Clc05G03890 (gene) Watermelon (cordophanus) v2

Overview
NameClc05G03890
Typegene
OrganismCitrullus lanatus subsp. cordophanus cv. cordophanus (Watermelon (cordophanus) v2)
DescriptionPPIase cyclophilin-type domain-containing protein
LocationClcChr05: 2777597 .. 2781520 (-)
RNA-Seq ExpressionClc05G03890
SyntenyClc05G03890
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGGCCGCAGGCAAAGTGACGCCGAACGCGGTGTTTGTGCGCTCGCGATCGTTTTCCTTATGGGTGTTTCGTCTTGTATTATGGTGTTCCGGTGCTTAATTGGGGCGATTCGGCCGACTTCCGTCGAGGTTTCTTCTACTTCCGATTTTGTTAACTACGGCGGCGACTTCAAGAGTGGGGAGCACAACGAAGAGTGTTGCCGAGGTATTGAGCACTTGGAGCTGTGGGGTGATGCTGTGAAATGGGGTTCTGATTTTAAGCTCAATTCGTCGAGAGAGTGTTGTTTGGCTTGTAAAGCTATGTGTGATGATCAAAGTGGAGGGTGTTTTTGTGATTCTTGGGTGTTCTGTGGTGACGCTAAGGCTTGCGGACCAATGTTTGGTGAGGTATGGCTTAGGACAGTCACTTTTCTTGTGTTCTGGTTCTCTTTCATTGTTTGGTTTTATGTCAGAAAGTTTATTCTGAGGCCAGTCATGGCAGCCTAAAAAATGAGTATATGGAAGAAGATTAAGTAGGTGTTAAACATATCTACAATGCTGAATTTATTAGGCGTTGTTTGGTAACCATCATGTTTTTTAAAATTAAGCTTGAACATTACTTCAAGTATTGATTTGTATGTTTTGTTGTCCACTTCTTAGTAGTGTTTTCCAAATCAACATGTTTTAGTTTTCTTGTCCTTGAGATTGGTTCATGATCATGTGCATATATATTGGCATTGCAAATTCCAATCAGTCTACTTATTCAGTTTCAAATTTCTCTTCATGGGTTTTTCTGGTTGATATTTGTTGTAAATTGCAAAATGTAGGAACATTCTCAAATTTGATCACTGGATGAGAAGTCAACGTAGTTACAAGCCACTTTGTTTTGTTTAGTTCAGTGAATTTGTTTCATTTTGATTGATTTGAAGATTATATTTATAGTTTTACCTGCGTGCTAGTGCTGGTTGAAGAAACAAAAGGATATGCTGCGCCCCGACCAAAGGGCCTCAGGAGATCAAGTCATGTGGACTTCTGGCCTCATGTTTGGGAAAAATGAGGTACTTTGCATTTACTTTAACCTCATTCAGTCGACATCTAAGGCTCTGTGATCGTATCAAATGTTGTTAACATCGCATATTTTTTATTCGTTCATTGAATTTTTGTTTGATTGCATGTAGTAGGTAGGTGTTTGAATGGATTCAATTTTATGTGAAAATGCGAGAACAGTAGAATGATTCTTTTTGGTCTAAGTTTTAAAAACTGATAGTTTAATCCTCGGCCTTTGATTTGCCAATTGACAGCTGACTAGATTATTGGCATTTCTCTCTTTCTTCCCCTTATCTTCTTCTTTCTCCTTTCCTTCAAACTTCTCTAGTGAGCCCGCTGCCATCCCCTCTACGGGCTTAAAAGGAGCTGGAAATAGATGAGTGGGTGTATATGTTGATCCTAATTCCCCTTTCTTGGTTTTATATGGAGTGATTTTAAACTATGAGACTCCATTGATTGAGTAGTAATATTTATCCTTTTGATCAACCTAATAATGGGAGATGTAAATGAAGAAGTTGAATAGAATATTGTTAAATCAAAAATTTCTGCCCGATCCAGACTTCGTTTGTTTGTATTGTGTTTGAGCGTAGATTAATAAATGGCCTCTCTTTCTTTTCTTCTTTTAAAGGGAATTATTCGCATGGAGACAGAGTATGGGACTTTTCGCATAAAGGTTGGTTGTTTTCTTCATCTTCCAGCAGTTTTCTTTCATGACAATGTCTCAGATTTGTACATCTAAAACTTGTGGGTTGCATGTTTCTATTTCTTCCAATAAAACAATATGAACATTCAACGCCTATTTAATTGGTGGAGTCGATAATGTTGTGTAAATGGCCAAAACTAAAATTATAAATATGCTTTGTTATAGCTTGGCAACCTGTGATGGCTTATAGACTTGTAACCAATGCCATAGTTTAAGAGATAAAAAATCTGGTAGAATTATTTTCGGCTAAATTACTCCTGAACTTTGCCCCTTCGTTTAAGAATAATGTAGATTTTTCAGAAGTTGCAATATTACCCTTGACTTTTCATAAATGTTCCAAAATTATCATTGGAGTCAAAATTTATTAGAATGTTGGACAAAAATTGGAACCTAGCCTTGCACGGTAGTGAGCTATAACATTGATTGGGATCCCCTTTTTTTTCTATATATTTATTTTAGTGAAAGATTTAGCATTTTTATTTTTTTGCCTGTCACTTGGTGCAAGCTGAGAATTTCTTTCAGCAAATTATAAATTAATACCAATGGCATTAGTTAATTATGACTCTATCTGGTAACTATTTAATTTTTTATTTTTGTTTTTCAAAATACCACCTCCATCGATTAGTTTCTATGATTTGTTGTTTACCAGTTAGAAGTGTTTCAAAATCAAACTCTGAATTTTGAAAACTCTGAATTTGTTTTTTTTTTTTTTTCTTTTTGGAAATTGGCTAATAATTCAAATATTTACATAGGAACTTTGAAAACTATGAGTAAGAAATTGGAAAAAAACTATCATAATTTTCTAAAACAAAAAACTAAATGGTTACTATACGATGCCTCAGTAATCACTAATACTCCCTCCTTATTTTCTTTCTACTGCCTACAAAATGAAGTATTTTCTCATTAAAATGTTCTGTTCAACACCTTTCTGGCTTTCTCTACCTGAGGCTTTCTTCTTTTTTTGGAAATGAAATTTTATCATCTTGCAGTAGGTATGACTTTAAGAAATTTCATTTTAGATTTATCTCCCCTCTCTGGTTTCTTTTACTTGTATTTTATGCAGCATACATCAACCAGAGGAAATATAGTAAGGAGTATAAAATTGATATTTGACTCTCTCTCTCCCAGCTTTTTCCTGCCTGCGCTCCTCATTCTGTGAACTTTCTTCTTGAGCTCTTGGCATTGCGTTCTTGTGTTGGTTGCCAATTTCATCGGGCTGAAAGTCGTGGAAGCTTCTGGTTTTCCAATGGGGATCATGTTGAAAATGTAAGCCTACCGGGCTCTACTTTTAAATAGCTTCTTATCATCAATAAGATCACTGTGATCCAAACTCATTATCACTGCCCTAAGACATCTATACATCAGGTTTAAGTAATCACTTCACTATGCTGCGTATGTAACTCAAAATTTAAAATGGGCTTAAATGAATGATTTTCTAGTTTTTTGATGGTTACATCTGAGAAATGACAACGCGATAGGAATGGTATTAGCCATTAGAGGTATGGTGTATTCTTTAGTATTTATGTATTTGGGTTCTATCAATTGGTTTAAATGATAGGAATTGTATGTTAGTAATTTGTTAGAGAGTTTGTTGTACTTGTTGGTTATAAATAGAGGGGCAGGTGAACGAAGAAGATATACAATATTTTGGTGAGTGAATTAGGACTTGATCTCAAGATTGGAAGGGTCCAAATACCTTAAATTACTTGATTTATCTTGTATATTGATTATCGTTTATCTTTCAAGATATTTGGGTTCTCTTTATGTCAATACCCAACCCAAACATTTTCTAATGGAGCAAATGGTTGAATGAAACTTAGCTATAATGTATTATATTTTCCCATTCTTGTGTGCTTTTATAGGCTGCTTATGGTCCTCCTTTTGCTCTAATCCAAGGAACTCTTGAAGCACATGGAACCATATTCAAGAAGAATCCAAAGGAAGATTGTCCAACTATTAGAAGAGGATCAGTTGCTTGGGTTGGTTCTGGCCCGGAATTCTTTATCAGCCTCGCCAACCATGACGAATGGCGTGGGGCGTACACCGTGTTCGGTTCTGTTCTTCCCGAAGACATGGAAATGGTGGAAAAAATAGCACAGCTTCCAACAAAATCGGAGGTTTGGCATAACATAAATGTCTCTGTTTTGGAAAAACCTTTTCCTTTTCGGTTAAAAAGAATGAATACTGAACTATAG

