HG10022528 (gene) Bottle gourd (Hangzhou Gourd) v1

Overview
NameHG10022528
Typegene
OrganismLagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Descriptiondehydrogenase/reductase SDR family member 12
LocationChr05: 25137140 .. 25140898 (+)
RNA-Seq ExpressionHG10022528
SyntenyHG10022528
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSpolypeptide
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGAATTTGGAGCTCTGCAGCTTCGAATCCACATTTCCATTGGAGCACTCGCCATGTTTCTTCTCAATGTAAATACTCTTTTCTCTTCTCAAATCATCTTTTTTAATTCTGAGTTTTCTTTTGCTACACCACCCAAATCTTTGATTCTGTGATCCGATTTTTGTATTTTGAGCTCTTACTCTATTCCCCTTCTTGCTTGCAGGCATGGAGACGCTCAGCTTTTGGGGTCTATGGCTACCTCAACTTCACCAAATCTGCATACATGTAATTTAGTCTCTATGGTTTGATTAAATTTGTGGAGGCAACAAGGAACTCTTACCCCTTTTTTGTCTTAATTTTTTGTTAAATTATATTTTTGGTTCCTATAGTTTGGAGAAAGTTAGAGTTTAGTCTATGTGGTTTCAAAAGTTAGAATTTAATCTCTATGGTTGGATAAATCTTCATAAGTAGTTCGTGATGAAACTTAGAGATTATTTAGGACAGTTTTATCACATCGTAGAGATTAAATTCTAATTATAAACTAAATTTTAACTTTCTTTTCCATGAAAGTTGTTTGATTGGGTCATCTAGAAGGGAAACTTGCATTGGAAATTAGGAAACTACCCTTGTGAGTTTCATTTCGAAATCGAAGGATAGGAGGAATTTGAATTGAATTAGATAGTACAAAGTGCTTAGCTAAGGAATACTTCTTTTAGAAACAACTTTTGTCCAAAACCTTGATTATTTCACTTTGTTTATGGTGGTTTGTCTACTGATCTAACACATTCTTTAGATGTTTACTTTCTTGAAGAAATTCAAGTTGGGATTTTAGGATACTTACCTCCTAACTAGAACACTCAAGAACACTAAAAGATAGATTCATATTGCAATGTGAACGAAAAACTATAATTTAACATAGTCTTTTGAGAGGGCTACTCTTACCCTAATTCTCCAAAGGAAATCCCGCAAAATTTTCCACACTTTGCTCCCAACCCCACTCCCTCTATTTATAACTAAAAGCTCTACCAAACTTCCTGTCTATTTACTAATTTGCCCCTTCTAATAACCATACCAATATTCTACTAATAGTTTCATAACTACGCTAAATCTAACAGATTTGAGGTCAAAGCATACTTAGTCTTTCATTCATAGTTGCACTGATTATTAGAGGTTTTTGTGATGTTAAATCATTAACAACTTTTCAATATGTTTTTAATTTCTTTAACGTGATTAACTCTTGACTGTTTTATGGCTATAGTGAACATTCTAATAAGTTCAAACCAGAGGATATGCAAATGGACATTGAAGGGAAAAATTGCATTGTTACTGGGGCGAATTCCGGGATTGGATATGCAACTGCAGAGGGTTTAGCATCACGGTATTGATCTCTTTTTCCGATTCTTGTTTTGATTTCTGTTAAATTTGTCAAGTCGACAAGGAACAAAACTTCTGTAAGAACAATAGTGATTCATTATTGTGGAAGCATGAAATTTCTTCTGTTTTTGCAGTGGAGCTACCGTCTACATGGTATGCCGCAACAAGGAAAGAGGAGAAGCTGCTCTTTCTGAGATAAAGTCTAAAACAGGAAACCAAAATATTCATTTGGAGGTAGTTCTTTTCCAACCACCATTCACAACAGAATGTGGTTTCTAACTTTCTATAGCAAATCTGATTTCAAAATTGAAATCGTGCTCGCTTCTAGGAGTCCTTAGCATTGTATTTCCTACTTTGTGCTGGTCATCTTGACCTTTTTGTAACTCTTTTCTTGTAGATGATATTTGTGGCAGACCTTTTAGGTTATGCTATATTTAATAGTATTTTGGGATAGTTTAAATGATATGATAGTAGGTTTGTCTCAATTTAACTATGGGATAATTAGCCAAAGTGAGCATAATTTTACTAGCATATAGATGAGTTAGCGACCACGAAGTCTATGGTTCGAATTCTCCTACCCCTATTGTAACTAGAAGCAGTGCAGTTACCTACTAATTCTATTATCAAGTTTGGTTTTGTTTTTAAAAGAATACATTACAACTTTAGCTTTCTTGTTACTTAATAACTCTTCTTTAGTTTGCAGATCTGTGATCTTTCCTCAATCAGTGACATTAAGTCATTTTCCTCCGATTTTATTACAAAGAATGTCCCAGTCCATGTTTTGGTAATGAATCTGCCTTTGTAACATTTGCCTTTTATGTGCTAAAAATTGTATGCTTTAGCCCATTTTTTGCATTATATCTGCAAAATCATTACCATTTACTAACTGTATATAGGTTAACAATGCTGGGTTGCTTGAGAAAAACCGAATTACGACGTCTGAAGGGTAGGGTCTCCTTTATTTGTCTGCTTCACTAGGCTCTTCTCTCTATCTGTAACTTTTTGAGTTGCCACAAATTCTTAATAATTTCTGAATTCCAGGTTCGAATTGAACTTTGCTGTGAATGTTTTAGGCACTTATGCAATGACTGAATCAGTGTTGCCATTGCTGGAGAAAGCTGCACCTGATGCAAAGGTCATCACAGTTTCTTCTGGTGGAATGTATTCAGTTCCCTTAACCAATGATCTGCAGGTGGGTTTCCTTTTTAAACTTCTCTGCCTTCCCAATTTGCAGATCTCATTCTTACTGGCTCTTTTATTTGTTTCCTTGTAGTTTAGTGAAGAAAATTTTGATGGGGTCAAACAGTATGCACTTAACAAACGAGTTCAGGTTAGTAATGCTCGATATCTTGTCTTCTAAAATCACTATGTTTTTTATTTACTGTATGGTGTAAGAATGCATTGTTTTAGGTTTCACTCACACATGTTAAAAATTTTGGTTCTTTTTAATAGGAATAACCGAACTTTCATTGAGAAAAGAAAATGTAAGAATACAAGGCATAAAAGATTAAAAAAATTAAACCCACCAAAAGAGAGCCATACTATAAAAAAGGGCTCCGGTGGAGTAAAATAAGACTTATAGGATAGTTACAAAAAAGGGTCACCATCAAAGCCCAAAGAAAAACATAAGACCTATAGGATATTTGATAACTTTACAAAGGACCAAACATTAATTGAAATCATTTCAAATCCTCTAAAGCTTCTATTGTTCTTCTCACTCTGAAGACCCCACAAAACTGTACACACTCTGGCTCGTCAAAAAAATCTCTTCTTGCGAAAGTGTGGGTGAAGAAGGAACTCCTCTTAATCTTGTTGCATAACCTAGGCCTAGCAAAACAGAAGCCAAATGCCTCAGATAAATAACCCAACAAAGTGTCATGGATAGATGAGTAATGTAACCTCGCTTGACACTGTTAAGATGGCTTGATTTAGCCATTGTTGCATTCTGTTCTGAGATAGCTTAAGGTGAGTGAAGCTTCCTTTTCAGGTGGCTTTAACAGAGAAATGGGCAGAGATATACTCTAACAAAGGGATTGGATTCTACTCAATGCACCCCGGTTGGGCTGAAACACCCGGAGTGACTAAATCTTTACCAAGTTTCTCTAAATCGTAAGAATGGCCTAGAAAAATCTTTGTTCTTCAAAATGGACTTAGAATAGTTCTCGATTATCATTTCGCCGTTTGATCATTTCAGGCTCTCGGGGAAGCTAAGAACGAGCGAGGAAGGGGCCGATACGATTATTTGGTTGGCTTTACAGCCAAAAGAGAAGTTGGTACCTGGAGCATTCTACTTTGATAGAAGTGAAGCACCAAAGCATTTAGCGTTTGCTGCTACAAAGTCTTCTCATACAGCAATTGGCTCTATATATGATCATCTTCGTTCTTTGTCTGGTTTGGCTCAGTAA

