Lag0027230 (gene) Sponge gourd (AG‐4) v1

Overview


Name	Lag0027230
Type	gene
Organism	Luffa acutangula (Sponge gourd (AG‐4) v1)
Description	Laccase
Location	chr10: 46006410 .. 46007048 (+)
RNA-Seq Expression	Lag0027230
Synteny	Lag0027230

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGCCCACAACCGCTCTTCTACAAGCACATTTCTTCAAAATCAATGGCGTTTTCACCACAGATTTTCCAGGAAACCCCCCTCACAAATTCAACTACACAGGCCCCGGACCTAAAAATTTGCAGACGACAAGTGGAACCAAGGTCTACAAATTACAATACAACTCCACAGTGGAATTAGTTCTACAAGATACAGGAATCATAACCCCAGAAAACCATCCCATTCATCTCCACGGATTCAATTTCTTCGAAGTCGGGCGAGGAATCGGCAATTTCAACCCTAAAACAGACCCCAAGAAATTCAATCTCGTGGATCCGGTGGAGAGAAACACAATCGGAGTTCCATCCGGTGGATGGACGGCGATAAGGTTTCGTGCGGACAATCCAGGTAAAAGAATTCGAATCATCTTTCGATTTCTCGATCAAATCTTAAACTATCGAACTGAATTTAAACGATTGAATTGAAAACGAAACTGAAATTGAAGGGTTTTGATTTCGTTTCACCTTGCAGGAGTTTGGTTTATGCATTGCCATTTGGAAATTCATACGACTTGGGGATTGAAGATGGCGTTCTTGGTGGAAAATGGCAAAGGCCCCAAACAGTCGCTGCTACCGCCGCCGAGCGACCTCCCAAAATGTTAA

mRNA sequence

ATGCCCACAACCGCTCTTCTACAAGCACATTTCTTCAAAATCAATGGCGTTTTCACCACAGATTTTCCAGGAAACCCCCCTCACAAATTCAACTACACAGGCCCCGGACCTAAAAATTTGCAGACGACAAGTGGAACCAAGGTCTACAAATTACAATACAACTCCACAGTGGAATTAGTTCTACAAGATACAGGAATCATAACCCCAGAAAACCATCCCATTCATCTCCACGGATTCAATTTCTTCGAAGTCGGGCGAGGAATCGGCAATTTCAACCCTAAAACAGACCCCAAGAAATTCAATCTCGTGGATCCGGTGGAGAGAAACACAATCGGAGTTCCATCCGGTGGATGGACGGCGATAAGGTTTCGTGCGGACAATCCAGGAGTTTGGTTTATGCATTGCCATTTGGAAATTCATACGACTTGGGGATTGAAGATGGCGTTCTTGGTGGAAAATGGCAAAGGCCCCAAACAGTCGCTGCTACCGCCGCCGAGCGACCTCCCAAAATGTTAA

Coding sequence (CDS)

ATGCCCACAACCGCTCTTCTACAAGCACATTTCTTCAAAATCAATGGCGTTTTCACCACAGATTTTCCAGGAAACCCCCCTCACAAATTCAACTACACAGGCCCCGGACCTAAAAATTTGCAGACGACAAGTGGAACCAAGGTCTACAAATTACAATACAACTCCACAGTGGAATTAGTTCTACAAGATACAGGAATCATAACCCCAGAAAACCATCCCATTCATCTCCACGGATTCAATTTCTTCGAAGTCGGGCGAGGAATCGGCAATTTCAACCCTAAAACAGACCCCAAGAAATTCAATCTCGTGGATCCGGTGGAGAGAAACACAATCGGAGTTCCATCCGGTGGATGGACGGCGATAAGGTTTCGTGCGGACAATCCAGGAGTTTGGTTTATGCATTGCCATTTGGAAATTCATACGACTTGGGGATTGAAGATGGCGTTCTTGGTGGAAAATGGCAAAGGCCCCAAACAGTCGCTGCTACCGCCGCCGAGCGACCTCCCAAAATGTTAA

Protein sequence

MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELVLQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTAIRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC

Homology

[Close]

BLAST of Lag0027230 vs. NCBI nr
Match: XP_038904173.1 (laccase-4-like [Benincasa hispida])

HSP 1 Score: 370.2 bits (949), Expect = 9.9e-99
Identity = 167/171 (97.66%), Postives = 169/171 (98.83%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MPTTALLQAHFFK  GVFTTDFPGNPPHKFNY+GPGPKNLQTTSGTK+YKLQYNSTVELV
Sbjct: 416 MPTTALLQAHFFKTKGVFTTDFPGNPPHKFNYSGPGPKNLQTTSGTKLYKLQYNSTVELV 475

