Lag0019921 (gene) Sponge gourd (AG‐4) v1

Overview
NameLag0019921
Typegene
OrganismLuffa acutangula (Sponge gourd (AG‐4) v1)
DescriptionMevalonate kinase
Locationchr5: 46727834 .. 46730498 (+)
RNA-Seq ExpressionLag0019921
SyntenyLag0019921
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGAAGTTAAGGCCAGAGCTCCTGGAAAAATCATACTCTCCGGTGAACATGCAGTCGTACATGGATCGACGGCTGTCGCTGCCTCCATCAGTCTCTATACTTCCGTTTCCCTTGCATTCCCCAGTCAGTCCGGTAAACTCTCGCTCTCTCTCTCTCCTGAGGCTTTTAACTTTGTGGAAGTGTAGGATCTGAAGGGGATGAATTTCCAGGGATTGAGTTCCTTGGACGTGATGATCCAATTGATCGACATCCTTTAAATGCTTTCACGAAAACTCTTTTGATTTTACACAATCTTTCTCTCGATGTTTACTATTTTGTTTATTGATTCTCTGGTGTTCTGTGTGCGTATTTTATGAACGGAAGCCGACTAAGCAAAGATATGTTGTGACTGTGAGAATCAAAGATGAGAAATGTTGATATGTAGACTTGTAGAGAGTATATGACATGGAATTGTCGATTAGATGCCGGTTGGACAGAAAATTTTGAGAACATTTGCTGGAATACAAATTTAGGATATACGTAGATCATTTTTTGGGAGTATGTGATCACAAGTGTTTGACAAGATTTTGACGGAACAATCATAATTTACTCTTCAGTAACTAGTTTTAAATTCTACATTATGATAATCTCGATAGTTTAATCTATCGATGATTTACTGTCAGTCTTGAAATTGCAGACATTACCAAAGAAAATCAAGGAGATTATTGATATGTTAACGAGATAAGAAACGCTGAGAAAACGTCCGCACCTTCTTTTTCCTCTGCAGTTTTCTGGTCATTACGTGTTATGAATGGTATCTTGATATAGACCGTTGTCTAATGTCTTGTTACTTCGTCAATCAAAATAATTCACTTTAAATTTCTGGGTTAATTTTATTTCTCACGAGATCAAATGCATTTGTTATTAGACAACGATGACACCCTCAAACTCCAGCTGAAGGATATGGCACTGGAGTTTTCGTGGCCAGTTGGTAGAATTAAAGAAGCTCTGGCCGAATTTAGTACCGCCATTTCCTCATCATCACCAACAGCATGCCCAGCCGAGTGCTTGAGATCAATTGGTTCTCTAGTTGAAGAACAAAATATTCCTGAAGCAAAGATTGGTCTTGCATCTGGGGTGTCAGCATTCCTCTGGCTATACTCCTGCATCCAAGGGTATGTATGGTACAATTGACTTGTGTTGTGTGAAATTTTTGTTTCTGTTTCTCCCTGTGTTTTTAAGCCATTTTTCATTCTGTGTTTCAGATTTAAGCCTGCTACAGTGGTTGTCACATCTGAGCTTCCTCTTGGATCTGGCCTGGGATCATCTGCTGCTTTTTGTGTTGCGCTTTCAGCTGCTCTACTTGCTTTATCTGATTCTGTAAGCGTGGACATGGCGCACCAAGGATGGTCAAGTTTTGGGGAAAAAGAACTTGATTTGTTGAACACATGGGCCTTTCAAGGTGAAAAGATAATTCATGGAAAGCCATCTGGAATCGACAACACAGTAAGCACATATGGTATGTCATCAATTTACCAATTGGATACTTTTACAATTTTATTATTATTTACCATGAAATGAAATTAGAACATCAGACTGAATCAATCTGGATCTACCAAATATCATTACGATGTCAAGGCCTAAAAATCGTATGGTGGTAACTCTAGACTGATCTAAATAACTAGCTCAAGAGAGAAATGTGTTCTGAAAATTTCCTTTCCGTGGTTAGTGGGAATGTTCCATCGTTTCCATGATTTCATCCCAATGATCAAGAAGAAACAATATGAAAGCATAGACATTTAAAGATGTACGAGCAATTTGTTCAGGCAACAAAAATGGAATTGAATGGAAAACACTGTTGTCATCAATTCATATGTTATACAACATATATGTTTGTTACTATTCCAGCATGCAAGAGGATTTTTATCTCTTCCTAAATAGAGAATCTTGTGTCAGGCAATATGATCAAATTCAAGTCGGGTAGCTTAACCCCCATCAAGTCCGACCTACCATTGAAAATGCTTATAACCTACACAAAAGTCGGGAGAAACACGAAGGCTTTAGTTGCTGGTGTTTCAGAAAGGACGATCAGACATCATGATGCATTGAACTTCATATTTAATGCTGTTGATTCCATTAGCAAGGAGTTATCAACCATTATTGAATCCCCTGTATCCATAACTGAGAAGGAAGAGAACATAGCAGAGCTGATGGAAATGAATCAAGGATTGCTCCAGAGCATGGGGGTAAGCCATGCTTCAATAGAAACTGTTCTAAGGACTACATTGAAGTACAAGTTAGCATCCAAATTGACAGGAGCTGGAGGTGGTGGCTGTGTTCTGACGCTCTTGCCAACTTGTATGTTCTCTTAGTCTGTCTACTCTTTTACACATTTTGCATTAAAGGCTAGTTTAGGAATGATTTTAGAATGACTGGAAATCACTCCTTAGAGCAAGAGTGATTTGGAAGGCCATTCTAAAATCACTCGAACATATCTCTTGAGTCGCATTTCTCGAGTCTATTTTCATGTACATTCATAGATTTCCTTAACTATATTGAAAAACAGTGCTTTCAGGAACAATCGTAGATATGGTAATTTCAGAGCTAGAGTCGTGCGGCTTCCAGTGTCTAATTGCGGAAATTGGAGGAAGCGGAGTGGAGATATCTTTTGATGCTTCATCATGA

