MC07g_new0003 (gene) Bitter gourd (Dali-11) v1

Overview


Name	MC07g_new0003
Type	gene
Organism	Momordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
Description	Ribonuclease H
Location	MC07: 96968 .. 97880 (+)
RNA-Seq Expression	MC07g_new0003
Synteny	MC07g_new0003

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATACAAAGCACTAGTAGTAGGCCTACGAATGGCCGAAGCCATGGGAGCCACGCACTTGGATATAAGGAGCTACTCACAACTCGTAGTTAATCAGATCACCAAAGAGTACCAGGCCAAAGATAGTCGGATGGAGAGATACCTACACAAGGTGCGCGAGCTATTGTCTCGATTCCTAAGGCATACCATAGAGCGGGTATCGCGTGCAGAGAATGCTAACGCGGATGCCTTGGCAAAACTGACGTCTTCTTACCCGACCGAGCTATATAGGTCGATCCCAGTCGAGATTTTGGAAGCCCCCTCCATTCAAGAGCCAGAGGCAATGATTGTCGAAGCAGCGATACCGACTTGGATGGATTACATAAAAGCCTTCCTACGAGGAGAGGAACTCCCAGAACAAGTCGATCTCAAGAAAATGCGATGCAAGGCGACATGGTACGTTCTACGAGGTGATGTGTTGTACAAGAGGGGATTTTCCCTTCTGCTGCTGAGGTACGTAGACCCAGAGGAGGCGAACTACGTCTTGAGAGAAGTGCACGAAGGAGTTTGCGGCAAGCTGGTCAAGTAGGGTTATTACTAGCCCACTAAGGGACGAAATGCCATGAAGTTCACGCGGTGATGCGATCGATGCCAATGGTTTGCTACGACAATTGACCAGCCCCCCGAGCTCCTCACGCCAATCTCAGCTCCCTGACCATTCGCTTAGTGGAGGATTGACCTCATCGGACCTCTCCCACTAGGAAAAGGCCAAACAAAGTTCGCAATAGTGGCTATAGATTACTTCACCAAGTGAGCGGAGGCTGAGCCGTTAGCCACCATAACAGAGGCCAAAATCACAAACTTCGTGTGGACTAGTCTTATTTGTAGGTTTGGCATACCTCATGCCATCACCGACAATGGGAAACAGTTCGACAAC

mRNA sequence

ATGGCCGAAGCCATGGGAGCCACGCACTTGGATATAAGGAGCTACTCACAACTCGTAGTTAATCAGATCACCAAAGAGTACCAGGCCAAAGATAGTCGGATGGAGAGATACCTACACAAGGTGCGCGAGCTATTGTCTCGATTCCTAAGGCATACCATAGAGCGGGTATCGCGTGCAGAGAATGCTAACGCGGATGCCTTGGCAAAACTGACGTCTTCTTACCCGACCGAGCTATATAGGTCGATCCCAGTCGAGATTTTGGAAGCCCCCTCCATTCAAGAGCCAGAGGCAATGATTGTCGAAGCAGCGATACCGACTTGGATGGATTACATAAAAGCCTTCCTACGAGGAGAGGAACTCCCAGAACAAGTCGATCTCAAGAAAATGCGATGCAAGGCGACATGGTACGTTCTACGAGGTGATGTGTTGTACAAGAGGGGATTTTCCCTTCTGCTGCTGAGGTACGTAGACCCAGAGGAGGCGAACTACGTCTTGAGAGAAGTGCACGAAGGAGTTTGCGGCAAGCTGGTCAAGTAG

Coding sequence (CDS)

