Chy1G014470 (gene) Cucumber (hystrix) v1

Overview
NameChy1G014470
Typegene
OrganismCucumis hystrix (Cucumber (hystrix) v1)
DescriptionDUF4218 domain-containing protein
LocationchrH01: 20120671 .. 20121815 (+)
RNA-Seq ExpressionChy1G014470
SyntenyChy1G014470
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDSpolypeptide
Hold the cursor over a type above to highlight its positions in the sequence below.
GTTGATAACATTGTTGCAGCAAGAACGGTTTTCGAAAGAATAAGTACGGATGAGATACTTTATGGAGTACGACTTGGAGCAGGTGATGTGCGATTTCTCGTTGAACTTGCACGTGACAATCATTCTCTACTGCACATACCGATTGTTGGAAGCATCTATTCTGTACACGATGCAATTGGTTCAAACGTTCCATGGAAAAAGCATCTTATAGTTATAGAAAAACAAAAAAAGGTAAAGTTTTAATATCAAAATATAAATTTTTGCACATAAGCATGTATTCATTTTAATTTTTGACATTCTTTTTATATAGACATCTAGTAAAAAGTCTTGTGAGGCAAAATCTTTGAAAGGAACAAAATAAAAAATTAATGAATTAAAATTGTCAATAACAATAAGGTTCGTGTTGAGGCATGTAGAGAAGGATATGAAAGATGAATATCTTACTATCCCAGTCGACACTGAGGAGATTTTTGGGTATAGCTTCAATGTGAACGTGATGAATGACAGCATTAAACAATTTTTTCTGATGTAAGTGCGCAAGTTTAAAATCTTATTTTTATTATATTTTTAGATGCTTATTTCTATTATTACAAGTTTTTTTTTTAATGTCAGATGCTTATATGAATCTGATCCAAGTATTCTAGATGAATATGCATTCATGAATCCTGTACAAATTTCAAAAGGTTCAGGTACTGACGAACATAAAGCTCGATATTTGTGTAATAGATTGATATCGATCAAGAATAAATTATTGATATGTCTATTTAATTGCAGGTAAGTTAGAAAACAAGTATTGTTATTTTTCATATGTTTTTTAATTATAATATTTTTTATTAACTTGATTGAAACATATGTTTATTATATAGATATCATTAGATATTATTTATTATCTCATTATGGACGAATACGGTGTATGCACTTGATTTGTTAAGACATGGTAGTGTTCGAGACGAGTTGAAATCTATGGTGAACACGTAAGTATTTGACAGTTATTTCACATAAGTGTATATTTATTGTATAAATTGTAGTTTGTTATATCTTTTATATTTTTTTATTCTTTTTAATCCAGAGCCTTAAGAATGTTTTATGCTGAAACAAATACAAGAGCTCGACCTTTTACTTGGGTTTCAAGTATGAGTACTTAA

mRNA sequence

GTTGATAACATTGTTGCAGCAAGAACGGTTTTCGAAAGAATAAGTACGGATGAGATACTTTATGGAGTACGACTTGGAGCAGGTGATGTGCGATTTCTCGTTGAACTTGCACGTGACAATCATTCTCTACTGCACATACCGATTGTTGGAAGCATCTATTCTGTACACGATGCAATTGGTTCAAACGTTCCATGGAAAAAGCATCTTATAGTTATAGAAAAACAAAAAAAGACATCTAGTAAAAAGTTCGTGTTGAGGCATGTAGAGAAGGATATGAAAGATGAATATCTTACTATCCCAGTCGACACTGAGGAGATTTTTGGGTATAGCTTCAATGTGAACGTGATGAATGACAGCATTAAACAATTTTTTCTGATATGCTTATATGAATCTGATCCAAGTATTCTAGATGAATATGCATTCATGAATCCTGTACAAATTTCAAAAGGTTCAGGTAAGTTAGAAAACAAGTATTGTTATTTTTCATATATATTATTTATTATCTCATTATGGACGAATACGGTGTATGCACTTGATTTGTTAAGACATGGTAGTGTTCGAGACGAGTTGAAATCTATGGTGAACACAGCCTTAAGAATGTTTTATGCTGAAACAAATACAAGAGCTCGACCTTTTACTTGGGTTTCAAGTATGAGTACTTAA

Coding sequence (CDS)

