Sgr022643 (gene) Monk fruit (Qingpiguo) v1

Overview


Name	Sgr022643
Type	gene
Organism	Siraitia grosvenorii (Monk fruit (Qingpiguo) v1)
Description	hippocampus abundant transcript-like protein 1
Location	tig00000289: 1888450 .. 1890639 (+)
RNA-Seq Expression	Sgr022643
Synteny	Sgr022643

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGTGGTTCTTCCATTGCTTGGTCAGCTGGCAGACGAGTATGGTCGAAAACCTTTACTACTTCTTACAATATCAACAAGCATATTTCCTTTTGGTATGTTTCCATTTTCATGTTCTTCATGTTCTAAAATTCATATGAGCAGATGAATTTTTTTTTTCCAAATTTTACAGTTCTTTTTTTATGCATTTTGGTTTCAGCCTTATTTGTGTGGGATCAATCCAAGGGTTATGTATATGCTTACTATGTGCTTCGTACAATATCAAAGATACTGAGTCAAGGCAGCATATTCTTCATTTCTGTTGCATATGCTGTAAGGATTATGTCTTTTATTTTCTTTCGGCCCAGTTTGATAACGTTCTCACTAGGCCCTATTGATAACCATTTTGTTTTTAGTTTTCTGTTTTTGAAAATTAAGCTTATAAACACTACTTCTACCTATGTGTTTATTTGTTTTGTTGTCACTTTTTAAAATTTGGCTAAGAATTCAAATGTGTTTTTAAGAAATGTTAAAAACATACCAAAGAAATTGTAAGGAATGAAGCATAATTTTTAAAACAGAAAACTAAAAATGAAATTGTTATCAAACAAGACCTTATTTTTCTGTCTTAAAATTTTAAACTTGTTTACAAACAATTCTTTTGTTTTGTTTCCTACATTTAAGAATGATTTTGAAATCATGGCCAAACTTGAAAAACAAAGAACAGAAGTTTTGGAAACTATTCTTTTTAGTTTTAAAAATGTATTTATAGTAAACAAGCTTAATTTTTTAAAACAGAAAATTAAACCATCATGGTCTTAACCTTTTGTTTTCAAGGAAAAATTTCAGATTAAGCAATCTCTTTAGCTTTTCCATCTTGTAGGCGGATCTTGTACATGAAAGTAGGAGAGCTGCAGTGTTTGGCTGGATCACTGGCCTTTGTTCTGCTTCTCATGTTGTTGGAAATTTGCTAGCACGGTTTCTTCCCGAAAAGTACATTTTCTCGGTACTAACTTCCTGCTCAGTAGCATCATGGATTTAACTCTCAACATTTCATTTTCCATTTATCACATCAGGAATTTGCTTCTCTGTTTCAGGTCTCCATAGTTTTATTGATCTTCTGTCCCATCTACATGTATTTCTTCCTGGCTGAGACTGTAAAATTAGCACCAAAAAGCGATGAAGAACCTGGTTGCTTGTCAAAGATGATCAACGTTCTCAACAGACGATCAAAACTATGAGAGATGCAGCGGATATAGTCATCAATAGGTATTTTTTTCTAGCTTATTTACTTTTTCTTCATGTTGCAAAATGTCATCAAACTTTCTTTTCTATTGAGAACAAGCATCGTTTCTTCATGTCCATTGTTGAAGAGCTCCATTCTGTTTTGCAGTCCAACACTTAGAAGCATATCTTATGTTTCTTTCTTCCTAGAGTTGGGAATGTCTGGCATCACTAGTGTCCTAATGGTAAGTTTAGATGAAGAAAATGTATATCGTATCGATTAAAAGCATTTGTTTGATGAACCCACGGCAAAGATAGAATCCAACAATGTAATTGAGTTAGATTTTGATCTTTTTTATGATATCATTAACTAATAATTTGAAAGTTCTGCAGTTCTATTTGAAGGCAGCTTTTGGCTTTGACAAAAACCAAAACTCAGAAATCTTGATGCTCGTGGGAATAGGCTCAATTTTCACTCAGGTATATTCCTTTCCAACAAGAACTGAAAAAGAAGTCCTTTTCTGTAATAGACTCAATCAAATCCAACTACTCAATAGACAACAAATACAAATAACATCAGTCTCTGAGTCTCCATAGTTTTCTTCCACCTAAACTTTGACACCATTACGAAAATCGTCACCCTCATATCAGTTAAGAAACTGTTCAAATTTGCTATCCATTTTATTCAGTGCGTTGAAGTTGATAATTTGCTTCCAGATGTTGGTGCTTCCACTGATAAATCCACTGATCGGGGAGGAAGCTATATTATGCATGGCCATACTTGCATCGATAGCTTACGTGAGTCGTTTCAAATCACATTTCTAGCATCCCCTTTATCCGTTAAGTTGCTTCTGTCAGCCCCAACCTCAAGAAAACAAAAATATGAAGGGTTGGGAAGCTTCTTAAGAAAAGGAATACAGTCCTGATAGTTTTCCTTTTCCTTTTGGCTGTACAGGCATTGTTCTATGGCTTGGCATGGGCAGCTTGG

