Lag0038097 (gene) Sponge gourd (AG‐4) v1

Overview
NameLag0038097
Typegene
OrganismLuffa acutangula (Sponge gourd (AG‐4) v1)
DescriptionSodium/hydrogen exchanger
Locationchr2: 12531968 .. 12532766 (-)
RNA-Seq ExpressionLag0038097
SyntenyLag0038097
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGATCACATTTAAACAACAGGTCGGTATCTCTTTGTGAATGTTACACCACAACTTTTTAGCATGGAATCATGGGAACTACATTGATATCACTGATCTATGAACTGGTGAAATTTTACAGATCATAATATGGTGGGCTGGGCTAATGAGAGGAGCTGTGTCCATTGCTCTGGCTTTCAAACAGGTGAGTCTTTCTTTCTGATTAGAACTGTTCATAGATGCACTTCTGGAGTAAATCATTTTCTGATTTATGGGCACCATATCTATTGAACGTGAAAATGTTTGTGTATTTTGAAGTTCACTTATTCTGGGGTTACATTGGATCCCACCAACGCAACAATGATTACCATCACCACAGTTGTTGTACTCTTCACTACGGTGGTACGTGTTCGATCTTCTTGATATGTATGTTATTCTTTTAATCTAATTATTCTATGGCATGGGCTCATCACTTAATAATTTGTCATGAATGGTCTATAGCATCAATACACTTTTATCAAATTCAGGTATTTGGGTTTCTAACAAAGCCACTCATAAGATGTCTGCTTCCTCCCAACCAAGCAACTAATAATGCAAACAATTCCACTCCGAAGTTCACCGAAGAGGACATAACTCTCCCTTTGCTCTCCATGGAAGAGTCTGCTGCAACCAATGTCCTCCGTGCAAAGGATAGTTTGTCGATGTTGATAGAGAGGCCTGTTTATACCATACATTTCTTTTGGAGGAAATTTGATGATACCTACATGAGGCCTATATTTGGAGGGCCTCGCAACAACCAACCTGGTGGTTCTCGTTGTTAA

mRNA sequence

ATGATCACATTTAAACAACAGATCATAATATGGTGGGCTGGGCTAATGAGAGGAGCTGTGTCCATTGCTCTGGCTTTCAAACAGTTCACTTATTCTGGGGTTACATTGGATCCCACCAACGCAACAATGATTACCATCACCACAGTTGTTGTACTCTTCACTACGGTGGTATTTGGGTTTCTAACAAAGCCACTCATAAGATGTCTGCTTCCTCCCAACCAAGCAACTAATAATGCAAACAATTCCACTCCGAAGTTCACCGAAGAGGACATAACTCTCCCTTTGCTCTCCATGGAAGAGTCTGCTGCAACCAATGTCCTCCGTGCAAAGGATAGTTTGTCGATGTTGATAGAGAGGCCTGTTTATACCATACATTTCTTTTGGAGGAAATTTGATGATACCTACATGAGGCCTATATTTGGAGGGCCTCGCAACAACCAACCTGGTGGTTCTCGTTGTTAA

Coding sequence (CDS)

ATGATCACATTTAAACAACAGATCATAATATGGTGGGCTGGGCTAATGAGAGGAGCTGTGTCCATTGCTCTGGCTTTCAAACAGTTCACTTATTCTGGGGTTACATTGGATCCCACCAACGCAACAATGATTACCATCACCACAGTTGTTGTACTCTTCACTACGGTGGTATTTGGGTTTCTAACAAAGCCACTCATAAGATGTCTGCTTCCTCCCAACCAAGCAACTAATAATGCAAACAATTCCACTCCGAAGTTCACCGAAGAGGACATAACTCTCCCTTTGCTCTCCATGGAAGAGTCTGCTGCAACCAATGTCCTCCGTGCAAAGGATAGTTTGTCGATGTTGATAGAGAGGCCTGTTTATACCATACATTTCTTTTGGAGGAAATTTGATGATACCTACATGAGGCCTATATTTGGAGGGCCTCGCAACAACCAACCTGGTGGTTCTCGTTGTTAA

Protein sequence

MITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFLTKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERPVYTIHFFWRKFDDTYMRPIFGGPRNNQPGGSRC
Homology
[Close]
BLAST of Lag0038097 vs. NCBI nr
Match: XP_022940663.1 (sodium/hydrogen exchanger 4 [Cucurbita moschata])

HSP 1 Score: 274.6 bits (701), Expect = 5.1e-70
Identity = 141/154 (91.56%), Postives = 147/154 (95.45%), Query Frame = 0 

