MS002731 (gene) Bitter gourd (TR) v1

Overview


Name	MS002731
Type	gene
Organism	Momordica charantia cv. TR (Bitter gourd (TR) v1)
Description	Cytochrome c oxidase copper chaperone
Location	scaffold66: 65445 .. 65684 (-)
RNA-Seq Expression	MS002731
Synteny	MS002731

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGGTGGGCTACCAGTTGGAAACGGTTCTTCTGCCCTAGCTTTTCCGGAGTCCAAACTTGACCAAGGGTCAGCAGTGGTCAAGTCTACCACAGATGGGAAACCAAAAAAGAGGATTTGTTGTGCCTGTCCTGAGACTAAGAAGCTAAGAGATGAGTGCATCGTGGAGCATGGGGAAGAAGCCTGTGGAAAATGGATTGAGGCTCATCGTAAGTGTCTTCGTGCGGAGGGATTCAATGTC

mRNA sequence

ATGGGTGGGCTACCAGTTGGAAACGGTTCTTCTGCCCTAGCTTTTCCGGAGTCCAAACTTGACCAAGGGTCAGCAGTGGTCAAGTCTACCACAGATGGGAAACCAAAAAAGAGGATTTGTTGTGCCTGTCCTGAGACTAAGAAGCTAAGAGATGAGTGCATCGTGGAGCATGGGGAAGAAGCCTGTGGAAAATGGATTGAGGCTCATCGTAAGTGTCTTCGTGCGGAGGGATTCAATGTC

Coding sequence (CDS)

ATGGGTGGGCTACCAGTTGGAAACGGTTCTTCTGCCCTAGCTTTTCCGGAGTCCAAACTTGACCAAGGGTCAGCAGTGGTCAAGTCTACCACAGATGGGAAACCAAAAAAGAGGATTTGTTGTGCCTGTCCTGAGACTAAGAAGCTAAGAGATGAGTGCATCGTGGAGCATGGGGAAGAAGCCTGTGGAAAATGGATTGAGGCTCATCGTAAGTGTCTTCGTGCGGAGGGATTCAATGTC

Protein sequence

MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV

Homology

[Close]

BLAST of MS002731 vs. NCBI nr
Match: XP_022142851.1 (cytochrome c oxidase copper chaperone 1-like [Momordica charantia] >XP_022142852.1 cytochrome c oxidase copper chaperone 1-like [Momordica charantia])

HSP 1 Score: 168.7 bits (426), Expect = 2.0e-38
Identity = 79/80 (98.75%), Postives = 79/80 (98.75%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPVGNGSSALA PESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE
Sbjct: 1  MGGLPVGNGSSALALPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. NCBI nr
Match: KAA0060636.1 (cytochrome c oxidase copper chaperone 2-like [Cucumis melo var. makuwa] >TYK02235.1 cytochrome c oxidase copper chaperone 2-like [Cucumis melo var. makuwa])

HSP 1 Score: 153.7 bits (387), Expect = 6.8e-34
Identity = 71/80 (88.75%), Postives = 74/80 (92.50%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESKLDQ S VVKST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKLDQASTVVKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. NCBI nr
Match: XP_038905291.1 (cytochrome c oxidase copper chaperone 1-like [Benincasa hispida] >XP_038905292.1 cytochrome c oxidase copper chaperone 1-like [Benincasa hispida] >XP_038905293.1 cytochrome c oxidase copper chaperone 1-like [Benincasa hispida])

HSP 1 Score: 153.7 bits (387), Expect = 6.8e-34
Identity = 71/80 (88.75%), Postives = 75/80 (93.75%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESK DQG+AVVKST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKHDQGAAVVKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. NCBI nr
Match: XP_004133710.1 (cytochrome c oxidase copper chaperone 2 [Cucumis sativus] >XP_004133711.1 cytochrome c oxidase copper chaperone 2 [Cucumis sativus] >XP_011650564.1 cytochrome c oxidase copper chaperone 2 [Cucumis sativus] >XP_031737625.1 cytochrome c oxidase copper chaperone 2 [Cucumis sativus])

HSP 1 Score: 153.3 bits (386), Expect = 8.9e-34
Identity = 70/80 (87.50%), Postives = 74/80 (92.50%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESKLDQ S V+KST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKLDQASTVIKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. NCBI nr
Match: KGN56261.2 (hypothetical protein Csa_011168 [Cucumis sativus])

