CmaCh16G004540 (gene) Cucurbita maxima (Rimu) v1.1

Overview
NameCmaCh16G004540
Typegene
OrganismCucurbita maxima (Cucurbita maxima (Rimu) v1.1)
Descriptionheme-binding protein 2-like
LocationCma_Chr16: 2274841 .. 2276821 (-)
RNA-Seq ExpressionCmaCh16G004540
SyntenyCmaCh16G004540
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDSthree_prime_UTR
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGCGATGGCCGCCATTGAAATGCTCAAGCTCTCGCTTCTCACAACCCTAATCCTTTTGATCCTCAGGCCCGCCTACTCGGAGCTTCCTCCGTCGTGCAAGCGCATCGAGTGCCCTAGCTACGACGTCATCGACTCCGGCAAAGGGTTCGAGATTCGGCGCTATGATTCCTCTGTTTGGGCCTCCACCGCTCCAATTCCTGATATTTCTCTCCATGAAGCCACCAGAACAGGATTTCTCAAGTAAATTACACTTTCTTTTCTCATCTGATTTCATTCATTTTACTTCCATATATGATATCTGTTACAGATTAGGTTTCTCCGATTTTGCTAACCTAACTTATGAACAAATTCATCTTCCACTTCACATATTCAAATTCCTATCAGCTCCATAGATACTTCAAGATTACTAAGAAATTTCTGCAATATCTCTCTTGGTTGAAATTCATTAGCCATCTTGAGCAGTTCATCTAGTTTGTCTAAGGCATTCTATCAATTATATGGAGAAAATTGAACAATCTCTTGCAGGTGCTATAGTAATTCCTTTTGAATTAAACTAATACAAATCTAGGAGTTCATGAGACTGAAACAGGGGTAGGTCTTTAGCTTGGCTATCGGCCTGTCTTTTTTTCTTTTTCGCAAAGTTTTGGTAACCGGTAGACAATAGAGTCAGTTCGTTGATAGCCGCAAGCAAGCGTAGTAGGCCCTGAACCCAATCGAACTATGTCTATCCCCAACTTCATTGTCTTGACTTGTTTATGGTGAAATTAGTCTAAAAGAAGGAAAGAACACGGGATCACTATTTAGTCGAATGAGTCTATCCTAGGTCAAAGGTTAAGGTATCAACATCTAAAAATGAGGTGTTGATTGACCATTGATTGAAAAGCCCACTTCTCTCTGACAAAGCAACTTTCCGAAATAGAGTAGAGCGTGAGGGCAGAAAGACGACTACAACAATTGGAACTATCTCGCTGGAACACCTAGAATTGCCAAATCTCTCTCTTTTACGCTCGAGAGTGAAATTCTCACGAGAAGAAGAAGCTCTTCTCTTAGCTATGACGAGAGCTCAAAATTCTCCACAAAAAGTCCTTGAATTAAATGAATATAAGTTTTGTTATTTTCACGTTCAAGTTTCTAAACTTTCAATTCATTAGATCACATTGTTTATTTCATTAGATTGTTCGATTACATTCAAGGAAAGAACAAGTACAACGAAAAGATAGAGATGACTGCACCGGTGCTCACAGAGGTTTCTCCGAGCGACGGACCCTTTTGTGAATCATCATTCGTGGTTAGCTTCTACGTGCCGAAAGTGAACCAAGCAGACCCTCCACCAGCCAAGGGGCTTCACATTCAGAGATGGAAAGAAACACACGTCGCAGTAAGACAATTTGGAGGGTTTGTGTCTGATGCGACAATTGGAGCTGAGGCTGCTGCGTTGGATGAGAGTGTTTTCGACACAAAGTGGGCAGCAGCCATCAGCAAGAGCCGTGGCGCTGGCGGTGCTGCCATTTACACAGTGGCTCAGTACAACTCCCCTTTTGAGTTTGAAGGTCGTGTCAATGAGATTTGGTTCTTGTTTGATATTGAAGATGCTGCTGCTGATGCTGCTGCTCAGGCTTAGAAACTGATGTCTGGAATCTTCATATAGTAAGTAAAATGTATGAAGACTTCAAACTTTTTCTGTTCTTGTTCATGAATCCTTCAATAAAATGTTCGAGTTCTACACATTGATCTTTGTAACTTGGATTCAAATGTTCGGGTCTTTCTAAAGGTTTTCCACACCCTTATATGTGTGGTACAACTCTCCACAATGGTATGATATTGAGACCTTCGAGGAGTCACTCCCTTTTTCTTTTGGAGTGCTTTGTACGACATTTGGGGATTCTATTAACATGGTTAAGACTCTAGTACCATGTTAGATGAACACGATTCTCCATAATGGTATGATATTGTCCACTTTAAACATAAACCCTCGTGGC