mRNA sequence

ATGGGCCGCAGGCAAAGTGACGCCGAACGCGGTGTTTGTGCGCTCGCGATCGTTTTCCTTATGGGTGTTTCGTCTTGTATTATGGTGTTCCGGTGCTTAATTGGGGCGATTCGGCCGACTTCCGTCGAGGTTTCTTCTACTTCCGATTTTGTTAACTACGGCGGCGACTTCAAGAGTGGGGAGCACAACGAAGAGTGTTGCCGAGGTATTGAGCACTTGGAGCTGTGGGGTGATGCTGTGAAATGGGGTTCTGATTTTAAGCTCAATTCGTCGAGAGAGTGTTGTTTGGCTTGTAAAGCTATGTGTGATGATCAAAGTGGAGGGTGTTTTTGTGATTCTTGGGTGTTCTGTGGTGACGCTAAGGCTTGCGGACCAATGTTTGGTGAGTGCTGGTTGAAGAAACAAAAGGATATGCTGCGCCCCGACCAAAGGGCCTCAGGAGATCAAGTCATGTGGACTTCTGGCCTCATGTTTGGGAAAAATGAGGGAATTATTCGCATGGAGACAGAGTATGGGACTTTTCGCATAAAGCTTTTTCCTGCCTGCGCTCCTCATTCTGTGAACTTTCTTCTTGAGCTCTTGGCATTGCGTTCTTGTGTTGGTTGCCAATTTCATCGGGCTGAAAGTCGTGGAAGCTTCTGGTTTTCCAATGGGGATCATGTTGAAAATGCTGCTTATGGTCCTCCTTTTGCTCTAATCCAAGGAACTCTTGAAGCACATGGAACCATATTCAAGAAGAATCCAAAGGAAGATTGTCCAACTATTAGAAGAGGATCAGTTGCTTGGGTTGGTTCTGGCCCGGAATTCTTTATCAGCCTCGCCAACCATGACGAATGGCGTGGGGCGTACACCGTGTTCGGTTCTGTTCTTCCCGAAGACATGGAAATGGTGGAAAAAATAGCACAGCTTCCAACAAAATCGGAGGTTTGGCATAACATAAATGTCTCTGTTTTGGAAAAACCTTTTCCTTTTCGGTTAAAAAGAATGAATACTGAACTATAG

Coding sequence (CDS)

ATGGGCCGCAGGCAAAGTGACGCCGAACGCGGTGTTTGTGCGCTCGCGATCGTTTTCCTTATGGGTGTTTCGTCTTGTATTATGGTGTTCCGGTGCTTAATTGGGGCGATTCGGCCGACTTCCGTCGAGGTTTCTTCTACTTCCGATTTTGTTAACTACGGCGGCGACTTCAAGAGTGGGGAGCACAACGAAGAGTGTTGCCGAGGTATTGAGCACTTGGAGCTGTGGGGTGATGCTGTGAAATGGGGTTCTGATTTTAAGCTCAATTCGTCGAGAGAGTGTTGTTTGGCTTGTAAAGCTATGTGTGATGATCAAAGTGGAGGGTGTTTTTGTGATTCTTGGGTGTTCTGTGGTGACGCTAAGGCTTGCGGACCAATGTTTGGTGAGTGCTGGTTGAAGAAACAAAAGGATATGCTGCGCCCCGACCAAAGGGCCTCAGGAGATCAAGTCATGTGGACTTCTGGCCTCATGTTTGGGAAAAATGAGGGAATTATTCGCATGGAGACAGAGTATGGGACTTTTCGCATAAAGCTTTTTCCTGCCTGCGCTCCTCATTCTGTGAACTTTCTTCTTGAGCTCTTGGCATTGCGTTCTTGTGTTGGTTGCCAATTTCATCGGGCTGAAAGTCGTGGAAGCTTCTGGTTTTCCAATGGGGATCATGTTGAAAATGCTGCTTATGGTCCTCCTTTTGCTCTAATCCAAGGAACTCTTGAAGCACATGGAACCATATTCAAGAAGAATCCAAAGGAAGATTGTCCAACTATTAGAAGAGGATCAGTTGCTTGGGTTGGTTCTGGCCCGGAATTCTTTATCAGCCTCGCCAACCATGACGAATGGCGTGGGGCGTACACCGTGTTCGGTTCTGTTCTTCCCGAAGACATGGAAATGGTGGAAAAAATAGCACAGCTTCCAACAAAATCGGAGGTTTGGCATAACATAAATGTCTCTGTTTTGGAAAAACCTTTTCCTTTTCGGTTAAAAAGAATGAATACTGAACTATAG

Protein sequence

MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSGEHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDAKACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFPACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAHGTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKIAQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL
Homology
BLAST of Clc05G03890 vs. NCBI nr
Match: XP_038895640.1 (uncharacterized protein LOC120083824 isoform X1 [Benincasa hispida])