GTTGATAACATTGTTGCAGCAAGAACGGTTTTCGAAAGAATAAGTACGGATGAGATACTTTATGGAGTACGACTTGGAGCAGGTGATGTGCGATTTCTCGTTGAACTTGCACGTGACAATCATTCTCTACTGCACATACCGATTGTTGGAAGCATCTATTCTGTACACGATGCAATTGGTTCAAACGTTCCATGGAAAAAGCATCTTATAGTTATAGAAAAACAAAAAAAGACATCTAGTAAAAAGTTCGTGTTGAGGCATGTAGAGAAGGATATGAAAGATGAATATCTTACTATCCCAGTCGACACTGAGGAGATTTTTGGGTATAGCTTCAATGTGAACGTGATGAATGACAGCATTAAACAATTTTTTCTGATATGCTTATATGAATCTGATCCAAGTATTCTAGATGAATATGCATTCATGAATCCTGTACAAATTTCAAAAGGTTCAGGTAAGTTAGAAAACAAGTATTGTTATTTTTCATATATATTATTTATTATCTCATTATGGACGAATACGGTGTATGCACTTGATTTGTTAAGACATGGTAGTGTTCGAGACGAGTTGAAATCTATGGTGAACACAGCCTTAAGAATGTTTTATGCTGAAACAAATACAAGAGCTCGACCTTTTACTTGGGTTTCAAGTATGAGTACTTAA

Protein sequence

VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIGSNVPWKKHLIVIEKQKKTSSKKFVLRHVEKDMKDEYLTIPVDTEEIFGYSFNVNVMNDSIKQFFLICLYESDPSILDEYAFMNPVQISKGSGKLENKYCYFSYILFIISLWTNTVYALDLLRHGSVRDELKSMVNTALRMFYAETNTRARPFTWVSSMST*
Homology
BLAST of Chy1G014470 vs. ExPASy TrEMBL
Match: A0A5A7VPW2 (DUF4218 domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold352G00380 PE=4 SV=1)

HSP 1 Score: 253.4 bits (646), Expect = 8.4e-64
Identity = 141/230 (61.30%), Postives = 155/230 (67.39%), Query Frame = 0

Query: 24  RLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIGSNVPWKKHLIVIEKQKKTSSKK- 83
           RLG GDVR L+ELA D+HSLL IP+VGSIYSVHDAIGS+VPW+K+LI IE+QKKTSSKK 
Sbjct: 473 RLGEGDVRVLIELACDSHSLLPIPVVGSIYSVHDAIGSHVPWRKYLIAIEEQKKTSSKKC 532

Query: 84  -----------------------FVLRHVEKDMKDEYLTIPVDTEEIFGYSFNVNVMNDS 143
                                  FVL+HVEKDMKDEYLTIPVDT+E+ GYSFNVNVM DS
Sbjct: 533 RELEALKGTKSKMNELKLPLTIRFVLKHVEKDMKDEYLTIPVDTQELLGYSFNVNVMKDS 592

Query: 144 IKQF-------------FLICLYESDPSILDEYAFMNPVQISKGSGKLENKYCYFSYILF 203
           IKQ              ++ICLYESDPSI++EYAFMNP QI K                 
Sbjct: 593 IKQLCLMEELTLSVILSYMICLYESDPSIVEEYAFMNPGQILK----------------- 652

Query: 204 IISLWTNTVYALDLLRHGSVRDELKSMVNTALRMFYAETNTRARPFTWVS 217
                   VYALD LRHGSVRDELKSMVNT LRMFYAETNTRARP TWVS
Sbjct: 653 --------VYALDSLRHGSVRDELKSMVNTGLRMFYAETNTRARPLTWVS 677

BLAST of Chy1G014470 vs. ExPASy TrEMBL
Match: A0A5A7UBK9 (Putative transposase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold102G00720 PE=4 SV=1)

HSP 1 Score: 220.7 bits (561), Expect = 6.1e-54
Identity = 121/184 (65.76%), Postives = 134/184 (72.83%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA  TVFERIST EI+YGVRLG GDV  L+ELA D+HSLL IPIV SIYS+HDAIG
Sbjct: 355 VDNIVATGTVFERISTGEIVYGVRLGEGDVGVLIELACDSHSLLPIPIVESIYSIHDAIG 414

Query: 61  SNVPWKKHLIVIEKQKKTSSKK------------------------FVLRHVEKDMKDEY 120
           S+VPW K+LIVIE+QKKTSSKK                        FVLRHVEKDM+DEY
Sbjct: 415 SHVPWPKYLIVIEEQKKTSSKKSHELEALKGTKSKMNELKLPTTIRFVLRHVEKDMEDEY 474

