HG10009525 (gene) Bottle gourd (Hangzhou Gourd) v1

Overview


Name	HG10009525
Type	gene
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	Unknown protein
Location	Chr06: 7060601 .. 7061062 (+)
RNA-Seq Expression	HG10009525
Synteny	HG10009525

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGAAATCCATTAATTCCCTTTCAATCTCCTCCACCAATTCCGCTTCCTTCCTCTTCCCTTCCACTTCCTCCGGCCACCACCGCCGCCGGCTACCAGTGGCCGGAATCGTAAGGGCGTCGAGAGAAGCAGCCGACAACAACAATAATTACTACGCGAGCGGGAAAGTAGTAGACGAGAGCATGATCGTGCTCCGGAAACGAATCCACGAGATCAAGATGGCGGAGCAAAGCCACGATCCGCCGGCGGATTGGTTTGATTGGGAGAAACGGTATTATTCCGATTACGATTCTCATATCTGTGAGGCTTTAGGCTATCTTCAATCTCATTTGATGAATACTCGCCCTAGCGTCGCCTTGGGAATGCTCCTTGTTATTACTCTCAGCGTTCCGCTTTCCTCCGCCCTTCTTCTCCACCACTTCTTCCAAATCGCCGTCGCGCTTCTCGCCGCTTTCCATCCCTAA

mRNA sequence

ATGAAATCCATTAATTCCCTTTCAATCTCCTCCACCAATTCCGCTTCCTTCCTCTTCCCTTCCACTTCCTCCGGCCACCACCGCCGCCGGCTACCAGTGGCCGGAATCGTAAGGGCGTCGAGAGAAGCAGCCGACAACAACAATAATTACTACGCGAGCGGGAAAGTAGTAGACGAGAGCATGATCGTGCTCCGGAAACGAATCCACGAGATCAAGATGGCGGAGCAAAGCCACGATCCGCCGGCGGATTGGTTTGATTGGGAGAAACGGTATTATTCCGATTACGATTCTCATATCTGTGAGGCTTTAGGCTATCTTCAATCTCATTTGATGAATACTCGCCCTAGCGTCGCCTTGGGAATGCTCCTTGTTATTACTCTCAGCGTTCCGCTTTCCTCCGCCCTTCTTCTCCACCACTTCTTCCAAATCGCCGTCGCGCTTCTCGCCGCTTTCCATCCCTAA

Coding sequence (CDS)

ATGAAATCCATTAATTCCCTTTCAATCTCCTCCACCAATTCCGCTTCCTTCCTCTTCCCTTCCACTTCCTCCGGCCACCACCGCCGCCGGCTACCAGTGGCCGGAATCGTAAGGGCGTCGAGAGAAGCAGCCGACAACAACAATAATTACTACGCGAGCGGGAAAGTAGTAGACGAGAGCATGATCGTGCTCCGGAAACGAATCCACGAGATCAAGATGGCGGAGCAAAGCCACGATCCGCCGGCGGATTGGTTTGATTGGGAGAAACGGTATTATTCCGATTACGATTCTCATATCTGTGAGGCTTTAGGCTATCTTCAATCTCATTTGATGAATACTCGCCCTAGCGTCGCCTTGGGAATGCTCCTTGTTATTACTCTCAGCGTTCCGCTTTCCTCCGCCCTTCTTCTCCACCACTTCTTCCAAATCGCCGTCGCGCTTCTCGCCGCTTTCCATCCCTAA

Protein sequence

MKSINSLSISSTNSASFLFPSTSSGHHRRRLPVAGIVRASREAADNNNNYYASGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP

Homology

[Close]

BLAST of HG10009525 vs. NCBI nr
Match: XP_038875502.1 (uncharacterized protein LOC120067929 [Benincasa hispida])

HSP 1 Score: 238.0 bits (606), Expect = 5.2e-59
Identity = 132/157 (84.08%), Postives = 139/157 (88.54%), Query Frame = 0


Query: 1   MKSINSL--SISSTNSASFLFPSTSSGHHRRRLPVAGIVRA-SREAAD-NNNNYYASGKV 60
           MKSINSL  SISSTNSA FLFPSTS+ H  RRLP+A  V A SR +AD NNNNYYASGKV
Sbjct: 1   MKSINSLDRSISSTNSAPFLFPSTSA-HRHRRLPLAVTVTASSRSSADKNNNNYYASGKV 60