mRNA sequence

ATGGAAGTTAAGGCCAGAGCTCCTGGAAAAATCATACTCTCCGGTGAACATGCAGTCGTACATGGATCGACGGCTGTCGCTGCCTCCATCAGTCTCTATACTTCCGTTTCCCTTGCATTCCCCAGTCAGTCCGACAACGATGACACCCTCAAACTCCAGCTGAAGGATATGGCACTGGAGTTTTCGTGGCCAGTTGGTAGAATTAAAGAAGCTCTGGCCGAATTTAGTACCGCCATTTCCTCATCATCACCAACAGCATGCCCAGCCGAGTGCTTGAGATCAATTGGTTCTCTAGTTGAAGAACAAAATATTCCTGAAGCAAAGATTGGTCTTGCATCTGGGGTGTCAGCATTCCTCTGGCTATACTCCTGCATCCAAGGATTTAAGCCTGCTACAGTGGTTGTCACATCTGAGCTTCCTCTTGGATCTGGCCTGGGATCATCTGCTGCTTTTTGTGTTGCGCTTTCAGCTGCTCTACTTGCTTTATCTGATTCTGTAAGCGTGGACATGGCGCACCAAGGATGGTCAAGTTTTGGGGAAAAAGAACTTGATTTGTTGAACACATGGGCCTTTCAAGGTGAAAAGATAATTCATGGAAAGCCATCTGGAATCGACAACACAGTAAGCACATATGGCAATATGATCAAATTCAAGTCGGGTAGCTTAACCCCCATCAAGTCCGACCTACCATTGAAAATGCTTATAACCTACACAAAAGTCGGGAGAAACACGAAGGCTTTAGTTGCTGGTGTTTCAGAAAGGACGATCAGACATCATGATGCATTGAACTTCATATTTAATGCTGTTGATTCCATTAGCAAGGAGTTATCAACCATTATTGAATCCCCTGTATCCATAACTGAGAAGGAAGAGAACATAGCAGAGCTGATGGAAATGAATCAAGGATTGCTCCAGAGCATGGGGGTAAGCCATGCTTCAATAGAAACTGTTCTAAGGACTACATTGAAGTACAAGTTAGCATCCAAATTGACAGGAGCTGGAGGTGGTGGCTGTGTTCTGACGCTCTTGCCAACTTTGCTTTCAGGAACAATCGTAGATATGGTAATTTCAGAGCTAGAGTCGTGCGGCTTCCAGTGTCTAATTGCGGAAATTGGAGGAAGCGGAGTGGAGATATCTTTTGATGCTTCATCATGA

Coding sequence (CDS)

ATGGAAGTTAAGGCCAGAGCTCCTGGAAAAATCATACTCTCCGGTGAACATGCAGTCGTACATGGATCGACGGCTGTCGCTGCCTCCATCAGTCTCTATACTTCCGTTTCCCTTGCATTCCCCAGTCAGTCCGACAACGATGACACCCTCAAACTCCAGCTGAAGGATATGGCACTGGAGTTTTCGTGGCCAGTTGGTAGAATTAAAGAAGCTCTGGCCGAATTTAGTACCGCCATTTCCTCATCATCACCAACAGCATGCCCAGCCGAGTGCTTGAGATCAATTGGTTCTCTAGTTGAAGAACAAAATATTCCTGAAGCAAAGATTGGTCTTGCATCTGGGGTGTCAGCATTCCTCTGGCTATACTCCTGCATCCAAGGATTTAAGCCTGCTACAGTGGTTGTCACATCTGAGCTTCCTCTTGGATCTGGCCTGGGATCATCTGCTGCTTTTTGTGTTGCGCTTTCAGCTGCTCTACTTGCTTTATCTGATTCTGTAAGCGTGGACATGGCGCACCAAGGATGGTCAAGTTTTGGGGAAAAAGAACTTGATTTGTTGAACACATGGGCCTTTCAAGGTGAAAAGATAATTCATGGAAAGCCATCTGGAATCGACAACACAGTAAGCACATATGGCAATATGATCAAATTCAAGTCGGGTAGCTTAACCCCCATCAAGTCCGACCTACCATTGAAAATGCTTATAACCTACACAAAAGTCGGGAGAAACACGAAGGCTTTAGTTGCTGGTGTTTCAGAAAGGACGATCAGACATCATGATGCATTGAACTTCATATTTAATGCTGTTGATTCCATTAGCAAGGAGTTATCAACCATTATTGAATCCCCTGTATCCATAACTGAGAAGGAAGAGAACATAGCAGAGCTGATGGAAATGAATCAAGGATTGCTCCAGAGCATGGGGGTAAGCCATGCTTCAATAGAAACTGTTCTAAGGACTACATTGAAGTACAAGTTAGCATCCAAATTGACAGGAGCTGGAGGTGGTGGCTGTGTTCTGACGCTCTTGCCAACTTTGCTTTCAGGAACAATCGTAGATATGGTAATTTCAGAGCTAGAGTCGTGCGGCTTCCAGTGTCTAATTGCGGAAATTGGAGGAAGCGGAGTGGAGATATCTTTTGATGCTTCATCATGA