HSP 1 Score: 646.4 bits (1666), Expect = 1.4e-181
Identity = 299/333 (89.79%), Postives = 316/333 (94.89%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDA+RGVCALAI+FL+G+SSCIMV+RCLIG IRPTSVEVSSTSDFVN GG FKSG
Sbjct: 1   MGRRQSDAKRGVCALAILFLIGISSCIMVYRCLIGPIRPTSVEVSSTSDFVNNGGFFKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           E++EECCRGI+HLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQ G C CDSWVFCGDA
Sbjct: 61  ENSEECCRGIDHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQIGRCLCDSWVFCGDA 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           KACGP FGECWLKKQKD+L PDQRASGDQVMWTSGLMFGKNEGII +ETEYG+FRIKLFP
Sbjct: 121 KACGPNFGECWLKKQKDILSPDQRASGDQVMWTSGLMFGKNEGIISIETEYGSFRIKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
           ACAPHSVNF+LELLALRSCVGCQFHRAESRGS WFS+GDHV+NA YGPPFALIQGTLEAH
Sbjct: 181 ACAPHSVNFILELLALRSCVGCQFHRAESRGSLWFSDGDHVKNAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G +FKKNPKEDCPTIR+GSVAWVGSGPEFFISLANHDEWR AYTVFGSVLPEDMEMVEKI
Sbjct: 241 GIMFKKNPKEDCPTIRKGSVAWVGSGPEFFISLANHDEWRKAYTVFGSVLPEDMEMVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPT  EVWHNINVSVLEKP PF LKR+NTEL
Sbjct: 301 AQLPTNLEVWHNINVSVLEKPIPFGLKRLNTEL 333

BLAST of Clc05G03890 vs. NCBI nr
Match: XP_031739030.1 (uncharacterized protein LOC101208677 [Cucumis sativus] >KGN56703.1 hypothetical protein Csa_009779 [Cucumis sativus])

HSP 1 Score: 633.3 bits (1632), Expect = 1.2e-177
Identity = 292/332 (87.95%), Postives = 309/332 (93.07%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDA RGVCAL IVFLMG+SSC MV+RCLIG+IRPTSVEVSSTSDFVN GG FKSG
Sbjct: 1   MGRRQSDAVRGVCALTIVFLMGISSCFMVYRCLIGSIRPTSVEVSSTSDFVNNGGVFKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECCRGI+HLELWGDAVKWGSDFKLNSSRECCLACKAMCD  SG C+CDSWVFCGD+
Sbjct: 61  EHNEECCRGIDHLELWGDAVKWGSDFKLNSSRECCLACKAMCDGHSGLCWCDSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           KACGP FGECWLKKQKD+L PD RASGDQVMWTSGLMFGK EGIIRMETEYG+FRIKLFP
Sbjct: 121 KACGPHFGECWLKKQKDILSPDIRASGDQVMWTSGLMFGKTEGIIRMETEYGSFRIKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLAL S VGCQFHRAESRG+FWFSNGDH++NA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLALSSYVGCQFHRAESRGTFWFSNGDHIDNAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G IFK+NPKEDCP IRRGS+AWVGSGPEFFISLANHDEWR AYTVFGS+LPEDMEMVEKI
Sbjct: 241 GVIFKENPKEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYTVFGSILPEDMEMVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTE 333
           AQLPTKSE W+NINVSVLEKP PFRLKR  T+
Sbjct: 301 AQLPTKSENWYNINVSVLEKPIPFRLKRTKTD 332

BLAST of Clc05G03890 vs. NCBI nr
Match: KAA0049126.1 (Peptidyl-prolyl cis-trans isomerase-like 3 [Cucumis melo var. makuwa])

HSP 1 Score: 623.2 bits (1606), Expect = 1.3e-174
Identity = 290/333 (87.09%), Postives = 305/333 (91.59%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQ DA RGVCALAIVFLMG+SSC MV+RCLIG+IRPTSVEVSS SDFVN GG  KSG
Sbjct: 1   MGRRQRDAVRGVCALAIVFLMGISSCFMVYRCLIGSIRPTSVEVSSISDFVNDGGVLKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECC GI+HLELWGDAVKWGSDFKL+SSRECCLACKAMCDDQSG C C+SWVFCGD+
Sbjct: 61  EHNEECCGGIDHLELWGDAVKWGSDFKLSSSRECCLACKAMCDDQSGLCRCNSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           KACGP FGECWLKKQKD+L PD RASGDQVMWTSGLMFGK EGIIRMETEYG+FRIKLFP
Sbjct: 121 KACGPHFGECWLKKQKDILSPDIRASGDQVMWTSGLMFGKIEGIIRMETEYGSFRIKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLA  SC+GCQFHRAES GSFWFSNGDH++NA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLASSSCIGCQFHRAESCGSFWFSNGDHIDNAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G +FKK P EDCP IRRGS+AWVGSGPEFFISLANHDEWR AYTVFGSVLPEDMEMVEKI
Sbjct: 241 GVMFKKKPWEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYTVFGSVLPEDMEMVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPTKSE WHNINVSVLEKP PFRLKR  TEL
Sbjct: 301 AQLPTKSENWHNINVSVLEKPIPFRLKRTKTEL 333

BLAST of Clc05G03890 vs. NCBI nr
Match: TYK17437.1 (Peptidyl-prolyl cis-trans isomerase-like 3 [Cucumis melo var. makuwa])

