Sed0016936 (gene) Chayote v1

Overview


Name	Sed0016936
Type	gene
Organism	Sechium edule (Chayote v1)
Description	Serine protease inhibitor
Location	LG09: 33716381 .. 33716617 (+)
RNA-Seq Expression	Sed0016936
Synteny	Sed0016936

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGTGGTATAGGGTTTGAAGTGGTTAATTACTGATTTGGACAGGAAAGATGGTGTGGCCAGAGCTGCTGGGAGTGAAAGGAGAGGAGGCGAAGAGGAGGATAGAAAAGGAAAATCCATATGTCGACGTGGCAGTGACCCGAGAAGGGAGGCTCGTGACTTTTGATATTCGCTGCAATCGGGTTAGGGTTTGGGTTAGCCCTAATGGAATCGTCACTCGAATTCCAATCATTGGCTGA

mRNA sequence

ATGTGGTATAGGATGGTGTGGCCAGAGCTGCTGGGAGTGAAAGGAGAGGAGGCGAAGAGGAGGATAGAAAAGGAAAATCCATATGTCGACGTGGCAGTGACCCGAGAAGGGAGGCTCGTGACTTTTGATATTCGCTGCAATCGGGTTAGGGTTTGGGTTAGCCCTAATGGAATCGTCACTCGAATTCCAATCATTGGCTGA

Coding sequence (CDS)

ATGTGGTATAGGATGGTGTGGCCAGAGCTGCTGGGAGTGAAAGGAGAGGAGGCGAAGAGGAGGATAGAAAAGGAAAATCCATATGTCGACGTGGCAGTGACCCGAGAAGGGAGGCTCGTGACTTTTGATATTCGCTGCAATCGGGTTAGGGTTTGGGTTAGCCCTAATGGAATCGTCACTCGAATTCCAATCATTGGCTGA

Protein sequence

MWYRMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG

Homology

[Close]

BLAST of Sed0016936 vs. NCBI nr
Match: XP_022991208.1 (glu S.griseus protease inhibitor-like isoform X2 [Cucurbita maxima])

HSP 1 Score: 105.9 bits (263), Expect = 1.3e-19
Identity = 45/63 (71.43%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT DIRC+RVRVWV+ +GIVTR+P
Sbjct: 8  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDIRCDRVRVWVNEDGIVTRVP 67

Query: 64 IIG 67
           +G
Sbjct: 68 FVG 70

[Close]

BLAST of Sed0016936 vs. NCBI nr
Match: XP_022991207.1 (glu S.griseus protease inhibitor-like isoform X1 [Cucurbita maxima])

HSP 1 Score: 105.9 bits (263), Expect = 1.3e-19
Identity = 45/63 (71.43%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT DIRC+RVRVWV+ +GIVTR+P
Sbjct: 9  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDIRCDRVRVWVNEDGIVTRVP 68

Query: 64 IIG 67
           +G
Sbjct: 69 FVG 71

[Close]

BLAST of Sed0016936 vs. NCBI nr
Match: KGN44697.1 (hypothetical protein Csa_016107 [Cucumis sativus])

HSP 1 Score: 105.5 bits (262), Expect = 1.8e-19
Identity = 49/68 (72.06%), Postives = 57/68 (83.82%), Query Frame = 0


Query: 1  MWYR--MVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGI 60
          +W R  M WPELLG + EEAK RI KENPYVDVAV REGR+VTFDIRC+RVRVWV+ +G+
Sbjct: 3  LWCRGKMAWPELLGTRSEEAKSRIVKENPYVDVAVIREGRVVTFDIRCDRVRVWVNRDGV 62

Query: 61 VTRIPIIG 67
          VTRIP +G
Sbjct: 63 VTRIPFVG 70

[Close]

