ClCG11G012615 (gene) Watermelon (Charleston Gray) v2.5

Overview
NameClCG11G012615
Typegene
OrganismCitrullus lanatus subsp. vulgaris cv. Charleston Gray (Watermelon (Charleston Gray) v2.5)
DescriptionCCHC-type domain-containing protein
LocationCG_Chr11: 25822609 .. 25827070 (-)
RNA-Seq ExpressionClCG11G012615
SyntenyClCG11G012615
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGTCCGATTGGTTTGGTTGGGTATCGGCAGCAGTCAACAACAACTTGAAGGATTTTATAGAGAAAACGCCAACAGCTGTTCAGATTCCACCCGATGGTGCCTGGTTCATCGGCTGTGGGGGCGGGCATGTTGAGGAAATTGAGGACCAAGCCTGTGCCTCTCTATCTAAAAGAGGTCTCCTGAAAGCAGGATTCCACCTTCTTTGATTAGCGTCCCAAGCGTCTTTGACGGATATGAGTTTGTTGTCAGAGAGATTGTAGAATCTGTGATGCTCGGTCCTTTTAGGAGAATCGCTATCCTAAAGATGAAACCAGAATAAGGTGTTCAACCCGCTATTAATATTCCACTTGGTTTGGTTAGTGATGGTGTGAGCCATTTTTGAGATATGGAACCAAGGCGCTTTTGCACTGCCAAAGATAGTTTTGCTAGGAGCAGAACCAGGAGAGCATAGGTGTATTTAGCATCAATGAGTTCGAGAAGTATCTCCAAATCCATTTCCCCAAAACTGCATCGTTTGTGGCTCTGATTTTGTCTATCCCAACTTCCTACTTATAGATATCATATATTTATATTATATAAACATCGATCCTATCTAGGTCTTTACTTCATAATTCAATTTCAATTCAAGGAAATATGTGAAATGACATAATTGAAAGTTCCACTAACTTTGTTTTCAACATTATAATATGAAGTAATAATTCAAGTTGAAAAATGATCAAAGTGCTCAAATTCATATGAAGACTCTTGCTTTTATCATGAAATTTCTAAAAGAATTAGCAATAATTCTCATTTTCAACTCGCTTCAAAAGAAAAAGAAAATCTCGTTTTCAACTTTGGGAAGTTAACGTAAGTACATAAAACACCAAAATGAGAAAATAAAATATATCAAAAAATGTCTAGCTTAAATTTAGTCTTAAATTTAATAAATTCAAAGTTATGAAATTAGTTGAATAAAAATTTTCATGCAAGAAAAAAAAACACTATGGAAATATATTTTCACCATTTGTAAAGAGAATGCTAATAGATTACTTCTTTCTTTTTTTTTTTTTTTTTTTGGAAAGAAATCAACATAAACTAACTCAAGAGACCAATTTTAAGATTTAAGTATATATAGACTAAAATAAAATGTATAGAAATTGAAATGAAACGAAACTCATCCTTGAGAGACTTTAGGGTTGAACCTCCATTAGAGAAAAAAAATGATTTAGAGCAAAAAAATAATTCTCAAATACAGAAGCAAATTTAGTATTTCAATAATAAATGGTAGCGAGTAAATTTTTGGATGTTTCTCAATCAATCACTCCACCAAAAATCATATCTCAACTAATTATTAAAAAATAATTTTAACAATGACAAAACTATTTTTAACCATGCTAAATCTACTCTCAAACATACCCTTATTATAGTAGGATTTTGAGAAAGACATTATCCATTTGTTAACAATTTAGTATATTAACGAAAAGTATAATTATTTTTTTTCAAATTTAAAGACCAAAATAGATACTTTTAAATTTTTAATTAAGAACCAAAACGAAATAAGACTTAAAAGTGTAAGGAGAAAAATAATTTTAATATTTTAGGGACCAAAATTTAGTAATCCTAATAGTTTATAGATTAAAATAAAGATTTAAACATGTTTTCAACTTTTGATCTTAGAATAATTAACTATATTCACTTTAATATATAAAAAAAAAAGCATTACTTTCTATTTATAGATATTATATATGCAATGTTAATATACTATAAACATCGATCCAATTCTATTTCTTTACTTCAAAATTCATTTTGAATTCAATGAATCCGAAATTACATAATTGAAAGTTTCACTTTCATTTTTAACATAGTAATAATTCATGAAGTTGAGAATTGGTCATCTAAGATTTTAAATTCATAGAGCCTCTTGCTTTTATCATGGAATTTTTAAAAGAATTAGCAATATTGTTTATCTTTAGCCAAAATAAGCATTGCTCAACTGACATATGAGTATACTGATGACGAAAAAGTTTGTGGTTCAAATCCCCACATGTCTAATTGTACTAAAATAAATTTCTAAAATAAATTCCTATCTTCAACTTTAGGAAAATTAACGGAAGGCGCATAAACACCATAAAAAGAAAAAAATATTTATCAAATTTAAAATATCATTTTTATCTATATATTTTAATTTCTATTTGATTTTTGTCTTTATAATAGCTTCATATATACACTATGTGAGATTTTTTTCTGAAAAAAATTTAATAATAAACTATTTTCAATGATCAATATATATACTAAAATTAAATAATTAAAAAATAAAGGTACTAAAATGAAACAAAACTTAAAGTGTAGAGAGAGAAAATATTTTGATCCATAGTTTAAAAATAATGAGTTAAAACGTGAAAAAACTTAAAGTGTAGAGTGAGAAAATATTTGGATCCATAGGTTAAAAATAATGAGTTAAAACGTGAGAAAGAAATAATATGATATTATTGGTTAGGGCCACAGCCAAAATTAATTATTTTATATACGAACAAAGGAACAAATAGGTAATAACATGTGACTTTAATTGAGGTTTGGTCTAATTCTTATGAAATGATTGTTGGTCTTTGAACATTCCCCACACATTTACATCAAGAGGAAAAAATCAATTTACACCTCTAAACTATAAATTTTGGAATTGTCTCAAAACTAATAATTATATCAGTTTAAAATTTAAACTTTTGAAAATGTATCAATTAACACCCTCATTCAGACTTAATTCAGAAAATATCATGTGAAATATATATAGTTGTTTCAATTAAACTTTTAAATTGTTATAAGTGAATCAATTTAGACTCTTTATTAAGATCACATTTGAAAATCGTCTATGCATTAAATTTTTAAACGTGTGTAGACTTCTTCAAATGTTAAATTAATAAAGTGGACCATTAGAATTGATGCATGGACAATTTTAAAAGGAAATCTTAATTGAGAGTTTAAATTGATTCATTAATGAAACTATACAGGTTCAATTGATAAAATTATAAGTCTCATATGATAATCATCCAAACATAATATAATGGAGGGTGTAAATTAATACACTTTTAGAAGCACGAAGTTGAAATTGATATGATAATTAATTAATTCAGATTTAAATAAATACAACTCCAAAAGTTTAAGAATATATATTTATATTTTTCTCTTAAAAGTTAAAAGCGATTTTCTAGATATGTTTTGATATTAATTAAGGAAATAAAGCAAAGTTAGATCATAAACGTATAAAATTTCACTCCAAAACTTTTAAATGTTACCATTTTGATTGTTTGATAAGTTATCGGGCCAAATATCCTTAAAATTTTTCTTGTACATACATATGATATGAAATGAATAAAATTTTCGATTGAGAGCAACTATAGAGATTTTTTCTTTTTTATGAATTTTGGAAAGTTAATTTGTGTATGGTTAAACTTATTTTTGTGATATTTTGGTGAAATTAGTGATTTAAAAAAAAATAGAATTTGTGAATTATTTGTGAAGATTTTGCACTTTTATTTTAATAAACTTAGTGGATGAAGTAGCGAAAGTTAAATTGAGCTTACAAATGGTAACTCTAATTTAAATTAGTGTCCAATTTGATGAAACTAAAAATTTGAGGTCCAAGCTAATACAAGCTAATTGATTTTTTGGGCCTAATAATATAATAAAAGATTTAGGAAATTAGCCTCTCTCAGGTGGAAATGTTGTCTCGAATGCTCTAGCAGGAGAGTTTCATGGAGAAGTTGGTTGGAGTTGTTGTGTGTGTACGACCATAATGGCTGGGGAATTGGTAGTAGATTGGCATAAACTTTCCTTGACAAGGGATGAGGATAATGTAGCGATGGAGGTCGGAAAGGAGATGATGGTTTGTTTGGTCCTCGTCTTATCTTTGGGGACGTGATTTTCAAAGCATTATCTATGGTTTGGAAAGTGGAACAAAGGTTGGGTGTCGATAACATTGGTAAGGATCTATTCCTTTTCAACTTCTCCAATATCACTGACTGGTATAGGGTTTATCAGACGGGGCCCTGGATTTTGATAAATATTTGTTAGTGTTGGAATTACCAAAGCCTCTAATTAATCCAAATGAGTTATCCTTCAAACTAGTTGCCTTTTGGGTTCATTTTTTTCGAACTTTGATGGTTTGTATGACCTAATCTATGGCAAGGAAATTGGGTAATGCAATGGGTGAGTTTGAGCGTGTTGGGTATAACAGAAATGAGTTTTTGTTAGGGATCAAGCTTGCAGGTTTGGATCCCACTGGACATCACCAAGCCATTGAGGCATGGTATCAAGTTGAATATTTTGGATGGGGCGATTGACGGACGTTGGGTTCCAATGAAGTATGAGCGGCTGCTTGAGTTTTGCTCTTATTGTGGTTTGGTGGGGCACGAGGTAAAAGGTTGCAAATTAAACCTTAGCTATCCATTACACCTAATATGCGAGAACATAATCATGCATCGTTAA