HSP 1 Score: 577.8 bits (1488), Expect = 6.1e-161
Identity = 277/349 (79.37%), Postives = 292/349 (83.67%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQ DA RGVCALAIVFLMG+SSC MV+RCLIG+IRPTSVEVSS SDFVN GG  KSG
Sbjct: 1   MGRRQRDAVRGVCALAIVFLMGISSCFMVYRCLIGSIRPTSVEVSSISDFVNDGGVLKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECC GI+HLELWGDAVKWGSDFKL+SSRECCLACKAMCDDQSG C C+SWVFCGD+
Sbjct: 61  EHNEECCGGIDHLELWGDAVKWGSDFKLSSSRECCLACKAMCDDQSGLCRCNSWVFCGDS 120

Query: 121 KACGPMFGE----------------CWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGI 180
           KACGP FGE                CWLKKQKD+L PD RASGDQVMWTSGLMFGK    
Sbjct: 121 KACGPHFGEPKGCVYGRTLILPACQCWLKKQKDILSPDIRASGDQVMWTSGLMFGK---- 180

Query: 181 IRMETEYGTFRIKLFPACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENA 240
                      I+LFP CAPHSVNF+LELLA  SC+GCQFHRAESRGSFWFSNGDH++NA
Sbjct: 181 -----------IELFPDCAPHSVNFILELLASSSCIGCQFHRAESRGSFWFSNGDHIDNA 240

Query: 241 AYGPPFALIQGTLEAHGTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYT 300
            YGPPFALIQGTLEAHG +FKK P EDCP IRRGS+AWVGSGPEFFISLANHDEWR AYT
Sbjct: 241 PYGPPFALIQGTLEAHGVMFKKKPWEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYT 300

Query: 301 VFGSVLPEDMEMVEKIAQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           VFGSVLPEDMEMVEKIAQLPTKSE WHNINVSVLEKP PFRLKR  TEL
Sbjct: 301 VFGSVLPEDMEMVEKIAQLPTKSENWHNINVSVLEKPIPFRLKRTKTEL 334

BLAST of Clc05G03890 vs. NCBI nr
Match: XP_022980358.1 (uncharacterized protein LOC111479746 [Cucurbita maxima])

HSP 1 Score: 568.5 bits (1464), Expect = 3.7e-158
Identity = 266/333 (79.88%), Postives = 296/333 (88.89%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDAERGVCALAI+FLMG+SSCIMV+  LIGAIRP++VEVSSTSD V      K+G
Sbjct: 1   MGRRQSDAERGVCALAIIFLMGISSCIMVYHFLIGAIRPSAVEVSSTSDLV------KNG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EH EECC+G +H+ELWG AVKWGS+FK NSSRECCLACKAMC+DQ G C CDSWVFCGD+
Sbjct: 61  EH-EECCQGTDHVELWGGAVKWGSNFKFNSSRECCLACKAMCEDQRGRCLCDSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           K CG  FGECWLKKQKD++ P++R SG QV WTSGL+FGK +GI+R+ETEYG+FR+KLFP
Sbjct: 121 KICGSRFGECWLKKQKDIMNPERRESGGQVGWTSGLVFGKKQGIVRVETEYGSFRMKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLAL  CVGCQFHRAESRGSFWFSNGDHVENA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLAL-GCVGCQFHRAESRGSFWFSNGDHVENAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G IF++NPKE CPTIRRGSVAWV SGPEFFISLANHDEWR A+TVFGSVLPEDME+VEKI
Sbjct: 241 GIIFEENPKEYCPTIRRGSVAWVDSGPEFFISLANHDEWRKAHTVFGSVLPEDMEIVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPTKSEVW NI+VSVLEKP P +LK M T+L
Sbjct: 301 AQLPTKSEVWQNIDVSVLEKPIPLQLKGMKTDL 325

BLAST of Clc05G03890 vs. ExPASy TrEMBL
Match: A0A0A0L4L1 (PPIase cyclophilin-type domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_3G129600 PE=4 SV=1)

HSP 1 Score: 633.3 bits (1632), Expect = 5.9e-178
Identity = 292/332 (87.95%), Postives = 309/332 (93.07%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDA RGVCAL IVFLMG+SSC MV+RCLIG+IRPTSVEVSSTSDFVN GG FKSG
Sbjct: 1   MGRRQSDAVRGVCALTIVFLMGISSCFMVYRCLIGSIRPTSVEVSSTSDFVNNGGVFKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECCRGI+HLELWGDAVKWGSDFKLNSSRECCLACKAMCD  SG C+CDSWVFCGD+
Sbjct: 61  EHNEECCRGIDHLELWGDAVKWGSDFKLNSSRECCLACKAMCDGHSGLCWCDSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           KACGP FGECWLKKQKD+L PD RASGDQVMWTSGLMFGK EGIIRMETEYG+FRIKLFP
Sbjct: 121 KACGPHFGECWLKKQKDILSPDIRASGDQVMWTSGLMFGKTEGIIRMETEYGSFRIKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLAL S VGCQFHRAESRG+FWFSNGDH++NA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLALSSYVGCQFHRAESRGTFWFSNGDHIDNAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G IFK+NPKEDCP IRRGS+AWVGSGPEFFISLANHDEWR AYTVFGS+LPEDMEMVEKI
Sbjct: 241 GVIFKENPKEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYTVFGSILPEDMEMVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTE 333
           AQLPTKSE W+NINVSVLEKP PFRLKR  T+
Sbjct: 301 AQLPTKSENWYNINVSVLEKPIPFRLKRTKTD 332

