HG10022546 (gene) Bottle gourd (Hangzhou Gourd) v1

Overview


Name	HG10022546
Type	gene
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	Anaphase-promoting complex subunit 11
Location	Chr05: 25366927 .. 25368276 (-)
RNA-Seq Expression	HG10022546
Synteny	HG10022546

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideCDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGAGGGATGTCCTCTTGGCTATAGAAGGATTTGAGGATGGCAGTGATCTTAAGGACATTTTTTCTAGTGACATAAATGGTGGTGGGCTTGCCCTAGCCAACCTCAAAGATTGGCATATAGTCCTTATCAGTTATCACCAAATGGGTCCGGATTCCCCCATGAAAGAGAGTCTATATAGCCATCATTACTGGTAAATCTTGGATTACCCCATGAAAGAGAGTCTATATAGCCTATCATTACTGGTAAGTCTCATGAAAGAGAGTCTATATAGCCTATCATTACCGGTAAATCTGTACGTGCGGAAACTTCAAAGAAACAGCCCTTGAAAATTTGGTGTTAAATGCAAGTCTCTCTTACAGTTTTATTTGGTTTCAAGATTAGCAGTAGCCATCATATTAGCTTCTAGGGAATGACACTTTTTCCTTCTATTTCCCTGCTTTAAGGTAAGAATTCAGAGGTTTGCAATCATCTCTTTCTACCCTGTCAAATTACTCAGTCTTTCGCTTTCCTCTTACCACAATTCAACTTGAATTGGTATCATCCATGTTCCACAGCTCATGCCACTGAGCAGGTCCTTTTGGGCCACCTCTTCTGAAGCAAGGCAAAGGTTCTTGGAAGTGTCTAGTTTCAAGGTGTTTCGTTGGAAACTTAGCTTAGAAAAAGCCACAAAATCTTTCAAGGAAAAATTTGCAACTTTATGAAATTTGGTAGATTAGTTACTCAACATTTTTACTTGGTGTGCTTTTCTATTACTCTCTTTTGTAATTTAAGTCTTTTTATTATTGCCACTGAAAGGAATTTTCTGTATTCTCTTCGACTTATTTGGGTTGATTTCTTGTCATATGCTTTTGTATCTCTTTTCTCTCGTCATTCTCGACCAAATATAATATGACCATTCCAATTATATACCTGTCAGTATGATAGTTCTGTTGGCTGTTGTACAATATTCATCTGCATCAATACATTAGAAATGGAATCTTTCAATCGACTGCATCTACAATTAGATTTTCTTTGACTCAGATTCCCTCCGTAAACGTATTTTCGGGGTTAAAAAAGAGTACGTTCCCACATTTCTTTTCTTATAGTTCCTACTTGGAGTATAATTAACTACTTTATTATCCTAAGATAATTTCATCCCTTCCGTAAAATATAGGTGGCATGCTGTTGCATCATGGACTTGGAATGCCCAAGACGAAACTTGTGGAATCTGTAGGATGGCCTTTGATGGTTGTTGCCCTGATTGCAAGCTCCCTGGGGATGATTGTCCATTGAGTGAGTCAACTAGCCTTGTCATATCCTCAAACTTTTTCTCCTGCTATCAATCATTGCAACTCACAGTTGATTCTTGA

mRNA sequence

ATGAGGGATGTCCTCTTGGCTATAGAAGGATTTGAGGATGGCAGTGATCTTAAGGACATTTTTTCTAGTGACATAAATGGTGGTGGGCTTGCCCTAGCCAACCTCAAAGATTGGCATATAGTCCTTATCAGTTATCACCAAATGGGTCCGGATTCCCCCATGAAAGAGAGTCTATATAGCCATCATTACTGGTGGCATGCTGTTGCATCATGGACTTGGAATGCCCAAGACGAAACTTGTGGAATCTGTAGGATGGCCTTTGATGGTTGTTGCCCTGATTGCAAGCTCCCTGGGGATGATTGTCCATTGAGTGAGTCAACTAGCCTTGTCATATCCTCAAACTTTTTCTCCTGCTATCAATCATTGCAACTCACAGTTGATTCTTGA

Coding sequence (CDS)

