MC02g1286 (gene) Bitter gourd (Dali-11) v1

Overview
NameMC02g1286
Typegene
OrganismMomordica charantia cv. Dali-11 (Bitter gourd (Dali-11) v1)
DescriptionGamma-secretase subunit PEN-2
LocationMC02: 12605186 .. 12613036 (-)
RNA-Seq ExpressionMC02g1286
SyntenyMC02g1286
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: utr5polypeptideCDSutr3
Hold the cursor over a type above to highlight its positions in the sequence below.
AATTTAAGAAAAGAAAGAAAGAAAGAATAGGAATACGATGAACATTTTGCCTAAAAATTAGTTTCACCACTTCATTTTCTTGGTCACAAAGAGAAAATTCGTTGGTTCCCAATGGAGAGATCGCAGAATCCAAACACGAACCCTAATCCTGTATCGTCGCCGATTGCTGCGTTATGGCCGACAATTGATGCGTCACTGGGGTTGTCCGAGGAAGAGTCCGTGAGCTATGCCCGCGGATTCTACAAATTTGGATTTGCGTTGCTACCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTCCGCGATTCCCACTCGTTTCCTCGCATCCGACCCTGTGAGTTTGCCTCTCTCTGTATCTTTTCGATGAACACGTTTGTACTTTCAATAGTTTCCTTAGTCTACCCTGAGGTGATGTATAAAGAATGATGAATCCGGAATTTACTTTGTTACTGCTGTTCATAGGTGGACATGAATCTGATCATATTGCTGGATTTACCTTAGCTCAATATTTCAAGGATTAGTAGTTGTTTTTCTCGTTCTGTTATAACTCCATTTCTGTATCACATTGATACTCCTCACAACTTGATGGGAAACAATGGATAATAAATTACCGATCCTGTTCATATTCACTAAATTGAGCCTTAAGAATTCAGAAGTGCTTTCTGGATTTCCAATGACAACCTTTCGTTGTAGTGACATAGATATGCATTTTCTGGTGCCTAGGAAGGTGCAAATTCTTGGTTCTTGCTCTCCAAGTGTACAATATTTTTAAATTACCGTAGTTGCTATTCTTTTGAACTTCATCATGCATATCCTTCTTTTTTTGGACAAATTGTACAAACCTATGGTGGTTGTTACAATTGTACTCATAAACAATATTGTTAAACTCATAGAATACACGAGTTGTATTTTATCGACTCACATGCCATGCCCATGATTCAAGTCATGCACTTGAGTCCTAATTTACTAGAATCATCCATTTCAAAATATGAATCATGAGGAACGAAGCAAAGAAATCTTATTAAAAAATTTTATGGAGAGAAGAAGATCCAATCAAATATTTTACATTGTAACATTTCTCTTATACTCTTCTAGACTCATAAGGAAAAAAATAGGAAAAATTTAAAAGAAATCAGAGAAATGAGTGTCATACAAGTTTAGGTGTTGGGAGTCTGGAAGAAGTGAAGCAAGGAGATGTAATATAAGCGTGTGGCATGACAAAGCTGATTGGAAAAAGAATTGAAAGAAAACAGAGAAGGAAGGAGGAAGGAAGAAGAAGTATTGCAAAGACTAGAGGAAGTTAGAGAAACCTGGAGTCTTAACAGATTTATTTTAGTGAAGGGTGACAGTTTTCTAAAGGGAAGGATCTAGACTTACGGTCTTACAATTCACGTGGGTGGATGGGTGGCTTGGATTTGGGGAGTGGGATTGTGCTGTGGAAAGATTACATTTTCCTTGAACAAAATTTAATAATTTAGATAGAGATAATGGACTCCGATTCCTTTCCAAATTTCTATTACCTTCAACAATTTAATATACATATGTGATTTTCTATTTAAATACTAGTCATAAAATAAAACTTATCATACACGCTACGTTAAGATACATGCTAGGCTAAATTTTAATTTGATACATGTTTCGATTCACGAGTTAACATCCTTGCTCAAATTGAACTTTTTGTTTTAGTAAAGAGAAGTGAAGATTCTTGGTTCTTGCTTCCCAACTATACAACATTTTTTAATTTTGGAGTTGGATTGCTTTTCAAGTCATGGTTGCAGTTATTTGAACTTCATTTCCTTTTTTCAGGAAAAAAAGTGTGCATCTACCTGGTTGACCAAGGAGTGTGTGTGCGTGCATGTATTCATGTATGAATTTAATTATATACCAACTAGTGTTTTAAAAAGCTCGAGGCGCACTAAAGCCCAATAGACCTCTGGAGCTTAAGCGCGAGGCGCAAAAAAAAGCGCGGGCTTTTTTTCGCGAGGCGCATTATATATAAAAATAAATAAATATATATACACACACATATAAAACATATAAAAGCCAAATAAGATTAGAAAACATCATAGGTCTTCTCTTAGCATAAAGAATCATGGTCCACAAACTAGTATAAGACTAGAAGTATGATAGTTCGAAATAAAAATCTAAAGATCAAACTCATCATCACTAAATAGTCCTTCAATTTCATCATTTTCATCCTCTCCATCATTAGACTTGTAGCCATCTGCATCTTCCTCCTCGGTGTAATCTTCATCATCAATCAATTGTATGGGTGTGGGCCGTGTGGATTGAGAAGAACTTGAAGCTCCAGCCGTAGTCCTACTTCTTGACCTTGACGTGCTTGCTCTAGAATGATAGGCAGGTTCTTCTGCTCCAGCAGCTCTCGAAACATCACCCCATGTTAAGGAATCATCAACAAATACAAGATCATTATCCTCTTCAGAATCACTATCCATTCTCTCTATCAGCCACTCATTACTATCATCGATATCCTTCAAAGAGATAGGGTCGATTGTGTTCCGCATGTTATGTCGTCGTTTCAATGTTCTATTATACTTTATGAAGACCAAATCATTCAGACGACGTTGTGCAAGTCTATTTCTTTTTTTGCTATGAAGCTGCAAAGTATAAAAGAAAAAAGTCCTATAACAATAATTCTAACCAAGAAGTTAAAAACATATTTATCAAGTGTCAAAGAACTAACCTGTTAAAAAACACTCCAATTCCGTTCACATCCCGATGCACTACAAGTAAAACCGAGAACTCTCATAGCAAACTTCCTCAAGTTTGGAATTGATACTCCAAAATCATCCCACCATTCCACTGTTAAATTGAACTAAACTATGTTAATAATTTTAAACCAAGTAATCAATCAAACATAATAAATCAATACTATTAAAGATTACCTGGAGATCTTTTATTTCTTTGTCTAATCGCCATGGGTTGTTCGAATATTCCTTCGGCGTTCTTGTACTTGGTCATCTCTTGAATTATCTTGTCTTGTATTTCTGAGGAAGGGACCATTCTTGTGACACATGCATACATCCCATTAACAATTTCATCATCTTCAGTAATGTTAGGATTTGAATAGAAGAATTCTGGATTTAGATAATATCCTGCTGCATGCAAAGGACGGTGCAACTGAAGATCCCATCTTTGATTGATGATTTGAAAAACGTCCTTGTATTTGTCTTCCTTACCATTAAAAGATTTAGCAATGGCCTCCTTAGCTCTATCCATGGCCTCATAAATGTATCCCATAGGAGGCTTCTTCTCACCATCCACCAATCTAAGCACTCGAACTAAAGGGCCCGATACTTTAAGAGCAAATACAATTGTATTCCAAAATGATGCCATCAATATTGTCTGAACAACTCGCTTGCCTTGTTGTTCCTTGCTCCATTTGCTATTTTTCCATTCATCAGAAGTAAGCATCTTCCTCAAGTTATTATTCTGATGATGTGTGCTTGATAATGTTATGCAAGTTGTGGCAAGCGAGTCTTAGCTGGCCTAACTAACTCCTTATGATTCGTAAATTGCCTCATCATATTTAACAATCCTGGGCGAACATAAATAAGATTACTGATCTCCATGGCTCGTTTTAGTGTGTTGCGGATATTTCCGATCTTAAATATGTCCTCCAACATCAAGTCCAAGCAATGAGCTGCACATGGTGACCAAAATAAATTTGGTCGTTTTGCTTCTAATAATCTCCCTAGTAACAAAATAAAATAAAAAAGATAACATATTAGCCTACTTGAAATGTTTAACTAACATAAGACTAATTTGTAGAGAAGCAAGGAATTTGATTTCTTACCCGCCAACACATTTGCTGAAGCACTATCAGTAACGACGTGTGCGACATTGGCTTCTCCAATGCGCTCGACAAAATCATCAAGTAACTCAAACATTTTCTTCCCGTTCTTTACATAAGATGAAGCATCAATGGACTCAATAAACATTGTGCCTTTAGGACTATTAACTAAAAAGTTAATTAATGTCCTCTCTCTCCTATCGGTCCTCCATCCATCGGCCATGATAGTACATCCAACCTTGGCCCACTCTTCCTTGTGACTCTTCATCAATCCATGTGTTGCTTCTAAATCCTTTTTCAACAACGGCACTCTAAGCTCATAATAATATGGTATTTTTAGTCCAGGACCGAATTGTCCTATTGCTTCAACCATAGGAGCAAAGCTTTCAGAATTGATAGCATTCAAAGGAATTCCAGAATCATAAAACCATCGTGCAATTCTTTGAACTGTGCACTCCCTTATTTCCTTTTTGTAAGCTTCATTGAGTGTTGTTTGTTTGCCTTTCTCATTCTTTCGATTCAGAACTACCGACTCTGGATTAGGAGTAAAAAATGCATCAATTGAACCTTTCTGCCTTGGCTTCTTAGGGTCTAAACTTGGCCTTTGACTACAAGGTCTCTTACTCGAACTAGTTATAATCAAATCATCCTCATCTTCATCATCCATACCAAAATCTTGATCATCAATATCAGGTATAAGATTTCTTTGTTCTTTGATCTCTTTCTTCTTGGACATGTGCTCCCTAATTTCTTCCTTCACATGATCCGAACATTTCTTGCATGCGGTTGTATTTCTATAACCACCAACAAGGTGTCGTTTCACCCTATAAACTCCTCCTTTTGTGACTTTTGAACAAAAACTACATTAAAAGTAGTCAAATCTTGAGGATTTGCCAAAGTAGCATACTTCCATGCCGGATCTTTTCTTGGGCCTTCATTAGACATCTATGTAAAATTGTAATCAATAGAAAAAAAAACAGAATATTAGAAGGACGGAGCTTACTGTTTTGGATTGGAGAAATTGAAGAAAATAGTGTTGGATTGGAGAAATAGAAAGTGAAGAAGGGATAGAGAAATAGCTTACTGTCTGTAACTTTGTTGGAGTGGAGAAATAGAAATTGAATACTATAACTTTGTTGTTGGAGGTTGTTGGAGCTTGCTGTTTTGGATTAGAATAGAAACAGAGGGAAAGATATGCACTTTCCATTGGATTGGAGAATTAAAAAATTAGAAATAAAGATAGAGAAAAGAATAGAAATAGAGAGAGAGCTTACAAATGGAGGGGGAGAGTTGCTCACAGTCACAGAGTCAGCGGCACCGCTCATGCAACCACGGGCGGCCGGCCACAGGAGATACAGAGAGAGACAGAGAGTGTCAAAATCGAAATAGAGAGAGAGAGATGCAGTGAAAGTCGAAAATCGAAATAGAGGGAGAAGAAGAACTAAGTGTCTGTTGAGTTTTTTACGTGCATGGGAAGGAAAGGAAGAAGACGATACAGTTGAGATTCTTTCCATTTAAAAAAAAAAATCAAATTAAGATTGGAAATCGGAAAAGGCGTGCGGCGGTTATCATTCTACTCATTCCATTTAATTAAATAGTTCTGCATTTAGGGTCTGTACGTTTTATTTTTTATTTTTAAAAACAGAGCCCATGAAGCCCGCGCTTCATAGGCTTAGAATTTTCTAACGAGGCGCGCGCAAAGCGCGCGCCTCATTCAGATCGCCTCGCCTTGAAAAGGCGAGGCGCAATAGGTGGGCATAATGCCTAGGCGCGCCTTTTAAAACACTGATACCAACTAGGACAATAAGGGTGGTTTTGTGTGTGTTGTGTGTAATAAGGGTGGTTTTTTGTGTGTTAATGAGAAACTCTCAGAAAGGGCCAATCTTAAACGTGGTTTATTATTTGTTGAATGCATCAACAACCCTTTGTTTTTATGTATCTCCTTGGTGGTGGTAATGGCATTGGTTTTGGAGATACCTTTCAAGGCCATAGGTTCAAGCGCTCCACTTGAGAACTTAATAACATAAAACGCTTAATGTTTTTCAGACTTGGCCTTGAGGTGGACTAAGTCTTCTTGAGAGTTATTCGGGTGGGCATTGAGGATAAGGCAAGGAGTGGGCTCTTGACACCTTGGTTACCATTTTCTCCCTTCTATTTCATAGTTACACTGACTTATCCAAGGTTCATGAGTTAGAGTGATTAAAAGTTATTCTCCACCTGTTGTTTCTTGTGGTTTAAATTATTCAATCTCATTCTTATTTGATAAAAGATCTCAATAAATTGATTCCAAGATAATGCAGAGAAGTTGTTTATATGAAGGAAAATTGTTTTATAGTAGAATTTATAGTTGTACTGCAATTACGAATTAATTAGTGCAATAACGAATCTATAGTTCATAGTTGTACCGAAATAATGAAATCAATTTGAGATTAACACTGTCAACACTCAAAGGCTTCTCTTTTGGTCACTATAACTCGGAAATCCACGACACTTCTCTTGCATGACTATGTTTATTTCATTCGTAATTTGGATTCTAGTCCATATTCTTTCGGAACAAATTATGGTAGTCCAACATGTCTAAGAAAGGTGAGTTCTTTCTTTGGTTTATTTAGTATGAAAGCTTTGACACTTGGACAAAGTTTAGAATTTTGATTTTTCTCTTTTCATGAACGGGTGTCCCTGTAATGGAAATGGTGGGGATCAAAGCCATATGATGATCTACTGAACTTTAGCATGGGTATATGGTGCAGCATTCTGGATCTTTTCAACCTAAAGTGGTACCCTGGGGAGTCCTGTCTTTTGATTCTCTTACTGTAGTTCTTCTCTCTTTTCACTCCTTTAGGAGTTTATATCTTTGAACAATTTTGTTCCTTTTCATTTCATTTCTCAATAAAAAGATCGTATTTTGTTAAAAAGAAAAAAAATATATGTGACTGAAGGTTTACTTTCACCTTATTGATTAGTCCTGACATAATACAATGCTTTGGTATGCTCTAATCAGTTTACTTTTGAATTTTGATGTTTTCCCCCGTTTTTCTTGCTTTATGTAACCATGGTAGTGTTAGTGTTAACTTTTTTCTTTTACAAAGTTCGATAAGGCATTTGTTTCCGTTGACTTTGAGTTATTCCCTGTTAGGTTAAGAGATCTGTGAGAAATTCACTGATATTATTTTCCCCCATAAAAACCTGGGTTTGGTGCTTGAAAATTTTATCTAACGATTTGAAATTGTTCTTCCTTTTAGATATTGTTGGGTCAGCTATTGGGTTTGCTGTTTTCATGGCCATTCTTTCCTCTTGGGCCTTGACATTTGCCATTGGAGGGGAACGTCTCTTTGGACCTGTTTGGGATAAACTTGTGATGTATAACGTTGCTGACAAATTAGGATTGACAGGTTGGAACTAGTTTGGTTCCTTCCTTTCAGCAACTAATCTCGTTCTCGTTTTTGTATATTTCAAAATGTATAACTTTCTACTGTCAATTCTTTGCCCTTAAGATCAAAGTTGAAGCATCTGGTTTTACTTCTCCAAGTGATATAAGGTTCAAACATAAACTTAGTTATAACAGGGATTTCAGATTTAAACATAATTGAGACGAAAAGTCTGGGGTTAAACTGACATAAATTGTTTAAACAACACTTGAATTTGCATTGTCACACCGATGCTTGATGGTGATGCTGATTATCAGTAAATTCATGAATTTGAATGGGCTCTCCCTTCTGAGCTTTGTGGATTCCTTTGCTTCCATTATAGAAACTGTGCTTTCTTTTCTGGTTTCCCTACTTGCGTACATTCGTTTTTCAGGTCAAAATAGAAGGGACTATTCAGAATGCATCACCAAGCGCGAAAAAACGTACGATGGTATAAAAGAAAACTTACAACAGGGAGATTTTAGTAGGATATTGTTGTATTGTATTCCCAATTTCAGACACATATCTGTTAGTGTTGATTCTCTCTATAAGATAGCATTGAAAGAAGTTTGTTTTGAAATGCTACTTTTGGATGATTTTCCCTGGCAGAGTAAGCTGTGA

