CmaCh07G010540 (gene) Cucurbita maxima (Rimu) v1.1

Overview
NameCmaCh07G010540
Typegene
OrganismCucurbita maxima (Cucurbita maxima (Rimu) v1.1)
DescriptionVacuolar cation/proton exchanger
LocationCma_Chr07: 5607832 .. 5609644 (-)
RNA-Seq ExpressionCmaCh07G010540
SyntenyCmaCh07G010540
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGCTGTCATTTCTGTGCCATTTATTGCCGTTATTCTTTGGGTACGCCGCCACCACCTCCACCGTTGCAGCCGCCGCCTCCACCCTCCACCTGTCCAGAGCCAGCAGCATCGTTATGCTCTCGGCTTACATTGCTTACTTGGTCTTCCAACTCTGGACTCACCGCCAATTATTTGAAGCCCAGGTAAGATTATAATACACATTAAAATCCTTAAAAATAAAATAAAATTATTTTTAATTTGATTTTTGAAAAATTAGGAGGATGAAAACGACGACGTACCAGTAGAAGAGGCAGTTATTGGATTCTGGAGTGCATTTGCATGGCTTGTAGGAATGACACTCCTGAATGCTTTGCTGTCGGAATACGTGTCAACACAATTGAGGTAAAACTTAGATGTATATATTCAAAGCCTTTTTTAACCTAAAGTTTTTATGAAATATTGTAACTTATATTATAAATATTATAACCTAAGTTCAACACAATAAGAATAATAAGACATTTTCTAAATACTTTATTTTTAAATTATCTAAATTATTTTACTAAAATAAATATACAATGAGTTCATACAATTATTGCGTGGGCCAATGATGATATTTGAACTCAAAATTGACATTTTCATTTGTCGGTGAGTTTCTTCGGTATAATCTTGCTCCCTATCGTCGGGAATGCAGCCGAACACGCCGGAGCTATCATCTTTGCCTTAAAAAATAAGTTGGTAAGCTTGTCGTTTATCATTCCAATTAACGTAAGACAACAAATAGAAATCGATATAAATGTTTGTTTTTTGTTTGAGGACATAAGTTTGGGGGTTGCTTTGGGGTCAGCAACACAAATTGCACTTTTTGTGGTAAGAATGTGTAATTAATGAAGATTTGAAACCCTATAACAATTCTATTTGGAACCCTAGAAAAGGTTGAAATATCAGGAACTGACCCCAAAAGAATGGGTAATTAATTGCAGATTCCAATGTGTGTGATCGTTGCTTGGACAATGGGAGTGGATATGGATCTAAATTTCAACCTCATGGAAACGGCGTCGCTTGGATTAGCCATTATTACCACAGCCTTCGCCTTACAAGATGGAACCTCTCACTATATTAAAGGCCTTGTTCTTCTGTTATGCTATGTTATTACTGCGGCTTGTTTCTTTGTCTCCAACGCTCTTCGAAAGTCTATTTCACGTAAGCTAAGGAATCTCGGTTGGTTTAGTTTCTATTTGAATTAGATAGAACTTATGAGTGTTCGTATGACTCGAGAATCCGACCAATCTAGACTATCCAACCCAAATCGTAAAGTTGGGTTGGATTAAATTTTTAGAAAATCGAAAAATTTAGATCGGTTGGTAGGTGGGGTTTTTTTTTTTGGGTGACTAATAAGAAAATAGGGTTATAACTCAAACCTACTTTTTAGATTTTTACGAAGATTAAGAATATTTGACGTTTACAACTTATGTTAGTGATATATTGTGAGTTGTGAACGTTTGATATTTGGATTTTATGAGATTTTAGTTTAGGGTTTAGGGTAACTCGATAACCCAACTTAACTCAACCCGACCTACGTGAATTTCAAGTTAGTTCAAAAGATTTTCTCAACTCAACTCAATCAACACGAACACACTCATAGAAAAACTTGTTTCGAAACCTGAATTTGTCTCGTTTGTATTTGGATAGTATAGAGATTGAGCACGTGTTCGAACTTTAAGTGCTTTTATTGATCAAGTAGTTAGAATTATCTTTCGATGGGAAATTATAATAATTAACAATATTCCTAATGTCTTTTTTTTTTTTTTTTTTTTCTTTCTTCAAAGTTGGTAA