mRNA sequence

ATGGCGATGGCCGCCATTGAAATGCTCAAGCTCTCGCTTCTCACAACCCTAATCCTTTTGATCCTCAGGCCCGCCTACTCGGAGCTTCCTCCGTCGTGCAAGCGCATCGAGTGCCCTAGCTACGACGTCATCGACTCCGGCAAAGGGTTCGAGATTCGGCGCTATGATTCCTCTGTTTGGGCCTCCACCGCTCCAATTCCTGATATTTCTCTCCATGAAGCCACCAGAACAGGATTTCTCAAATTGTTCGATTACATTCAAGGAAAGAACAAGTACAACGAAAAGATAGAGATGACTGCACCGGTGCTCACAGAGGTTTCTCCGAGCGACGGACCCTTTTGTGAATCATCATTCGTGGTTAGCTTCTACGTGCCGAAAGTGAACCAAGCAGACCCTCCACCAGCCAAGGGGCTTCACATTCAGAGATGGAAAGAAACACACGTCGCAGTAAGACAATTTGGAGGGTTTGTGTCTGATGCGACAATTGGAGCTGAGGCTGCTGCGTTGGATGAGAGTGTTTTCGACACAAAGTGGGCAGCAGCCATCAGCAAGAGCCGTGGCGCTGGCGGTGCTGCCATTTACACAGTGGCTCAGTACAACTCCCCTTTTGAGTTTGAAGGTCGTGTCAATGAGATTTGGTTCTTGTTTGATATTGAAGATGCTGCTGCTGATGCTGCTGCTCAGGCTTAGAAACTGATGTCTGGAATCTTCATATAGTAAGTAAAATGTATGAAGACTTCAAACTTTTTCTGTTCTTGTTCATGAATCCTTCAATAAAATGTTCGAGTTCTACACATTGATCTTTGTAACTTGGATTCAAATGTTCGGGTCTTTCTAAAGGTTTTCCACACCCTTATATGTGTGGTACAACTCTCCACAATGGTATGATATTGAGACCTTCGAGGAGTCACTCCCTTTTTCTTTTGGAGTGCTTTGTACGACATTTGGGGATTCTATTAACATGGTTAAGACTCTAGTACCATGTTAGATGAACACGATTCTCCATAATGGTATGATATTGTCCACTTTAAACATAAACCCTCGTGGC

Coding sequence (CDS)

ATGGCGATGGCCGCCATTGAAATGCTCAAGCTCTCGCTTCTCACAACCCTAATCCTTTTGATCCTCAGGCCCGCCTACTCGGAGCTTCCTCCGTCGTGCAAGCGCATCGAGTGCCCTAGCTACGACGTCATCGACTCCGGCAAAGGGTTCGAGATTCGGCGCTATGATTCCTCTGTTTGGGCCTCCACCGCTCCAATTCCTGATATTTCTCTCCATGAAGCCACCAGAACAGGATTTCTCAAATTGTTCGATTACATTCAAGGAAAGAACAAGTACAACGAAAAGATAGAGATGACTGCACCGGTGCTCACAGAGGTTTCTCCGAGCGACGGACCCTTTTGTGAATCATCATTCGTGGTTAGCTTCTACGTGCCGAAAGTGAACCAAGCAGACCCTCCACCAGCCAAGGGGCTTCACATTCAGAGATGGAAAGAAACACACGTCGCAGTAAGACAATTTGGAGGGTTTGTGTCTGATGCGACAATTGGAGCTGAGGCTGCTGCGTTGGATGAGAGTGTTTTCGACACAAAGTGGGCAGCAGCCATCAGCAAGAGCCGTGGCGCTGGCGGTGCTGCCATTTACACAGTGGCTCAGTACAACTCCCCTTTTGAGTTTGAAGGTCGTGTCAATGAGATTTGGTTCTTGTTTGATATTGAAGATGCTGCTGCTGATGCTGCTGCTCAGGCTTAG

