CmoCh11G012640 (gene) Cucurbita moschata (Rifu) v1

Overview


Name	CmoCh11G012640
Type	gene
Organism	Cucurbita moschata (Cucurbita moschata (Rifu) v1)
Description	methyl-CpG-binding domain protein 4-like protein
Location	Cmo_Chr11: 8062073 .. 8063360 (+)
RNA-Seq Expression	CmoCh11G012640
Synteny	CmoCh11G012640

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGTTGGGGAAATAAACTCCATGATACTATATATTATCGCAACCAAAACCTTCTATCATTTTGTATTTCTGTGTCAACTTTTTACTCATAATTGACCCTCTGTTTTCTGATTATGCACCCTTAGTCCTGTAGGTTTCATTTTTGCTGAAAATTTTCAGTTTGACTCAGTCTGCGAGTTCATTTTGAAAATTGCAGGCAAAAGAAGTGATACCTAAACTCTTCACTTTGTGTCCCGATCCAAAGTCTGCTTTGGAGGTATCGCAAGAGCAGATAGAAGATATTATTCGACCTCTTGGTTTACAAAGAAAAAGATCACTTACAATTCAGCGTTTATCTGAGATGTATTTAAAAGAAAGTTGGAGTCATGTCACTCAGCTTCCTGGTGTTGGGAAGTAATTTAGATCATCCTTTTAAACTCATTGATTTATAAGTTCTATCTCTTCCATGCTTATTGAGCTTGGGACGTGTATTAAAATGAATTTGATTTGAGACAGGTATGGAGCTGATGCACATGCAATATTTTGCACTGGATATTGGACCGAAGTATTGCCTAAAGATCACATGCTTAATTATTACTGGGAGTTTCTCCACAGCATAAAGCACCTGCTCTGATCTTATCTGAGGCAACTGTAGATGGTTCGACACGAGAGAAGCTGTAAATTTCCCGGTCTACTTAACATATATTTTTTGGTACGTTACTCTTTTGACATAATTTTGTTTTGTTAATGTTTATGTTGTTGTTGGGAGTCTGTGAGACCCTTATATCAACACATACTAGAAAGGGGAGAAATGGAAGCTCTCCTCCAAAAGCTAATTAGGCTGTAAGCTTGTATTGAGTGAAGTAGCGTGAGGGTCATGTTATGTTTTGAAAGGTCTGGTAGCTTTATTATGGGCTGTGCCTTCGCTTTTGACTTTTGAATATCAGTTTAGAAAGGAAGGATGATTAGCTTACCTATGATCTCTTTCTTTCTTGCTTTGGTAGGTTCAAAGTTCCTTTCACTTTAACCCGTATGGTCTTATCTTGATGAATTGTGGTTAGAAGTTGGCAAATGATGTAAGTGAAAACACCGGTAAGCTAATTACTATTTCTGGGTATTCAAATAGTTAATCACTGGCATAGCTAAAATTCGGTTGACATGGGCAATAATTTGTTCCACTTAAATCTATTATATAGACGCAGAGATGGATGCTTTGTGAACTCAGCCTCAAAATTTGTTGTTAAATTTAATTTGATTTATTGCATTCATTGTAAGCATTCTTGCTTTATTTTTCATAGTTCAGCCGTAA

mRNA sequence

ATGGTTGGGGAAATAAACTCCATGATACTATATATTATCGCAACCAAAACCTTCTATCATTTTGCAAAAGAAGTGATACCTAAACTCTTCACTTTGTGTCCCGATCCAAAGTCTGCTTTGGAGGTATCGCAAGAGCAGATAGAAGATATTATTCGACCTCTTGGTTTACAAAGAAAAAGATCACTTACAATTCAGCGTTTATCTGAGATGTATTTAAAAGAAAGTTGGAGTCATGTCACTCAGCTTCCTGGTGTTGGGAAGTATGGAGCTGATGCACATGCAATATTTTGCACTGGATATTGGACCGAACATAAAGCACCTGCTCTGATCTTATCTGAGGCAACTGTAGATGGTTCGACACGAGAGAAGCTGTTCAAAGTTCCTTTCACTTTAACCCGTATGCCGTAA

Coding sequence (CDS)

ATGGTTGGGGAAATAAACTCCATGATACTATATATTATCGCAACCAAAACCTTCTATCATTTTGCAAAAGAAGTGATACCTAAACTCTTCACTTTGTGTCCCGATCCAAAGTCTGCTTTGGAGGTATCGCAAGAGCAGATAGAAGATATTATTCGACCTCTTGGTTTACAAAGAAAAAGATCACTTACAATTCAGCGTTTATCTGAGATGTATTTAAAAGAAAGTTGGAGTCATGTCACTCAGCTTCCTGGTGTTGGGAAGTATGGAGCTGATGCACATGCAATATTTTGCACTGGATATTGGACCGAACATAAAGCACCTGCTCTGATCTTATCTGAGGCAACTGTAGATGGTTCGACACGAGAGAAGCTGTTCAAAGTTCCTTTCACTTTAACCCGTATGCCGTAA