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA
Sbjct: 476 LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 535

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC
Sbjct: 536 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 586

[Close]

BLAST of Lag0027230 vs. NCBI nr
Match: XP_023539306.1 (laccase-4-like [Cucurbita pepo subsp. pepo])

HSP 1 Score: 368.6 bits (945), Expect = 2.9e-98
Identity = 164/171 (95.91%), Postives = 169/171 (98.83%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MPTTALLQAHFFKINGVFTTDFPG PPHKFNYTGPGPKNLQTTSGTK+YKL+YNSTVELV
Sbjct: 387 MPTTALLQAHFFKINGVFTTDFPGKPPHKFNYTGPGPKNLQTTSGTKLYKLKYNSTVELV 446

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGI+TPENHPIHLHGFNFFEVGRG+GNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA
Sbjct: 447 LQDTGIVTPENHPIHLHGFNFFEVGRGVGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 506

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLEIHTTWGLKMAF+VENGKGPK SLLPPPSDLPKC
Sbjct: 507 IRFRADNPGVWFMHCHLEIHTTWGLKMAFMVENGKGPKHSLLPPPSDLPKC 557

[Close]

BLAST of Lag0027230 vs. NCBI nr
Match: XP_022937901.1 (laccase-4-like [Cucurbita moschata])

HSP 1 Score: 367.9 bits (943), Expect = 4.9e-98
Identity = 164/171 (95.91%), Postives = 169/171 (98.83%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MPTTALLQAHFFKINGVFTTDFPG PPHKFNYTGPGPKNLQTTSGTK+YKL+YNSTVELV
Sbjct: 407 MPTTALLQAHFFKINGVFTTDFPGKPPHKFNYTGPGPKNLQTTSGTKLYKLKYNSTVELV 466

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGI+TPENHPIHLHGFNFFEVGRG+GNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA
Sbjct: 467 LQDTGIVTPENHPIHLHGFNFFEVGRGVGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 526

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLEIHTTWGLKMAF+VENGKGPKQSL PPPSDLPKC
Sbjct: 527 IRFRADNPGVWFMHCHLEIHTTWGLKMAFMVENGKGPKQSLPPPPSDLPKC 577

[Close]

BLAST of Lag0027230 vs. NCBI nr
Match: XP_022971405.1 (laccase-4-like [Cucurbita maxima])

HSP 1 Score: 367.5 bits (942), Expect = 6.4e-98
Identity = 164/171 (95.91%), Postives = 169/171 (98.83%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MPTTALLQAHFFKINGVFTTDFPG PPHKFNYTG GPKNLQTTSGTK+YKL+YNSTVELV
Sbjct: 427 MPTTALLQAHFFKINGVFTTDFPGKPPHKFNYTGAGPKNLQTTSGTKLYKLKYNSTVELV 486

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGI+TPENHPIHLHGFNFFEVGRG+GNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA
Sbjct: 487 LQDTGIVTPENHPIHLHGFNFFEVGRGVGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 546

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLEIHTTWGLKMAF+VENGKGPKQSLLPPPSDLPKC
Sbjct: 547 IRFRADNPGVWFMHCHLEIHTTWGLKMAFMVENGKGPKQSLLPPPSDLPKC 597

[Close]

BLAST of Lag0027230 vs. NCBI nr
Match: XP_022145678.1 (laccase-4-like [Momordica charantia])

HSP 1 Score: 363.6 bits (932), Expect = 9.2e-97
Identity = 162/171 (94.74%), Postives = 169/171 (98.83%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MPTTALLQAHFFKI+GVFTTDFPGNPPHKFNY+GPGP+NLQTTSGTK+YKLQYNSTVELV
Sbjct: 390 MPTTALLQAHFFKISGVFTTDFPGNPPHKFNYSGPGPRNLQTTSGTKLYKLQYNSTVELV 449

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGIIT ENHP+HLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA
Sbjct: 450 LQDTGIITAENHPVHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 509

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLE+HTTWGLKMAFLV+NGKGPKQSL PPPSDLPKC
Sbjct: 510 IRFRADNPGVWFMHCHLEVHTTWGLKMAFLVDNGKGPKQSLPPPPSDLPKC 560

[Close]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot
Match: O80434 (Laccase-4 OS=Arabidopsis thaliana OX=3702 GN=IRX12 PE=2 SV=2)

HSP 1 Score: 312.0 bits (798), Expect = 4.2e-84
Identity = 135/171 (78.95%), Postives = 149/171 (87.13%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MP TALL AH+F  +GVFTTDFP NPPH FNY+G    N+ T +GT++YKL YN+TV+LV
Sbjct: 388 MPKTALLPAHYFNTSGVFTTDFPKNPPHVFNYSGGSVTNMATETGTRLYKLPYNATVQLV 447

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTG+I PENHP+HLHGFNFFEVGRG+GNFN   DPK FNLVDPVERNTIGVPSGGW  
Sbjct: 448 LQDTGVIAPENHPVHLHGFNFFEVGRGLGNFNSTKDPKNFNLVDPVERNTIGVPSGGWVV 507

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLE+HTTWGLKMAFLVENGKGP QS+LPPP DLPKC
Sbjct: 508 IRFRADNPGVWFMHCHLEVHTTWGLKMAFLVENGKGPNQSILPPPKDLPKC 558

[Close]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot
Match: Q0IQU1 (Laccase-22 OS=Oryza sativa subsp. japonica OX=39947 GN=LAC22 PE=2 SV=2)

HSP 1 Score: 302.0 bits (772), Expect = 4.3e-81
Identity = 124/171 (72.51%), Postives = 153/171 (89.47%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MP+T +LQAH++ I GVFT DFP  P HKFNYTG GPKNLQT +GT+VY+L YN++V++V
Sbjct: 394 MPSTPILQAHYYNIPGVFTEDFPATPLHKFNYTGSGPKNLQTMNGTRVYRLPYNASVQVV 453

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTGII+PE+HPIHLHGFNFF VG+G+GN+NP+T P  FNL+DP+ERNTIGVP+GGWTA
Sbjct: 454 LQDTGIISPESHPIHLHGFNFFVVGKGVGNYNPRTSPSTFNLIDPIERNTIGVPTGGWTA 513

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFR+DNPGVWFMHCH E+HT+WGLKMAF+V+NGK P ++L+PPP DLP+C
Sbjct: 514 IRFRSDNPGVWFMHCHFEVHTSWGLKMAFVVDNGKRPSETLIPPPKDLPQC 564

[Close]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot
Match: Q6ID18 (Laccase-10 OS=Arabidopsis thaliana OX=3702 GN=LAC10 PE=2 SV=1)

HSP 1 Score: 295.8 bits (756), Expect = 3.1e-79
Identity = 129/171 (75.44%), Postives = 143/171 (83.63%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGPKNLQTTSGTKVYKLQYNSTVELV 60
           MP TALLQAH+F + G++TTDFP  P   F++TG  P NL T   TK+YKL YNSTV++V
Sbjct: 388 MPKTALLQAHYFNLTGIYTTDFPAKPRRVFDFTGKPPSNLATMKATKLYKLPYNSTVQVV 447

Query: 61  LQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWTA 120
           LQDTG + PENHPIHLHGFNFF VG G GN+N K D  KFNLVDPVERNT+GVPSGGW A
Sbjct: 448 LQDTGNVAPENHPIHLHGFNFFVVGLGTGNYNSKKDSNKFNLVDPVERNTVGVPSGGWAA 507

Query: 121 IRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           IRFRADNPGVWFMHCHLE+HTTWGLKMAFLVENGKGP QS+ PPPSDLPKC
Sbjct: 508 IRFRADNPGVWFMHCHLEVHTTWGLKMAFLVENGKGPNQSIRPPPSDLPKC 558

[Close]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot
Match: Q1PDH6 (Laccase-16 OS=Arabidopsis thaliana OX=3702 GN=LAC16 PE=2 SV=2)

HSP 1 Score: 286.6 bits (732), Expect = 1.9e-76
Identity = 126/173 (72.83%), Postives = 146/173 (84.39%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTGPGP--KNLQTTSGTKVYKLQYNSTVE 60
           MP TALLQAHFF I+GVFT DFP  P + ++YT P     N  T  GTK+Y+L YN+TV+
Sbjct: 394 MPKTALLQAHFFNISGVFTDDFPAKPSNPYDYTAPVKLGVNAATMKGTKLYRLPYNATVQ 453

Query: 61  LVLQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGW 120
           +VLQ+T +I  +NHP HLHGFNFFEVGRG+GNFNP+ DPK FNLVDPVERNT+GVP+GGW
Sbjct: 454 IVLQNTAMILSDNHPFHLHGFNFFEVGRGLGNFNPEKDPKAFNLVDPVERNTVGVPAGGW 513

Query: 121 TAIRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           TAIRF ADNPGVWFMHCHLE+HTTWGLKMAF+V+NG GP QSLLPPP+DLPKC
Sbjct: 514 TAIRFIADNPGVWFMHCHLELHTTWGLKMAFVVDNGHGPDQSLLPPPADLPKC 566

[Close]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot
Match: Q8RYM9 (Laccase-2 OS=Oryza sativa subsp. japonica OX=39947 GN=LAC2 PE=2 SV=1)