Query: 121 LTIPVDTEEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMN 148
           LTIPVDT+EIFGYSFNVNVM DS+KQ              ++ICLYESDPSIL+EYAFMN
Sbjct: 475 LTIPVDTQEIFGYSFNVNVMKDSMKQLCLMEELAFSVILSYMICLYESDPSILEEYAFMN 534

BLAST of Chy1G014470 vs. ExPASy TrEMBL
Match: A0A5D3D5S7 (Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold204G00800 PE=4 SV=1)

HSP 1 Score: 220.3 bits (560), Expect = 7.9e-54
Identity = 122/194 (62.89%), Postives = 137/194 (70.62%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA   VFERIST+EI+Y VRLG GDV   +ELA D+HSLL IPIVG+IYSVHDAIG
Sbjct: 117 VDNIVAIGIVFERISTNEIVYRVRLGEGDVWVFIELACDSHSLLPIPIVGNIYSVHDAIG 176

Query: 61  SNVPWKKHLIVIEKQKKTSSKK------------------------FVLRHVEKDMKDEY 120
           S+V W+K+LIVIE+QKKTSSKK                        FVLRHVEKDM DEY
Sbjct: 177 SHVSWQKYLIVIEEQKKTSSKKPRELEALKGTKLKMNELKLSTTIRFVLRHVEKDMNDEY 236

Query: 121 LTIPVDTEEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMN 158
           LTIPVDT+EIFGYSFNVNVM DSIKQ              ++ICLYESDP IL+EY FMN
Sbjct: 237 LTIPVDTQEIFGYSFNVNVMKDSIKQLCLMEELALSVILSYIICLYESDPCILEEYEFMN 296

BLAST of Chy1G014470 vs. ExPASy TrEMBL
Match: A0A5D3BSF6 (Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold280G00180 PE=4 SV=1)

HSP 1 Score: 212.6 bits (540), Expect = 1.6e-51
Identity = 118/183 (64.48%), Postives = 132/183 (72.13%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA RTVFERISTDEI+YGVRLG G+V+ LVELA D+HSLL I IVGSI+S+HDAIG
Sbjct: 87  VDNIVATRTVFERISTDEIVYGVRLGEGNVQVLVELACDSHSLLPILIVGSIFSIHDAIG 146

Query: 61  SNVPWKKHLIVIEKQ-------KKTSSK----------KFVLRHVEKDMKDEYLTIPVDT 120
           S++PW K+LI   K+       K T SK          +FVLRHVEKD KDEYLTIPVDT
Sbjct: 147 SHIPWPKYLITSSKKSRESEALKGTKSKMNEFKLPTVIRFVLRHVEKDTKDEYLTIPVDT 206

Query: 121 EEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMNPVQISKG 154
            EIFGYSFNVNVM D IKQ              ++ICLYESDPSIL+EYAFMNP QI KG
Sbjct: 207 WEIFGYSFNVNVMKDGIKQLCLMEELALSMILSYIICLYESDPSILEEYAFMNPGQILKG 266

BLAST of Chy1G014470 vs. ExPASy TrEMBL
Match: A0A5A7TWM1 (Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold243G001620 PE=4 SV=1)

HSP 1 Score: 212.6 bits (540), Expect = 1.6e-51
Identity = 118/183 (64.48%), Postives = 132/183 (72.13%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA RTVFERISTDEI+YGVRLG G+V+ LVELA D+HSLL I IVGSI+S+HDAIG
Sbjct: 86  VDNIVATRTVFERISTDEIVYGVRLGEGNVQVLVELACDSHSLLPILIVGSIFSIHDAIG 145

Query: 61  SNVPWKKHLIVIEKQ-------KKTSSK----------KFVLRHVEKDMKDEYLTIPVDT 120
           S++PW K+LI   K+       K T SK          +FVLRHVEKD KDEYLTIPVDT
Sbjct: 146 SHIPWPKYLITSSKKSRESEALKGTKSKMNEFKLPTVIRFVLRHVEKDTKDEYLTIPVDT 205

Query: 121 EEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMNPVQISKG 154
            EIFGYSFNVNVM D IKQ              ++ICLYESDPSIL+EYAFMNP QI KG
Sbjct: 206 WEIFGYSFNVNVMKDGIKQLCLMEELALSMILSYIICLYESDPSILEEYAFMNPGQILKG 265