mRNA sequence

ATGGTGGTTCTTCCATTGCTTGGTCAGCTGGCAGACGAGTATGGTCGAAAACCTTTACTACTTCTTACAATATCAACAAGCATATTTCCTTTTGCCTTATTTGTGTGGGATCAATCCAAGGGTTATGTATATGCTTACTATGTGCTTCGTACAATATCAAAGATACTGAGTCAAGGCAGCATATTCTTCATTTCTGTTGCATATGCTGCGGATCTTGTACATGAAAGTAGGAGAGCTGCAGTGTTTGGCTGGATCACTGGCCTTTGTTCTGCTTCTCATGTTGTTGGAAATTTGCTAGCACGGTTTCTTCCCGAAAATCCAACACTTAGAAGCATATCTTATGTTTCTTTCTTCCTAGAGTTGGGAATGTCTGGCATCACTAGTGTCCTAATGTTCTATTTGAAGGCAGCTTTTGGCTTTGACAAAAACCAAAACTCAGAAATCTTGATGCTCGTGGGAATAGGCTCAATTTTCACTCAGATGTTGGTGCTTCCACTGATAAATCCACTGATCGGGGAGGAAGCTATATTATGCATGGCCATACTTGCATCGATAGCTTACGCATTGTTCTATGGCTTGGCATGGGCAGCTTGG

Coding sequence (CDS)

ATGGTGGTTCTTCCATTGCTTGGTCAGCTGGCAGACGAGTATGGTCGAAAACCTTTACTACTTCTTACAATATCAACAAGCATATTTCCTTTTGCCTTATTTGTGTGGGATCAATCCAAGGGTTATGTATATGCTTACTATGTGCTTCGTACAATATCAAAGATACTGAGTCAAGGCAGCATATTCTTCATTTCTGTTGCATATGCTGCGGATCTTGTACATGAAAGTAGGAGAGCTGCAGTGTTTGGCTGGATCACTGGCCTTTGTTCTGCTTCTCATGTTGTTGGAAATTTGCTAGCACGGTTTCTTCCCGAAAATCCAACACTTAGAAGCATATCTTATGTTTCTTTCTTCCTAGAGTTGGGAATGTCTGGCATCACTAGTGTCCTAATGTTCTATTTGAAGGCAGCTTTTGGCTTTGACAAAAACCAAAACTCAGAAATCTTGATGCTCGTGGGAATAGGCTCAATTTTCACTCAGATGTTGGTGCTTCCACTGATAAATCCACTGATCGGGGAGGAAGCTATATTATGCATGGCCATACTTGCATCGATAGCTTACGCATTGTTCTATGGCTTGGCATGGGCAGCTTGG

Protein sequence

MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPENPTLRSISYVSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILCMAILASIAYALFYGLAWAAW

Homology

[Close]

BLAST of Sgr022643 vs. NCBI nr
Match: XP_022133709.1 (hippocampus abundant transcript-like protein 1 [Momordica charantia])

HSP 1 Score: 344.4 bits (882), Expect = 6.7e-91
Identity = 193/260 (74.23%), Postives = 197/260 (75.77%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISV+YAAD+VHESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVSYAADIVHESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFSVSVVLLIFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          +PTLRSISYVSFF
Sbjct: 191 VYMYFFLVETVELVPKGDGEPGCLSKTINVLNKRFRTMRDAAYIVIHSPTLRSISYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIF+QMLVLPLINPLIGEEAILC
Sbjct: 251 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFSQMLVLPLINPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. NCBI nr
Match: XP_008456592.1 (PREDICTED: hippocampus abundant transcript-like protein 1 [Cucumis melo] >TYK11756.1 hippocampus abundant transcript-like protein 1 [Cucumis melo var. makuwa])