HSP 1 Score: 153.3 bits (386), Expect = 8.9e-34
Identity = 70/80 (87.50%), Postives = 74/80 (92.50%), Query Frame = 0


Query: 1   MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
           MGGLPV N SSA+A PESKLDQ S V+KST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 97  MGGLPVVNSSSAIALPESKLDQASTVIKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 156

Query: 61  ACGKWIEAHRKCLRAEGFNV 81
           ACGKWIEAHRKCLRAEGFNV
Sbjct: 157 ACGKWIEAHRKCLRAEGFNV 176

[Close]

BLAST of MS002731 vs. ExPASy Swiss-Prot
Match: Q9LJQ9 (Cytochrome c oxidase copper chaperone 1 OS=Arabidopsis thaliana OX=3702 GN=COX17-1 PE=2 SV=1)

HSP 1 Score: 98.6 bits (244), Expect = 3.4e-20
Identity = 42/52 (80.77%), Postives = 47/52 (90.38%), Query Frame = 0


Query: 29 STTDGKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          ++ + KPKKRICCACP+TKKLRDECIVEHGE AC KWIEAH+ CLRAEGFNV
Sbjct: 23 ASAETKPKKRICCACPDTKKLRDECIVEHGESACTKWIEAHKICLRAEGFNV 74

[Close]

BLAST of MS002731 vs. ExPASy Swiss-Prot
Match: Q94FT1 (Cytochrome c oxidase copper chaperone 2 OS=Arabidopsis thaliana OX=3702 GN=COX17-2 PE=3 SV=1)

HSP 1 Score: 95.1 bits (235), Expect = 3.8e-19
Identity = 41/50 (82.00%), Postives = 44/50 (88.00%), Query Frame = 0


Query: 31 TDGKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          T+ KPKKRICCACP+TKKLRDECIVEHGE AC KWIEAH  CLR+EGF V
Sbjct: 23 TETKPKKRICCACPDTKKLRDECIVEHGESACTKWIEAHILCLRSEGFKV 72

[Close]

BLAST of MS002731 vs. ExPASy Swiss-Prot
Match: Q54ID0 (Cytochrome c oxidase copper chaperone OS=Dictyostelium discoideum OX=44689 GN=cox17 PE=3 SV=1)

HSP 1 Score: 77.4 bits (189), Expect = 8.1e-14
Identity = 35/57 (61.40%), Postives = 43/57 (75.44%), Query Frame = 0


Query: 25 AVVKSTTD-GKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          A   +TT+   PKK++CCACPETKK+RDECIV +GEE C   IE H+ CLR EGF+V
Sbjct: 4  AETNTTTEVAAPKKKMCCACPETKKVRDECIVANGEEKCAALIELHKVCLRKEGFDV 60

[Close]

BLAST of MS002731 vs. ExPASy Swiss-Prot
Match: Q6J3Q7 (Cytochrome c oxidase copper chaperone OS=Canis lupus familiaris OX=9615 GN=COX17 PE=3 SV=3)

HSP 1 Score: 71.6 bits (174), Expect = 4.5e-12
Identity = 32/59 (54.24%), Postives = 42/59 (71.19%), Query Frame = 0


Query: 24 SAVVKSTTDGKPKKRI--CCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          +A   + +D + KK +  CCACPETKK RD CI+E GEE CG  IEAH++C+RA GF +
Sbjct: 5  AAASPAPSDSQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI 63

[Close]

BLAST of MS002731 vs. ExPASy Swiss-Prot
Match: P81045 (Cytochrome c oxidase copper chaperone OS=Sus scrofa OX=9823 GN=COX17 PE=1 SV=1)

HSP 1 Score: 71.2 bits (173), Expect = 5.8e-12
Identity = 31/59 (52.54%), Postives = 42/59 (71.19%), Query Frame = 0


Query: 24 SAVVKSTTDGKPKKRI--CCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          +A + +  + + KK +  CCACPETKK RD CI+E GEE CG  IEAH++C+RA GF +
Sbjct: 4  AAAIPAPPESQEKKPLKPCCACPETKKARDACIIEKGEEHCGHLIEAHKECMRALGFKI 62