mRNA sequence

ATGTCCGATTGGTTTGGTTGGGTATCGGCAGCAGTCAACAACAACTTGAAGGATTTTATAGAGAAAACGCCAACAGCTGTTCAGATTCCACCCGATGGTGCCTGGTTCATCGGCTGTGGGGGCGGGCATGTTGAGGAAATTGAGGACCAAGCCTGTGCCTCTCTATCTAAAAGAGGAGAGTTTCATGGAGAAGTTGGTTGGAGTTGTTGTGTGTGTACGACCATAATGGCTGGGGAATTGGTAGTAGATTGGCATAAACTTTCCTTGACAAGGGATGAGGATAATGTAGCGATGGAGGTCGGAAAGGAGATGATGGGATCAAGCTTGCAGGTTTGGATCCCACTGGACATCACCAAGCCATTGAGGCATGGTATCAAGTTGAATATTTTGGATGGGGCGATTGACGGACGTTGGGTTCCAATGAAGTATGAGCGGCTGCTTGAGTTTTGCTCTTATTGTGGTTTGGTGGGGCACGAGGTAAAAGGTTGCAAATTAAACCTTAGCTATCCATTACACCTAATATGCGAGAACATAATCATGCATCGTTAA

Coding sequence (CDS)

ATGTCCGATTGGTTTGGTTGGGTATCGGCAGCAGTCAACAACAACTTGAAGGATTTTATAGAGAAAACGCCAACAGCTGTTCAGATTCCACCCGATGGTGCCTGGTTCATCGGCTGTGGGGGCGGGCATGTTGAGGAAATTGAGGACCAAGCCTGTGCCTCTCTATCTAAAAGAGGAGAGTTTCATGGAGAAGTTGGTTGGAGTTGTTGTGTGTGTACGACCATAATGGCTGGGGAATTGGTAGTAGATTGGCATAAACTTTCCTTGACAAGGGATGAGGATAATGTAGCGATGGAGGTCGGAAAGGAGATGATGGGATCAAGCTTGCAGGTTTGGATCCCACTGGACATCACCAAGCCATTGAGGCATGGTATCAAGTTGAATATTTTGGATGGGGCGATTGACGGACGTTGGGTTCCAATGAAGTATGAGCGGCTGCTTGAGTTTTGCTCTTATTGTGGTTTGGTGGGGCACGAGGTAAAAGGTTGCAAATTAAACCTTAGCTATCCATTACACCTAATATGCGAGAACATAATCATGCATCGTTAA

