HG10011270 (gene) Bottle gourd (Hangzhou Gourd) v1

Overview
NameHG10011270
Typegene
OrganismLagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
DescriptionTHO complex subunit 4D
LocationChr01: 4260460 .. 4262030 (-)
RNA-Seq ExpressionHG10011270
SyntenyHG10011270
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGTTTGATGAAAAGAAACATAGTCTGCTACAGATGTTGAGCAATATTAATATTTGTTGGGTATATGCAGGCCTGAATCTGGTCGTACTGCTAGCTCCAGCGTGGCCAACCCTTTTCCTGGGTAAGTTCTAACTGGACATTGCTTTCGGCATGAAATTTTTACATTCAATAGTGGAGTAGCTGGGTTTTTCTTTTATTATTATTATTATTATTATTATTATTATTATTAAAATTCTAGTTAAGTTCTGGGATTGTTTTACTGCCTTCTAGTTGGATTGGTTTTGAAGTCATTTGTCCTTGACTTCTTGGTTACTCGTTTCTCTGATTTTCTTAGGGGTGTTAGAACTGAGAGTTACATCTTTTAGTTAGAACTGAGAGTTATATCTTTTCTACCTGTTCGGAAGGGTGGAAGACAAGCTAATAAGTTCTTTCCTTTTTTTTCCCTAGTAAAAATATTTTTTTGTTAGAAAATTATCTGGTAAGATAATATTTAATACAGTTTTTAGAAAAAGTGGATAAAAGATGTTAGTGATAGTAGTGCAATGCTTTTGTGTGTGTTTTTAAATTAAATCAACTGTTTAAATATGCCTGAATTGTTTTAAATCTTTTATTATTATTTTTCCTTTTTAATTAGAAACAAGACAAAATAAAATATATTAATGAAAAGAGAACATAACCTAAAGGTCTACAGGTACGGGATGAGGTGTCCCTAAGCCTCATTTGAGGAATTGGCAAAAGCCCTCCAATGTGTATTACAATAAGGATTGTGCAAAGCGCTCCATGCAGATGCAGTAAGCTGTACATTTTCACCAAGTGTCAATAAGGATTTTTGTGTCTAATAGGTTCTTGACCTATTCAATAGTTGCCTAAAATTCACGGATCTACTAGCATACAAAATTGAAAGTTTAGGGTTCCATTAGATTAAAATTAAAATTTATATCTATTAGAACATAAACCTTCTTTAAAAGTTTGATTTTGCTAGACATTTATTTGACAAAGAAAGCAATCTAGGTAGGATATTTGATTTTTAAAACTGGATGAGTTTGAGGCATTCTTGAAAGTAGTCAGTTGAGGTATGCCCTTTGAAGGGTGCTTTTTTTTTCTTTTTCTTTTTTTGGGATAGGATCGAATGGGTTGCTGGTTTAAATCTCAACTCATGTATTTATATTTGTTTTATTCTTATATTTTGGTTTTAAAAAGGAGTGATGTTATATGTATGGTGGCTCAGCTTCTGTGGCCAAGTCTTTAAAAATGTACGTCATGAGTTGGAAATGGAGTAAGATGAATGAACTTTGCTTGAATTGGTTGAACTTGTTTTCATTGCTGTCTAGTTTTACTAAAGTTCTTCGGTTTTGTATAGTCCAAGCCATCGTGGAGGGCTGAGGAATGGCCGTGGCCGTGGTCGAGGTGGCTGGAGCCGTGGTCTAGGTCTAGGTCTAGGAGGAGGAGGAGGCCGTGGCCGAGGGCGTGGTCGTGGGCGTGGCCAGGGAAGAAAGAAACCTGTGGAGAAGTCCTCAGATGAACTTGACAAGGAGCTTGAAAACTACCATGCAGAAGCCATGCAAACCTGA

mRNA sequence

ATGTTTGATGAAAAGAAACATAGTCTGCTACAGATGTTGAGCAATATTAATATTTGTTGGGTATATGCAGGCCTGAATCTGGTCGTACTGCTAGCTCCAGCGTGGCCAACCCTTTTCCTGGGAGTGATGTTATATGTATGGTGGCTCAGCTTCTGTGGCCAAGTCTTTAAAAATGTACGTCATGAGTTGGAAATGGATCCAAGCCATCGTGGAGGGCTGAGGAATGGCCGTGGCCGTGGTCGAGGTGGCTGGAGCCGTGGTCTAGGTCTAGGTCTAGGAGGAGGAGGAGGCCGTGGCCGAGGGCGTGGTCGTGGGCGTGGCCAGGGAAGAAAGAAACCTGTGGAGAAGTCCTCAGATGAACTTGACAAGGAGCTTGAAAACTACCATGCAGAAGCCATGCAAACCTGA