ATGGCCGAAGCCATGGGAGCCACGCACTTGGATATAAGGAGCTACTCACAACTCGTAGTTAATCAGATCACCAAAGAGTACCAGGCCAAAGATAGTCGGATGGAGAGATACCTACACAAGGTGCGCGAGCTATTGTCTCGATTCCTAAGGCATACCATAGAGCGGGTATCGCGTGCAGAGAATGCTAACGCGGATGCCTTGGCAAAACTGACGTCTTCTTACCCGACCGAGCTATATAGGTCGATCCCAGTCGAGATTTTGGAAGCCCCCTCCATTCAAGAGCCAGAGGCAATGATTGTCGAAGCAGCGATACCGACTTGGATGGATTACATAAAAGCCTTCCTACGAGGAGAGGAACTCCCAGAACAAGTCGATCTCAAGAAAATGCGATGCAAGGCGACATGGTACGTTCTACGAGGTGATGTGTTGTACAAGAGGGGATTTTCCCTTCTGCTGCTGAGGTACGTAGACCCAGAGGAGGCGAACTACGTCTTGAGAGAAGTGCACGAAGGAGTTTGCGGCAAGCTGGTCAAGTAG

Protein sequence

MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAENANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEELPEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCGKLVK

Homology

[Close]

BLAST of MC07g_new0003 vs. NCBI nr
Match: XP_022157610.1 (uncharacterized protein LOC111024267 [Momordica charantia])

HSP 1 Score: 194 bits (492), Expect = 5.37e-57
Identity = 96/174 (55.17%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A+ +GATH+ + + SQLVVNQI +EY+AKDSRME+YL KVR  L++F  + + +V R E
Sbjct: 108 VAKGLGATHIKVFNDSQLVVNQIKEEYKAKDSRMEKYLSKVRSHLAQFKTYEVNQVPRLE 167

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+N DALAKL S+Y T+L RSIPVEIL+ PSI EP+ M V+A  P WMD +  F++G   
Sbjct: 168 NSNVDALAKLASAYETDLARSIPVEILDNPSILEPDIMDVDATAPMWMDPVVEFIKGNPP 227

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + KKM  +A  +VLR   LY RGFSL LL+   PEE NY+LRE+HEGVCG
Sbjct: 228 QDSKEHKKMARRAAQFVLRDGALYSRGFSLPLLKCATPEEGNYILREIHEGVCG 281

[Close]

BLAST of MC07g_new0003 vs. NCBI nr
Match: XP_022158860.1 (uncharacterized protein LOC111025322 [Momordica charantia])

HSP 1 Score: 186 bits (472), Expect = 4.42e-54
Identity = 95/174 (54.60%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A A+GA+H+ + S SQLVV+QI +EYQAKDSRME+YL KVR  L +F  + + +V RAE
Sbjct: 153 IARALGASHIKVFSDSQLVVSQIKEEYQAKDSRMEKYLSKVRSYLIQFRTYEVSQVPRAE 212

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NA+ALAKL  +Y T+L RS+PVEIL+ PSI EP+ M V+   P+WMD I  F++G   
Sbjct: 213 NSNANALAKLALAYETDLARSVPVEILDGPSILEPDLMEVDTPEPSWMDPIVDFIKGNSP 272

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
           P+  + KKM  KA  +V++   LY+R FSL LL+ V  EE  YVLRE+HEGVCG
Sbjct: 273 PDPKEHKKMARKAARFVIQDGALYRRSFSLPLLKCVTLEEGLYVLREIHEGVCG 326

[Close]

BLAST of MC07g_new0003 vs. NCBI nr
Match: XP_022150100.1 (uncharacterized protein LOC111018362 [Momordica charantia])

HSP 1 Score: 192 bits (488), Expect = 5.31e-54
Identity = 95/174 (54.60%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A  +GA H+ + S SQLVVNQI +EYQ KD RME+YL KVR  L++F  + + +V R+E
Sbjct: 344 VARGLGAVHIKVFSDSQLVVNQIKEEYQTKDPRMEKYLSKVRSHLAQFRTYEVSQVPRSE 403