mRNA sequence

ATGGAATTTGGAGCTCTGCAGCTTCGAATCCACATTTCCATTGGAGCACTCGCCATGTTTCTTCTCAATGCATGGAGACGCTCAGCTTTTGGGGTCTATGGCTACCTCAACTTCACCAAATCTGCATACATTGAACATTCTAATAAGTTCAAACCAGAGGATATGCAAATGGACATTGAAGGGAAAAATTGCATTGTTACTGGGGCGAATTCCGGGATTGGATATGCAACTGCAGAGGGTTTAGCATCACGTGGAGCTACCGTCTACATGGTATGCCGCAACAAGGAAAGAGGAGAAGCTGCTCTTTCTGAGATAAAGTCTAAAACAGGAAACCAAAATATTCATTTGGAGATCTGTGATCTTTCCTCAATCAGTGACATTAAGTCATTTTCCTCCGATTTTATTACAAAGAATGTCCCAGTCCATGTTTTGGTTAACAATGCTGGGTTGCTTGAGAAAAACCGAATTACGACGTCTGAAGGGTTCGAATTGAACTTTGCTGTGAATGTTTTAGGCACTTATGCAATGACTGAATCAGTGTTGCCATTGCTGGAGAAAGCTGCACCTGATGCAAAGGTCATCACAGTTTCTTCTGGTGGAATGTATTCAGTTCCCTTAACCAATGATCTGCAGTTTAGTGAAGAAAATTTTGATGGGGTCAAACAGTATGCACTTAACAAACGAGTTCAGGTGGCTTTAACAGAGAAATGGGCAGAGATATACTCTAACAAAGGGATTGGATTCTACTCAATGCACCCCGGTTGGGCTGAAACACCCGGAGTGACTAAATCTTTACCAAGTTTCTCTAAATCGCTCTCGGGGAAGCTAAGAACGAGCGAGGAAGGGGCCGATACGATTATTTGGTTGGCTTTACAGCCAAAAGAGAAGTTGGTACCTGGAGCATTCTACTTTGATAGAAGTGAAGCACCAAAGCATTTAGCGTTTGCTGCTACAAAGTCTTCTCATACAGCAATTGGCTCTATATATGATCATCTTCGTTCTTTGTCTGGTTTGGCTCAGTAA

Coding sequence (CDS)

ATGGAATTTGGAGCTCTGCAGCTTCGAATCCACATTTCCATTGGAGCACTCGCCATGTTTCTTCTCAATGCATGGAGACGCTCAGCTTTTGGGGTCTATGGCTACCTCAACTTCACCAAATCTGCATACATTGAACATTCTAATAAGTTCAAACCAGAGGATATGCAAATGGACATTGAAGGGAAAAATTGCATTGTTACTGGGGCGAATTCCGGGATTGGATATGCAACTGCAGAGGGTTTAGCATCACGTGGAGCTACCGTCTACATGGTATGCCGCAACAAGGAAAGAGGAGAAGCTGCTCTTTCTGAGATAAAGTCTAAAACAGGAAACCAAAATATTCATTTGGAGATCTGTGATCTTTCCTCAATCAGTGACATTAAGTCATTTTCCTCCGATTTTATTACAAAGAATGTCCCAGTCCATGTTTTGGTTAACAATGCTGGGTTGCTTGAGAAAAACCGAATTACGACGTCTGAAGGGTTCGAATTGAACTTTGCTGTGAATGTTTTAGGCACTTATGCAATGACTGAATCAGTGTTGCCATTGCTGGAGAAAGCTGCACCTGATGCAAAGGTCATCACAGTTTCTTCTGGTGGAATGTATTCAGTTCCCTTAACCAATGATCTGCAGTTTAGTGAAGAAAATTTTGATGGGGTCAAACAGTATGCACTTAACAAACGAGTTCAGGTGGCTTTAACAGAGAAATGGGCAGAGATATACTCTAACAAAGGGATTGGATTCTACTCAATGCACCCCGGTTGGGCTGAAACACCCGGAGTGACTAAATCTTTACCAAGTTTCTCTAAATCGCTCTCGGGGAAGCTAAGAACGAGCGAGGAAGGGGCCGATACGATTATTTGGTTGGCTTTACAGCCAAAAGAGAAGTTGGTACCTGGAGCATTCTACTTTGATAGAAGTGAAGCACCAAAGCATTTAGCGTTTGCTGCTACAAAGTCTTCTCATACAGCAATTGGCTCTATATATGATCATCTTCGTTCTTTGTCTGGTTTGGCTCAGTAA

Protein sequence

MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESVLPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEIYSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPGAFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ
Homology
BLAST of HG10022528 vs. NCBI nr
Match: XP_038899726.1 (dehydrogenase/reductase SDR family member 12 [Benincasa hispida])

