Cla97C09G166550 (gene) Watermelon (97103) v2.5

Overview
NameCla97C09G166550
Typegene
OrganismCitrullus lanatus subsp. vulgaris cv. 97103 (Watermelon (97103) v2.5)
Descriptionarabinogalactan peptide 23-like
LocationCla97Chr09: 3601042 .. 3604406 (+)
RNA-Seq ExpressionCla97C09G166550
SyntenyCla97C09G166550
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptidethree_prime_UTR
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGGAGATCTTGGAAGTGCCGGAAATCGCCATTGAAAGTGAAAGAAATTACTTAAGAGAAGAAAAGGAATGTGTGTGAATTCTGGAAATTGTGAGTCGGTGAAATGAGAGCGTTGTATTCGGAGCTTATTTATAGGGTGGCCGGAAGGCGTGTGGACCCCACCGGGACTAGGCGTCCAATTGCGTGGTGAAAAGTCGCGTGAGATTTGTGGCCACGTGGAATACAAAAAAACTAAAAACTAATTAAATTATTTGTGTTCGCTGCAAATTGTGTTTTTTTTTTTTTTCCTTTCTCAATTTCAATACCGTTGAAAATTGAAGTTAACATATTTATTGAAGAATTTTTTTTTAAATTTTTTTATTTTAAGTGATAAAATTAAAAAATAAAAAATAAATTTAAATTAGTAAATAAATGTTTTATGATTTTTTGAACAAGTTGACATGTCTATTATTTAAATTATATTTATATTAGTAACATTTCGTGATTATCTTTTATGTTTCGTGGATTTTTCTACGATATAATGGAGATTTCGATTCACCTCTAATGTCGATATCAAATCTATGGAAACAAAAAAAATATAGAGATGTTGACGGAAAATTAATACTATGATTCTCACATAATTTTAGAACTTAATTCAACGCTCTATACAGTCGCTAAAATTAACATTTTTTAGTAGTTTAATCTTTTTATTAATGTTACGAATAATATTTTAATCAATTGAATTGTGCTCAAATTGACATTTTGCGTTTAAAGATCATATATCATAGTTATAGTGTCAAATAAATGTCTAAAATTAAATTAACAACAACTTACAAGGACTTGTTAAACATTTTTTTAAAAAGAAGTTATAAATCTATTAGACACAGAACAAAATGTTTAGAAATCTTATGGTTTAAAAAAACAAAAATTAGAGACATGTTCTAGACAACATTGAGATTGAAAAAAAAAAAAGACACAAAGATACAAATAGAGCATCCAACCCCAAATACGACACGAACTCTCCATTAATGATAGAGATAATACAATTATAAAATTTATCCTTCCACCTAAAAGAATCCTTAAGAGATGATGTGAAAGTTGCAACAGAGTAAGCAACTTTATTCTCCTTTCTGAGAGAGAAACAAAAGTATTTAGCATTTGGTGGATACAACAAAAATATCTAATTCAGTAAGTTCAAACTACTTAAAAACTAAGCAAACCAATAAGGTCTACAGCGTTAGACTCCACGCGGTAAGAAAATTTGTTCTTAAAAGATGTTAAAATTGAAATTTAATTGATATGGTTAAAGCTAAATTACTTCATGTTTGTTTAAGAGTGTTGTATTAATTTTTAGCCTTTGTTATTAGTCAAGAATTACTTTGGAAATTAAATCCTCTATGCATTAATTTTAATCGTTGATTTGCTTAATATGACATCTAATGAAGTATACATATGTGTAAAAGTTTTAAAACCATAGGTCTGTTTGTGGGCTGTCGTCTGTTGAAAGGAAAAAAGAAAGGAGGAGCTTGGCGTTTGGGTTGAAGAAGGAAAGAAGAAAACGCGGCGTTTAATTCAAAGGCGGTGGGGGGTAAAACTGAGATTTCACATGTTGGGACTTGGGAGATTGAGGTTGAAGTTGTTCAACCAAAACACACGAAACGGGGAAGTGTGTTCTCATTTCTTGACTTCAAATTCTTATTATTTGTTGTGTGTTACACCTTTCCTTTCTTTTTCTATTTTCCTCCAAAAATTAAATATATATATACATGTTTTAATTTAACCATTGTATTTTAAAATATTACACTTTTAGTCTTTATGTTTTGAATTTTATTTCAATTTGATTTTTAAATGTTCACGGATCACGGATCACGAATTATTTTGAGGAATCAAGAACTTATTCCCGCCAAAATTCTTCTACTCTTCTAGCCTGCCCTGCTTCTATTTGATTAAATAATGTATGACAATAATAGTAAAAAGCTTATATAATTTTAATGTATTTTAATACAAATATTTAAAAAAATAGTTTTTTATTTTTTATTTTTTTACACAGAGACTTGATTTCCAAAGAGGAACGATGTGAAAAAATTACCCCACCCGTTATCATCCCTACCAATAGGTCATGAAATATTCTAATAACTTCGTTTTTTAAATGGTAGAATCCCTTTGACAAATAATAATAATACATTTTGTGTGGAATATATTATAAATTCTTCATTTTTTTAGGGATTTAAAATCAGTAATTATTGCTCTTACAAGTTACAATATATTTATATTTTAATAAACAACAACAAACCCCCAAAATTTTTCATTTAAGTTCGTTTTGTTATGTTCAATGATATAAGGTAGGAGGATTCAAAGTTTAAGTCCATGATGATGGATGCAAACGAACATTTTCATTAAAAGCAAAAAAAAAATTTACTCATAATATAAGACACAATCCAACAAGTTTGACATTAATAATATTGCATAAATTAACAACCATTTAAAGTAATCTTTCTTATTTAAGAGATTCAAATACCCATATCTTACTTGTTACACCAAAAAATATTTGAATCTCCCTCTTCAAAATTGCAATCTAGTATTGAATTCCGTTACGAATTTAATATATAATTATCGATAGTGCTTAATCGTTTACTAAATTATATAGAGGTGTTTAAAAGTATATTATACATATTATGCATTCTTCTGAAAAACGAGATATTATACATAAAACAAAAAATAATTTAAAAGTAGCATTAAAGTGGAAAAGTGAAAGAAAGGAAAAACCAAGTTGTAATTAGTAATATTTTGAATCAGCCCCACTAGCCACAAGCGGGAAAAAAGGGCCGACATAAGACTCGCTCAAACTAGTTATTTAATTTTTAACCAATTAAACAAAACAATACCTTTTTTTTTAAATGAAATTCCAAAATTAGCATCCTGATTTACCTATAAATAATCTCAATTAGCTTAATTGTTCCTCAGGCAGCAATCCAACAATCAGAGGCTTCTTCGGTTCGATCGCTCCATCTCAATCGGAAGTGAGTTTTCTGCCGAAGAAAGCCAATTCAATCTCATCCGCCATGGAAATGAAGAACTTCGCTTGCGCCGCCCTCTTCGCCGCCGCCACCCTCAGCGCCGCCGTTGCTGCCGATGAGTCTCTCTCTCCTGCCGCTGCGCCGGGGCCGAGCAGCGCCGCCTCCGCCGCTCTCCCCTCCCTCGGATCCCTCGTCGGTGCCTCACTTGTTTCCTTCGTTGCCTACTTCTTGAACTGAAGCCCCGCCCCAGAGAGGGAGATTCTAATTGAAATTTTATGTTTACTTTTTTCATTTTTCTTTATGTGTTTGGTTTTTACGAATGTCGATGGATGATGTGATGTGACGTCATATATAAATGAAAATTAAGAA