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T+L RS+PVEIL++PSI EP+ M V+   P+WMD I  F++G  L
Sbjct: 404 NSNADALAKLASAYETDLARSVPVEILDSPSILEPDVMEVDTPSPSWMDPIVEFIKGNPL 463

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + KKM  +A  + LR   LY+RGFSL LL+ V PEE  Y+LRE+HEGVCG
Sbjct: 464 QDPKEQKKMARRAARFTLREGALYRRGFSLPLLKCVTPEEGLYILREIHEGVCG 517

[Close]

BLAST of MC07g_new0003 vs. NCBI nr
Match: XP_022136647.1 (uncharacterized protein LOC111008302 [Momordica charantia])

HSP 1 Score: 189 bits (481), Expect = 9.89e-54
Identity = 97/174 (55.75%), Postives = 128/174 (73.56%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A A+GA+ + + S SQLVV+QI +EYQAKDSRME+YL KVR  L++F  + + RV RAE
Sbjct: 195 IARALGASCVKVFSDSQLVVSQIKEEYQAKDSRMEKYLGKVRSHLAQFRTYEVSRVPRAE 254

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T L RS+PVEIL+ PSI EP+ M + A   +WMD I  F+RG   
Sbjct: 255 NSNADALAKLASAYETNLARSVPVEILDNPSISEPDLMEIGAPESSWMDPIADFIRGNSP 314

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + +K+  +A  +V+RG+ LY+RGFSL LLR + PEE  YVLRE+HEGVCG
Sbjct: 315 QDPKERRKLARRAARFVVRGEALYRRGFSLPLLRCLTPEEGLYVLREIHEGVCG 368

[Close]

BLAST of MC07g_new0003 vs. NCBI nr
Match: XP_022151715.1 (uncharacterized protein LOC111019628 [Momordica charantia])

HSP 1 Score: 184 bits (467), Expect = 1.47e-53
Identity = 93/174 (53.45%), Postives = 124/174 (71.26%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A+ +GA H+ + S SQLV NQI +EYQ KD RME+YL +VR  L++F  + + +V R+E
Sbjct: 153 VAKGLGAIHIKVFSDSQLVGNQIKEEYQTKDPRMEKYLSRVRSHLAQFETYEVSQVPRSE 212

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T+L RS+PVEIL+ PSI +P+ M ++   P+WMD I  F++G   
Sbjct: 213 NSNADALAKLASAYETDLARSVPVEILDNPSILDPDVMEIDIPSPSWMDPIVEFIQGNPP 272

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            E  + KKM  KA  +VLR   LY+RGFSL LL+ V PEE  Y+LRE HEGVCG
Sbjct: 273 QELKEQKKMARKAARFVLRDGALYRRGFSLPLLKCVTPEEGLYILREFHEGVCG 326

[Close]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL
Match: A0A6J1DTK4 (uncharacterized protein LOC111024267 OS=Momordica charantia OX=3673 GN=LOC111024267 PE=4 SV=1)

HSP 1 Score: 194 bits (492), Expect = 2.60e-57
Identity = 96/174 (55.17%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A+ +GATH+ + + SQLVVNQI +EY+AKDSRME+YL KVR  L++F  + + +V R E
Sbjct: 108 VAKGLGATHIKVFNDSQLVVNQIKEEYKAKDSRMEKYLSKVRSHLAQFKTYEVNQVPRLE 167

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+N DALAKL S+Y T+L RSIPVEIL+ PSI EP+ M V+A  P WMD +  F++G   
Sbjct: 168 NSNVDALAKLASAYETDLARSIPVEILDNPSILEPDIMDVDATAPMWMDPVVEFIKGNPP 227

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + KKM  +A  +VLR   LY RGFSL LL+   PEE NY+LRE+HEGVCG
Sbjct: 228 QDSKEHKKMARRAAQFVLRDGALYSRGFSLPLLKCATPEEGNYILREIHEGVCG 281