BLAST of Chy1G014470 vs. NCBI nr
Match: KAA0067725.1 (uncharacterized protein E6C27_scaffold352G00380 [Cucumis melo var. makuwa])

HSP 1 Score: 250 bits (639), Expect = 7.38e-75
Identity = 141/230 (61.30%), Postives = 155/230 (67.39%), Query Frame = 0

Query: 24  RLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIGSNVPWKKHLIVIEKQKKTSSKK- 83
           RLG GDVR L+ELA D+HSLL IP+VGSIYSVHDAIGS+VPW+K+LI IE+QKKTSSKK 
Sbjct: 473 RLGEGDVRVLIELACDSHSLLPIPVVGSIYSVHDAIGSHVPWRKYLIAIEEQKKTSSKKC 532

Query: 84  -----------------------FVLRHVEKDMKDEYLTIPVDTEEIFGYSFNVNVMNDS 143
                                  FVL+HVEKDMKDEYLTIPVDT+E+ GYSFNVNVM DS
Sbjct: 533 RELEALKGTKSKMNELKLPLTIRFVLKHVEKDMKDEYLTIPVDTQELLGYSFNVNVMKDS 592

Query: 144 IKQF-------------FLICLYESDPSILDEYAFMNPVQISKGSGKLENKYCYFSYILF 203
           IKQ              ++ICLYESDPSI++EYAFMNP QI K                 
Sbjct: 593 IKQLCLMEELTLSVILSYMICLYESDPSIVEEYAFMNPGQILK----------------- 652

Query: 204 IISLWTNTVYALDLLRHGSVRDELKSMVNTALRMFYAETNTRARPFTWVS 216
                   VYALD LRHGSVRDELKSMVNT LRMFYAETNTRARP TWVS
Sbjct: 653 --------VYALDSLRHGSVRDELKSMVNTGLRMFYAETNTRARPLTWVS 677

BLAST of Chy1G014470 vs. NCBI nr
Match: TYK18876.1 (uncharacterized protein E5676_scaffold204G00800 [Cucumis melo var. makuwa])

HSP 1 Score: 218 bits (555), Expect = 6.25e-66
Identity = 122/194 (62.89%), Postives = 137/194 (70.62%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA   VFERIST+EI+Y VRLG GDV   +ELA D+HSLL IPIVG+IYSVHDAIG
Sbjct: 117 VDNIVAIGIVFERISTNEIVYRVRLGEGDVWVFIELACDSHSLLPIPIVGNIYSVHDAIG 176

Query: 61  SNVPWKKHLIVIEKQKKTSSKK------------------------FVLRHVEKDMKDEY 120
           S+V W+K+LIVIE+QKKTSSKK                        FVLRHVEKDM DEY
Sbjct: 177 SHVSWQKYLIVIEEQKKTSSKKPRELEALKGTKLKMNELKLSTTIRFVLRHVEKDMNDEY 236

Query: 121 LTIPVDTEEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMN 157
           LTIPVDT+EIFGYSFNVNVM DSIKQ              ++ICLYESDP IL+EY FMN
Sbjct: 237 LTIPVDTQEIFGYSFNVNVMKDSIKQLCLMEELALSVILSYIICLYESDPCILEEYEFMN 296

BLAST of Chy1G014470 vs. NCBI nr
Match: KAA0053273.1 (putative transposase [Cucumis melo var. makuwa])

HSP 1 Score: 218 bits (556), Expect = 2.30e-64
Identity = 121/184 (65.76%), Postives = 134/184 (72.83%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA  TVFERIST EI+YGVRLG GDV  L+ELA D+HSLL IPIV SIYS+HDAIG
Sbjct: 355 VDNIVATGTVFERISTGEIVYGVRLGEGDVGVLIELACDSHSLLPIPIVESIYSIHDAIG 414

Query: 61  SNVPWKKHLIVIEKQKKTSSKK------------------------FVLRHVEKDMKDEY 120
           S+VPW K+LIVIE+QKKTSSKK                        FVLRHVEKDM+DEY
Sbjct: 415 SHVPWPKYLIVIEEQKKTSSKKSHELEALKGTKSKMNELKLPTTIRFVLRHVEKDMEDEY 474

Query: 121 LTIPVDTEEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMN 147
           LTIPVDT+EIFGYSFNVNVM DS+KQ              ++ICLYESDPSIL+EYAFMN
Sbjct: 475 LTIPVDTQEIFGYSFNVNVMKDSMKQLCLMEELAFSVILSYMICLYESDPSILEEYAFMN 534