Query: 61  VDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPS 120
           VDESMIVLRKRIHEIKMAEQSH+PPADW DWEKRYYSDYDSHICEALGYLQ+HLMNTRPS
Sbjct: 61  VDESMIVLRKRIHEIKMAEQSHEPPADWLDWEKRYYSDYDSHICEALGYLQTHLMNTRPS 120

Query: 121 VALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP 154
           VALGMLL+ITLSVP SSA+LLH FFQIA ALLA F P
Sbjct: 121 VALGMLLLITLSVPFSSAILLHRFFQIAAALLAGFSP 156

[Close]

BLAST of HG10009525 vs. NCBI nr
Match: KAA0046315.1 (uncharacterized protein E6C27_scaffold149G00240 [Cucumis melo var. makuwa])

HSP 1 Score: 208.4 bits (529), Expect = 4.4e-50
Identity = 121/161 (75.16%), Postives = 126/161 (78.26%), Query Frame = 0


Query: 1   MKSINSLSISSTNSASFLFPSTSSGHHRRRLPVAGIVRASRE-AADNNNN-------YYA 60
           MKSINSLS S   + S LF      H RR+   A  VRASRE AADNNNN       YYA
Sbjct: 1   MKSINSLSFS---TPSPLFSPAPHPHGRRKPLPAVTVRASREQAADNNNNNNNNYNDYYA 60

Query: 61  SGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMN 120
            GKVVDESMIVLRKRIHEIKMAEQ  +PPADW DWEKRYYSDYDSHICEALGYLQSHLMN
Sbjct: 61  GGKVVDESMIVLRKRIHEIKMAEQRQEPPADWLDWEKRYYSDYDSHICEALGYLQSHLMN 120

Query: 121 TRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP 154
           TRPSVALGMLL+I +SVPLSSALLLH FF IAVALLA F P
Sbjct: 121 TRPSVALGMLLLIIVSVPLSSALLLHRFFHIAVALLAGFSP 158

[Close]

BLAST of HG10009525 vs. NCBI nr
Match: XP_004150478.1 (uncharacterized protein LOC101215395 [Cucumis sativus])

HSP 1 Score: 203.8 bits (517), Expect = 1.1e-48
Identity = 115/161 (71.43%), Postives = 125/161 (77.64%), Query Frame = 0


Query: 1   MKSINSLSISSTNSASFLFPSTSSGHHRRRLPVAGIVRASREAA--------DNNNNYYA 60
           M+SINSLS S+ +    LF   +  H RR+   A  VRASRE A        +NNNNYYA
Sbjct: 1   MESINSLSFSTPS----LFSPAAHPHVRRKPLPAVTVRASREQAADSNNNNKNNNNNYYA 60

Query: 61  SGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMN 120
            GKVVDESMIVLRKRIHEIKMAEQ  +PPADW DWEKR+YSDYDSHICEALGYLQSHLMN
Sbjct: 61  GGKVVDESMIVLRKRIHEIKMAEQRQEPPADWLDWEKRWYSDYDSHICEALGYLQSHLMN 120

Query: 121 TRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP 154
           TRPSVALGMLL+I +SVPLSSALLLH F  IAVALLA F P
Sbjct: 121 TRPSVALGMLLLIIISVPLSSALLLHRFLHIAVALLAGFSP 157

[Close]

BLAST of HG10009525 vs. NCBI nr
Match: XP_022993164.1 (uncharacterized protein LOC111489262 [Cucurbita maxima])

HSP 1 Score: 201.1 bits (510), Expect = 7.1e-48
Identity = 108/149 (72.48%), Postives = 122/149 (81.88%), Query Frame = 0


Query: 8   SISSTNSASFL--FPSTSSGHHRRRLPVAGIVRASREA-----ADNNNNYYASGKVVDES 67
           SISS NSA FL   P + S   RRRLP+  ++ +SR A      +NNNNYYASGK+VDES
Sbjct: 3   SISSANSAPFLHFHPISPSSRRRRRLPLFTVIASSRGADSSSSNNNNNNYYASGKLVDES 62

Query: 68  MIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALG 127
           MIVLRKRIHEIKM EQSH+PP+DW DWEKR YSDYDSHICEALGYLQSHLMNTRPSV+LG
Sbjct: 63  MIVLRKRIHEIKMVEQSHEPPSDWLDWEKRCYSDYDSHICEALGYLQSHLMNTRPSVSLG 122