[Close]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL
Match: A0A6J1DX12 (uncharacterized protein LOC111025322 OS=Momordica charantia OX=3673 GN=LOC111025322 PE=4 SV=1)

HSP 1 Score: 186 bits (472), Expect = 2.14e-54
Identity = 95/174 (54.60%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A A+GA+H+ + S SQLVV+QI +EYQAKDSRME+YL KVR  L +F  + + +V RAE
Sbjct: 153 IARALGASHIKVFSDSQLVVSQIKEEYQAKDSRMEKYLSKVRSYLIQFRTYEVSQVPRAE 212

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NA+ALAKL  +Y T+L RS+PVEIL+ PSI EP+ M V+   P+WMD I  F++G   
Sbjct: 213 NSNANALAKLALAYETDLARSVPVEILDGPSILEPDLMEVDTPEPSWMDPIVDFIKGNSP 272

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
           P+  + KKM  KA  +V++   LY+R FSL LL+ V  EE  YVLRE+HEGVCG
Sbjct: 273 PDPKEHKKMARKAARFVIQDGALYRRSFSLPLLKCVTLEEGLYVLREIHEGVCG 326

[Close]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL
Match: A0A6J1D7J6 (Ribonuclease H OS=Momordica charantia OX=3673 GN=LOC111018362 PE=4 SV=1)

HSP 1 Score: 192 bits (488), Expect = 2.57e-54
Identity = 95/174 (54.60%), Postives = 126/174 (72.41%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A  +GA H+ + S SQLVVNQI +EYQ KD RME+YL KVR  L++F  + + +V R+E
Sbjct: 344 VARGLGAVHIKVFSDSQLVVNQIKEEYQTKDPRMEKYLSKVRSHLAQFRTYEVSQVPRSE 403

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T+L RS+PVEIL++PSI EP+ M V+   P+WMD I  F++G  L
Sbjct: 404 NSNADALAKLASAYETDLARSVPVEILDSPSILEPDVMEVDTPSPSWMDPIVEFIKGNPL 463

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + KKM  +A  + LR   LY+RGFSL LL+ V PEE  Y+LRE+HEGVCG
Sbjct: 464 QDPKEQKKMARRAARFTLREGALYRRGFSLPLLKCVTPEEGLYILREIHEGVCG 517

[Close]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL
Match: A0A6J1C617 (Ribonuclease H OS=Momordica charantia OX=3673 GN=LOC111008302 PE=4 SV=1)

HSP 1 Score: 189 bits (481), Expect = 4.79e-54
Identity = 97/174 (55.75%), Postives = 128/174 (73.56%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A A+GA+ + + S SQLVV+QI +EYQAKDSRME+YL KVR  L++F  + + RV RAE
Sbjct: 195 IARALGASCVKVFSDSQLVVSQIKEEYQAKDSRMEKYLGKVRSHLAQFRTYEVSRVPRAE 254

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T L RS+PVEIL+ PSI EP+ M + A   +WMD I  F+RG   
Sbjct: 255 NSNADALAKLASAYETNLARSVPVEILDNPSISEPDLMEIGAPESSWMDPIADFIRGNSP 314

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            +  + +K+  +A  +V+RG+ LY+RGFSL LLR + PEE  YVLRE+HEGVCG
Sbjct: 315 QDPKERRKLARRAARFVVRGEALYRRGFSLPLLRCLTPEEGLYVLREIHEGVCG 368

[Close]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL
Match: A0A6J1DBZ0 (uncharacterized protein LOC111019628 OS=Momordica charantia OX=3673 GN=LOC111019628 PE=4 SV=1)

HSP 1 Score: 184 bits (467), Expect = 7.10e-54
Identity = 93/174 (53.45%), Postives = 124/174 (71.26%), Query Frame = 0


