IVF0015248 (gene) Melon (IVF77) v1

Overview
NameIVF0015248
Typegene
OrganismCucumis melo L. ssp. agrestis cv. IVF77 (Melon (IVF77) v1)
DescriptionIAA-amino acid hydrolase ILR1-like 3
Locationchr08: 14580273 .. 14580485 (+)
RNA-Seq ExpressionIVF0015248
SyntenyIVF0015248
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGGAGCAGAGGATTTCAGCTTCTACTCCCAACACATTCCTGTTGTATTTTTCATGATCAGAGCGAAGAACGATATGATGAAATCCGGAATACCGTTGCACTTGCCCTACCTTGTCTTGGATGAACAAGTTCTTCCACTTGGAGCTTCTCTTCATGCTGCTGTTGCAATTTCTTACTTAGCTCAACAACATTATTTTGTTTCCAGTAATTAA

mRNA sequence

ATGGGAGCAGAGGATTTCAGCTTCTACTCCCAACACATTCCTGTTGTATTTTTCATGATCAGAGCGAAGAACGATATGATGAAATCCGGAATACCGTTGCACTTGCCCTACCTTGTCTTGGATGAACAAGTTCTTCCACTTGGAGCTTCTCTTCATGCTGCTGTTGCAATTTCTTACTTAGCTCAACAACATTATTTTGTTTCCAGTAATTAA

Coding sequence (CDS)

ATGGGAGCAGAGGATTTCAGCTTCTACTCCCAACACATTCCTGTTGTATTTTTCATGATCAGAGCGAAGAACGATATGATGAAATCCGGAATACCGTTGCACTTGCCCTACCTTGTCTTGGATGAACAAGTTCTTCCACTTGGAGCTTCTCTTCATGCTGCTGTTGCAATTTCTTACTTAGCTCAACAACATTATTTTGTTTCCAGTAATTAA

Protein sequence

MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYLAQQHYFVSSN
Homology
BLAST of IVF0015248 vs. ExPASy Swiss-Prot
Match: Q8H3C9 (IAA-amino acid hydrolase ILR1-like 7 OS=Oryza sativa subsp. japonica OX=39947 GN=ILL7 PE=2 SV=1)

HSP 1 Score: 73.6 bits (179), Expect = 1.0e-12
Identity = 37/70 (52.86%), Postives = 50/70 (71.43%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKND-MMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISY 60
           MG+EDF+FY+Q  P  FFMI   N+  M+   PLH P+ V+DE VLP+GA+LHAAVA+ Y
Sbjct: 386 MGSEDFAFYAQRFPAAFFMIGVGNETTMRKVYPLHSPHFVVDEDVLPVGAALHAAVAMEY 445

Query: 61  LAQQHYFVSS 70
           L  +H F ++
Sbjct: 446 L-NKHAFTAT 454

BLAST of IVF0015248 vs. ExPASy Swiss-Prot
Match: P54968 (IAA-amino acid hydrolase ILR1 OS=Arabidopsis thaliana OX=3702 GN=ILR1 PE=1 SV=2)

HSP 1 Score: 71.6 bits (174), Expect = 3.9e-12
Identity = 31/60 (51.67%), Postives = 44/60 (73.33%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MG EDFSF++Q      F++  KN+ + +G PLH PY  +DE+ LP+GA+LHAA+A+SYL
Sbjct: 368 MGGEDFSFFTQKTKAAIFVLGVKNETLGAGKPLHSPYFFVDEEALPVGAALHAAMAVSYL 427

BLAST of IVF0015248 vs. ExPASy Swiss-Prot
Match: Q5Z678 (IAA-amino acid hydrolase ILR1-like 6 OS=Oryza sativa subsp. japonica OX=39947 GN=ILL6 PE=2 SV=1)

HSP 1 Score: 67.8 bits (164), Expect = 5.6e-11
Identity = 35/70 (50.00%), Postives = 45/70 (64.29%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQ +P  F+ I  +N+ + S    H PY ++DE VLP GA+ HAA+A  YL
Sbjct: 428 MGAEDFSFYSQVVPAGFYYIGVRNETLGSVHTGHSPYFMIDEDVLPTGAAFHAAIAERYL 487

Query: 61  AQQHYFVSSN 71
           A      SS+
Sbjct: 488 ANHSPSSSSS 497

BLAST of IVF0015248 vs. ExPASy Swiss-Prot
Match: Q8VYX0 (IAA-amino acid hydrolase ILR1-like 6 OS=Arabidopsis thaliana OX=3702 GN=ILL6 PE=1 SV=2)