HSP 1 Score: 336.7 bits (862), Expect = 1.4e-88
Identity = 186/260 (71.54%), Postives = 195/260 (75.00%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLT+STSIFPFAL VWDQSKGY+YAYYVLRTISKILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTVSTSIFPFALLVWDQSKGYIYAYYVLRTISKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAAD+V ESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVAYAADIVQESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFVVSIVLLMFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 191 IYMYFFLHETVKPILKNDGEPNWLSKTVNVLNRRFRTMRDATEIVIDNPTLRSITYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVGIGSIFTQMLVLPL+NPLIGEEAILC
Sbjct: 251 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGIGSIFTQMLVLPLLNPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. NCBI nr
Match: KAG7016339.1 (Hippocampus abundant transcript-like protein 1 [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 334.0 bits (855), Expect = 9.1e-88
Identity = 185/260 (71.15%), Postives = 193/260 (74.23%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPF + VWDQSK Y+YAYYVLRTI+KILSQGS
Sbjct: 40  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFGVLVWDQSKAYIYAYYVLRTIAKILSQGS 99

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 100 IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFLVSIVLLIFCP 159

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 160 IYMYFFLDETVQRVPKSDGEPGCLSKTVDVLNRRFGTMRDAAGIVLDNPTLRSITYVSFF 219

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVG GSIFTQMLVLPLINPLIGEEAILC
Sbjct: 220 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGFGSIFTQMLVLPLINPLIGEEAILC 279

[Close]

BLAST of Sgr022643 vs. NCBI nr
Match: KAG6578815.1 (Hippocampus abundant transcript-like protein 1, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 332.8 bits (852), Expect = 2.0e-87
Identity = 184/260 (70.77%), Postives = 193/260 (74.23%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPF + VWDQSK Y+YAYYVLRTI+KILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFGVLVWDQSKAYIYAYYVLRTIAKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP---------------- 120
           IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP                
Sbjct: 131 IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPVKYIFLVSIVLLIFCP 190

Query: 121 ----------------------------------------------ENPTLRSISYVSFF 180
                                                         +NPTLRSI+YVSFF
Sbjct: 191 IYMYFFLDETVQRVPKSDGEPGCLSKTVDILNRRFGTMRDAAGIVLDNPTLRSITYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVG GSIFTQMLVLPLINPLIGEEAILC
Sbjct: 251 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGFGSIFTQMLVLPLINPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. NCBI nr
Match: XP_023550904.1 (hippocampus abundant transcript-like protein 1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 332.8 bits (852), Expect = 2.0e-87
Identity = 184/260 (70.77%), Postives = 193/260 (74.23%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPF + VWDQSK Y+YAYYVLRTI+KILSQGS
Sbjct: 88  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFGVLVWDQSKAYIYAYYVLRTIAKILSQGS 147

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAADLVHE+RRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 148 IFFISVAYAADLVHENRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFLVSIVLLIFCP 207

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 208 IYMYFFLDETVERVPKSDGEPGCLSKTVDVLNRRFGTMRDAAGIVLDNPTLRSITYVSFF 267

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVG GSIFTQMLVLPLINPLIGEEAILC
Sbjct: 268 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGFGSIFTQMLVLPLINPLIGEEAILC 327

[Close]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot
Match: Q8CIA9 (Hippocampus abundant transcript-like protein 1 OS=Mus musculus OX=10090 GN=Mfsd14b PE=2 SV=3)

HSP 1 Score: 53.1 bits (126), Expect = 4.1e-06
Identity = 32/102 (31.37%), Postives = 52/102 (50.98%), Query Frame = 0


Query: 5   PLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFI 64
           PL+G L+D +GRKP LL T+  + FP  L      +   + Y+ + ++S + S    F +
Sbjct: 100 PLIGALSDVWGRKPFLLGTVFFTCFPIPLM-----RINPWWYFGMISVSGVFS--VTFSV 159

Query: 65  SVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPEN 107
             AY AD   E  R+  +GW++   +AS V    +  +L  N
Sbjct: 160 IFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSAN 194

[Close]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot
Match: P02982 (Tetracycline resistance protein, class A OS=Escherichia coli OX=562 GN=tetA PE=3 SV=2)