BLAST of Clc05G03890 vs. ExPASy TrEMBL
Match: A0A5A7U4D8 (Peptidyl-prolyl cis-trans isomerase-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold171G003570 PE=4 SV=1)

HSP 1 Score: 623.2 bits (1606), Expect = 6.1e-175
Identity = 290/333 (87.09%), Postives = 305/333 (91.59%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQ DA RGVCALAIVFLMG+SSC MV+RCLIG+IRPTSVEVSS SDFVN GG  KSG
Sbjct: 1   MGRRQRDAVRGVCALAIVFLMGISSCFMVYRCLIGSIRPTSVEVSSISDFVNDGGVLKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECC GI+HLELWGDAVKWGSDFKL+SSRECCLACKAMCDDQSG C C+SWVFCGD+
Sbjct: 61  EHNEECCGGIDHLELWGDAVKWGSDFKLSSSRECCLACKAMCDDQSGLCRCNSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           KACGP FGECWLKKQKD+L PD RASGDQVMWTSGLMFGK EGIIRMETEYG+FRIKLFP
Sbjct: 121 KACGPHFGECWLKKQKDILSPDIRASGDQVMWTSGLMFGKIEGIIRMETEYGSFRIKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLA  SC+GCQFHRAES GSFWFSNGDH++NA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLASSSCIGCQFHRAESCGSFWFSNGDHIDNAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G +FKK P EDCP IRRGS+AWVGSGPEFFISLANHDEWR AYTVFGSVLPEDMEMVEKI
Sbjct: 241 GVMFKKKPWEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYTVFGSVLPEDMEMVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPTKSE WHNINVSVLEKP PFRLKR  TEL
Sbjct: 301 AQLPTKSENWHNINVSVLEKPIPFRLKRTKTEL 333

BLAST of Clc05G03890 vs. ExPASy TrEMBL
Match: A0A5D3D0E4 (Peptidyl-prolyl cis-trans isomerase-like 3 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold434G003010 PE=4 SV=1)

HSP 1 Score: 577.8 bits (1488), Expect = 2.9e-161
Identity = 277/349 (79.37%), Postives = 292/349 (83.67%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQ DA RGVCALAIVFLMG+SSC MV+RCLIG+IRPTSVEVSS SDFVN GG  KSG
Sbjct: 1   MGRRQRDAVRGVCALAIVFLMGISSCFMVYRCLIGSIRPTSVEVSSISDFVNDGGVLKSG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EHNEECC GI+HLELWGDAVKWGSDFKL+SSRECCLACKAMCDDQSG C C+SWVFCGD+
Sbjct: 61  EHNEECCGGIDHLELWGDAVKWGSDFKLSSSRECCLACKAMCDDQSGLCRCNSWVFCGDS 120

Query: 121 KACGPMFGE----------------CWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGI 180
           KACGP FGE                CWLKKQKD+L PD RASGDQVMWTSGLMFGK    
Sbjct: 121 KACGPHFGEPKGCVYGRTLILPACQCWLKKQKDILSPDIRASGDQVMWTSGLMFGK---- 180

Query: 181 IRMETEYGTFRIKLFPACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENA 240
                      I+LFP CAPHSVNF+LELLA  SC+GCQFHRAESRGSFWFSNGDH++NA
Sbjct: 181 -----------IELFPDCAPHSVNFILELLASSSCIGCQFHRAESRGSFWFSNGDHIDNA 240

Query: 241 AYGPPFALIQGTLEAHGTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYT 300
            YGPPFALIQGTLEAHG +FKK P EDCP IRRGS+AWVGSGPEFFISLANHDEWR AYT
Sbjct: 241 PYGPPFALIQGTLEAHGVMFKKKPWEDCPAIRRGSIAWVGSGPEFFISLANHDEWRKAYT 300

Query: 301 VFGSVLPEDMEMVEKIAQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           VFGSVLPEDMEMVEKIAQLPTKSE WHNINVSVLEKP PFRLKR  TEL
Sbjct: 301 VFGSVLPEDMEMVEKIAQLPTKSENWHNINVSVLEKPIPFRLKRTKTEL 334

BLAST of Clc05G03890 vs. ExPASy TrEMBL
Match: A0A6J1IZ28 (uncharacterized protein LOC111479746 OS=Cucurbita maxima OX=3661 GN=LOC111479746 PE=4 SV=1)