BLAST of Sed0016936 vs. NCBI nr
Match: XP_022953422.1 (glu S.griseus protease inhibitor-like isoform X2 [Cucurbita moschata] >XP_023547558.1 glu S.griseus protease inhibitor-like isoform X2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 104.8 bits (260), Expect = 3.0e-19
Identity = 43/63 (68.25%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT D+RC+RVR+WV+ +GIVTR+P
Sbjct: 8  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDLRCDRVRIWVNEDGIVTRVP 67

Query: 64 IIG 67
           +G
Sbjct: 68 FVG 70

[Close]

BLAST of Sed0016936 vs. NCBI nr
Match: XP_022953421.1 (glu S.griseus protease inhibitor-like isoform X1 [Cucurbita moschata] >XP_023547557.1 glu S.griseus protease inhibitor-like isoform X1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 104.8 bits (260), Expect = 3.0e-19
Identity = 43/63 (68.25%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT D+RC+RVR+WV+ +GIVTR+P
Sbjct: 9  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDLRCDRVRIWVNEDGIVTRVP 68

Query: 64 IIG 67
           +G
Sbjct: 69 FVG 71

[Close]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot
Match: P24076 (Glu S.griseus protease inhibitor OS=Momordica charantia OX=3673 PE=1 SV=1)

HSP 1 Score: 69.3 bits (168), Expect = 1.8e-11
Identity = 33/60 (55.00%), Postives = 39/60 (65.00%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WP+L+G  G  AK  IE+ENP V   + R G  VT D RC+RVRVWV+  GIV R P IG
Sbjct: 9  WPQLVGSTGAAAKAVIERENPRVRAVIVRVGSPVTADFRCDRVRVWVTERGIVARPPAIG 68

[Close]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot
Match: P19873 (Inhibitor of trypsin and hageman factor OS=Cucurbita maxima OX=3661 PE=1 SV=1)

HSP 1 Score: 67.4 bits (163), Expect = 6.9e-11
Identity = 31/60 (51.67%), Postives = 38/60 (63.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WP L+GV G  AK  IE++NP V   +  EG  VT D RCNRVR+WV+  G+V   P IG
Sbjct: 9  WPHLVGVGGSVAKAIIERQNPNVKAVILEEGTPVTKDFRCNRVRIWVNKRGLVVSPPRIG 68

[Close]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot
Match: Q6XNP7 (Protease inhibitor HPI OS=Hevea brasiliensis OX=3981 GN=PI1 PE=1 SV=2)

HSP 1 Score: 58.5 bits (140), Expect = 3.2e-08
Identity = 28/60 (46.67%), Postives = 38/60 (63.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WPEL+G  G+ A   I+ EN  V   V +EG  +T D+  NRVRV+V  N +VT++P IG
Sbjct: 11 WPELVGTNGDIAAGIIQTENANVKAIVVKEGLPITQDLNFNRVRVFVDENRVVTQVPAIG 70

[Close]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot
Match: P82381 (Proteinase inhibitor OS=Linum usitatissimum OX=4006 PE=1 SV=1)

HSP 1 Score: 56.2 bits (134), Expect = 1.6e-07
Identity = 27/59 (45.76%), Postives = 37/59 (62.71%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPII 66
          WPEL+G  G  A   +E+EN  V   V +EG  +T D RC+RV V V+ +G+VT +P I
Sbjct: 10 WPELVGKSGNMAAATVERENRNVHAIVLKEGSAMTKDFRCDRVWVIVNDHGVVTSVPHI 68

[Close]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot
Match: Q00783 (Proteinase inhibitor 1 OS=Solanum tuberosum OX=4113 PE=3 SV=1)

HSP 1 Score: 55.1 bits (131), Expect = 3.6e-07
Identity = 29/64 (45.31%), Postives = 42/64 (65.62%), Query Frame = 0


Query: 4   RMVWPELLGVKGEEAKRRIEKENPYV-DVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRI 63
           ++ WPEL+GV  + AK  IEKEN  + +V +   G  VT DIRC+RVR++ +  G V  I
Sbjct: 44  KLRWPELIGVPTKLAKGIIEKENSLISNVHILLNGSPVTLDIRCDRVRLFDNILGYVVDI 103

