CmaCh16G000740 (gene) Cucurbita maxima (Rimu) v1.1

Overview


Name	CmaCh16G000740
Type	gene
Organism	Cucurbita maxima (Cucurbita maxima (Rimu) v1.1)
Description	arabinogalactan peptide 22-like
Location	Cma_Chr16: 320475 .. 321267 (+)
RNA-Seq Expression	CmaCh16G000740
Synteny	CmaCh16G000740

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRCDSpolypeptidethree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

AGAGCATAAAAAAGAAGGAATCTGTGAATGAATGAAGAATCATCACATGGGTTTGCGTGGGATTCCCAAAACTTGCGCTCCAAACCCAAACACTATTAATAAACCCCAATCCCTTCATCTCCACACACCCTTGTTCTTGTTCTTGTTCTTGTTCTTGTGTATCTCAGCATTGGATTGAATAATCGCCAAAGACAGAGAGATGGGTGTTTTGAGGGCTTGTTTTGGGATCTATGCTGTGATTATTGCTGTGGTTTATGTTGTTATGTTGCCTGTATCTGCTGCAGCGGAACATTCATCTTTTCCAGCTCCAGCCCCAGCCCCCACTAGTGATGGTTACTTCTCTCTTCTTCCTGCTTTTCTGCTTATTGCTTCAATACAAAACAAAATCTACTCTTTCTTTTTCTGCTAATAAGACTTGCGATTTCATATGTTGCAGGCACCACAATAGACCAAGGCATAGCATATATTCTAATGCTGCTGGCTTTAGCGCTCACTTATATCATCCATTGATGCAACTTCCGAAAGCACCAAACGCAGAAGAACACTAACAGCATTCAATTCCGATTATGAATTACATTTTCAAGTGAGCGAGTTGAAAGGGAAGATGGTGTGGTTGTTTCATTCAAATGGGACTTTTTTTTTTCTCTTCTTTTCCTTCTTAAAAATTGGCAGAGATTTCATTTCCAGAAGCTCTGTTATACTTGTATTATATATTCATTATTATTATTATTTTCTTCATTCATCATTATTTTCCTTTGTGTATTCTAAATGGAAGACATATAAGATTTGACGG

mRNA sequence

AGAGCATAAAAAAGAAGGAATCTGTGAATGAATGAAGAATCATCACATGGGTTTGCGTGGGATTCCCAAAACTTGCGCTCCAAACCCAAACACTATTAATAAACCCCAATCCCTTCATCTCCACACACCCTTGTTCTTGTTCTTGTTCTTGTTCTTGTGTATCTCAGCATTGGATTGAATAATCGCCAAAGACAGAGAGATGGGTGTTTTGAGGGCTTGTTTTGGGATCTATGCTGTGATTATTGCTGTGGTTTATGTTGTTATGTTGCCTGTATCTGCTGCAGCGGAACATTCATCTTTTCCAGCTCCAGCCCCAGCCCCCACTAGTGATGGCACCACAATAGACCAAGGCATAGCATATATTCTAATGCTGCTGGCTTTAGCGCTCACTTATATCATCCATTGATGCAACTTCCGAAAGCACCAAACGCAGAAGAACACTAACAGCATTCAATTCCGATTATGAATTACATTTTCAAGTGAGCGAGTTGAAAGGGAAGATGGTGTGGTTGTTTCATTCAAATGGGACTTTTTTTTTTCTCTTCTTTTCCTTCTTAAAAATTGGCAGAGATTTCATTTCCAGAAGCTCTGTTATACTTGTATTATATATTCATTATTATTATTATTTTCTTCATTCATCATTATTTTCCTTTGTGTATTCTAAATGGAAGACATATAAGATTTGACGG

Coding sequence (CDS)

ATGGGTGTTTTGAGGGCTTGTTTTGGGATCTATGCTGTGATTATTGCTGTGGTTTATGTTGTTATGTTGCCTGTATCTGCTGCAGCGGAACATTCATCTTTTCCAGCTCCAGCCCCAGCCCCCACTAGTGATGGCACCACAATAGACCAAGGCATAGCATATATTCTAATGCTGCTGGCTTTAGCGCTCACTTATATCATCCATTGA