mRNA sequence

ATGGAGATCTTGGAAGTGCCGGAAATCGCCATTGAAAGTGAAAGAAATTACTTAAGAGAAGAAAAGGAATGGTGGCCGGAAGGCGTGTGGACCCCACCGGGACTAGGCGTCCAATTGCGTGGTGAAAAGTCGCGTCTGTTTGTGGGCTGTCGTCTGTTGAAAGGAAAAAAGAAAGGAGGAGCTTGGCGCAGCAATCCAACAATCAGAGGCTTCTTCGGTTCGATCGCTCCATCTCAATCGGAAGTGAGTTTTCTGCCGAAGAAAGCCAATTCAATCTCATCCGCCATGGAAATGAAGAACTTCGCTTGCGCCGCCCTCTTCGCCGCCGCCACCCTCAGCGCCGCCGTTGCTGCCGATGAGTCTCTCTCTCCTGCCGCTGCGCCGGGGCCGAGCAGCGCCGCCTCCGCCGCTCTCCCCTCCCTCGGATCCCTCGTCGGTGCCTCACTTGTTTCCTTCGTTGCCTACTTCTTGAACTGAAGCCCCGCCCCAGAGAGGGAGATTCTAATTGAAATTTTATGTTTACTTTTTTCATTTTTCTTTATGTGTTTGGTTTTTACGAATGTCGATGGATGATGTGATGTGACGTCATATATAAATGAAAATTAAGAA

