HG10012189 (gene) Bottle gourd (Hangzhou Gourd) v1

Overview


Name	HG10012189
Type	gene
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	Phosphomevalonate kinase
Location	Chr01: 18539068 .. 18544110 (-)
RNA-Seq Expression	HG10012189
Synteny	HG10012189

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideCDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGCTGTGTAAGTCTGTTCGTTCTTTGCGTTGTTTATATTGATTGCCTCATTTACGATTGATCGATTCAGGAATGTGTTTGTTTGTGATTCATTGTTGTTAGTTTGATTTTGATCTCGGGAAAAGAAATTAATTAGACTGTTTAATTTTTAGTCATACTTCAGCTCTGAAATTCTAGTCGAGGATACTGAACTGCTTTCAGTATGACCTCTAAAATTCTAGTTGACTGTTTTTACATGCTTTTTGTGATCTTATTTTTGCTGCAATTTTATATGTGGCAGGGTTGCTTCAGCTCCAGGGAAAGTGTTAATTGCCGGAGGTTACCTTGTCTTGGAGAAACCGAATGCAGGGCTCGTACTTAGTACTAATGCTCGTTTTTATGCAATTGTAAAACCCACTTACGAGGAAATCAAGCCTGACAGTTGGGCATGGGTGCGTGGTTCTTTGATAATTTTTCCCTGTGAAACTTATTGTTTCTTAATCCTTTAAACTTCAGCTTTGTTAACGGTATTTTGGTTTGGTAGTTGCATGTTGTTGGTGATATGTTCTTTATTTTGTTGTTTGTTCATGATTAAGTTTTCTGCTGAGTGGAAATAGTACATTGAGAATTGGGATCAAAATAATTTCCTGCTAATCTGAGAATCAGAACCAAAATATTGGTAGTCACATACTTCTGGATTTATGGTGTTTTCAACTGGGGGAATATCACATTGCTTGAACAACTTGCTATTTATGACTAGTTATGAGCTGAACTCTATTGCTTAGATAAATTTGTTAGAATAGGAAATGGGATTCATTCATTTTATTATTATGTGTATTACTCCTGGATTCACTGTCTATATAATGCTAATATTCAAACGAACTCTTGAGAAAAAGTTCAATCAACATATGTCAAATACCTTTTTGCTTAATGGTCCATATTTTTCAGTCATGGACAGATGTTAAGTTGACATCTCCCCAGCTCCTGAGAGAGAGCATCTACAAATTGTCATTGAAAAACCAATCTCTTCAGAGTGTCTCTCCAAGGCAAGTAAATTAGTTATTCTAGTTGAGCATTGGAAATTCTGTTTATAAGCACATGTCCGTGCTGTTATGTAAATAAAACAAGCTAAATTTAGTTGTTTGTTTCATTTTACATTCCTAACCAGTGATCACCATCATACTTAAATTTTCAGTGTTTTAAATTAGTGTGGTTTTATCATATTATGGATGGGCTTTTCTATTTTCTGTATCTCTAGTTAATGAATTTCGATTTATCGAGATCAGGGTTATTAGCAAGATAGAGATAAAATGCTTCTCATTTCGTAATTAATGTTCACTTATATGTACTGCATACTGTTTCAGTCAATCAAGAAACCCTTTTGTAGAAAGAGCAGTGGAATATTGTGTAGCAGCTGCGTGTGCAAAATTTGTTGACAAGGACAATAAGGATGCACTACACAAACTGCTCTTGCAAGGTATGTTTAGTTTTTTGCCCATTCCCTAATCTTCATCTTGCAATAATCAAATTGCTTGTATATCCTGCTAACTCCATGATTCATTTGGACTGAACTTGCAGGTCTTGATATCACTATTGTAGGTTGCAATGAGTTCTACTCTTATCGGAGTCAGGTACTGTCCCATTGCTCATTAGTAGAATGCTTCATGCCCTTGCTCTCTCTCTCTCTGTCAGTACCCTTTTGGGGGGCACAATATTTGGGTGTTAACCTCTTTTTAATTGATTTTCTTGCTTTGTTATTTGGCTGTACTCTAGAACGATGTTTTTACAGTTTATGCAATGTCTTTTTCATAGATTGAGGCTCGTGGACTCCCACTAACATCAGAATCATTGGCTTCCTTGCCTCCTTTTTCATCAATTACATTCAATGATGAGGAATCACATGGGAAAAATTGCAAGCCTGAAGTTGCAAAAACTGGATTGGGCTCATCTGCTGCAATGACAGCTGCTGTAGTTGCTGCTTTACTTAACTACCTAGGGGTTGTAAATCTTTCCTTATTGACAGGTGACCAAGAACAGAGAGGCAGTGCGGATCTTGATTTGGTGCATATAATAGCTCAAAGTGCCCACTGCATTGCACAGGGAAAAGTTGGCAGCGGCTTTGATGTCAGTTCTGCAGTTTATGGCAGTCAACGTTATGTTCGGTTTTCACCAGAAGTGCTTTCTTCTGCTCAGGTCTCTTCTTCATGGGCTATCCCTCTTTATGTGTTGTTTGGTCAGAGTGCATTCTGAACTTAAATAAAATGGTTTCATCACTTTTGGTGCATATTTCCTTGTAATATGAGAAGGTTGTTTGGTTTCCTACCTGTAGATTTATATTATTTAAAATATTTTTTGTTTAGATTAGATACATTTCTAATTTGATTTTACATTTATTAGTTAATATCTTTTGCTCATTTTAAGTTAGTTTCCTTTTCTGTAATTTCCTGTTTATTCTTTATGTAATTTGGTTATTCAGTGAATACAATTTCTCCCAAAAACTTCACTACCTAATGAAGACCTTTACTGATTTTTTTCACAGTAGGTTTGTTTTACTTTGGTTTTGACCGCATAGGAAGCTGATGGAAGTCCGAAGTATAGTGAGTCAGTGACTTTATAATTGTTGGTTGTTGGATGTATAATCCTTCTAGAGAACTCCTAGGGGACATTCCTCTGCTCTGGGGAAGTAAAATAGCAACTGAATTTTTGGGCATTACACTGTTTCTGACTGTCTGTAACCCCAATCATTTCATATACCTACCATTCGTCGGATTAAATTGCAAGTTGTGCCAATTTTATTATATCTATGAGACTTATATTAGCTATGTTCAAGATGTGACTAACAAACTCAATTACGTATTTGACCTTTAATCACTGAGTCTGATAATAATAAATTGTGTAAAGTAGGCTTCATACTGCACCCCTGTCGAGAATCTTATTTTTATTTTCCGATTAAAACTTCCATTACTTTCTGTTGCCTTATTGTCTATATGCAACCATGCAGGCTGCCAAGAATGGAATGCCCATAGAAGAGGTCATTGTTGATATCTTAAATCAGAAGTGGGACCATGAGAGGACTAAGTTCTCTTTGCCTCCATTAATGACTCTTGTAAGCTGCCGAAATCTGCCTGTTAAAAATAATTTTGGAAGGCATTTTTATATTACCACTTCAAAAAGTTGTACGTTTAGAAGTTAGTTTGTGTGCTAAAGAAATGAGGCTCTATTAGTGAAGACTGGTTTGAAGATTTTGTGATTTTCCCACTTAATCTAATATTATGAGACTCATACTTTCTTATCATACACTTTCTGGAGGGTTACGAGCACTTGTAATTATTTAATCGTAATTCAACTCTGCATGCTCCACACATGTTGCAAAATTCAGCTTTACTTGTTCCACAGGAATCTGAATTTCACCTTATTGTCACTTGATCTTGTCATCACAGGAACTCGTGTTTTGTAAGCCAATCAATTTTGATTTGTGATGTTCAGTACAGCTTGTTTTTCTGGTCTGCCTCTGTTGAATCACTATAATAGACAAACTTTGTCAATAGATTATAATCTTTTCCTCTACCATCACTTTATTTTGTAAATTTCTGGAAGTCATTAAGCTCGGTGATTTAGTAAACTTCATTTCACAACAACACGACACCCATGCTTCTCAGTTTTTGAAGTGAGTTCTCTCTCTTAACAAGTACGACAGATTTGGAGTGCATCTTGAATATATGTGTATGTGTGGATATATATATATATTATTTGTTATTTAATTTTGCTTTGCTAACAATTAGGAAATGTTGGGGGCAGTAGAAATTTGAAATTCCAAATTGTGTCCTCTCTTGGTCTTTGTACTTAAATAATATGCATTTGTATGACCTTGTATATTCTTTCACGTTCTTCAATGAAAGCTCAGTTTCTTATGCAATTGTTACTTCTGCATATACTTTTTCTTTTTTGTCCATCATCATGGTGCTTTGAACAGGTACTTGGGGAGCCAGGAGTGGGAGGATCATCCACGCCTTCAATGGTAGGTGCTGTCAAAAAATGGCAAAAATCTGACTCTCAAAGGTCCCTAGACACGTGGAGGAAGTTGTCAGAAGGGAATTCAGAACTTGAAACTCAACTCAATACGTTGAGTAAACTTGCAGCTGAACACTGGGATGCTTATAAATATATCATAAACGGTTGTTGCAAGCTGACCTCGGAGAAGGTATTTCTCTTACCTTTATAATCTAAATCTATCATTGAAGACTGAGGTAATAGCCTTTTTTGTGAAAAATAAAAAAAAAAAAAATACTACTATAATTGATCACTAATCGTGAAAGTTTTACATAATATGAGAGGTGGACCAGAAGTCTAAAATACCACATATACACAAAATATATTGTAGACCCAAAATTTGTATCTGACTTGGTCTTTGGCTTTTAGTCAGGATGCTATTACTTTCAACTTAGAGTACGTTAGCAAATTGTGTCTCTTTCCATATATATCTATCTGCATTAATGTTGAAGCAATTTAAAAAAAAAATCTGGCAGTGGATTCTTCAAGCCACAGAACCAAGCCAGCAAGCCATCATCAAAGCATTATTAGGAGCAAGAAATGCTATGCTTCAGATCAGGCATCATATGCGCTTAATGGGTGAAGCTGCTGGTGTTCCGGTTAGTTTTTCCTTCTTTAATTACTTTGTTCCCTTGTTATATTAACTAGCATTTTGTCTGCACAAGTACGTGTGTAGATAATTGTCAGGACATGGTGACGGTGACAAATACACGTATAGATAACTGAACTCCATTTTCTGGGATTTGTAGATTGAGCCAGATTCACAAACCAAGCTTTTAGATGCTACCATGAATATGGAAGGAGTACTGTTAGCCGGTGTTCCAGGGGCAGGTGGATTTGATGCTGTTTTTGCTGTGACCTTGGGAGACTCAACCAGCAATGTGATTAAATCATGGAGTTCACTGGATATTTTGGCTCTCCTTGTTAGAGAAGATCCCCGTGGTGTTGCTTTGGAAACTTGTGATCCACGAACCAAGGCAATTACATCAGCTGTTTCATCACTTCATATTTAG