Query: 1   MAEAMGATHLDIRSYSQLVVNQITKEYQAKDSRMERYLHKVRELLSRFLRHTIERVSRAE 60
           +A+ +GA H+ + S SQLV NQI +EYQ KD RME+YL +VR  L++F  + + +V R+E
Sbjct: 153 VAKGLGAIHIKVFSDSQLVGNQIKEEYQTKDPRMEKYLSRVRSHLAQFETYEVSQVPRSE 212

Query: 61  NANADALAKLTSSYPTELYRSIPVEILEAPSIQEPEAMIVEAAIPTWMDYIKAFLRGEEL 120
           N+NADALAKL S+Y T+L RS+PVEIL+ PSI +P+ M ++   P+WMD I  F++G   
Sbjct: 213 NSNADALAKLASAYETDLARSVPVEILDNPSILDPDVMEIDIPSPSWMDPIVEFIQGNPP 272

Query: 121 PEQVDLKKMRCKATWYVLRGDVLYKRGFSLLLLRYVDPEEANYVLREVHEGVCG 174
            E  + KKM  KA  +VLR   LY+RGFSL LL+ V PEE  Y+LRE HEGVCG
Sbjct: 273 QELKEQKKMARKAARFVLRDGALYRRGFSLPLLKCVTPEEGLYILREFHEGVCG 326

The following BLAST results are available for this feature:

BLAST of MC07g_new0003 vs.


Match Name	E-value	Identity	Description

BLAST of MC07g_new0003 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022157610.1	5.37e-57	55.17	uncharacterized protein LOC111024267 [Momordica charantia]	[more]
XP_022158860.1	4.42e-54	54.60	uncharacterized protein LOC111025322 [Momordica charantia]	[more]
XP_022150100.1	5.31e-54	54.60	uncharacterized protein LOC111018362 [Momordica charantia]	[more]
XP_022136647.1	9.89e-54	55.75	uncharacterized protein LOC111008302 [Momordica charantia]	[more]
XP_022151715.1	1.47e-53	53.45	uncharacterized protein LOC111019628 [Momordica charantia]	[more]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1DTK4	2.60e-57	55.17	uncharacterized protein LOC111024267 OS=Momordica charantia OX=3673 GN=LOC111024...	[more]
A0A6J1DX12	2.14e-54	54.60	uncharacterized protein LOC111025322 OS=Momordica charantia OX=3673 GN=LOC111025...	[more]
A0A6J1D7J6	2.57e-54	54.60	Ribonuclease H OS=Momordica charantia OX=3673 GN=LOC111018362 PE=4 SV=1	[more]
A0A6J1C617	4.79e-54	55.75	Ribonuclease H OS=Momordica charantia OX=3673 GN=LOC111008302 PE=4 SV=1	[more]
A0A6J1DBZ0	7.10e-54	53.45	uncharacterized protein LOC111019628 OS=Momordica charantia OX=3673 GN=LOC111019...	[more]

BLAST of MC07g_new0003 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description

InterPro

Analysis Name: InterPro Annotations of Bitter gourd (Dali-11) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036397	Ribonuclease H superfamily	GENE3D	3.30.420.10		coord: 1..79 e-value: 6.0E-15 score: 57.3
IPR002156	Ribonuclease H domain	PFAM	PF13456	RVT_3	coord: 2..70 e-value: 4.0E-8 score: 33.1
None	No IPR available	PANTHER	PTHR46387	POLYNUCLEOTIDYL TRANSFERASE, RIBONUCLEASE H-LIKE SUPERFAMILY PROTEIN	coord: 2..170
None	No IPR available	PANTHER	PTHR46387:SF6	14.7 KDA RIBONUCLEASE H-LIKE PROTEIN	coord: 2..170
IPR012337	Ribonuclease H-like superfamily	SUPERFAMILY	53098	Ribonuclease H-like	coord: 4..75

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MC07g_new0003.1	MC07g_new0003.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0090304	nucleic acid metabolic process
molecular_function	GO:0003676	nucleic acid binding
molecular_function	GO:0004523	RNA-DNA hybrid ribonuclease activity