ATGAGGGATGTCCTCTTGGCTATAGAAGGATTTGAGGATGGCAGTGATCTTAAGGACATTTTTTCTAGTGACATAAATGGTGGTGGGCTTGCCCTAGCCAACCTCAAAGATTGGCATATAGTCCTTATCAGTTATCACCAAATGGGTCCGGATTCCCCCATGAAAGAGAGTCTATATAGCCATCATTACTGGTGGCATGCTGTTGCATCATGGACTTGGAATGCCCAAGACGAAACTTGTGGAATCTGTAGGATGGCCTTTGATGGTTGTTGCCCTGATTGCAAGCTCCCTGGGGATGATTGTCCATTGAGTGAGTCAACTAGCCTTGTCATATCCTCAAACTTTTTCTCCTGCTATCAATCATTGCAACTCACAGTTGATTCTTGA

Protein sequence

MRDVLLAIEGFEDGSDLKDIFSSDINGGGLALANLKDWHIVLISYHQMGPDSPMKESLYSHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPLSESTSLVISSNFFSCYQSLQLTVDS

Homology

[Close]

BLAST of HG10022546 vs. NCBI nr
Match: KGN44481.1 (hypothetical protein Csa_016037 [Cucumis sativus])

HSP 1 Score: 109.4 bits (272), Expect = 2.4e-20
Identity = 63/140 (45.00%), Postives = 65/140 (46.43%), Query Frame = 0


Query: 26  NGGGLALANLKDWHIVLISYHQMGPDSPMKESLY--SHHYW------------------- 85
           NGGGLALA LKD +I      QMGPD PMKES +    H W                   
Sbjct: 24  NGGGLALAKLKDANI-----DQMGPDYPMKESTHVPDFHPWNSEVFNLLFYPVELLELLL 83

Query: 86  -----------------------------------------WHAVASWTWNAQDETCGIC 104
                                                    WHAVASWTWNAQDETCGIC
Sbjct: 84  SSSQFSQLSLNWCYPCPTQAIDEIFLDLDALRKRMFGVWKEWHAVASWTWNAQDETCGIC 143

[Close]

BLAST of HG10022546 vs. NCBI nr
Match: XP_035547557.1 (anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547558.1 anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547559.1 anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547674.1 anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547675.1 anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547676.1 anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_040994217.1 anaphase-promoting complex subunit 11 isoform X8 [Juglans microcarpa x Juglans regia] >XP_040994221.1 anaphase-promoting complex subunit 11 isoform X8 [Juglans microcarpa x Juglans regia])

HSP 1 Score: 103.6 bits (257), Expect = 1.3e-18
Identity = 41/44 (93.18%), Postives = 42/44 (95.45%), Query Frame = 0


Query: 60  SHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           S  YWWHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 12  SQLYWWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 55

[Close]

BLAST of HG10022546 vs. NCBI nr
Match: KAF5463602.1 (hypothetical protein F2P56_013763 [Juglans regia] >KAF5464091.1 hypothetical protein F2P56_014198 [Juglans regia])

HSP 1 Score: 103.6 bits (257), Expect = 1.3e-18
Identity = 41/44 (93.18%), Postives = 42/44 (95.45%), Query Frame = 0


Query: 60  SHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           S  YWWHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 32  SQLYWWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 75

[Close]

BLAST of HG10022546 vs. NCBI nr
Match: XP_024926117.1 (anaphase-promoting complex subunit 11-like isoform X1 [Ziziphus jujuba])

HSP 1 Score: 103.2 bits (256), Expect = 1.7e-18
Identity = 40/40 (100.00%), Postives = 40/40 (100.00%), Query Frame = 0


Query: 64  WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 10  WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 49

[Close]

BLAST of HG10022546 vs. NCBI nr
Match: KAG6742543.1 (hypothetical protein POTOM_053415 [Populus tomentosa])

HSP 1 Score: 103.2 bits (256), Expect = 1.7e-18
Identity = 41/49 (83.67%), Postives = 45/49 (91.84%), Query Frame = 0


Query: 55  KESLYSHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           +E L  + +WWHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 231 RELLARNLHWWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 279

[Close]

