=3661 GN=LOC111482306 PE=3...	[more]
A0A6J1J8Q9	1.01e-106	79.30	Hydroxymethylglutaryl-CoA lyase OS=Cucurbita maxima OX=3661 GN=LOC111482306 PE=3...	[more]
A0A0A0LHM6	5.93e-98	73.57	Hydroxymethylglutaryl-CoA lyase OS=Cucumis sativus OX=3659 GN=Csa_3G823050 PE=3 ...	[more]

BLAST of MC05g1013 vs. TAIR 10


Match Name	E-value	Identity	Description
AT2G26800.1	7.0e-58	81.02	Aldolase superfamily protein	[more]
AT2G26800.3	7.0e-58	81.02	Aldolase superfamily protein	[more]
AT2G26800.2	7.0e-58	81.02	Aldolase superfamily protein	[more]

InterPro

Analysis Name: InterPro Annotations of Bitter gourd (Dali-11) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000891	Pyruvate carboxyltransferase	PFAM	PF00682	HMGL-like	coord: 94..222 e-value: 7.7E-18 score: 65.0
IPR013785	Aldolase-type TIM barrel	GENE3D	3.20.20.70	Aldolase class I	coord: 90..226 e-value: 6.5E-47 score: 162.3
None	No IPR available	PANTHER	PTHR42738:SF15	HYDROXYMETHYLGLUTARYL-COA LYASE	coord: 53..226
None	No IPR available	SUPERFAMILY	51569	Aldolase	coord: 85..225
IPR043594	HMG-CoA lyase	PANTHER	PTHR42738	HYDROXYMETHYLGLUTARYL-COA LYASE	coord: 53..226

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MC05g1013.1	MC05g1013.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0046951	ketone body biosynthetic process
biological_process	GO:0006552	leucine catabolic process
biological_process	GO:0006629	lipid metabolic process
molecular_function	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
molecular_function	GO:0003824	catalytic activity
molecular_function	GO:0016833	oxo-acid-lyase activity