HSP 1 Score: 65.5 bits (158), Expect = 2.8e-10
Identity = 31/64 (48.44%), Postives = 44/64 (68.75%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDF+FYS+ IP  F+ I  +N+ + S    H P+ ++DE  LP+GA++HAAVA  YL
Sbjct: 400 MGAEDFAFYSEIIPAAFYFIGIRNEELGSVHIAHSPHFMIDEDSLPVGAAVHAAVAERYL 459

Query: 61  AQQH 65
             +H
Sbjct: 460 NDKH 463

BLAST of IVF0015248 vs. ExPASy Swiss-Prot
Match: Q851L5 (IAA-amino acid hydrolase ILR1-like 3 OS=Oryza sativa subsp. japonica OX=39947 GN=ILL3 PE=2 SV=1)

HSP 1 Score: 63.9 bits (154), Expect = 8.1e-10
Identity = 34/65 (52.31%), Postives = 41/65 (63.08%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKND-----MMKSGIPLHLPYLVLDEQVLPLGASLHAAV 60
           MGAEDF FY+Q IP  FF I   ND        +   LH P+ V+DE+ LP+GA+ HAAV
Sbjct: 344 MGAEDFGFYAQRIPAAFFGIGVGNDGGGMAETTTKNQLHSPHFVVDEEALPVGAAFHAAV 403

BLAST of IVF0015248 vs. ExPASy TrEMBL
Match: A0A5D3D8C0 (IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold307G00180 PE=4 SV=1)

HSP 1 Score: 137.5 bits (345), Expect = 2.1e-29
Identity = 68/68 (100.00%), Postives = 68/68 (100.00%), Query Frame = 0

Query: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
          MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL
Sbjct: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60

Query: 61 AQQHYFVS 69
          AQQHYFVS
Sbjct: 61 AQQHYFVS 68

BLAST of IVF0015248 vs. ExPASy TrEMBL
Match: A0A5A7TV97 (IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold294G00420 PE=4 SV=1)

HSP 1 Score: 136.7 bits (343), Expect = 3.6e-29
Identity = 68/70 (97.14%), Postives = 68/70 (97.14%), Query Frame = 0

Query: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
          MGAEDFSFYSQHIP VFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL
Sbjct: 1  MGAEDFSFYSQHIPAVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60

Query: 61 AQQHYFVSSN 71
          AQQHY VSSN
Sbjct: 61 AQQHYSVSSN 70

BLAST of IVF0015248 vs. ExPASy TrEMBL
Match: A0A0A0LGQ7 (M20_dimer domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_3G778230 PE=3 SV=1)

HSP 1 Score: 122.1 bits (305), Expect = 9.3e-25
Identity = 60/70 (85.71%), Postives = 63/70 (90.00%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQHIP  FFMI AKND M+SGIPLH PYLVLDE VLPLGA+LHAAVAISYL
Sbjct: 366 MGAEDFSFYSQHIPAAFFMIGAKNDTMESGIPLHSPYLVLDEHVLPLGAALHAAVAISYL 425

Query: 61  AQQHYFVSSN 71
            QQH+FVSSN
Sbjct: 426 DQQHHFVSSN 435

BLAST of IVF0015248 vs. ExPASy TrEMBL
Match: A0A5A7TLW9 (IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold352G004230 PE=3 SV=1)

HSP 1 Score: 101.3 bits (251), Expect = 1.7e-18
Identity = 54/70 (77.14%), Postives = 57/70 (81.43%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQ IP VFFMI AKND M S IPLH PYL+LDE+VLPLGA+LHA VAISYL
Sbjct: 346 MGAEDFSFYSQQIPAVFFMIGAKNDTMDSRIPLHSPYLILDEEVLPLGAALHAVVAISYL 405

Query: 61  AQQHYFVSSN 71
            Q    VSSN
Sbjct: 406 DQ--LSVSSN 413

BLAST of IVF0015248 vs. ExPASy TrEMBL
Match: A0A1S3B6R3 (IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo OX=3656 GN=LOC103486646 PE=3 SV=1)

HSP 1 Score: 101.3 bits (251), Expect = 1.7e-18
Identity = 54/70 (77.14%), Postives = 57/70 (81.43%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQ IP VFFMI AKND M S IPLH PYL+LDE+VLPLGA+LHA VAISYL
Sbjct: 366 MGAEDFSFYSQQIPAVFFMIGAKNDTMDSRIPLHSPYLILDEEVLPLGAALHAVVAISYL 425

Query: 61  AQQHYFVSSN 71
            Q    VSSN
Sbjct: 426 DQ--LSVSSN 433

BLAST of IVF0015248 vs. NCBI nr
Match: KAA0045441.1 (IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa])

HSP 1 Score: 136 bits (343), Expect = 2.53e-40
Identity = 68/70 (97.14%), Postives = 68/70 (97.14%), Query Frame = 0

Query: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
          MGAEDFSFYSQHIP VFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL
Sbjct: 1  MGAEDFSFYSQHIPAVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60