HSP 1 Score: 568.5 bits (1464), Expect = 1.8e-158
Identity = 266/333 (79.88%), Postives = 296/333 (88.89%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDAERGVCALAI+FLMG+SSCIMV+  LIGAIRP++VEVSSTSD V      K+G
Sbjct: 1   MGRRQSDAERGVCALAIIFLMGISSCIMVYHFLIGAIRPSAVEVSSTSDLV------KNG 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           EH EECC+G +H+ELWG AVKWGS+FK NSSRECCLACKAMC+DQ G C CDSWVFCGD+
Sbjct: 61  EH-EECCQGTDHVELWGGAVKWGSNFKFNSSRECCLACKAMCEDQRGRCLCDSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           K CG  FGECWLKKQKD++ P++R SG QV WTSGL+FGK +GI+R+ETEYG+FR+KLFP
Sbjct: 121 KICGSRFGECWLKKQKDIMNPERRESGGQVGWTSGLVFGKKQGIVRVETEYGSFRMKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLAL  CVGCQFHRAESRGSFWFSNGDHVENA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLAL-GCVGCQFHRAESRGSFWFSNGDHVENAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G IF++NPKE CPTIRRGSVAWV SGPEFFISLANHDEWR A+TVFGSVLPEDME+VEKI
Sbjct: 241 GIIFEENPKEYCPTIRRGSVAWVDSGPEFFISLANHDEWRKAHTVFGSVLPEDMEIVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPTKSEVW NI+VSVLEKP P +LK M T+L
Sbjct: 301 AQLPTKSEVWQNIDVSVLEKPIPLQLKGMKTDL 325

BLAST of Clc05G03890 vs. ExPASy TrEMBL
Match: A0A6J1E8V3 (uncharacterized protein LOC111431919 OS=Cucurbita moschata OX=3662 GN=LOC111431919 PE=4 SV=1)

HSP 1 Score: 564.3 bits (1453), Expect = 3.4e-157
Identity = 261/333 (78.38%), Postives = 292/333 (87.69%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTSVEVSSTSDFVNYGGDFKSG 60
           MGRRQSDAERGVCALAI+FLMG+SSCIMVF  LIGAIRP++VEVSSTSD V         
Sbjct: 1   MGRRQSDAERGVCALAIIFLMGISSCIMVFHFLIGAIRPSAVEVSSTSDLV-------KN 60

Query: 61  EHNEECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFCGDA 120
           E +EECCRG +H+ELWG AVKWG++FK NSSRECCLACKAMC+DQ G C CDSWVFCGD+
Sbjct: 61  EEHEECCRGTDHVELWGGAVKWGANFKFNSSRECCLACKAMCEDQRGRCLCDSWVFCGDS 120

Query: 121 KACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIKLFP 180
           K CG  FGECWLKKQKD++ P++R SG QV WTSGL+FG+ +GI+R+ETEYG+FR+KLFP
Sbjct: 121 KICGSRFGECWLKKQKDIMNPERRESGGQVGWTSGLVFGRKQGIVRVETEYGSFRMKLFP 180

Query: 181 ACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTLEAH 240
            CAPHSVNF+LELLAL  CVGCQFHRAESRGSFWFSNGDHVENA YGPPFALIQGTLEAH
Sbjct: 181 DCAPHSVNFILELLAL-GCVGCQFHRAESRGSFWFSNGDHVENAPYGPPFALIQGTLEAH 240

Query: 241 GTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMVEKI 300
           G +F++NPKE CPTIRRGSVAWV SGPEFFISLANHDEWR A+TVFGSVLPEDME+VEKI
Sbjct: 241 GIVFEENPKEYCPTIRRGSVAWVDSGPEFFISLANHDEWRKAHTVFGSVLPEDMEIVEKI 300

Query: 301 AQLPTKSEVWHNINVSVLEKPFPFRLKRMNTEL 334
           AQLPTKSEVW N++VSVLEKP P +LK M T L
Sbjct: 301 AQLPTKSEVWQNVDVSVLEKPIPLQLKGMKTNL 325

BLAST of Clc05G03890 vs. TAIR 10
Match: AT4G17070.1 (peptidyl-prolyl cis-trans isomerases )

HSP 1 Score: 423.3 bits (1087), Expect = 1.8e-118
Identity = 193/334 (57.78%), Postives = 242/334 (72.46%), Query Frame = 0

Query: 1   MGRRQSDAERGVCALAIVFLMGVSSCIMVFRCLIGAIRPTS--VEVSSTSDFVNYGGDFK 60
           M RR +D E G     ++ L+G+ SC++V+      +RP+     V S   F     D  
Sbjct: 1   MPRRLNDGEPGRFTATVLLLIGLISCVIVYAVFSSVLRPSQDPTLVDSAVRFKEEPRDHD 60