Protein sequence

MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALTYIIH

Homology

[Close]

BLAST of CmaCh16G000740 vs. ExPASy Swiss-Prot
Match: Q8L9T8 (Arabinogalactan protein 41 OS=Arabidopsis thaliana OX=3702 GN=AGP41 PE=1 SV=1)

HSP 1 Score: 68.9 bits (167), Expect = 2.5e-11
Identity = 36/64 (56.25%), Postives = 51/64 (79.69%), Query Frame = 0


Query: 5  RACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALT 64
          R  FG+ + I+++++ ++LP++    H+   APAPAPTSDGTTIDQGIAY+LML+AL LT
Sbjct: 5  RLFFGV-STIVSIIFAILLPMA----HAQSAAPAPAPTSDGTTIDQGIAYVLMLVALVLT 63

Query: 65 YIIH 69
          Y+IH
Sbjct: 65 YLIH 63

[Close]

BLAST of CmaCh16G000740 vs. ExPASy Swiss-Prot
Match: Q9FK16 (Arabinogalactan protein 22 OS=Arabidopsis thaliana OX=3702 GN=AGP22 PE=1 SV=1)

HSP 1 Score: 62.0 bits (149), Expect = 3.0e-09
Identity = 39/68 (57.35%), Postives = 51/68 (75.00%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  L+    I AV + ++ V++LP+  A  HSS  +PAPAPTSDGT+IDQGIAY+LM++A
Sbjct: 1  MASLKFPLEILAVFV-IISVILLPI--AQSHSS--SPAPAPTSDGTSIDQGIAYVLMMVA 60

Query: 61 LALTYIIH 69
          LALTY IH
Sbjct: 61 LALTYFIH 63

[Close]

BLAST of CmaCh16G000740 vs. ExPASy Swiss-Prot
Match: O82337 (Arabinogalactan protein 16 OS=Arabidopsis thaliana OX=3702 GN=AGP16 PE=1 SV=1)

HSP 1 Score: 55.1 bits (131), Expect = 3.7e-07
Identity = 31/55 (56.36%), Postives = 42/55 (76.36%), Query Frame = 0


Query: 14 IIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALTYIIH 69
          + + V+ V+L ++ A       APAPAPTSDGT+IDQGIAY+LM++AL LTY+IH
Sbjct: 12 LFSFVFAVILSLAGAQS----LAPAPAPTSDGTSIDQGIAYLLMVVALVLTYLIH 62

[Close]

BLAST of CmaCh16G000740 vs. ExPASy Swiss-Prot
Match: Q9M373 (Arabinogalactan protein 20 OS=Arabidopsis thaliana OX=3702 GN=AGP20 PE=1 SV=1)

HSP 1 Score: 55.1 bits (131), Expect = 3.7e-07
Identity = 31/55 (56.36%), Postives = 41/55 (74.55%), Query Frame = 0


Query: 14 IIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALTYIIH 69
          + A V+ V+ P + A       APAP+PTSDGT+IDQGIAY+LM++AL LTY+IH
Sbjct: 12 LFAFVFAVISPFAGAQS----LAPAPSPTSDGTSIDQGIAYLLMVVALVLTYLIH 62

[Close]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL
Match: A0A6J1HT15 (arabinogalactan peptide 22-like isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC111467520 PE=4 SV=1)

HSP 1 Score: 104.4 bits (259), Expect = 1.9e-19
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  LRACFG+YAVIIA+ YVVMLPVS  AEH+S PAPAPAPTSDGT IDQGIAYILMLLA
Sbjct: 21 MAALRACFGLYAVIIAIFYVVMLPVS-RAEHASSPAPAPAPTSDGTAIDQGIAYILMLLA 80

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 81 LALTYIIH 87

[Close]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL
Match: A0A6J1HU96 (arabinogalactan peptide 22-like isoform X1 OS=Cucurbita maxima OX=3661 GN=LOC111467520 PE=4 SV=1)

HSP 1 Score: 104.4 bits (259), Expect = 1.9e-19
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  LRACFG+YAVIIA+ YVVMLPVS  AEH+S PAPAPAPTSDGT IDQGIAYILMLLA
Sbjct: 26 MAALRACFGLYAVIIAIFYVVMLPVS-RAEHASSPAPAPAPTSDGTAIDQGIAYILMLLA 85

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 86 LALTYIIH 92

[Close]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL
Match: A0A6J1G081 (arabinogalactan peptide 22-like OS=Cucurbita moschata OX=3662 GN=LOC111449506 PE=4 SV=1)

HSP 1 Score: 99.0 bits (245), Expect = 8.2e-18
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M VLRACFGIYAVIIA+ YVVMLPVS  AEH+S  +PAPAPTSDGT IDQGIAYILMLLA
Sbjct: 1  MAVLRACFGIYAVIIAIFYVVMLPVS-RAEHAS--SPAPAPTSDGTAIDQGIAYILMLLA 60

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 61 LALTYIIH 65

[Close]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL
Match: A0A6J1CHE0 (arabinogalactan peptide 22-like OS=Momordica charantia OX=3673 GN=LOC111011447 PE=4 SV=1)

HSP 1 Score: 91.3 bits (225), Expect = 1.7e-15
Identity = 53/68 (77.94%), Postives = 60/68 (88.24%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M V RACFGIYA IIA+++V++LPVS  AEHSS  +PAPAP+SDGTTIDQGIAYILMLLA
Sbjct: 1  MAVSRACFGIYAGIIAILFVIILPVS-RAEHSS--SPAPAPSSDGTTIDQGIAYILMLLA 60

Query: 61 LALTYIIH 69
          L LTYIIH
Sbjct: 61 LVLTYIIH 65

[Close]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL
Match: A0A0A0L7T5 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G355060 PE=4 SV=1)

HSP 1 Score: 89.0 bits (219), Expect = 8.5e-15
Identity = 53/70 (75.71%), Postives = 59/70 (84.29%), Query Frame = 0


Query: 1  MGVLRA-CFGIY-AVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILML 60
          M VLRA CFGIY A++IAV YVV LP+S+A   SS PAPAPAPTSDGT IDQGIAY+LML
Sbjct: 1  MAVLRASCFGIYAALLIAVFYVVALPLSSAQLSSSSPAPAPAPTSDGTAIDQGIAYVLML 60

Query: 61 LALALTYIIH 69
          +AL LTYIIH
Sbjct: 61 VALVLTYIIH 70

[Close]

BLAST of CmaCh16G000740 vs. NCBI nr
Match: KAG6576674.1 (Arabinogalactan protein 22, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 120.9 bits (302), Expect = 4.1e-24
Identity = 66/68 (97.06%), Postives = 66/68 (97.06%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          MGVLR C GIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA
Sbjct: 1  MGVLRDCLGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 61 LALTYIIH 68

[Close]

BLAST of CmaCh16G000740 vs. NCBI nr
Match: XP_022968217.1 (arabinogalactan peptide 22-like isoform X2 [Cucurbita maxima])

HSP 1 Score: 104.4 bits (259), Expect = 4.0e-19
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  LRACFG+YAVIIA+ YVVMLPVS  AEH+S PAPAPAPTSDGT IDQGIAYILMLLA
Sbjct: 21 MAALRACFGLYAVIIAIFYVVMLPVS-RAEHASSPAPAPAPTSDGTAIDQGIAYILMLLA 80

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 81 LALTYIIH 87

[Close]

BLAST of CmaCh16G000740 vs. NCBI nr
Match: XP_022968216.1 (arabinogalactan peptide 22-like isoform X1 [Cucurbita maxima])

HSP 1 Score: 104.4 bits (259), Expect = 4.0e-19
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  LRACFG+YAVIIA+ YVVMLPVS  AEH+S PAPAPAPTSDGT IDQGIAYILMLLA
Sbjct: 26 MAALRACFGLYAVIIAIFYVVMLPVS-RAEHASSPAPAPAPTSDGTAIDQGIAYILMLLA 85

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 86 LALTYIIH 92

[Close]

BLAST of CmaCh16G000740 vs. NCBI nr
Match: XP_022945187.1 (arabinogalactan peptide 22-like [Cucurbita moschata] >XP_023541894.1 arabinogalactan peptide 22-like [Cucurbita pepo subsp. pepo] >KAG7013292.1 Arabinogalactan peptide 22 [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 99.0 bits (245), Expect = 1.7e-17
Identity = 58/68 (85.29%), Postives = 61/68 (89.71%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M VLRACFGIYAVIIA+ YVVMLPVS  AEH+S  +PAPAPTSDGT IDQGIAYILMLLA
Sbjct: 1  MAVLRACFGIYAVIIAIFYVVMLPVS-RAEHAS--SPAPAPTSDGTAIDQGIAYILMLLA 60

Query: 61 LALTYIIH 69
          LALTYIIH
Sbjct: 61 LALTYIIH 65

[Close]

BLAST of CmaCh16G000740 vs. NCBI nr
Match: XP_022140891.1 (arabinogalactan peptide 22-like [Momordica charantia])

HSP 1 Score: 91.3 bits (225), Expect = 3.5e-15
Identity = 53/68 (77.94%), Postives = 60/68 (88.24%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M V RACFGIYA IIA+++V++LPVS  AEHSS  +PAPAP+SDGTTIDQGIAYILMLLA
Sbjct: 1  MAVSRACFGIYAGIIAILFVIILPVS-RAEHSS--SPAPAPSSDGTTIDQGIAYILMLLA 60

Query: 61 LALTYIIH 69
          L LTYIIH
Sbjct: 61 LVLTYIIH 65

[Close]

BLAST of CmaCh16G000740 vs. TAIR 10
Match: AT5G24105.1 (arabinogalactan protein 41 )

HSP 1 Score: 68.9 bits (167), Expect = 1.7e-12
Identity = 36/64 (56.25%), Postives = 51/64 (79.69%), Query Frame = 0


Query: 5  RACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALT 64
          R  FG+ + I+++++ ++LP++    H+   APAPAPTSDGTTIDQGIAY+LML+AL LT
Sbjct: 5  RLFFGV-STIVSIIFAILLPMA----HAQSAAPAPAPTSDGTTIDQGIAYVLMLVALVLT 63

Query: 65 YIIH 69
          Y+IH
Sbjct: 65 YLIH 63

[Close]

BLAST of CmaCh16G000740 vs. TAIR 10
Match: AT5G53250.1 (arabinogalactan protein 22 )

HSP 1 Score: 62.0 bits (149), Expect = 2.1e-10
Identity = 39/68 (57.35%), Postives = 51/68 (75.00%), Query Frame = 0


Query: 1  MGVLRACFGIYAVIIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLA 60
          M  L+    I AV + ++ V++LP+  A  HSS  +PAPAPTSDGT+IDQGIAY+LM++A
Sbjct: 1  MASLKFPLEILAVFV-IISVILLPI--AQSHSS--SPAPAPTSDGTSIDQGIAYVLMMVA 60

Query: 61 LALTYIIH 69
          LALTY IH
Sbjct: 61 LALTYFIH 63

[Close]

BLAST of CmaCh16G000740 vs. TAIR 10
Match: AT2G46330.1 (arabinogalactan protein 16 )

HSP 1 Score: 55.1 bits (131), Expect = 2.6e-08
Identity = 31/55 (56.36%), Postives = 42/55 (76.36%), Query Frame = 0


Query: 14 IIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALTYIIH 69
          + + V+ V+L ++ A       APAPAPTSDGT+IDQGIAY+LM++AL LTY+IH
Sbjct: 12 LFSFVFAVILSLAGAQS----LAPAPAPTSDGTSIDQGIAYLLMVVALVLTYLIH 62

[Close]

BLAST of CmaCh16G000740 vs. TAIR 10
Match: AT3G61640.1 (arabinogalactan protein 20 )

HSP 1 Score: 55.1 bits (131), Expect = 2.6e-08
Identity = 31/55 (56.36%), Postives = 41/55 (74.55%), Query Frame = 0