Protein sequence

MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALEFSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLWLYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGEKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKVGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPVSITEKEENIAELMEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVISELESCGFQCLIAEIGGSGVEISFDASS
Homology
BLAST of Lag0019921 vs. NCBI nr
Match: XP_023517970.1 (mevalonate kinase-like isoform X1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 673.3 bits (1736), Expect = 1.2e-189
Identity = 357/388 (92.01%), Postives = 370/388 (95.36%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKIILSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQLKDMALE
Sbjct: 1   MEVRARAPGKIILSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+A F+TAISSSSPT+CPAECL+SIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAGFNTAISSSSPTSCPAECLKSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSC+QGFKPATVVVTSELPLGSGLGSSA+FCVALSAALLALSDSV VDMAHQGWSSFGE
Sbjct: 121 LYSCVQGFKPATVVVTSELPLGSGLGSSASFCVALSAALLALSDSVVVDMAHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+LPL+MLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLPLRMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVA VSERTIRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVASVSERTIRHHDALNFIFNAVDSISKELSAIIESPVCGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT LSGTIVDMVI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPTSLSGTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           SELESCGFQCLIA+IGGSGVEISFDASS
Sbjct: 361 SELESCGFQCLIADIGGSGVEISFDASS 388

BLAST of Lag0019921 vs. NCBI nr
Match: KAG6600163.1 (Mevalonate kinase, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 671.8 bits (1732), Expect = 3.6e-189
Identity = 358/387 (92.51%), Postives = 368/387 (95.09%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKIILSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQLKDMALE
Sbjct: 18  MEVRARAPGKIILSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLKDMALE 77

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+A F+TAISSSSPT+CPAECL+SIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 78  FSWPVGRIKEAVAGFNTAISSSSPTSCPAECLKSIGALVEEQNIPEAKIGLASGVSAFLW 137

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSV VDM HQGWSSFGE
Sbjct: 138 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDMVHQGWSSFGE 197

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+LPL+MLIT TK 
Sbjct: 198 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLPLRMLITNTKE 257

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVA VSERTIRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 258 GRNTKALVASVSERTIRHHDALNFIFNAVDSISKELSGIIESPVSGELSISEKEENIAEL 317

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI
Sbjct: 318 MEMNQGLLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 377

Query: 361 SELESCGFQCLIAEIGGSGVEISFDAS 384
           SELESCGFQCLIA IGGSGVEISFDAS
Sbjct: 378 SELESCGFQCLIAGIGGSGVEISFDAS 404

BLAST of Lag0019921 vs. NCBI nr
Match: XP_022941719.1 (mevalonate kinase-like isoform X1 [Cucurbita moschata])

HSP 1 Score: 667.9 bits (1722), Expect = 5.1e-188
Identity = 356/387 (91.99%), Postives = 366/387 (94.57%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKIILSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQLKDMALE
Sbjct: 1   MEVRARAPGKIILSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+A F+TAISSSSPT+CPAECL+SIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAGFNTAISSSSPTSCPAECLKSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSV VDM HQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDMVHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+LPL+MLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLPLRMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVA VSERTIRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVASVSERTIRHHDALNFIFNAVDSISKELSGIIESPVSGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT LSGTIVDMVI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPTSLSGTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDAS 384
           SELESCGFQCLIA IGG GVEISFDAS
Sbjct: 361 SELESCGFQCLIAGIGGGGVEISFDAS 387

BLAST of Lag0019921 vs. NCBI nr
Match: AEM42972.1 (mevalonate kinase [Siraitia grosvenorii])

HSP 1 Score: 667.9 bits (1722), Expect = 5.1e-188
Identity = 356/388 (91.75%), Postives = 369/388 (95.10%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEVKARAPGKIILSGEHAVVHGSTAVAASISL+TSV LAFPS S NDDTLKL+LKDMALE
Sbjct: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLHTSVFLAFPSHSGNDDTLKLELKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEALAEFS+AI SSSPT+CPAECLRSIG+LVEEQNIPEA+ GLASG+SAFLW
Sbjct: 61  FSWPVGRIKEALAEFSSAI-SSSPTSCPAECLRSIGALVEEQNIPEARTGLASGMSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDM HQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMVHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAF+GEKIIHG PSGIDNTVSTYGNMIKFKSGSLT IKS+LPLKMLIT TKV
Sbjct: 181 KELDLLNKWAFEGEKIIHGNPSGIDNTVSTYGNMIKFKSGSLTLIKSNLPLKMLITNTKV 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVAGVSERTIRH DALNF+FNAVDSISKELS IIESPV    SITEKEENIAEL
Sbjct: 241 GRNTKALVAGVSERTIRHPDALNFVFNAVDSISKELSAIIESPVSGELSITEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVD VI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDKVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           +ELESCGFQCLIAEIGG GVEISF+ +S
Sbjct: 361 AELESCGFQCLIAEIGGRGVEISFNGAS 387

BLAST of Lag0019921 vs. NCBI nr
Match: XP_022990450.1 (LOW QUALITY PROTEIN: mevalonate kinase-like [Cucurbita maxima])