HSP 1 Score: 633.6 bits (1633), Expect = 9.5e-178
Identity = 316/340 (92.94%), Postives = 329/340 (96.76%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME  ALQ+RIHISIGALAMFLL AWR SAFGVYGYLNFTKSA+IEHS KFKPEDMQ +IE
Sbjct: 1   MEPAALQVRIHISIGALAMFLLKAWRFSAFGVYGYLNFTKSAFIEHSKKFKPEDMQTNIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI DIKSFS+ FI+KNVPVHVLVNNAGL+EKNR+TTSEGFELNFAVNVLGTYAMTES+
Sbjct: 121 LSSIRDIKSFSTKFISKNVPVHVLVNNAGLIEKNRVTTSEGFELNFAVNVLGTYAMTESM 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           LPLLEKAAPD KVITVSSGGMYSVPLTNDLQFSE+ FDGVKQYA NKRVQVALTEKWAE+
Sbjct: 181 LPLLEKAAPDGKVITVSSGGMYSVPLTNDLQFSEDEFDGVKQYAFNKRVQVALTEKWAEM 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADT+IWLALQPKEKLVPG
Sbjct: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTLIWLALQPKEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ
Sbjct: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. NCBI nr
Match: XP_008461902.1 (PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Cucumis melo] >XP_016902772.1 PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Cucumis melo] >XP_016902773.1 PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Cucumis melo])

HSP 1 Score: 619.0 bits (1595), Expect = 2.4e-173
Identity = 310/340 (91.18%), Postives = 324/340 (95.29%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME   LQLRIHISIG LAMFLL AWR SAFGVYGYLNFTKSA+IEHS  FKPEDMQ +IE
Sbjct: 1   MEAATLQLRIHISIGTLAMFLLKAWRLSAFGVYGYLNFTKSAFIEHSKMFKPEDMQTNIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYM+CR+KERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMICRSKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI DIKSFSS+FI+KNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTES+
Sbjct: 121 LSSIRDIKSFSSNFISKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESL 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           LPLLEKAAPDAKVITVSSGGMYSVPLT+DLQFSE+ FDG  QYALNKRVQVALTEKWAE+
Sbjct: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTDDLQFSEDQFDGAIQYALNKRVQVALTEKWAEM 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YS KGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG
Sbjct: 241 YSKKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDR  APKHLAFAAT+SSHTA+GSIYDHLRSLSGLAQ
Sbjct: 301 AFYFDRRVAPKHLAFAATQSSHTAMGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. NCBI nr
Match: XP_004139691.1 (dehydrogenase/reductase SDR family member 12 [Cucumis sativus])

HSP 1 Score: 614.8 bits (1584), Expect = 4.6e-172
Identity = 307/340 (90.29%), Postives = 321/340 (94.41%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME   LQLRIHISIG LAMFLL AWR SAFGVYGYLNFTKSA+IEHS KFKPEDMQ +IE
Sbjct: 1   MEAATLQLRIHISIGTLAMFLLKAWRVSAFGVYGYLNFTKSAFIEHSKKFKPEDMQTNIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGA+VYM+CRNKERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGASVYMICRNKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSISDIKSFSS FI+KNVPVHVLVNNAG+LEKNRITT EGFE NFAVNVLGTYAMTES+
Sbjct: 121 LSSISDIKSFSSKFISKNVPVHVLVNNAGMLEKNRITTPEGFEFNFAVNVLGTYAMTESL 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSE+ FDGV QYA NKRVQVALTEKW+E+
Sbjct: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEDEFDGVVQYARNKRVQVALTEKWSEM 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YS KGIGFYSMHPGWAETPG TKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKL PG
Sbjct: 241 YSKKGIGFYSMHPGWAETPGATKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLEPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AF+FDR  APKHLAFAATKSSHTA+GSIYDHLRSLSGLAQ
Sbjct: 301 AFFFDRMVAPKHLAFAATKSSHTAMGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. NCBI nr
Match: XP_023535216.1 (dehydrogenase/reductase SDR family member 12 isoform X2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 613.2 bits (1580), Expect = 1.3e-171
Identity = 305/340 (89.71%), Postives = 319/340 (93.82%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME GALQ+R+HISIGALAMFLL AWR S FG YGYLNFTKSA+ EHS  FKPEDMQ +IE
Sbjct: 1   MERGALQVRVHISIGALAMFLLKAWRVSVFGAYGYLNFTKSAFSEHSKMFKPEDMQANIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI D+ SFSS+FI+KNVPVHVLVNNAGLLE NR+TTSEGFELNFAVNVLGTYA+TE +
Sbjct: 121 LSSIRDVTSFSSNFISKNVPVHVLVNNAGLLENNRVTTSEGFELNFAVNVLGTYAITELM 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           +PLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEE FDG KQYALNKRVQVALTEKWAE 
Sbjct: 181 MPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEEKFDGAKQYALNKRVQVALTEKWAEK 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGV KSLPSF+KSLSGKLRT EEGADTIIWLALQP EKLVPG
Sbjct: 241 YSNKGIGFYSMHPGWAETPGVAKSLPSFTKSLSGKLRTREEGADTIIWLALQPNEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDRSEAPKHLAFAATKSSH  IGSIYDHLRSLSGLAQ
Sbjct: 301 AFYFDRSEAPKHLAFAATKSSHATIGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. NCBI nr
Match: KAG6592207.1 (Dehydrogenase/reductase SDR family member 12, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 612.5 bits (1578), Expect = 2.3e-171
Identity = 305/340 (89.71%), Postives = 319/340 (93.82%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME GALQ+R+ ISIGALAMFLL AWR S FG YGYLNFTKSA+ EHS  FKPEDMQ +IE
Sbjct: 13  MERGALQVRVSISIGALAMFLLKAWRVSVFGAYGYLNFTKSAFSEHSKMFKPEDMQANIE 72

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 73  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNVHLEVCD 132

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI D+KSFSS+FI+KNVPVHVLVNNAGLLE NR+TTSEGFELNFAVNVLGTYAMTE +
Sbjct: 133 LSSIRDVKSFSSNFISKNVPVHVLVNNAGLLENNRVTTSEGFELNFAVNVLGTYAMTELM 192

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           +PLLEKAAPDAKVITVSSGGMY+VPLTNDLQFSEE FDG KQYALNKRVQVALTEKWAE 
Sbjct: 193 MPLLEKAAPDAKVITVSSGGMYTVPLTNDLQFSEEKFDGAKQYALNKRVQVALTEKWAEK 252

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGV KSLPSF+KSLSGKLRT EEGADTIIWLALQP EKLVPG
Sbjct: 253 YSNKGIGFYSMHPGWAETPGVAKSLPSFTKSLSGKLRTREEGADTIIWLALQPNEKLVPG 312