mRNA sequence

ATGCTGTCATTTCTGTGCCATTTATTGCCGTTATTCTTTGGGTACGCCGCCACCACCTCCACCGTTGCAGCCGCCGCCTCCACCCTCCACCTGTCCAGAGCCAGCAGCATCGTTATGCTCTCGGCTTACATTGCTTACTTGGTCTTCCAACTCTGGACTCACCGCCAATTATTTGAAGCCCAGGAGGATGAAAACGACGACGTACCAGTAGAAGAGGCAGTTATTGGATTCTGGAGTGCATTTGCATGGCTTGTAGGAATGACACTCCTGAATGCTTTGCTGTCGGAATACGTGTCAACACAATTGAGTTTGGGGGTTGCTTTGGGGTCAGCAACACAAATTGCACTTTTTGTGATTCCAATGTGTGTGATCGTTGCTTGGACAATGGGAGTGGATATGGATCTAAATTTCAACCTCATGGAAACGGCGTCGCTTGGATTAGCCATTATTACCACAGCCTTCGCCTTACAAGATGGAACCTCTCACTATATTAAAGGCCTTGTTCTTCTGTTATGCTATGTTATTACTGCGGCTTGTTTCTTTGTCTCCAACGCTCTTCGAAATTGGTAA

Coding sequence (CDS)

ATGCTGTCATTTCTGTGCCATTTATTGCCGTTATTCTTTGGGTACGCCGCCACCACCTCCACCGTTGCAGCCGCCGCCTCCACCCTCCACCTGTCCAGAGCCAGCAGCATCGTTATGCTCTCGGCTTACATTGCTTACTTGGTCTTCCAACTCTGGACTCACCGCCAATTATTTGAAGCCCAGGAGGATGAAAACGACGACGTACCAGTAGAAGAGGCAGTTATTGGATTCTGGAGTGCATTTGCATGGCTTGTAGGAATGACACTCCTGAATGCTTTGCTGTCGGAATACGTGTCAACACAATTGAGTTTGGGGGTTGCTTTGGGGTCAGCAACACAAATTGCACTTTTTGTGATTCCAATGTGTGTGATCGTTGCTTGGACAATGGGAGTGGATATGGATCTAAATTTCAACCTCATGGAAACGGCGTCGCTTGGATTAGCCATTATTACCACAGCCTTCGCCTTACAAGATGGAACCTCTCACTATATTAAAGGCCTTGTTCTTCTGTTATGCTATGTTATTACTGCGGCTTGTTTCTTTGTCTCCAACGCTCTTCGAAATTGGTAA

Protein sequence

MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEAQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYVSTQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNALRNW
Homology
BLAST of CmaCh07G010540 vs. ExPASy Swiss-Prot
Match: Q93Z81 (Vacuolar cation/proton exchanger 3 OS=Arabidopsis thaliana OX=3702 GN=CAX3 PE=1 SV=1)

HSP 1 Score: 221.5 bits (563), Expect = 8.2e-57
Identity = 133/231 (57.58%), Postives = 153/231 (66.23%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAAT--TSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLF 60
           ++  LCHLLPL   YAAT   ST      +L LSR SSIVML AYIAYL+FQLWTHRQLF
Sbjct: 204 LMGLLCHLLPLLLKYAATGEVSTSMINKMSLTLSRTSSIVMLIAYIAYLIFQLWTHRQLF 263

Query: 61  EAQEDE----NDDVPVEEA-VIGFWSAFAWLVGMTLLNALLSEYV--------------- 120
           EAQ+D+    +D+V VEE  VIGFWS FAWLVGMT++ ALLSEYV               
Sbjct: 264 EAQQDDDDAYDDEVSVEETPVIGFWSGFAWLVGMTIVIALLSEYVVDTIEDASDSWGLSV 323

Query: 121 ---------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGV 180
                                         +SLGVALGSATQI+LFV+P+ VIVAW +G+
Sbjct: 324 SFISIILLPIVGNAAEHAGAIIFAFKNKLDISLGVALGSATQISLFVVPLSVIVAWILGI 383

Query: 181 DMDLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
            MDLNFN++ET+SL LAII TAF LQDGTSHY+KGLVLLLCYVI AACFFV
Sbjct: 384 KMDLNFNILETSSLALAIIITAFTLQDGTSHYMKGLVLLLCYVIIAACFFV 434

BLAST of CmaCh07G010540 vs. ExPASy Swiss-Prot
Match: Q39253 (Vacuolar cation/proton exchanger 1 OS=Arabidopsis thaliana OX=3702 GN=CAX1 PE=1 SV=3)

HSP 1 Score: 206.5 bits (524), Expect = 2.7e-52
Identity = 124/229 (54.15%), Postives = 142/229 (62.01%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHL--SRASSIVMLSAYIAYLVFQLWTHRQLF 60
           +L FLCHLLPL  GY       AA  S + L  SR  SIVML +YIAYLVFQLWTHRQLF
Sbjct: 204 LLGFLCHLLPLLVGYLKNGEASAAVLSDMQLSISRGFSIVMLISYIAYLVFQLWTHRQLF 263

Query: 61  EAQEDE---NDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV----------------- 120
           +AQE E   +DDV  E AVI FWS FAWLVGMTL+ ALLSEYV                 
Sbjct: 264 DAQEQEDEYDDDVEQETAVISFWSGFAWLVGMTLVIALLSEYVVATIEEASDKWNLSVSF 323

Query: 121 -------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDM 180
                                       +SLGVALGSATQI LFV+P+ +IVAW +G++M
Sbjct: 324 ISIILLPIVGNAAEHAGAVIFAFKNKLDISLGVALGSATQIGLFVVPLTIIVAWILGINM 383

Query: 181 DLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
           DLNF  +ET  L ++II TAF LQDG+SHY+KGLVLLLCY I A CFFV
Sbjct: 384 DLNFGPLETGCLAVSIIITAFTLQDGSSHYMKGLVLLLCYFIIAICFFV 432

BLAST of CmaCh07G010540 vs. ExPASy Swiss-Prot
Match: Q5TKG3 (Vacuolar cation/proton exchanger 1b OS=Oryza sativa subsp. japonica OX=39947 GN=CAX1b PE=2 SV=1)

HSP 1 Score: 183.7 bits (465), Expect = 1.9e-45
Identity = 112/232 (48.28%), Postives = 143/232 (61.64%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTS--TVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLF 60
           ML+ LCH LPL   YA T+    + +  + LHLSRA SI+ML AY+AYL FQL THRQLF
Sbjct: 203 MLAVLCHSLPLMLRYAVTSGDHAIVSGDAALHLSRACSILMLIAYLAYLFFQLNTHRQLF 262

Query: 61  EAQ---EDENDDVPV---EEAVIGFWSAFAWLVGMTLLNALLSEYV-------------- 120
           E Q   +D++DD+ +   +E V+GF SA  WL  MTLL ALLS YV              
Sbjct: 263 EPQQVEDDDDDDLVIAQDDEPVLGFSSAMIWLALMTLLTALLSGYVVSTIEAASESWELS 322

Query: 121 ----------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMG 180
                                          ++LGV+LGSATQI++FV+P+ VIVAWTMG
Sbjct: 323 VSFISIILLPIVGNAAEHAGAVIFALKNKMDITLGVSLGSATQISMFVVPVSVIVAWTMG 382

Query: 181 VDMDLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
           + MDL+FNL+ET SL LAI+ TAF LQ+G SHY+KGL+L+LCY + + CFFV
Sbjct: 383 IPMDLDFNLLETGSLFLAILVTAFTLQEGESHYLKGLILVLCYAVISVCFFV 434

BLAST of CmaCh07G010540 vs. ExPASy Swiss-Prot
Match: Q769E5 (Vacuolar cation/proton exchanger 1a OS=Oryza sativa subsp. japonica OX=39947 GN=CAX1a PE=1 SV=1)

HSP 1 Score: 172.9 bits (437), Expect = 3.4e-42
Identity = 105/230 (45.65%), Postives = 136/230 (59.13%), Query Frame = 0

Query: 2   LSFLCHLLPLFFGYAATTS----TVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQL 61
           L+ LCH  PL   YA        +  +AA++L LSRA S VML++Y+AYL FQL THRQL
Sbjct: 196 LAVLCHSAPLLLRYAVAAGEHSVSATSAAASLDLSRACSFVMLASYVAYLFFQLKTHRQL 255

Query: 62  FEAQEDENDDV--PVEEAVIGFWSAFAWLVGMTLLNALLSEYV----------------- 121
           FE QE +  D     EE  +GF SA  WL  MT + ++LSEYV                 
Sbjct: 256 FEPQEVDGGDAGDDDEEPALGFASALFWLALMTAVISVLSEYVVGTIEPTSQSWGLSVSF 315

Query: 122 -------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDM 181
                                       ++LGVALGSATQI++FV+P+ V+VAW MGV M
Sbjct: 316 ISIILLPIVGNAAEHAGAIIFALKNKLDITLGVALGSATQISMFVVPLSVLVAWIMGVQM 375

Query: 182 DLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVS 184
           DL+F L+ET SL +A++ TAF LQDGTSHY+KG++LLLCY++  ACFFV+
Sbjct: 376 DLDFKLLETGSLFMAVLVTAFTLQDGTSHYLKGILLLLCYIVIGACFFVA 425

BLAST of CmaCh07G010540 vs. ExPASy Swiss-Prot
Match: Q5KTQ9 (Vacuolar cation/proton exchanger 1c OS=Oryza sativa subsp. japonica OX=39947 GN=CAX1c PE=2 SV=1)

HSP 1 Score: 159.5 bits (402), Expect = 3.8e-38
Identity = 95/233 (40.77%), Postives = 132/233 (56.65%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 60
           +L  LCH+  L   Y ++T     ++S + LSR+ +IVML AY   L+FQL THRQ+FE 
Sbjct: 210 LLGVLCHIATLVSKYTSSTGDSINSSSVMQLSRSCAIVMLIAYFGSLMFQLKTHRQIFEL 269