mRNA sequence

ATGGCTGTGGTTGCTTCAGCTCCAGGGAAAGTGTTAATTGCCGGAGGTTACCTTGTCTTGGAGAAACCGAATGCAGGGCTCGTACTTAGTACTAATGCTCGTTTTTATGCAATTGTAAAACCCACTTACGAGGAAATCAAGCCTGACAGTTGGGCATGGTCATGGACAGATGTTAAGTTGACATCTCCCCAGCTCCTGAGAGAGAGCATCTACAAATTGTCATTGAAAAACCAATCTCTTCAGAGTGTCTCTCCAAGGCAAGTAAATTATCAATCAAGAAACCCTTTTGTAGAAAGAGCAGTGGAATATTGTGTAGCAGCTGCGTGTGCAAAATTTGTTGACAAGGACAATAAGGATGCACTACACAAACTGCTCTTGCAAGGTCTTGATATCACTATTGTAGGTTGCAATGAGTTCTACTCTTATCGGAGTCAGATTGAGGCTCGTGGACTCCCACTAACATCAGAATCATTGGCTTCCTTGCCTCCTTTTTCATCAATTACATTCAATGATGAGGAATCACATGGGAAAAATTGCAAGCCTGAAGTTGCAAAAACTGGATTGGGCTCATCTGCTGCAATGACAGCTGCTGTAGTTGCTGCTTTACTTAACTACCTAGGGGTTGTAAATCTTTCCTTATTGACAGGTGACCAAGAACAGAGAGGCAGTGCGGATCTTGATTTGGTGCATATAATAGCTCAAAGTGCCCACTGCATTGCACAGGGAAAAGTTGGCAGCGGCTTTGATGTCAGTTCTGCAGTTTATGGCAGTCAACGTTATGTTCGGTTTTCACCAGAAGTGCTTTCTTCTGCTCAGGCTGCCAAGAATGGAATGCCCATAGAAGAGGTCATTGTTGATATCTTAAATCAGAAGTGGGACCATGAGAGGACTAAGTTCTCTTTGCCTCCATTAATGACTCTTGTACTTGGGGAGCCAGGAGTGGGAGGATCATCCACGCCTTCAATGGTAGGTGCTGTCAAAAAATGGCAAAAATCTGACTCTCAAAGGTCCCTAGACACGTGGAGGAAGTTGTCAGAAGGGAATTCAGAACTTGAAACTCAACTCAATACGTTGAGTAAACTTGCAGCTGAACACTGGGATGCTTATAAATATATCATAAACGGTTGTTGCAAGCTGACCTCGGAGAAGTGGATTCTTCAAGCCACAGAACCAAGCCAGCAAGCCATCATCAAAGCATTATTAGGAGCAAGAAATGCTATGCTTCAGATCAGGCATCATATGCGCTTAATGGGTGAAGCTGCTGGTGTTCCGATTGAGCCAGATTCACAAACCAAGCTTTTAGATGCTACCATGAATATGGAAGGAGTACTGTTAGCCGGTGTTCCAGGGGCAGGTGGATTTGATGCTGTTTTTGCTGTGACCTTGGGAGACTCAACCAGCAATGTGATTAAATCATGGAGTTCACTGGATATTTTGGCTCTCCTTGTTAGAGAAGATCCCCGTGGTGTTGCTTTGGAAACTTGTGATCCACGAACCAAGGCAATTACATCAGCTGTTTCATCACTTCATATTTAG