Query: 128 MLLVITLSVPLSSALLLHHFFQIAVALLA 150
           +LL+ITLSVPLSSA++LH F  IA ALLA
Sbjct: 123 ILLLITLSVPLSSAVILHRFIDIAAALLA 151

[Close]

BLAST of HG10009525 vs. NCBI nr
Match: XP_008437695.1 (PREDICTED: uncharacterized protein LOC103483039, partial [Cucumis melo])

HSP 1 Score: 201.1 bits (510), Expect = 7.1e-48
Identity = 109/136 (80.15%), Postives = 114/136 (83.82%), Query Frame = 0


Query: 27  HRRRLPVAGI-VRASRE-AADNNNN-------YYASGKVVDESMIVLRKRIHEIKMAEQS 86
           H RR P+  + VRASRE AADNNNN       YYA GKVVDESMIVLRKRIHEIKMAEQ 
Sbjct: 18  HGRRKPLPAVTVRASREQAADNNNNNNNNYNDYYAGGKVVDESMIVLRKRIHEIKMAEQR 77

Query: 87  HDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLLVITLSVPLSSALLL 146
            +PPADW DWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLL+I +SVPLSSALLL
Sbjct: 78  QEPPADWLDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLLLIIVSVPLSSALLL 137

Query: 147 HHFFQIAVALLAAFHP 154
           H FF IAVALLA F P
Sbjct: 138 HRFFHIAVALLAGFSP 153

[Close]

BLAST of HG10009525 vs. ExPASy TrEMBL
Match: A0A5A7TY46 (Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold149G00240 PE=4 SV=1)

HSP 1 Score: 208.4 bits (529), Expect = 2.2e-50
Identity = 121/161 (75.16%), Postives = 126/161 (78.26%), Query Frame = 0


Query: 1   MKSINSLSISSTNSASFLFPSTSSGHHRRRLPVAGIVRASRE-AADNNNN-------YYA 60
           MKSINSLS S   + S LF      H RR+   A  VRASRE AADNNNN       YYA
Sbjct: 1   MKSINSLSFS---TPSPLFSPAPHPHGRRKPLPAVTVRASREQAADNNNNNNNNYNDYYA 60

Query: 61  SGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMN 120
            GKVVDESMIVLRKRIHEIKMAEQ  +PPADW DWEKRYYSDYDSHICEALGYLQSHLMN
Sbjct: 61  GGKVVDESMIVLRKRIHEIKMAEQRQEPPADWLDWEKRYYSDYDSHICEALGYLQSHLMN 120

Query: 121 TRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP 154
           TRPSVALGMLL+I +SVPLSSALLLH FF IAVALLA F P
Sbjct: 121 TRPSVALGMLLLIIVSVPLSSALLLHRFFHIAVALLAGFSP 158

[Close]

BLAST of HG10009525 vs. ExPASy TrEMBL
Match: A0A0A0KPI5 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_5G571480 PE=4 SV=1)

HSP 1 Score: 203.8 bits (517), Expect = 5.3e-49
Identity = 115/161 (71.43%), Postives = 125/161 (77.64%), Query Frame = 0


Query: 1   MKSINSLSISSTNSASFLFPSTSSGHHRRRLPVAGIVRASREAA--------DNNNNYYA 60
           M+SINSLS S+ +    LF   +  H RR+   A  VRASRE A        +NNNNYYA
Sbjct: 1   MESINSLSFSTPS----LFSPAAHPHVRRKPLPAVTVRASREQAADSNNNNKNNNNNYYA 60

Query: 61  SGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMN 120
            GKVVDESMIVLRKRIHEIKMAEQ  +PPADW DWEKR+YSDYDSHICEALGYLQSHLMN
Sbjct: 61  GGKVVDESMIVLRKRIHEIKMAEQRQEPPADWLDWEKRWYSDYDSHICEALGYLQSHLMN 120

Query: 121 TRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFHP 154
           TRPSVALGMLL+I +SVPLSSALLLH F  IAVALLA F P
Sbjct: 121 TRPSVALGMLLLIIISVPLSSALLLHRFLHIAVALLAGFSP 157

[Close]