Coding sequence (CDS)

ATGTTTGATGAAAAGAAACATAGTCTGCTACAGATGTTGAGCAATATTAATATTTGTTGGGTATATGCAGGCCTGAATCTGGTCGTACTGCTAGCTCCAGCGTGGCCAACCCTTTTCCTGGGAGTGATGTTATATGTATGGTGGCTCAGCTTCTGTGGCCAAGTCTTTAAAAATGTACGTCATGAGTTGGAAATGGATCCAAGCCATCGTGGAGGGCTGAGGAATGGCCGTGGCCGTGGTCGAGGTGGCTGGAGCCGTGGTCTAGGTCTAGGTCTAGGAGGAGGAGGAGGCCGTGGCCGAGGGCGTGGTCGTGGGCGTGGCCAGGGAAGAAAGAAACCTGTGGAGAAGTCCTCAGATGAACTTGACAAGGAGCTTGAAAACTACCATGCAGAAGCCATGCAAACCTGA

Protein sequence

MFDEKKHSLLQMLSNINICWVYAGLNLVVLLAPAWPTLFLGVMLYVWWLSFCGQVFKNVRHELEMDPSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELENYHAEAMQT
Homology
BLAST of HG10011270 vs. NCBI nr
Match: XP_038896761.1 (THO complex subunit 4D-like [Benincasa hispida])

HSP 1 Score: 115.9 bits (289), Expect = 2.7e-22
Identity = 65/69 (94.20%), Postives = 67/69 (97.10%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PSHRGGLRNGRGRGRGGW+RG G+G GGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE
Sbjct: 218 PSHRGGLRNGRGRGRGGWNRGQGVG-GGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 277

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 278 NYHAEAMQT 285

BLAST of HG10011270 vs. NCBI nr
Match: XP_004145851.1 (THO complex subunit 4D [Cucumis sativus] >KAE8650594.1 hypothetical protein Csa_011773 [Cucumis sativus])

HSP 1 Score: 115.9 bits (289), Expect = 2.7e-22
Identity = 64/69 (92.75%), Postives = 65/69 (94.20%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PSHRGGLRN RGRGRG WSRG+GLG G GGGRGRGRGRGRGQGRKKPVEKSSDELDKELE
Sbjct: 218 PSHRGGLRNARGRGRGAWSRGVGLGGGSGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 277

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 278 NYHAEAMQT 286

BLAST of HG10011270 vs. NCBI nr
Match: XP_008457020.1 (PREDICTED: THO complex subunit 4D [Cucumis melo])

HSP 1 Score: 111.3 bits (277), Expect = 6.5e-21
Identity = 63/69 (91.30%), Postives = 65/69 (94.20%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PSHRGGLRN RGRGRG W+RG+GLG G GGGRGRGRGRGRGQGRKKPVEKSSDELDKELE
Sbjct: 218 PSHRGGLRNARGRGRGAWTRGVGLG-GSGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 277

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 278 NYHAEAMQT 285

BLAST of HG10011270 vs. NCBI nr
Match: XP_022935328.1 (THO complex subunit 4D-like [Cucurbita moschata] >XP_022935329.1 THO complex subunit 4D-like [Cucurbita moschata] >XP_022935330.1 THO complex subunit 4D-like [Cucurbita moschata])

HSP 1 Score: 99.8 bits (247), Expect = 2.0e-17
Identity = 65/78 (83.33%), Postives = 66/78 (84.62%), Query Frame = 0

Query: 67  PSHRGGLRN--GRGRGRGGWSRGLGLGLG---GGGGRGRGR----GRGRGQGRKKPVEKS 126
           PSHRGGLR+  GRGRGRGGWSRGLG G G   GGGGRGRGR    GRGRGQGRKKPVEKS
Sbjct: 218 PSHRGGLRSGRGRGRGRGGWSRGLGGGGGRGLGGGGRGRGRGSGSGRGRGQGRKKPVEKS 277

Query: 127 SDELDKELENYHAEAMQT 136
           S ELDKELENYHAEAMQT
Sbjct: 278 SAELDKELENYHAEAMQT 295

BLAST of HG10011270 vs. NCBI nr
Match: XP_023527122.1 (THO complex subunit 4D [Cucurbita pepo subsp. pepo])