Coding sequence (CDS)

ATGGCTGTGGTTGCTTCAGCTCCAGGGAAAGTGTTAATTGCCGGAGGTTACCTTGTCTTGGAGAAACCGAATGCAGGGCTCGTACTTAGTACTAATGCTCGTTTTTATGCAATTGTAAAACCCACTTACGAGGAAATCAAGCCTGACAGTTGGGCATGGTCATGGACAGATGTTAAGTTGACATCTCCCCAGCTCCTGAGAGAGAGCATCTACAAATTGTCATTGAAAAACCAATCTCTTCAGAGTGTCTCTCCAAGGCAAGTAAATTATCAATCAAGAAACCCTTTTGTAGAAAGAGCAGTGGAATATTGTGTAGCAGCTGCGTGTGCAAAATTTGTTGACAAGGACAATAAGGATGCACTACACAAACTGCTCTTGCAAGGTCTTGATATCACTATTGTAGGTTGCAATGAGTTCTACTCTTATCGGAGTCAGATTGAGGCTCGTGGACTCCCACTAACATCAGAATCATTGGCTTCCTTGCCTCCTTTTTCATCAATTACATTCAATGATGAGGAATCACATGGGAAAAATTGCAAGCCTGAAGTTGCAAAAACTGGATTGGGCTCATCTGCTGCAATGACAGCTGCTGTAGTTGCTGCTTTACTTAACTACCTAGGGGTTGTAAATCTTTCCTTATTGACAGGTGACCAAGAACAGAGAGGCAGTGCGGATCTTGATTTGGTGCATATAATAGCTCAAAGTGCCCACTGCATTGCACAGGGAAAAGTTGGCAGCGGCTTTGATGTCAGTTCTGCAGTTTATGGCAGTCAACGTTATGTTCGGTTTTCACCAGAAGTGCTTTCTTCTGCTCAGGCTGCCAAGAATGGAATGCCCATAGAAGAGGTCATTGTTGATATCTTAAATCAGAAGTGGGACCATGAGAGGACTAAGTTCTCTTTGCCTCCATTAATGACTCTTGTACTTGGGGAGCCAGGAGTGGGAGGATCATCCACGCCTTCAATGGTAGGTGCTGTCAAAAAATGGCAAAAATCTGACTCTCAAAGGTCCCTAGACACGTGGAGGAAGTTGTCAGAAGGGAATTCAGAACTTGAAACTCAACTCAATACGTTGAGTAAACTTGCAGCTGAACACTGGGATGCTTATAAATATATCATAAACGGTTGTTGCAAGCTGACCTCGGAGAAGTGGATTCTTCAAGCCACAGAACCAAGCCAGCAAGCCATCATCAAAGCATTATTAGGAGCAAGAAATGCTATGCTTCAGATCAGGCATCATATGCGCTTAATGGGTGAAGCTGCTGGTGTTCCGATTGAGCCAGATTCACAAACCAAGCTTTTAGATGCTACCATGAATATGGAAGGAGTACTGTTAGCCGGTGTTCCAGGGGCAGGTGGATTTGATGCTGTTTTTGCTGTGACCTTGGGAGACTCAACCAGCAATGTGATTAAATCATGGAGTTCACTGGATATTTTGGCTCTCCTTGTTAGAGAAGATCCCCGTGGTGTTGCTTTGGAAACTTGTGATCCACGAACCAAGGCAATTACATCAGCTGTTTCATCACTTCATATTTAG

Protein sequence

MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKLTSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDALHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSKLAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILALLVREDPRGVALETCDPRTKAITSAVSSLHI

Homology

[Close]

BLAST of HG10012189 vs. NCBI nr
Match: XP_038887930.1 (phosphomevalonate kinase, peroxisomal [Benincasa hispida])

HSP 1 Score: 946.4 bits (2445), Expect = 1.0e-271
Identity = 483/511 (94.52%), Postives = 495/511 (96.87%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEEIKPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLKNQSLQSVSP     QSRNPFVERAVEYCVAAACAKFVDKDN+DA
Sbjct: 61  TSPQLLRESIYKLSLKNQSLQSVSPS----QSRNPFVERAVEYCVAAACAKFVDKDNEDA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES+GK+CK
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGKDCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           P+VAKTGLGSSAAMTAAVVAALLNYLGVVNLSL TGDQEQRGSADLDLVHIIAQSAHCIA
Sbjct: 181 PDVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLSTGDQEQRGSADLDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PIEEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGLPIEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD QRSL+TWR+LSEGNSELE QLNTLSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQRSLETWRQLSEGNSELENQLNTLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LA+EHWDAYKYIIN CCKLTSEKWI QATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA
Sbjct: 361 LASEHWDAYKYIINHCCKLTSEKWIYQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLD TMNMEGVLLAGVPGAGGFDAVFAVTLGDS SNV KSWSSLDIL 
Sbjct: 421 AGVPIEPDSQTKLLDTTMNMEGVLLAGVPGAGGFDAVFAVTLGDSISNVTKSWSSLDILT 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRTKAITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTKAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. NCBI nr
Match: XP_008466028.1 (PREDICTED: phosphomevalonate kinase [Cucumis melo] >KAA0038599.1 phosphomevalonate kinase [Cucumis melo var. makuwa] >TYK31198.1 phosphomevalonate kinase [Cucumis melo var. makuwa])