BLAST of HG10022546 vs. ExPASy Swiss-Prot
Match: Q9M9L0 (Anaphase-promoting complex subunit 11 OS=Arabidopsis thaliana OX=3702 GN=APC11 PE=1 SV=3)

HSP 1 Score: 97.4 bits (241), Expect = 1.2e-19
Identity = 38/39 (97.44%), Postives = 39/39 (100.00%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           WHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 8   WHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 46

[Close]

BLAST of HG10022546 vs. ExPASy Swiss-Prot
Match: Q3ZCF6 (Anaphase-promoting complex subunit 11 OS=Bos taurus OX=9913 GN=ANAPC11 PE=3 SV=1)

HSP 1 Score: 81.3 bits (199), Expect = 9.0e-15
Identity = 30/39 (76.92%), Postives = 34/39 (87.18%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           W+ VA+W W A DE CGICRMAF+GCCPDCK+PGDDCPL
Sbjct: 8   WNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPL 46

[Close]

BLAST of HG10022546 vs. ExPASy Swiss-Prot
Match: Q9NYG5 (Anaphase-promoting complex subunit 11 OS=Homo sapiens OX=9606 GN=ANAPC11 PE=1 SV=1)

HSP 1 Score: 81.3 bits (199), Expect = 9.0e-15
Identity = 30/39 (76.92%), Postives = 34/39 (87.18%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           W+ VA+W W A DE CGICRMAF+GCCPDCK+PGDDCPL
Sbjct: 8   WNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPL 46

[Close]

BLAST of HG10022546 vs. ExPASy Swiss-Prot
Match: Q9CPX9 (Anaphase-promoting complex subunit 11 OS=Mus musculus OX=10090 GN=Anapc11 PE=3 SV=1)

HSP 1 Score: 81.3 bits (199), Expect = 9.0e-15
Identity = 30/39 (76.92%), Postives = 34/39 (87.18%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           W+ VA+W W A DE CGICRMAF+GCCPDCK+PGDDCPL
Sbjct: 8   WNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPL 46

[Close]

BLAST of HG10022546 vs. ExPASy Swiss-Prot
Match: Q5R8A2 (Anaphase-promoting complex subunit 11 OS=Pongo abelii OX=9601 GN=ANAPC11 PE=3 SV=1)

HSP 1 Score: 81.3 bits (199), Expect = 9.0e-15
Identity = 30/39 (76.92%), Postives = 34/39 (87.18%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           W+ VA+W W A DE CGICRMAF+GCCPDCK+PGDDCPL
Sbjct: 8   WNGVATWLWVANDENCGICRMAFNGCCPDCKVPGDDCPL 46

[Close]

BLAST of HG10022546 vs. ExPASy TrEMBL
Match: A0A0A0K9J6 (Anaphase-promoting complex subunit 11 OS=Cucumis sativus OX=3659 GN=Csa_7G306890 PE=4 SV=1)

HSP 1 Score: 109.4 bits (272), Expect = 1.1e-20
Identity = 63/140 (45.00%), Postives = 65/140 (46.43%), Query Frame = 0


Query: 26  NGGGLALANLKDWHIVLISYHQMGPDSPMKESLY--SHHYW------------------- 85
           NGGGLALA LKD +I      QMGPD PMKES +    H W                   
Sbjct: 24  NGGGLALAKLKDANI-----DQMGPDYPMKESTHVPDFHPWNSEVFNLLFYPVELLELLL 83

Query: 86  -----------------------------------------WHAVASWTWNAQDETCGIC 104
                                                    WHAVASWTWNAQDETCGIC
Sbjct: 84  SSSQFSQLSLNWCYPCPTQAIDEIFLDLDALRKRMFGVWKEWHAVASWTWNAQDETCGIC 143

[Close]

BLAST of HG10022546 vs. ExPASy TrEMBL
Match: A0A2I4HDN9 (Anaphase-promoting complex subunit 11 OS=Juglans regia OX=51240 GN=LOC109016305 PE=4 SV=1)

HSP 1 Score: 103.6 bits (257), Expect = 6.2e-19
Identity = 41/44 (93.18%), Postives = 42/44 (95.45%), Query Frame = 0


Query: 60  SHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           S  YWWHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 12  SQLYWWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 55