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDRSEAPKHLAFAATKSSH  IGSIYDHLRSLSGLAQ
Sbjct: 313 AFYFDRSEAPKHLAFAATKSSHATIGSIYDHLRSLSGLAQ 352

BLAST of HG10022528 vs. ExPASy Swiss-Prot
Match: A6QP05 (Dehydrogenase/reductase SDR family member 12 OS=Bos taurus OX=9913 GN=DHRS12 PE=2 SV=1)

HSP 1 Score: 248.8 bits (634), Expect = 8.7e-65
Identity = 140/314 (44.59%), Postives = 188/314 (59.87%), Query Frame = 0

Query: 25  WRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIEGKNCIVTGANSGIGYATAEGLASR 84
           +R +A+   G   +TKS Y   S  F P+D+++ + G+  +VTG NSGIG ATA  +A R
Sbjct: 4   YRSAAWFAKGLREYTKSGYESASKDFVPDDLEVQVPGRAFMVTGGNSGIGKATAMEIAKR 63

Query: 85  GATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICDLSSISDIKSFSSDFITKNVPVHVL 144
           G TV++VCR+  R E A +EI  ++GNQNI L I DLS    +  F  +F  ++  ++VL
Sbjct: 64  GGTVHLVCRDHSRAEGAKAEIIRESGNQNIFLHIVDLSLPKSVWKFVENFKQEHT-LNVL 123

Query: 145 VNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESVLPLLEKAAPDAKVITVSSGGMYSV 204
           +NNAG +   R  T +G E NFA N LG Y +T +++P+LEK   D +VITVSSGGM   
Sbjct: 124 INNAGCMVNKRELTEDGLEKNFATNTLGVYVLTTALIPVLEK-EHDPRVITVSSGGMLVQ 183

Query: 205 PL-TNDLQFSEENFDGVKQYALNKRVQVALTEKWAEIYSNKGIGFYSMHPGWAETPGVTK 264
            L T+D Q     FDG   YA NKR QV LTE+WA   ++  I F  MHPGW +TPGV  
Sbjct: 184 KLNTDDPQSERTAFDGTMVYAQNKRQQVVLTERWAR--AHPAIHFSCMHPGWVDTPGVRL 243

Query: 265 SLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVP-GAFYFDRSEAPKHLAFAATKSSH 324
           S+P F   L  +LR+  +GADT++WLAL P     P G F+ DR  AP HL  A T SS 
Sbjct: 244 SMPGFHARLGARLRSEAQGADTVLWLALAPAATAQPSGCFFQDRKPAPTHLPLARTSSSP 303

Query: 325 TAIGSIYDHLRSLS 337
                + + L  L+
Sbjct: 304 AEEEKLIEILEELA 313

BLAST of HG10022528 vs. ExPASy Swiss-Prot
Match: A0PJE2 (Dehydrogenase/reductase SDR family member 12 OS=Homo sapiens OX=9606 GN=DHRS12 PE=2 SV=2)

HSP 1 Score: 240.0 bits (611), Expect = 4.0e-62
Identity = 138/317 (43.53%), Postives = 183/317 (57.73%), Query Frame = 0

Query: 22  LNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIEGKNCIVTGANSGIGYATAEGL 81
           ++ +R   +   G   +TKS Y      F P D+++ I G+  +VTG NSGIG ATA  +
Sbjct: 1   MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEI 60

Query: 82  ASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICDLSSISDIKSFSSDFITKNVPV 141
           A RG TV++VCR++   E A  EI  ++GNQNI L I DLS    I  F  +F  ++  +
Sbjct: 61  AKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEH-KL 120

Query: 142 HVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESVLPLLEKAAPDAKVITVSSGGM 201
           HVL+NNAG +   R  T +G E NFA N LG Y +T  ++P+LEK   D +VITVSSGGM
Sbjct: 121 HVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEK-EHDPRVITVSSGGM 180

Query: 202 YSVPL-TNDLQFSEENFDGVKQYALNKRVQVALTEKWAEIYSNKGIGFYSMHPGWAETPG 261
               L TNDLQ     FDG   YA NKR QV LTE+WA+   +  I F SMHPGWA+TPG
Sbjct: 181 LVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQ--GHPAIHFSSMHPGWADTPG 240

Query: 262 VTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVP-GAFYFDRSEAPKHLAFAATK 321
           V +++P F      +LR+  +GADT++WLAL       P G F+ DR     HL  A   
Sbjct: 241 VRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATAS 300

Query: 322 SSHTAIGSIYDHLRSLS 337
           SS      + + L  L+
Sbjct: 301 SSPAEEEKLIEILEQLA 313

BLAST of HG10022528 vs. ExPASy Swiss-Prot
Match: Q8TC12 (Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2)

HSP 1 Score: 137.9 bits (346), Expect = 2.2e-31
Identity = 90/287 (31.36%), Postives = 157/287 (54.70%), Query Frame = 0

Query: 57  MDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHL 116
           + + GK  +VTGAN+GIG  TA+ LA RGA VY+ CR+ E+GE    EI++ TGNQ + +
Sbjct: 37  VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLV 96

Query: 117 EICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAM 176
              DLS    I++F+  F+ +   +HVL+NNAG++      T++GFE++  VN LG + +
Sbjct: 97  RKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLL 156

Query: 177 TESVLPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEK 236
           T  +L  L+++AP ++++ VSS   +   +       E+ ++    Y  +K   +  T++
Sbjct: 157 THLLLEKLKESAP-SRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQE 216

Query: 237 WAEIYSNKGIGFYSMHPGWAETPGVTKSLPSFSKSL----SGKLRTSEEGADTIIWLALQ 296
            A      G+  YS+HPG  ++  V  S  SF + +    S  ++T ++GA T +  AL 
Sbjct: 217 LARRLKGSGVTTYSVHPGTVQSELVRHS--SFMRWMWWLFSFFIKTPQQGAQTSLHCALT 276

Query: 297 PKEKLVPGAFYFDRSEAPKHLAFAATKSSHTAIG-SIYDHLRSLSGL 339
              +++ G  + D      H+A+ + ++ +  I   ++D    L GL
Sbjct: 277 EGLEILSGNHFSD-----CHVAWVSAQARNETIARRLWDVSCDLLGL 315

BLAST of HG10022528 vs. ExPASy Swiss-Prot
Match: Q9QYF1 (Retinol dehydrogenase 11 OS=Mus musculus OX=10090 GN=Rdh11 PE=1 SV=2)

HSP 1 Score: 136.7 bits (343), Expect = 4.8e-31
Identity = 79/251 (31.47%), Postives = 141/251 (56.18%), Query Frame = 0