HSP 1 Score: 99.8 bits (247), Expect = 2.0e-17
Identity = 65/78 (83.33%), Postives = 66/78 (84.62%), Query Frame = 0

Query: 67  PSHRGGLRN--GRGRGRGGWSRGLGLGLG---GGGGRGRGR----GRGRGQGRKKPVEKS 126
           PSHRGGLR+  GRGRGRGGWSRGLG G G   GGGGRGRGR    GRGRGQGRKKPVEKS
Sbjct: 218 PSHRGGLRSGRGRGRGRGGWSRGLGGGGGRGLGGGGRGRGRGSGSGRGRGQGRKKPVEKS 277

Query: 127 SDELDKELENYHAEAMQT 136
           S ELDKELENYHAEAMQT
Sbjct: 278 SAELDKELENYHAEAMQT 295

BLAST of HG10011270 vs. ExPASy Swiss-Prot
Match: Q6NQ72 (THO complex subunit 4D OS=Arabidopsis thaliana OX=3702 GN=ALY4 PE=1 SV=1)

HSP 1 Score: 49.7 bits (117), Expect = 3.1e-05
Identity = 40/77 (51.95%), Postives = 48/77 (62.34%), Query Frame = 0

Query: 59  VRHELEMDPSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSS 118
           V   L +     GG+R GRG   G  +RG      G GGRGRG GRG G   KKPVEKS+
Sbjct: 222 VSRRLPIHNQQGGGMRGGRG---GFRARG-----RGNGGRGRGGGRGNG---KKPVEKSA 281

Query: 119 DELDKELENYHAEAMQT 136
            +LDK+LE+YHA+AM T
Sbjct: 282 ADLDKDLESYHADAMNT 287

BLAST of HG10011270 vs. ExPASy Swiss-Prot
Match: Q94EH8 (THO complex subunit 4C OS=Arabidopsis thaliana OX=3702 GN=ALY3 PE=1 SV=1)

HSP 1 Score: 47.0 bits (110), Expect = 2.0e-04
Identity = 43/79 (54.43%), Postives = 49/79 (62.03%), Query Frame = 0

Query: 70  RGGLRNGRGRGRGGWSR----------GLGLGLGGGGGRGRGRGRGR-----GQGRKKPV 129
           RGG R GRGRG G   R          G+  G GG  GRGRG G GR     G+G KKPV
Sbjct: 215 RGG-RVGRGRGSGPSGRRLPLQQNQQGGVTAGRGGFRGRGRGNGGGRGNKSGGRGGKKPV 274

Query: 130 EKSSDELDKELENYHAEAM 134
           EKS+ +LDK+LE+YHAEAM
Sbjct: 275 EKSAADLDKDLESYHAEAM 292

BLAST of HG10011270 vs. ExPASy TrEMBL
Match: A0A0A0LCJ7 (FoP_duplication domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_3G302110 PE=4 SV=1)

HSP 1 Score: 115.9 bits (289), Expect = 1.3e-22
Identity = 64/69 (92.75%), Postives = 65/69 (94.20%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PSHRGGLRN RGRGRG WSRG+GLG G GGGRGRGRGRGRGQGRKKPVEKSSDELDKELE
Sbjct: 42  PSHRGGLRNARGRGRGAWSRGVGLGGGSGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 101

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 102 NYHAEAMQT 110

BLAST of HG10011270 vs. ExPASy TrEMBL
Match: A0A1S3C452 (THO complex subunit 4D OS=Cucumis melo OX=3656 GN=LOC103496802 PE=4 SV=1)

HSP 1 Score: 111.3 bits (277), Expect = 3.2e-21
Identity = 63/69 (91.30%), Postives = 65/69 (94.20%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PSHRGGLRN RGRGRG W+RG+GLG G GGGRGRGRGRGRGQGRKKPVEKSSDELDKELE
Sbjct: 218 PSHRGGLRNARGRGRGAWTRGVGLG-GSGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 277

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 278 NYHAEAMQT 285

BLAST of HG10011270 vs. ExPASy TrEMBL
Match: A0A6J1J564 (THO complex subunit 4D-like OS=Cucurbita maxima OX=3661 GN=LOC111481464 PE=4 SV=1)