BLAST of Chy1G014470 vs. NCBI nr
Match: KAA0045649.1 (uncharacterized protein E6C27_scaffold243G001620 [Cucumis melo var. makuwa])

HSP 1 Score: 210 bits (535), Expect = 2.21e-63
Identity = 118/183 (64.48%), Postives = 132/183 (72.13%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA RTVFERISTDEI+YGVRLG G+V+ LVELA D+HSLL I IVGSI+S+HDAIG
Sbjct: 86  VDNIVATRTVFERISTDEIVYGVRLGEGNVQVLVELACDSHSLLPILIVGSIFSIHDAIG 145

Query: 61  SNVPWKKHLIVIEKQ-------KKTSSK----------KFVLRHVEKDMKDEYLTIPVDT 120
           S++PW K+LI   K+       K T SK          +FVLRHVEKD KDEYLTIPVDT
Sbjct: 146 SHIPWPKYLITSSKKSRESEALKGTKSKMNEFKLPTVIRFVLRHVEKDTKDEYLTIPVDT 205

Query: 121 EEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMNPVQISKG 153
            EIFGYSFNVNVM D IKQ              ++ICLYESDPSIL+EYAFMNP QI KG
Sbjct: 206 WEIFGYSFNVNVMKDGIKQLCLMEELALSMILSYIICLYESDPSILEEYAFMNPGQILKG 265

BLAST of Chy1G014470 vs. NCBI nr
Match: TYK02613.1 (uncharacterized protein E5676_scaffold280G00180 [Cucumis melo var. makuwa])

HSP 1 Score: 210 bits (535), Expect = 2.27e-63
Identity = 118/183 (64.48%), Postives = 132/183 (72.13%), Query Frame = 0

Query: 1   VDNIVAARTVFERISTDEILYGVRLGAGDVRFLVELARDNHSLLHIPIVGSIYSVHDAIG 60
           VDNIVA RTVFERISTDEI+YGVRLG G+V+ LVELA D+HSLL I IVGSI+S+HDAIG
Sbjct: 87  VDNIVATRTVFERISTDEIVYGVRLGEGNVQVLVELACDSHSLLPILIVGSIFSIHDAIG 146

Query: 61  SNVPWKKHLIVIEKQ-------KKTSSK----------KFVLRHVEKDMKDEYLTIPVDT 120
           S++PW K+LI   K+       K T SK          +FVLRHVEKD KDEYLTIPVDT
Sbjct: 147 SHIPWPKYLITSSKKSRESEALKGTKSKMNEFKLPTVIRFVLRHVEKDTKDEYLTIPVDT 206

Query: 121 EEIFGYSFNVNVMNDSIKQF-------------FLICLYESDPSILDEYAFMNPVQISKG 153
            EIFGYSFNVNVM D IKQ              ++ICLYESDPSIL+EYAFMNP QI KG
Sbjct: 207 WEIFGYSFNVNVMKDGIKQLCLMEELALSMILSYIICLYESDPSILEEYAFMNPGQILKG 266

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
Match NameE-valueIdentityDescription
A0A5A7VPW28.4e-6461.30DUF4218 domain-containing protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C2... [more]
A0A5A7UBK96.1e-5465.76Putative transposase OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold102... [more]
A0A5D3D5S77.9e-5462.89Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold... [more]
A0A5D3BSF61.6e-5164.48Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold... [more]
A0A5A7TWM11.6e-5164.48Uncharacterized protein OS=Cucumis melo var. makuwa OX=1194695 GN=E6C27_scaffold... [more]
Match NameE-valueIdentityDescription
KAA0067725.17.38e-7561.30uncharacterized protein E6C27_scaffold352G00380 [Cucumis melo var. makuwa][more]
TYK18876.16.25e-6662.89uncharacterized protein E5676_scaffold204G00800 [Cucumis melo var. makuwa][more]
KAA0053273.12.30e-6465.76putative transposase [Cucumis melo var. makuwa][more]
KAA0045649.12.21e-6364.48uncharacterized protein E6C27_scaffold243G001620 [Cucumis melo var. makuwa][more]
TYK02613.12.27e-6364.48uncharacterized protein E5676_scaffold280G00180 [Cucumis melo var. makuwa][more]
Match NameE-valueIdentityDescription
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
Chy1G014470.1Chy1G014470.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0008234 cysteine-type peptidase activity