Query: 64  PIIG 67
           P++G
Sbjct: 104 PVVG 107

[Close]

BLAST of Sed0016936 vs. ExPASy TrEMBL
Match: A0A6J1JVI1 (glu S.griseus protease inhibitor-like isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC111487932 PE=3 SV=1)

HSP 1 Score: 105.9 bits (263), Expect = 6.5e-20
Identity = 45/63 (71.43%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT DIRC+RVRVWV+ +GIVTR+P
Sbjct: 8  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDIRCDRVRVWVNEDGIVTRVP 67

Query: 64 IIG 67
           +G
Sbjct: 68 FVG 70

[Close]

BLAST of Sed0016936 vs. ExPASy TrEMBL
Match: A0A6J1JL51 (glu S.griseus protease inhibitor-like isoform X1 OS=Cucurbita maxima OX=3661 GN=LOC111487932 PE=3 SV=1)

HSP 1 Score: 105.9 bits (263), Expect = 6.5e-20
Identity = 45/63 (71.43%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT DIRC+RVRVWV+ +GIVTR+P
Sbjct: 9  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDIRCDRVRVWVNEDGIVTRVP 68

Query: 64 IIG 67
           +G
Sbjct: 69 FVG 71

[Close]

BLAST of Sed0016936 vs. ExPASy TrEMBL
Match: A0A0A0K8J9 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_7G372910 PE=3 SV=1)

HSP 1 Score: 105.5 bits (262), Expect = 8.5e-20
Identity = 49/68 (72.06%), Postives = 57/68 (83.82%), Query Frame = 0


Query: 1  MWYR--MVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGI 60
          +W R  M WPELLG + EEAK RI KENPYVDVAV REGR+VTFDIRC+RVRVWV+ +G+
Sbjct: 3  LWCRGKMAWPELLGTRSEEAKSRIVKENPYVDVAVIREGRVVTFDIRCDRVRVWVNRDGV 62

Query: 61 VTRIPIIG 67
          VTRIP +G
Sbjct: 63 VTRIPFVG 70

[Close]

BLAST of Sed0016936 vs. ExPASy TrEMBL
Match: A0A6J1GN66 (glu S.griseus protease inhibitor-like isoform X2 OS=Cucurbita moschata OX=3662 GN=LOC111455981 PE=3 SV=1)

HSP 1 Score: 104.8 bits (260), Expect = 1.4e-19
Identity = 43/63 (68.25%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT D+RC+RVR+WV+ +GIVTR+P
Sbjct: 8  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDLRCDRVRIWVNEDGIVTRVP 67

Query: 64 IIG 67
           +G
Sbjct: 68 FVG 70

[Close]

BLAST of Sed0016936 vs. ExPASy TrEMBL
Match: A0A6J1GMZ2 (glu S.griseus protease inhibitor-like isoform X1 OS=Cucurbita moschata OX=3662 GN=LOC111455981 PE=3 SV=1)

HSP 1 Score: 104.8 bits (260), Expect = 1.4e-19
Identity = 43/63 (68.25%), Postives = 56/63 (88.89%), Query Frame = 0


Query: 4  RMVWPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIP 63
          +M+WPELLG +GEEA+ RIEKENPYVD A+ REGR+VT D+RC+RVR+WV+ +GIVTR+P
Sbjct: 9  KMMWPELLGARGEEARSRIEKENPYVDAAIVREGRVVTLDLRCDRVRIWVNEDGIVTRVP 68

Query: 64 IIG 67
           +G
Sbjct: 69 FVG 71

[Close]

BLAST of Sed0016936 vs. TAIR 10
Match: AT5G43580.1 (Serine protease inhibitor, potato inhibitor I-type family protein )