Query: 57  MDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHL 116
           + + GK  IVTGAN+GIG  TA+ LA RGA VY+ CR+ ++GE A  EI++ TGN  + +
Sbjct: 34  VQLPGKVAIVTGANTGIGKETAKDLAQRGARVYLACRDVDKGELAAREIQAVTGNSQVFV 93

Query: 117 EICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAM 176
              DL+    I++F+ DF+ +   +H+L+NNAG++      T++GFE++  VN LG + +
Sbjct: 94  RKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLL 153

Query: 177 TESVLPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEK 236
           T  +L  L+++AP ++++ +SS G +   +       E+ +     Y  +K   +  T++
Sbjct: 154 THLLLEKLKESAP-SRIVNLSSLGHHLGRIHFHNLQGEKFYSAGLAYCHSKLANILFTKE 213

Query: 237 WAEIYSNKGIGFYSMHPG--WAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPK 296
            A+     G+  YS+HPG   +E    +  +    +     ++T +EGA T ++ AL   
Sbjct: 214 LAKRLKGSGVTTYSVHPGTVHSELTRYSSIMRWLWQLFFVFIKTPQEGAQTSLYCALTEG 273

Query: 297 EKLVPGAFYFD 306
            + + G+ + D
Sbjct: 274 LESLSGSHFSD 283

BLAST of HG10022528 vs. ExPASy Swiss-Prot
Match: Q96NR8 (Retinol dehydrogenase 12 OS=Homo sapiens OX=9606 GN=RDH12 PE=1 SV=3)

HSP 1 Score: 135.6 bits (340), Expect = 1.1e-30
Identity = 88/253 (34.78%), Postives = 141/253 (55.73%), Query Frame = 0

Query: 57  MDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHL 116
           + + GK  ++TGAN+GIG  TA  LASRGA VY+ CR+  +GE+A SEI+  T N  + +
Sbjct: 35  VQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLV 94

Query: 117 EICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAM 176
              DLS    I++F+  F+ +   +H+L+NNAG++      T++GFE +  VN LG + +
Sbjct: 95  RKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLL 154

Query: 177 TESVLPLLEKAAPDAKVITVSSGGMY--SVPLTNDLQFSEENFDGVKQYALNKRVQVALT 236
           T  +L  L+ +AP A+V+ VSS   +   +P  +DLQ SE+ +     Y  +K   V  T
Sbjct: 155 TYLLLERLKVSAP-ARVVNVSSVAHHIGKIPF-HDLQ-SEKRYSRGFAYCHSKLANVLFT 214

Query: 237 EKWAEIYSNKGIGFYSMHPGWAETPGVTKS--LPSFSKSLSGKLRTSEEGADTIIWLALQ 296
            + A+     G+  Y++HPG   +  V  S  L    +  S  ++T+ EGA T +  AL 
Sbjct: 215 RELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLFSPFVKTAREGAQTSLHCALA 274

Query: 297 PKEKLVPGAFYFD 306
              + + G ++ D
Sbjct: 275 EGLEPLSGKYFSD 284

BLAST of HG10022528 vs. ExPASy TrEMBL
Match: A0A1S4E3H2 (dehydrogenase/reductase SDR family member 12 isoform X1 OS=Cucumis melo OX=3656 GN=LOC103500396 PE=4 SV=1)

HSP 1 Score: 619.0 bits (1595), Expect = 1.2e-173
Identity = 310/340 (91.18%), Postives = 324/340 (95.29%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME   LQLRIHISIG LAMFLL AWR SAFGVYGYLNFTKSA+IEHS  FKPEDMQ +IE
Sbjct: 1   MEAATLQLRIHISIGTLAMFLLKAWRLSAFGVYGYLNFTKSAFIEHSKMFKPEDMQTNIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYM+CR+KERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMICRSKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI DIKSFSS+FI+KNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTES+
Sbjct: 121 LSSIRDIKSFSSNFISKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESL 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           LPLLEKAAPDAKVITVSSGGMYSVPLT+DLQFSE+ FDG  QYALNKRVQVALTEKWAE+
Sbjct: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTDDLQFSEDQFDGAIQYALNKRVQVALTEKWAEM 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YS KGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG
Sbjct: 241 YSKKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDR  APKHLAFAAT+SSHTA+GSIYDHLRSLSGLAQ
Sbjct: 301 AFYFDRRVAPKHLAFAATQSSHTAMGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. ExPASy TrEMBL
Match: A0A6J1F992 (dehydrogenase/reductase SDR family member 12 OS=Cucurbita moschata OX=3662 GN=LOC111443262 PE=4 SV=1)

HSP 1 Score: 612.1 bits (1577), Expect = 1.4e-171
Identity = 305/340 (89.71%), Postives = 319/340 (93.82%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME GALQ+R+HISIGALAMFLL AWR S FG YGYLNFTKSA+ EHS  FKPEDMQ +IE
Sbjct: 1   MERGALQVRVHISIGALAMFLLKAWRVSVFGAYGYLNFTKSAFSEHSKMFKPEDMQANIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI D+KSFSS+FI+KNVPVHVLVNNAGLLE NR+TTSEGFELNFAVNVLGTYA+TE +
Sbjct: 121 LSSIRDVKSFSSNFISKNVPVHVLVNNAGLLENNRVTTSEGFELNFAVNVLGTYAITELM 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           +PLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSE  FDG KQYALNKRVQVALTEKWAE 
Sbjct: 181 MPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEVKFDGAKQYALNKRVQVALTEKWAEK 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGV KSLPSF+KSLSGKLRT EEGADTIIWLALQP EKLVPG
Sbjct: 241 YSNKGIGFYSMHPGWAETPGVAKSLPSFTKSLSGKLRTREEGADTIIWLALQPNEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLAQ 341
           AFYFDRSEAPKHLAF+ATKSSH  IGSIYDHLRSLSGLAQ
Sbjct: 301 AFYFDRSEAPKHLAFSATKSSHATIGSIYDHLRSLSGLAQ 340

BLAST of HG10022528 vs. ExPASy TrEMBL
Match: A0A6J1IKU6 (dehydrogenase/reductase SDR family member 12 isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC111477154 PE=4 SV=1)