Query: 1   MITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGF 60
           +ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVT DPT+ATMITITTVVVLFTTVVFGF
Sbjct: 376 IITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTRDPTHATMITITTVVVLFTTVVFGF 435

Query: 61  LTKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP 120
           LTKPLIRCLLP NQATN+A+NS PKFTEEDITLPLLSMEESAATNVLRAKDSLSML+ERP
Sbjct: 436 LTKPLIRCLLPLNQATNSASNSGPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLMERP 495

Query: 121 VYTIHFFWRKFDDTYMRPIFGGP-RNNQPGGSRC 154
           VYTIHFFWRKFDD YMRPIFGGP R+NQP GS C
Sbjct: 496 VYTIHFFWRKFDDYYMRPIFGGPRRSNQPSGSGC 529

[Close]
BLAST of Lag0038097 vs. NCBI nr
Match: XP_023522086.1 (sodium/hydrogen exchanger 4 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 272.7 bits (696), Expect = 1.9e-69
Identity = 140/154 (90.91%), Postives = 146/154 (94.81%), Query Frame = 0 

Query: 1   MITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGF 60
           +ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVT DPT+ATMITITTVVVLFTTVVFGF
Sbjct: 376 IITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTRDPTHATMITITTVVVLFTTVVFGF 435

Query: 61  LTKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP 120
           LTKPLIRCLLP NQATN+A+NS PKFTEEDITLPLLSMEESAATNVLRAKDSLSML+ERP
Sbjct: 436 LTKPLIRCLLPLNQATNSASNSGPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLMERP 495

Query: 121 VYTIHFFWRKFDDTYMRPIFGGP-RNNQPGGSRC 154
           VYTIHFFWRKFDD YMRPIFGGP  +NQP GS C
Sbjct: 496 VYTIHFFWRKFDDYYMRPIFGGPCHSNQPSGSGC 529

[Close]
BLAST of Lag0038097 vs. NCBI nr
Match: XP_038897275.1 (sodium/hydrogen exchanger 4 [Benincasa hispida])

HSP 1 Score: 271.2 bits (692), Expect = 5.6e-69
Identity = 135/154 (87.66%), Postives = 148/154 (96.10%), Query Frame = 0 

Query: 1   MITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGF 60
           MI+FKQQIIIWWAGLMRGAVSIALAFKQFTYSGVT+DPT+ATMIT TT+VVLFTTVVFGF
Sbjct: 376 MISFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTVDPTHATMITNTTIVVLFTTVVFGF 435

Query: 61  LTKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP 120
           LTKPLIRCL+PPNQA+++ +N  PKFTE+DITLPLLSMEESAATNVLRAKDSLSMLIERP
Sbjct: 436 LTKPLIRCLIPPNQASSSTSNPRPKFTEDDITLPLLSMEESAATNVLRAKDSLSMLIERP 495

Query: 121 VYTIHFFWRKFDDTYMRPIFGGPRNNQ-PGGSRC 154
           V+TIHFFWRKFDD+YMRPIFGGPR+NQ PGGS C
Sbjct: 496 VFTIHFFWRKFDDSYMRPIFGGPRHNQPPGGSGC 529

[Close]
BLAST of Lag0038097 vs. NCBI nr
Match: XP_022139522.1 (sodium/hydrogen exchanger 4 [Momordica charantia])

HSP 1 Score: 270.8 bits (691), Expect = 7.3e-69
Identity = 139/158 (87.97%), Postives = 144/158 (91.14%), Query Frame = 0 

Query: 2   ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFL 61
           ITF+QQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPT+A MIT TTVVVLFTTVVFGFL
Sbjct: 376 ITFRQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTHAAMITNTTVVVLFTTVVFGFL 435

Query: 62  TKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERPV 121
           TKPLIRCLLP NQ TN A+NS PKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERPV
Sbjct: 436 TKPLIRCLLPHNQETNRASNSGPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERPV 495

Query: 122 YTIHFFWRKFDDTYMRPIFGGP------RNNQPGGSRC 154
           YTIH+FWRKFDDTYMRP+FGGP      RNNQP  SRC
Sbjct: 496 YTIHYFWRKFDDTYMRPLFGGPHNNQPSRNNQPSHSRC 533

[Close]
BLAST of Lag0038097 vs. NCBI nr
Match: TYK08093.1 (sodium/hydrogen exchanger 4 [Cucumis melo var. makuwa])

HSP 1 Score: 270.8 bits (691), Expect = 7.3e-69
Identity = 136/154 (88.31%), Postives = 147/154 (95.45%), Query Frame = 0 

Query: 1   MITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGF 60
           MI+FKQQIIIWWAGLMRGAVSIALAFKQFTYSGVT+DP +ATMIT TT+VVLFTTVVFGF
Sbjct: 283 MISFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTVDPIHATMITNTTIVVLFTTVVFGF 342

Query: 61  LTKPLIRCLLPPNQATNNANNSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP 120
           LTKPLI CLLPPNQA+++ +NS PKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP
Sbjct: 343 LTKPLISCLLPPNQASSSVSNSRPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIERP 402

Query: 121 VYTIHFFWRKFDDTYMRPIFGGPRNNQ-PGGSRC 154
           VYTIH+FWRKFDD+YMRPIFGGPR+NQ PGGS C
Sbjct: 403 VYTIHYFWRKFDDSYMRPIFGGPRHNQPPGGSGC 436

[Close]
BLAST of Lag0038097 vs. ExPASy Swiss-Prot
Match: Q8S397 (Sodium/hydrogen exchanger 4 OS=Arabidopsis thaliana OX=3702 GN=NHX4 PE=2 SV=2)

HSP 1 Score: 213.0 bits (541), Expect = 2.4e-54
Identity = 109/151 (72.19%), Postives = 125/151 (82.78%), Query Frame = 0 

Query: 2   ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFL 61
           ITFK Q+IIWWAGLMRGAVSIALAFKQFTYSGVTLDP NA M+T TT+VVLFTT+VFGFL
Sbjct: 377 ITFKHQVIIWWAGLMRGAVSIALAFKQFTYSGVTLDPVNAAMVTNTTIVVLFTTLVFGFL 436

Query: 62  TKPLIRCLLPPNQATNNAN---NSTPKFTEEDITLPLLSMEESAATNVLRAKDSLSMLIE 121
           TKPL+  LLP + + N  N    + P   +ED TLPLLS +ESA+TN  RAKDS+S+L+E
Sbjct: 437 TKPLVNYLLPQDASHNTGNRGKRTEPGSPKEDATLPLLSFDESASTNFNRAKDSISLLME 496

Query: 122 RPVYTIHFFWRKFDDTYMRPIFGGP-RNNQP 149
           +PVYTIH +WRKFDDTYMRPIFGGP R NQP
Sbjct: 497 QPVYTIHRYWRKFDDTYMRPIFGGPRRENQP 527

[Close]
BLAST of Lag0038097 vs. ExPASy Swiss-Prot
Match: Q68KI4 (Sodium/hydrogen exchanger 1 OS=Arabidopsis thaliana OX=3702 GN=NHX1 PE=1 SV=2)

HSP 1 Score: 129.8 bits (325), Expect = 2.6e-29
Identity = 75/147 (51.02%), Postives = 99/147 (67.35%), Query Frame = 0 

Query: 2   ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFL 61
           I F  Q++IWW+GLMRGAVS+ALA+ +FT +G T    NA MIT T  V LF+TVVFG L
Sbjct: 375 INFNMQVVIWWSGLMRGAVSMALAYNKFTRAGHTDVRGNAIMITSTITVCLFSTVVFGML 434

Query: 62  TKPLIRCLLPPNQATNN--ANNSTPKFTEEDITLPLLS----MEESAATNVLRAKDSLSM 121
           TKPLI  LLP   AT +  ++++TPK     I +PLL     +E S   NV R  DS+  
Sbjct: 435 TKPLISYLLPHQNATTSMLSDDNTPK----SIHIPLLDQDSFIEPSGNHNVPR-PDSIRG 494

Query: 122 LIERPVYTIHFFWRKFDDTYMRPIFGG 143
            + RP  T+H++WR+FDD++MRP+FGG
Sbjct: 495 FLTRPTRTVHYYWRQFDDSFMRPVFGG 516

[Close]
BLAST of Lag0038097 vs. ExPASy Swiss-Prot
Match: Q56XP4 (Sodium/hydrogen exchanger 2 OS=Arabidopsis thaliana OX=3702 GN=NHX2 PE=2 SV=2)

HSP 1 Score: 129.8 bits (325), Expect = 2.6e-29
Identity = 75/152 (49.34%), Postives = 100/152 (65.79%), Query Frame = 0 

Query: 2   ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFL 61
           I+ KQQ++IWWAGLMRGAVS+ALA+ +FT SG T    NA MIT T  V LF+T+VFG L
Sbjct: 377 ISIKQQVVIWWAGLMRGAVSMALAYNKFTRSGHTELRGNAIMITSTITVCLFSTMVFGML 436

