CmoCh12G005920 (gene) Cucurbita moschata (Rifu) v1

Overview
NameCmoCh12G005920
Typegene
OrganismCucurbita moschata (Cucurbita moschata (Rifu) v1)
DescriptionTP53-regulated inhibitor of apoptosis 1
LocationCmo_Chr12: 3629320 .. 3631836 (+)
RNA-Seq ExpressionCmoCh12G005920
SyntenyCmoCh12G005920
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptidethree_prime_UTR
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGAATGGGAAGGGAAAGTATATGCAGCATTCCGGACGTCTTGGCTCGACGTATTTGTTATAAGCTCGAGTCTTGACGAGTTTCTGGCAATGTAAATCCCTGCTGCTGCTGCTGCTGCTGCTACAATGTGATAGAATAGGTGAAAGAAAGAAACTGGGAGACAGTTCCACGCTTATGGTGTATTTGATTCGTGTATCATTTCGTACTCTTGGTGCTTATGATAAAGAGTTAGCAGAAATTAAGGTTGTTGTATGCTACTTGCTTTCAAAGTTCTAAATATTTTGGGTATTCCGATGTTTTTCAGCTGAACTCGAGCTTGGTTGACCTGAAAAAACGTTAATTTAACAGCGGGAAGGGGGCGGACTTTCCTATGGTAGTCCCGCTACGGCTATGACCGTTCGTCCCGTCTCATCTTTCTTTGGCTATGGGTCGTCTGAGGTGAAATGGATTAATTTAATGTGTATTTTGTTTGTTAAATTTGATAATGAAATCAAATCAATATATAATTGGGTATTGAAAATTAACGTAAATGATGTAAATTTTGAAGCAAAGAAGGAAAATGAGCGTTGAATTGAAATGAGAATGTTATAGAAGGCGCGAGGACACGAAGCGATTTCGTTGGCTCAGAAATTTACAAAAACCGCCGCTTCTTCTCCGGCGGCCATTTTGATGGAGTGGTAAAATCTCAATCAATGGGCATCAAGCGAGAGAGTAAAAGGTCGGCTTCTGCAACTTCGCCGTGTGCTGATCTTAGGGCTGTATATCACAATTGTTTCAATCGGTATGTTTCCATTTTCATTCCCTAAACCCTTTCTGAACCCTAATTAAGCGATTTCTGGTTTTGATTCGCAGTTGGTACTCGGAGAAGTTTGTGAAAGGTCAATTCGATGAAGAACCCTGCGTCTCCGAATGGCAGAAGTACAGAGCTTGCCTCTCTGTATGTCTTCGAGCTTTGTTTGATTCCTTCCTATTAGGTTTTGTCAATGTCGTTTGATTTCGTTGCGATCTGATATAGCCTCCAAATTACAGGAGCATTTGGAAGATAAGAAGCTGAAGCGCTTCTTGGAAGAGGAAACGATTGTTCATTCCTCCATGAAAGCTGAAACGAGTTGAGAATCGAGATTGGCTTACTTGAATGGACATTTTGAGGTCTTCACAAACTTGAAAACCATGTTTAATTGTTATTTTCCACCACTGTGTTAGAACAAATGGAGTTTTTTTGCTGCTCAAACTCTAGTTTATTTGAAAAGCATCTGAACTTTAGCTACATGATAGAAATTCAACTAGATCAGCTTATTAAGAAGATACGTGGTCTTGTTTAATAGAAAAGTTCCTGTGTTCTATGGTGAGTTCTTCTTCTTTTCTCTGCATATTTCACTTCCCTCAGCAGTAATCCTGCAGCCCACTTAGGCGAGCCATTGTTACAGAACCAAAAGAGTTTGTTCTTTTCTTTTCTAGTTTTTTTTGGCCAATTCACGTCCCGTAGAAGCTCATTATTTTTAATTTTTAGCTTCTATAATAATTGTGTGAGATCCCACGTCGGTTGGAGAGAGGAACGAAACATTCCTCAGAAAGGTGTAGAAACCTCTCCTTAGTAGACGCGCTCCCTGGTAGACGCACTTTAAAATCTTGAGGAAAAGCCCATAAGGGAAATCCTAAAGAGGACGATATTTGCTAGCGGTGTGCTTGAGCGGTTACAAATGGTATCAGAGCTAGACACCGAGCGGTGTGCTAGCGAGGACGCTGGTCCCCAAGGGGTGGATTGTGAGATCCCACGTCGGTTGGAGAGGAGAATGAAGCATTTCTTATAAGGGCGTGGAAACCTCTCCTAAATAGACGCATTTTAAAACCTTAGAGAATGAAGCATTTCTTATAAGGGCGTGGAAACCTCTTCTAAATAGACGCATTTTAAAACCTTAGAGAATGAAGCATTTCTTGTAAGGGCGTGGAAACCTCTCCTAAATAGATGCATTTTAAAACTTTAGAGGGAAGTTTAAAGAGGACAATATCGACTAACGGTGAGCTTAAACTATTATAAGTTCTGCTCTTCTTATCTGTTCAAGAAAATTGCAGAAGATTGGGTGGTTGGTATCTGCTGTATGATACCTCTTTTGAAGAAACTATTGATGTCAGACATGAGAATGTGGCACAGTGGAGCATTATGCTGGTAGTGAGCTGCATTCATTTGCACCATTTCAGAGTCAAAGTGCAAAGTGAACATGAGGATCATTGAAGGTGCAATCACATTCAAGGTGCACTCTCTCTATCATCTGATTTAAAGACCATTCATGCTTTGATTGCTATTGGGAAACTTTTCCTGTCATTGAAATGCTAAATTTTGCCTTTGTTTTACGCTCTCTTTTGGAAATGCAACCCATTTGGTATATTTGAATTATACTATAAGATAGATTTGTAGTCATGAATAACATTGAATTTGGATATTGGATAGTCCTGTACTATTATGTTTGGCTTTGAAGTTGAAAGCTTAAATTTGGATAGTCCTCTCGTCAGCTTAAG