[Close]

BLAST of HG10022546 vs. ExPASy TrEMBL
Match: A0A6P6FVS8 (Anaphase-promoting complex subunit 11 OS=Ziziphus jujuba OX=326968 GN=LOC107411661 PE=4 SV=1)

HSP 1 Score: 103.2 bits (256), Expect = 8.2e-19
Identity = 40/40 (100.00%), Postives = 40/40 (100.00%), Query Frame = 0


Query: 64  WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 10  WWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 49

[Close]

BLAST of HG10022546 vs. ExPASy TrEMBL
Match: A0A1R3KV27 (Anaphase-promoting complex subunit 11 OS=Corchorus olitorius OX=93759 GN=COLO4_04114 PE=4 SV=1)

HSP 1 Score: 102.4 bits (254), Expect = 1.4e-18
Identity = 44/65 (67.69%), Postives = 49/65 (75.38%), Query Frame = 0


Query: 39  HIVLISYHQMGPDSPMKESLYSHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPG 98
           ++VL S     P++     L  H Y WHAVASWTW+AQDETCGICRMAFDGCC DCKLPG
Sbjct: 8   NLVLHSVEFFSPNAEGTVILVLHEYRWHAVASWTWDAQDETCGICRMAFDGCCSDCKLPG 67

Query: 99  DDCPL 104
           DDCPL
Sbjct: 68  DDCPL 72

[Close]

BLAST of HG10022546 vs. ExPASy TrEMBL
Match: A0A540MMN6 (zf-ANAPC11 domain-containing protein OS=Malus baccata OX=106549 GN=C1H46_014304 PE=4 SV=1)

HSP 1 Score: 102.4 bits (254), Expect = 1.4e-18
Identity = 45/60 (75.00%), Postives = 50/60 (83.33%), Query Frame = 0


Query: 60  SHHYWWHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL--SESTSLVISSNFFS 118
           S H  WHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL  SE  +L +++ F S
Sbjct: 44  SQHLAWHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPLRRSEEEALQVTNVFSS 103

[Close]

BLAST of HG10022546 vs. TAIR 10
Match: AT3G05870.1 (anaphase-promoting complex/cyclosome 11 )

HSP 1 Score: 97.4 bits (241), Expect = 8.6e-21
Identity = 38/39 (97.44%), Postives = 39/39 (100.00%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           WHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 11  WHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 49

[Close]

BLAST of HG10022546 vs. TAIR 10
Match: AT3G05870.2 (anaphase-promoting complex/cyclosome 11 )

HSP 1 Score: 97.4 bits (241), Expect = 8.6e-21
Identity = 38/39 (97.44%), Postives = 39/39 (100.00%), Query Frame = 0


Query: 65  WHAVASWTWNAQDETCGICRMAFDGCCPDCKLPGDDCPL 104
           WHAVASWTW+AQDETCGICRMAFDGCCPDCKLPGDDCPL
Sbjct: 11  WHAVASWTWDAQDETCGICRMAFDGCCPDCKLPGDDCPL 49

[Close]

BLAST of HG10022546 vs. TAIR 10
Match: AT5G26640.1 (BEST Arabidopsis thaliana protein match is: anaphase-promoting complex/cyclosome 11 (TAIR:AT3G05870.2); Has 293 Blast hits to 293 proteins in 137 species: Archae - 0; Bacteria - 0; Metazoa - 128; Fungi - 102; Plants - 41; Viruses - 0; Other Eukaryotes - 22 (source: NCBI BLink). )

HSP 1 Score: 70.1 bits (170), Expect = 1.5e-12
Identity = 27/34 (79.41%), Postives = 30/34 (88.24%), Query Frame = 0


Query: 72  TWNAQDETCGICRMAFDGCCPDCKLPGDDCPLSE 106
           TW+AQDETCG+CRM FD  CPDCKLP DDCPLS+
Sbjct: 5   TWDAQDETCGLCRMPFDASCPDCKLPEDDCPLSK 38

The following BLAST results are available for this feature:

BLAST of HG10022546 vs. NCBI nr


Match Name	E-value	Identity	Description
KGN44481.1	2.4e-20	45.00	hypothetical protein Csa_016037 [Cucumis sativus]	[more]
XP_035547557.1	1.3e-18	93.18	anaphase-promoting complex subunit 11 isoform X7 [Juglans regia] >XP_035547558.1...	[more]
KAF5463602.1	1.3e-18	93.18	hypothetical protein F2P56_013763 [Juglans regia] >KAF5464091.1 hypothetical pro...	[more]
XP_024926117.1	1.7e-18	100.00	anaphase-promoting complex subunit 11-like isoform X1 [Ziziphus jujuba]	[more]
KAG6742543.1	1.7e-18	83.67	hypothetical protein POTOM_053415 [Populus tomentosa]	[more]

BLAST of HG10022546 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9M9L0	1.2e-19	97.44	Anaphase-promoting complex subunit 11 OS=Arabidopsis thaliana OX=3702 GN=APC11 P...	[more]
Q3ZCF6	9.0e-15	76.92	Anaphase-promoting complex subunit 11 OS=Bos taurus OX=9913 GN=ANAPC11 PE=3 SV=1	[more]
Q9NYG5	9.0e-15	76.92	Anaphase-promoting complex subunit 11 OS=Homo sapiens OX=9606 GN=ANAPC11 PE=1 SV...	[more]
Q9CPX9	9.0e-15	76.92	Anaphase-promoting complex subunit 11 OS=Mus musculus OX=10090 GN=Anapc11 PE=3 S...	[more]
Q5R8A2	9.0e-15	76.92	Anaphase-promoting complex subunit 11 OS=Pongo abelii OX=9601 GN=ANAPC11 PE=3 SV...	[more]

BLAST of HG10022546 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A0A0K9J6	1.1e-20	45.00	Anaphase-promoting complex subunit 11 OS=Cucumis sativus OX=3659 GN=Csa_7G306890...	[more]
A0A2I4HDN9	6.2e-19	93.18	Anaphase-promoting complex subunit 11 OS=Juglans regia OX=51240 GN=LOC109016305 ...	[more]
A0A6P6FVS8	8.2e-19	100.00	Anaphase-promoting complex subunit 11 OS=Ziziphus jujuba OX=326968 GN=LOC1074116...	[more]
A0A1R3KV27	1.4e-18	67.69	Anaphase-promoting complex subunit 11 OS=Corchorus olitorius OX=93759 GN=COLO4_0...	[more]
A0A540MMN6	1.4e-18	75.00	zf-ANAPC11 domain-containing protein OS=Malus baccata OX=106549 GN=C1H46_014304 ...	[more]

BLAST of HG10022546 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G05870.1	8.6e-21	97.44	anaphase-promoting complex/cyclosome 11	[more]
AT3G05870.2	8.6e-21	97.44	anaphase-promoting complex/cyclosome 11	[more]
AT5G26640.1	1.5e-12	79.41	BEST Arabidopsis thaliana protein match is: anaphase-promoting complex/cyclosome...	[more]

InterPro

Analysis Name: InterPro Annotations of Bottle gourd (Hangzhou Gourd) v1
Date Performed: 2022-08-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	3.30.40.10	Zinc/RING finger domain, C3HC4 (zinc finger)	coord: 51..113 e-value: 3.7E-9 score: 38.6
IPR024991	Anaphase-promoting complex subunit 11, RING-H2 finger	PFAM	PF12861	zf-ANAPC11	coord: 65..104 e-value: 9.2E-18 score: 64.1
None	No IPR available	PANTHER	PTHR11210	RING BOX	coord: 64..104
None	No IPR available	PANTHER	PTHR11210:SF1	ANAPHASE-PROMOTING COMPLEX SUBUNIT 11	coord: 64..104
None	No IPR available	SUPERFAMILY	57850	RING/U-box	coord: 64..103

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
HG10022546.1	HG10022546.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0031145	anaphase-promoting complex-dependent catabolic process
biological_process	GO:0051301	cell division
biological_process	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
biological_process	GO:0016567	protein ubiquitination
cellular_component	GO:0005680	anaphase-promoting complex
molecular_function	GO:0097602	cullin family protein binding
molecular_function	GO:0061630	ubiquitin protein ligase activity
molecular_function	GO:0008270	zinc ion binding