Coding sequence (CDS)

ATGGAGATCTTGGAAGTGCCGGAAATCGCCATTGAAAGTGAAAGAAATTACTTAAGAGAAGAAAAGGAATGGTGGCCGGAAGGCGTGTGGACCCCACCGGGACTAGGCGTCCAATTGCGTGGTGAAAAGTCGCGTCTGTTTGTGGGCTGTCGTCTGTTGAAAGGAAAAAAGAAAGGAGGAGCTTGGCGCAGCAATCCAACAATCAGAGGCTTCTTCGGTTCGATCGCTCCATCTCAATCGGAAGTGAGTTTTCTGCCGAAGAAAGCCAATTCAATCTCATCCGCCATGGAAATGAAGAACTTCGCTTGCGCCGCCCTCTTCGCCGCCGCCACCCTCAGCGCCGCCGTTGCTGCCGATGAGTCTCTCTCTCCTGCCGCTGCGCCGGGGCCGAGCAGCGCCGCCTCCGCCGCTCTCCCCTCCCTCGGATCCCTCGTCGGTGCCTCACTTGTTTCCTTCGTTGCCTACTTCTTGAACTGA

Protein sequence

MEILEVPEIAIESERNYLREEKEWWPEGVWTPPGLGVQLRGEKSRLFVGCRLLKGKKKGGAWRSNPTIRGFFGSIAPSQSEVSFLPKKANSISSAMEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAYFLN
Homology
BLAST of Cla97C09G166550 vs. NCBI nr
Match: XP_038899473.1 (arabinogalactan protein 23-like [Benincasa hispida])

HSP 1 Score: 93.2 bits (230), Expect = 2.2e-15
Identity = 56/63 (88.89%), Postives = 60/63 (95.24%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAA +S+AVAADESLSPAAAPGPSSAASAALP+LGSLVGASLV+FVAY
Sbjct: 1   MEMKKIACAALFAAAAVSSAVAADESLSPAAAPGPSSAASAALPALGSLVGASLVTFVAY 60

Query: 156 FLN 159
           FLN
Sbjct: 61  FLN 63

BLAST of Cla97C09G166550 vs. NCBI nr
Match: XP_023528634.1 (arabinogalactan peptide 23 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 90.9 bits (224), Expect = 1.1e-14
Identity = 54/63 (85.71%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMKN ACAALFAAA ++A VA+DESLSPAAAPGPSSAASAALP+LGSL+GASLVSFVAY
Sbjct: 1   MEMKNIACAALFAAAAVTAVVASDESLSPAAAPGPSSAASAALPALGSLIGASLVSFVAY 60

Query: 156 FLN 159
            LN
Sbjct: 61  VLN 63

BLAST of Cla97C09G166550 vs. NCBI nr
Match: XP_023004714.1 (arabinogalactan peptide 23-like [Cucurbita maxima])

HSP 1 Score: 90.9 bits (224), Expect = 1.1e-14
Identity = 54/63 (85.71%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAAT++A VA+DESLSPAAAPGPSSAASAALP+LGSLVGASLVSFVAY
Sbjct: 1   MEMKKIACAALFAAATVTAVVASDESLSPAAAPGPSSAASAALPALGSLVGASLVSFVAY 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. NCBI nr
Match: XP_022960230.1 (arabinogalactan peptide 23-like [Cucurbita moschata])

HSP 1 Score: 90.5 bits (223), Expect = 1.4e-14
Identity = 54/63 (85.71%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAATL+A VA+DESLSPAAAPGPSSAASAALP+LGSLVGASLVSFVA+
Sbjct: 1   MEMKKIACAALFAAATLTAVVASDESLSPAAAPGPSSAASAALPALGSLVGASLVSFVAF 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. NCBI nr
Match: KAG7025661.1 (Arabinogalactan peptide 23, partial [Cucurbita argyrosperma subsp. argyrosperma])