Query: 61  QEDEND-----DVPVEEAVIGFWSAFAWLVGMTLLNALLSEYVST--------------- 120
           +ED +D     D   +++VIGF SA  WL+GM ++ A+LS YV T               
Sbjct: 270 EEDSSDSSSSEDDATDKSVIGFASAMVWLIGMAVVTAMLSSYVVTTIEEASESMGIPVRF 329

Query: 121 ---------------------------QLSLGVALGSATQIALFVIPMCVIVAWTMGVDM 180
                                       +SLG+ LGSATQI++ V+P+ +IV+W   + M
Sbjct: 330 ISIILLPIVGNAAEHAGAIIFAFKNKIDISLGITLGSATQISMLVVPVILIVSWVNAIPM 389

Query: 181 DLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNAL 187
           DL+FNL+ET SL +A+ITTAF LQD   HY+KGL L+  Y++ A CFFV  AL
Sbjct: 390 DLDFNLLETGSLAMAVITTAFTLQDDKWHYLKGLNLVFSYIVIAVCFFVMKAL 442

BLAST of CmaCh07G010540 vs. ExPASy TrEMBL
Match: A0A6J1EVB6 (Vacuolar cation/proton exchanger OS=Cucurbita moschata OX=3662 GN=LOC111438123 PE=3 SV=1)

HSP 1 Score: 304.3 bits (778), Expect = 3.6e-79
Identity = 174/228 (76.32%), Postives = 177/228 (77.63%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGY-AATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFE 60
           MLSFLCHLLPL FGY AATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQLFE
Sbjct: 190 MLSFLCHLLPLLFGYAAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQLFE 249

Query: 61  AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV--------------------- 120
           AQEDENDDVPVEEAVIGFWSAFAWLVGMTLL ALLSEYV                     
Sbjct: 250 AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSII 309

Query: 121 ---------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNF 180
                                   +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNF
Sbjct: 310 LLPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNF 369

Query: 181 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNA 186
           NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACF+VSNA
Sbjct: 370 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFYVSNA 417

BLAST of CmaCh07G010540 vs. ExPASy TrEMBL
Match: A0A6J1EZV0 (Vacuolar cation/proton exchanger OS=Cucurbita moschata OX=3662 GN=LOC111438123 PE=3 SV=1)

HSP 1 Score: 304.3 bits (778), Expect = 3.6e-79
Identity = 174/228 (76.32%), Postives = 177/228 (77.63%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGY-AATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFE 60
           MLSFLCHLLPL FGY AATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQLFE
Sbjct: 203 MLSFLCHLLPLLFGYAAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQLFE 262

Query: 61  AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV--------------------- 120
           AQEDENDDVPVEEAVIGFWSAFAWLVGMTLL ALLSEYV                     
Sbjct: 263 AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSII 322

Query: 121 ---------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNF 180
                                   +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNF
Sbjct: 323 LLPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNF 382

Query: 181 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNA 186
           NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACF+VSNA
Sbjct: 383 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFYVSNA 430

BLAST of CmaCh07G010540 vs. ExPASy TrEMBL
Match: A0A1S3BNT2 (Vacuolar cation/proton exchanger OS=Cucumis melo OX=3656 GN=LOC103491652 PE=3 SV=1)

HSP 1 Score: 279.6 bits (714), Expect = 9.4e-72
Identity = 159/225 (70.67%), Postives = 169/225 (75.11%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 60
           MLS LCHLLPL FGYAA++++  AAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA
Sbjct: 200 MLSLLCHLLPLLFGYAASSAS-TAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 259

Query: 61  QEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV---------------------- 120
           +E E+DDVP EEAVIGFWSAFAWLVGMTLL ALLSEYV                      
Sbjct: 260 EEGEDDDVPGEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWGLSVSFLSIIL 319

Query: 121 --------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN 180
                                  +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNFN
Sbjct: 320 LPIVGNAAEHAGAIIFAFKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNFN 379

Query: 181 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVS 184
           +MET SLGLAII TAF LQDGTSHYIKGLVLLLCY+I AACFFVS
Sbjct: 380 IMETGSLGLAIIATAFTLQDGTSHYIKGLVLLLCYIIIAACFFVS 423

BLAST of CmaCh07G010540 vs. ExPASy TrEMBL
Match: J7KJQ3 (Vacuolar cation/proton exchanger OS=Cucumis sativus OX=3659 GN=CAX3 PE=2 SV=1)