HSP 1 Score: 657.5 bits (1695), Expect = 7.0e-185
Identity = 352/388 (90.72%), Postives = 364/388 (93.81%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKI+LSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQL DMALE
Sbjct: 1   MEVRARAPGKIMLSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLNDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+AEF+TAISSSSPT+CPAECLRSIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAEFNTAISSSSPTSCPAECLRSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATV+VTSELPLGSGLGSSAAFCVALSAALLALSDSV VD AHQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVIVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDRAHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+L LKMLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLALKMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVAG SER IRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVAGXSERMIRHHDALNFIFNAVDSISKELSAIIESPVSGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQG+LQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT    TIVDMVI
Sbjct: 301 MEMNQGVLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPT---XTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           SELESCGFQCLIA+IGGSGVEISFDASS
Sbjct: 361 SELESCGFQCLIADIGGSGVEISFDASS 385

BLAST of Lag0019921 vs. ExPASy Swiss-Prot
Match: P46086 (Mevalonate kinase OS=Arabidopsis thaliana OX=3702 GN=At5g27450 PE=2 SV=1)

HSP 1 Score: 481.5 bits (1238), Expect = 9.0e-135
Identity = 258/383 (67.36%), Postives = 307/383 (80.16%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQS-DNDDTLKLQLKDMAL 60
           MEVKARAPGKIIL+GEHAVVHGSTAVAA+I LYT V+L FP  S +N+D L LQLKD++L
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  EFSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFL 120
           EFSW + RIKEA+   S+ +  S+P +C  E L+SI  LVEEQN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFG 180
           WLY+ I GF PATVV+ SELP GSGLGSSAA CVAL+AALLA   S+S      GWSS  
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTK 240
           E  L+LLN WAF+GEKIIHGKPSGIDNTVS YGNMIKF SG +T ++S++PL+MLIT T+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIES--PVSITEKEENIAELM 300
           VGRNTKALV+GVS+R +RH DA+  +FNAVDSISKEL+ II+S    S+TEKEE I ELM
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELM 300

Query: 301 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 360
           EMNQGLL SMGVSH+SIE V+ TT+K+KL SKLTGAGGGGCVLTLLPT   GT+VD V+ 
Sbjct: 301 EMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPT---GTVVDKVVE 360

Query: 361 ELESCGFQCLIAEIGGSGVEISF 381
           ELES GFQC  A IGG+G +I +
Sbjct: 361 ELESSGFQCFTALIGGNGAQICY 378

BLAST of Lag0019921 vs. ExPASy Swiss-Prot
Match: Q03426 (Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1)

HSP 1 Score: 233.8 bits (595), Expect = 3.3e-60
Identity = 147/381 (38.58%), Postives = 224/381 (58.79%), Query Frame = 0

Query: 7   APGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALEFSWPVG 66
           APGK+IL GEHAVVHG  A+A S++L T + L    Q  ++  + L L ++ ++ +W V 
Sbjct: 10  APGKVILHGEHAVVHGKVALAVSLNLRTFLRL----QPHSNGKVDLSLPNIGIKRAWDVA 69

Query: 67  RIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLWLYSCI- 126
           R++     F      ++PT+   E L+ +  L ++  + E        V AFL+LY  I 
Sbjct: 70  RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTE-----RLAVLAFLYLYLSIC 129

Query: 127 ---QGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGW-SSFGEK 186
              +      +VV SELP G+GLGSSAA+ V L+AALL + + +   +      + + ++
Sbjct: 130 RKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKE 189

Query: 187 ELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKVG 246
           +L+L+N WAFQGE++IHG PSG+DN VST+G  +++  G ++ +K    L++L+T TKV 
Sbjct: 190 DLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVP 249

Query: 247 RNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTII----ESPVSITEKEENIAELM 306
           RNT+ALVAGV  R ++  + +  +  ++D+IS E   ++    E+P    E+   + EL+
Sbjct: 250 RNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPA--PEQYLVLEELI 309

Query: 307 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 366
           +MNQ  L ++GV HAS++ + + T    L SKLTGAGGGGC +TLL   L    V+    
Sbjct: 310 DMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQ 369

Query: 367 ELESCGFQCLIAEIGGSGVEI 379
            L SCGF CL   IG  GV I
Sbjct: 370 ALTSCGFDCLETSIGAPGVSI 379

BLAST of Lag0019921 vs. ExPASy Swiss-Prot
Match: Q9R008 (Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1)

HSP 1 Score: 226.5 bits (576), Expect = 5.2e-58
Identity = 147/377 (38.99%), Postives = 221/377 (58.62%), Query Frame = 0

Query: 7   APGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALEFSWPVG 66
           APGK+IL GEHAVVHG  A+AA+++L T + L    +  ++  + + L ++ ++  W VG
Sbjct: 10  APGKVILHGEHAVVHGKVALAAALNLRTFLLL----RPQSNGKVSVNLPNIGIKQVWDVG 69

Query: 67  RIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLWLYSCI- 126
            ++     F      S PT    E L+ +G L  ++   E   G+A  + AFL+LY  I 
Sbjct: 70  MLQRLDTSFLEQGDVSVPTLEQLEKLKKMGDLPRDRAGNE---GMA--LLAFLYLYLAIC 129

Query: 127 ---QGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAH-QGWSSFGEK 186
              +      +VV SELP G+GLGSSAA+ V L+AALL   + VS  +      S + E+
Sbjct: 130 RKQRTLPSLDMVVWSELPPGAGLGSSAAYSVCLAAALLTACEEVSNPLKDGVSVSRWPEE 189

Query: 187 ELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKVG 246
           +L  +N WAF+GE++IHG PSG+DN VST+G  ++F+ G+++ +KS   L++L+T TKV 
Sbjct: 190 DLKSINKWAFEGERVIHGNPSGVDNAVSTWGGALRFQQGTMSSLKSLPSLQILLTNTKVP 249