HSP 1 Score: 67.8 bits (164), Expect = 3.8e-12
Identity = 32/60 (53.33%), Postives = 41/60 (68.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WPELLG KGE+AK  IE+ENP +   +  +G +V     C+RV VWV+  GIV +IPIIG
Sbjct: 40 WPELLGAKGEDAKEVIERENPKMKAVIILDGTVVPEIFICSRVYVWVNDCGIVVQIPIIG 99

[Close]

BLAST of Sed0016936 vs. TAIR 10
Match: AT2G38870.1 (Serine protease inhibitor, potato inhibitor I-type family protein )

HSP 1 Score: 61.2 bits (147), Expect = 3.5e-10
Identity = 31/60 (51.67%), Postives = 38/60 (63.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WPEL G  G+ A   IE+ENP V+ AV  +G  VT D RC+RVRV+V  N IV + P  G
Sbjct: 11 WPELTGTNGDYAAVVIERENPTVNAAVILDGSPVTADFRCDRVRVFVDGNRIVVKTPKSG 70

[Close]

BLAST of Sed0016936 vs. TAIR 10
Match: AT2G38900.1 (Serine protease inhibitor, potato inhibitor I-type family protein )

HSP 1 Score: 57.8 bits (138), Expect = 3.9e-09
Identity = 29/60 (48.33%), Postives = 35/60 (58.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WPELLG  G+ A   I+ EN  ++V V  +G  VT D+ C RVRVWV    IV R P  G
Sbjct: 14 WPELLGTNGDYAASVIKGENSSLNVVVVSDGNYVTEDLSCYRVRVWVDEIRIVVRNPTAG 73

[Close]

BLAST of Sed0016936 vs. TAIR 10
Match: AT2G38900.2 (Serine protease inhibitor, potato inhibitor I-type family protein )

HSP 1 Score: 57.8 bits (138), Expect = 3.9e-09
Identity = 29/60 (48.33%), Postives = 35/60 (58.33%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPIIG 66
          WPELLG  G+ A   I+ EN  ++V V  +G  VT D+ C RVRVWV    IV R P  G
Sbjct: 29 WPELLGTNGDYAASVIKGENSSLNVVVVSDGNYVTEDLSCYRVRVWVDEIRIVVRNPTAG 88

[Close]

BLAST of Sed0016936 vs. TAIR 10
Match: AT5G43570.1 (Serine protease inhibitor, potato inhibitor I-type family protein )

HSP 1 Score: 54.7 bits (130), Expect = 3.3e-08
Identity = 27/58 (46.55%), Postives = 36/58 (62.07%), Query Frame = 0


Query: 7  WPELLGVKGEEAKRRIEKENPYVDVAVTREGRLVTFDIRCNRVRVWVSPNGIVTRIPI 65
          WPEL+G +GEE K  I++EN  V   +  E  +V   + C+RV V V+  GIVTR PI
Sbjct: 17 WPELVGRRGEEVKEIIDRENTKVTAKIISENAVVLAVVICDRVYVRVNDQGIVTRTPI 74

The following BLAST results are available for this feature:

BLAST of Sed0016936 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022991208.1	1.3e-19	71.43	glu S.griseus protease inhibitor-like isoform X2 [Cucurbita maxima]	[more]
XP_022991207.1	1.3e-19	71.43	glu S.griseus protease inhibitor-like isoform X1 [Cucurbita maxima]	[more]
KGN44697.1	1.8e-19	72.06	hypothetical protein Csa_016107 [Cucumis sativus]	[more]
XP_022953422.1	3.0e-19	68.25	glu S.griseus protease inhibitor-like isoform X2 [Cucurbita moschata] >XP_023547...	[more]
XP_022953421.1	3.0e-19	68.25	glu S.griseus protease inhibitor-like isoform X1 [Cucurbita moschata] >XP_023547...	[more]