HSP 1 Score: 274.6 bits (701), Expect = 7.4e-73
Identity = 119/172 (69.19%), Postives = 143/172 (83.14%), Query Frame = 0


Query: 1   MPTTALLQAHFFKINGVFTTDFPGNPPHKFNYTG-PGPKNLQTTSGTKVYKLQYNSTVEL 60
           MP TALLQAH++   GVF  DFP  PP +FNYTG P    L T+ GT++ K+ YN+TVEL
Sbjct: 391 MPRTALLQAHYYGQKGVFAADFPDRPPARFNYTGVPLTAGLGTSLGTRLSKIAYNATVEL 450

Query: 61  VLQDTGIITPENHPIHLHGFNFFEVGRGIGNFNPKTDPKKFNLVDPVERNTIGVPSGGWT 120
           VLQDT +++ E+HP HLHG+NFF VGRG+GNF+P  DP K+NLVDP ERNT+GVP+GGWT
Sbjct: 451 VLQDTNLLSVESHPFHLHGYNFFVVGRGVGNFDPAKDPAKYNLVDPPERNTVGVPAGGWT 510

Query: 121 AIRFRADNPGVWFMHCHLEIHTTWGLKMAFLVENGKGPKQSLLPPPSDLPKC 172
           AIRFRADNPGVWF+HCHLE+HT+WGLKMAFLVE+G GP +S+LPPP DLPKC
Sbjct: 511 AIRFRADNPGVWFLHCHLEVHTSWGLKMAFLVEDGSGPDESVLPPPKDLPKC 562

The following BLAST results are available for this feature:

BLAST of Lag0027230 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_038904173.1	9.9e-99	97.66	laccase-4-like [Benincasa hispida]	[more]
XP_023539306.1	2.9e-98	95.91	laccase-4-like [Cucurbita pepo subsp. pepo]	[more]
XP_022937901.1	4.9e-98	95.91	laccase-4-like [Cucurbita moschata]	[more]
XP_022971405.1	6.4e-98	95.91	laccase-4-like [Cucurbita maxima]	[more]
XP_022145678.1	9.2e-97	94.74	laccase-4-like [Momordica charantia]	[more]

BLAST of Lag0027230 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
O80434	4.2e-84	78.95	Laccase-4 OS=Arabidopsis thaliana OX=3702 GN=IRX12 PE=2 SV=2	[more]
Q0IQU1	4.3e-81	72.51	Laccase-22 OS=Oryza sativa subsp. japonica OX=39947 GN=LAC22 PE=2 SV=2	[more]
Q6ID18	3.1e-79	75.44	Laccase-10 OS=Arabidopsis thaliana OX=3702 GN=LAC10 PE=2 SV=1	[more]
Q1PDH6	1.9e-76	72.83	Laccase-16 OS=Arabidopsis thaliana OX=3702 GN=LAC16 PE=2 SV=2	[more]
Q8RYM9	7.4e-73	69.19	Laccase-2 OS=Oryza sativa subsp. japonica OX=39947 GN=LAC2 PE=2 SV=1	[more]

InterPro

Analysis Name: InterPro Annotations of Sponge gourd (AG-4) v1
Date Performed: 2022-08-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR008972	Cupredoxin	GENE3D	2.60.40.420		coord: 1..171 e-value: 7.7E-57 score: 194.3
IPR008972	Cupredoxin	SUPERFAMILY	49503	Cupredoxins	coord: 2..171
IPR011706	Multicopper oxidase, C-terminal	PFAM	PF07731	Cu-oxidase_2	coord: 24..154 e-value: 9.3E-42 score: 142.0
IPR045087	Multicopper oxidase	PANTHER	PTHR11709	MULTI-COPPER OXIDASE	coord: 1..171
None	No IPR available	PANTHER	PTHR11709:SF368	LACCASE	coord: 1..171
IPR002355	Multicopper oxidase, copper-binding site	PROSITE	PS00080	MULTICOPPER_OXIDASE2	coord: 134..145
IPR033138	Multicopper oxidases, conserved site	PROSITE	PS00079	MULTICOPPER_OXIDASE1	coord: 129..149
IPR034289	Laccase, third cupredoxin domain	CDD	cd13897	CuRO_3_LCC_plant	coord: 17..154 e-value: 1.01265E-87 score: 251.41

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Lag0027230.1	Lag0027230.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0046274	lignin catabolic process
cellular_component	GO:0048046	apoplast
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005507	copper ion binding
molecular_function	GO:0052716	hydroquinone:oxygen oxidoreductase activity
molecular_function	GO:0016491	oxidoreductase activity