BLAST of HG10009525 vs. ExPASy TrEMBL
Match: A0A6J1JZG1 (uncharacterized protein LOC111489262 OS=Cucurbita maxima OX=3661 GN=LOC111489262 PE=4 SV=1)

HSP 1 Score: 201.1 bits (510), Expect = 3.4e-48
Identity = 108/149 (72.48%), Postives = 122/149 (81.88%), Query Frame = 0


Query: 8   SISSTNSASFL--FPSTSSGHHRRRLPVAGIVRASREA-----ADNNNNYYASGKVVDES 67
           SISS NSA FL   P + S   RRRLP+  ++ +SR A      +NNNNYYASGK+VDES
Sbjct: 3   SISSANSAPFLHFHPISPSSRRRRRLPLFTVIASSRGADSSSSNNNNNNYYASGKLVDES 62

Query: 68  MIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALG 127
           MIVLRKRIHEIKM EQSH+PP+DW DWEKR YSDYDSHICEALGYLQSHLMNTRPSV+LG
Sbjct: 63  MIVLRKRIHEIKMVEQSHEPPSDWLDWEKRCYSDYDSHICEALGYLQSHLMNTRPSVSLG 122

Query: 128 MLLVITLSVPLSSALLLHHFFQIAVALLA 150
           +LL+ITLSVPLSSA++LH F  IA ALLA
Sbjct: 123 ILLLITLSVPLSSAVILHRFIDIAAALLA 151

[Close]

BLAST of HG10009525 vs. ExPASy TrEMBL
Match: A0A1S3AV87 (uncharacterized protein LOC103483039 OS=Cucumis melo OX=3656 GN=LOC103483039 PE=4 SV=1)

HSP 1 Score: 201.1 bits (510), Expect = 3.4e-48
Identity = 109/136 (80.15%), Postives = 114/136 (83.82%), Query Frame = 0


Query: 27  HRRRLPVAGI-VRASRE-AADNNNN-------YYASGKVVDESMIVLRKRIHEIKMAEQS 86
           H RR P+  + VRASRE AADNNNN       YYA GKVVDESMIVLRKRIHEIKMAEQ 
Sbjct: 18  HGRRKPLPAVTVRASREQAADNNNNNNNNYNDYYAGGKVVDESMIVLRKRIHEIKMAEQR 77

Query: 87  HDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLLVITLSVPLSSALLL 146
            +PPADW DWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLL+I +SVPLSSALLL
Sbjct: 78  QEPPADWLDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGMLLLIIVSVPLSSALLL 137

Query: 147 HHFFQIAVALLAAFHP 154
           H FF IAVALLA F P
Sbjct: 138 HRFFHIAVALLAGFSP 153

[Close]

BLAST of HG10009525 vs. ExPASy TrEMBL
Match: A0A6J1FMN3 (uncharacterized protein LOC111445338 OS=Cucurbita moschata OX=3662 GN=LOC111445338 PE=4 SV=1)

HSP 1 Score: 200.7 bits (509), Expect = 4.5e-48
Identity = 108/147 (73.47%), Postives = 122/147 (82.99%), Query Frame = 0


Query: 8   SISSTNSASFL--FPSTSSGHHRRRLPVAGIVRASREA---ADNNNNYYASGKVVDESMI 67
           SISS NSA FL   P +SS   RRR P+  ++ +SR A   + NNNNYYASGK+VDESMI
Sbjct: 3   SISSANSAPFLHFHPISSSSRRRRRPPLFTVMASSRGADSNSSNNNNYYASGKLVDESMI 62

Query: 68  VLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQSHLMNTRPSVALGML 127
           VLRKRIHEIKM E+SH+PP+DW DWEKR YSDYDSHICEALGYLQSHLMNTRPSVALG+L
Sbjct: 63  VLRKRIHEIKMVERSHEPPSDWLDWEKRCYSDYDSHICEALGYLQSHLMNTRPSVALGIL 122

Query: 128 LVITLSVPLSSALLLHHFFQIAVALLA 150
           L+ITLSVPLSSA++LH F  IA ALLA
Sbjct: 123 LLITLSVPLSSAVILHRFIDIAAALLA 149

[Close]

BLAST of HG10009525 vs. TAIR 10
Match: AT2G01300.1 (unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G15010.1); Has 73 Blast hits to 73 proteins in 12 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 73; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). )