BLAST of Sed0016936 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
P24076	1.8e-11	55.00	Glu S.griseus protease inhibitor OS=Momordica charantia OX=3673 PE=1 SV=1	[more]
P19873	6.9e-11	51.67	Inhibitor of trypsin and hageman factor OS=Cucurbita maxima OX=3661 PE=1 SV=1	[more]
Q6XNP7	3.2e-08	46.67	Protease inhibitor HPI OS=Hevea brasiliensis OX=3981 GN=PI1 PE=1 SV=2	[more]
P82381	1.6e-07	45.76	Proteinase inhibitor OS=Linum usitatissimum OX=4006 PE=1 SV=1	[more]
Q00783	3.6e-07	45.31	Proteinase inhibitor 1 OS=Solanum tuberosum OX=4113 PE=3 SV=1	[more]

BLAST of Sed0016936 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1JVI1	6.5e-20	71.43	glu S.griseus protease inhibitor-like isoform X2 OS=Cucurbita maxima OX=3661 GN=...	[more]
A0A6J1JL51	6.5e-20	71.43	glu S.griseus protease inhibitor-like isoform X1 OS=Cucurbita maxima OX=3661 GN=...	[more]
A0A0A0K8J9	8.5e-20	72.06	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_7G372910 PE=3 SV=1	[more]
A0A6J1GN66	1.4e-19	68.25	glu S.griseus protease inhibitor-like isoform X2 OS=Cucurbita moschata OX=3662 G...	[more]
A0A6J1GMZ2	1.4e-19	68.25	glu S.griseus protease inhibitor-like isoform X1 OS=Cucurbita moschata OX=3662 G...	[more]

BLAST of Sed0016936 vs. TAIR 10


Match Name	E-value	Identity	Description
AT5G43580.1	3.8e-12	53.33	Serine protease inhibitor, potato inhibitor I-type family protein	[more]
AT2G38870.1	3.5e-10	51.67	Serine protease inhibitor, potato inhibitor I-type family protein	[more]
AT2G38900.1	3.9e-09	48.33	Serine protease inhibitor, potato inhibitor I-type family protein	[more]
AT2G38900.2	3.9e-09	48.33	Serine protease inhibitor, potato inhibitor I-type family protein	[more]
AT5G43570.1	3.3e-08	46.55	Serine protease inhibitor, potato inhibitor I-type family protein	[more]

InterPro

Analysis Name: InterPro Annotations of Chayote (edule) v1
Date Performed: 2021-10-25

Position :

Zoom :

x 1


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000864	Proteinase inhibitor I13, potato inhibitor I	PRINTS	PR00292	POTATOINHBTR	coord: 31..42 score: 29.71 coord: 43..53 score: 60.87 coord: 6..19 score: 53.73
IPR000864	Proteinase inhibitor I13, potato inhibitor I	PFAM	PF00280	potato_inhibit	coord: 7..66 e-value: 3.4E-24 score: 85.3
IPR000864	Proteinase inhibitor I13, potato inhibitor I	PANTHER	PTHR33091	PROTEIN, PUTATIVE, EXPRESSED-RELATED	coord: 5..66
IPR000864	Proteinase inhibitor I13, potato inhibitor I	PROSITE	PS00285	POTATO_INHIBITOR	coord: 7..18
None	No IPR available	GENE3D	3.30.10.10	Trypsin Inhibitor V, subunit A	coord: 3..66 e-value: 2.1E-25 score: 90.7
None	No IPR available	PANTHER	PTHR33091:SF41	SERINE PROTEASE INHIBITOR, POTATO INHIBITOR I-TYPE FAMILY PROTEIN-RELATED	coord: 5..66
IPR036354	Proteinase inhibitor I13, potato inhibitor I superfamily	SUPERFAMILY	54654	CI-2 family of serine protease inhibitors	coord: 3..66

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Sed0016936.1	Sed0016936.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0010951	negative regulation of endopeptidase activity
biological_process	GO:0009611	response to wounding
molecular_function	GO:0004867	serine-type endopeptidase inhibitor activity