HSP 1 Score: 609.0 bits (1569), Expect = 1.2e-170
Identity = 304/339 (89.68%), Postives = 316/339 (93.22%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME GALQ+R  ISIG LAMFLL AWR S FG YGYLNFTKSA+ EHS  FKPEDMQ +IE
Sbjct: 1   MERGALQVRFSISIGGLAMFLLKAWRVSVFGAYGYLNFTKSAFSEHSKMFKPEDMQANIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQN+HLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNVHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSSI D+KSFSS+FI+KNVPVHVLVNNAGLLE NR+TTSEGFELNFAVNVLGTYAMTE +
Sbjct: 121 LSSIRDVKSFSSNFISKNVPVHVLVNNAGLLENNRVTTSEGFELNFAVNVLGTYAMTELM 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           +PLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEE FDG KQYALNKRVQVALTEKWAE 
Sbjct: 181 MPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEEKFDGAKQYALNKRVQVALTEKWAEK 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGV KSLPSF+KSLSGKLRT EEGADTIIWLALQP EKLVPG
Sbjct: 241 YSNKGIGFYSMHPGWAETPGVAKSLPSFTKSLSGKLRTREEGADTIIWLALQPNEKLVPG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLA 340
           AFYFDRSEAPKHLAFAATKSSH  IGSIYDHLRSLSGLA
Sbjct: 301 AFYFDRSEAPKHLAFAATKSSHATIGSIYDHLRSLSGLA 339

BLAST of HG10022528 vs. ExPASy TrEMBL
Match: A0A6J1INJ9 (dehydrogenase/reductase SDR family member 12 isoform X1 OS=Cucurbita maxima OX=3661 GN=LOC111477154 PE=4 SV=1)

HSP 1 Score: 600.9 bits (1548), Expect = 3.3e-168
Identity = 304/349 (87.11%), Postives = 316/349 (90.54%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLN----------AWRRSAFGVYGYLNFTKSAYIEHSNKF 60
           ME GALQ+R  ISIG LAMFLL           AWR S FG YGYLNFTKSA+ EHS  F
Sbjct: 1   MERGALQVRFSISIGGLAMFLLKACTLLRSSLCAWRVSVFGAYGYLNFTKSAFSEHSKMF 60

Query: 61  KPEDMQMDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTG 120
           KPEDMQ +IEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTG
Sbjct: 61  KPEDMQANIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTG 120

Query: 121 NQNIHLEICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNV 180
           NQN+HLE+CDLSSI D+KSFSS+FI+KNVPVHVLVNNAGLLE NR+TTSEGFELNFAVNV
Sbjct: 121 NQNVHLEVCDLSSIRDVKSFSSNFISKNVPVHVLVNNAGLLENNRVTTSEGFELNFAVNV 180

Query: 181 LGTYAMTESVLPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQ 240
           LGTYAMTE ++PLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEE FDG KQYALNKRVQ
Sbjct: 181 LGTYAMTELMMPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEEKFDGAKQYALNKRVQ 240

Query: 241 VALTEKWAEIYSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLA 300
           VALTEKWAE YSNKGIGFYSMHPGWAETPGV KSLPSF+KSLSGKLRT EEGADTIIWLA
Sbjct: 241 VALTEKWAEKYSNKGIGFYSMHPGWAETPGVAKSLPSFTKSLSGKLRTREEGADTIIWLA 300

Query: 301 LQPKEKLVPGAFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGLA 340
           LQP EKLVPGAFYFDRSEAPKHLAFAATKSSH  IGSIYDHLRSLSGLA
Sbjct: 301 LQPNEKLVPGAFYFDRSEAPKHLAFAATKSSHATIGSIYDHLRSLSGLA 349

BLAST of HG10022528 vs. ExPASy TrEMBL
Match: A0A6J1CR54 (dehydrogenase/reductase SDR family member 12 isoform X1 OS=Momordica charantia OX=3673 GN=LOC111013479 PE=4 SV=1)

HSP 1 Score: 592.4 bits (1526), Expect = 1.2e-165
Identity = 292/338 (86.39%), Postives = 316/338 (93.49%), Query Frame = 0

Query: 1   MEFGALQLRIHISIGALAMFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIE 60
           ME GAL +R++ISIGALAMFLL AWR +AFGVYG+L+FTKS +IEHS KFKPEDMQ  IE
Sbjct: 1   MERGALHIRVNISIGALAMFLLKAWRATAFGVYGFLHFTKSGFIEHSKKFKPEDMQTSIE 60

Query: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICD 120
           GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLE+CD
Sbjct: 61  GKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEVCD 120

Query: 121 LSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESV 180
           LSS+S+IKSF+S+  +K+VPVH+L+NNAGLLE NRI T EGFELNFAVNVLGTYAMTES+
Sbjct: 121 LSSVSEIKSFASNLTSKDVPVHILINNAGLLEHNRIMTPEGFELNFAVNVLGTYAMTESM 180

Query: 181 LPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEI 240
           +PLLEKAAPDAKVITVSSGGMYSVPLTNDLQFS++ FDGVKQY+LNKRVQVALTEKWAE+
Sbjct: 181 MPLLEKAAPDAKVITVSSGGMYSVPLTNDLQFSDDKFDGVKQYSLNKRVQVALTEKWAEM 240

Query: 241 YSNKGIGFYSMHPGWAETPGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPG 300
           YSNKGIGFYSMHPGWAETPGV KSLPSFSKSLSGKLRT EEGADT++WLALQPKEKL  G
Sbjct: 241 YSNKGIGFYSMHPGWAETPGVAKSLPSFSKSLSGKLRTREEGADTVVWLALQPKEKLASG 300

Query: 301 AFYFDRSEAPKHLAFAATKSSHTAIGSIYDHLRSLSGL 339
           AFYFDRSEAPKHLAFAAT SSH AIGSI D LRSLSGL
Sbjct: 301 AFYFDRSEAPKHLAFAATSSSHAAIGSIVDSLRSLSGL 338

BLAST of HG10022528 vs. TAIR 10
Match: AT4G09750.1 (NAD(P)-binding Rossmann-fold superfamily protein )

HSP 1 Score: 509.6 bits (1311), Expect = 1.9e-144
Identity = 243/320 (75.94%), Postives = 280/320 (87.50%), Query Frame = 0

Query: 19  MFLLNAWRRSAFGVYGYLNFTKSAYIEHSNKFKPEDMQMDIEGKNCIVTGANSGIGYATA 78
           MFLL  WR +AFGVYGY+NFTKS +++HS KFKPEDMQ+ IEGKNC+VTGANSGIG+A A
Sbjct: 1   MFLLKTWRSTAFGVYGYMNFTKSGFLDHSKKFKPEDMQLQIEGKNCVVTGANSGIGFAAA 60

Query: 79  EGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICDLSSISDIKSFSSDFITKN 138
           EGLASRGATVYMVCRNKERG+ ALS+I++ TGNQN++LE+CDLSS+++IKSF+S F +K+
Sbjct: 61  EGLASRGATVYMVCRNKERGQEALSKIQTSTGNQNVYLEVCDLSSVNEIKSFASSFASKD 120

Query: 139 VPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESVLPLLEKAAPDAKVITVSS 198
           VPVHVLVNNAGLLE  R TT EGFEL+FAVNVLGTY MTE +LPLLEKA PDAKVITV+S
Sbjct: 121 VPVHVLVNNAGLLENKRTTTPEGFELSFAVNVLGTYTMTELMLPLLEKATPDAKVITVAS 180