Protein sequence

MAMAAIEMLKLSLLTTLILLILRPAYSELPPSCKRIECPSYDVIDSGKGFEIRRYDSSVWASTAPIPDISLHEATRTGFLKLFDYIQGKNKYNEKIEMTAPVLTEVSPSDGPFCESSFVVSFYVPKVNQADPPPAKGLHIQRWKETHVAVRQFGGFVSDATIGAEAAALDESVFDTKWAAAISKSRGAGGAAIYTVAQYNSPFEFEGRVNEIWFLFDIEDAAADAAAQA
Homology
BLAST of CmaCh16G004540 vs. ExPASy Swiss-Prot
Match: Q9Y5Z4 (Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2 PE=1 SV=1)

HSP 1 Score: 105.9 bits (263), Expect = 6.1e-22
Identity = 65/174 (37.36%), Postives = 84/174 (48.28%), Query Frame = 0

Query: 50  FEIRRYDSSVWASTAPIPDISLHEATRTGFLKLFDYIQGKNKYNEKIEMTAPVLTEVSPS 109
           +EIR Y  + W ST+ +  +    A +TGF KL  YIQGKN+   KI+MTAPV + V P 
Sbjct: 38  YEIRHYGPAKWVSTS-VESMDWDSAIQTGFTKLNSYIQGKNEKEMKIKMTAPVTSYVEPG 97

Query: 110 DGPFCESSFVVSFYVPKVNQADPPP--AKGLHIQRWKETHVAVRQFGGFVSDATIGAEAA 169
            GPF ES+  +S Y+P   Q DPP      + I+   E  V VR F GF S      +  
Sbjct: 98  SGPFSESTITISLYIPSEQQFDPPRPLESDVFIEDRAEMTVFVRSFDGFSSAQKNQEQLL 157

Query: 170 AL------DESVFDTKWAAAISKSRGAGGAAIYTVAQYNSPFEFEGRVNEIWFL 216
            L      D  VFD K               +Y  A YNSP +   R NE+W +
Sbjct: 158 TLASILREDGKVFDEK---------------VYYTAGYNSPVKLLNRNNEVWLI 195

BLAST of CmaCh16G004540 vs. ExPASy Swiss-Prot
Match: Q9WU63 (Heme-binding protein 2 OS=Mus musculus OX=10090 GN=Hebp2 PE=1 SV=1)

HSP 1 Score: 100.5 bits (249), Expect = 2.6e-20
Identity = 63/186 (33.87%), Postives = 91/186 (48.92%), Query Frame = 0

Query: 36  IECPSY----DVIDSGKGFEIRRYDSSVWASTAPIPDISLHEATRTGFLKLFDYIQGKNK 95
           +E PS+    D+      +EIR Y  + W ST  +  +    A +TGF KL  YIQGKN+
Sbjct: 20  LEMPSWKAPEDIDPQPGSYEIRHYGPAKWVSTC-VESLDWDSAIQTGFTKLNGYIQGKNE 79

Query: 96  YNEKIEMTAPVLTEVSPSDGPFCESSFVVSFYVPKVNQADPP-PAKG-LHIQRWKETHVA 155
              KI++TAPV + V P   PF ES+  +S Y+P   Q DPP P++  + I+   E  V 
Sbjct: 80  KEMKIKLTAPVTSYVEPGSSPFSESTITISLYIPSEQQPDPPRPSESDVFIEDRAEMTVF 139