Query: 247 RNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPVSITEKEENIA--ELMEM 306
           R+TKALVA V  R  +  + +  +  ++D+IS E   ++   V+    E+ +   EL++M
Sbjct: 250 RSTKALVAAVRSRLTKFPEIVAPLLTSIDAISLECERVLGEMVAAPVPEQYLVLEELIDM 309

Query: 307 NQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVISEL 366
           NQ  L ++GV H S++ + + T  + L SKLTGAGGGGC +TLL   L    V+     L
Sbjct: 310 NQHHLNALGVGHNSLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLEQATVEAAKQAL 369

Query: 367 ESCGFQCLIAEIGGSGV 377
            SCGF C    IG  GV
Sbjct: 370 TSCGFDCWETSIGAPGV 377

BLAST of Lag0019921 vs. ExPASy Swiss-Prot
Match: Q5E9T8 (Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1)

HSP 1 Score: 219.5 bits (558), Expect = 6.3e-56
Identity = 139/384 (36.20%), Postives = 214/384 (55.73%), Query Frame = 0

Query: 7   APGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALEFSWPVG 66
           APGK+IL GEHAVVHG  A+A +++L T + L    Q  ++  + L L ++ +  +W V 
Sbjct: 10  APGKVILHGEHAVVHGKVALAVALNLRTFLRL----QPHSNGRVGLNLPNIGVRRAWDVA 69

Query: 67  RIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLWLYSCI- 126
            ++     F     S++ TA   E L+ +    ++   PE        V AFL+LY  I 
Sbjct: 70  SLQLLDTSFLGHGDSAALTAKHVEKLKEVAGFPKDCVDPE-----HLAVLAFLYLYLSIC 129

Query: 127 ---QGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAH-QGWSSFGEK 186
              +      + V SELP G+GLGSSAA+ V L+AALL   + +   +   +    + E+
Sbjct: 130 QSQRALPSLDITVWSELPTGAGLGSSAAYSVCLAAALLTACEEIPNPLKDGEAAGRWTEE 189

Query: 187 ELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKVG 246
            L+L+N WAFQGE++IHG PSG+DN VST+G  ++++ G ++ +K    LK+L+  TKV 
Sbjct: 190 NLELINKWAFQGERVIHGNPSGVDNAVSTWGGALRYQQGKISSLKRPPVLKILLINTKVP 249

Query: 247 RNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPVSITEKEE--NIAELMEM 306
           R+TK LVA V  R ++  + +  +  ++D+IS E   ++    +    E    + EL++M
Sbjct: 250 RSTKVLVANVRSRLLKFPEIVAPLLTSIDAISLECERVLGEMAAAPTPEHYLTLEELIDM 309

Query: 307 NQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVISEL 366
           NQ  L ++GV HAS++ + + T  + L SKLTGAGGGGC +TLL   +    V+     L
Sbjct: 310 NQHHLNALGVGHASLDQLCQVTTAHGLHSKLTGAGGGGCGITLLRPDVERPAVEATKRAL 369

Query: 367 ESCGFQCLIAEIGGSGVEISFDAS 384
             CGF C    +G  GV +   AS
Sbjct: 370 SGCGFDCWETSVGAPGVSVHTAAS 384

BLAST of Lag0019921 vs. ExPASy Swiss-Prot
Match: P17256 (Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 SV=1)

HSP 1 Score: 219.5 bits (558), Expect = 6.3e-56
Identity = 142/381 (37.27%), Postives = 220/381 (57.74%), Query Frame = 0

Query: 7   APGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALEFSWPVG 66
           APGK+IL GEHAVVHG  A+A +++L T + L    +  ++  + L L ++ ++  W V 
Sbjct: 10  APGKVILHGEHAVVHGKVALAVALNLRTFLVL----RPQSNGKVSLNLPNVGIKQVWDVA 69

Query: 67  RIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVS--AFLWLYSC 126
            ++     F       +PT    E L+ +  L      P   +G   G+S  AFL+LY  
Sbjct: 70  TLQLLDTGFLEQGDVPAPTLEQLEKLKKVAGL------PRDCVG-NEGLSLLAFLYLYLA 129

Query: 127 I----QGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQG-WSSFG 186
           I    +      ++V SELP G+GLGSSAA+ V ++AALL   + V+  +  +G   S+ 
Sbjct: 130 ICRKQRTLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWP 189

Query: 187 EKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTK 246
           E++L  +N WA++GE++IHG PSG+DN+VST+G  ++++ G ++ +K    L++L+T TK
Sbjct: 190 EEDLKSINKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTK 249

Query: 247 VGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPVSITEKEENIA--ELM 306
           V R+TKALVAGV  R I+  + +  +  ++D+IS E   ++    +    E+ +   ELM
Sbjct: 250 VPRSTKALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMAAAPVPEQYLVLEELM 309

Query: 307 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 366
           +MNQ  L ++GV HAS++ + + T  + L SKLTGAGGGGC +TLL   L    V+    
Sbjct: 310 DMNQHHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQ 369

Query: 367 ELESCGFQCLIAEIGGSGVEI 379
            L  CGF C    IG  GV +
Sbjct: 370 ALTGCGFDCWETSIGAPGVSM 379

BLAST of Lag0019921 vs. ExPASy TrEMBL
Match: K7NBZ7 (Mevalonate kinase OS=Siraitia grosvenorii OX=190515 GN=MVK PE=2 SV=1)