HSP 1 Score: 278.9 bits (712), Expect = 1.6e-71
Identity = 159/225 (70.67%), Postives = 168/225 (74.67%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 60
           MLS LCHLLPL FGYAA +++  AAASTLHLSRASSIVML+AYIAYLVFQLWTHRQLFEA
Sbjct: 200 MLSLLCHLLPLLFGYAAASAS-TAAASTLHLSRASSIVMLTAYIAYLVFQLWTHRQLFEA 259

Query: 61  QEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV---------------------- 120
           +E E+DDVP EEAVIGFWSAFAWLVGMTL+ ALLSEYV                      
Sbjct: 260 EEGEDDDVPGEEAVIGFWSAFAWLVGMTLVIALLSEYVVNTIEEASTTWGLSVSFLSIIL 319

Query: 121 --------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN 180
                                  +SLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN
Sbjct: 320 LPIVGNAAEHAGAIIFAFKNKLDISLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN 379

Query: 181 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVS 184
           LMET SLGLAII TAF LQDGTSHYIKGLVLLLCY+I AACFFVS
Sbjct: 380 LMETGSLGLAIIATAFTLQDGTSHYIKGLVLLLCYIIIAACFFVS 423

BLAST of CmaCh07G010540 vs. ExPASy TrEMBL
Match: A0A6J1ITD3 (Vacuolar cation/proton exchanger OS=Cucurbita maxima OX=3661 GN=LOC111478234 PE=3 SV=1)

HSP 1 Score: 270.4 bits (690), Expect = 5.7e-69
Identity = 155/227 (68.28%), Postives = 166/227 (73.13%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVA--AAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLF 60
           MLS LCHLLPL FGYAA++++ A  AAASTLHLSRASSIVML+AYIAYLVFQLWTHR LF
Sbjct: 198 MLSLLCHLLPLLFGYAASSASSASTAAASTLHLSRASSIVMLAAYIAYLVFQLWTHRTLF 257

Query: 61  EAQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV-------------------- 120
           E +E E+DDV  EEAVIGFWSAFAWL GMTLL ALLSEYV                    
Sbjct: 258 ETEETEDDDVSGEEAVIGFWSAFAWLAGMTLLIALLSEYVVNTIEEASTTWGLSVSFLSI 317

Query: 121 ----------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLN 180
                                    +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLN
Sbjct: 318 ILLPIVGNAAEHAGAIIFAFKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLN 377

Query: 181 FNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVS 184
           FNLMET SLGLAII TAF LQDGTSHYIKGL+LLLCY+I AACFFVS
Sbjct: 378 FNLMETGSLGLAIIATAFTLQDGTSHYIKGLILLLCYIIIAACFFVS 424

BLAST of CmaCh07G010540 vs. NCBI nr
Match: XP_022931828.1 (vacuolar cation/proton exchanger 3-like isoform X1 [Cucurbita moschata])

HSP 1 Score: 304.3 bits (778), Expect = 7.4e-79
Identity = 174/228 (76.32%), Postives = 177/228 (77.63%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGY-AATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFE 60
           MLSFLCHLLPL FGY AATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQLFE
Sbjct: 203 MLSFLCHLLPLLFGYAAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQLFE 262

Query: 61  AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV--------------------- 120
           AQEDENDDVPVEEAVIGFWSAFAWLVGMTLL ALLSEYV                     
Sbjct: 263 AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSII 322

Query: 121 ---------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNF 180
                                   +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNF
Sbjct: 323 LLPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNF 382

Query: 181 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNA 186
           NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACF+VSNA
Sbjct: 383 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFYVSNA 430

BLAST of CmaCh07G010540 vs. NCBI nr
Match: XP_022931829.1 (vacuolar cation/proton exchanger 3-like isoform X2 [Cucurbita moschata])

HSP 1 Score: 304.3 bits (778), Expect = 7.4e-79
Identity = 174/228 (76.32%), Postives = 177/228 (77.63%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGY-AATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFE 60
           MLSFLCHLLPL FGY AATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQLFE
Sbjct: 190 MLSFLCHLLPLLFGYAAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQLFE 249

Query: 61  AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV--------------------- 120
           AQEDENDDVPVEEAVIGFWSAFAWLVGMTLL ALLSEYV                     
Sbjct: 250 AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSII 309

Query: 121 ---------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNF 180
                                   +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNF
Sbjct: 310 LLPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNF 369

Query: 181 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNA 186
           NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACF+VSNA
Sbjct: 370 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFYVSNA 417

BLAST of CmaCh07G010540 vs. NCBI nr
Match: XP_023517388.1 (vacuolar cation/proton exchanger 3-like isoform X1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 303.1 bits (775), Expect = 1.6e-78
Identity = 172/226 (76.11%), Postives = 174/226 (76.99%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 60
           MLSFLCHLLPL FGYAATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQ FEA
Sbjct: 203 MLSFLCHLLPLLFGYAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQSFEA 262