Query: 14 IIAVVYVVMLPVSAAAEHSSFPAPAPAPTSDGTTIDQGIAYILMLLALALTYIIH 69
          + A V+ V+ P + A       APAP+PTSDGT+IDQGIAY+LM++AL LTY+IH
Sbjct: 12 LFAFVFAVISPFAGAQS----LAPAPSPTSDGTSIDQGIAYLLMVVALVLTYLIH 62

The following BLAST results are available for this feature:

BLAST of CmaCh16G000740 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q8L9T8	2.5e-11	56.25	Arabinogalactan protein 41 OS=Arabidopsis thaliana OX=3702 GN=AGP41 PE=1 SV=1	[more]
Q9FK16	3.0e-09	57.35	Arabinogalactan protein 22 OS=Arabidopsis thaliana OX=3702 GN=AGP22 PE=1 SV=1	[more]
O82337	3.7e-07	56.36	Arabinogalactan protein 16 OS=Arabidopsis thaliana OX=3702 GN=AGP16 PE=1 SV=1	[more]
Q9M373	3.7e-07	56.36	Arabinogalactan protein 20 OS=Arabidopsis thaliana OX=3702 GN=AGP20 PE=1 SV=1	[more]

BLAST of CmaCh16G000740 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A6J1HT15	1.9e-19	85.29	arabinogalactan peptide 22-like isoform X2 OS=Cucurbita maxima OX=3661 GN=LOC111...	[more]
A0A6J1HU96	1.9e-19	85.29	arabinogalactan peptide 22-like isoform X1 OS=Cucurbita maxima OX=3661 GN=LOC111...	[more]
A0A6J1G081	8.2e-18	85.29	arabinogalactan peptide 22-like OS=Cucurbita moschata OX=3662 GN=LOC111449506 PE...	[more]
A0A6J1CHE0	1.7e-15	77.94	arabinogalactan peptide 22-like OS=Momordica charantia OX=3673 GN=LOC111011447 P...	[more]
A0A0A0L7T5	8.5e-15	75.71	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G355060 PE=4 SV=1	[more]

BLAST of CmaCh16G000740 vs. NCBI nr


Match Name	E-value	Identity	Description
KAG6576674.1	4.1e-24	97.06	Arabinogalactan protein 22, partial [Cucurbita argyrosperma subsp. sororia]	[more]
XP_022968217.1	4.0e-19	85.29	arabinogalactan peptide 22-like isoform X2 [Cucurbita maxima]	[more]
XP_022968216.1	4.0e-19	85.29	arabinogalactan peptide 22-like isoform X1 [Cucurbita maxima]	[more]
XP_022945187.1	1.7e-17	85.29	arabinogalactan peptide 22-like [Cucurbita moschata] >XP_023541894.1 arabinogala...	[more]
XP_022140891.1	3.5e-15	77.94	arabinogalactan peptide 22-like [Momordica charantia]	[more]

BLAST of CmaCh16G000740 vs. TAIR 10


Match Name	E-value	Identity	Description
AT5G24105.1	1.7e-12	56.25	arabinogalactan protein 41	[more]
AT5G53250.1	2.1e-10	57.35	arabinogalactan protein 22	[more]
AT2G46330.1	2.6e-08	56.36	arabinogalactan protein 16	[more]
AT3G61640.1	2.6e-08	56.36	arabinogalactan protein 20	[more]

InterPro

Analysis Name: InterPro Annotations of Cucurbita maxima (Rimu) v1.1
Date Performed: 2021-10-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR009424	Arabinogalactan protein 16/20/22/41	PFAM	PF06376	AGP	coord: 36..68 e-value: 2.6E-18 score: 65.6
IPR009424	Arabinogalactan protein 16/20/22/41	PANTHER	PTHR33374	ARABINOGALACTAN PROTEIN 20	coord: 1..68
None	No IPR available	PANTHER	PTHR33374:SF38	ARABINOGALACTAN PROTEIN 41	coord: 1..68

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CmaCh16G000740.1	CmaCh16G000740.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016021	integral component of membrane