HSP 1 Score: 946.0 bits (2444), Expect = 1.3e-271
Identity = 486/511 (95.11%), Postives = 497/511 (97.26%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP Y+EIKPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPIYDEIKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLKNQSLQSVSP     QSRNPFVERAVEYCVAAA AKFVDKDNK+A
Sbjct: 61  TSPQLLRESIYKLSLKNQSLQSVSPS----QSRNPFVERAVEYCVAAASAKFVDKDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LH+LLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCK
Sbjct: 121 LHRLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESLGKNCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLN+LGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNFLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PIEEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPIEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD QRSLDTW+KLSEGNSELETQLNTLSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQRSLDTWKKLSEGNSELETQLNTLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWDAYKYIIN CCKLTSEKWI QATEP+QQAIIKALLGARNAMLQIRHHMRLMGEA
Sbjct: 361 LAAEHWDAYKYIINSCCKLTSEKWIHQATEPNQQAIIKALLGARNAMLQIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+ DPRT AITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESGDPRTNAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. NCBI nr
Match: XP_004136210.1 (phosphomevalonate kinase, peroxisomal [Cucumis sativus] >KAE8651424.1 hypothetical protein Csa_001745 [Cucumis sativus])

HSP 1 Score: 944.1 bits (2439), Expect = 5.0e-271
Identity = 484/511 (94.72%), Postives = 494/511 (96.67%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEEIKPDSWAWSWTD+KL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEIKPDSWAWSWTDIKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLKNQSL+SVSP     QSRNPFVERAVEYCVAAA AKFVDKDNK+A
Sbjct: 61  TSPQLLRESIYKLSLKNQSLESVSPS----QSRNPFVERAVEYCVAAASAKFVDKDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCK
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESLGKNCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSA LDLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSAGLDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PIEEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPIEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD Q+SLDTWRKLSEGNSELETQLNTL K
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSEGNSELETQLNTLHK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWDAYKYIIN CCKLTSEKWI QATEPSQQAIIKALLGARNAMLQIRHHMR MGEA
Sbjct: 361 LAAEHWDAYKYIINSCCKLTSEKWIHQATEPSQQAIIKALLGARNAMLQIRHHMRSMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNV KSWSSLDILA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVTKSWSSLDILA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRT AIT+AVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTNAITAAVSSVHI 507

[Close]

BLAST of HG10012189 vs. NCBI nr
Match: XP_023554025.1 (phosphomevalonate kinase, peroxisomal-like [Cucurbita pepo subsp. pepo])

HSP 1 Score: 921.4 bits (2380), Expect = 3.4e-264
Identity = 469/511 (91.78%), Postives = 491/511 (96.09%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEEIKP SWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLVTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEIKPGSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLK QSLQSVSP     Q+RNPFVE+AVEYCVAAACAKFVD DN++A
Sbjct: 61  TSPQLLRESIYKLSLKTQSLQSVSPS----QARNPFVEKAVEYCVAAACAKFVDNDNRNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES+G+N K
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGENRK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTG+QEQ+GSAD+DLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGEQEQKGSADVDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+P+EEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPVEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD Q+SLDTWRKLS+GNSELETQLN LSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSQGNSELETQLNMLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWD+YKYIIN C  LTSE+WI QA+EPSQQ IIKALLGARNAML+IRHHMRLMGEA
Sbjct: 361 LAAEHWDSYKYIINRCSMLTSEQWIHQASEPSQQTIIKALLGARNAMLEIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDST+NVIKSWS LD LA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTNNVIKSWSKLDTLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRTKAITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTKAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. NCBI nr
Match: XP_022963972.1 (phosphomevalonate kinase, peroxisomal-like [Cucurbita moschata] >XP_022963974.1 phosphomevalonate kinase, peroxisomal-like [Cucurbita moschata])

HSP 1 Score: 921.4 bits (2380), Expect = 3.4e-264
Identity = 469/511 (91.78%), Postives = 491/511 (96.09%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEEIKP SWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLVTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEIKPGSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLK QSLQSVSP     Q+RNPFVE+AVEYCVAAACAKFVD DNK+A
Sbjct: 61  TSPQLLRESIYKLSLKTQSLQSVSPS----QARNPFVEKAVEYCVAAACAKFVDNDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES+G+N K
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGENRK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTG+QEQ+GSAD+DLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGEQEQKGSADVDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+P++EVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPVQEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD Q+SLDTWRKLS+GNSELETQLN LSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSQGNSELETQLNMLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWD+YKYIIN C  LTSE+WI QA+EPSQQ IIKALLGARNAML+IRHHMRLMGEA
Sbjct: 361 LAAEHWDSYKYIINRCSMLTSEQWIHQASEPSQQTIIKALLGARNAMLEIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDST+NVIKSWS LD LA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTNNVIKSWSKLDTLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRTKAITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTKAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. ExPASy Swiss-Prot
Match: Q9C6T1 (Phosphomevalonate kinase, peroxisomal OS=Arabidopsis thaliana OX=3702 GN=PMK PE=1 SV=1)

HSP 1 Score: 690.6 bits (1781), Expect = 1.3e-197
Identity = 357/511 (69.86%), Postives = 420/511 (82.19%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP  EE+KP+SWAW WTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQL RES+YKLSL + +LQSVS       SRNPFVE A++Y +AA  A    + +K++
Sbjct: 61  TSPQLSRESMYKLSLNHLTLQSVSAS----DSRNPFVEHAIQYAIAA--AHLATEKDKES 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+G N+FYSYR+QIE+ GLPLT ESL +L PF+SITFN  ES+G N K
Sbjct: 121 LHKLLLQGLDITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMT AVVAALL+YLGVV+LS     + + G +DLD++H+IAQ++HC+A
Sbjct: 181 PEVAKTGLGSSAAMTTAVVAALLHYLGVVDLS-DPCKEGKFGCSDLDVIHMIAQTSHCLA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVS AVYGSQRYVRFSPEVLS AQ A  G+P+ EVI  IL  KWD++RT+FS
Sbjct: 241 QGKVGSGFDVSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLM L LGEPG GGSSTPSMVGAVKKWQ SD +++ + W+ LS+ N ELET+LN LSK
Sbjct: 301 LPPLMNLFLGEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LA +HWD Y  +I  C  LTSEKW+L ATEP  +AIIK LL AR AML+IR  MR MGEA
Sbjct: 361 LAKDHWDVYLRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           A VPIEP+SQT+LLD+TM+ EGVLLAGVPGAGGFDA+FA+TLGDS + + ++WSS ++LA
Sbjct: 421 ASVPIEPESQTQLLDSTMSAEGVLLAGVPGAGGFDAIFAITLGDSGTKLTQAWSSHNVLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDP GV LE+ DPRT  ITS VSS+H+
Sbjct: 481 LLVREDPHGVCLESGDPRTTCITSGVSSIHL 504