HSP 1 Score: 48.9 bits (115), Expect = 7.7e-05
Identity = 30/107 (28.04%), Postives = 58/107 (54.21%), Query Frame = 0


Query: 5   PLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFI 64
           P+LG L+D +GR+P+LL++++ +   +A+     +  +++  Y+ R ++ I   G+   +
Sbjct: 61  PVLGALSDRFGRRPVLLVSLAGAAVDYAIMA---TAPFLWVLYIGRIVAGI--TGATGAV 120

Query: 65  SVAYAADLVHESRRAAVFGWITGLCS----ASHVVGNLLARFLPENP 108
           + AY AD+     RA  FG+++        A  V+G L+  F P  P
Sbjct: 121 AGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP 162

[Close]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot
Match: Q5SR56 (Hippocampus abundant transcript-like protein 1 OS=Homo sapiens OX=9606 GN=MFSD14B PE=1 SV=3)

HSP 1 Score: 47.4 bits (111), Expect = 2.2e-04
Identity = 56/253 (22.13%), Postives = 98/253 (38.74%), Query Frame = 0


Query: 5   PLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFI 64
           PL+G L+D +GRKP LL T+  + FP  L      +   + Y+ + ++S + S    F +
Sbjct: 98  PLIGALSDVWGRKPFLLGTVFFTCFPIPLM-----RISPWWYFAMISVSGVFS--VTFSV 157

Query: 65  SVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFL--------------------- 124
             AY AD+  E  R+  +GW++   +AS V    +  +L                     
Sbjct: 158 IFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDI 217

Query: 125 -------PEN--PTLRSISY----------------------------VSFFLE-LGMSG 184
                  PE+    +R +S+                            ++ FL  L  +G
Sbjct: 218 CFILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAG 277

Query: 185 ITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILCMAILASI 199
             S    YL+   GF   + +  + +VGI SI  Q   L ++   +G +  + + +   +
Sbjct: 278 QYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQM 337

[Close]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot
Match: A4IF94 (Hippocampus abundant transcript-like protein 1 OS=Bos taurus OX=9913 GN=MFSD14B PE=2 SV=1)

HSP 1 Score: 46.6 bits (109), Expect = 3.8e-04
Identity = 56/253 (22.13%), Postives = 93/253 (36.76%), Query Frame = 0


Query: 5   PLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFI 64
           PL+G L+D +GRKP LL T+  + FP  L      +   + Y+ + +IS + S    F +
Sbjct: 95  PLIGALSDVWGRKPFLLGTVFFTCFPIPLM-----RISPWWYFAMISISGVFS--VTFSV 154

Query: 65  SVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARF---------------------- 124
             AY AD+  E  R+  +GW++   +AS V    +  +                      
Sbjct: 155 IFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDI 214

Query: 125 ----------LPE---------------------------NPTLRSISYVSFFLELGMSG 184
                     LPE                           + T+  I    F   L  +G
Sbjct: 215 CFILLAVPESLPEKMRPLSWGARISWKQADPFASLKKVGKDSTILLICITVFLSYLPEAG 274

Query: 185 ITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILCMAILASI 199
             S    YL+   GF   + +  + +VGI SI  Q + L  +   +G +  + + +   +
Sbjct: 275 QYSSFFLYLRQVIGFGSIKIAAFIAMVGILSIVAQTVFLTSLMRSLGNKNTVLLGLGFQM 334

[Close]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot
Match: B2RYH9 (Hippocampus abundant transcript-like protein 1 OS=Rattus norvegicus OX=10116 GN=Mfsd14b PE=2 SV=1)

HSP 1 Score: 46.2 bits (108), Expect = 5.0e-04
Identity = 55/253 (21.74%), Postives = 89/253 (35.18%), Query Frame = 0


Query: 5   PLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGSIFFI 64
           PL+G L+D +GRKP LL T+  + FP  L      +   + Y+ + ++S + S    F +
Sbjct: 100 PLIGALSDVWGRKPFLLGTVFFTCFPIPLM-----RISPWWYFGMISVSGVFS--VTFSV 159

Query: 65  SVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPEN------------------ 124
             AY AD   E  R+  +GW++   +AS V    +  +L  N                  
Sbjct: 160 IFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSSNYGDSLVVLVATVVALLDI 219