Query: 61  SGEHNE-ECCRGIEHLELWGDAVKWGSDFKLNSSRECCLACKAMCDDQSGGCFCDSWVFC 120
           + E  E  CCRGI++LELWG AVKWG+DFK NSS  CC ACK MC    G C CDSWVFC
Sbjct: 61  ATEDGEGGCCRGIDNLELWGPAVKWGTDFKFNSSDGCCKACKVMCSGNDGPCLCDSWVFC 120

Query: 121 GDAKACGPMFGECWLKKQKDMLRPDQRASGDQVMWTSGLMFGKNEGIIRMETEYGTFRIK 180
           G+ + CG  FGECWLKKQKD+L PD++  G++VMWTSGL+FG+ +GI+  ETE+G   +K
Sbjct: 121 GNKEDCGSKFGECWLKKQKDVLVPDRQGGGEKVMWTSGLIFGQGQGIVGFETEHGVIHVK 180

Query: 181 LFPACAPHSVNFLLELLALRSCVGCQFHRAESRGSFWFSNGDHVENAAYGPPFALIQGTL 240
           L P CAPHSV ++L LL LR C GCQFHRAE+RGS+W S G+HV+NA +GPP+A+IQG L
Sbjct: 181 LHPECAPHSVYYILSLLTLRHCAGCQFHRAENRGSYWDSEGNHVKNAPFGPPYAMIQGIL 240

Query: 241 EAHGTIFKKNPKEDCPTIRRGSVAWVGSGPEFFISLANHDEWRGAYTVFGSVLPEDMEMV 300
           +A G IF   P E CPTI RGSVAWVGSGPEFFISLANH EW+ +YTVFG VLPEDM++V
Sbjct: 241 QAEGNIFTPIPTEHCPTISRGSVAWVGSGPEFFISLANHHEWKQSYTVFGLVLPEDMDVV 300

Query: 301 EKIAQLPTKSEVWHNINVSVLEKPFPFRLKRMNT 332
           E IA LPT+++VW+++NVSVLEKP    ++RM T
Sbjct: 301 ETIAGLPTRADVWNSVNVSVLEKPVSLTVRRMKT 334

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_038895640.11.4e-18189.79uncharacterized protein LOC120083824 isoform X1 [Benincasa hispida][more]
XP_031739030.11.2e-17787.95uncharacterized protein LOC101208677 [Cucumis sativus] >KGN56703.1 hypothetical ... [more]
KAA0049126.11.3e-17487.09Peptidyl-prolyl cis-trans isomerase-like 3 [Cucumis melo var. makuwa][more]
TYK17437.16.1e-16179.37Peptidyl-prolyl cis-trans isomerase-like 3 [Cucumis melo var. makuwa][more]
XP_022980358.13.7e-15879.88uncharacterized protein LOC111479746 [Cucurbita maxima][more]
Match NameE-valueIdentityDescription
Match NameE-valueIdentityDescription
A0A0A0L4L15.9e-17887.95PPIase cyclophilin-type domain-containing protein OS=Cucumis sativus OX=3659 GN=... [more]
A0A5A7U4D86.1e-17587.09Peptidyl-prolyl cis-trans isomerase-like 3 OS=Cucumis melo var. makuwa OX=119469... [more]
A0A5D3D0E42.9e-16179.37Peptidyl-prolyl cis-trans isomerase-like 3 OS=Cucumis melo var. makuwa OX=119469... [more]
A0A6J1IZ281.8e-15879.88uncharacterized protein LOC111479746 OS=Cucurbita maxima OX=3661 GN=LOC111479746... [more]
A0A6J1E8V33.4e-15778.38uncharacterized protein LOC111431919 OS=Cucurbita moschata OX=3662 GN=LOC1114319... [more]
Match NameE-valueIdentityDescription
AT4G17070.11.8e-11857.78peptidyl-prolyl cis-trans isomerases [more]
InterPro
Analysis Name: InterPro Annotations of Watermelon (cordophanus) v2
Date Performed: 2022-01-31
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR029000Cyclophilin-like domain superfamilyGENE3D2.40.100.10coord: 155..320
e-value: 6.7E-21
score: 76.7
IPR029000Cyclophilin-like domain superfamilySUPERFAMILY50891Cyclophilin-likecoord: 151..315
IPR002130Cyclophilin-type peptidyl-prolyl cis-trans isomerase domainPFAMPF00160Pro_isomerasecoord: 165..310
e-value: 4.0E-15
score: 56.4
NoneNo IPR availablePANTHERPTHR46873:SF2PEPTIDYL-PROLYL CIS-TRANS ISOMERASEScoord: 1..331
NoneNo IPR availablePANTHERPTHR46873EXPRESSED PROTEINcoord: 1..331
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..26
score: 6.0

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Clc05G03890.2Clc05G03890.2mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0000413 protein peptidyl-prolyl isomerization
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0003755 peptidyl-prolyl cis-trans isomerase activity