Query: 156 VRQFGGFVSDATIGAEAAALDESVFDTKWAAAISKSRGAGGAAIYTVAQYNSPFEFEGRV 215
           VR F GF S      +   L         A  + +        ++  A Y+SPF+   R 
Sbjct: 140 VRSFDGFSSGQKNQEQLLTL---------ANILREEGKVFNEKVFYTAGYSSPFQLLDRN 195

BLAST of CmaCh16G004540 vs. ExPASy Swiss-Prot
Match: Q9SR77 (Heme-binding-like protein At3g10130, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=At3g10130 PE=1 SV=1)

HSP 1 Score: 52.0 bits (123), Expect = 1.0e-05
Identity = 54/198 (27.27%), Postives = 83/198 (41.92%), Query Frame = 0

Query: 22  LRPAYSELPPSCKRIECPSYDVIDSGKGFEIRRYDSSVWASTAPIPDISLHE-ATRTGFL 81
           L  A+  +P     +E  ++ V+     +EIR+ +    A T    +           F 
Sbjct: 104 LEEAFMSVPD----LETMNFRVLFRTDKYEIRQVEPYFVAETIMPGETGFDSYGASKSFN 163

Query: 82  KLFDYIQGKNKYNEKIEMTAPVLTEVSPSDGPFCE-------------SSFVVSFYVPKV 141
            L +Y+ GKN   EK+EMT PV+T    S G   E             + + +SF +P  
Sbjct: 164 VLAEYLFGKNTIKEKMEMTTPVVTRKVQSVGEKMEMTTPVITSKAKDQNQWRMSFVMPSK 223

Query: 142 NQADPPPAK--GLHIQRWKETHVAVRQFGGFVSDATIGAEAAALDESVFDTKWAAAISKS 201
             ++ P  K   + IQ+     VAV  F G+V+D  I      L  ++ + K      K 
Sbjct: 224 YGSNLPLPKDPSVKIQQVPRKIVAVVAFSGYVTDEEIERRERELRRALQNDK------KF 283

Query: 202 RGAGGAAIYTVAQYNSPF 204
           R   G + + VAQYN PF
Sbjct: 284 RVRDGVS-FEVAQYNPPF 290

BLAST of CmaCh16G004540 vs. TAIR 10
Match: AT1G17100.1 (SOUL heme-binding family protein )

HSP 1 Score: 281.6 bits (719), Expect = 5.8e-76
Identity = 130/195 (66.67%), Postives = 159/195 (81.54%), Query Frame = 0

Query: 28  ELPPSCKRIECPSYDVIDSGKGFEIRRYDSSVWASTAPIPDISLHEATRTGFLKLFDYIQ 87
           + PPSC RIECPSY+++ SG G+EIRRY+++VW ST PIPDISL +ATRT F +LF YIQ
Sbjct: 37  KFPPSCNRIECPSYELVHSGNGYEIRRYNNTVWVSTEPIPDISLVDATRTAFFQLFAYIQ 96

Query: 88  GKNKYNEKIEMTAPVLTEVSPSDGPFCESSFVVSFYVPKVNQADPPPAKGLHIQRWKETH 147
           GKN+Y++KIEMTAPV+++VSPSDGPFCESSF VSFYVPK NQ DP P++ LHIQ+W   +
Sbjct: 97  GKNEYHQKIEMTAPVISQVSPSDGPFCESSFTVSFYVPKKNQPDPAPSENLHIQKWNSRY 156

Query: 148 VAVRQFGGFVSDATIGAEAAALDESVFDTKWAAAISKSR---GAGGAAIYTVAQYNSPFE 207
           VAVRQF GFVSD +IG +AAALD S+  T WA AI+KS+   G G  + YTVAQYNSPFE
Sbjct: 157 VAVRQFSGFVSDDSIGEQAAALDSSLKGTAWANAIAKSKEDGGVGSDSAYTVAQYNSPFE 216

Query: 208 FEGRVNEIWFLFDIE 220
           F GRVNEIW  F+++
Sbjct: 217 FSGRVNEIWLPFELD 231

BLAST of CmaCh16G004540 vs. TAIR 10
Match: AT1G78450.1 (SOUL heme-binding family protein )

HSP 1 Score: 211.8 bits (538), Expect = 5.6e-55
Identity = 109/220 (49.55%), Postives = 147/220 (66.82%), Query Frame = 0

Query: 4   AAIEMLKLSLLTTLILLILRPAYSELPPSCKRIECPSYDVIDSGKGFEIRRYDSSVWAST 63
           AA+ + KLS L TL L         LPP+C R ECPSY+V+ +G G+EI RY+++VW ST
Sbjct: 3   AALSIFKLSFLLTL-LSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWIST 62

Query: 64  APIPDISLHEATRTGFLKLFDYIQGKNKYNEKIEMTAPVLTEVSPSDGPFCESSFVVSFY 123
            PI DISL+EA+  G+ +L DY+ G N Y+++IE+  P +T+VS +      S+F+VSF+
Sbjct: 63  EPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQN-----LSTFIVSFF 122

Query: 124 VPKVNQADPPPAKGLHIQRWKETHVAVRQFGGFVSDATIGAEAAALDESVFDTKWAAAIS 183
           VPK  Q DPPP   LH+QRW   +VAV+Q  G+V+D  IG + A L  S+  T WA AI 
Sbjct: 123 VPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIE 182

Query: 184 KSR---GAGGAAIYTVAQYNSPFEFEGRVNEIWFLFDIED 221
           KSR   G G A  YTVAQ++ PF++  RVNEIWF F++ED
Sbjct: 183 KSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMED 216

BLAST of CmaCh16G004540 vs. TAIR 10
Match: AT1G78460.1 (SOUL heme-binding family protein )

HSP 1 Score: 171.4 bits (433), Expect = 8.4e-43
Identity = 96/222 (43.24%), Postives = 137/222 (61.71%), Query Frame = 0

Query: 6   IEMLKLSLLTTLILL--------ILRPAYSELPPSCKRIECPSYDVIDSGKGFEIRRYDS 65
           + +LKLSL  +L+++           P+    P +C   ECP+Y ++++G GFEIR YD+
Sbjct: 5   LNILKLSLCVSLVVVGSYAQAPAPWNPSNGFRPGTCDHYECPTYKLVEAGYGFEIRMYDA 64

Query: 66  SVWASTAPIPDISLHEATRTGFLKLFDYIQGKNKYNEKIEMTAPVLTEVSPSDGPFCESS 125
           ++W ST+PIP +S+ +AT+TGF +L  YI+G NK N K+ MTAPV+ + +P       S 
Sbjct: 65  ALWISTSPIPSLSMTQATKTGFRRLNRYIEGDNKSNVKMNMTAPVIAQATPG-----RSV 124

Query: 126 FVVSFYVPKVNQADPPPAKGLHIQRWKETHVAVRQFGGFVSDATIGAEAAALDESVFDTK 185
           + VS Y+PK NQ +PP A  LH++  K T+VAVRQ GG+VS+     EAAAL ES+ D+ 
Sbjct: 125 YTVSLYLPKKNQQNPPQADDLHVRSTKPTYVAVRQIGGYVSNNVAKDEAAALMESLRDSN 184

Query: 186 WAAAISKSRGAGGAAIYTVAQYNSPFEFEGRV-NEIWFLFDI 219
           W   I KS+G   A  Y +A YN P     RV NEI   F++
Sbjct: 185 WILPIEKSKGKLPA--YFLAVYNPPSHTTARVINEIMVPFNM 219

BLAST of CmaCh16G004540 vs. TAIR 10
Match: AT3G10130.1 (SOUL heme-binding family protein )

HSP 1 Score: 52.0 bits (123), Expect = 7.4e-07
Identity = 54/198 (27.27%), Postives = 83/198 (41.92%), Query Frame = 0

Query: 22  LRPAYSELPPSCKRIECPSYDVIDSGKGFEIRRYDSSVWASTAPIPDISLHE-ATRTGFL 81
           L  A+  +P     +E  ++ V+     +EIR+ +    A T    +           F 
Sbjct: 104 LEEAFMSVPD----LETMNFRVLFRTDKYEIRQVEPYFVAETIMPGETGFDSYGASKSFN 163