Protein sequence

MVGEINSMILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRLSEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTEHKAPALILSEATVDGSTREKLFKVPFTLTRMP

Homology

[Close]

BLAST of CmoCh11G012640 vs. ExPASy Swiss-Prot
Match: Q0IGK1 (Methyl-CpG-binding domain protein 4-like protein OS=Arabidopsis thaliana OX=3702 GN=MBD4L PE=1 SV=1)

HSP 1 Score: 110.5 bits (275), Expect = 1.5e-23
Identity = 54/98 (55.10%), Postives = 71/98 (72.45%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  KT     + VI  LF LC D K+A EV +E+IE++I+PLGLQ+KR+  IQRL
Sbjct: 329 LVICMLLNKTSGAQTRGVISDLFGLCTDAKTATEVKEEEIENLIKPLGLQKKRTKMIQRL 388

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTEHK 106
           S  YL+ESW+HVTQL GVGKY ADA+AIFC G W   K
Sbjct: 389 SLEYLQESWTHVTQLHGVGKYAADAYAIFCNGNWDRVK 426

[Close]

BLAST of CmoCh11G012640 vs. ExPASy Swiss-Prot
Match: O95243 (Methyl-CpG-binding domain protein 4 OS=Homo sapiens OX=9606 GN=MBD4 PE=1 SV=1)

HSP 1 Score: 62.0 bits (149), Expect = 6.0e-09
Identity = 30/96 (31.25%), Postives = 49/96 (51.04%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +I  I   +T    A  V+ K     P  + A       + ++++PLGL   R+ TI + 
Sbjct: 460 LIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKF 519

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           S+ YL + W +  +L G+GKYG D++ IFC   W +
Sbjct: 520 SDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQ 555

[Close]

BLAST of CmoCh11G012640 vs. ExPASy Swiss-Prot
Match: Q9Z2D7 (Methyl-CpG-binding domain protein 4 OS=Mus musculus OX=10090 GN=Mbd4 PE=1 SV=1)

HSP 1 Score: 59.7 bits (143), Expect = 3.0e-08
Identity = 29/96 (30.21%), Postives = 49/96 (51.04%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +I  I   +T    A  V+ +     P  + A       + ++++PLGL   R+ TI + 
Sbjct: 434 LIATIFLNRTSGKMAIPVLWEFLEKYPSAEVARAADWRDVSELLKPLGLYDLRAKTIIKF 493

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           S+ YL + W +  +L G+GKYG D++ IFC   W +
Sbjct: 494 SDEYLTKQWRYPIELHGIGKYGNDSYRIFCVNEWKQ 529

[Close]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL
Match: A0A6J1HWM5 (methyl-CpG-binding domain protein 4-like protein isoform X1 OS=Cucurbita maxima OX=3661 GN=LOC111468538 PE=4 SV=1)

HSP 1 Score: 172.9 bits (437), Expect = 8.8e-40
Identity = 83/96 (86.46%), Postives = 89/96 (92.71%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  +T    AKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL
Sbjct: 358 LVICMLLNRTTGQQAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 417

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE
Sbjct: 418 SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 453

[Close]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL
Match: A0A6J1EZJ4 (methyl-CpG-binding domain protein 4-like protein OS=Cucurbita moschata OX=3662 GN=LOC111437878 PE=4 SV=1)

HSP 1 Score: 172.9 bits (437), Expect = 8.8e-40
Identity = 83/96 (86.46%), Postives = 89/96 (92.71%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  +T    AKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL
Sbjct: 425 LVICMLLNRTTGQQAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 484

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE
Sbjct: 485 SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 520

[Close]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL
Match: A0A6J1DRX8 (methyl-CpG-binding domain protein 4-like protein OS=Momordica charantia OX=3673 GN=LOC111023823 PE=4 SV=1)

HSP 1 Score: 161.0 bits (406), Expect = 3.5e-36
Identity = 76/96 (79.17%), Postives = 86/96 (89.58%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  +T    AK+VIPKLFTLCP+PK+ALEVS EQIEDIIRPLGLQRKRS TIQRL
Sbjct: 334 LLICLLLNRTSGRQAKDVIPKLFTLCPNPKAALEVSHEQIEDIIRPLGLQRKRSRTIQRL 393

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYW +
Sbjct: 394 SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWDQ 429

[Close]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL
Match: A0A1S3CCU6 (methyl-CpG-binding domain protein 4-like protein OS=Cucumis melo OX=3656 GN=LOC103499353 PE=4 SV=1)