HSP 1 Score: 667.9 bits (1722), Expect = 2.5e-188
Identity = 356/388 (91.75%), Postives = 369/388 (95.10%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEVKARAPGKIILSGEHAVVHGSTAVAASISL+TSV LAFPS S NDDTLKL+LKDMALE
Sbjct: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLHTSVFLAFPSHSGNDDTLKLELKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEALAEFS+AI SSSPT+CPAECLRSIG+LVEEQNIPEA+ GLASG+SAFLW
Sbjct: 61  FSWPVGRIKEALAEFSSAI-SSSPTSCPAECLRSIGALVEEQNIPEARTGLASGMSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDM HQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMVHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAF+GEKIIHG PSGIDNTVSTYGNMIKFKSGSLT IKS+LPLKMLIT TKV
Sbjct: 181 KELDLLNKWAFEGEKIIHGNPSGIDNTVSTYGNMIKFKSGSLTLIKSNLPLKMLITNTKV 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVAGVSERTIRH DALNF+FNAVDSISKELS IIESPV    SITEKEENIAEL
Sbjct: 241 GRNTKALVAGVSERTIRHPDALNFVFNAVDSISKELSAIIESPVSGELSITEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVD VI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDKVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           +ELESCGFQCLIAEIGG GVEISF+ +S
Sbjct: 361 AELESCGFQCLIAEIGGRGVEISFNGAS 387

BLAST of Lag0019921 vs. ExPASy TrEMBL
Match: A0A6J1FP94 (Mevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111447000 PE=3 SV=1)

HSP 1 Score: 667.9 bits (1722), Expect = 2.5e-188
Identity = 356/387 (91.99%), Postives = 366/387 (94.57%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKIILSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQLKDMALE
Sbjct: 1   MEVRARAPGKIILSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+A F+TAISSSSPT+CPAECL+SIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAGFNTAISSSSPTSCPAECLKSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSV VDM HQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDMVHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+LPL+MLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLPLRMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVA VSERTIRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVASVSERTIRHHDALNFIFNAVDSISKELSGIIESPVSGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT LSGTIVDMVI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPTSLSGTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDAS 384
           SELESCGFQCLIA IGG GVEISFDAS
Sbjct: 361 SELESCGFQCLIAGIGGGGVEISFDAS 387

BLAST of Lag0019921 vs. ExPASy TrEMBL
Match: A0A6J1JQ50 (Mevalonate kinase OS=Cucurbita maxima OX=3661 GN=LOC111487302 PE=3 SV=1)

HSP 1 Score: 657.5 bits (1695), Expect = 3.4e-185
Identity = 352/388 (90.72%), Postives = 364/388 (93.81%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKI+LSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQL DMALE
Sbjct: 1   MEVRARAPGKIMLSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLNDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+AEF+TAISSSSPT+CPAECLRSIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAEFNTAISSSSPTSCPAECLRSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATV+VTSELPLGSGLGSSAAFCVALSAALLALSDSV VD AHQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVIVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDRAHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+L LKMLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLALKMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVAG SER IRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVAGXSERMIRHHDALNFIFNAVDSISKELSAIIESPVSGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQG+LQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT    TIVDMVI
Sbjct: 301 MEMNQGVLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPT---XTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           SELESCGFQCLIA+IGGSGVEISFDASS
Sbjct: 361 SELESCGFQCLIADIGGSGVEISFDASS 385

BLAST of Lag0019921 vs. ExPASy TrEMBL
Match: A0A6J1CH50 (Mevalonate kinase OS=Momordica charantia OX=3673 GN=LOC111011387 PE=3 SV=1)

HSP 1 Score: 650.2 bits (1676), Expect = 5.4e-183
Identity = 345/388 (88.92%), Postives = 363/388 (93.56%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPS S NDDTLK+QLKDM+LE
Sbjct: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSHSGNDDTLKIQLKDMSLE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEALAEFS  I SSSPT+CPA CL+SIG+LVEEQNIPEAK GLASG+SAFLW
Sbjct: 61  FSWPVGRIKEALAEFSNVI-SSSPTSCPAACLKSIGALVEEQNIPEAKFGLASGLSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELP+GSGLGSSAAFCVA+SAALLALS+SVSVDMAHQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPIGSGLGSSAAFCVAVSAALLALSNSVSVDMAHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAF+GEKIIHGKPSGIDN VSTYGNMIKFKSGSL+ IK  LPL+MLIT TK 
Sbjct: 181 KELDLLNRWAFEGEKIIHGKPSGIDNAVSTYGNMIKFKSGSLSLIKPSLPLEMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESP----VSITEKEENIAEL 300
           GRNTKALVAGVSERTIRHHDALNF+FNAVD ISKELS IIESP    VSI+EKE+ +AEL
Sbjct: 241 GRNTKALVAGVSERTIRHHDALNFMFNAVDFISKELSAIIESPVSDEVSISEKEDCMAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVI 360
           MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLP+LLSGTIVDMVI
Sbjct: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPSLLSGTIVDMVI 360

Query: 361 SELESCGFQCLIAEIGGSGVEISFDASS 385
           +ELESCGFQCLIAEIGG GVEI FD  S
Sbjct: 361 AELESCGFQCLIAEIGGRGVEICFDEFS 387

BLAST of Lag0019921 vs. ExPASy TrEMBL
Match: A0A6J1FUJ0 (Mevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111447000 PE=3 SV=1)