[Close]

BLAST of HG10012189 vs. ExPASy Swiss-Prot
Match: Q9UT88 (Probable phosphomevalonate kinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=erg8 PE=3 SV=1)

HSP 1 Score: 164.9 bits (416), Expect = 2.5e-39
Identity = 157/504 (31.15%), Postives = 235/504 (46.63%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           M V  SAPGKVLIAGGY+VL+   +GLV+   A+ YA      ++            V++
Sbjct: 1   MKVTCSAPGKVLIAGGYIVLDPQYSGLVIGLTAKGYASTTTLDDKC---------GTVRV 60

Query: 61  TSPQLLR-ESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKD 120
            SPQ +  E +Y +        +VSP +V+    N  +E+     V  A    ++     
Sbjct: 61  KSPQFINAEWLYNID------WTVSPIRVHQIYENCELEKNPNPFVQLALFYVINYFFST 120

Query: 121 ALHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNC 180
               L  Q L +T+   N +Y           P       S P F+ +          NC
Sbjct: 121 GRQPLCWQDLQVTLQVDNAYYHQ---------PQLKPDQTSYPKFNFL----------NC 180

Query: 181 K-PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQR-GSADLDLVHIIAQSAH 240
              +V KTGLGSSAAM  +++ +L  +L +  L+  TGD+  +   +   +VH +AQ AH
Sbjct: 181 TLGQVHKTGLGSSAAMITSLIGSL--FLSLRRLTDDTGDKSLKIDDSTKVIVHNLAQIAH 240

Query: 241 CIAQGKVGSGFDVSSAVYGSQRYVRFSPEVLSSA-----QAAKNGMPIEEVIVDILNQKW 300
           C AQGKVGSGFDV +A +GS  Y RF P+++        +  KN +     +  I+++KW
Sbjct: 241 CSAQGKVGSGFDVGAATWGSCIYRRFDPKLIEQLLVPYDEQIKN-INFSTELRKIVSKKW 300

Query: 301 DHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELE 360
             +   F LP    L++G+   GGSSTP MV  V++WQK + + S + +           
Sbjct: 301 S-DVVPFQLPATYCLLMGDV-AGGSSTPGMVKKVQQWQKENPEESKNCFD---------- 360

Query: 361 TQLNTLSKLAAEHWDAYKYIIN-GCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIR 420
                         D Y  +++   C L+SE   L +   SQ   I+ +L          
Sbjct: 361 --------------DLYSRVLSIKNCFLSSES--LDSELQSQFRSIRRIL---------- 420

Query: 421 HHMRLMGEAAGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLG--DSTSNV 480
              R+  EA  V IEP  QT +LD    + GV+  GVPGAGGFDA F + +   +   NV
Sbjct: 421 --QRITVEAK-VDIEPLKQTNILDNIEQLPGVIGVGVPGAGGFDAQFCLAINHTEIIENV 426

Query: 481 IKSWSSLDILALLVREDPRGVALE 494
           IK+W    ++ + V     G+A+E
Sbjct: 481 IKTWKDDGVVPMDVSPAFDGLAVE 426

[Close]

BLAST of HG10012189 vs. ExPASy Swiss-Prot
Match: P24521 (Phosphomevalonate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=ERG8 PE=1 SV=2)

HSP 1 Score: 154.8 bits (390), Expect = 2.6e-36
Identity = 140/469 (29.85%), Postives = 208/469 (44.35%), Query Frame = 0


Query: 6   SAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKLTSPQL 65
           SAPGK L+AGGYLVL+      V+  +AR +A+  P       D +     +V++ S Q 
Sbjct: 8   SAPGKALLAGGYLVLDTKYEAFVVGLSARMHAVAHPYGSLQGSDKF-----EVRVKSKQF 67

Query: 66  L-RESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDALHKL 125
              E +Y +S K+  +    P  +   S+NPF+E+ +    +       D  N++     
Sbjct: 68  KDGEWLYHISPKSGFI----PVSIG-GSKNPFIEKVIANVFSYFKPNMDDYCNRNL---- 127

Query: 126 LLQGLDITIVGCNEFYSYRSQI-EARGLPLTSESLASLPPFSSITFNDEESHGKNCKPEV 185
                 I I   + ++S    + E RG                   N   S   +   EV
Sbjct: 128 ----FVIDIFSDDAYHSQEDSVTEHRG-------------------NRRLSFHSHRIEEV 187

Query: 186 AKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIAQGK 245
            KTGLGSSA +   +  AL         S    D E       +++H +AQ AHC AQGK
Sbjct: 188 PKTGLGSSAGLVTVLTTAL--------ASFFVSDLENNVDKYREVIHNLAQVAHCQAQGK 247

Query: 246 VGSGFDVSSAVYGSQRYVRFSPEVLSSAQ---AAKNGMPIEEVIVDILNQKWDHERTKFS 305
           +GSGFDV++A YGS RY RF P ++S+     +A  G  +  ++ +   + W+       
Sbjct: 248 IGSGFDVAAAAYGSIRYRRFPPALISNLPDIGSATYGSKLAHLVDE---EDWNITIKSNH 307

Query: 306 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 365
           LP  +TL +G+    GS T  +V  VK W  S    SL  + +L   NS     L+ L +
Sbjct: 308 LPSGLTLWMGDI-KNGSETVKLVQKVKNWYDSHMPESLKIYTELDHANSRFMDGLSKLDR 367

Query: 366 LAAEHWDAYKYII-----NGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMR 425
           L   H D    I      N C   T +K+               +   R+A+  IR   R
Sbjct: 368 LHETHDDYSDQIFESLERNDC---TCQKY-------------PEITEVRDAVATIRRSFR 411

Query: 426 LMGEAAGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGD 465
            + + +G  IEP  QT LLD    ++GVL   +PGAGG+DA+  +T  D
Sbjct: 428 KITKESGADIEPPVQTSLLDDCQTLKGVLTCLIPGAGGYDAIAVITKQD 411

[Close]

BLAST of HG10012189 vs. ExPASy Swiss-Prot
Match: Q97UL6 (Phosphomevalonate kinase OS=Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) OX=273057 GN=SSO2988 PE=1 SV=1)

HSP 1 Score: 60.8 bits (146), Expect = 5.0e-08
Identity = 90/343 (26.24%), Postives = 141/343 (41.11%), Query Frame = 0