[Close]

BLAST of MS002731 vs. ExPASy TrEMBL
Match: A0A6J1CNF2 (cytochrome c oxidase copper chaperone 1-like OS=Momordica charantia OX=3673 GN=LOC111012862 PE=3 SV=1)

HSP 1 Score: 168.7 bits (426), Expect = 9.9e-39
Identity = 79/80 (98.75%), Postives = 79/80 (98.75%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPVGNGSSALA PESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE
Sbjct: 1  MGGLPVGNGSSALALPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. ExPASy TrEMBL
Match: A0A5D3BSU0 (Cytochrome c oxidase copper chaperone 2-like OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold18G00310 PE=3 SV=1)

HSP 1 Score: 153.7 bits (387), Expect = 3.3e-34
Identity = 71/80 (88.75%), Postives = 74/80 (92.50%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESKLDQ S VVKST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKLDQASTVVKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. ExPASy TrEMBL
Match: A0A0A0L5D1 (Cytochrome c oxidase copper chaperone OS=Cucumis sativus OX=3659 GN=Csa_3G105960 PE=3 SV=1)

HSP 1 Score: 153.3 bits (386), Expect = 4.3e-34
Identity = 70/80 (87.50%), Postives = 74/80 (92.50%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESKLDQ S V+KST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKLDQASTVIKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. ExPASy TrEMBL
Match: A0A1S4DYZ5 (LOW QUALITY PROTEIN: cytochrome c oxidase copper chaperone 2 OS=Cucumis melo OX=3656 GN=LOC103493331 PE=3 SV=1)

HSP 1 Score: 151.4 bits (381), Expect = 1.6e-33
Identity = 70/80 (87.50%), Postives = 73/80 (91.25%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPV N SSA+A PESKLDQ S VVKST DGKP K+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVVNSSSAIALPESKLDQASTVVKSTPDGKPXKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
          ACGKWIEAHRKCLRAEGFNV
Sbjct: 61 ACGKWIEAHRKCLRAEGFNV 80

[Close]

BLAST of MS002731 vs. ExPASy TrEMBL
Match: A0A6J1IMZ6 (cytochrome c oxidase copper chaperone 2 OS=Cucurbita maxima OX=3661 GN=LOC111477894 PE=3 SV=1)

HSP 1 Score: 142.5 bits (358), Expect = 7.6e-31
Identity = 68/80 (85.00%), Postives = 71/80 (88.75%), Query Frame = 0


Query: 1  MGGLPVGNGSSALAFPESKLDQGSAVVKSTTDGKPKKRICCACPETKKLRDECIVEHGEE 60
          MGGLPVGN S      ESKL+QGSAVVKST DGKPKK+ICCACP+TKKLRDECIVEHGEE
Sbjct: 1  MGGLPVGNSS------ESKLEQGSAVVKSTPDGKPKKKICCACPDTKKLRDECIVEHGEE 60

Query: 61 ACGKWIEAHRKCLRAEGFNV 81
           CGKWIEAHRKCLRAEGFNV
Sbjct: 61 FCGKWIEAHRKCLRAEGFNV 74

[Close]

BLAST of MS002731 vs. TAIR 10
Match: AT3G15352.1 (cytochrome c oxidase 17 )

HSP 1 Score: 98.6 bits (244), Expect = 2.4e-21
Identity = 42/52 (80.77%), Postives = 47/52 (90.38%), Query Frame = 0


Query: 29 STTDGKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          ++ + KPKKRICCACP+TKKLRDECIVEHGE AC KWIEAH+ CLRAEGFNV
Sbjct: 23 ASAETKPKKRICCACPDTKKLRDECIVEHGESACTKWIEAHKICLRAEGFNV 74

[Close]

BLAST of MS002731 vs. TAIR 10
Match: AT1G53030.1 (Cytochrome C oxidase copper chaperone (COX17) )

HSP 1 Score: 95.1 bits (235), Expect = 2.7e-20
Identity = 41/50 (82.00%), Postives = 44/50 (88.00%), Query Frame = 0


Query: 31 TDGKPKKRICCACPETKKLRDECIVEHGEEACGKWIEAHRKCLRAEGFNV 81
          T+ KPKKRICCACP+TKKLRDECIVEHGE AC KWIEAH  CLR+EGF V
Sbjct: 23 TETKPKKRICCACPDTKKLRDECIVEHGESACTKWIEAHILCLRSEGFKV 72