HSP 1 Score: 122.5 bits (306), Expect = 3.0e-28
Identity = 58/114 (50.88%), Postives = 85/114 (74.56%), Query Frame = 0


Query: 37  VRASREAADNNNNYYASGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYD 96
           +R S  A+   ++YY  G++VDE+MIVLRKRIHE+KM E++++PP+ W DWEKR+Y+ YD
Sbjct: 36  MRVSAAASSGKDHYYGGGRLVDENMIVLRKRIHEMKMVERNYEPPSHWMDWEKRFYNSYD 95

Query: 97  SHICEALGYLQSHLMNTRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAA 151
           S IC+++G LQS LMN+RP+VA+  LL + +SVP+SS ++      +   LLAA
Sbjct: 96  SVICDSVGLLQSFLMNSRPTVAIATLLFLLVSVPVSSTVIAFRLIDLLHWLLAA 149

[Close]

BLAST of HG10009525 vs. TAIR 10
Match: AT1G15010.1 (unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G01300.1); Has 71 Blast hits to 71 proteins in 13 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 69; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). )

HSP 1 Score: 115.9 bits (289), Expect = 2.8e-26
Identity = 55/104 (52.88%), Postives = 77/104 (74.04%), Query Frame = 0


Query: 49  NYYASGKVVDESMIVLRKRIHEIKMAEQSHDPPADWFDWEKRYYSDYDSHICEALGYLQS 108
           +YY  G+ VDE+M+VLRKRIHE+KM E++ +PP+ W  WEKR+Y +YD+ IC+AL  LQ+
Sbjct: 37  DYYRGGRTVDENMVVLRKRIHEMKMVERNFEPPSHWMQWEKRFYCNYDATICDALTLLQT 96

Query: 109 HLMNTRPSVALGMLLVITLSVPLSSALLLHHFFQIAVALLAAFH 153
            LMN+RPSVA G  L++ +SVP+SSA+       +A+ LL A H
Sbjct: 97  FLMNSRPSVAFGTCLLLLVSVPVSSAVFAFRILDLALWLLDAVH 140

The following BLAST results are available for this feature:

BLAST of HG10009525 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_038875502.1	5.2e-59	84.08	uncharacterized protein LOC120067929 [Benincasa hispida]	[more]
KAA0046315.1	4.4e-50	75.16	uncharacterized protein E6C27_scaffold149G00240 [Cucumis melo var. makuwa]	[more]
XP_004150478.1	1.1e-48	71.43	uncharacterized protein LOC101215395 [Cucumis sativus]	[more]
XP_022993164.1	7.1e-48	72.48	uncharacterized protein LOC111489262 [Cucurbita maxima]	[more]
XP_008437695.1	7.1e-48	80.15	PREDICTED: uncharacterized protein LOC103483039, partial [Cucumis melo]	[more]

BLAST of HG10009525 vs. NCBI nr


Match Name	E-value	Identity	Description

BLAST of HG10009525 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A5A7TY46	2.2e-50	75.16	Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold...	[more]
A0A0A0KPI5	5.3e-49	71.43	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_5G571480 PE=4 SV=1	[more]
A0A6J1JZG1	3.4e-48	72.48	uncharacterized protein LOC111489262 OS=Cucurbita maxima OX=3661 GN=LOC111489262...	[more]
A0A1S3AV87	3.4e-48	80.15	uncharacterized protein LOC103483039 OS=Cucumis melo OX=3656 GN=LOC103483039 PE=...	[more]
A0A6J1FMN3	4.5e-48	73.47	uncharacterized protein LOC111445338 OS=Cucurbita moschata OX=3662 GN=LOC1114453...	[more]

BLAST of HG10009525 vs. TAIR 10


Match Name	E-value	Identity	Description
AT2G01300.1	3.0e-28	50.88	unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TA...	[more]
AT1G15010.1	2.8e-26	52.88	unknown protein; BEST Arabidopsis thaliana protein match is: unknown protein (TA...	[more]

InterPro

Analysis Name: InterPro Annotations of Bottle gourd (Hangzhou Gourd) v1
Date Performed: 2022-08-01

Position :

Zoom :

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PANTHER	PTHR33782	OS01G0121600 PROTEIN	coord: 1..152
None	No IPR available	PANTHER	PTHR33782:SF13	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT	coord: 1..152

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
HG10009525.1	HG10009525.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016021	integral component of membrane