Carg17502 (gene) Silver-seed gourd (SMH-JMG-627) v2

Overview


Name	Carg17502
Type	gene
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	Heat shock protein DnaJ, cysteine-rich domain-containing protein
Location	Carg_Chr12: 11315971 .. 11320128 (-)
RNA-Seq Expression	Carg17502
Synteny	Carg17502

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDSthree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGTTCTTGGATCAGCTCGAGGTTCCTCGTTCCGTGGATAGTTTGAGTTTACTGATTTTTTTCCCTCAATTTTCAGGTGCTGTCCAATGTGCTCAGTGTCAAGGAACAGGAGTGAATTCAGAGGATCACTTCAATGGACGGTTTAAAGCTGGTGGCTTATGCTGGTTGTGCAGGTATGCACAAAAAGCTCTACCTGCTTTTAATGATATTTTGTCCACCTTACTCTTTAGTAGAACTATAAATTACCATTAGCATGTCCTTAAACTCTCACAAGCTCGACTCGGGAGCTAAAAAGGTCAAATTTATGTTATGTGGGTTAAAGTCCGATTCTGATGACTCATCTATTTAGAGGGCGTTTAGCTCTAACTAGAGTGTTGTAACTCAGAGTTGAAAAGGTCGAACTTATGTTTTGTGGCTTAAAGTCTGATTCTGATGAGTCAATGAGTCATCTCCTTAGAGGGCGTTTAGCTCTCTAACTAGAGTATTGTAGCTCAGAGCTAAAAAAGTCAAACTTGTGTTATGTGGGTTAAAGTCCGATTCTGATGATTCAATGAGTCATGTACTTAGAGGACGTTTAGCTCACTAACTAGAGTATCGTAACTCAGAGCTAAAAAAGTCGAACTTGTGTTATGTGGGTTAAAGTCCGATTTTGATGATTCAATGAGTCATCTACTTAAAGGGCATTTAGCTCATGAGCTAGAGTACTATAACTCGGAGCTAAAAGGGTCAAATTTATGTTATGTGTGTTAAAGCCTGATTCTCATGACTCAATGAGTCATCTACTTAGAGGGTGTTTAACTCACGGACTAGAGTACTGTAACTCGGAGCTGAAAAGGTCGAACTTATGTTATGTGGGTTAAAGTCCAATTTTGATGATTCCATGAGTCATCTACTTAGAGGACGTTTAGCTCTCTAACTAGAGTGCAGTAACTCAGAGCTTAAAAGGTCGAACTTATGTTATGTGGGTTAAAGTTCGAATCTGATAACTCAATGAGTCATCTACTTAGAGGACATTTAGCTCACTAACTAGAGTACTGTAACTCGGAGCTAAAAAGGTCGAACTTATGTTATGTGGGTTAAAGTCCAATTATGATGACTCAACGAGTCATCGACTTAGAGGGTGTTTAGCTCACTAACTAGAGTACTACAACTCAGAGCTAAAAAAGTCAAACACCTTGTGTTATGTGGGTTAAAGTCCGATTCTGATGACTCAATGAGTCATCTACTTAGAGGGCGTTTAGTTCACTGTAACTCAGAGCTAAAAAGGTCGAACTTATGTTATGTGGATTAAAGTCCAGTTTCAATGACGACCTTGATGAGTCATCTACTCAAAGGACGTCTGTCTCACAAACTAGACTACTGTAACCCGAAGCTAAAAAGATCAAGCTTATGTCATCCGGGTCAAAACCATTACATCTATTATCCACGAGTCTAGTCAAGTATGCATAATCACGACCATGGTTCATTTCGGGTCTTTCGGGATTTCGTATAGAATTAACGATACTGAGGGTACCGTGATGAACATTGCAGAGGCAAAAGGGACATCCTGTGTGGTGGCTGTAATGGAGCAGGTTTTGTGGGTGGATTCATGAGTACAGCTGATAGTTAGTTCTTTCAGCTGCACCACAAATTTGAGTATTTTAAGATGAAAAAAGCCTATTAGTTTCAGTAATTTTGTATAATGGGTCACATTATTTCTAAGTTTGTATTTCAAAATTATGAATGTTCTTGTTTTGCTATATTGTTTTGTTGCATAATTTGAGATCGTTGAACGTAATGAATGGTTTTTACACGATTTTAGGTTTTTTAACGATGAAAATTGCCTATTTTTTGTTATGAATTGTCGCGAAATGTTAATATAAACATAACTCAGGACTCCTTACAATGGTATGATATCATTGTTCACTCTCGTGGCTTTGCTTTGGGCTTCCCTAGAAGGCCTCAATAAACCCATGACACTTTAGAGTATTCCTCACTTATAAACCATTTTTCCGAAACCCTCGAACAAAGTACACCCTTTGTTCGACACTTTAGTCACTTTGGACTATACCTTCGAGGCTCACAATTCTTTGTTCGATATTTGAGGATTCTATTGACATGGCTTGGCTAAGTTTAGCTTCGAGGCTCACAATTCTTTGTTCGATATTCGAGGATTCTATTGACATGGCTCACAATTCTTTGTTTGATATTTGAGGATTCTATCGACGTAGCTAAGTTTAGGGCATGACTTTGATACCATGTTAGGAATCACGGATCTCCACAATGGTATGATATTGTCCACTTTGAGCATAAGCTCTCATGGCTTTGCTTTGGGCTTCTCCCGAAGGCTTCGTACCAATGGAGATAGTATTCCTCACTTATAAATTCATTATCTTCCACTAAATTAACAAACTGGGCTTCCTCCGAAGGCTTCGTTCCAATGGAGATAGTATTTCTCACTTATAAACCCATTATCTTCCACTAAATTAACGAACTTGGGATTCACTCCTAATAATCCTCAACACCACACTGGGTAAACCCTCGGTAAAAGAGTGCTTTCTTCTTACGATCTCCTTATCAGATCAGCTTCTCCTTCTTCTTTCACTACTTGAGCGTTGTTATTTCTGTAAGTTTGTTCTCCATTTTTGAAGTTCTTAGCTTCTTCCAATTGCCAATTTGTGAATGATTTTCTTTGGGATTACCTACTTGTATTATGGATCATGAAACACTGCCCGGAAATTTCCGTTCCATCAAAATTGGGCTCTGATTACGCGGGCTAGTTAGGGTTCGAGATGAATTATTGAGAGAAGTATTCAACGGCCGCATTGCGGTGGTCGTTTTCAAATTCCATACTTTCTTGCGTTGCGGATATTGGACATTGCGTAATGCCCACCAACTGTTCGATGAAATTCCTCTATGAAATGGTATATTTTACTTCTTCATCCGTCTTCATTTCCCCTCAATGTGGCTGTCACTTTCCAAAATTCTGCTATTTTCGTGTGACAAATATTGATCATTGGATATTGCCCACCGAATGTTCGATGAAATTCTATTATAAATTGGTATAATTGTACATATTCTCCCTTCTTCATTCCCTCTCAATGTGGCTGTCGCTTCCAAATTTATACTCCTTTCTGATGATGAACATTGAACATTGCATAGTGCCCACCAATTGTTTGGCTAATAAGTGGTATGCTCTTACATGTTCATCCTTCTTTGCTCCCCCACACATAAAAGGAAAAAAGTAATCCATTGAGAATTGAAATTTGTGGTTTTAGATTCAAAAGGTAGCTGTTTTTCTGATGATGAACATTGAACATTGAACATTGAATACTGCCTACCAATTGTTTGACTAATAAGTGGTATGCTCTTACATGTTCATCCTTCAAAATGTAATCCACTGAGAATTGAAATTTGTGGTTTTAGATTCAAAGGGTAGCTGTTTTTCTGTTTGGTATATCAATTTTTCTCTAGAACCTTTGATTTTGTAAGTACTAGTTATGATGTCAGATCTGTACAATGAAGAAAGGCTTGCACCCTCAAATGCAATGGATATCATAATGTCACTCAGAGTGGCAAATTGATGCATGTCAATGATGACCAAGGTACACCTTGTTGGTAAAGTCTACCACTTCAGAGCCAAGCGTCGACCGACTGAAAATGCTGGGCAAGCTGCCAAGTTCAAATGACGTTACGAGATGCAGCTCAAGGATCAACTATTTCCTTGGATCATTATGGATTCGTTTCGATAACATGACCTTGTGAATATTAGGAATTCAAAGTACCTTCTACTCAATGGAGTTTATCCCTTTTCATAGTCTATTCATAGTCTAGTGTTTTATAGGAAACTGAGTTCTTTCCTATATTGACTTTGATGTGCTTTTACCTTTACTATGCAGCTCAAGTTTCAACTGTTATGGATTTGTTTCGATAACATGGCCTTGTGAGTATTAGGAATTTAAAGTTCCCTTCTACCCGACGGAGTTCATCCCATTTCATAGTCTAGCATTCTATAGAAACTGAGTTATTTCTTATATTGGCTTTGATATGCTTTTACCTTTACTATGCAGCTCGAGGATCAACTGTTTCATTGGATCATTATGGATTCGTTTCGATAACATGACCTTGTGAGTATTATGAATTTAAAGTTCCCTTCTACTTAATGGAATTCGTCCCTTT

mRNA sequence

ATGTTCTTGGATCAGCTCGAGGTTCCTCGTTCCGTGGATAGTTTGAGTTTACTGATTTTTTTCCCTCAATTTTCAGGTGCTGTCCAATGTGCTCAGTGTCAAGGAACAGGAGTGAATTCAGAGGATCACTTCAATGGACGGTTTAAAGCTGGTGGCTTATGCTGGTTGTGCAGAATTAACGATACTGAGGGTACCGTGATGAACATTGCAGAGGCAAAAGGGACATCCTGTGTGGTGGCTGTAATGGAGCAGCTCAAGTTTCAACTGTTATGGATTTGTTTCGATAACATGGCCTTCTCGAGGATCAACTGTTTCATTGGATCATTATGGATTCGTTTCGATAACATGACCTTGTGAGTATTATGAATTTAAAGTTCCCTTCTACTTAATGGAATTCGTCCCTTT

Coding sequence (CDS)

ATGTTCTTGGATCAGCTCGAGGTTCCTCGTTCCGTGGATAGTTTGAGTTTACTGATTTTTTTCCCTCAATTTTCAGGTGCTGTCCAATGTGCTCAGTGTCAAGGAACAGGAGTGAATTCAGAGGATCACTTCAATGGACGGTTTAAAGCTGGTGGCTTATGCTGGTTGTGCAGAATTAACGATACTGAGGGTACCGTGATGAACATTGCAGAGGCAAAAGGGACATCCTGTGTGGTGGCTGTAATGGAGCAGCTCAAGTTTCAACTGTTATGGATTTGTTTCGATAACATGGCCTTCTCGAGGATCAACTGTTTCATTGGATCATTATGGATTCGTTTCGATAACATGACCTTGTGA

Protein sequence

MFLDQLEVPRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCRINDTEGTVMNIAEAKGTSCVVAVMEQLKFQLLWICFDNMAFSRINCFIGSLWIRFDNMTL

Homology

[Close]

BLAST of Carg17502 vs. NCBI nr
Match: KAG7021244.1 (hypothetical protein SDJN02_17932, partial [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 250.0 bits (637), Expect = 1.0e-62
Identity = 118/118 (100.00%), Postives = 118/118 (100.00%), Query Frame = 0


Query: 1   MFLDQLEVPRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCRIN 60
           MFLDQLEVPRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCRIN
Sbjct: 1   MFLDQLEVPRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCRIN 60

Query: 61  DTEGTVMNIAEAKGTSCVVAVMEQLKFQLLWICFDNMAFSRINCFIGSLWIRFDNMTL 119
           DTEGTVMNIAEAKGTSCVVAVMEQLKFQLLWICFDNMAFSRINCFIGSLWIRFDNMTL
Sbjct: 61  DTEGTVMNIAEAKGTSCVVAVMEQLKFQLLWICFDNMAFSRINCFIGSLWIRFDNMTL 118

[Close]

BLAST of Carg17502 vs. NCBI nr
Match: XP_023537582.1 (uncharacterized protein LOC111798573 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 80.5 bits (197), Expect = 1.1e-11
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. NCBI nr
Match: XP_022938233.1 (uncharacterized protein LOC111444376 [Cucurbita moschata])

HSP 1 Score: 80.5 bits (197), Expect = 1.1e-11
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. NCBI nr
Match: KAG6586393.1 (Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 80.5 bits (197), Expect = 1.1e-11
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. NCBI nr
Match: XP_022965999.1 (uncharacterized protein LOC111465718 [Cucurbita maxima])

HSP 1 Score: 80.5 bits (197), Expect = 1.1e-11
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. ExPASy Swiss-Prot
Match: Q9SN73 (Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=BSD2 PE=1 SV=1)

HSP 1 Score: 63.2 bits (152), Expect = 2.3e-09
Identity = 27/50 (54.00%), Postives = 33/50 (66.00%), Query Frame = 0


Query: 9   PRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           P+     SL+    +  G V C+QC+G GVN  DHFNG+FKAG LCWLCR
Sbjct: 62  PQGTKPNSLVCANCEGEGCVACSQCKGGGVNLIDHFNGQFKAGALCWLCR 111

[Close]

BLAST of Carg17502 vs. ExPASy Swiss-Prot
Match: Q9XF14 (Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic OS=Zea mays OX=4577 GN=BSD2 PE=2 SV=1)

HSP 1 Score: 61.6 bits (148), Expect = 6.8e-09
Identity = 23/34 (67.65%), Postives = 28/34 (82.35%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GA+ C +C+G GVNS D+F GRFKAG LCWLCR
Sbjct: 68  NGAIVCTKCEGNGVNSVDYFEGRFKAGSLCWLCR 101

[Close]

BLAST of Carg17502 vs. ExPASy TrEMBL
Match: A0A6J1HSG2 (uncharacterized protein LOC111465718 OS=Cucurbita maxima OX=3661 GN=LOC111465718 PE=4 SV=1)

HSP 1 Score: 80.5 bits (197), Expect = 5.2e-12
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. ExPASy TrEMBL
Match: A0A6J1FIB2 (uncharacterized protein LOC111444376 OS=Cucurbita moschata OX=3662 GN=LOC111444376 PE=4 SV=1)

HSP 1 Score: 80.5 bits (197), Expect = 5.2e-12
Identity = 33/34 (97.06%), Postives = 34/34 (100.00%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. ExPASy TrEMBL
Match: A0A6A5NU30 (Uncharacterized protein OS=Lupinus albus OX=3870 GN=Lal_00041045 PE=4 SV=1)

HSP 1 Score: 79.3 bits (194), Expect = 1.2e-11
Identity = 32/43 (74.42%), Postives = 35/43 (81.40%), Query Frame = 0


Query: 16  SLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           SL   F Q  GA+ C QC+GTG+NSEDHFNGRFKAGGLCWLCR
Sbjct: 84  SLCYMFSQLPGAILCTQCKGTGINSEDHFNGRFKAGGLCWLCR 126

[Close]

BLAST of Carg17502 vs. ExPASy TrEMBL
Match: A0A1U8DYJ8 (uncharacterized protein LOC107840731 OS=Capsicum annuum OX=4072 GN=LOC107840731 PE=4 SV=1)

HSP 1 Score: 76.6 bits (187), Expect = 7.5e-11
Identity = 32/39 (82.05%), Postives = 34/39 (87.18%), Query Frame = 0


Query: 20 FFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
          F P  +GAV CAQC+GTGVNS DHFNGRFKAGGLCWLCR
Sbjct: 3  FNPHGNGAVACAQCKGTGVNSVDHFNGRFKAGGLCWLCR 41

[Close]

BLAST of Carg17502 vs. ExPASy TrEMBL
Match: A0A6J1CMI1 (uncharacterized protein LOC111012989 OS=Momordica charantia OX=3673 GN=LOC111012989 PE=4 SV=1)