mRNA sequence

ATGAATGGGAAGGGAAATTTCTGGCAATGTAAATCCCTGCTGCTGCTGCTGCTGCTGCTACAATGTGATAGAATAGGTGAAAGAAAGAAACTGGGAGACAGTTCCACGCTTATGGTGTATTTGATTCGTGTATCATTTCGTACTCTTGGTGCTTATGATAAAGAGTTAGCAGAAATTAAGCGGGAAGGGGGCGGACTTTCCTATGGTAGTCCCGCTACGGCTATGACCGTTCGTCCCGTCTCATCTTTCTTTGGCTATGGGTCGTCTGAGGTGAAATGGATTAATTTAATGTGCGCGAGGACACGAAGCGATTTCGTTGGCTCAGAAATTTACAAAAACCGCCGCTTCTTCTCCGGCGGCCATTTTGATGGAGTGGTAAAATCTCAATCAATGGGCATCAAGCGAGAGAGTAAAAGGTCGGCTTCTGCAACTTCGCCGTGTGCTGATCTTAGGGCTGTATATCACAATTGTTTCAATCGTTGGTACTCGGAGAAGTTTGTGAAAGGTCAATTCGATGAAGAACCCTGCGTCTCCGAATGGCAGAAGTACAGAGCTTGCCTCTCTGAGCATTTGGAAGATAAGAAGCTGAAGCGCTTCTTGGAAGAGGAAACGATTGTTCATTCCTCCATGAAAGCTGAAACGAGTTGAGAATCGAGATTGGCTTACTTGAATGGACATTTTGAGAAGATTGGGTGGTTGGTATCTGCTGTATGATACCTCTTTTGAAGAAACTATTGATGTCAGACATGAGAATGTGGCACAGTGGAGCATTATGCTGGTAGTGAGCTGCATTCATTTGCACCATTTCAGAGTCAAAGTGCAAAGTGAACATGAGGATCATTGAAGGTGCAATCACATTCAAGGTGCACTCTCTCTATCATCTGATTTAAAGACCATTCATGCTTTGATTGCTATTGGGAAACTTTTCCTGTCATTGAAATGCTAAATTTTGCCTTTGTTTTACGCTCTCTTTTGGAAATGCAACCCATTTGGTATATTTGAATTATACTATAAGATAGATTTGTAGTCATGAATAACATTGAATTTGGATATTGGATAGTCCTGTACTATTATGTTTGGCTTTGAAGTTGAAAGCTTAAATTTGGATAGTCCTCTCGTCAGCTTAAG

Coding sequence (CDS)

ATGAATGGGAAGGGAAATTTCTGGCAATGTAAATCCCTGCTGCTGCTGCTGCTGCTGCTACAATGTGATAGAATAGGTGAAAGAAAGAAACTGGGAGACAGTTCCACGCTTATGGTGTATTTGATTCGTGTATCATTTCGTACTCTTGGTGCTTATGATAAAGAGTTAGCAGAAATTAAGCGGGAAGGGGGCGGACTTTCCTATGGTAGTCCCGCTACGGCTATGACCGTTCGTCCCGTCTCATCTTTCTTTGGCTATGGGTCGTCTGAGGTGAAATGGATTAATTTAATGTGCGCGAGGACACGAAGCGATTTCGTTGGCTCAGAAATTTACAAAAACCGCCGCTTCTTCTCCGGCGGCCATTTTGATGGAGTGGTAAAATCTCAATCAATGGGCATCAAGCGAGAGAGTAAAAGGTCGGCTTCTGCAACTTCGCCGTGTGCTGATCTTAGGGCTGTATATCACAATTGTTTCAATCGTTGGTACTCGGAGAAGTTTGTGAAAGGTCAATTCGATGAAGAACCCTGCGTCTCCGAATGGCAGAAGTACAGAGCTTGCCTCTCTGAGCATTTGGAAGATAAGAAGCTGAAGCGCTTCTTGGAAGAGGAAACGATTGTTCATTCCTCCATGAAAGCTGAAACGAGTTGA

Protein sequence

MNGKGNFWQCKSLLLLLLLLQCDRIGERKKLGDSSTLMVYLIRVSFRTLGAYDKELAEIKREGGGLSYGSPATAMTVRPVSSFFGYGSSEVKWINLMCARTRSDFVGSEIYKNRRFFSGGHFDGVVKSQSMGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLEDKKLKRFLEEETIVHSSMKAETS
Homology
BLAST of CmoCh12G005920 vs. ExPASy Swiss-Prot
Match: Q9SMZ9 (Uncharacterized protein At4g33100 OS=Arabidopsis thaliana OX=3702 GN=At4g33100 PE=3 SV=1)

HSP 1 Score: 105.9 bits (263), Expect = 5.7e-22
Identity = 48/82 (58.54%), Postives = 64/82 (78.05%), Query Frame = 0

Query: 134 KRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLED 193
           K++S  + S+TSPCADLR  YHNCFN+WYSEKFVKGQ+D+E CV+EW+KYR CLSE+L+ 
Sbjct: 6   KKDSTSARSSTSPCADLRNAYHNCFNKWYSEKFVKGQWDKEECVAEWKKYRDCLSENLDG 65

Query: 194 KKLKRFLEEETIVHSSMKAETS 216
           K L R LE +  ++ + +A  S
Sbjct: 66  KLLTRILEVDGELNPTKQATDS 87

BLAST of CmoCh12G005920 vs. ExPASy Swiss-Prot
Match: O60200 (Mitochondrial distribution and morphology protein 35 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MDM35 PE=1 SV=3)

HSP 1 Score: 61.6 bits (148), Expect = 1.2e-08
Identity = 27/63 (42.86%), Postives = 37/63 (58.73%), Query Frame = 0

Query: 140 SASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLEDKKLKRF 199
           SAS    C DL+  Y +CFN WYSEKF+KG+  E  C  +W  Y  C++  L  + +K  
Sbjct: 6   SASFAPECTDLKTKYDSCFNEWYSEKFLKGKSVENECSKQWYAYTTCVNAALVKQGIKPA 65

Query: 200 LEE 203
           L+E
Sbjct: 66  LDE 68

BLAST of CmoCh12G005920 vs. ExPASy Swiss-Prot
Match: A9ULB4 (TP53-regulated inhibitor of apoptosis 1 OS=Xenopus tropicalis OX=8364 GN=triap1 PE=2 SV=1)

HSP 1 Score: 59.3 bits (142), Expect = 6.1e-08
Identity = 21/55 (38.18%), Postives = 36/55 (65.45%), Query Frame = 0

Query: 142 SATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLEDKKL 197
           S    C D++  Y  CFNRW++EKF+KG+   +PC   +++YR C+ + ++DK +
Sbjct: 3   SVGEECTDMKREYDQCFNRWFAEKFLKGECSGDPCTELFRRYRDCVQKAIKDKDI 57

BLAST of CmoCh12G005920 vs. ExPASy Swiss-Prot
Match: Q6DD38 (TP53-regulated inhibitor of apoptosis 1-B OS=Xenopus laevis OX=8355 GN=triap1-b PE=3 SV=1)