Protein sequence

MSDWFGWVSAAVNNNLKDFIEKTPTAVQIPPDGAWFIGCGGGHVEEIEDQACASLSKRGEFHGEVGWSCCVCTTIMAGELVVDWHKLSLTRDEDNVAMEVGKEMMGSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGLVGHEVKGCKLNLSYPLHLICENIIMHR
Homology
BLAST of ClCG11G012615 vs. NCBI nr
Match: XP_022156185.1 (uncharacterized protein LOC111023135 [Momordica charantia] >XP_022156186.1 uncharacterized protein LOC111023135 [Momordica charantia])

HSP 1 Score: 78.2 bits (191), Expect = 8.3e-11
Identity = 31/58 (53.45%), Postives = 45/58 (77.59%), Query Frame = 0

Query: 106 GSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGLVGHEVKGC 164
           G+SL++ + +DITKPLR GIK+NI DG + G W+P++YERL +FC +CG++GH    C
Sbjct: 168 GASLRIRVLIDITKPLRRGIKINI-DGPMGGCWIPIQYERLPDFCYFCGVIGHSSHDC 224

BLAST of ClCG11G012615 vs. NCBI nr
Match: XP_022158377.1 (uncharacterized protein LOC111024874 [Momordica charantia])

HSP 1 Score: 72.4 bits (176), Expect = 4.5e-09
Identity = 32/50 (64.00%), Postives = 41/50 (82.00%), Query Frame = 0

Query: 106 GSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGL 156
           GS+L+V + LDI+KPLR GIKLN LDG I G W+P++YERL +FC +CGL
Sbjct: 169 GSNLRVRVMLDISKPLRRGIKLN-LDGPIGGAWIPIQYERLPDFCYHCGL 217

BLAST of ClCG11G012615 vs. NCBI nr
Match: KAE8782072.1 (hypothetical protein D1007_44590 [Hordeum vulgare])

HSP 1 Score: 70.5 bits (171), Expect = 1.7e-08
Identity = 34/75 (45.33%), Postives = 48/75 (64.00%), Query Frame = 0

Query: 96  VAMEVGKEMM--GSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYC 155
           V +EVG++ M  G SL++ + LDITKPL  G  ++  D     RW P +YE L EFC  C
Sbjct: 122 VDVEVGEDGMAEGESLRIKVKLDITKPLMRGTVIHTGDDE-RVRWCPFRYEYLREFCYIC 181

Query: 156 GLVGHEVKGCKLNLS 169
           G++GHE K C ++L+
Sbjct: 182 GIIGHEEKNCSVSLT 195

BLAST of ClCG11G012615 vs. NCBI nr
Match: TVU42476.1 (hypothetical protein EJB05_08883, partial [Eragrostis curvula])

HSP 1 Score: 69.3 bits (168), Expect = 3.8e-08
Identity = 43/133 (32.33%), Postives = 63/133 (47.37%), Query Frame = 0

Query: 32  DGAWFIGCGGGHVEEIEDQACASLSKRGEFHGEVGWSCCVCTTIMAGELVVDWHKLSLTR 91
           DG WF+G     +  +E      L +  EFH    W     T I  G  ++D        
Sbjct: 104 DGPWFVGHSHDLIVVVEYDE-GKLVEEVEFHHIPIW--IRVTKIPMG--LMDRDTGVAIG 163

Query: 92  DEDNVAMEVGKEMMGSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCS 151
           D+    +EV +   G  L++ + LDI  P+  G+ L + D    GRW P++YE L EFC 
Sbjct: 164 DKIGQCLEVDEASNGPFLRIKVQLDIRVPILRGVMLEV-DEKRHGRWCPLEYEFLPEFCH 223