HSP 1 Score: 89.4 bits (220), Expect = 3.1e-14
Identity = 53/63 (84.13%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAAT++A VA+DESLSPAAAPGPSSAASAALP+LGSLVGASLVSFVA+
Sbjct: 1   MEMKKIACAALFAAATVTAVVASDESLSPAAAPGPSSAASAALPALGSLVGASLVSFVAF 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. ExPASy Swiss-Prot
Match: Q8S2W4 (Arabinogalactan protein 23 OS=Arabidopsis thaliana OX=3702 GN=AGP23 PE=1 SV=2)

HSP 1 Score: 65.1 bits (157), Expect = 8.2e-10
Identity = 41/63 (65.08%), Postives = 52/63 (82.54%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  AC  LFAAA+++A +AA+E  +P  APGP+SAASAALP+LGSLVGASLVS  +Y
Sbjct: 1   MEMKKIACGVLFAAASMTAVMAAEEVGAP--APGPASAASAALPALGSLVGASLVSLFSY 60

Query: 156 FLN 159
           +L+
Sbjct: 61  YLH 61

BLAST of Cla97C09G166550 vs. ExPASy TrEMBL
Match: A0A6J1KX42 (arabinogalactan peptide 23-like OS=Cucurbita maxima OX=3661 GN=LOC111497929 PE=4 SV=1)

HSP 1 Score: 90.9 bits (224), Expect = 5.2e-15
Identity = 54/63 (85.71%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAAT++A VA+DESLSPAAAPGPSSAASAALP+LGSLVGASLVSFVAY
Sbjct: 1   MEMKKIACAALFAAATVTAVVASDESLSPAAAPGPSSAASAALPALGSLVGASLVSFVAY 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. ExPASy TrEMBL
Match: A0A6J1H8I1 (arabinogalactan peptide 23-like OS=Cucurbita moschata OX=3662 GN=LOC111461032 PE=4 SV=1)

HSP 1 Score: 90.5 bits (223), Expect = 6.8e-15
Identity = 54/63 (85.71%), Postives = 59/63 (93.65%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAATL+A VA+DESLSPAAAPGPSSAASAALP+LGSLVGASLVSFVA+
Sbjct: 1   MEMKKIACAALFAAATLTAVVASDESLSPAAAPGPSSAASAALPALGSLVGASLVSFVAF 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. ExPASy TrEMBL
Match: A0A6J1F3F5 (arabinogalactan peptide 23-like OS=Cucurbita moschata OX=3662 GN=LOC111439670 PE=4 SV=1)

HSP 1 Score: 87.0 bits (214), Expect = 7.5e-14
Identity = 52/63 (82.54%), Postives = 57/63 (90.48%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  ACAALFAAAT++A VA+DESLSPAAAPGPSSAASA LP+LGSLVGASLVS VAY
Sbjct: 1   MEMKKIACAALFAAATVTAVVASDESLSPAAAPGPSSAASATLPALGSLVGASLVSLVAY 60

Query: 156 FLN 159
           + N
Sbjct: 61  YFN 63

BLAST of Cla97C09G166550 vs. ExPASy TrEMBL
Match: A0A6J1IYE9 (arabinogalactan peptide 23-like OS=Cucurbita maxima OX=3661 GN=LOC111479619 PE=4 SV=1)

HSP 1 Score: 85.1 bits (209), Expect = 2.8e-13
Identity = 51/63 (80.95%), Postives = 56/63 (88.89%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMKN AC ALF AA ++A VA+DES SPAAAPGPSSAASAALP+LGSL+GASLVSFVAY
Sbjct: 1   MEMKNIACTALFTAAAVTAVVASDESHSPAAAPGPSSAASAALPALGSLIGASLVSFVAY 60

Query: 156 FLN 159
            LN
Sbjct: 61  VLN 63

BLAST of Cla97C09G166550 vs. ExPASy TrEMBL
Match: A0A1S3CDX5 (arabinogalactan peptide 23-like OS=Cucumis melo OX=3656 GN=LOC103499912 PE=4 SV=1)

HSP 1 Score: 75.9 bits (185), Expect = 1.7e-10
Identity = 51/64 (79.69%), Postives = 56/64 (87.50%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFV-A 155
           MEMK  ACAALFAAA +SAAVAADES+SPAAAPGPSSAASAALP    ++GAS+VSFV A
Sbjct: 1   MEMKKIACAALFAAAAVSAAVAADESISPAAAPGPSSAASAALP----VLGASVVSFVAA 60