Query: 61  QEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV---------------------- 120
           QEDENDDVP EEAVIGFWSAFAWLVGMTLL ALLSEYV                      
Sbjct: 263 QEDENDDVPGEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSIIL 322

Query: 121 --------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN 180
                                  +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNFN
Sbjct: 323 LPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNFN 382

Query: 181 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSN 185
           LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACFFVSN
Sbjct: 383 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFFVSN 428

BLAST of CmaCh07G010540 vs. NCBI nr
Match: XP_023517389.1 (vacuolar cation/proton exchanger 3-like isoform X2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 303.1 bits (775), Expect = 1.6e-78
Identity = 172/226 (76.11%), Postives = 174/226 (76.99%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFEA 60
           MLSFLCHLLPL FGYAATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQ FEA
Sbjct: 190 MLSFLCHLLPLLFGYAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQSFEA 249

Query: 61  QEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV---------------------- 120
           QEDENDDVP EEAVIGFWSAFAWLVGMTLL ALLSEYV                      
Sbjct: 250 QEDENDDVPGEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWDLSVSFLSIIL 309

Query: 121 --------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFN 180
                                  +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNFN
Sbjct: 310 LPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNFN 369

Query: 181 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSN 185
           LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACFFVSN
Sbjct: 370 LMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFFVSN 415

BLAST of CmaCh07G010540 vs. NCBI nr
Match: KAG7027400.1 (Vacuolar cation/proton exchanger 1, partial [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 300.8 bits (769), Expect = 8.1e-78
Identity = 173/227 (76.21%), Postives = 175/227 (77.09%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGY-AATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLFE 60
           MLSFLCHLLPL FGY AATTS VAAAASTLHLSRASSIVML AYIAYLVFQLWTHRQLFE
Sbjct: 203 MLSFLCHLLPLLFGYAAATTSAVAAAASTLHLSRASSIVMLLAYIAYLVFQLWTHRQLFE 262

Query: 61  AQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV--------------------- 120
           AQEDENDDVP EEAVIGFWSAFAWLVGMTLL ALLSEYV                     
Sbjct: 263 AQEDENDDVPGEEAVIGFWSAFAWLVGMTLLIALLSEYVVNTIEEASTTWNLSVCFLSII 322

Query: 121 ---------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNF 180
                                   +SLGVALGSATQIALFVIP+CVIVAWTMGVDMDLNF
Sbjct: 323 LLPIVGNAAEHAGAIIFALKNKLDISLGVALGSATQIALFVIPLCVIVAWTMGVDMDLNF 382

Query: 181 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSN 185
           NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVI AACFFVSN
Sbjct: 383 NLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVIIAACFFVSN 429

BLAST of CmaCh07G010540 vs. TAIR 10
Match: AT3G51860.1 (cation exchanger 3 )

HSP 1 Score: 221.5 bits (563), Expect = 5.8e-58
Identity = 133/231 (57.58%), Postives = 153/231 (66.23%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAAT--TSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLF 60
           ++  LCHLLPL   YAAT   ST      +L LSR SSIVML AYIAYL+FQLWTHRQLF
Sbjct: 204 LMGLLCHLLPLLLKYAATGEVSTSMINKMSLTLSRTSSIVMLIAYIAYLIFQLWTHRQLF 263

Query: 61  EAQEDE----NDDVPVEEA-VIGFWSAFAWLVGMTLLNALLSEYV--------------- 120
           EAQ+D+    +D+V VEE  VIGFWS FAWLVGMT++ ALLSEYV               
Sbjct: 264 EAQQDDDDAYDDEVSVEETPVIGFWSGFAWLVGMTIVIALLSEYVVDTIEDASDSWGLSV 323

Query: 121 ---------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGV 180
                                         +SLGVALGSATQI+LFV+P+ VIVAW +G+
Sbjct: 324 SFISIILLPIVGNAAEHAGAIIFAFKNKLDISLGVALGSATQISLFVVPLSVIVAWILGI 383

Query: 181 DMDLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
            MDLNFN++ET+SL LAII TAF LQDGTSHY+KGLVLLLCYVI AACFFV
Sbjct: 384 KMDLNFNILETSSLALAIIITAFTLQDGTSHYMKGLVLLLCYVIIAACFFV 434

BLAST of CmaCh07G010540 vs. TAIR 10
Match: AT2G38170.1 (cation exchanger 1 )

HSP 1 Score: 206.5 bits (524), Expect = 1.9e-53
Identity = 124/229 (54.15%), Postives = 142/229 (62.01%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHL--SRASSIVMLSAYIAYLVFQLWTHRQLF 60
           +L FLCHLLPL  GY       AA  S + L  SR  SIVML +YIAYLVFQLWTHRQLF
Sbjct: 204 LLGFLCHLLPLLVGYLKNGEASAAVLSDMQLSISRGFSIVMLISYIAYLVFQLWTHRQLF 263