Query: 82  KLFDYIQGKNKYNEKIEMTAPVLTEVSPSDGPFCE-------------SSFVVSFYVPKV 141
            L +Y+ GKN   EK+EMT PV+T    S G   E             + + +SF +P  
Sbjct: 164 VLAEYLFGKNTIKEKMEMTTPVVTRKVQSVGEKMEMTTPVITSKAKDQNQWRMSFVMPSK 223

Query: 142 NQADPPPAK--GLHIQRWKETHVAVRQFGGFVSDATIGAEAAALDESVFDTKWAAAISKS 201
             ++ P  K   + IQ+     VAV  F G+V+D  I      L  ++ + K      K 
Sbjct: 224 YGSNLPLPKDPSVKIQQVPRKIVAVVAFSGYVTDEEIERRERELRRALQNDK------KF 283

Query: 202 RGAGGAAIYTVAQYNSPF 204
           R   G + + VAQYN PF
Sbjct: 284 RVRDGVS-FEVAQYNPPF 290

BLAST of CmaCh16G004540 vs. TAIR 10
Match: AT5G20140.1 (SOUL heme-binding family protein )

HSP 1 Score: 47.4 bits (111), Expect = 1.8e-05
Identity = 33/141 (23.40%), Postives = 62/141 (43.97%), Query Frame = 0

Query: 36  IECPSYDVIDSGKGFEIRRYDSSVWASTAPIPDISLHEATRTGFLKLFDYIQGKNKYNEK 95
           +E P Y ++     +E+R Y+  +   T     I    +  +GF  +  YI GKN   EK
Sbjct: 205 LETPKYQILKRTANYEVRNYEPFIVVET-----IGDKLSGSSGFNNVAGYIFGKNSTMEK 264

Query: 96  IEMTAPVLTEVSPSDGPFCESSFVVSFYVPK---VNQADPPPAKGLHIQRWKETHVAVRQ 155
           I MT PV T+ + +      S   V   +P    ++    P  + +++++ +    A  +
Sbjct: 265 IPMTTPVFTQTTDTQ---LSSDVSVQIVIPSGKDLSSLPMPNEEKVNLKKLEGGFAAAVK 324

Query: 156 FGGFVSDATIGAEAAALDESV 174
           F G  ++  + A+   L  S+
Sbjct: 325 FSGKPTEDVVQAKENELRSSL 337

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q9Y5Z46.1e-2237.36Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2 PE=1 SV=1[more]
Q9WU632.6e-2033.87Heme-binding protein 2 OS=Mus musculus OX=10090 GN=Hebp2 PE=1 SV=1[more]
Q9SR771.0e-0527.27Heme-binding-like protein At3g10130, chloroplastic OS=Arabidopsis thaliana OX=37... [more]
Match NameE-valueIdentityDescription
AT1G17100.15.8e-7666.67SOUL heme-binding family protein [more]
AT1G78450.15.6e-5549.55SOUL heme-binding family protein [more]
AT1G78460.18.4e-4343.24SOUL heme-binding family protein [more]
AT3G10130.17.4e-0727.27SOUL heme-binding family protein [more]
AT5G20140.11.8e-0523.40SOUL heme-binding family protein [more]
InterPro
Analysis Name: InterPro Annotations of Cucurbita maxima (Rimu) v1.1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006917SOUL haem-binding proteinPFAMPF04832SOULcoord: 36..214
e-value: 1.6E-46
score: 158.6
IPR006917SOUL haem-binding proteinPANTHERPTHR11220HEME-BINDING PROTEIN-RELATEDcoord: 3..222
IPR011256Regulatory factor, effector binding domain superfamilyGENE3D3.20.80.10Regulatory factor, effector binding domaincoord: 35..225
e-value: 2.0E-53
score: 182.8
IPR011256Regulatory factor, effector binding domain superfamilySUPERFAMILY55136Probable bacterial effector-binding domaincoord: 29..216
NoneNo IPR availablePANTHERPTHR11220:SF25F3F9.4coord: 3..222

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
CmaCh16G004540.1CmaCh16G004540.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0110165 cellular anatomical entity