HSP 1 Score: 156.0 bits (393), Expect = 1.1e-34
Identity = 73/96 (76.04%), Postives = 85/96 (88.54%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  +T    AKEVIPKLF+LCP+PK+ LEVS+EQIEDIIRPLGL RKRS T+ RL
Sbjct: 371 LVICMLLNRTSGRQAKEVIPKLFSLCPNPKATLEVSREQIEDIIRPLGLYRKRSRTMHRL 430

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTE 104
           SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYW+E
Sbjct: 431 SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWSE 466

[Close]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL
Match: A0A5D3CU57 (Methyl-CpG-binding domain protein 4-like protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold45G00130 PE=4 SV=1)

HSP 1 Score: 153.3 bits (386), Expect = 7.3e-34
Identity = 72/94 (76.60%), Postives = 83/94 (88.30%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  +T    AKEVIPKLF+LCP+PK+ LEVS+EQIEDIIRPLGL RKRS T+ RL
Sbjct: 371 LVICMLLNRTSGRQAKEVIPKLFSLCPNPKATLEVSREQIEDIIRPLGLYRKRSRTMHRL 430

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYW 102
           SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYW
Sbjct: 431 SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYW 464

[Close]

BLAST of CmoCh11G012640 vs. TAIR 10
Match: AT3G07930.3 (DNA glycosylase superfamily protein )

HSP 1 Score: 110.5 bits (275), Expect = 1.0e-24
Identity = 54/98 (55.10%), Postives = 71/98 (72.45%), Query Frame = 0


Query: 8   MILYIIATKTFYHFAKEVIPKLFTLCPDPKSALEVSQEQIEDIIRPLGLQRKRSLTIQRL 67
           +++ ++  KT     + VI  LF LC D K+A EV +E+IE++I+PLGLQ+KR+  IQRL
Sbjct: 329 LVICMLLNKTSGAQTRGVISDLFGLCTDAKTATEVKEEEIENLIKPLGLQKKRTKMIQRL 388

Query: 68  SEMYLKESWSHVTQLPGVGKYGADAHAIFCTGYWTEHK 106
           S  YL+ESW+HVTQL GVGKY ADA+AIFC G W   K
Sbjct: 389 SLEYLQESWTHVTQLHGVGKYAADAYAIFCNGNWDRVK 426

The following BLAST results are available for this feature:

BLAST of CmoCh11G012640 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q0IGK1	1.5e-23	55.10	Methyl-CpG-binding domain protein 4-like protein OS=Arabidopsis thaliana OX=3702...	[more]
O95243	6.0e-09	31.25	Methyl-CpG-binding domain protein 4 OS=Homo sapiens OX=9606 GN=MBD4 PE=1 SV=1	[more]
Q9Z2D7	3.0e-08	30.21	Methyl-CpG-binding domain protein 4 OS=Mus musculus OX=10090 GN=Mbd4 PE=1 SV=1	[more]

BLAST of CmoCh11G012640 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1HWM5	8.8e-40	86.46	methyl-CpG-binding domain protein 4-like protein isoform X1 OS=Cucurbita maxima ...	[more]
A0A6J1EZJ4	8.8e-40	86.46	methyl-CpG-binding domain protein 4-like protein OS=Cucurbita moschata OX=3662 G...	[more]
A0A6J1DRX8	3.5e-36	79.17	methyl-CpG-binding domain protein 4-like protein OS=Momordica charantia OX=3673 ...	[more]
A0A1S3CCU6	1.1e-34	76.04	methyl-CpG-binding domain protein 4-like protein OS=Cucumis melo OX=3656 GN=LOC1...	[more]
A0A5D3CU57	7.3e-34	76.60	Methyl-CpG-binding domain protein 4-like protein OS=Cucumis melo var. makuwa OX=...	[more]

BLAST of CmoCh11G012640 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G07930.3	1.0e-24	55.10	DNA glycosylase superfamily protein	[more]

InterPro

Analysis Name: InterPro Annotations of Cucurbita moschata (Rifu) v1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	1.10.340.30	Hypothetical protein; domain 2	coord: 6..111 e-value: 2.5E-24 score: 87.5
None	No IPR available	PANTHER	PTHR15074:SF0	METHYL-CPG-BINDING DOMAIN PROTEIN 4-RELATED	coord: 22..103
IPR003265	HhH-GPD domain	PFAM	PF00730	HhH-GPD	coord: 15..92 e-value: 3.1E-6 score: 27.6
IPR045138	Methyl-CpG binding protein MeCP2/MBD4	PANTHER	PTHR15074	METHYL-CPG-BINDING PROTEIN	coord: 22..103
IPR011257	DNA glycosylase	SUPERFAMILY	48150	DNA-glycosylase	coord: 8..103

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CmoCh11G012640.1	CmoCh11G012640.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006284	base-excision repair
biological_process	GO:0006281	DNA repair
molecular_function	GO:0003824	catalytic activity
molecular_function	GO:0003677	DNA binding