Query: 199 GGMYSVPLTNDLQFSEENFDGVKQYALNKRVQVALTEKWAEIYSNKGIGFYSMHPGWAET 258
           GGMY+ PLT DLQFS E FDGV+QYA NKR+QVALTEKWA+ Y NKGIGFYSMHPGWAET
Sbjct: 181 GGMYTSPLTTDLQFSGEKFDGVEQYARNKRIQVALTEKWADKYKNKGIGFYSMHPGWAET 240

Query: 259 PGVTKSLPSFSKSLSGKLRTSEEGADTIIWLALQPKEKLVPGAFYFDRSEAPKHLAFAAT 318
           PGV KSLPSFS+S +GKLRTSE+GADTI+WLALQPKEKLV GAFYFDR+EAPKHL  A T
Sbjct: 241 PGVAKSLPSFSESFAGKLRTSEQGADTIVWLALQPKEKLVSGAFYFDRAEAPKHLKLAGT 300

Query: 319 KSSHTAIGSIYDHLRSLSGL 339
             SH  I S+ D + S++ L
Sbjct: 301 SKSHDLIDSVIDSVHSMAAL 320

BLAST of HG10022528 vs. TAIR 10
Match: AT4G11410.1 (NAD(P)-binding Rossmann-fold superfamily protein )

HSP 1 Score: 110.5 bits (275), Expect = 2.6e-24
Identity = 78/263 (29.66%), Postives = 136/263 (51.71%), Query Frame = 0

Query: 57  MDIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHL 116
           +D  G   IVTGA+SGIG  T   LA RG  V M  RN + G     +I  +     I +
Sbjct: 25  IDGTGLTAIVTGASSGIGEETTRVLALRGVHVVMAVRNTDSGNQVRDKILKEIPQAKIDV 84

Query: 117 EICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAM 176
              DLSS++ ++SF+S++ + ++P+++L+NNAG++    + +S+  EL FA N LG + +
Sbjct: 85  MKLDLSSMASVRSFASEYQSLDLPLNLLINNAGIMACPFLLSSDNIELQFATNHLGHFLL 144

Query: 177 TESVLPLLEKAAPDA----KVITVSSGG---MYSVPLTNDLQFSEENFDGVKQYALNKRV 236
           T  +L  ++K A ++    +++ VSS G    Y   +  D    E  ++ ++ Y  +K  
Sbjct: 145 TNLLLERMKKTASESNREGRIVIVSSEGHRFAYREGVQFDKINDEARYNTLQAYGQSKLG 204

Query: 237 QVALTEKWAEIYSNKGIGF--YSMHPGWAETPGVT-KSLPSFSKSLSGK--LRTSEEGAD 296
            +    + A ++  +G+     S+HPG   T  +   S  +   +  GK  L++  +GA 
Sbjct: 205 NILHATELARLFKEQGVNITANSLHPGSIMTNLLRYHSFINTIGNAVGKYVLKSIPQGAA 264

Query: 297 TIIWLALQPKEKLVPGAFYFDRS 308
           T  + AL P+ K V G +  D +
Sbjct: 265 TTCYAALHPQAKGVSGEYLMDNN 287

BLAST of HG10022528 vs. TAIR 10
Match: AT4G24050.1 (NAD(P)-binding Rossmann-fold superfamily protein )

HSP 1 Score: 110.5 bits (275), Expect = 2.6e-24
Identity = 82/269 (30.48%), Postives = 133/269 (49.44%), Query Frame = 0

Query: 58  DIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLE 117
           D+     ++TGA SGIG  TA  LA RGA +    RN +  E A   I S+     I + 
Sbjct: 31  DLRSITAVITGATSGIGAETARVLAKRGARLIFPARNVKAAEEAKERIVSEFPETEIVVM 90

Query: 118 ICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMT 177
             DLSSI+ +++F +DF + ++P+++L+NNAG L      + +G E+ FA N LG + +T
Sbjct: 91  KLDLSSIASVRNFVADFESLDLPLNLLINNAGKLAHEHAISEDGIEMTFATNYLGHFLLT 150

Query: 178 ESVLPLL----EKAAPDAKVITVSSG--GMYSVPLTNDLQFSEE---NFDGVKQYALNKR 237
             +L  +    E+     +++ V+SG  G +S  L   L+   +    FD  + YAL+K 
Sbjct: 151 NLLLNKMIQTAEETGVQGRIVNVTSGIHGWFSGDLIEYLRLISQPKCQFDATRAYALSKL 210

Query: 238 VQVALTEKWAEIYSNKG--IGFYSMHPGWAET------PGVTKSLPSFSKSLSGKL-RTS 297
             V  T++ +      G  +    +HPG   T       G+   L  F   L+ KL +T 
Sbjct: 211 ANVLHTKELSSRLQKIGANVTVNCVHPGVVRTRLTRDREGLLTDLVFF---LASKLVKTV 270

Query: 298 EEGADTIIWLALQPKEKLVPGAFYFDRSE 309
            + A T  ++A  P+   V G ++ D +E
Sbjct: 271 PQAAATTCYVATNPRLVNVSGKYFTDCNE 296

BLAST of HG10022528 vs. TAIR 10
Match: AT5G50130.1 (NAD(P)-binding Rossmann-fold superfamily protein )

HSP 1 Score: 109.4 bits (272), Expect = 5.8e-24
Identity = 87/291 (29.90%), Postives = 144/291 (49.48%), Query Frame = 0

Query: 65  IVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLEICDLSSI 124
           I+TG  SGIG  TA  LA RG  V M  R+ ++ E     I  +    +I L   DLSS+
Sbjct: 40  IITGGTSGIGAETARVLAKRGVRVVMAVRDMKKAEMVKERIIRENPEADIILFEIDLSSL 99

Query: 125 SDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMTESVLPLL 184
           S +  F S F+++++P+++L+NNAG+   N   + E  EL FA N LG Y +TE ++  +
Sbjct: 100 SSVARFCSQFLSQDLPLNILINNAGVFSPNLEFSEEKIELTFATNFLGHYLLTEMLIEKM 159

Query: 185 ----EKAAPDAKVITVSS-------GGMYSVPLTNDLQFSEENFDGVKQYALNKRVQV-- 244
               EK+  + ++I +SS          +S P    L      ++G + YA +K   +  
Sbjct: 160 IDTAEKSGIEGRIINLSSVIHNWVKPDCFSFP---KLLHPISRYNGTRAYAQSKLATILH 219