HSP 1 Score: 99.8 bits (247), Expect = 9.5e-18
Identity = 66/88 (75.00%), Postives = 67/88 (76.14%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGL----GLGLGGGG-------GRGRGR--------GRGRG 126
           PSHRGGLR+GRGRGRGGWSRGL    G GLGGGG       GRGRGR        GRGRG
Sbjct: 218 PSHRGGLRSGRGRGRGGWSRGLGGGGGRGLGGGGGRGLGGRGRGRGRGSGSGSGSGRGRG 277

Query: 127 QGRKKPVEKSSDELDKELENYHAEAMQT 136
           QGRKKPVEKSS ELDKELENYHAEAMQT
Sbjct: 278 QGRKKPVEKSSAELDKELENYHAEAMQT 305

BLAST of HG10011270 vs. ExPASy TrEMBL
Match: A0A6J1FAB9 (THO complex subunit 4D-like OS=Cucurbita moschata OX=3662 GN=LOC111442248 PE=4 SV=1)

HSP 1 Score: 99.8 bits (247), Expect = 9.5e-18
Identity = 65/78 (83.33%), Postives = 66/78 (84.62%), Query Frame = 0

Query: 67  PSHRGGLRN--GRGRGRGGWSRGLGLGLG---GGGGRGRGR----GRGRGQGRKKPVEKS 126
           PSHRGGLR+  GRGRGRGGWSRGLG G G   GGGGRGRGR    GRGRGQGRKKPVEKS
Sbjct: 218 PSHRGGLRSGRGRGRGRGGWSRGLGGGGGRGLGGGGRGRGRGSGSGRGRGQGRKKPVEKS 277

Query: 127 SDELDKELENYHAEAMQT 136
           S ELDKELENYHAEAMQT
Sbjct: 278 SAELDKELENYHAEAMQT 295

BLAST of HG10011270 vs. ExPASy TrEMBL
Match: A0A6J1CP51 (THO complex subunit 4D-like OS=Momordica charantia OX=3673 GN=LOC111013262 PE=4 SV=1)

HSP 1 Score: 89.0 bits (219), Expect = 1.7e-14
Identity = 57/69 (82.61%), Postives = 59/69 (85.51%), Query Frame = 0

Query: 67  PSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSSDELDKELE 126
           PS+RG LR GRGRGRGGWSRG G     GGGRGRGRGRGRG GRKK VEKSSDELDK+LE
Sbjct: 217 PSNRGALR-GRGRGRGGWSRGQG---QVGGGRGRGRGRGRGLGRKKTVEKSSDELDKDLE 276

Query: 127 NYHAEAMQT 136
           NYHAEAMQT
Sbjct: 277 NYHAEAMQT 281

BLAST of HG10011270 vs. TAIR 10
Match: AT5G37720.1 (ALWAYS EARLY 4 )

HSP 1 Score: 49.7 bits (117), Expect = 2.2e-06
Identity = 40/77 (51.95%), Postives = 48/77 (62.34%), Query Frame = 0

Query: 59  VRHELEMDPSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSS 118
           V   L +     GG+R GRG   G  +RG      G GGRGRG GRG G   KKPVEKS+
Sbjct: 222 VSRRLPIHNQQGGGMRGGRG---GFRARG-----RGNGGRGRGGGRGNG---KKPVEKSA 281

Query: 119 DELDKELENYHAEAMQT 136
            +LDK+LE+YHA+AM T
Sbjct: 282 ADLDKDLESYHADAMNT 287

BLAST of HG10011270 vs. TAIR 10
Match: AT5G37720.2 (ALWAYS EARLY 4 )

HSP 1 Score: 49.7 bits (117), Expect = 2.2e-06
Identity = 40/77 (51.95%), Postives = 48/77 (62.34%), Query Frame = 0

Query: 59  VRHELEMDPSHRGGLRNGRGRGRGGWSRGLGLGLGGGGGRGRGRGRGRGQGRKKPVEKSS 118
           V   L +     GG+R GRG   G  +RG      G GGRGRG GRG G   KKPVEKS+
Sbjct: 214 VSRRLPIHNQQGGGMRGGRG---GFRARG-----RGNGGRGRGGGRGNG---KKPVEKSA 273

Query: 119 DELDKELENYHAEAMQT 136
            +LDK+LE+YHA+AM T
Sbjct: 274 ADLDKDLESYHADAMNT 279

BLAST of HG10011270 vs. TAIR 10
Match: AT1G66260.1 (RNA-binding (RRM/RBD/RNP motifs) family protein )

HSP 1 Score: 47.0 bits (110), Expect = 1.4e-05
Identity = 43/79 (54.43%), Postives = 49/79 (62.03%), Query Frame = 0

