CmoCh15G006910 (gene) Cucurbita moschata (Rifu) v1

Overview


Name	CmoCh15G006910
Type	gene
Organism	Cucurbita moschata (Cucurbita moschata (Rifu) v1)
Description	TLC domain-containing protein
Location	Cmo_Chr15: 3370321 .. 3373773 (+)
RNA-Seq Expression	CmoCh15G006910
Synteny	CmoCh15G006910

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRCDSpolypeptidethree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

CAATTCTCGTTTTCACCAGAAGATACAGAACAAGCGATTGAGCTCCATAGCGAATTAATGGCGGGGCGGACGGTGTTGAAGGAGAAGAGCAGGGCAGGAAGCTTCTTCTCCGCGACATTAGTGCTTTGGACGGTCTCTCTTTGGTTCGAAATTCTGTTCGACAGGCGCTTCGAGCTGCTCTACCTCGTATTCGGAGCTCTGTTCTACCAATCCGCCAATTCGGCCATTCGATTTCTTATTTCTAAGGAACCTCTTGTAGTCAACACCGCCGTCTCTCTCCTTCACTCTATTATCACTTCTGCTTCAGGTTCTGTGCCTACTCTTTTACCCTTTGTTGCTTGTTTTCCCTTCTACTTCTCTGTGAGTGAATTCATACCTTCAGTTGTTGTTTTTCGTCATACGTGACTGCCTTCCTTATTTACTGTTTGATTCTTTGTTTGGTGGTTACTTCTTTGGCTTGCTTGAAGGTTTAGCAATGGAATAATAAACTTTGTTTTCATTATAAGATAGACTGAGAGTTGATCGTGTTTGGTTATTGCAAGTTCTGTGTGGTAAATTGTGTGAATTATTAGGTATTAATGGTGATTGAGAGTTTGCAAGTGTGCTATTGTTTCTGGAAATCGGGATGTGGTTCAGTGCGTGTGCTACAGTGGGTTGTTTGAGACAATGAACCAAGCGCAAATGAATTTTTTGGAGTCCTTTTACAGCACCAAGAATATTTAGAGTTTGTTCTTTACTCCTGTAGCATTACTTTGGTCAAATTATAACACTAAACCCCAATTTTTAAGCCTAAGTTCTTGAATTTTAAATGAGATTTAGAAATAGTTAATATTACCTTTTGTTATATCCAAAATCAATCCGAAATAACTTAAAATCAATTCAAATGATATGAAAATGGTGATTGGAAGTGTAAATCAAACATTAAATTGATTTTGAATGATTAAATGCTTGATTTGGAGTGATTTTGAACATGACAAAAGTGCACTAAGTTGTCTTCCTCACACGAATTCGGTTAAAATTAATTCAGTCGACAAAAACTAAACAAAATAAATTTTAAATTTAGATACAGATCAGTCTAGAGGGCCATCCGTAGGACCTGTTAATCATAATGAAGATCTCTAACCTCAATACTCGTTTAAATCAAACAGGTCATTGTCATCTTGCTACACTACATAAAACAGTCTAACCCTGACTATTATGTGCTTGAAGGTTGTTTCTCAACCAAGAAAATGTCTAAAAACTCATGAATGATAAGAGAGATTCTCTCCTGGTTTCATTAGCAACTTCTTTGTATTGTTGAAGGTTGAGGAAAGCCTAAAGGAAAACTAACTATTTAATTGCCAGGGGAAAGGCTGCTAGGTTGGCCTTGGTTGCCACTTTATTCCAACCCAAAGGGCTTTTATTTTCTGAATTTCAATAGTTAATCCTATTCTTTGGGCCATCTAGTTAAGTCATCTTTATTTAATTGCAGTGTTGTTTGTTTTGGCAAATCGGTGGTTGAGTCATGGTTCGGACGGGATGTTTGAGCATTCACAGTTGTTTGGAGGAACATGGCCGTGGGCTTATGCAGCTTTGTGCTTCTCATGTGGTTATTTTGCATATGATCAGTGGGATATGCTGCAATACCGATTATACAGTGGCTGGATCCCTGCCATCTTGGTTCATCATCTGGTTCTCCTGATTTGCTTTACACTTGCTTTGTATAGGAATGTCACCATCAATTATCTCATTCTCACTCTCATTTGCGAGGTATGCATTAGTTTCTTCTTGCAAGATGTGCCTTATGAATAGCTGCTTTCTTTCTTTTTGTTTGTGGTTCTTTCTGGGTCTTTGCATCTCCGTTACCTTCATTGATATGGATCACGACGATGAAGGGTTTAATCACTTTGACATAGACACAAACATGAATTCCGAGTATTTTGCAAGCTTATCTGATAAGTCGTTTTTCAAAGAAACGTAATAGATAGATACTTTATCTAGTGTTGTTGGCTTGAACCGTCCTCATTCTCTTGTGGCACCTACTTTCTTTTTCTGACTTCTTTTTATAGCACTTTCTCCCACTAACTTCTCTTTCCATTCACGTTTTCACGTTGATCTCCCTCTTCACACAGTTTCTATCACTTTACACTCTGTCTTAGTTAACCATTCTCTTACTAGCTCTCTCCATGTGTAGACTTCTCATGACTAGTCTCTCTTTGTATATATCTTCGGTTATGAATCTATTTCTACACAATTTGTGAGATTCCACGTTGGAGAGGAGAACAAATCATTTTTATAAGAGTGTGGAAACCTCTATCCTTAGCAGACGCGTTTTAAAACTTTGAGGGGAAGCTCAGAAGGGAAAGCCTAAAGATGACAATATCTGCTAGCGGTGGGCTTGAGCTGTTATTATGGTATCAAAGTCAGACACCAGACGATGTGCTAGCGAGGATGCTGAATCTCGAAGGGGGGAGGACACCAGGTGGTGTGCCACCACCGAGGACGTTGGGCACCTAGGGGGGTGGATTGGGGGTCCCACATTGATTGGAGAAGAGAACGAGTGCCAGCGAGGACGTTGGGCCCCGAAGCCGAGGGGGGTGGATTGTGAGATCCCACATCTATTGGAGAGCGGAACGAAACATTCTTTATAAGGGTGTGGAAACCTCTCCCTGGCATACCGGTTTTAAAACCTTGGGCTGTTACACAACTTCTCCTACTAAGGTCACTCTACACACCTCTCACTAATTTTCTTTATTAATTTATTGATATGGAGATGCACACACATACACCCATATGTAATGCTCAAATCAAAGAGCATGCCTTCTTTGGGGTAAAAAACAGTCATCTTAGTTAGCAACTGCAAGATTAGAGCTTGTAGTTTCTTTGCACGTTTGGAAGGACTCTGGAAGCCAATCACATCTATTCTTAGAATCAAATCAAGTTTTCATGTTAAATTTGACTTCCAGCTTTTGATCTGCAAAACTGAAACAAGAATCATTGTGATATTTCAGCTGCATTCTATCTTCCTCCACGTAAGGCGATTGCGACGGATGGCTGGTGTTCGTGACGCCGAGAGCTTTATCGTGAAAGTCGAATGGACTCTGAACTGGCTAACGTTCACTTTCGCAAGGTTTGTACCTCACATTCTCATTACTGCTAAGCTCATCATGGATGCTTCCAAGTTTGATAAAGGCGTAGAGCTGCCGCTTGCACTGTTTGGGATGGCTGCCATGAACTTGCTGAATGTTTTTCTTGGCATTGATCTCTTCAACGCTGTAAAGAAAGAGAGTAATTATCAGAAAAATGATCATCTTCATCATGAATGAAGGCCAACATGGTGGAAATTGTATTTGTTCTTTGTATTATATTGTAAGAAAATGCTGAACAGAAAACGGTTCAGGATAAATTTATGTAACACTGAAGACAAATTTGTGTAAAATCAGTTTAATATTTAGTTAAAGAAATTTAGTACTA