Query: 61  EAQEDE---NDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV----------------- 120
           +AQE E   +DDV  E AVI FWS FAWLVGMTL+ ALLSEYV                 
Sbjct: 264 DAQEQEDEYDDDVEQETAVISFWSGFAWLVGMTLVIALLSEYVVATIEEASDKWNLSVSF 323

Query: 121 -------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDM 180
                                       +SLGVALGSATQI LFV+P+ +IVAW +G++M
Sbjct: 324 ISIILLPIVGNAAEHAGAVIFAFKNKLDISLGVALGSATQIGLFVVPLTIIVAWILGINM 383

Query: 181 DLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
           DLNF  +ET  L ++II TAF LQDG+SHY+KGLVLLLCY I A CFFV
Sbjct: 384 DLNFGPLETGCLAVSIIITAFTLQDGSSHYMKGLVLLLCYFIIAICFFV 432

BLAST of CmaCh07G010540 vs. TAIR 10
Match: AT2G38170.3 (cation exchanger 1 )

HSP 1 Score: 206.5 bits (524), Expect = 1.9e-53
Identity = 124/229 (54.15%), Postives = 142/229 (62.01%), Query Frame = 0

Query: 1   MLSFLCHLLPLFFGYAATTSTVAAAASTLHL--SRASSIVMLSAYIAYLVFQLWTHRQLF 60
           +L FLCHLLPL  GY       AA  S + L  SR  SIVML +YIAYLVFQLWTHRQLF
Sbjct: 204 LLGFLCHLLPLLVGYLKNGEASAAVLSDMQLSISRGFSIVMLISYIAYLVFQLWTHRQLF 263

Query: 61  EAQEDE---NDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV----------------- 120
           +AQE E   +DDV  E AVI FWS FAWLVGMTL+ ALLSEYV                 
Sbjct: 264 DAQEQEDEYDDDVEQETAVISFWSGFAWLVGMTLVIALLSEYVVATIEEASDKWNLSVSF 323

Query: 121 -------------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDM 180
                                       +SLGVALGSATQI LFV+P+ +IVAW +G++M
Sbjct: 324 ISIILLPIVGNAAEHAGAVIFAFKNKLDISLGVALGSATQIGLFVVPLTIIVAWILGINM 383

Query: 181 DLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFV 183
           DLNF  +ET  L ++II TAF LQDG+SHY+KGLVLLLCY I A CFFV
Sbjct: 384 DLNFGPLETGCLAVSIIITAFTLQDGSSHYMKGLVLLLCYFIIAICFFV 432

BLAST of CmaCh07G010540 vs. TAIR 10
Match: AT5G01490.1 (cation exchanger 4 )

HSP 1 Score: 164.5 bits (415), Expect = 8.5e-41
Identity = 105/235 (44.68%), Postives = 136/235 (57.87%), Query Frame = 0

Query: 2   LSFLCHLLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHR------ 61
           L+ LC  LP+   +          +  + LSRASS VML AY+A+L+F L++        
Sbjct: 206 LALLCQTLPMIMRFTMEAEEY-DGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPP 265

Query: 62  ---QLFEAQEDENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEY-VST----------- 121
              Q  +  +D+  D   E AVIG WSA  WL+ MTLL ALLS+Y VST           
Sbjct: 266 PLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLS 325

Query: 122 ------------------------------QLSLGVALGSATQIALFVIPMCVIVAWTMG 181
                                          ++LG+ALGSATQIALFV+P+ V+VAWTMG
Sbjct: 326 VGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMG 385

Query: 182 VDMDLNFNLMETASLGLAIITTAFALQDGTSHYIKGLVLLLCYVITAACFFVSNA 186
           ++MDLNFNL+ETA   L+I+ T+  LQDGTS+Y+KGLVLLLCYV+ AACFFVSN+
Sbjct: 386 IEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNS 439

BLAST of CmaCh07G010540 vs. TAIR 10
Match: AT1G55730.1 (cation exchanger 5 )

HSP 1 Score: 123.2 bits (308), Expect = 2.2e-28
Identity = 86/222 (38.74%), Postives = 111/222 (50.00%), Query Frame = 0

Query: 8   LLPLFFGYAATTSTVAAAASTLHLSRASSIVMLSAYIAYLVFQLWTHRQLF-----EAQE 67
           L P    Y  T S V A +S L LSR SS +ML AY AYL FQL +    +     E  +
Sbjct: 213 LFPAVLHY--THSEVHAGSSELALSRFSSCIMLVAYAAYLFFQLKSQPSSYTPLTEETNQ 272

Query: 68  DENDDVPVEEAVIGFWSAFAWLVGMTLLNALLSEYV------------------------ 127
           +E      E+  I  W A  WL  +T   +LLS Y+                        
Sbjct: 273 NEETSDDDEDPEISKWEAIIWLSILTAWVSLLSGYLVDAIEGASVSWKIPISFISVILLP 332

Query: 128 ------------------STQLSLGVALGSATQIALFVIPMCVIVAWTMGVDMDLNFNLM 183
                                LSLGVA+GS+ QI++F +P CV++ W MG  MDLNF L 
Sbjct: 333 IVGNAAEHAGAIMFAMKDKLDLSLGVAIGSSIQISMFAVPFCVVIGWMMGAQMDLNFQLF 392

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Q93Z818.2e-5757.58Vacuolar cation/proton exchanger 3 OS=Arabidopsis thaliana OX=3702 GN=CAX3 PE=1 ... [more]
Q392532.7e-5254.15Vacuolar cation/proton exchanger 1 OS=Arabidopsis thaliana OX=3702 GN=CAX1 PE=1 ... [more]
Q5TKG31.9e-4548.28Vacuolar cation/proton exchanger 1b OS=Oryza sativa subsp. japonica OX=39947 GN=... [more]
Q769E53.4e-4245.65Vacuolar cation/proton exchanger 1a OS=Oryza sativa subsp. japonica OX=39947 GN=... [more]
Q5KTQ93.8e-3840.77Vacuolar cation/proton exchanger 1c OS=Oryza sativa subsp. japonica OX=39947 GN=... [more]
Match NameE-valueIdentityDescription
A0A6J1EVB63.6e-7976.32Vacuolar cation/proton exchanger OS=Cucurbita moschata OX=3662 GN=LOC111438123 P... [more]
A0A6J1EZV03.6e-7976.32Vacuolar cation/proton exchanger OS=Cucurbita moschata OX=3662 GN=LOC111438123 P... [more]
A0A1S3BNT29.4e-7270.67Vacuolar cation/proton exchanger OS=Cucumis melo OX=3656 GN=LOC103491652 PE=3 SV... [more]
J7KJQ31.6e-7170.67Vacuolar cation/proton exchanger OS=Cucumis sativus OX=3659 GN=CAX3 PE=2 SV=1[more]
A0A6J1ITD35.7e-6968.28Vacuolar cation/proton exchanger OS=Cucurbita maxima OX=3661 GN=LOC111478234 PE=... [more]
Match NameE-valueIdentityDescription
XP_022931828.17.4e-7976.32vacuolar cation/proton exchanger 3-like isoform X1 [Cucurbita moschata][more]
XP_022931829.17.4e-7976.32vacuolar cation/proton exchanger 3-like isoform X2 [Cucurbita moschata][more]
XP_023517388.11.6e-7876.11vacuolar cation/proton exchanger 3-like isoform X1 [Cucurbita pepo subsp. pepo][more]
XP_023517389.11.6e-7876.11vacuolar cation/proton exchanger 3-like isoform X2 [Cucurbita pepo subsp. pepo][more]
KAG7027400.18.1e-7876.21Vacuolar cation/proton exchanger 1, partial [Cucurbita argyrosperma subsp. argyr... [more]
Match NameE-valueIdentityDescription
AT3G51860.15.8e-5857.58cation exchanger 3 [more]
AT2G38170.11.9e-5354.15cation exchanger 1 [more]
AT2G38170.31.9e-5354.15cation exchanger 1 [more]
AT5G01490.18.5e-4144.68cation exchanger 4 [more]
AT1G55730.12.2e-2838.74cation exchanger 5 [more]
InterPro
Analysis Name: InterPro Annotations of Cucurbita maxima (Rimu) v1.1
Date Performed: 2021-10-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004837Sodium/calcium exchanger membrane regionPFAMPF01699Na_Ca_excoord: 95..178
e-value: 1.4E-7
score: 31.6
IPR044880NCX, central ion-binding domain superfamilyGENE3D1.20.1420.30coord: 2..182
e-value: 1.1E-8
score: 36.8
NoneNo IPR availablePANTHERPTHR31503:SF1VACUOLAR CATION/PROTON EXCHANGER 3coord: 102..186
NoneNo IPR availablePANTHERPTHR31503:SF1VACUOLAR CATION/PROTON EXCHANGER 3coord: 1..99
IPR004713Calcium/proton exchangerPANTHERPTHR31503VACUOLAR CALCIUM ION TRANSPORTERcoord: 102..186
coord: 1..99

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
CmaCh07G010540.1CmaCh07G010540.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0070588 calcium ion transmembrane transport
biological_process GO:0006874 cellular calcium ion homeostasis
biological_process GO:0006812 cation transport
biological_process GO:0055085 transmembrane transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0009705 plant-type vacuole membrane
molecular_function GO:0015369 calcium:proton antiporter activity
molecular_function GO:0008324 cation transmembrane transporter activity