mRNA sequence

AATTTAAGAAAAGAAAGAAAGAAAGAATAGGAATACGATGAACATTTTGCCTAAAAATTAGTTTCACCACTTCATTTTCTTGGTCACAAAGAGAAAATTCGTTGGTTCCCAATGGAGAGATCGCAGAATCCAAACACGAACCCTAATCCTGTATCGTCGCCGATTGCTGCGTTATGGCCGACAATTGATGCGTCACTGGGGTTGTCCGAGGAAGAGTCCGTGAGCTATGCCCGCGGATTCTACAAATTTGGATTTGCGTTGCTACCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTCCGCGATTCCCACTCGTTTCCTCGCATCCGACCCTATATTGTTGGGTCAGCTATTGGGTTTGCTGTTTTCATGGCCATTCTTTCCTCTTGGGCCTTGACATTTGCCATTGGAGGGGAACGTCTCTTTGGACCTGTTTGGGATAAACTTGTGATGTATAACGTTGCTGACAAATTAGGATTGACAGGTTGGAACTAGTTTGGTTCCTTCCTTTCAGCAACTAATCTCGTTCTCGTTTTTGTATATTTCAAAATGTATAACTTTCTACTGTCAATTCTTTGCCCTTAAGATCAAAGTTGAAGCATCTGGTTTTACTTCTCCAAGTGATATAAGGTTCAAACATAAACTTAGTTATAACAGGGATTTCAGATTTAAACATAATTGAGACGAAAAGTCTGGGGTTAAACTGACATAAATTGTTTAAACAACACTTGAATTTGCATTGTCACACCGATGCTTGATGGTGATGCTGATTATCAGTAAATTCATGAATTTGAATGGGCTCTCCCTTCTGAGCTTTGTGGATTCCTTTGCTTCCATTATAGAAACTGTGCTTTCTTTTCTGGTTTCCCTACTTGCGTACATTCGTTTTTCAGGTCAAAATAGAAGGGACTATTCAGAATGCATCACCAAGCGCGAAAAAACGTACGATGGTATAAAAGAAAACTTACAACAGGGAGATTTTAGTAGGATATTGTTGTATTGTATTCCCAATTTCAGACACATATCTGTTAGTGTTGATTCTCTCTATAAGATAGCATTGAAAGAAGTTTGTTTTGAAATGCTACTTTTGGATGATTTTCCCTGGCAGAGTAAGCTGTGA

Coding sequence (CDS)

ATGGAGAGATCGCAGAATCCAAACACGAACCCTAATCCTGTATCGTCGCCGATTGCTGCGTTATGGCCGACAATTGATGCGTCACTGGGGTTGTCCGAGGAAGAGTCCGTGAGCTATGCCCGCGGATTCTACAAATTTGGATTTGCGTTGCTACCATTTCTTTGGGCGGTTAATTGCTTCTACTTCTGGCCTGTTCTCCGCGATTCCCACTCGTTTCCTCGCATCCGACCCTATATTGTTGGGTCAGCTATTGGGTTTGCTGTTTTCATGGCCATTCTTTCCTCTTGGGCCTTGACATTTGCCATTGGAGGGGAACGTCTCTTTGGACCTGTTTGGGATAAACTTGTGATGTATAACGTTGCTGACAAATTAGGATTGACAGGTTGGAACTAG

Protein sequence

MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNVADKLGLTGWN
Homology
BLAST of MC02g1286 vs. ExPASy Swiss-Prot
Match: Q9FY84 (Probable gamma-secretase subunit PEN-2 OS=Arabidopsis thaliana OX=3702 GN=At5g09310 PE=2 SV=1)

HSP 1 Score: 197.6 bits (501), Expect = 8.7e-50
Identity = 93/128 (72.66%), Postives = 111/128 (86.72%), Query Frame = 0

Query: 3   RSQNPNTNPNPVSSPI--AALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 62
           R+ NPN NPNP+S+ I  A +WPTID  LGL+EE SV YAR FYKFGFALLP+LW VNCF
Sbjct: 17  RNPNPNPNPNPLSTIISSAQVWPTIDGPLGLTEEASVDYARRFYKFGFALLPWLWFVNCF 76

Query: 63  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 122
           YFWPVLR S +FP+IR Y+V SAIGF+VF A+LS+WALTF+IGGE+LFGP++DKLVMYNV
Sbjct: 77  YFWPVLRHSRAFPQIRNYVVRSAIGFSVFTALLSAWALTFSIGGEQLFGPLYDKLVMYNV 136

Query: 123 ADKLGLTG 129
           AD+LGL+G
Sbjct: 137 ADRLGLSG 144

BLAST of MC02g1286 vs. ExPASy Swiss-Prot
Match: Q5G235 (Gamma-secretase subunit PEN-2 OS=Bos taurus OX=9913 GN=PSENEN PE=3 SV=1)

HSP 1 Score: 58.2 bits (139), Expect = 8.3e-08
Identity = 33/94 (35.11%), Postives = 53/94 (56.38%), Query Frame = 0

Query: 31  LSEEESVSYARGFYKFGFALLPFLWAVNCFYFWPVLRDSHSFP------RIRPYIVGSAI 90
           +S EE ++  R +Y  GFA LPFLW VN F+F+   R++   P      +I+ Y+  SA+
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFF---REAFIVPAYTEQSQIKGYVWRSAV 65

Query: 91  GFAVFMAILSSWALTFAIGGERLFGPVWDKLVMY 119
           GF +++ +LS+W   F     +++ P W  L  Y
Sbjct: 66  GFFLWVIVLSTWITIF-----QIYRPRWGALGDY 91

BLAST of MC02g1286 vs. ExPASy Swiss-Prot
Match: Q9NZ42 (Gamma-secretase subunit PEN-2 OS=Homo sapiens OX=9606 GN=PSENEN PE=1 SV=1)

HSP 1 Score: 57.8 bits (138), Expect = 1.1e-07
Identity = 33/94 (35.11%), Postives = 52/94 (55.32%), Query Frame = 0

Query: 31  LSEEESVSYARGFYKFGFALLPFLWAVNCFYFWPVLRDSHSFP------RIRPYIVGSAI 90
           +S EE ++  R +Y  GFA LPFLW VN F+F+   R++   P      +I+ Y+  SA+
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFF---REAFLVPAYTEQSQIKGYVWRSAV 65

Query: 91  GFAVFMAILSSWALTFAIGGERLFGPVWDKLVMY 119
           GF  ++ +L+SW   F     +++ P W  L  Y
Sbjct: 66  GFLFWVIVLTSWITIF-----QIYRPRWGALGDY 91

BLAST of MC02g1286 vs. ExPASy Swiss-Prot
Match: Q9CQR7 (Gamma-secretase subunit PEN-2 OS=Mus musculus OX=10090 GN=Psenen PE=1 SV=1)

HSP 1 Score: 56.6 bits (135), Expect = 2.4e-07
Identity = 33/94 (35.11%), Postives = 52/94 (55.32%), Query Frame = 0

Query: 31  LSEEESVSYARGFYKFGFALLPFLWAVNCFYFWPVLRDSHSFP------RIRPYIVGSAI 90
           +S EE ++  R +Y  GFA LPFLW VN F+F+   R++   P      +I+ Y+  SA+
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFF---REAFLAPAYTEQSQIKGYVWRSAV 65

Query: 91  GFAVFMAILSSWALTFAIGGERLFGPVWDKLVMY 119
           GF  ++ IL++W   F     +++ P W  L  Y
Sbjct: 66  GFLFWVIILATWITIF-----QIYRPRWGALGDY 91

BLAST of MC02g1286 vs. ExPASy Swiss-Prot
Match: Q6QI68 (Gamma-secretase subunit PEN-2 OS=Rattus norvegicus OX=10116 GN=Psenen PE=3 SV=1)

HSP 1 Score: 55.8 bits (133), Expect = 4.1e-07
Identity = 30/91 (32.97%), Postives = 51/91 (56.04%), Query Frame = 0

Query: 31  LSEEESVSYARGFYKFGFALLPFLWAVNCFYFWPVLRDSHSF---PRIRPYIVGSAIGFA 90
           +S EE ++  R +Y  GFA LPFLW VN F+F+     + ++    +I+ Y+  SA+GF 
Sbjct: 6   VSNEEKLNLCRKYYLGGFAFLPFLWLVNIFWFFKEAFFAPAYTEQSQIKGYVWRSAVGFL 65

Query: 91  VFMAILSSWALTFAIGGERLFGPVWDKLVMY 119
            ++ +L++W   F     +++ P W  L  Y
Sbjct: 66  FWVIVLTTWITIF-----QIYRPRWGALGDY 91

BLAST of MC02g1286 vs. NCBI nr
Match: XP_022156680.1 (probable gamma-secretase subunit PEN-2 [Momordica charantia])

HSP 1 Score: 275 bits (703), Expect = 2.36e-93
Identity = 130/130 (100.00%), Postives = 130/130 (100.00%), Query Frame = 0

Query: 1   MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 60
           MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF
Sbjct: 1   MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 60

Query: 61  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 120
           YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV
Sbjct: 61  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 120

Query: 121 ADKLGLTGWN 130
           ADKLGLTGWN
Sbjct: 121 ADKLGLTGWN 130

BLAST of MC02g1286 vs. NCBI nr
Match: XP_022946973.1 (probable gamma-secretase subunit PEN-2 [Cucurbita moschata] >KAG7035284.1 putative gamma-secretase subunit PEN-2 [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 252 bits (643), Expect = 4.38e-84
Identity = 121/138 (87.68%), Postives = 127/138 (92.03%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQNPNTNPN        PVSS IAALWPTIDASLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MESSQNPNTNPNSNPNRIQNPVSSQIAALWPTIDASLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFA+FMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAIFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           +KLVMYN+ADKLGLTGW+
Sbjct: 121 NKLVMYNLADKLGLTGWS 138

BLAST of MC02g1286 vs. NCBI nr
Match: XP_023532347.1 (probable gamma-secretase subunit PEN-2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 248 bits (633), Expect = 1.47e-82
Identity = 119/138 (86.23%), Postives = 125/138 (90.58%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME S NPNTNPN        PVSS IAALWPTID SLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MESSPNPNTNPNSNPTRIQNPVSSQIAALWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFA+FMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAIFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           +KLVMYN+ADKLGLTGW+
Sbjct: 121 NKLVMYNLADKLGLTGWS 138

BLAST of MC02g1286 vs. NCBI nr
Match: XP_023007265.1 (probable gamma-secretase subunit PEN-2 [Cucurbita maxima])

HSP 1 Score: 246 bits (628), Expect = 8.50e-82
Identity = 120/138 (86.96%), Postives = 125/138 (90.58%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQNPNT PN        PVSS IAALWPTIDASLGLS EESVSYAR FYKFGFALLP
Sbjct: 1   MESSQNPNTIPNSNPNRIQNPVSSQIAALWPTIDASLGLSGEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           +KLVMYN+ADKLGLTGW+
Sbjct: 121 NKLVMYNLADKLGLTGWS 138

BLAST of MC02g1286 vs. NCBI nr
Match: KAG6605326.1 (putative gamma-secretase subunit PEN-2, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 245 bits (625), Expect = 3.29e-81
Identity = 119/135 (88.15%), Postives = 124/135 (91.85%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQNPNTNPN        PVSS IAALWPTIDASLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MESSQNPNTNPNSNPNRIQNPVSSQIAALWPTIDASLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFA+FMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAIFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLT 127
           +KLVMYN+ADKLGLT
Sbjct: 121 NKLVMYNLADKLGLT 135

BLAST of MC02g1286 vs. ExPASy TrEMBL
Match: A0A6J1DR09 (probable gamma-secretase subunit PEN-2 OS=Momordica charantia OX=3673 GN=LOC111023529 PE=3 SV=1)

HSP 1 Score: 275 bits (703), Expect = 1.14e-93
Identity = 130/130 (100.00%), Postives = 130/130 (100.00%), Query Frame = 0

Query: 1   MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 60
           MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF
Sbjct: 1   MERSQNPNTNPNPVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 60

Query: 61  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 120
           YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV
Sbjct: 61  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 120

Query: 121 ADKLGLTGWN 130
           ADKLGLTGWN
Sbjct: 121 ADKLGLTGWN 130

BLAST of MC02g1286 vs. ExPASy TrEMBL
Match: A0A6J1G5B2 (probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC111450992 PE=3 SV=1)

HSP 1 Score: 252 bits (643), Expect = 2.12e-84
Identity = 121/138 (87.68%), Postives = 127/138 (92.03%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQNPNTNPN        PVSS IAALWPTIDASLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MESSQNPNTNPNSNPNRIQNPVSSQIAALWPTIDASLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFA+FMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAIFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           +KLVMYN+ADKLGLTGW+
Sbjct: 121 NKLVMYNLADKLGLTGWS 138

BLAST of MC02g1286 vs. ExPASy TrEMBL
Match: A0A6J1L2H7 (probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC111499803 PE=3 SV=1)

HSP 1 Score: 246 bits (628), Expect = 4.11e-82
Identity = 120/138 (86.96%), Postives = 125/138 (90.58%), Query Frame = 0

Query: 1   MERSQNPNTNPN--------PVSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQNPNT PN        PVSS IAALWPTIDASLGLS EESVSYAR FYKFGFALLP
Sbjct: 1   MESSQNPNTIPNSNPNRIQNPVSSQIAALWPTIDASLGLSGEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAI+SSWALTF+IGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAIISSWALTFSIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           +KLVMYN+ADKLGLTGW+
Sbjct: 121 NKLVMYNLADKLGLTGWS 138

BLAST of MC02g1286 vs. ExPASy TrEMBL
Match: A0A6J1F097 (probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC111438306 PE=3 SV=1)

HSP 1 Score: 244 bits (622), Expect = 3.27e-81
Identity = 120/138 (86.96%), Postives = 124/138 (89.86%), Query Frame = 0

Query: 1   MERSQNPNTNPNP--------VSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQN N+NPNP        VSSPIA LWPTID SLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MENSQNSNSNPNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLR SHSFPRIRPYIVGSAIGFAVFMAI+SSWALTFAIGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLR-SHSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           DKLVMYN+ADKLGLTGW+
Sbjct: 121 DKLVMYNLADKLGLTGWS 137

BLAST of MC02g1286 vs. ExPASy TrEMBL
Match: A0A6J1I943 (probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC111470312 PE=3 SV=1)

HSP 1 Score: 237 bits (604), Expect = 1.82e-78
Identity = 118/138 (85.51%), Postives = 122/138 (88.41%), Query Frame = 0

Query: 1   MERSQNPNTNPNP--------VSSPIAALWPTIDASLGLSEEESVSYARGFYKFGFALLP 60
           ME SQN N+N NP        VSSPIA LWPTID SLGLSEEESVSYAR FYKFGFALLP
Sbjct: 1   MENSQNSNSNLNPNPIRIQNLVSSPIAVLWPTIDGSLGLSEEESVSYARRFYKFGFALLP 60

Query: 61  FLWAVNCFYFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVW 120
           FLWAVNCFYFWPVLR S SFPRIRPYIVGSAIGFAVFMAI+SSWALTFAIGGERLFGPVW
Sbjct: 61  FLWAVNCFYFWPVLR-SRSFPRIRPYIVGSAIGFAVFMAIISSWALTFAIGGERLFGPVW 120

Query: 121 DKLVMYNVADKLGLTGWN 130
           DKLVMYN+ADKLGLTGW+
Sbjct: 121 DKLVMYNLADKLGLTGWS 137

BLAST of MC02g1286 vs. TAIR 10
Match: AT5G09310.1 (CONTAINS InterPro DOMAIN/s: Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunit (InterPro:IPR019379); Has 168 Blast hits to 168 proteins in 71 species: Archae - 0; Bacteria - 0; Metazoa - 126; Fungi - 0; Plants - 36; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink). )

HSP 1 Score: 197.6 bits (501), Expect = 6.2e-51
Identity = 93/128 (72.66%), Postives = 111/128 (86.72%), Query Frame = 0

Query: 3   RSQNPNTNPNPVSSPI--AALWPTIDASLGLSEEESVSYARGFYKFGFALLPFLWAVNCF 62
           R+ NPN NPNP+S+ I  A +WPTID  LGL+EE SV YAR FYKFGFALLP+LW VNCF
Sbjct: 17  RNPNPNPNPNPLSTIISSAQVWPTIDGPLGLTEEASVDYARRFYKFGFALLPWLWFVNCF 76

Query: 63  YFWPVLRDSHSFPRIRPYIVGSAIGFAVFMAILSSWALTFAIGGERLFGPVWDKLVMYNV 122
           YFWPVLR S +FP+IR Y+V SAIGF+VF A+LS+WALTF+IGGE+LFGP++DKLVMYNV
Sbjct: 77  YFWPVLRHSRAFPQIRNYVVRSAIGFSVFTALLSAWALTFSIGGEQLFGPLYDKLVMYNV 136

Query: 123 ADKLGLTG 129
           AD+LGL+G
Sbjct: 137 ADRLGLSG 144

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q9FY848.7e-5072.66Probable gamma-secretase subunit PEN-2 OS=Arabidopsis thaliana OX=3702 GN=At5g09... [more]
Q5G2358.3e-0835.11Gamma-secretase subunit PEN-2 OS=Bos taurus OX=9913 GN=PSENEN PE=3 SV=1[more]
Q9NZ421.1e-0735.11Gamma-secretase subunit PEN-2 OS=Homo sapiens OX=9606 GN=PSENEN PE=1 SV=1[more]
Q9CQR72.4e-0735.11Gamma-secretase subunit PEN-2 OS=Mus musculus OX=10090 GN=Psenen PE=1 SV=1[more]
Q6QI684.1e-0732.97Gamma-secretase subunit PEN-2 OS=Rattus norvegicus OX=10116 GN=Psenen PE=3 SV=1[more]
Match NameE-valueIdentityDescription
XP_022156680.12.36e-93100.00probable gamma-secretase subunit PEN-2 [Momordica charantia][more]
XP_022946973.14.38e-8487.68probable gamma-secretase subunit PEN-2 [Cucurbita moschata] >KAG7035284.1 putati... [more]
XP_023532347.11.47e-8286.23probable gamma-secretase subunit PEN-2 [Cucurbita pepo subsp. pepo][more]
XP_023007265.18.50e-8286.96probable gamma-secretase subunit PEN-2 [Cucurbita maxima][more]
KAG6605326.13.29e-8188.15putative gamma-secretase subunit PEN-2, partial [Cucurbita argyrosperma subsp. s... [more]
Match NameE-valueIdentityDescription
A0A6J1DR091.14e-93100.00probable gamma-secretase subunit PEN-2 OS=Momordica charantia OX=3673 GN=LOC1110... [more]
A0A6J1G5B22.12e-8487.68probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC11145... [more]
A0A6J1L2H74.11e-8286.96probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC1114998... [more]
A0A6J1F0973.27e-8186.96probable gamma-secretase subunit PEN-2 OS=Cucurbita moschata OX=3662 GN=LOC11143... [more]
A0A6J1I9431.82e-7885.51probable gamma-secretase subunit PEN-2 OS=Cucurbita maxima OX=3661 GN=LOC1114703... [more]
Match NameE-valueIdentityDescription
AT5G09310.16.2e-5172.66CONTAINS InterPro DOMAIN/s: Gamma-secretase aspartyl protease complex, presenili... [more]
InterPro
Analysis Name: InterPro Annotations of Bitter gourd (Dali-11) v1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR019379Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunitPFAMPF10251PEN-2coord: 33..121
e-value: 1.6E-29
score: 102.1
IPR019379Gamma-secretase aspartyl protease complex, presenilin enhancer-2 subunitPANTHERPTHR16318GAMMA-SECRETASE SUBUNIT PEN-2coord: 7..129

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
MC02g1286.1MC02g1286.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007219 Notch signaling pathway
biological_process GO:0006508 proteolysis
cellular_component GO:0070765 gamma-secretase complex
cellular_component GO:0005798 Golgi-associated vesicle
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0008233 peptidase activity