Query: 70  RGGLRNGRGRGRGGWSR----------GLGLGLGGGGGRGRGRGRGR-----GQGRKKPV 129
           RGG R GRGRG G   R          G+  G GG  GRGRG G GR     G+G KKPV
Sbjct: 215 RGG-RVGRGRGSGPSGRRLPLQQNQQGGVTAGRGGFRGRGRGNGGGRGNKSGGRGGKKPV 274

Query: 130 EKSSDELDKELENYHAEAM 134
           EKS+ +LDK+LE+YHAEAM
Sbjct: 275 EKSAADLDKDLESYHAEAM 292

BLAST of HG10011270 vs. TAIR 10
Match: AT1G66260.2 (RNA-binding (RRM/RBD/RNP motifs) family protein )

HSP 1 Score: 47.0 bits (110), Expect = 1.4e-05
Identity = 43/79 (54.43%), Postives = 49/79 (62.03%), Query Frame = 0

Query: 70  RGGLRNGRGRGRGGWSR----------GLGLGLGGGGGRGRGRGRGR-----GQGRKKPV 129
           RGG R GRGRG G   R          G+  G GG  GRGRG G GR     G+G KKPV
Sbjct: 215 RGG-RVGRGRGSGPSGRRLPLQQNQQGGVTAGRGGFRGRGRGNGGGRGNKSGGRGGKKPV 274

Query: 130 EKSSDELDKELENYHAEAM 134
           EKS+ +LDK+LE+YHAEAM
Sbjct: 275 EKSAADLDKDLESYHAEAM 292

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_038896761.12.7e-2294.20THO complex subunit 4D-like [Benincasa hispida][more]
XP_004145851.12.7e-2292.75THO complex subunit 4D [Cucumis sativus] >KAE8650594.1 hypothetical protein Csa_... [more]
XP_008457020.16.5e-2191.30PREDICTED: THO complex subunit 4D [Cucumis melo][more]
XP_022935328.12.0e-1783.33THO complex subunit 4D-like [Cucurbita moschata] >XP_022935329.1 THO complex sub... [more]
XP_023527122.12.0e-1783.33THO complex subunit 4D [Cucurbita pepo subsp. pepo][more]
Match NameE-valueIdentityDescription
Q6NQ723.1e-0551.95THO complex subunit 4D OS=Arabidopsis thaliana OX=3702 GN=ALY4 PE=1 SV=1[more]
Q94EH82.0e-0454.43THO complex subunit 4C OS=Arabidopsis thaliana OX=3702 GN=ALY3 PE=1 SV=1[more]
Match NameE-valueIdentityDescription
A0A0A0LCJ71.3e-2292.75FoP_duplication domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_3G30... [more]
A0A1S3C4523.2e-2191.30THO complex subunit 4D OS=Cucumis melo OX=3656 GN=LOC103496802 PE=4 SV=1[more]
A0A6J1J5649.5e-1875.00THO complex subunit 4D-like OS=Cucurbita maxima OX=3661 GN=LOC111481464 PE=4 SV=... [more]
A0A6J1FAB99.5e-1883.33THO complex subunit 4D-like OS=Cucurbita moschata OX=3662 GN=LOC111442248 PE=4 S... [more]
A0A6J1CP511.7e-1482.61THO complex subunit 4D-like OS=Momordica charantia OX=3673 GN=LOC111013262 PE=4 ... [more]
Match NameE-valueIdentityDescription
AT5G37720.12.2e-0651.95ALWAYS EARLY 4 [more]
AT5G37720.22.2e-0651.95ALWAYS EARLY 4 [more]
AT1G66260.11.4e-0554.43RNA-binding (RRM/RBD/RNP motifs) family protein [more]
AT1G66260.21.4e-0554.43RNA-binding (RRM/RBD/RNP motifs) family protein [more]
InterPro
Analysis Name: InterPro Annotations of Bottle gourd (Hangzhou Gourd) v1
Date Performed: 2022-08-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR025715Chromatin target of PRMT1 protein, C-terminalSMARTSM01218FoP_duplication_2coord: 65..135
e-value: 2.2E-9
score: 47.2
IPR025715Chromatin target of PRMT1 protein, C-terminalPFAMPF13865FoP_duplicationcoord: 72..130
e-value: 4.5E-7
score: 30.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 67..135
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 108..129

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
HG10011270.1HG10011270.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006406 mRNA export from nucleus
cellular_component GO:0005634 nucleus
molecular_function GO:0003729 mRNA binding