Query: 156 ESLASLPPFSSI-TFNDEE--SHGKNCKPEVAKTGLGSSAAMTAAVVAALLNYLGVVNLS 215
           E L+ LP    I  +ND+E    GK       KTGLGSS+A T ++ A L  Y  +    
Sbjct: 72  ERLSQLPQGYEIDLYNDKEFIIDGK-------KTGLGSSSAATVSLTACL--YYAI---- 131

Query: 216 LLTGDQEQRGSADLDLVHIIAQSAHCIAQGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQ 275
                    G  DL  +H +AQ A+   Q  +GSGFD++SAV+GS  Y RF+        
Sbjct: 132 --------HGKLDLFEIHKLAQIANYKRQKGIGSGFDIASAVFGSIVYKRFT-------- 191

Query: 276 AAKNGMPIEEVIVDILNQKWDHERTKFSLPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKS 335
                        D+    +  E+       +M       G  G S+ + VG V+K+ + 
Sbjct: 192 -------------DLDKMDFYFEKLNLGNYDMML------GFTGKSSET-VGLVRKFVEK 251

Query: 336 DSQRSLDTWRKLSEGNSELETQLNTLSKLAAEHWDAYKYIINGCCKLTSEKWILQATEPS 395
            +        +L +  + +  +L  L+KL                               
Sbjct: 252 SNLDDFKEIMRLIDEENYMAIKLIKLNKL------------------------------- 311

Query: 396 QQAIIKALLGARNAMLQIRHHMRLMGE-AAGVPIEPDSQTKLLDATMNMEGVLLAGVPGA 455
            +A+    LG        R ++  + E   GV +    + +L+      EG L+A  PGA
Sbjct: 312 DEAVEHIKLG--------RKYLNYIAERIVGVKLVSKMEEELIKIA-EEEGALVALSPGA 322

Query: 456 GGFDAVFAVTLGDSTSNVIKSWSSLDILALLVREDPRGVALET 495
           GG D++FA  LG+  + V ++WS   I  + V+ED  G+ LE+
Sbjct: 372 GGGDSIFA--LGNDLNRVREAWSKRGIFIIDVKED-EGLRLES 322

[Close]

BLAST of HG10012189 vs. ExPASy TrEMBL
Match: A0A5D3E5W3 (Phosphomevalonate kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold455G004830 PE=4 SV=1)

HSP 1 Score: 946.0 bits (2444), Expect = 6.3e-272
Identity = 486/511 (95.11%), Postives = 497/511 (97.26%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP Y+EIKPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPIYDEIKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLKNQSLQSVSP     QSRNPFVERAVEYCVAAA AKFVDKDNK+A
Sbjct: 61  TSPQLLRESIYKLSLKNQSLQSVSPS----QSRNPFVERAVEYCVAAASAKFVDKDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LH+LLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCK
Sbjct: 121 LHRLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESLGKNCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLN+LGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNFLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PIEEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPIEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD QRSLDTW+KLSEGNSELETQLNTLSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQRSLDTWKKLSEGNSELETQLNTLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWDAYKYIIN CCKLTSEKWI QATEP+QQAIIKALLGARNAMLQIRHHMRLMGEA
Sbjct: 361 LAAEHWDAYKYIINSCCKLTSEKWIHQATEPNQQAIIKALLGARNAMLQIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+ DPRT AITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESGDPRTNAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. ExPASy TrEMBL
Match: A0A1S3CQ96 (Phosphomevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103503581 PE=4 SV=1)

HSP 1 Score: 946.0 bits (2444), Expect = 6.3e-272
Identity = 486/511 (95.11%), Postives = 497/511 (97.26%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP Y+EIKPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPIYDEIKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLKNQSLQSVSP     QSRNPFVERAVEYCVAAA AKFVDKDNK+A
Sbjct: 61  TSPQLLRESIYKLSLKNQSLQSVSPS----QSRNPFVERAVEYCVAAASAKFVDKDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LH+LLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES GKNCK
Sbjct: 121 LHRLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESLGKNCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLN+LGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNFLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PIEEVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPIEEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD QRSLDTW+KLSEGNSELETQLNTLSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQRSLDTWKKLSEGNSELETQLNTLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWDAYKYIIN CCKLTSEKWI QATEP+QQAIIKALLGARNAMLQIRHHMRLMGEA
Sbjct: 361 LAAEHWDAYKYIINSCCKLTSEKWIHQATEPNQQAIIKALLGARNAMLQIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+ DPRT AITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESGDPRTNAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. ExPASy TrEMBL
Match: A0A6J1HGL2 (Phosphomevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111464112 PE=4 SV=1)

HSP 1 Score: 921.4 bits (2380), Expect = 1.7e-264
Identity = 469/511 (91.78%), Postives = 491/511 (96.09%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEEIKP SWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLVTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEIKPGSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLK QSLQSVSP     Q+RNPFVE+AVEYCVAAACAKFVD DNK+A
Sbjct: 61  TSPQLLRESIYKLSLKTQSLQSVSPS----QARNPFVEKAVEYCVAAACAKFVDNDNKNA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES+G+N K
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGENRK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTG+QEQ+GSAD+DLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGEQEQKGSADVDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+P++EVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPVQEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD Q+SLDTWRKLS+GNSELETQLN LSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSQGNSELETQLNMLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWD+YKYIIN C  LTSE+WI QA+EPSQQ IIKALLGARNAML+IRHHMRLMGEA
Sbjct: 361 LAAEHWDSYKYIINRCSMLTSEQWIHQASEPSQQTIIKALLGARNAMLEIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDST+NVIKSWS LD LA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTNNVIKSWSKLDTLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRTKAITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTKAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. ExPASy TrEMBL
Match: A0A6J1HTW0 (Phosphomevalonate kinase OS=Cucurbita maxima OX=3661 GN=LOC111466832 PE=4 SV=1)

HSP 1 Score: 918.7 bits (2373), Expect = 1.1e-263
Identity = 468/511 (91.59%), Postives = 490/511 (95.89%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP YEE+KPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLVTGGYLVLEKPNAGLVLSTNARFYAIVKPIYEEMKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRESIYKLSLK QSLQSVSP     Q+RNPFVE+AVEYCVAAACAKFVD DNK A
Sbjct: 61  TSPQLLRESIYKLSLKTQSLQSVSPS----QARNPFVEKAVEYCVAAACAKFVDNDNKKA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+GCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEES+G+N K
Sbjct: 121 LHKLLLQGLDITILGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESYGENRK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTG+QEQ+GSAD+DLVHIIAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGEQEQKGSADVDLVHIIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+P++EVIVDILNQKWDHERTKFS
Sbjct: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPVQEVIVDILNQKWDHERTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSD Q+SLDTWRKLS+GNSELETQL  LSK
Sbjct: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDPQKSLDTWRKLSQGNSELETQLTMLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAEHWD+YKYIIN C  LTSE+WI QA+EPSQQ IIKALLGARNAML+IRHHMRLMGEA
Sbjct: 361 LAAEHWDSYKYIINRCSILTSEQWIHQASEPSQQIIIKALLGARNAMLEIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDST+NVIKSWS LD LA
Sbjct: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTNNVIKSWSKLDTLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDPRGVALE+CDPRTKAITSAVSS+HI
Sbjct: 481 LLVREDPRGVALESCDPRTKAITSAVSSVHI 507