HSP 1 Score: 75.9 bits (185), Expect = 1.3e-10
Identity = 30/34 (88.24%), Postives = 33/34 (97.06%), Query Frame = 0


Query: 25  SGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           +GAV C+QC+GTGVNSEDHFNGRFKAGGLCWLCR
Sbjct: 80  NGAVNCSQCKGTGVNSEDHFNGRFKAGGLCWLCR 113

[Close]

BLAST of Carg17502 vs. TAIR 10
Match: AT3G47650.1 (DnaJ/Hsp40 cysteine-rich domain superfamily protein )

HSP 1 Score: 63.2 bits (152), Expect = 1.7e-10
Identity = 27/50 (54.00%), Postives = 33/50 (66.00%), Query Frame = 0


Query: 9   PRSVDSLSLLIFFPQFSGAVQCAQCQGTGVNSEDHFNGRFKAGGLCWLCR 59
           P+     SL+    +  G V C+QC+G GVN  DHFNG+FKAG LCWLCR
Sbjct: 62  PQGTKPNSLVCANCEGEGCVACSQCKGGGVNLIDHFNGQFKAGALCWLCR 111

The following BLAST results are available for this feature:

BLAST of Carg17502 vs. NCBI nr


Match Name	E-value	Identity	Description
KAG7021244.1	1.0e-62	100.00	hypothetical protein SDJN02_17932, partial [Cucurbita argyrosperma subsp. argyro...	[more]
XP_023537582.1	1.1e-11	97.06	uncharacterized protein LOC111798573 [Cucurbita pepo subsp. pepo]	[more]
XP_022938233.1	1.1e-11	97.06	uncharacterized protein LOC111444376 [Cucurbita moschata]	[more]
KAG6586393.1	1.1e-11	97.06	Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic, partial [Cucurbita argyrosperm...	[more]
XP_022965999.1	1.1e-11	97.06	uncharacterized protein LOC111465718 [Cucurbita maxima]	[more]

BLAST of Carg17502 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9SN73	2.3e-09	54.00	Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic OS=Arabidopsis thaliana OX=3702...	[more]
Q9XF14	6.8e-09	67.65	Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic OS=Zea mays OX=4577 GN=BSD2 PE=...	[more]

BLAST of Carg17502 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1HSG2	5.2e-12	97.06	uncharacterized protein LOC111465718 OS=Cucurbita maxima OX=3661 GN=LOC111465718...	[more]
A0A6J1FIB2	5.2e-12	97.06	uncharacterized protein LOC111444376 OS=Cucurbita moschata OX=3662 GN=LOC1114443...	[more]
A0A6A5NU30	1.2e-11	74.42	Uncharacterized protein OS=Lupinus albus OX=3870 GN=Lal_00041045 PE=4 SV=1	[more]
A0A1U8DYJ8	7.5e-11	82.05	uncharacterized protein LOC107840731 OS=Capsicum annuum OX=4072 GN=LOC107840731 ...	[more]
A0A6J1CMI1	1.3e-10	88.24	uncharacterized protein LOC111012989 OS=Momordica charantia OX=3673 GN=LOC111012...	[more]

BLAST of Carg17502 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G47650.1	1.7e-10	54.00	DnaJ/Hsp40 cysteine-rich domain superfamily protein	[more]

InterPro

Analysis Name: InterPro Annotations of Silver-seed gourd (SMH-JMG-627) v2
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR15852:SF51	PROTEIN BUNDLE SHEATH DEFECTIVE 2, CHLOROPLASTIC	coord: 25..60
None	No IPR available	PANTHER	PTHR15852	PLASTID TRANSCRIPTIONALLY ACTIVE PROTEIN	coord: 25..60

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Carg17502-RA	Carg17502-RA	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0061077	chaperone-mediated protein folding
biological_process	GO:0110102	ribulose bisphosphate carboxylase complex assembly
cellular_component	GO:0101031	chaperone complex
cellular_component	GO:0009570	chloroplast stroma
molecular_function	GO:1905538	polysome binding
molecular_function	GO:0044183	protein folding chaperone