Query: 125 -----------------------------------------PTLRSISYVSFFLELGMSG 184
                                                     T+  I    F   L  +G
Sbjct: 220 CFILVAVPESLPEKIRPASWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAG 279

Query: 185 ITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILCMAILASI 199
             S    YL+   GF   +    + +VGI SI  Q + L  +   +G +  + + +   I
Sbjct: 280 QYSSFFLYLRQVIGFGSVKIVAFIAMVGILSILAQTVFLSKLMRSLGNKNTVLLGLGFQI 339

[Close]

BLAST of Sgr022643 vs. ExPASy TrEMBL
Match: A0A6J1BWS3 (hippocampus abundant transcript-like protein 1 OS=Momordica charantia OX=3673 GN=LOC111006226 PE=4 SV=1)

HSP 1 Score: 344.4 bits (882), Expect = 3.3e-91
Identity = 193/260 (74.23%), Postives = 197/260 (75.77%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISV+YAAD+VHESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVSYAADIVHESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFSVSVVLLIFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          +PTLRSISYVSFF
Sbjct: 191 VYMYFFLVETVELVPKGDGEPGCLSKTINVLNKRFRTMRDAAYIVIHSPTLRSISYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIF+QMLVLPLINPLIGEEAILC
Sbjct: 251 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFSQMLVLPLINPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. ExPASy TrEMBL
Match: A0A5D3CMV5 (Hippocampus abundant transcript-like protein 1 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold304G00750 PE=4 SV=1)

HSP 1 Score: 336.7 bits (862), Expect = 6.8e-89
Identity = 186/260 (71.54%), Postives = 195/260 (75.00%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLT+STSIFPFAL VWDQSKGY+YAYYVLRTISKILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTVSTSIFPFALLVWDQSKGYIYAYYVLRTISKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAAD+V ESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVAYAADIVQESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFVVSIVLLMFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 191 IYMYFFLHETVKPILKNDGEPNWLSKTVNVLNRRFRTMRDATEIVIDNPTLRSITYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVGIGSIFTQMLVLPL+NPLIGEEAILC
Sbjct: 251 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGIGSIFTQMLVLPLLNPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. ExPASy TrEMBL
Match: A0A1S3C4V7 (hippocampus abundant transcript-like protein 1 OS=Cucumis melo OX=3656 GN=LOC103496503 PE=4 SV=1)

HSP 1 Score: 336.7 bits (862), Expect = 6.8e-89
Identity = 186/260 (71.54%), Postives = 195/260 (75.00%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLT+STSIFPFAL VWDQSKGY+YAYYVLRTISKILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTVSTSIFPFALLVWDQSKGYIYAYYVLRTISKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAAD+V ESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVAYAADIVQESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFVVSIVLLMFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 191 IYMYFFLHETVKPILKNDGEPNWLSKTVNVLNRRFRTMRDATEIVIDNPTLRSITYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVGIGSIFTQMLVLPL+NPLIGEEAILC
Sbjct: 251 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGIGSIFTQMLVLPLLNPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. ExPASy TrEMBL
Match: A0A6J1JTZ7 (hippocampus abundant transcript-like protein 1 OS=Cucurbita maxima OX=3661 GN=LOC111488893 PE=4 SV=1)

HSP 1 Score: 332.8 bits (852), Expect = 9.8e-88
Identity = 184/260 (70.77%), Postives = 193/260 (74.23%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPF + VWDQS+ Y+YAYYVLRTI+KILSQGS
Sbjct: 88  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFGVLVWDQSRAYIYAYYVLRTIAKILSQGS 147

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 148 IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFLVSIVLLIFCP 207

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 208 IYMYFFVDETVKRVPKSDEEPGCLSKTVDVLNRRFGTMRDAAGIVLDNPTLRSITYVSFF 267

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVG GSIFTQMLVLPLINPLIGEEAILC
Sbjct: 268 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGFGSIFTQMLVLPLINPLIGEEAILC 327

[Close]

BLAST of Sgr022643 vs. ExPASy TrEMBL
Match: A0A6J1FK37 (hippocampus abundant transcript-like protein 1 OS=Cucurbita moschata OX=3662 GN=LOC111444754 PE=4 SV=1)