Query: 152 YCGLVGHEVKGCK 165
            CG++GH  K C+
Sbjct: 224 LCGIIGHIDKNCQ 230

BLAST of ClCG11G012615 vs. NCBI nr
Match: DAD26304.1 (TPA_asm: hypothetical protein HUJ06_027772 [Nelumbo nucifera])

HSP 1 Score: 68.9 bits (167), Expect = 5.0e-08
Identity = 38/87 (43.68%), Postives = 48/87 (55.17%), Query Frame = 0

Query: 93  EDNVAMEVGKEMMGSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSY 152
           EDN  +E GK M GS ++  I +D+ KPL  G  L   +  I   WV   YE L + C Y
Sbjct: 121 EDNPEIEPGKPMRGSMVRFHIEIDLRKPLSRGFFLKNNNNPI---WVRFAYENLTKLCIY 180

Query: 153 CGLVGHEVKGCKL-NLSYPLHLICENI 179
           CGLVGH+ K CKL   S PL+ I   +
Sbjct: 181 CGLVGHKWKKCKLIPKSIPLNEIMSEL 204

BLAST of ClCG11G012615 vs. ExPASy TrEMBL
Match: A0A6J1DU55 (uncharacterized protein LOC111023135 OS=Momordica charantia OX=3673 GN=LOC111023135 PE=4 SV=1)

HSP 1 Score: 78.2 bits (191), Expect = 4.0e-11
Identity = 31/58 (53.45%), Postives = 45/58 (77.59%), Query Frame = 0

Query: 106 GSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGLVGHEVKGC 164
           G+SL++ + +DITKPLR GIK+NI DG + G W+P++YERL +FC +CG++GH    C
Sbjct: 168 GASLRIRVLIDITKPLRRGIKINI-DGPMGGCWIPIQYERLPDFCYFCGVIGHSSHDC 224

BLAST of ClCG11G012615 vs. ExPASy TrEMBL
Match: A0A6J1DX30 (uncharacterized protein LOC111024874 OS=Momordica charantia OX=3673 GN=LOC111024874 PE=4 SV=1)

HSP 1 Score: 72.4 bits (176), Expect = 2.2e-09
Identity = 32/50 (64.00%), Postives = 41/50 (82.00%), Query Frame = 0

Query: 106 GSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGL 156
           GS+L+V + LDI+KPLR GIKLN LDG I G W+P++YERL +FC +CGL
Sbjct: 169 GSNLRVRVMLDISKPLRRGIKLN-LDGPIGGAWIPIQYERLPDFCYHCGL 217

BLAST of ClCG11G012615 vs. ExPASy TrEMBL
Match: A0A803LW54 (Uncharacterized protein OS=Chenopodium quinoa OX=63459 PE=4 SV=1)

HSP 1 Score: 69.3 bits (168), Expect = 1.9e-08
Identity = 40/103 (38.83%), Postives = 58/103 (56.31%), Query Frame = 0

Query: 76  MAGELVVDWHKLSLTRDEDNVAM-----EVG-------KEMMGSS--LQVWIPLDITKPL 135
           M  EL+ DW KL LT DE+ V +     E+G        + +G +  L++ + +D+ KPL
Sbjct: 1   MGDELMKDWEKLRLT-DEEGVVLGGDYVEIGGFVEADESDPLGCNDCLRIKVLVDVNKPL 60

Query: 136 RHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGLVGHEVKGCK 165
           R G+ L +  G    RWV +KYERL EFC +CG + H  K C+
Sbjct: 61  RRGLFLAM--GQNKPRWVDVKYERLAEFCFFCGRLDHTEKECQ 100

BLAST of ClCG11G012615 vs. ExPASy TrEMBL
Match: A0A5J9W3H8 (Uncharacterized protein (Fragment) OS=Eragrostis curvula OX=38414 GN=EJB05_08883 PE=4 SV=1)

HSP 1 Score: 69.3 bits (168), Expect = 1.9e-08
Identity = 43/133 (32.33%), Postives = 63/133 (47.37%), Query Frame = 0

Query: 32  DGAWFIGCGGGHVEEIEDQACASLSKRGEFHGEVGWSCCVCTTIMAGELVVDWHKLSLTR 91
           DG WF+G     +  +E      L +  EFH    W     T I  G  ++D        
Sbjct: 104 DGPWFVGHSHDLIVVVEYDE-GKLVEEVEFHHIPIW--IRVTKIPMG--LMDRDTGVAIG 163

Query: 92  DEDNVAMEVGKEMMGSSLQVWIPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCS 151
           D+    +EV +   G  L++ + LDI  P+  G+ L + D    GRW P++YE L EFC 
Sbjct: 164 DKIGQCLEVDEASNGPFLRIKVQLDIRVPILRGVMLEV-DEKRHGRWCPLEYEFLPEFCH 223

Query: 152 YCGLVGHEVKGCK 165
            CG++GH  K C+
Sbjct: 224 LCGIIGHIDKNCQ 230

BLAST of ClCG11G012615 vs. ExPASy TrEMBL
Match: A0A803N142 (Uncharacterized protein OS=Chenopodium quinoa OX=63459 PE=4 SV=1)

HSP 1 Score: 67.0 bits (162), Expect = 9.2e-08
Identity = 41/116 (35.34%), Postives = 58/116 (50.00%), Query Frame = 0

Query: 76  MAGELVVDWHKLSLTRDEDNV----AMEVGKEMMGSSLQV-----------------W-- 135
           MA +LV DW KL LT DE  V    ++E  KE  GS++Q+                 W  
Sbjct: 1   MANDLVKDWEKLKLTEDEVAVIGGESLETDKE--GSNIQLKLTLVGFNELDDEDTLGWSD 60

Query: 136 -----IPLDITKPLRHGIKLNILDGAIDGRWVPMKYERLLEFCSYCGLVGHEVKGC 164
                I +DI KPLR   KL+   G+   +W+ +K ERL +FC +CG++ H  + C
Sbjct: 61  IVRLKINVDIRKPLRRRFKLS--TGSASSKWINIKNERLADFCFFCGMLDHTDRDC 112

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_022156185.18.3e-1153.45uncharacterized protein LOC111023135 [Momordica charantia] >XP_022156186.1 uncha... [more]
XP_022158377.14.5e-0964.00uncharacterized protein LOC111024874 [Momordica charantia][more]
KAE8782072.11.7e-0845.33hypothetical protein D1007_44590 [Hordeum vulgare][more]
TVU42476.13.8e-0832.33hypothetical protein EJB05_08883, partial [Eragrostis curvula][more]
DAD26304.15.0e-0843.68TPA_asm: hypothetical protein HUJ06_027772 [Nelumbo nucifera][more]
Match NameE-valueIdentityDescription
Match NameE-valueIdentityDescription
A0A6J1DU554.0e-1153.45uncharacterized protein LOC111023135 OS=Momordica charantia OX=3673 GN=LOC111023... [more]
A0A6J1DX302.2e-0964.00uncharacterized protein LOC111024874 OS=Momordica charantia OX=3673 GN=LOC111024... [more]
A0A803LW541.9e-0838.83Uncharacterized protein OS=Chenopodium quinoa OX=63459 PE=4 SV=1[more]
A0A5J9W3H81.9e-0832.33Uncharacterized protein (Fragment) OS=Eragrostis curvula OX=38414 GN=EJB05_08883... [more]
A0A803N1429.2e-0835.34Uncharacterized protein OS=Chenopodium quinoa OX=63459 PE=4 SV=1[more]
Match NameE-valueIdentityDescription
InterPro
Analysis Name: InterPro Annotations of Watermelon (Charleston Gray) v2.5
Date Performed: 2022-01-31
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR025836Zinc knuckle CX2CX4HX4CPFAMPF14392zf-CCHC_4coord: 115..164
e-value: 2.2E-13
score: 49.7

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
ClCG11G012615.1ClCG11G012615.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
molecular_function GO:0003676 nucleic acid binding
molecular_function GO:0004523 RNA-DNA hybrid ribonuclease activity