Query: 62  TKPLIRCLLPPNQATNN-----ANNSTPKFTEEDITLPLL------SMEESAATNVLRAK 121
           TKPLIR L+P  +AT +     +++STPK     I +PLL      S E   +   +   
Sbjct: 437 TKPLIRYLMPHQKATTSTTSMLSDDSTPK----SIHIPLLDGEQLDSFELPGSHQDVPRP 496

Query: 122 DSLSMLIERPVYTIHFFWRKFDDTYMRPIFGG 143
           +SL   + RP  T+H++WR+FDD +MRP+FGG
Sbjct: 497 NSLRGFLMRPTRTVHYYWRQFDDAFMRPVFGG 524

[Close]
BLAST of Lag0038097 vs. ExPASy Swiss-Prot
Match: Q84WG1 (Sodium/hydrogen exchanger 3 OS=Arabidopsis thaliana OX=3702 GN=NHX3 PE=1 SV=2)

HSP 1 Score: 85.1 bits (209), Expect = 7.4e-16
Identity = 55/101 (54.46%), Postives = 68/101 (67.33%), Query Frame = 0 

Query: 2   ITFKQQIIIWWAGLMRGAVSIALAFKQFTYSGVTLDPTNATMITITTVVVLFTTVVFGFL 61
           I  K+Q+ IWWAGLMRGAVS+ALA+ QFT SG T    NA MIT T  VVLF+TVVFG L
Sbjct: 378 IDLKKQVTIWWAGLMRGAVSMALAYNQFTTSGHTKVLGNAIMITSTITVVLFSTVVFGLL 437

Query: 62  TKPLIRCLLPPN-QATNNANNSTPKFTEEDITL--PLLSME 100
           TKPL++ L P + Q++  A   T + +  D  L  PLLS +
Sbjct: 438 TKPLVKHLQPSSKQSSTTALQITLRSSFHDPILHEPLLSTQ 478

The following BLAST results are available for this feature:
BLAST of Lag0038097 vs. NCBI nr
Match NameE-valueIdentityDescription
XP_022940663.15.1e-7091.56sodium/hydrogen exchanger 4 [Cucurbita moschata][more]
XP_023522086.11.9e-6990.91sodium/hydrogen exchanger 4 [Cucurbita pepo subsp. pepo][more]
XP_038897275.15.6e-6987.66sodium/hydrogen exchanger 4 [Benincasa hispida][more]
XP_022139522.17.3e-6987.97sodium/hydrogen exchanger 4 [Momordica charantia][more]
TYK08093.17.3e-6988.31sodium/hydrogen exchanger 4 [Cucumis melo var. makuwa][more]
BLAST of Lag0038097 vs. ExPASy Swiss-Prot
Match NameE-valueIdentityDescription
Q8S3972.4e-5472.19Sodium/hydrogen exchanger 4 OS=Arabidopsis thaliana OX=3702 GN=NHX4 PE=2 SV=2[more]
Q68KI42.6e-2951.02Sodium/hydrogen exchanger 1 OS=Arabidopsis thaliana OX=3702 GN=NHX1 PE=1 SV=2[more]
Q56XP42.6e-2949.34Sodium/hydrogen exchanger 2 OS=Arabidopsis thaliana OX=3702 GN=NHX2 PE=2 SV=2[more]
Q84WG17.4e-1654.46Sodium/hydrogen exchanger 3 OS=Arabidopsis thaliana OX=3702 GN=NHX3 PE=1 SV=2[more]
InterPro
Analysis Name: InterPro Annotations of Sponge gourd (AG-4) v1
Date Performed: 2022-08-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006153Cation/H+ exchangerPFAMPF00999Na_H_Exchangercoord: 2..67
e-value: 1.0E-7
score: 31.1
NoneNo IPR availablePANTHERPTHR10110:SF180SODIUM/HYDROGEN EXCHANGERcoord: 2..147
IPR018422Cation/H+ exchanger, CPA1 familyPANTHERPTHR10110SODIUM/HYDROGEN EXCHANGERcoord: 2..147

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Lag0038097.1Lag0038097.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0098656 anion transmembrane transport
biological_process GO:0071805 potassium ion transmembrane transport
biological_process GO:1902600 proton transmembrane transport
biological_process GO:0051453 regulation of intracellular pH
biological_process GO:0098719 sodium ion import across plasma membrane
biological_process GO:0006812 cation transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0005886 plasma membrane
molecular_function GO:0015386 potassium:proton antiporter activity
molecular_function GO:0015385 sodium:proton antiporter activity
molecular_function GO:0015299 solute:proton antiporter activity