HSP 1 Score: 603.2 bits (1554), Expect = 7.5e-169
Identity = 321/349 (91.98%), Postives = 331/349 (94.84%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQSDNDDTLKLQLKDMALE 60
           MEV+ARAPGKIILSGEHAVVHGS AVAASISLYTSVSLAF S SDNDDTLKLQLKDMALE
Sbjct: 1   MEVRARAPGKIILSGEHAVVHGSMAVAASISLYTSVSLAFHSHSDNDDTLKLQLKDMALE 60

Query: 61  FSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFLW 120
           FSWPVGRIKEA+A F+TAISSSSPT+CPAECL+SIG+LVEEQNIPEAKIGLASGVSAFLW
Sbjct: 61  FSWPVGRIKEAVAGFNTAISSSSPTSCPAECLKSIGALVEEQNIPEAKIGLASGVSAFLW 120

Query: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFGE 180
           LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSV VDM HQGWSSFGE
Sbjct: 121 LYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVVVDMVHQGWSSFGE 180

Query: 181 KELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTKV 240
           KELDLLN WAFQGEKIIHGKPSGIDNTVSTYGN IKFKSGSLT +KS+LPL+MLIT TK 
Sbjct: 181 KELDLLNKWAFQGEKIIHGKPSGIDNTVSTYGNTIKFKSGSLTLMKSNLPLRMLITNTKE 240

Query: 241 GRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIESPV----SITEKEENIAEL 300
           GRNTKALVA VSERTIRHHDALNFIFNAVDSISKELS IIESPV    SI+EKEENIAEL
Sbjct: 241 GRNTKALVASVSERTIRHHDALNFIFNAVDSISKELSGIIESPVSGELSISEKEENIAEL 300

Query: 301 MEMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPT 346
           MEMNQGLLQSMGVSHASIETV RTTLKYKLASKLTGAGGGGCVLTLLPT
Sbjct: 301 MEMNQGLLQSMGVSHASIETVQRTTLKYKLASKLTGAGGGGCVLTLLPT 349

BLAST of Lag0019921 vs. TAIR 10
Match: AT5G27450.1 (mevalonate kinase )

HSP 1 Score: 481.5 bits (1238), Expect = 6.4e-136
Identity = 258/383 (67.36%), Postives = 307/383 (80.16%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQS-DNDDTLKLQLKDMAL 60
           MEVKARAPGKIIL+GEHAVVHGSTAVAA+I LYT V+L FP  S +N+D L LQLKD++L
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  EFSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFL 120
           EFSW + RIKEA+   S+ +  S+P +C  E L+SI  LVEEQN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFG 180
           WLY+ I GF PATVV+ SELP GSGLGSSAA CVAL+AALLA   S+S      GWSS  
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTK 240
           E  L+LLN WAF+GEKIIHGKPSGIDNTVS YGNMIKF SG +T ++S++PL+MLIT T+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIES--PVSITEKEENIAELM 300
           VGRNTKALV+GVS+R +RH DA+  +FNAVDSISKEL+ II+S    S+TEKEE I ELM
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELM 300

Query: 301 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 360
           EMNQGLL SMGVSH+SIE V+ TT+K+KL SKLTGAGGGGCVLTLLPT   GT+VD V+ 
Sbjct: 301 EMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPT---GTVVDKVVE 360

Query: 361 ELESCGFQCLIAEIGGSGVEISF 381
           ELES GFQC  A IGG+G +I +
Sbjct: 361 ELESSGFQCFTALIGGNGAQICY 378

BLAST of Lag0019921 vs. TAIR 10
Match: AT5G27450.2 (mevalonate kinase )

HSP 1 Score: 481.5 bits (1238), Expect = 6.4e-136
Identity = 258/383 (67.36%), Postives = 307/383 (80.16%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQS-DNDDTLKLQLKDMAL 60
           MEVKARAPGKIIL+GEHAVVHGSTAVAA+I LYT V+L FP  S +N+D L LQLKD++L
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  EFSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFL 120
           EFSW + RIKEA+   S+ +  S+P +C  E L+SI  LVEEQN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFG 180
           WLY+ I GF PATVV+ SELP GSGLGSSAA CVAL+AALLA   S+S      GWSS  
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTK 240
           E  L+LLN WAF+GEKIIHGKPSGIDNTVS YGNMIKF SG +T ++S++PL+MLIT T+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIES--PVSITEKEENIAELM 300
           VGRNTKALV+GVS+R +RH DA+  +FNAVDSISKEL+ II+S    S+TEKEE I ELM
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELM 300

Query: 301 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 360
           EMNQGLL SMGVSH+SIE V+ TT+K+KL SKLTGAGGGGCVLTLLPT   GT+VD V+ 
Sbjct: 301 EMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPT---GTVVDKVVE 360

Query: 361 ELESCGFQCLIAEIGGSGVEISF 381
           ELES GFQC  A IGG+G +I +
Sbjct: 361 ELESSGFQCFTALIGGNGAQICY 378

BLAST of Lag0019921 vs. TAIR 10
Match: AT5G27450.3 (mevalonate kinase )

HSP 1 Score: 481.5 bits (1238), Expect = 6.4e-136
Identity = 258/383 (67.36%), Postives = 307/383 (80.16%), Query Frame = 0