[Close]

BLAST of HG10012189 vs. ExPASy TrEMBL
Match: A0A6J1DT44 (Phosphomevalonate kinase OS=Momordica charantia OX=3673 GN=LOC111024139 PE=4 SV=1)

HSP 1 Score: 903.3 bits (2333), Expect = 4.7e-259
Identity = 460/511 (90.02%), Postives = 487/511 (95.30%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLE+PNAGLVLSTNARFYAIVKP YEEIKPDSWAWSWTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLERPNAGLVLSTNARFYAIVKPLYEEIKPDSWAWSWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQLLRES YKLSLKNQSLQSVSP     QSRNPFVE+AVEYCVAAACAKFV+KDNKDA
Sbjct: 61  TSPQLLRESTYKLSLKNQSLQSVSPS----QSRNPFVEKAVEYCVAAACAKFVNKDNKDA 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLL+QGLDITI+G NEFYSYR+QIEARGLPLTSESLASLPPFSSITFNDEES+GK CK
Sbjct: 121 LHKLLVQGLDITILGSNEFYSYRNQIEARGLPLTSESLASLPPFSSITFNDEESYGKVCK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMTAAVVAALLNYLGVV+LSLLT DQEQ+G+ADLDLVH+IAQSAHCIA
Sbjct: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVHLSLLTDDQEQKGTADLDLVHMIAQSAHCIA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGK+GSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNG+PI+EVI+DILNQKW+HE+TKFS
Sbjct: 241 QGKIGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGIPIQEVIIDILNQKWNHEQTKFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLMTL+LGEPGVGGSSTPSMVGAV+KWQKSD Q+SLD WRKLSE NSELETQLN LSK
Sbjct: 301 LPPLMTLLLGEPGVGGSSTPSMVGAVRKWQKSDPQKSLDMWRKLSEANSELETQLNMLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LAAE+WDAYKYII+ CCKLTSEKWI QATEPSQQAIIKAL+GARNAML IRHHMRLMGEA
Sbjct: 361 LAAEYWDAYKYIISSCCKLTSEKWIHQATEPSQQAIIKALVGARNAMLGIRHHMRLMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           AGVPIEPDSQT LLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDIL 
Sbjct: 421 AGVPIEPDSQTNLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILG 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDP G+ALE+ DPRT AITSAVSS+ I
Sbjct: 481 LLVREDPHGIALESGDPRTNAITSAVSSVRI 507

[Close]

BLAST of HG10012189 vs. TAIR 10
Match: AT1G31910.1 (GHMP kinase family protein )

HSP 1 Score: 690.6 bits (1781), Expect = 9.2e-199
Identity = 357/511 (69.86%), Postives = 420/511 (82.19%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP  EE+KP+SWAW WTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQL RES+YKLSL + +LQSVS       SRNPFVE A++Y +AA  A    + +K++
Sbjct: 61  TSPQLSRESMYKLSLNHLTLQSVSAS----DSRNPFVEHAIQYAIAA--AHLATEKDKES 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+G N+FYSYR+QIE+ GLPLT ESL +L PF+SITFN  ES+G N K
Sbjct: 121 LHKLLLQGLDITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMT AVVAALL+YLGVV+LS     + + G +DLD++H+IAQ++HC+A
Sbjct: 181 PEVAKTGLGSSAAMTTAVVAALLHYLGVVDLS-DPCKEGKFGCSDLDVIHMIAQTSHCLA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVS AVYGSQRYVRFSPEVLS AQ A  G+P+ EVI  IL  KWD++RT+FS
Sbjct: 241 QGKVGSGFDVSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLM L LGEPG GGSSTPSMVGAVKKWQ SD +++ + W+ LS+ N ELET+LN LSK
Sbjct: 301 LPPLMNLFLGEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LA +HWD Y  +I  C  LTSEKW+L ATEP  +AIIK LL AR AML+IR  MR MGEA
Sbjct: 361 LAKDHWDVYLRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEA 420

Query: 421 AGVPIEPDSQTKLLDATMNMEGVLLAGVPGAGGFDAVFAVTLGDSTSNVIKSWSSLDILA 480
           A VPIEP+SQT+LLD+TM+ EGVLLAGVPGAGGFDA+FA+TLGDS + + ++WSS ++LA
Sbjct: 421 ASVPIEPESQTQLLDSTMSAEGVLLAGVPGAGGFDAIFAITLGDSGTKLTQAWSSHNVLA 480

Query: 481 LLVREDPRGVALETCDPRTKAITSAVSSLHI 512
           LLVREDP GV LE+ DPRT  ITS VSS+H+
Sbjct: 481 LLVREDPHGVCLESGDPRTTCITSGVSSIHL 504

[Close]

BLAST of HG10012189 vs. TAIR 10
Match: AT1G31910.2 (GHMP kinase family protein )

HSP 1 Score: 566.6 bits (1459), Expect = 2.0e-161
Identity = 296/424 (69.81%), Postives = 344/424 (81.13%), Query Frame = 0


Query: 1   MAVVASAPGKVLIAGGYLVLEKPNAGLVLSTNARFYAIVKPTYEEIKPDSWAWSWTDVKL 60
           MAVVASAPGKVL+ GGYLVLEKPNAGLVLSTNARFYAIVKP  EE+KP+SWAW WTDVKL
Sbjct: 1   MAVVASAPGKVLMTGGYLVLEKPNAGLVLSTNARFYAIVKPINEEVKPESWAWKWTDVKL 60

Query: 61  TSPQLLRESIYKLSLKNQSLQSVSPRQVNYQSRNPFVERAVEYCVAAACAKFVDKDNKDA 120
           TSPQL RES+YKLSL + +LQSVS       SRNPFVE A++Y +AA  A    + +K++
Sbjct: 61  TSPQLSRESMYKLSLNHLTLQSVSAS----DSRNPFVEHAIQYAIAA--AHLATEKDKES 120