The following BLAST results are available for this feature:

BLAST of MS002731 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022142851.1	2.0e-38	98.75	cytochrome c oxidase copper chaperone 1-like [Momordica charantia] >XP_022142852...	[more]
KAA0060636.1	6.8e-34	88.75	cytochrome c oxidase copper chaperone 2-like [Cucumis melo var. makuwa] >TYK0223...	[more]
XP_038905291.1	6.8e-34	88.75	cytochrome c oxidase copper chaperone 1-like [Benincasa hispida] >XP_038905292.1...	[more]
XP_004133710.1	8.9e-34	87.50	cytochrome c oxidase copper chaperone 2 [Cucumis sativus] >XP_004133711.1 cytoch...	[more]
KGN56261.2	8.9e-34	87.50	hypothetical protein Csa_011168 [Cucumis sativus]	[more]

BLAST of MS002731 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9LJQ9	3.4e-20	80.77	Cytochrome c oxidase copper chaperone 1 OS=Arabidopsis thaliana OX=3702 GN=COX17...	[more]
Q94FT1	3.8e-19	82.00	Cytochrome c oxidase copper chaperone 2 OS=Arabidopsis thaliana OX=3702 GN=COX17...	[more]
Q54ID0	8.1e-14	61.40	Cytochrome c oxidase copper chaperone OS=Dictyostelium discoideum OX=44689 GN=co...	[more]
Q6J3Q7	4.5e-12	54.24	Cytochrome c oxidase copper chaperone OS=Canis lupus familiaris OX=9615 GN=COX17...	[more]
P81045	5.8e-12	52.54	Cytochrome c oxidase copper chaperone OS=Sus scrofa OX=9823 GN=COX17 PE=1 SV=1	[more]

BLAST of MS002731 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1CNF2	9.9e-39	98.75	cytochrome c oxidase copper chaperone 1-like OS=Momordica charantia OX=3673 GN=L...	[more]
A0A5D3BSU0	3.3e-34	88.75	Cytochrome c oxidase copper chaperone 2-like OS=Cucumis melo var. makuwa OX=1194...	[more]
A0A0A0L5D1	4.3e-34	87.50	Cytochrome c oxidase copper chaperone OS=Cucumis sativus OX=3659 GN=Csa_3G105960...	[more]
A0A1S4DYZ5	1.6e-33	87.50	LOW QUALITY PROTEIN: cytochrome c oxidase copper chaperone 2 OS=Cucumis melo OX=...	[more]
A0A6J1IMZ6	7.6e-31	85.00	cytochrome c oxidase copper chaperone 2 OS=Cucurbita maxima OX=3661 GN=LOC111477...	[more]

BLAST of MS002731 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G15352.1	2.4e-21	80.77	cytochrome c oxidase 17	[more]
AT1G53030.1	2.7e-20	82.00	Cytochrome C oxidase copper chaperone (COX17)	[more]

InterPro

Analysis Name: InterPro Annotations of Bitter gourd (TR) v1
Date Performed: 2021-10-25

Position :

Zoom :

x 1


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	1.10.287.1130	CytochromE C oxidase copper chaperone	coord: 17..80 e-value: 6.7E-25 score: 89.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..35
None	No IPR available	PANTHER	PTHR16719:SF6	CYTOCHROME C OXIDASE COPPER CHAPERONE	coord: 20..80
None	No IPR available	PROSITE	PS51808	CHCH	coord: 40..80 score: 12.781319
IPR007745	Cytochrome c oxidase copper chaperone	PFAM	PF05051	COX17	coord: 36..80 e-value: 1.3E-19 score: 70.3
IPR007745	Cytochrome c oxidase copper chaperone	PANTHER	PTHR16719	CYTOCHROME C OXIDASE COPPER CHAPERONE	coord: 20..80
IPR009069	Cysteine alpha-hairpin motif superfamily	SUPERFAMILY	47072	Cysteine alpha-hairpin motif	coord: 28..80

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MS002731.1	MS002731.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0005758	mitochondrial intermembrane space
molecular_function	GO:0016531	copper chaperone activity
molecular_function	GO:0005507	copper ion binding