Query: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASISLYTSVSLAFPSQS-DNDDTLKLQLKDMAL 60
           MEVKARAPGKIIL+GEHAVVHGSTAVAA+I LYT V+L FP  S +N+D L LQLKD++L
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  EFSWPVGRIKEALAEFSTAISSSSPTACPAECLRSIGSLVEEQNIPEAKIGLASGVSAFL 120
           EFSW + RIKEA+   S+ +  S+P +C  E L+SI  LVEEQN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSCIQGFKPATVVVTSELPLGSGLGSSAAFCVALSAALLALSDSVSVDMAHQGWSSFG 180
           WLY+ I GF PATVV+ SELP GSGLGSSAA CVAL+AALLA   S+S      GWSS  
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EKELDLLNTWAFQGEKIIHGKPSGIDNTVSTYGNMIKFKSGSLTPIKSDLPLKMLITYTK 240
           E  L+LLN WAF+GEKIIHGKPSGIDNTVS YGNMIKF SG +T ++S++PL+MLIT T+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERTIRHHDALNFIFNAVDSISKELSTIIES--PVSITEKEENIAELM 300
           VGRNTKALV+GVS+R +RH DA+  +FNAVDSISKEL+ II+S    S+TEKEE I ELM
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQSKDETSVTEKEERIKELM 300

Query: 301 EMNQGLLQSMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDMVIS 360
           EMNQGLL SMGVSH+SIE V+ TT+K+KL SKLTGAGGGGCVLTLLPT   GT+VD V+ 
Sbjct: 301 EMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLPT---GTVVDKVVE 360

Query: 361 ELESCGFQCLIAEIGGSGVEISF 381
           ELES GFQC  A IGG+G +I +
Sbjct: 361 ELESSGFQCFTALIGGNGAQICY 378

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_023517970.11.2e-18992.01mevalonate kinase-like isoform X1 [Cucurbita pepo subsp. pepo][more]
KAG6600163.13.6e-18992.51Mevalonate kinase, partial [Cucurbita argyrosperma subsp. sororia][more]
XP_022941719.15.1e-18891.99mevalonate kinase-like isoform X1 [Cucurbita moschata][more]
AEM42972.15.1e-18891.75mevalonate kinase [Siraitia grosvenorii][more]
XP_022990450.17.0e-18590.72LOW QUALITY PROTEIN: mevalonate kinase-like [Cucurbita maxima][more]
Match NameE-valueIdentityDescription
P460869.0e-13567.36Mevalonate kinase OS=Arabidopsis thaliana OX=3702 GN=At5g27450 PE=2 SV=1[more]
Q034263.3e-6038.58Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1[more]
Q9R0085.2e-5838.99Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1[more]
Q5E9T86.3e-5636.20Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1[more]
P172566.3e-5637.27Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 SV=1[more]
Match NameE-valueIdentityDescription
K7NBZ72.5e-18891.75Mevalonate kinase OS=Siraitia grosvenorii OX=190515 GN=MVK PE=2 SV=1[more]
A0A6J1FP942.5e-18891.99Mevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111447000 PE=3 SV=1[more]
A0A6J1JQ503.4e-18590.72Mevalonate kinase OS=Cucurbita maxima OX=3661 GN=LOC111487302 PE=3 SV=1[more]
A0A6J1CH505.4e-18388.92Mevalonate kinase OS=Momordica charantia OX=3673 GN=LOC111011387 PE=3 SV=1[more]
A0A6J1FUJ07.5e-16991.98Mevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111447000 PE=3 SV=1[more]
Match NameE-valueIdentityDescription
AT5G27450.16.4e-13667.36mevalonate kinase [more]
AT5G27450.26.4e-13667.36mevalonate kinase [more]
AT5G27450.36.4e-13667.36mevalonate kinase [more]
InterPro
Analysis Name: InterPro Annotations of Sponge gourd (AG-4) v1
Date Performed: 2022-08-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 286..306
NoneNo IPR availablePRINTSPR00959MEVGALKINASEcoord: 137..159
score: 50.13
coord: 327..344
score: 52.12
coord: 194..213
score: 30.0
coord: 7..31
score: 39.53
NoneNo IPR availablePANTHERPTHR43290:SF3MEVALONATE KINASEcoord: 1..380
IPR014721Ribosomal protein S5 domain 2-type fold, subgroupGENE3D3.30.230.10coord: 6..376
e-value: 2.0E-112
score: 377.8
IPR013750GHMP kinase, C-terminal domainPFAMPF08544GHMP_kinases_Ccoord: 291..345
e-value: 4.1E-6
score: 27.1
IPR006204GHMP kinase N-terminal domainPFAMPF00288GHMP_kinases_Ncoord: 133..213
e-value: 4.5E-19
score: 68.4
IPR036554GHMP kinase, C-terminal domain superfamilyGENE3D3.30.70.890coord: 228..373
e-value: 2.0E-112
score: 377.8
IPR036554GHMP kinase, C-terminal domain superfamilySUPERFAMILY55060GHMP Kinase, C-terminal domaincoord: 229..378
IPR006205Mevalonate kinaseTIGRFAMTIGR00549TIGR00549coord: 7..342
e-value: 2.8E-80
score: 267.7
IPR006205Mevalonate kinasePANTHERPTHR43290MEVALONATE KINASEcoord: 1..380
IPR006203GHMP kinase, ATP-binding, conserved sitePROSITEPS00627GHMP_KINASES_ATPcoord: 139..150
IPR020568Ribosomal protein S5 domain 2-type foldSUPERFAMILY54211Ribosomal protein S5 domain 2-likecoord: 2..223

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Lag0019921.1Lag0019921.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
biological_process GO:0016310 phosphorylation
biological_process GO:0016126 sterol biosynthetic process
biological_process GO:0008299 isoprenoid biosynthetic process
cellular_component GO:0005737 cytoplasm
molecular_function GO:0005524 ATP binding
molecular_function GO:0004496 mevalonate kinase activity