Query: 121 LHKLLLQGLDITIVGCNEFYSYRSQIEARGLPLTSESLASLPPFSSITFNDEESHGKNCK 180
           LHKLLLQGLDITI+G N+FYSYR+QIE+ GLPLT ESL +L PF+SITFN  ES+G N K
Sbjct: 121 LHKLLLQGLDITILGSNDFYSYRNQIESAGLPLTPESLGTLAPFASITFNAAESNGANSK 180

Query: 181 PEVAKTGLGSSAAMTAAVVAALLNYLGVVNLSLLTGDQEQRGSADLDLVHIIAQSAHCIA 240
           PEVAKTGLGSSAAMT AVVAALL+YLGVV+LS     + + G +DLD++H+IAQ++HC+A
Sbjct: 181 PEVAKTGLGSSAAMTTAVVAALLHYLGVVDLS-DPCKEGKFGCSDLDVIHMIAQTSHCLA 240

Query: 241 QGKVGSGFDVSSAVYGSQRYVRFSPEVLSSAQAAKNGMPIEEVIVDILNQKWDHERTKFS 300
           QGKVGSGFDVS AVYGSQRYVRFSPEVLS AQ A  G+P+ EVI  IL  KWD++RT+FS
Sbjct: 241 QGKVGSGFDVSCAVYGSQRYVRFSPEVLSFAQVAVTGLPLNEVIGTILKGKWDNKRTEFS 300

Query: 301 LPPLMTLVLGEPGVGGSSTPSMVGAVKKWQKSDSQRSLDTWRKLSEGNSELETQLNTLSK 360
           LPPLM L LGEPG GGSSTPSMVGAVKKWQ SD +++ + W+ LS+ N ELET+LN LSK
Sbjct: 301 LPPLMNLFLGEPGSGGSSTPSMVGAVKKWQMSDPEKARENWQNLSDANLELETKLNDLSK 360

Query: 361 LAAEHWDAYKYIINGCCKLTSEKWILQATEPSQQAIIKALLGARNAMLQIRHHMRLMGEA 420
           LA +HWD Y  +I  C  LTSEKW+L ATEP  +AIIK LL AR AML+IR  MR MGEA
Sbjct: 361 LAKDHWDVYLRVIKSCSVLTSEKWVLHATEPINEAIIKELLEAREAMLRIRILMRQMGEA 417

Query: 421 AGVP 425
           A VP
Sbjct: 421 ASVP 417

The following BLAST results are available for this feature:

BLAST of HG10012189 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_038887930.1	1.0e-271	94.52	phosphomevalonate kinase, peroxisomal [Benincasa hispida]	[more]
XP_008466028.1	1.3e-271	95.11	PREDICTED: phosphomevalonate kinase [Cucumis melo] >KAA0038599.1 phosphomevalona...	[more]
XP_004136210.1	5.0e-271	94.72	phosphomevalonate kinase, peroxisomal [Cucumis sativus] >KAE8651424.1 hypothetic...	[more]
XP_023554025.1	3.4e-264	91.78	phosphomevalonate kinase, peroxisomal-like [Cucurbita pepo subsp. pepo]	[more]
XP_022963972.1	3.4e-264	91.78	phosphomevalonate kinase, peroxisomal-like [Cucurbita moschata] >XP_022963974.1 ...	[more]

BLAST of HG10012189 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9C6T1	1.3e-197	69.86	Phosphomevalonate kinase, peroxisomal OS=Arabidopsis thaliana OX=3702 GN=PMK PE=...	[more]
Q9UT88	2.5e-39	31.15	Probable phosphomevalonate kinase OS=Schizosaccharomyces pombe (strain 972 / ATC...	[more]
P24521	2.6e-36	29.85	Phosphomevalonate kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...	[more]
Q97UL6	5.0e-08	26.24	Phosphomevalonate kinase OS=Saccharolobus solfataricus (strain ATCC 35092 / DSM ...	[more]

BLAST of HG10012189 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A5D3E5W3	6.3e-272	95.11	Phosphomevalonate kinase OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffol...	[more]
A0A1S3CQ96	6.3e-272	95.11	Phosphomevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103503581 PE=4 SV=1	[more]
A0A6J1HGL2	1.7e-264	91.78	Phosphomevalonate kinase OS=Cucurbita moschata OX=3662 GN=LOC111464112 PE=4 SV=1	[more]
A0A6J1HTW0	1.1e-263	91.59	Phosphomevalonate kinase OS=Cucurbita maxima OX=3661 GN=LOC111466832 PE=4 SV=1	[more]
A0A6J1DT44	4.7e-259	90.02	Phosphomevalonate kinase OS=Momordica charantia OX=3673 GN=LOC111024139 PE=4 SV=...	[more]

BLAST of HG10012189 vs. TAIR 10


Match Name	E-value	Identity	Description
AT1G31910.1	9.2e-199	69.86	GHMP kinase family protein	[more]
AT1G31910.2	2.0e-161	69.81	GHMP kinase family protein	[more]

InterPro

Analysis Name: InterPro Annotations of Bottle gourd (Hangzhou Gourd) v1
Date Performed: 2022-08-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036554	GHMP kinase, C-terminal domain superfamily	GENE3D	3.30.70.890		coord: 314..482 e-value: 2.1E-5 score: 26.7
IPR014721	Ribosomal protein S5 domain 2-type fold, subgroup	GENE3D	3.30.230.10		coord: 1..311 e-value: 8.2E-38 score: 132.1
IPR016005	Phosphomevalonate kinase Erg8	PIRSF	PIRSF017288	PMK_GHMP_euk	coord: 1..502 e-value: 5.1E-198 score: 656.4
IPR016005	Phosphomevalonate kinase Erg8	TIGRFAM	TIGR01219	TIGR01219	coord: 4..499 e-value: 3.4E-168 score: 558.2
IPR013750	GHMP kinase, C-terminal domain	PFAM	PF08544	GHMP_kinases_C	coord: 403..473 e-value: 3.3E-7 score: 30.6
IPR006204	GHMP kinase N-terminal domain	PFAM	PF00288	GHMP_kinases_N	coord: 179..257 e-value: 1.1E-16 score: 60.8
IPR035102	Phosphomevalonate kinase	PANTHER	PTHR31814	FAMILY NOT NAMED	coord: 1..510
None	No IPR available	PANTHER	PTHR31814:SF6	SUBFAMILY NOT NAMED	coord: 1..510
IPR020568	Ribosomal protein S5 domain 2-type fold	SUPERFAMILY	54211	Ribosomal protein S5 domain 2-like	coord: 3..317

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
HG10012189.1	HG10012189.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
biological_process	GO:0016310	phosphorylation
cellular_component	GO:0005777	peroxisome
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004631	phosphomevalonate kinase activity