Query: 61 AQQHYFVSSN 70
          AQQHY VSSN
Sbjct: 61 AQQHYSVSSN 70

BLAST of IVF0015248 vs. NCBI nr
Match: TYK19792.1 (IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa])

HSP 1 Score: 137 bits (345), Expect = 4.75e-40
Identity = 68/68 (100.00%), Postives = 68/68 (100.00%), Query Frame = 0

Query: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
          MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL
Sbjct: 1  MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60

Query: 61 AQQHYFVS 68
          AQQHYFVS
Sbjct: 61 AQQHYFVS 68

BLAST of IVF0015248 vs. NCBI nr
Match: XP_004136497.2 (IAA-amino acid hydrolase ILR1-like 3 [Cucumis sativus] >KAE8651096.1 hypothetical protein Csa_001046 [Cucumis sativus])

HSP 1 Score: 122 bits (305), Expect = 1.28e-30
Identity = 60/70 (85.71%), Postives = 63/70 (90.00%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQHIP  FFMI AKND M+SGIPLH PYLVLDE VLPLGA+LHAAVAISYL
Sbjct: 424 MGAEDFSFYSQHIPAAFFMIGAKNDTMESGIPLHSPYLVLDEHVLPLGAALHAAVAISYL 483

Query: 61  AQQHYFVSSN 70
            QQH+FVSSN
Sbjct: 484 DQQHHFVSSN 493

BLAST of IVF0015248 vs. NCBI nr
Match: XP_038906100.1 (IAA-amino acid hydrolase ILR1-like 3 [Benincasa hispida])

HSP 1 Score: 108 bits (270), Expect = 6.88e-26
Identity = 54/65 (83.08%), Postives = 56/65 (86.15%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQHIP  FFMI AKN  M SGIPLH PYLVLDEQVLPLGA+LHAAVAISYL
Sbjct: 362 MGAEDFSFYSQHIPAAFFMIGAKNITMDSGIPLHSPYLVLDEQVLPLGAALHAAVAISYL 421

Query: 61  AQQHY 65
            Q H+
Sbjct: 422 DQHHH 426

BLAST of IVF0015248 vs. NCBI nr
Match: KAA0043848.1 (IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa] >TYK25287.1 IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa])

HSP 1 Score: 101 bits (251), Expect = 3.00e-23
Identity = 54/70 (77.14%), Postives = 57/70 (81.43%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDFSFYSQ IP VFFMI AKND M S IPLH PYL+LDE+VLPLGA+LHA VAISYL
Sbjct: 346 MGAEDFSFYSQQIPAVFFMIGAKNDTMDSRIPLHSPYLILDEEVLPLGAALHAVVAISYL 405

Query: 61  AQQHYFVSSN 70
            Q    VSSN
Sbjct: 406 DQLS--VSSN 413

BLAST of IVF0015248 vs. TAIR 10
Match: AT3G02875.1 (Peptidase M20/M25/M40 family protein )

HSP 1 Score: 71.6 bits (174), Expect = 2.8e-13
Identity = 31/60 (51.67%), Postives = 44/60 (73.33%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MG EDFSF++Q      F++  KN+ + +G PLH PY  +DE+ LP+GA+LHAA+A+SYL
Sbjct: 368 MGGEDFSFFTQKTKAAIFVLGVKNETLGAGKPLHSPYFFVDEEALPVGAALHAAMAVSYL 427

BLAST of IVF0015248 vs. TAIR 10
Match: AT1G44350.1 (IAA-leucine resistant (ILR)-like gene 6 )

HSP 1 Score: 65.5 bits (158), Expect = 2.0e-11
Identity = 31/64 (48.44%), Postives = 44/64 (68.75%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MGAEDF+FYS+ IP  F+ I  +N+ + S    H P+ ++DE  LP+GA++HAAVA  YL
Sbjct: 400 MGAEDFAFYSEIIPAAFYFIGIRNEELGSVHIAHSPHFMIDEDSLPVGAAVHAAVAERYL 459

Query: 61  AQQH 65
             +H
Sbjct: 460 NDKH 463

BLAST of IVF0015248 vs. TAIR 10
Match: AT1G51760.1 (peptidase M20/M25/M40 family protein )

HSP 1 Score: 56.2 bits (134), Expect = 1.2e-08
Identity = 28/62 (45.16%), Postives = 38/62 (61.29%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MG+EDFSFY Q IP  F  +  +N         H PY  ++E++LP GASLHA++A  YL
Sbjct: 364 MGSEDFSFYQQAIPGHFSFVGMQNKARSPMASPHSPYFEVNEELLPYGASLHASMATRYL 423

Query: 61  AQ 63
            +
Sbjct: 424 LE 425

BLAST of IVF0015248 vs. TAIR 10
Match: AT5G54140.1 (IAA-leucine-resistant (ILR1)-like 3 )

HSP 1 Score: 54.7 bits (130), Expect = 3.5e-08
Identity = 29/64 (45.31%), Postives = 40/64 (62.50%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           M  EDF+FY Q IP  +  I  +N+ + S   +H PY  LDE VLP+G++  AA+A  YL
Sbjct: 358 MAGEDFAFYQQKIPGYYIGIGIRNEEIGSVRSVHSPYFFLDENVLPIGSATFAALAEMYL 417

Query: 61  AQQH 65
            Q+H
Sbjct: 418 -QEH 420

BLAST of IVF0015248 vs. TAIR 10
Match: AT5G56650.1 (IAA-leucine resistant (ILR)-like 1 )

HSP 1 Score: 47.4 bits (111), Expect = 5.6e-06
Identity = 23/60 (38.33%), Postives = 38/60 (63.33%), Query Frame = 0

Query: 1   MGAEDFSFYSQHIPVVFFMIRAKNDMMKSGIPLHLPYLVLDEQVLPLGASLHAAVAISYL 60
           MG+EDFS++++ IP  F ++    D  +     H P+  ++E VLP GA++HA +A+ YL
Sbjct: 364 MGSEDFSYFAETIPGHFSLL-GMQDETQGYASSHSPHYRINEDVLPYGAAIHATMAVQYL 422

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q8H3C91.0e-1252.86IAA-amino acid hydrolase ILR1-like 7 OS=Oryza sativa subsp. japonica OX=39947 GN... [more]
P549683.9e-1251.67IAA-amino acid hydrolase ILR1 OS=Arabidopsis thaliana OX=3702 GN=ILR1 PE=1 SV=2[more]
Q5Z6785.6e-1150.00IAA-amino acid hydrolase ILR1-like 6 OS=Oryza sativa subsp. japonica OX=39947 GN... [more]
Q8VYX02.8e-1048.44IAA-amino acid hydrolase ILR1-like 6 OS=Arabidopsis thaliana OX=3702 GN=ILL6 PE=... [more]
Q851L58.1e-1052.31IAA-amino acid hydrolase ILR1-like 3 OS=Oryza sativa subsp. japonica OX=39947 GN... [more]
Match NameE-valueIdentityDescription
A0A5D3D8C02.1e-29100.00IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E... [more]
A0A5A7TV973.6e-2997.14IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E... [more]
A0A0A0LGQ79.3e-2585.71M20_dimer domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_3G778230 P... [more]
A0A5A7TLW91.7e-1877.14IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E... [more]
A0A1S3B6R31.7e-1877.14IAA-amino acid hydrolase ILR1-like 3 OS=Cucumis melo OX=3656 GN=LOC103486646 PE=... [more]
Match NameE-valueIdentityDescription
KAA0045441.12.53e-4097.14IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa][more]
TYK19792.14.75e-40100.00IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa][more]
XP_004136497.21.28e-3085.71IAA-amino acid hydrolase ILR1-like 3 [Cucumis sativus] >KAE8651096.1 hypothetica... [more]
XP_038906100.16.88e-2683.08IAA-amino acid hydrolase ILR1-like 3 [Benincasa hispida][more]
KAA0043848.13.00e-2377.14IAA-amino acid hydrolase ILR1-like 3 [Cucumis melo var. makuwa] >TYK25287.1 IAA-... [more]
Match NameE-valueIdentityDescription
AT3G02875.12.8e-1351.67Peptidase M20/M25/M40 family protein [more]
AT1G44350.12.0e-1148.44IAA-leucine resistant (ILR)-like gene 6 [more]
AT1G51760.11.2e-0845.16peptidase M20/M25/M40 family protein [more]
AT5G54140.13.5e-0845.31IAA-leucine-resistant (ILR1)-like 3 [more]
AT5G56650.15.6e-0638.33IAA-leucine resistant (ILR)-like 1 [more]
InterPro
Analysis Name: InterPro Annotations of Melon (IVF77) v1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D3.40.630.10Zn peptidasescoord: 1..70
e-value: 2.6E-15
score: 58.1
NoneNo IPR availablePANTHERPTHR11014:SF108IAA-AMINO ACID HYDROLASE ILR1coord: 1..64
NoneNo IPR availableSUPERFAMILY53187Zn-dependent exopeptidasescoord: 1..62
IPR017439AmidohydrolasePANTHERPTHR11014PEPTIDASE M20 FAMILY MEMBERcoord: 1..64

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
IVF0015248.1IVF0015248.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0009850 auxin metabolic process
molecular_function GO:0010179 IAA-Ala conjugate hydrolase activity
molecular_function GO:0016787 hydrolase activity