Query: 245 --ALTEKWAEIYSNKGIGFYSMHPGWAETPGVTKSLPSFSKSL----SGKLRTSEEGADT 304
             AL+++  +   N  +   ++HPG  +T  +      F+ SL    S  L++  +GA T
Sbjct: 220 AKALSKQLKD--RNANVTINAVHPGIVKTGIIRAHKGLFTDSLFLIASKLLKSISQGAAT 279

Query: 305 IIWLALQPKEKLVPGAFYFDRSEAP-KHLA---FAATKSSHTAIGSIYDHL 333
             ++AL  + K + G ++ D +E     LA   + A K    +   I+DHL
Sbjct: 280 TCYVALSNETKGLSGKYFADCNETNCSDLANDEYVALKLCTQSRALIHDHL 325

BLAST of HG10022528 vs. TAIR 10
Match: AT1G64590.1 (NAD(P)-binding Rossmann-fold superfamily protein )

HSP 1 Score: 107.1 bits (266), Expect = 2.9e-23
Identity = 79/271 (29.15%), Postives = 135/271 (49.82%), Query Frame = 0

Query: 58  DIEGKNCIVTGANSGIGYATAEGLASRGATVYMVCRNKERGEAALSEIKSKTGNQNIHLE 117
           D+     I+TGA SGIG  TA  LA RGA + +  R+ +  E   + I S+  +  I + 
Sbjct: 31  DLRSLTAIITGATSGIGAETARVLAKRGARLVLPARSVKTAEETKARILSEFPDAEIIVM 90

Query: 118 ICDLSSISDIKSFSSDFITKNVPVHVLVNNAGLLEKNRITTSEGFELNFAVNVLGTYAMT 177
             DLSS++ ++ F  DF + N+P+++L+NNAG        + +G E+ FA N LG + +T
Sbjct: 91  HLDLSSLTSVRRFVDDFESLNLPLNILINNAGKYAHKHALSEDGVEMTFATNYLGHFLLT 150

Query: 178 ESVL-PLLEKAAP---DAKVITVS-------SGGMYSVPLTNDLQFSEENFDGVKQYALN 237
           + +L  ++E AA      +++ V+       SG M  +    D+  +  N+D  + YAL+
Sbjct: 151 KLLLKKMIETAAQTGVQGRIVNVTSVVHSWFSGDM--LQYLADISRNNRNYDATRAYALS 210

Query: 238 KRVQVALTEKWAEIY--SNKGIGFYSMHPGWAET------PGVTKSLPSFSKSLSGKLRT 297
           K   V  T + + +    +  +    +HPG  +T       GV   L  F    S  L++
Sbjct: 211 KLANVLHTVELSRLLHKMDANVTANCVHPGIVKTRLTRDREGVVTDLVFF--LTSKLLKS 270

Query: 298 SEEGADTIIWLALQPKEKLVPGAFYFDRSEA 310
             + A T  ++A  P+ + V G ++ D +EA
Sbjct: 271 VPQAAATTCYVATSPRLRNVCGKYFSDCNEA 297

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_038899726.19.5e-17892.94dehydrogenase/reductase SDR family member 12 [Benincasa hispida][more]
XP_008461902.12.4e-17391.18PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Cucumis melo... [more]
XP_004139691.14.6e-17290.29dehydrogenase/reductase SDR family member 12 [Cucumis sativus][more]
XP_023535216.11.3e-17189.71dehydrogenase/reductase SDR family member 12 isoform X2 [Cucurbita pepo subsp. p... [more]
KAG6592207.12.3e-17189.71Dehydrogenase/reductase SDR family member 12, partial [Cucurbita argyrosperma su... [more]
Match NameE-valueIdentityDescription
A6QP058.7e-6544.59Dehydrogenase/reductase SDR family member 12 OS=Bos taurus OX=9913 GN=DHRS12 PE=... [more]
A0PJE24.0e-6243.53Dehydrogenase/reductase SDR family member 12 OS=Homo sapiens OX=9606 GN=DHRS12 P... [more]
Q8TC122.2e-3131.36Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2[more]
Q9QYF14.8e-3131.47Retinol dehydrogenase 11 OS=Mus musculus OX=10090 GN=Rdh11 PE=1 SV=2[more]
Q96NR81.1e-3034.78Retinol dehydrogenase 12 OS=Homo sapiens OX=9606 GN=RDH12 PE=1 SV=3[more]
Match NameE-valueIdentityDescription
A0A1S4E3H21.2e-17391.18dehydrogenase/reductase SDR family member 12 isoform X1 OS=Cucumis melo OX=3656 ... [more]
A0A6J1F9921.4e-17189.71dehydrogenase/reductase SDR family member 12 OS=Cucurbita moschata OX=3662 GN=LO... [more]
A0A6J1IKU61.2e-17089.68dehydrogenase/reductase SDR family member 12 isoform X2 OS=Cucurbita maxima OX=3... [more]
A0A6J1INJ93.3e-16887.11dehydrogenase/reductase SDR family member 12 isoform X1 OS=Cucurbita maxima OX=3... [more]
A0A6J1CR541.2e-16586.39dehydrogenase/reductase SDR family member 12 isoform X1 OS=Momordica charantia O... [more]
Match NameE-valueIdentityDescription
AT4G09750.11.9e-14475.94NAD(P)-binding Rossmann-fold superfamily protein [more]
AT4G11410.12.6e-2429.66NAD(P)-binding Rossmann-fold superfamily protein [more]
AT4G24050.12.6e-2430.48NAD(P)-binding Rossmann-fold superfamily protein [more]
AT5G50130.15.8e-2429.90NAD(P)-binding Rossmann-fold superfamily protein [more]
AT1G64590.12.9e-2329.15NAD(P)-binding Rossmann-fold superfamily protein [more]
InterPro
Analysis Name: InterPro Annotations of Bottle gourd (Hangzhou Gourd) v1
Date Performed: 2022-08-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002347Short-chain dehydrogenase/reductase SDRPRINTSPR00081GDHRDHcoord: 272..292
score: 24.08
coord: 139..150
score: 45.85
coord: 244..261
score: 26.99
coord: 63..80
score: 44.25
coord: 223..242
score: 22.99
IPR002347Short-chain dehydrogenase/reductase SDRPFAMPF00106adh_shortcoord: 62..263
e-value: 1.6E-27
score: 96.3
NoneNo IPR availableGENE3D3.40.50.720coord: 47..332
e-value: 6.7E-60
score: 204.6
NoneNo IPR availablePANTHERPTHR24320:SF124NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEINcoord: 25..331
NoneNo IPR availablePANTHERPTHR24320RETINOL DEHYDROGENASEcoord: 25..331
IPR036291NAD(P)-binding domain superfamilySUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 55..306

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
HG10022528.1HG10022528.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0016491 oxidoreductase activity