HSP 1 Score: 332.8 bits (852), Expect = 9.8e-88
Identity = 185/260 (71.15%), Postives = 192/260 (73.85%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MVVLPLLGQLADEYGRKPLLLLTISTSIFPF + VWDQSK Y+YAYYVLRTI+KILSQGS
Sbjct: 71  MVVLPLLGQLADEYGRKPLLLLTISTSIFPFGVLVWDQSKAYIYAYYVLRTIAKILSQGS 130

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE--------------- 120
           IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPE               
Sbjct: 131 IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLPEKYIFLVSIVLLIFCP 190

Query: 121 -----------------------------------------------NPTLRSISYVSFF 180
                                                          NPTLRSI+YVSFF
Sbjct: 191 IYMYFFLDETVQRVPKSDGEPGCLSKTVDVLNRRFGTMRDAAGIVLDNPTLRSITYVSFF 250

Query: 181 LELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLINPLIGEEAILC 199
           L+LGM+GITSVLMFYLKA FGFDKNQNSEILMLVG GSIFTQMLVLPLINPLIGEEAILC
Sbjct: 251 LKLGMTGITSVLMFYLKAVFGFDKNQNSEILMLVGFGSIFTQMLVLPLINPLIGEEAILC 310

[Close]

BLAST of Sgr022643 vs. TAIR 10
Match: AT2G16980.1 (Major facilitator superfamily protein )

HSP 1 Score: 94.0 bits (232), Expect = 1.5e-19
Identity = 74/284 (26.06%), Postives = 118/284 (41.55%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MV++P++G L+D YG K +L L +  S+ P A+  + +   + YA+YV++T+  ++ QG+
Sbjct: 65  MVMMPVIGNLSDRYGIKAMLTLPMCLSVLPPAILGYRRDTNFFYAFYVIKTLFDMVCQGT 124

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP---------------- 120
           I  ++ AY A  VH ++R ++FG + G+ S S V  +L ARFL                 
Sbjct: 125 IDCLANAYVAKNVHGTKRISMFGILAGVSSISGVCASLSARFLSIASTFQVAAISLFIGL 184

Query: 121 ----------------------------------------ENPTLRSIS----------- 180
                                                     P LR              
Sbjct: 185 VYMRVFLKERLQDADDDDEADSGGCRSHQEVHNGGDLKMLTEPILRDAPTKTHVFNSKYS 244

Query: 181 -------------------YVSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGI 199
                               V+FF     SG  S LM++LKA FGF+KN  +E+ +LV I
Sbjct: 245 SWKDMVSLINNSTILIQALVVTFFATFSESGRGSALMYFLKARFGFNKNDFAELFLLVTI 304

[Close]

BLAST of Sgr022643 vs. TAIR 10
Match: AT2G16980.2 (Major facilitator superfamily protein )

HSP 1 Score: 94.0 bits (232), Expect = 1.5e-19
Identity = 74/284 (26.06%), Postives = 118/284 (41.55%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           MV++P++G L+D YG K +L L +  S+ P A+  + +   + YA+YV++T+  ++ QG+
Sbjct: 65  MVMMPVIGNLSDRYGIKAMLTLPMCLSVLPPAILGYRRDTNFFYAFYVIKTLFDMVCQGT 124

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP---------------- 120
           I  ++ AY A  VH ++R ++FG + G+ S S V  +L ARFL                 
Sbjct: 125 IDCLANAYVAKNVHGTKRISMFGILAGVSSISGVCASLSARFLSIASTFQVAAISLFIGL 184

Query: 121 ----------------------------------------ENPTLRSIS----------- 180
                                                     P LR              
Sbjct: 185 VYMRVFLKERLQDADDDDEADSGGCRSHQEVHNGGDLKMLTEPILRDAPTKTHVFNSKYS 244

Query: 181 -------------------YVSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGI 199
                               V+FF     SG  S LM++LKA FGF+KN  +E+ +LV I
Sbjct: 245 SWKDMVSLINNSTILIQALVVTFFATFSESGRGSALMYFLKARFGFNKNDFAELFLLVTI 304

[Close]

BLAST of Sgr022643 vs. TAIR 10
Match: AT2G16990.1 (Major facilitator superfamily protein )

HSP 1 Score: 82.4 bits (202), Expect = 4.4e-16
Identity = 64/281 (22.78%), Postives = 114/281 (40.57%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           M+++P++G L+D YG K +L L +  SI P  +  + +   + Y +Y+ + ++ ++ +G+
Sbjct: 64  MIMMPVIGNLSDRYGIKTILTLPMCLSIVPPVILGYRRDIKFFYVFYISKILTSMVCEGT 123