HSP 1 Score: 58.5 bits (140), Expect = 1.0e-07
Identity = 21/55 (38.18%), Postives = 35/55 (63.64%), Query Frame = 0

Query: 142 SATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLEDKKL 197
           S    C D++  Y  CFNRW++EKF+KG    +PC   +++YR C+ + ++DK +
Sbjct: 3   SVGEECTDMKREYDQCFNRWFAEKFLKGDGSGDPCTELFRRYRECVQKAIKDKDI 57

BLAST of CmoCh12G005920 vs. ExPASy Swiss-Prot
Match: Q6INR6 (TP53-regulated inhibitor of apoptosis 1-A OS=Xenopus laevis OX=8355 GN=triap1-a PE=3 SV=1)

HSP 1 Score: 57.8 bits (138), Expect = 1.8e-07
Identity = 21/55 (38.18%), Postives = 35/55 (63.64%), Query Frame = 0

Query: 142 SATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLEDKKL 197
           S    C D++  Y  CFNRW++EKF+KG    +PC   +++YR C+ + ++DK +
Sbjct: 3   SVGEECTDMKRDYDQCFNRWFAEKFLKGAGSGDPCTELFRRYRECVQKAIKDKDI 57

BLAST of CmoCh12G005920 vs. ExPASy TrEMBL
Match: A0A6J1GGR4 (uncharacterized protein At4g33100 isoform X2 OS=Cucurbita moschata OX=3662 GN=LOC111454054 PE=3 SV=1)

HSP 1 Score: 178.3 bits (451), Expect = 3.4e-41
Identity = 85/85 (100.00%), Postives = 85/85 (100.00%), Query Frame = 0

Query: 131 MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 190
           MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH
Sbjct: 1   MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 60

Query: 191 LEDKKLKRFLEEETIVHSSMKAETS 216
           LEDKKLKRFLEEETIVHSSMKAETS
Sbjct: 61  LEDKKLKRFLEEETIVHSSMKAETS 85

BLAST of CmoCh12G005920 vs. ExPASy TrEMBL
Match: A0A6J1GHR8 (uncharacterized protein At4g33100 isoform X1 OS=Cucurbita moschata OX=3662 GN=LOC111454054 PE=3 SV=1)

HSP 1 Score: 176.8 bits (447), Expect = 9.8e-41
Identity = 84/84 (100.00%), Postives = 84/84 (100.00%), Query Frame = 0

Query: 131 MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 190
           MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH
Sbjct: 1   MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 60

Query: 191 LEDKKLKRFLEEETIVHSSMKAET 215
           LEDKKLKRFLEEETIVHSSMKAET
Sbjct: 61  LEDKKLKRFLEEETIVHSSMKAET 84

BLAST of CmoCh12G005920 vs. ExPASy TrEMBL
Match: A0A6J1KJX4 (uncharacterized protein At4g33100 isoform X4 OS=Cucurbita maxima OX=3661 GN=LOC111495937 PE=3 SV=1)

HSP 1 Score: 176.0 bits (445), Expect = 1.7e-40
Identity = 84/85 (98.82%), Postives = 84/85 (98.82%), Query Frame = 0

Query: 131 MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 190
           MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQ DEEPCVSEWQKYRACLSEH
Sbjct: 1   MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQLDEEPCVSEWQKYRACLSEH 60

Query: 191 LEDKKLKRFLEEETIVHSSMKAETS 216
           LEDKKLKRFLEEETIVHSSMKAETS
Sbjct: 61  LEDKKLKRFLEEETIVHSSMKAETS 85

BLAST of CmoCh12G005920 vs. ExPASy TrEMBL
Match: A0A6J1KME9 (uncharacterized protein At4g33100 isoform X3 OS=Cucurbita maxima OX=3661 GN=LOC111495937 PE=3 SV=1)

HSP 1 Score: 174.5 bits (441), Expect = 4.8e-40
Identity = 83/84 (98.81%), Postives = 83/84 (98.81%), Query Frame = 0

Query: 131 MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 190
           MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQ DEEPCVSEWQKYRACLSEH
Sbjct: 1   MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQLDEEPCVSEWQKYRACLSEH 60

Query: 191 LEDKKLKRFLEEETIVHSSMKAET 215
           LEDKKLKRFLEEETIVHSSMKAET
Sbjct: 61  LEDKKLKRFLEEETIVHSSMKAET 84

BLAST of CmoCh12G005920 vs. ExPASy TrEMBL
Match: A0A6J1KNW5 (uncharacterized protein At4g33100 isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC111495937 PE=3 SV=1)

HSP 1 Score: 174.5 bits (441), Expect = 4.8e-40
Identity = 83/84 (98.81%), Postives = 83/84 (98.81%), Query Frame = 0

Query: 131 MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEH 190
           MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQ DEEPCVSEWQKYRACLSEH
Sbjct: 1   MGIKRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQLDEEPCVSEWQKYRACLSEH 60

Query: 191 LEDKKLKRFLEEETIVHSSMKAET 215
           LEDKKLKRFLEEETIVHSSMKAET
Sbjct: 61  LEDKKLKRFLEEETIVHSSMKAET 84

BLAST of CmoCh12G005920 vs. TAIR 10
Match: AT4G33100.1 (CONTAINS InterPro DOMAIN/s: Mitochondrial distribution/morphology family 35/apoptosis (InterPro:IPR007918); Has 214 Blast hits to 214 proteins in 102 species: Archae - 0; Bacteria - 0; Metazoa - 110; Fungi - 69; Plants - 29; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink). )

HSP 1 Score: 105.9 bits (263), Expect = 4.1e-23
Identity = 48/82 (58.54%), Postives = 64/82 (78.05%), Query Frame = 0

Query: 134 KRESKRSASATSPCADLRAVYHNCFNRWYSEKFVKGQFDEEPCVSEWQKYRACLSEHLED 193
           K++S  + S+TSPCADLR  YHNCFN+WYSEKFVKGQ+D+E CV+EW+KYR CLSE+L+ 
Sbjct: 6   KKDSTSARSSTSPCADLRNAYHNCFNKWYSEKFVKGQWDKEECVAEWKKYRDCLSENLDG 65

Query: 194 KKLKRFLEEETIVHSSMKAETS 216
           K L R LE +  ++ + +A  S
Sbjct: 66  KLLTRILEVDGELNPTKQATDS 87

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q9SMZ95.7e-2258.54Uncharacterized protein At4g33100 OS=Arabidopsis thaliana OX=3702 GN=At4g33100 P... [more]
O602001.2e-0842.86Mitochondrial distribution and morphology protein 35 OS=Saccharomyces cerevisiae... [more]
A9ULB46.1e-0838.18TP53-regulated inhibitor of apoptosis 1 OS=Xenopus tropicalis OX=8364 GN=triap1 ... [more]
Q6DD381.0e-0738.18TP53-regulated inhibitor of apoptosis 1-B OS=Xenopus laevis OX=8355 GN=triap1-b ... [more]
Q6INR61.8e-0738.18TP53-regulated inhibitor of apoptosis 1-A OS=Xenopus laevis OX=8355 GN=triap1-a ... [more]
Match NameE-valueIdentityDescription
A0A6J1GGR43.4e-41100.00uncharacterized protein At4g33100 isoform X2 OS=Cucurbita moschata OX=3662 GN=LO... [more]
A0A6J1GHR89.8e-41100.00uncharacterized protein At4g33100 isoform X1 OS=Cucurbita moschata OX=3662 GN=LO... [more]
A0A6J1KJX41.7e-4098.82uncharacterized protein At4g33100 isoform X4 OS=Cucurbita maxima OX=3661 GN=LOC1... [more]
A0A6J1KME94.8e-4098.81uncharacterized protein At4g33100 isoform X3 OS=Cucurbita maxima OX=3661 GN=LOC1... [more]
A0A6J1KNW54.8e-4098.81uncharacterized protein At4g33100 isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC1... [more]
Match NameE-valueIdentityDescription
AT4G33100.14.1e-2358.54CONTAINS InterPro DOMAIN/s: Mitochondrial distribution/morphology family 35/apop... [more]
InterPro
Analysis Name: InterPro Annotations of Cucurbita moschata (Rifu) v1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007918Mitochondrial distribution/morphology family 35/apoptosisPFAMPF05254UPF0203coord: 142..203
e-value: 7.2E-23
score: 80.6
IPR007918Mitochondrial distribution/morphology family 35/apoptosisPANTHERPTHR46403TP53-REGULATED INHIBITOR OF APOPTOSIS 1coord: 134..212
NoneNo IPR availablePROSITEPS51808CHCHcoord: 144..194
score: 12.963425

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
CmoCh12G005920.1CmoCh12G005920.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006470 protein dephosphorylation
molecular_function GO:0046872 metal ion binding
molecular_function GO:0004722 protein serine/threonine phosphatase activity