mRNA sequence

CAATTCTCGTTTTCACCAGAAGATACAGAACAAGCGATTGAGCTCCATAGCGAATTAATGGCGGGGCGGACGGTGTTGAAGGAGAAGAGCAGGGCAGGAAGCTTCTTCTCCGCGACATTAGTGCTTTGGACGGTCTCTCTTTGGTTCGAAATTCTGTTCGACAGGCGCTTCGAGCTGCTCTACCTCGTATTCGGAGCTCTGTTCTACCAATCCGCCAATTCGGCCATTCGATTTCTTATTTCTAAGGAACCTCTTGTAGTCAACACCGCCGTCTCTCTCCTTCACTCTATTATCACTTCTGCTTCAGTGTTGTTTGTTTTGGCAAATCGGTGGTTGAGTCATGGTTCGGACGGGATGTTTGAGCATTCACAGTTGTTTGGAGGAACATGGCCGTGGGCTTATGCAGCTTTGTGCTTCTCATGTGGTTATTTTGCATATGATCAGTGGGATATGCTGCAATACCGATTATACAGTGGCTGGATCCCTGCCATCTTGGTTCATCATCTGGTTCTCCTGATTTGCTTTACACTTGCTTTGTATAGGAATGTCACCATCAATTATCTCATTCTCACTCTCATTTGCGAGCTGCATTCTATCTTCCTCCACGTAAGGCGATTGCGACGGATGGCTGGTGTTCGTGACGCCGAGAGCTTTATCGTGAAAGTCGAATGGACTCTGAACTGGCTAACGTTCACTTTCGCAAGGTTTGTACCTCACATTCTCATTACTGCTAAGCTCATCATGGATGCTTCCAAGTTTGATAAAGGCGTAGAGCTGCCGCTTGCACTGTTTGGGATGGCTGCCATGAACTTGCTGAATGTTTTTCTTGGCATTGATCTCTTCAACGCTGTAAAGAAAGAGAGTAATTATCAGAAAAATGATCATCTTCATCATGAATGAAGGCCAACATGGTGGAAATTGTATTTGTTCTTTGTATTATATTGTAAGAAAATGCTGAACAGAAAACGGTTCAGGATAAATTTATGTAACACTGAAGACAAATTTGTGTAAAATCAGTTTAATATTTAGTTAAAGAAATTTAGTACTA

Coding sequence (CDS)

ATGGCGGGGCGGACGGTGTTGAAGGAGAAGAGCAGGGCAGGAAGCTTCTTCTCCGCGACATTAGTGCTTTGGACGGTCTCTCTTTGGTTCGAAATTCTGTTCGACAGGCGCTTCGAGCTGCTCTACCTCGTATTCGGAGCTCTGTTCTACCAATCCGCCAATTCGGCCATTCGATTTCTTATTTCTAAGGAACCTCTTGTAGTCAACACCGCCGTCTCTCTCCTTCACTCTATTATCACTTCTGCTTCAGTGTTGTTTGTTTTGGCAAATCGGTGGTTGAGTCATGGTTCGGACGGGATGTTTGAGCATTCACAGTTGTTTGGAGGAACATGGCCGTGGGCTTATGCAGCTTTGTGCTTCTCATGTGGTTATTTTGCATATGATCAGTGGGATATGCTGCAATACCGATTATACAGTGGCTGGATCCCTGCCATCTTGGTTCATCATCTGGTTCTCCTGATTTGCTTTACACTTGCTTTGTATAGGAATGTCACCATCAATTATCTCATTCTCACTCTCATTTGCGAGCTGCATTCTATCTTCCTCCACGTAAGGCGATTGCGACGGATGGCTGGTGTTCGTGACGCCGAGAGCTTTATCGTGAAAGTCGAATGGACTCTGAACTGGCTAACGTTCACTTTCGCAAGGTTTGTACCTCACATTCTCATTACTGCTAAGCTCATCATGGATGCTTCCAAGTTTGATAAAGGCGTAGAGCTGCCGCTTGCACTGTTTGGGATGGCTGCCATGAACTTGCTGAATGTTTTTCTTGGCATTGATCTCTTCAACGCTGTAAAGAAAGAGAGTAATTATCAGAAAAATGATCATCTTCATCATGAATGA

Protein sequence

MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFLISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCFSCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSIFLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVELPLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE

Homology

[Close]

BLAST of CmoCh15G006910 vs. ExPASy Swiss-Prot
Match: A8WGS4 (TLC domain-containing protein 2 OS=Danio rerio OX=7955 GN=tlcd2 PE=2 SV=1)

HSP 1 Score: 56.2 bits (134), Expect = 6.8e-07
Identity = 50/190 (26.32%), Postives = 94/190 (49.47%), Query Frame = 0


Query: 69  NTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCFSCGYFAYD 128
           N + S +HS+IT   V  VL        ++ + E   +F      ++A +  S GYF YD
Sbjct: 42  NISTSFVHSLIT--GVWSVLCFCMHPQMAEDLIETHSVF------SHALVSVSIGYFIYD 101

Query: 129 QWDM-LQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSIFLHVRRL 188
             DM +  ++   W   +L HH+V++ CF +++     + + ++ L+ E++S+FLH+R++
Sbjct: 102 FLDMVINQKIIHSW--ELLFHHVVVITCFGISVLTCRYVGFAVVALLVEINSVFLHLRQV 161

Query: 189 RRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVELPLALFGM 248
            RMA +  A+S   +V   +N  T+   R      +T  L+++           +   G+
Sbjct: 162 LRMANL--AKSTFYRVNSMINLGTYVVFRINTLAWMTRWLVLNRDLIPL-FSYTIGSVGL 218

Query: 249 AAMNLLNVFL 258
           A M  +N+ L
Sbjct: 222 AIMTAMNIVL 218

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BLAST of CmoCh15G006910 vs. ExPASy Swiss-Prot
Match: A6NGC4 (TLC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TLCD2 PE=3 SV=3)

HSP 1 Score: 49.7 bits (117), Expect = 6.3e-05
Identity = 54/197 (27.41%), Postives = 92/197 (46.70%), Query Frame = 0


Query: 69  NTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCFSCGYFAYD 128
           N  VSL HS+++    L  L + +    +D +  H +       WA   +  S GYF  D
Sbjct: 41  NLCVSLAHSLLSGTGALLGL-SLYPQMAADPIHGHPR-------WALVLVAVSVGYFLAD 100

Query: 129 QWDML-QYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSIFLHVRRL 188
             D+L    L   W   +L HHLV++ C + A+     + + +++L+ EL+S  LH+R+L
Sbjct: 101 GADLLWNQTLGKTW--DLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKL 160

Query: 189 RRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVELPLAL--- 248
             ++  R A S    V    +  T    R VP   ++  L      F +  ++PLAL   
Sbjct: 161 LLLS--RQAPSLAFSVTSWASLATLALFRLVPLGWMSLWL------FRQHHQVPLALVTL 219

Query: 249 --FGMAAMNLLNVFLGI 260
              G+  + ++++ LGI
Sbjct: 221 GGIGLVTVGIMSIILGI 219

[Close]

BLAST of CmoCh15G006910 vs. ExPASy Swiss-Prot
Match: Q8VC26 (TLC domain-containing protein 2 OS=Mus musculus OX=10090 GN=Tlcd2 PE=2 SV=1)

HSP 1 Score: 48.9 bits (115), Expect = 1.1e-04
Identity = 45/152 (29.61%), Postives = 74/152 (48.68%), Query Frame = 0


Query: 69  NTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCFSCGYFAYD 128
           N  VSL+HS+++    L  L  ++    +D + +H        PWA   +  S GYFA D
Sbjct: 40  NIFVSLIHSLLSGVGALVGLW-QFPQMVTDPINDHP-------PWARVLVAVSVGYFAAD 99

Query: 129 QWDML-QYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSIFLHVRRL 188
             DML    L   W   +L HHL ++ C + A+     + + +++L+ EL+SI LH+R+L
Sbjct: 100 GVDMLWNQTLAQAW--DLLCHHLAVVSCLSTAVVSGHYVGFSMVSLLLELNSICLHLRKL 159

Query: 189 RRMAGVRDAESFIVKVEWTLNWLTFTFARFVP 220
             ++    A S   +V    +  T    R +P
Sbjct: 160 LLLS--HKAPSLAFRVSSWASLATLVLFRLLP 179

[Close]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL
Match: A0A6J1FID3 (TLC domain-containing protein 2 OS=Cucurbita moschata OX=3662 GN=LOC111445599 PE=4 SV=1)

HSP 1 Score: 551.6 bits (1420), Expect = 1.9e-153
Identity = 280/280 (100.00%), Postives = 280/280 (100.00%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL
Sbjct: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF
Sbjct: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL
Sbjct: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE
Sbjct: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 280

[Close]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL
Match: A0A6J1K0R9 (TLC domain-containing protein 2 OS=Cucurbita maxima OX=3661 GN=LOC111489133 PE=4 SV=1)

HSP 1 Score: 542.0 bits (1395), Expect = 1.5e-150
Identity = 274/280 (97.86%), Postives = 276/280 (98.57%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRTVLKE+SRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL
Sbjct: 1   MAGRTVLKEESRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           ISKEPLVVNTAVSLLHSIITSASVLF+L NRWLSHG DGMFEHSQLFGGTWPWAYAALCF
Sbjct: 61  ISKEPLVVNTAVSLLHSIITSASVLFILVNRWLSHGLDGMFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTF FARFVPHILITAKLIMDASKFDKGVEL
Sbjct: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFIFARFVPHILITAKLIMDASKFDKGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDH HHE
Sbjct: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHFHHE 280

[Close]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL
Match: A0A0A0KH54 (TLC domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_6G385110 PE=4 SV=1)

HSP 1 Score: 483.0 bits (1242), Expect = 8.3e-133
Identity = 245/282 (86.88%), Postives = 262/282 (92.91%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRT+LKEKSRA SFFSATL+LW+VSLWFEILFDRRF LLY+VFGALFYQSANS+IR L
Sbjct: 1   MAGRTLLKEKSRAWSFFSATLLLWSVSLWFEILFDRRFRLLYVVFGALFYQSANSSIRLL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSH--GSDGMFEHSQLFGGTWPWAYAAL 120
           +SK+PL+VNT+VSLLHSIITSASVLFVL NRWLS+  GS+GMFEHSQLFGGTWPWA+AAL
Sbjct: 61  LSKDPLLVNTSVSLLHSIITSASVLFVLVNRWLSYGSGSEGMFEHSQLFGGTWPWAFAAL 120

Query: 121 CFSCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELH 180
           CFSCGYFAYDQWDML+Y LYSGWIPAILVHHLVLLICFTLALYRNVTINYL LTLICE+H
Sbjct: 121 CFSCGYFAYDQWDMLRYGLYSGWIPAILVHHLVLLICFTLALYRNVTINYLNLTLICEMH 180

Query: 181 SIFLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGV 240
           SIFLHVRRLRRMAGVRDA+S IVKVEW LNWLTF FARFVPHILIT KLI+DASKFDKGV
Sbjct: 181 SIFLHVRRLRRMAGVRDAKSIIVKVEWILNWLTFVFARFVPHILITVKLIIDASKFDKGV 240

Query: 241 ELPLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           ELPLAL GMA MNLLN  LGIDL NAVKKESNY+K D  HHE
Sbjct: 241 ELPLALSGMAGMNLLNALLGIDLLNAVKKESNYKKTDDTHHE 282

[Close]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL
Match: A0A1S3CRX5 (TLC domain-containing protein 2 OS=Cucumis melo OX=3656 GN=LOC103504058 PE=4 SV=1)

HSP 1 Score: 482.3 bits (1240), Expect = 1.4e-132
Identity = 242/282 (85.82%), Postives = 261/282 (92.55%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRT+LKEKSRAGSFFSATL+LW+VSLWFEILFDRRF LLY+VFGALFYQSANS+IR L
Sbjct: 1   MAGRTLLKEKSRAGSFFSATLLLWSVSLWFEILFDRRFRLLYVVFGALFYQSANSSIRVL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSH--GSDGMFEHSQLFGGTWPWAYAAL 120
           +SK+PL+VNT+VSLLHSI+TSASVLFVL NRWLS+   S+GMFEHSQLFGGTWPWAYAAL
Sbjct: 61  VSKDPLLVNTSVSLLHSIVTSASVLFVLVNRWLSYDSSSEGMFEHSQLFGGTWPWAYAAL 120

Query: 121 CFSCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELH 180
           CFSCGYFAYDQWDML+Y LYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTL+CE+H
Sbjct: 121 CFSCGYFAYDQWDMLRYGLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLVCEMH 180

Query: 181 SIFLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGV 240
           SIFLHVRRLRRMAGVRDA+S IVKVEW LNWLTF FARFVPHILIT KLI+DA KFDKGV
Sbjct: 181 SIFLHVRRLRRMAGVRDAKSIIVKVEWILNWLTFVFARFVPHILITVKLIIDAYKFDKGV 240

Query: 241 ELPLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           ELPLAL GM  MNLLN  LGIDL NAV+KESNY+K D  HHE
Sbjct: 241 ELPLALSGMTGMNLLNALLGIDLLNAVRKESNYKKTDDTHHE 282

[Close]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL
Match: A0A6J1CKF5 (TLC domain-containing protein 2 isoform X2 OS=Momordica charantia OX=3673 GN=LOC111011955 PE=4 SV=1)

HSP 1 Score: 459.9 bits (1182), Expect = 7.5e-126
Identity = 235/280 (83.93%), Postives = 251/280 (89.64%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGR V KEKSRAGSFFSATLVLW VS+WFEILF RR ELLY+VFGALFYQSAN  +R L
Sbjct: 1   MAGRRVPKEKSRAGSFFSATLVLWIVSIWFEILFYRRSELLYVVFGALFYQSANWTVRAL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           +SK+PL VNT+VSLLHS ITSASVLF+L ++WLS+GS GMFEHSQL GGTW  AYAALCF
Sbjct: 61  VSKDPLFVNTSVSLLHSTITSASVLFILVSQWLSYGSHGMFEHSQLVGGTWSGAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDML Y+LYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLLYQLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDA+S +VKVEW LNWLTF FAR VPHILITAKL++DASKFD+GVEL
Sbjct: 181 FLHVRRLRRMAGVRDAKSIVVKVEWILNWLTFVFARVVPHILITAKLVVDASKFDRGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLAL GMA MNLLN FLGIDL NAVKKES YQK DH   E
Sbjct: 241 PLALSGMAGMNLLNAFLGIDLINAVKKESKYQKRDHPRRE 280

[Close]

BLAST of CmoCh15G006910 vs. NCBI nr
Match: XP_022939854.1 (TLC domain-containing protein 2 [Cucurbita moschata] >KAG6578966.1 TLC domain-containing protein 2, partial [Cucurbita argyrosperma subsp. sororia] >KAG7016488.1 TLC domain-containing protein 2 [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 551.6 bits (1420), Expect = 3.9e-153
Identity = 280/280 (100.00%), Postives = 280/280 (100.00%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL
Sbjct: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF
Sbjct: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL
Sbjct: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE
Sbjct: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 280

[Close]

BLAST of CmoCh15G006910 vs. NCBI nr
Match: XP_023550889.1 (TLC domain-containing protein 2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 543.9 bits (1400), Expect = 8.2e-151
Identity = 276/280 (98.57%), Postives = 278/280 (99.29%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRT+LKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL
Sbjct: 1   MAGRTMLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           ISKEPLVVNTAVSLLHSIITSASVLFVL NRWLSHGSDGMFEHSQLFGGTWPWAYAALCF
Sbjct: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLVNRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTF FARFVPHILITAKLIMDASKFDKGVEL
Sbjct: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFIFARFVPHILITAKLIMDASKFDKGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLH+E
Sbjct: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHNE 280

[Close]

BLAST of CmoCh15G006910 vs. NCBI nr
Match: XP_022992953.1 (TLC domain-containing protein 2 [Cucurbita maxima])

HSP 1 Score: 542.0 bits (1395), Expect = 3.1e-150
Identity = 274/280 (97.86%), Postives = 276/280 (98.57%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRTVLKE+SRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL
Sbjct: 1   MAGRTVLKEESRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           ISKEPLVVNTAVSLLHSIITSASVLF+L NRWLSHG DGMFEHSQLFGGTWPWAYAALCF
Sbjct: 61  ISKEPLVVNTAVSLLHSIITSASVLFILVNRWLSHGLDGMFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI
Sbjct: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTF FARFVPHILITAKLIMDASKFDKGVEL
Sbjct: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFIFARFVPHILITAKLIMDASKFDKGVEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDH HHE
Sbjct: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHFHHE 280

[Close]

BLAST of CmoCh15G006910 vs. NCBI nr
Match: XP_038884583.1 (TLC domain-containing protein 2 [Benincasa hispida])

HSP 1 Score: 494.2 bits (1271), Expect = 7.4e-136
Identity = 249/280 (88.93%), Postives = 264/280 (94.29%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRTVLKEK RAGSFFSATLVLW+VSL FEILFDRRFELLY+VFGALFYQSANSAIRFL
Sbjct: 1   MAGRTVLKEKRRAGSFFSATLVLWSVSLCFEILFDRRFELLYVVFGALFYQSANSAIRFL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCF 120
           +SK+PL+VNT+VSLLHS ITSASVLFVL NRWLS+GS+G+FEHSQLFGGTWPWAYAALCF
Sbjct: 61  VSKDPLLVNTSVSLLHSTITSASVLFVLVNRWLSYGSEGIFEHSQLFGGTWPWAYAALCF 120

Query: 121 SCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSI 180
           SCGYFAYDQWDMLQY LYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICE+HSI
Sbjct: 121 SCGYFAYDQWDMLQYGLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICEMHSI 180

Query: 181 FLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVEL 240
           FLHVRRLRRMAGVRDA+S IVKVEW LNWLTF FARFVPHILITAKLIMDASKFDKG+EL
Sbjct: 181 FLHVRRLRRMAGVRDAKSVIVKVEWILNWLTFVFARFVPHILITAKLIMDASKFDKGIEL 240

Query: 241 PLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           PLAL GMA MNLLN  LG+DL +AV+KES YQK DH HHE
Sbjct: 241 PLALSGMAGMNLLNALLGMDLLSAVRKESYYQKTDHSHHE 280

[Close]

BLAST of CmoCh15G006910 vs. NCBI nr
Match: XP_004150440.1 (TLC domain-containing protein 2 [Cucumis sativus] >KGN47727.1 hypothetical protein Csa_018230 [Cucumis sativus])

HSP 1 Score: 483.0 bits (1242), Expect = 1.7e-132
Identity = 245/282 (86.88%), Postives = 262/282 (92.91%), Query Frame = 0


Query: 1   MAGRTVLKEKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFL 60
           MAGRT+LKEKSRA SFFSATL+LW+VSLWFEILFDRRF LLY+VFGALFYQSANS+IR L
Sbjct: 1   MAGRTLLKEKSRAWSFFSATLLLWSVSLWFEILFDRRFRLLYVVFGALFYQSANSSIRLL 60

Query: 61  ISKEPLVVNTAVSLLHSIITSASVLFVLANRWLSH--GSDGMFEHSQLFGGTWPWAYAAL 120
           +SK+PL+VNT+VSLLHSIITSASVLFVL NRWLS+  GS+GMFEHSQLFGGTWPWA+AAL
Sbjct: 61  LSKDPLLVNTSVSLLHSIITSASVLFVLVNRWLSYGSGSEGMFEHSQLFGGTWPWAFAAL 120

Query: 121 CFSCGYFAYDQWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELH 180
           CFSCGYFAYDQWDML+Y LYSGWIPAILVHHLVLLICFTLALYRNVTINYL LTLICE+H
Sbjct: 121 CFSCGYFAYDQWDMLRYGLYSGWIPAILVHHLVLLICFTLALYRNVTINYLNLTLICEMH 180

Query: 181 SIFLHVRRLRRMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGV 240
           SIFLHVRRLRRMAGVRDA+S IVKVEW LNWLTF FARFVPHILIT KLI+DASKFDKGV
Sbjct: 181 SIFLHVRRLRRMAGVRDAKSIIVKVEWILNWLTFVFARFVPHILITVKLIIDASKFDKGV 240

Query: 241 ELPLALFGMAAMNLLNVFLGIDLFNAVKKESNYQKNDHLHHE 281
           ELPLAL GMA MNLLN  LGIDL NAVKKESNY+K D  HHE
Sbjct: 241 ELPLALSGMAGMNLLNALLGIDLLNAVKKESNYKKTDDTHHE 282

[Close]

BLAST of CmoCh15G006910 vs. TAIR 10
Match: AT1G21790.1 (TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein )

HSP 1 Score: 370.2 bits (949), Expect = 1.5e-102
Identity = 187/273 (68.50%), Postives = 226/273 (82.78%), Query Frame = 0


Query: 9   EKSRAGSFFSATLVLWTVSLWFEILFDRRFELLYLVFGALFYQSANSAIRFLISKEPLVV 68
           +K+ AG FF ATL+LW VS+ FEI F+ R ELL+++ G  F+Q  N  +R  IS++P+ V
Sbjct: 12  KKNGAGQFFLATLLLWLVSVVFEIAFNLRTELLWVICGGCFFQLMNWVVRSWISRDPIFV 71

Query: 69  NTAVSLLHSIITSASVLFVLANRWLSHGSDGMFEHSQLFGGTWPWAYAALCFSCGYFAYD 128
           NT+VSLLHSIITSASV+F+L N+ L+ G D MF+HS+L GGTW WAY ALCFSCGYFAYD
Sbjct: 72  NTSVSLLHSIITSASVVFILLNQCLAKGLDEMFDHSELVGGTWKWAYPALCFSCGYFAYD 131

Query: 129 QWDMLQYRLYSGWIPAILVHHLVLLICFTLALYRNVTINYLILTLICELHSIFLHVRRLR 188
           QWDMLQYRLYSG IP+ILVHHLVLL+CFTLALYRNVTINYLILTLICE+HSIFLHVR+LR
Sbjct: 132 QWDMLQYRLYSGLIPSILVHHLVLLVCFTLALYRNVTINYLILTLICEMHSIFLHVRKLR 191

Query: 189 RMAGVRDAESFIVKVEWTLNWLTFTFARFVPHILITAKLIMDASKFDKGVELPLALFGMA 248
           RMAG+RD+ + +VK+EW LNW  F FAR +PHILIT KLI DA KF KGVELPLAL GMA
Sbjct: 192 RMAGIRDSNTALVKLEWVLNWTAFVFARCIPHILITIKLIKDAHKFGKGVELPLALSGMA 251

Query: 249 AMNLLNVFLGIDLFNAVKKESNY---QKNDHLH 279
            MN+LNV LG+DLF+A ++E ++   Q+N +LH
Sbjct: 252 GMNILNVGLGLDLFHAFRRERSHRRNQENGNLH 284

The following BLAST results are available for this feature:

BLAST of CmoCh15G006910 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
A8WGS4	6.8e-07	26.32	TLC domain-containing protein 2 OS=Danio rerio OX=7955 GN=tlcd2 PE=2 SV=1	[more]
A6NGC4	6.3e-05	27.41	TLC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TLCD2 PE=3 SV=3	[more]
Q8VC26	1.1e-04	29.61	TLC domain-containing protein 2 OS=Mus musculus OX=10090 GN=Tlcd2 PE=2 SV=1	[more]

BLAST of CmoCh15G006910 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1FID3	1.9e-153	100.00	TLC domain-containing protein 2 OS=Cucurbita moschata OX=3662 GN=LOC111445599 PE...	[more]
A0A6J1K0R9	1.5e-150	97.86	TLC domain-containing protein 2 OS=Cucurbita maxima OX=3661 GN=LOC111489133 PE=4...	[more]
A0A0A0KH54	8.3e-133	86.88	TLC domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_6G385110 PE=4 SV...	[more]
A0A1S3CRX5	1.4e-132	85.82	TLC domain-containing protein 2 OS=Cucumis melo OX=3656 GN=LOC103504058 PE=4 SV=...	[more]
A0A6J1CKF5	7.5e-126	83.93	TLC domain-containing protein 2 isoform X2 OS=Momordica charantia OX=3673 GN=LOC...	[more]

BLAST of CmoCh15G006910 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022939854.1	3.9e-153	100.00	TLC domain-containing protein 2 [Cucurbita moschata] >KAG6578966.1 TLC domain-co...	[more]
XP_023550889.1	8.2e-151	98.57	TLC domain-containing protein 2 [Cucurbita pepo subsp. pepo]	[more]
XP_022992953.1	3.1e-150	97.86	TLC domain-containing protein 2 [Cucurbita maxima]	[more]
XP_038884583.1	7.4e-136	88.93	TLC domain-containing protein 2 [Benincasa hispida]	[more]
XP_004150440.1	1.7e-132	86.88	TLC domain-containing protein 2 [Cucumis sativus] >KGN47727.1 hypothetical prote...	[more]

BLAST of CmoCh15G006910 vs. TAIR 10


Match Name	E-value	Identity	Description
AT1G21790.1	1.5e-102	68.50	TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein	[more]

InterPro

Analysis Name: InterPro Annotations of Cucurbita moschata (Rifu) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006634	TRAM/LAG1/CLN8 homology domain	SMART	SM00724	lag1_27	coord: 62..269 e-value: 5.6E-29 score: 112.3
IPR006634	TRAM/LAG1/CLN8 homology domain	PFAM	PF03798	TRAM_LAG1_CLN8	coord: 69..258 e-value: 5.5E-18 score: 65.4
IPR006634	TRAM/LAG1/CLN8 homology domain	PROSITE	PS50922	TLC	coord: 62..270 score: 14.600731
None	No IPR available	PANTHER	PTHR13439:SF4	TLC DOMAIN-CONTAINING PROTEIN FLD-1	coord: 16..275
None	No IPR available	PANTHER	PTHR13439	CT120 PROTEIN	coord: 16..275

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CmoCh15G006910.1	CmoCh15G006910.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0071709	membrane assembly
biological_process	GO:0055091	phospholipid homeostasis
biological_process	GO:0007009	plasma membrane organization
biological_process	GO:0097035	regulation of membrane lipid distribution
cellular_component	GO:0016021	integral component of membrane
cellular_component	GO:0005886	plasma membrane