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP---------------- 120
           +  ++ AY A  +H S R + FG + G+ + + + G L+ARFLP                
Sbjct: 124 VDCLAYAYVAVNIHGSTRISAFGILAGIKTIAGLFGTLVARFLPIALTFQVSAISFFVGL 183

Query: 121 --------------ENPTLRSISY------------------------------------ 180
                         E+  L   +Y                                    
Sbjct: 184 VYMRVFLKEKLNDDEDDDLHHGTYHQEDHDSINTTMLAEPILNDRPIKTQVFHKKYSSLK 243

Query: 181 -----------------VSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSI 199
                            V+FF     SG+ S  +++LKA FGFDK Q +++L+L+ I   
Sbjct: 244 DMISLMKTSTIFFQALVVTFFSSFSDSGMESAFLYFLKARFGFDKKQFADLLLLITIVGS 303

[Close]

BLAST of Sgr022643 vs. TAIR 10
Match: AT2G16990.2 (Major facilitator superfamily protein )

HSP 1 Score: 82.4 bits (202), Expect = 4.4e-16
Identity = 64/281 (22.78%), Postives = 114/281 (40.57%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYVLRTISKILSQGS 60
           M+++P++G L+D YG K +L L +  SI P  +  + +   + Y +Y+ + ++ ++ +G+
Sbjct: 64  MIMMPVIGNLSDRYGIKTILTLPMCLSIVPPVILGYRRDIKFFYVFYISKILTSMVCEGT 123

Query: 61  IFFISVAYAADLVHESRRAAVFGWITGLCSASHVVGNLLARFLP---------------- 120
           +  ++ AY A  +H S R + FG + G+ + + + G L+ARFLP                
Sbjct: 124 VDCLAYAYVAVNIHGSTRISAFGILAGIKTIAGLFGTLVARFLPIALTFQVSAISFFVGL 183

Query: 121 --------------ENPTLRSISY------------------------------------ 180
                         E+  L   +Y                                    
Sbjct: 184 VYMRVFLKEKLNDDEDDDLHHGTYHQEDHDSINTTMLAEPILNDRPIKTQVFHKKYSSLK 243

Query: 181 -----------------VSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSI 199
                            V+FF     SG+ S  +++LKA FGFDK Q +++L+L+ I   
Sbjct: 244 DMISLMKTSTIFFQALVVTFFSSFSDSGMESAFLYFLKARFGFDKKQFADLLLLITIVGS 303

[Close]

BLAST of Sgr022643 vs. TAIR 10
Match: AT2G16970.1 (Major facilitator superfamily protein )

HSP 1 Score: 67.4 bits (163), Expect = 1.5e-11
Identity = 67/270 (24.81%), Postives = 110/270 (40.74%), Query Frame = 0


Query: 1   MVVLPLLGQLADEYGRKPLLLLTISTSIFPFALFVWDQSKGYVYAYYV------------ 60
           MV++P++G L+D YG K LL L +  SI P A+  + +   + YA+Y+            
Sbjct: 65  MVMMPVIGNLSDRYGIKTLLTLPMCLSILPPAILAYRRDTNFFYAFYITKILFDMAKNVC 124

Query: 61  -------------LRTIS--------KILSQGSI-------FFISVAYAADLVHE----- 120
                        +R+IS        ++L   SI       FF  + Y    + E     
Sbjct: 125 GRKRISMFGVLAGVRSISGVCATFSARLLPIASIFQVAAISFFFGLVYMRVFLKERLHDD 184

Query: 121 ------------SRRAAVFGWITGLC--------SASHVVGNL-------LARFLPENPT 180
                        R     G +T L         +  H+V N        +   +  +  
Sbjct: 185 DEDDCDEDDNTSGRNHHDGGDLTMLAEPILRDAPTKIHIVLNTKYSSLKDMVSLIKNSTI 244

Query: 181 LRSISYVSFFLELGMSGITSVLMFYLKAAFGFDKNQNSEILMLVGIGSIFTQMLVLPLIN 199
           L     V+FF     SG+ S  +++LKA FGF+KN  +E+++LV I    +Q+ +LP + 
Sbjct: 245 LVQTLVVTFFATFAQSGMQSAFLYFLKARFGFNKNDFAELILLVTIIGSISQLFILPKLV 304

The following BLAST results are available for this feature:

BLAST of Sgr022643 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022133709.1	6.7e-91	74.23	hippocampus abundant transcript-like protein 1 [Momordica charantia]	[more]
XP_008456592.1	1.4e-88	71.54	PREDICTED: hippocampus abundant transcript-like protein 1 [Cucumis melo] >TYK117...	[more]
KAG7016339.1	9.1e-88	71.15	Hippocampus abundant transcript-like protein 1 [Cucurbita argyrosperma subsp. ar...	[more]
KAG6578815.1	2.0e-87	70.77	Hippocampus abundant transcript-like protein 1, partial [Cucurbita argyrosperma ...	[more]
XP_023550904.1	2.0e-87	70.77	hippocampus abundant transcript-like protein 1 [Cucurbita pepo subsp. pepo]	[more]

BLAST of Sgr022643 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q8CIA9	4.1e-06	31.37	Hippocampus abundant transcript-like protein 1 OS=Mus musculus OX=10090 GN=Mfsd1...	[more]
P02982	7.7e-05	28.04	Tetracycline resistance protein, class A OS=Escherichia coli OX=562 GN=tetA PE=3...	[more]
Q5SR56	2.2e-04	22.13	Hippocampus abundant transcript-like protein 1 OS=Homo sapiens OX=9606 GN=MFSD14...	[more]
A4IF94	3.8e-04	22.13	Hippocampus abundant transcript-like protein 1 OS=Bos taurus OX=9913 GN=MFSD14B ...	[more]
B2RYH9	5.0e-04	21.74	Hippocampus abundant transcript-like protein 1 OS=Rattus norvegicus OX=10116 GN=...	[more]

BLAST of Sgr022643 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1BWS3	3.3e-91	74.23	hippocampus abundant transcript-like protein 1 OS=Momordica charantia OX=3673 GN...	[more]
A0A5D3CMV5	6.8e-89	71.54	Hippocampus abundant transcript-like protein 1 OS=Cucumis melo var. makuwa OX=11...	[more]
A0A1S3C4V7	6.8e-89	71.54	hippocampus abundant transcript-like protein 1 OS=Cucumis melo OX=3656 GN=LOC103...	[more]
A0A6J1JTZ7	9.8e-88	70.77	hippocampus abundant transcript-like protein 1 OS=Cucurbita maxima OX=3661 GN=LO...	[more]
A0A6J1FK37	9.8e-88	71.15	hippocampus abundant transcript-like protein 1 OS=Cucurbita moschata OX=3662 GN=...	[more]

BLAST of Sgr022643 vs. TAIR 10


Match Name	E-value	Identity	Description
AT2G16980.1	1.5e-19	26.06	Major facilitator superfamily protein	[more]
AT2G16980.2	1.5e-19	26.06	Major facilitator superfamily protein	[more]
AT2G16990.1	4.4e-16	22.78	Major facilitator superfamily protein	[more]
AT2G16990.2	4.4e-16	22.78	Major facilitator superfamily protein	[more]
AT2G16970.1	1.5e-11	24.81	Major facilitator superfamily protein	[more]

InterPro

Analysis Name: InterPro Annotations of Monk fruit (Qingpiguo) v1
Date Performed: 2022-08-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036259	MFS transporter superfamily	GENE3D	1.20.1250.20	MFS general substrate transporter like domains	coord: 1..106 e-value: 3.6E-12 score: 47.7
IPR036259	MFS transporter superfamily	SUPERFAMILY	103473	MFS general substrate transporter	coord: 2..194
IPR011701	Major facilitator superfamily	PFAM	PF07690	MFS_1	coord: 2..116 e-value: 3.9E-10 score: 39.2
None	No IPR available	PANTHER	PTHR23504:SF108	HIPPOCAMPUS ABUNDANT TRANSCRIPT-LIKE PROTEIN 1	coord: 106..198
None	No IPR available	PANTHER	PTHR23504:SF108	HIPPOCAMPUS ABUNDANT TRANSCRIPT-LIKE PROTEIN 1	coord: 1..106
None	No IPR available	PANTHER	PTHR23504	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10	coord: 106..198 coord: 1..106
IPR005829	Sugar transporter, conserved site	PROSITE	PS00216	SUGAR_TRANSPORT_1	coord: 7..23

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Sgr022643.1	Sgr022643.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0055085	transmembrane transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0022857	transmembrane transporter activity