Query: 156 YFLN 159
           YFLN
Sbjct: 61  YFLN 60

BLAST of Cla97C09G166550 vs. TAIR 10
Match: AT3G57690.1 (arabinogalactan protein 23 )

HSP 1 Score: 65.1 bits (157), Expect = 5.8e-11
Identity = 41/63 (65.08%), Postives = 52/63 (82.54%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGPSSAASAALPSLGSLVGASLVSFVAY 155
           MEMK  AC  LFAAA+++A +AA+E  +P  APGP+SAASAALP+LGSLVGASLVS  +Y
Sbjct: 1   MEMKKIACGVLFAAASMTAVMAAEEVGAP--APGPASAASAALPALGSLVGASLVSLFSY 60

Query: 156 FLN 159
           +L+
Sbjct: 61  YLH 61

BLAST of Cla97C09G166550 vs. TAIR 10
Match: AT2G41905.1 (BEST Arabidopsis thaliana protein match is: arabinogalactan protein 23 (TAIR:AT3G57690.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). )

HSP 1 Score: 54.7 bits (130), Expect = 7.9e-08
Identity = 38/64 (59.38%), Postives = 48/64 (75.00%), Query Frame = 0

Query: 96  MEMKNFACAALFAAATLSAAVAADESLSPAAAPGP-SSAASAALPSLGSLVGASLVSFVA 155
           MEMK  AC  +FAAA+++A +AA+     A APGP +S AS A+P+LGSLVGASLVS  A
Sbjct: 1   MEMKKIACGVVFAAASMTAVMAAEVG---APAPGPAASGASVAVPALGSLVGASLVSLFA 60

Query: 156 YFLN 159
           Y+LN
Sbjct: 61  YYLN 61

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_038899473.12.2e-1588.89arabinogalactan protein 23-like [Benincasa hispida][more]
XP_023528634.11.1e-1485.71arabinogalactan peptide 23 [Cucurbita pepo subsp. pepo][more]
XP_023004714.11.1e-1485.71arabinogalactan peptide 23-like [Cucurbita maxima][more]
XP_022960230.11.4e-1485.71arabinogalactan peptide 23-like [Cucurbita moschata][more]
KAG7025661.13.1e-1484.13Arabinogalactan peptide 23, partial [Cucurbita argyrosperma subsp. argyrosperma][more]
Match NameE-valueIdentityDescription
Q8S2W48.2e-1065.08Arabinogalactan protein 23 OS=Arabidopsis thaliana OX=3702 GN=AGP23 PE=1 SV=2[more]
Match NameE-valueIdentityDescription
A0A6J1KX425.2e-1585.71arabinogalactan peptide 23-like OS=Cucurbita maxima OX=3661 GN=LOC111497929 PE=4... [more]
A0A6J1H8I16.8e-1585.71arabinogalactan peptide 23-like OS=Cucurbita moschata OX=3662 GN=LOC111461032 PE... [more]
A0A6J1F3F57.5e-1482.54arabinogalactan peptide 23-like OS=Cucurbita moschata OX=3662 GN=LOC111439670 PE... [more]
A0A6J1IYE92.8e-1380.95arabinogalactan peptide 23-like OS=Cucurbita maxima OX=3661 GN=LOC111479619 PE=4... [more]
A0A1S3CDX51.7e-1079.69arabinogalactan peptide 23-like OS=Cucumis melo OX=3656 GN=LOC103499912 PE=4 SV=... [more]
Match NameE-valueIdentityDescription
AT3G57690.15.8e-1165.08arabinogalactan protein 23 [more]
AT2G41905.17.9e-0859.38BEST Arabidopsis thaliana protein match is: arabinogalactan protein 23 (TAIR:AT3... [more]
InterPro
Analysis Name: InterPro Annotations of Watermelon (97103) v2.5
Date Performed: 2022-01-31
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePANTHERPTHR34672:SF2ARABINOGALACTAN PROTEIN 23coord: 78..157
IPR044702Arabinogalactan protein 23/40PANTHERPTHR34672POLLEN-SPECIFIC ARABINOGALACTA PROTEIN BAN102coord: 78..157

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Cla97C09G166550.2Cla97C09G166550.2mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane