CcUC11G210630 (gene) Watermelon (PI 537277) v1

Overview
NameCcUC11G210630
Typegene
OrganismCitrullus colocynthis (Watermelon (PI 537277) v1)
Descriptionmethyltransferase-like protein 5
LocationCicolChr11: 2546410 .. 2550908 (-)
RNA-Seq ExpressionCcUC11G210630
SyntenyCcUC11G210630
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRpolypeptideCDSthree_prime_UTR
Hold the cursor over a type above to highlight its positions in the sequence below.
AAGAGACACGTCCTTTACACTATAGAAGATTGAGAAGAATCAGAGAGGACAAGTCGTGACTTGTTACAGGATATCCTCGCCTTTTTTTCAGAAAGATTAATCCCCTAAATTAGGGTTATCAAGAAAACGGATTCATCAAGATTCTCTCCACCCAACCATGAAGCTCAAGCAATTAGAGTCCTTAATAAGTGAAATTCAACAGTTCTCCAATCCAAAGGTTTGATTTCCTCGCCGGTTTTCCTTCGCTTCTTTACGCATTTGTTCAATCAACACAAACACACTCTGTAAAATTCGTTTCTCTTGCAGGTTGAGCTGGAGCAGTATCCCACTGGACCTCACATTGCTTCTCGCATGTTGTACACCGTACCTCTCTTCCCTCTTCTCCTTCATCTTTTCCTTTTGCTTTAATCTCTGTTTTTTTCCCATCTTATCCATGTTTGGGAGTGATTATGAAACAGTTTAAATCAATTTTGTCATGTTTAAAATCATCCAAAGTAAGTTTGAAAATAGAATAGGTGATTTTAAACATTTTACAATCATTCTCAAACATGCTATAAGTTGCCACCGGACCAATAGCTTAAATTGATGGACTATAGTAAATTTGATTATTTCAATGGTCTAATGCTCACTCTCACGTGTGGTTTGAGATTTATAGAAGACCCACCTAGTAGAAATCAAAATTAATTTGACATTACTACTTTGAACGTGTAACTTTCTGCTCTGATTTCGTATTACATTACCCTTGAACCCAAAAACAAGCCTAAAGGAACGGTTGATTTGACTATTCATAGTGCTGAGTTGTTTGGTTACTGGGTTAATTGGATTGAAAATCAAGTTGATTACTCAAGAAAGGATCATATGTTTTTGGTAAATAGTAATTTTTAAGTTTTATCATTACGTATGATAATTCATAATAACGATAGTAATGTTCAAATTTATACCTGTTTGCAGATTTTAGATGTCAGGAATTTTTTAGTTTTCTTCCTACTACGTATTTAACTCCTCTGTATTCCACTAGTTGAAAGCAGGGGCTAAAAGATCTACTACTTTAATTCGTGTTTCAAAAATTGACGAGGAGCTCCCTTCCATCGTTTTTTTTTAACCTACAGTTAATATTGGTTGTATCTTGGTGTAAATGCAGCCCCTCTTCCATTGCTACAGCTTTTTCTCCCTACTCTTCAATTGGAGAGGCTCTTGTAATATACCACACAGGGTTCTCCCCCATTTGTAATGAAATTGTTTCTTATCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATAATTTTGTATCTAATGGAATAAAGTAGGCGTAGATAAGGATTAATTTGTTATAAACAATAGATGTATTTCACATCCAACTATAGCAATGAATAATCAATAATAATTTTTTAATGGCAGTTCCAAAAAATTGATGAAACTAGAGCTTCCATCAACTGTTAGACCCTAAATTTCTACGTTTACTACATATTTGTTTAATTGTTTTATGTAATCATAGTTTATAACACGGGTCATTCATTTGAAACTTTATCAGGCAGAGAATTCTTTTGGAGATGTGAGTGGCAAGATAGTGGCTGATTTGGGTTGTGGTTGTGGTACATTAGGTGCTGCAGCTGCACTTTTGGGTGCAGAGTGAGTAGCATCTTCCCCCTGTTCCTCTCTATTTTCTTTTGGTTTATTACTCTTTTAATTTCGGTTGCGAATAGAGATTTTCAGTTCCATGGTTGAAAGTTATCAATCTTTTTCTGACTATAAGGGAAGCGGATAAAATGAATTTATTCAGCGTATATTGATTTTAAACATACCCAATGCTTCATGTCTTACAATTCTTGGACAGGCATGTTATCGGAATTGACATTGATCCTGAGTCTCTTGAAATAGCATCTTCAAATGCAGACTATCTTGAGGTTCTCTCTCTTGACTTTATGTATGACTATCATATGTTGGATTGGGATACTTCGGATCGTCTTCATTGCACACGTGTTCTCTTAGTTGATCTGTTGAAAATTGCAGTTGGAAATGGACTTGGTTCAGTGCGATGTGAAGAACTTAGGATGGAGAGGTAACAAAATGAAAAACCATGTTTGCTAACTTTCAATGCTTCTCATTCTCATCGTGCACCTGCATGCTTTTAAAATAGAATATGGGTTCTAGTTTTGAAAAAGTATGTTTAGATGAATGTATACTCTGTCCCAGTAATAATTCAACAATGTGGCTTTTTTCACTGAATTCATTGGATAACGAATGGGTGTGGGAGTGGAAGTTGGGTTGGCTTAGTTTGATAGAATTTGACGGTATTCTTATGTTATGCACAAGAAATCTATAATGTATAATGGCTGCTGGTTCCTCATGTGTCTTCTTCAATTCTCTTTTAATGAACTTTTTTTTTGAGCTAGTATACGTTTACCAAGGAAAAGTGGTTATTTTATAATAACGATAAATGATTTCACAAGGAAGAGGTCTACTGTTAATTGTTTGATTCACTTCATGATCTTATTGTTGGATCAATGATCATAACCGTTTTAGTAATTGGTTAGTATTATTTGTGTCAAAGGTTTAATGAATTTATGATACTGCACGAGTCGTTAGCATCTATAGATGTTTGTCTTTAGATGGATGGTGATAAAATGAAAGTGTTCAGATTCAGTTTTCAACTTTTCATCATAACACAGTTTCCCTAGGCATATTTTCTTTGATCCAAGTACCTTTTGTCAAGACTAGACCTATTTTCGAGCTTGTTTTTCATATCGACATCTTACACATCCAGTATACGGTCAGGCCAGGTTGTTGATACAATTGTAATGAATCCTCCATTTGGAACACGACGAAAGGGTGCAGATATGGAATTCCTTTCTGCAGCTTTGAAGGTAATTACAGTTCTGATATCTTACTAGATGCTCAAGTATGTATGTACAACATTTTCTCATTGACTCGTATTCTTTGAAATTTCTTTTCAGCATGCATCCAAAGCCGTTTATTCTTTGCACAAGACCTCAACAAGAGATGTAAGTTCTCACGTTCAAACTCAATGCAAATAAGAACTCTGCACACAGTCACTAAGTCGGGGTTTGTGTTATCTTGTCCGTCCTGTTCATTGCATGGTTGCTATTACTAATGTAGGGGGATGAATGCAGTGGAACAATTATTAACTGCTTCTTTAACCTTGAAAAGCATATTCATGCATCTCACTTTATATGATATTTCCATTTTCTAATTTGAGAATATGGGTTCCATTTGCTAAGAAGTCACGGCTTTCAAAATTTAGCAAATGTAGCTTTCAACAATGAGGAATCTGGTAGTAATTCAATATGTGAAAGGCCCGGTGGTGAAAAAAGGAGACACAGTCTCAATAAATAACTAAGAAGTCATGGCTTCAATCCATCGTGGCCGCCTACCTAGGATTTAATATCCTATAAGTTTTCTTGACACCCAATATTGTAGGGTCAGGGGAGTTGTCTCGTGAGATTAGTCGAGGTATGTGTAAGCTAGCTCGGATACTCACAGATTACATATATTCAATCTGTGAAAGGCCTGGGTTATTTGGATGGTGTAATGTCACTGTGAGTATCTAAATTGTTTAGGAACATGAGCAGATTTAATTTTGTTGAAATACAATCAAATGCTAACCTCTCTAGTTCTTAAAAATGTTTTGTTTTTTGGTTTCTTCCCCCCTAATAATTTCATTGCAACAGCATATAAAACGTGCCGCTTTGCGGGATTATGGCGCCCAAAGTGCTGAGGTTTTGTGTGAGGTGGGTAACAGTTTGTTTGGTTATGTATGCATGTCGGTGTTTGAAGTTTCAATGATATTTATGCTTTCTTCTTGCAGCAGGCTATTCGTGTCTTATTATGATTCAATTTGAACACAAAATCAACCTCTAATTCTAATCTAGCCATTTCTTCTCTTCTTTCTCTTAGCTTCGATACGACGTGCCCCAGCTTTACAAATTTCACAAGAGAAAAGAGATCGACATTGCTGTAGACCTTTGGCGATTTGTACCGAGAAGTCGCCGAGAAAATGGTGTCTAGGACTGACCTACATGAAGTTCATTCCATGTCTTGGACGCGCATAAAGTGATCACATCAAATTTCTGTTGCGAGGAGCCGGATGAGAAGCATCAAATATCTCCTACGATCTTCTTCTGTAGAATGTTCATATATTTCTTGGACACCTCTGCTAAAAGAATTGTGGTACTTGGTTCTTAGGTCTTGGAATTCATTGGAAATTCTTCACCTTTTACCCCGCCATTTTTTGTTTGTTAAGAAAAAAGTGCTTGTTGTTAATGGATATGGAATTTTCATTGTAAAACAGTAACTCTTATGAACAAGAATTGTAATGGTTAAAAAAGGAGGGTAAAACAAATTCGATCAAGCCAATCTAACAATTATTGGCGAAACAATTCATCTGTTTATAGCTTTTATTATTTATTTACTCGTTGATAACGAAAGTCTTACTAGTATTATTGTCCATAGTACTCCAAATAACAAGGCTCAAGTCCCC

mRNA sequence

AAGAGACACGTCCTTTACACTATAGAAGATTGAGAAGAATCAGAGAGGACAAGTCGTGACTTGTTACAGGATATCCTCGCCTTTTTTTCAGAAAGATTAATCCCCTAAATTAGGGTTATCAAGAAAACGGATTCATCAAGATTCTCTCCACCCAACCATGAAGCTCAAGCAATTAGAGTCCTTAATAAGTGAAATTCAACAGTTCTCCAATCCAAAGGTTGAGCTGGAGCAGTATCCCACTGGACCTCACATTGCTTCTCGCATGTTGTACACCGCAGAGAATTCTTTTGGAGATGTGAGTGGCAAGATAGTGGCTGATTTGGGTTGTGGTTGTGGTACATTAGGTGCTGCAGCTGCACTTTTGGGTGCAGAGCATGTTATCGGAATTGACATTGATCCTGAGTCTCTTGAAATAGCATCTTCAAATGCAGACTATCTTGAGTTGGAAATGGACTTGGTTCAGTGCGATGTGAAGAACTTAGGATGGAGAGGTAACAAAATGAAAAACCATAATATGGGTTCTAGTTTTGAAAAAGTATGTTTAGATGAATGTATACTCTGTCCCAGCCAGGTTGTTGATACAATTGTAATGAATCCTCCATTTGGAACACGACGAAAGGGTGCAGATATGGAATTCCTTTCTGCAGCTTTGAAGGTAATTACACATGCATCCAAAGCCGTTTATTCTTTGCACAAGACCTCAACAAGAGATCATATAAAACGTGCCGCTTTGCGGGATTATGGCGCCCAAAGTGCTGAGGTTTTGTGTGAGGTGGCTTCGATACGACGTGCCCCAGCTTTACAAATTTCACAAGAGAAAAGAGATCGACATTGCTGTAGACCTTTGGCGATTTGTACCGAGAAGTCGCCGAGAAAATGGTGTCTAGGACTGACCTACATGAAGTTCATTCCATGTCTTGGACGCGCATAAAGTGATCACATCAAATTTCTGTTGCGAGGAGCCGGATGAGAAGCATCAAATATCTCCTACGATCTTCTTCTGTAGAATGTTCATATATTTCTTGGACACCTCTGCTAAAAGAATTGTGGTACTTGGTTCTTAGGTCTTGGAATTCATTGGAAATTCTTCACCTTTTACCCCGCCATTTTTTGTTTGTTAAGAAAAAAGTGCTTGTTGTTAATGGATATGGAATTTTCATTGTAAAACAGTAACTCTTATGAACAAGAATTGTAATGGTTAAAAAAGGAGGGTAAAACAAATTCGATCAAGCCAATCTAACAATTATTGGCGAAACAATTCATCTGTTTATAGCTTTTATTATTTATTTACTCGTTGATAACGAAAGTCTTACTAGTATTATTGTCCATAGTACTCCAAATAACAAGGCTCAAGTCCCC

Coding sequence (CDS)

ATGAAGCTCAAGCAATTAGAGTCCTTAATAAGTGAAATTCAACAGTTCTCCAATCCAAAGGTTGAGCTGGAGCAGTATCCCACTGGACCTCACATTGCTTCTCGCATGTTGTACACCGCAGAGAATTCTTTTGGAGATGTGAGTGGCAAGATAGTGGCTGATTTGGGTTGTGGTTGTGGTACATTAGGTGCTGCAGCTGCACTTTTGGGTGCAGAGCATGTTATCGGAATTGACATTGATCCTGAGTCTCTTGAAATAGCATCTTCAAATGCAGACTATCTTGAGTTGGAAATGGACTTGGTTCAGTGCGATGTGAAGAACTTAGGATGGAGAGGTAACAAAATGAAAAACCATAATATGGGTTCTAGTTTTGAAAAAGTATGTTTAGATGAATGTATACTCTGTCCCAGCCAGGTTGTTGATACAATTGTAATGAATCCTCCATTTGGAACACGACGAAAGGGTGCAGATATGGAATTCCTTTCTGCAGCTTTGAAGGTAATTACACATGCATCCAAAGCCGTTTATTCTTTGCACAAGACCTCAACAAGAGATCATATAAAACGTGCCGCTTTGCGGGATTATGGCGCCCAAAGTGCTGAGGTTTTGTGTGAGGTGGCTTCGATACGACGTGCCCCAGCTTTACAAATTTCACAAGAGAAAAGAGATCGACATTGCTGTAGACCTTTGGCGATTTGTACCGAGAAGTCGCCGAGAAAATGGTGTCTAGGACTGACCTACATGAAGTTCATTCCATGTCTTGGACGCGCATAA

Protein sequence

MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCGTLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNMGSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHKTSTRDHIKRAALRDYGAQSAEVLCEVASIRRAPALQISQEKRDRHCCRPLAICTEKSPRKWCLGLTYMKFIPCLGRA
Homology
BLAST of CcUC11G210630 vs. NCBI nr
Match: XP_022157590.1 (methyltransferase-like protein 5 [Momordica charantia])

HSP 1 Score: 319.7 bits (818), Expect = 2.3e-83
Identity = 170/206 (82.52%), Postives = 174/206 (84.47%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAALLGAEHV GIDIDPESLEIASSNA+ LELEMDLVQCDVKNLGWRG        
Sbjct: 61  TLGAAAALLGAEHVTGIDIDPESLEIASSNAEDLELEMDLVQCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QVVDTIVMNPPFGTRRKGADMEFLS ALK   HASKAVYSLHK
Sbjct: 121 -----------------QVVDTIVMNPPFGTRRKGADMEFLSVALK---HASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCEL 178

BLAST of CcUC11G210630 vs. NCBI nr
Match: XP_038889166.1 (rRNA N6-adenosine-methyltransferase METTL5 [Benincasa hispida])

HSP 1 Score: 318.5 bits (815), Expect = 5.1e-83
Identity = 169/206 (82.04%), Postives = 174/206 (84.47%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ +IQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG
Sbjct: 1   MKLKQLESLLDQIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAA LLGAEHV GIDID ESLEIASSNA+YLELEMDLVQCDVKNLGWRG        
Sbjct: 61  TLGAAAGLLGAEHVTGIDIDTESLEIASSNAEYLELEMDLVQCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QVVDTIVMNPPFGTRRKGADMEFLSAALK   HASKAVYSLHK
Sbjct: 121 -----------------QVVDTIVMNPPFGTRRKGADMEFLSAALK---HASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLC++
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCQL 178

BLAST of CcUC11G210630 vs. NCBI nr
Match: XP_004139349.1 (methyltransferase-like protein 5 [Cucumis sativus] >KGN60604.1 hypothetical protein Csa_019456 [Cucumis sativus])

HSP 1 Score: 315.1 bits (806), Expect = 5.7e-82
Identity = 164/206 (79.61%), Postives = 174/206 (84.47%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPK++LEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKIQLEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAA+LGAEHV GIDIDP+SLEIASSNA+YLE EMDLV CDVKNLGWRG        
Sbjct: 61  TLGAAAAILGAEHVTGIDIDPDSLEIASSNAEYLEFEMDLVLCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QVVDTIVMNPPFGTRRKGADMEFLSAALK   HASKAVYSLHK
Sbjct: 121 -----------------QVVDTIVMNPPFGTRRKGADMEFLSAALK---HASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAA+RDYGA+SAEVLCE+
Sbjct: 181 TSTRDHIKRAAVRDYGAESAEVLCEL 178

BLAST of CcUC11G210630 vs. NCBI nr
Match: XP_008458526.1 (PREDICTED: methyltransferase-like protein 5 [Cucumis melo])

HSP 1 Score: 313.9 bits (803), Expect = 1.3e-81
Identity = 163/206 (79.13%), Postives = 175/206 (84.95%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPK++LEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKIQLEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAA+LGAEHV GIDIDP+SLEIASSNA+YLE EMDLVQCDVKNLGWRG        
Sbjct: 61  TLGAAAAILGAEHVTGIDIDPDSLEIASSNAEYLEFEMDLVQCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            +VVDTIVMNPPFGTRRKGADMEFLS+ALK   +ASKAVYSLHK
Sbjct: 121 -----------------RVVDTIVMNPPFGTRRKGADMEFLSSALK---YASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGA+SAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAESAEVLCEL 178

BLAST of CcUC11G210630 vs. NCBI nr
Match: XP_022999531.1 (methyltransferase-like protein 5 [Cucurbita maxima])

HSP 1 Score: 311.2 bits (796), Expect = 8.2e-81
Identity = 168/206 (81.55%), Postives = 172/206 (83.50%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLES + EIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG
Sbjct: 1   MKLKQLESFLGEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAALLGAEHV GIDIDPESLEIASSNA+YLELEMDLVQCDVKNL  RG        
Sbjct: 61  TLGAAAALLGAEHVTGIDIDPESLEIASSNAEYLELEMDLVQCDVKNLVLRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QV DTIVMNPPFGTRRKGADMEFLSAALK+   ASKAVYSLHK
Sbjct: 121 -----------------QVFDTIVMNPPFGTRRKGADMEFLSAALKL---ASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCEL 178

BLAST of CcUC11G210630 vs. ExPASy Swiss-Prot
Match: F1QVR8 (rRNA N6-adenosine-methyltransferase METTL5 OS=Danio rerio OX=7955 GN=mettl5 PE=2 SV=1)

HSP 1 Score: 165.2 bits (417), Expect = 9.5e-40
Identity = 93/193 (48.19%), Postives = 121/193 (62.69%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLK+LES + ++  F  PK+ LEQYPT PHIA  MLYT  N+F D+  K+VADLGCGCG
Sbjct: 1   MKLKELESCLQQVDGFEEPKILLEQYPTSPHIAGCMLYTIHNTFDDIQNKLVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLEL-EMDLVQCDVKNLGWRGNKMKNHN 120
            L   AA+L A   +G DID ++L+I   N +  EL  +D+VQCDV ++           
Sbjct: 61  VLSIGAAVLDAGLCVGFDIDEDALDIFRGNVEEFELPNIDVVQCDVCSI----------- 120

Query: 121 MGSSFEKVCLDECILCPSQVVDTIVMNPPFGTR-RKGADMEFLSAALKVITHASKAVYSL 180
            GSS+ K              DT++MNPPFGT+  +G DM+FL  A   I+ A+ AVYSL
Sbjct: 121 -GSSYAK------------KFDTVIMNPPFGTKHNQGIDMQFLQTA---ISMATSAVYSL 166

Query: 181 HKTSTRDHIKRAA 192
           HKTSTRDHI++ A
Sbjct: 181 HKTSTRDHIQKKA 166

BLAST of CcUC11G210630 vs. ExPASy Swiss-Prot
Match: Q8K1A0 (rRNA N6-adenosine-methyltransferase METTL5 OS=Mus musculus OX=10090 GN=Mettl5 PE=2 SV=2)

HSP 1 Score: 163.7 bits (413), Expect = 2.8e-39
Identity = 92/193 (47.67%), Postives = 122/193 (63.21%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           +KLK+LES + E+  F  PK+ LEQYPT PHIA+ MLYT  N++ D+  K VADLGCGCG
Sbjct: 4   LKLKELESRLQEVDGFEKPKLLLEQYPTRPHIAACMLYTIHNTYDDIENKAVADLGCGCG 63

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLEL-EMDLVQCDVKNLGWRGNKMKNHN 120
            L   AA+LGA   +G DID ++LEI + N +  EL  +D++QCDV +L    N+M    
Sbjct: 64  VLSIGAAMLGAGLCVGFDIDEDALEIFNKNVEEFELTNVDMIQCDVYSL---SNRM---- 123

Query: 121 MGSSFEKVCLDECILCPSQVVDTIVMNPPFGTR-RKGADMEFLSAALKVITHASKAVYSL 180
                            S++ DT++MNPPFGT+  KG DM FL  AL +   A  AVYSL
Sbjct: 124 -----------------SKLFDTVIMNPPFGTKNNKGTDMAFLKTALGM---ARTAVYSL 169

Query: 181 HKTSTRDHIKRAA 192
           HK+STR+HI++ A
Sbjct: 184 HKSSTREHIQKKA 169

BLAST of CcUC11G210630 vs. ExPASy Swiss-Prot
Match: Q9NRN9 (rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1)

HSP 1 Score: 161.4 bits (407), Expect = 1.4e-38
Identity = 90/193 (46.63%), Postives = 122/193 (63.21%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           ++LK+LES + ++  F  PK+ LEQYPT PHIA+ MLYT  N++ D+  K+VADLGCGCG
Sbjct: 4   VRLKELESRLQQVDGFEKPKLLLEQYPTRPHIAACMLYTIHNTYDDIENKVVADLGCGCG 63

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLEL-EMDLVQCDVKNLGWRGNKMKNHN 120
            L    A+LGA   +G DID ++LEI + NA+  EL  +D+VQCDV  L        ++ 
Sbjct: 64  VLSIGTAMLGAGLCVGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLL--------SNR 123

Query: 121 MGSSFEKVCLDECILCPSQVVDTIVMNPPFGTR-RKGADMEFLSAALKVITHASKAVYSL 180
           M  SF                DT++MNPPFGT+  KG DM FL  AL++   A  AVYSL
Sbjct: 124 MSKSF----------------DTVIMNPPFGTKNNKGTDMAFLKTALEM---ARTAVYSL 169

Query: 181 HKTSTRDHIKRAA 192
           HK+STR+H+++ A
Sbjct: 184 HKSSTREHVQKKA 169

BLAST of CcUC11G210630 vs. ExPASy Swiss-Prot
Match: Q57732 (Uncharacterized protein MJ0284 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ0284 PE=4 SV=1)

HSP 1 Score: 103.2 bits (256), Expect = 4.4e-21
Identity = 60/187 (32.09%), Postives = 99/187 (52.94%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           +K K LE ++  +++  NPK +LEQY     +A+ +L+ A N F      +V DLGCG G
Sbjct: 2   IKKKHLEMMLDSLKRHPNPKADLEQYTIDGKLAADILFFAVNDF---YNNVVIDLGCGTG 61

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
            L   + +LGA+  IGIDID ES+E A  NA  L +++D    D++++    ++  N+ +
Sbjct: 62  RLAIGSKILGAKRAIGIDIDRESIEAAKENAKKLNVDVDFYCMDIRDV---DDEFLNNVL 121

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
           G                 +   ++ NPPFG ++K AD  FL  AL++       +Y++H 
Sbjct: 122 GED-------------RDLKRVVIQNPPFGAQKKHADRVFLDKALEI----GDIIYTIHN 165

Query: 181 TSTRDHI 188
             T+D +
Sbjct: 182 YPTKDFV 165

BLAST of CcUC11G210630 vs. ExPASy Swiss-Prot
Match: A1U698 (Ribosomal protein L11 methyltransferase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8) OX=351348 GN=prmA PE=3 SV=1)

HSP 1 Score: 61.2 bits (147), Expect = 1.9e-08
Identity = 28/46 (60.87%), Postives = 35/46 (76.09%), Query Frame = 0

Query: 46  DVSGKIVADLGCGCGTLGAAAALLGAEHVIGIDIDPESLEIASSNA 92
           DV+GK V D GCG G LG AA LLGA+HV+G+D DP++LE +  NA
Sbjct: 159 DVAGKQVTDYGCGSGILGLAALLLGADHVVGVDTDPQALEASRDNA 204

BLAST of CcUC11G210630 vs. ExPASy TrEMBL
Match: A0A6J1DTI5 (methyltransferase-like protein 5 OS=Momordica charantia OX=3673 GN=LOC111024243 PE=4 SV=1)

HSP 1 Score: 319.7 bits (818), Expect = 1.1e-83
Identity = 170/206 (82.52%), Postives = 174/206 (84.47%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAALLGAEHV GIDIDPESLEIASSNA+ LELEMDLVQCDVKNLGWRG        
Sbjct: 61  TLGAAAALLGAEHVTGIDIDPESLEIASSNAEDLELEMDLVQCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QVVDTIVMNPPFGTRRKGADMEFLS ALK   HASKAVYSLHK
Sbjct: 121 -----------------QVVDTIVMNPPFGTRRKGADMEFLSVALK---HASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCEL 178

BLAST of CcUC11G210630 vs. ExPASy TrEMBL
Match: A0A0A0LHX0 (MTS domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_2G003070 PE=4 SV=1)

HSP 1 Score: 315.1 bits (806), Expect = 2.7e-82
Identity = 164/206 (79.61%), Postives = 174/206 (84.47%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPK++LEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKIQLEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAA+LGAEHV GIDIDP+SLEIASSNA+YLE EMDLV CDVKNLGWRG        
Sbjct: 61  TLGAAAAILGAEHVTGIDIDPDSLEIASSNAEYLEFEMDLVLCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QVVDTIVMNPPFGTRRKGADMEFLSAALK   HASKAVYSLHK
Sbjct: 121 -----------------QVVDTIVMNPPFGTRRKGADMEFLSAALK---HASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAA+RDYGA+SAEVLCE+
Sbjct: 181 TSTRDHIKRAAVRDYGAESAEVLCEL 178

BLAST of CcUC11G210630 vs. ExPASy TrEMBL
Match: A0A1S3C820 (methyltransferase-like protein 5 OS=Cucumis melo OX=3656 GN=LOC103497905 PE=4 SV=1)

HSP 1 Score: 313.9 bits (803), Expect = 6.1e-82
Identity = 163/206 (79.13%), Postives = 175/206 (84.95%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLESL+ EIQQFSNPK++LEQYPTGPHIASRMLYTAENSFGDVSGK+VADLGCGCG
Sbjct: 1   MKLKQLESLLGEIQQFSNPKIQLEQYPTGPHIASRMLYTAENSFGDVSGKVVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAA+LGAEHV GIDIDP+SLEIASSNA+YLE EMDLVQCDVKNLGWRG        
Sbjct: 61  TLGAAAAILGAEHVTGIDIDPDSLEIASSNAEYLEFEMDLVQCDVKNLGWRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            +VVDTIVMNPPFGTRRKGADMEFLS+ALK   +ASKAVYSLHK
Sbjct: 121 -----------------RVVDTIVMNPPFGTRRKGADMEFLSSALK---YASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGA+SAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAESAEVLCEL 178

BLAST of CcUC11G210630 vs. ExPASy TrEMBL
Match: A0A6J1KDC2 (methyltransferase-like protein 5 OS=Cucurbita maxima OX=3661 GN=LOC111493863 PE=4 SV=1)

HSP 1 Score: 311.2 bits (796), Expect = 4.0e-81
Identity = 168/206 (81.55%), Postives = 172/206 (83.50%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLES + EIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG
Sbjct: 1   MKLKQLESFLGEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAALLGAEHV GIDIDPESLEIASSNA+YLELEMDLVQCDVKNL  RG        
Sbjct: 61  TLGAAAALLGAEHVTGIDIDPESLEIASSNAEYLELEMDLVQCDVKNLVLRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QV DTIVMNPPFGTRRKGADMEFLSAALK+   ASKAVYSLHK
Sbjct: 121 -----------------QVFDTIVMNPPFGTRRKGADMEFLSAALKL---ASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCEL 178

BLAST of CcUC11G210630 vs. ExPASy TrEMBL
Match: A0A6J1G513 (methyltransferase-like protein 5 OS=Cucurbita moschata OX=3662 GN=LOC111450751 PE=4 SV=1)

HSP 1 Score: 307.8 bits (787), Expect = 4.4e-80
Identity = 167/206 (81.07%), Postives = 171/206 (83.01%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLES + EIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG
Sbjct: 1   MKLKQLESFLGEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TLGAAAALLGAEHV GIDIDPESLEIASSNA+ LELEMDLVQCDVKNL  RG        
Sbjct: 61  TLGAAAALLGAEHVTGIDIDPESLEIASSNAESLELEMDLVQCDVKNLVLRG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                            QV DTIVMNPPFGTRRKGADMEFLSAALK+   ASKAVYSLHK
Sbjct: 121 -----------------QVFDTIVMNPPFGTRRKGADMEFLSAALKL---ASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTRDHIKRAALRDYGAQSAEVLCE+
Sbjct: 181 TSTRDHIKRAALRDYGAQSAEVLCEL 178

BLAST of CcUC11G210630 vs. TAIR 10
Match: AT4G28830.1 (S-adenosyl-L-methionine-dependent methyltransferases superfamily protein )

HSP 1 Score: 258.5 bits (659), Expect = 5.9e-69
Identity = 134/206 (65.05%), Postives = 158/206 (76.70%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLE L+ +++QFSNPKVE EQYPTGPHIASRML+TAENS+GD++ K+VAD GCGCG
Sbjct: 1   MKLKQLEGLLGDLEQFSNPKVEFEQYPTGPHIASRMLFTAENSYGDITDKVVADFGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TL AAAALL A  VIG DIDPESLE A+ NA+ LE+E+D VQCD+  L  +G        
Sbjct: 61  TLSAAAALLDAASVIGFDIDPESLETATLNAEELEVEIDFVQCDITKLELKG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                             +VDT+VMNPPFGTR+KGADMEFLSAA+KV   ASKAVYSLHK
Sbjct: 121 -----------------LIVDTVVMNPPFGTRKKGADMEFLSAAMKV---ASKAVYSLHK 178

Query: 181 TSTRDHIKRAALRDYGAQSAEVLCEV 207
           TSTR+HIKRAALRD+ A+SAEV+CE+
Sbjct: 181 TSTREHIKRAALRDFNAKSAEVICEL 178

BLAST of CcUC11G210630 vs. TAIR 10
Match: AT4G28830.2 (S-adenosyl-L-methionine-dependent methyltransferases superfamily protein )

HSP 1 Score: 225.3 bits (573), Expect = 5.5e-59
Identity = 118/185 (63.78%), Postives = 138/185 (74.59%), Query Frame = 0

Query: 1   MKLKQLESLISEIQQFSNPKVELEQYPTGPHIASRMLYTAENSFGDVSGKIVADLGCGCG 60
           MKLKQLE L+ +++QFSNPKVE EQYPTGPHIASRML+TAENS+GD++ K+VAD GCGCG
Sbjct: 1   MKLKQLEGLLGDLEQFSNPKVEFEQYPTGPHIASRMLFTAENSYGDITDKVVADFGCGCG 60

Query: 61  TLGAAAALLGAEHVIGIDIDPESLEIASSNADYLELEMDLVQCDVKNLGWRGNKMKNHNM 120
           TL AAAALL A  VIG DIDPESLE A+ NA+ LE+E+D VQCD+  L  +G        
Sbjct: 61  TLSAAAALLDAASVIGFDIDPESLETATLNAEELEVEIDFVQCDITKLELKG-------- 120

Query: 121 GSSFEKVCLDECILCPSQVVDTIVMNPPFGTRRKGADMEFLSAALKVITHASKAVYSLHK 180
                             +VDT+VMNPPFGTR+KGADMEFLSAA+KV   ASKAVYSLHK
Sbjct: 121 -----------------LIVDTVVMNPPFGTRKKGADMEFLSAAMKV---ASKAVYSLHK 157

Query: 181 TSTRD 186
           TSTR+
Sbjct: 181 TSTRE 157

The following BLAST results are available for this feature:
Match NameE-valueIdentityDescription
XP_022157590.12.3e-8382.52methyltransferase-like protein 5 [Momordica charantia][more]
XP_038889166.15.1e-8382.04rRNA N6-adenosine-methyltransferase METTL5 [Benincasa hispida][more]
XP_004139349.15.7e-8279.61methyltransferase-like protein 5 [Cucumis sativus] >KGN60604.1 hypothetical prot... [more]
XP_008458526.11.3e-8179.13PREDICTED: methyltransferase-like protein 5 [Cucumis melo][more]
XP_022999531.18.2e-8181.55methyltransferase-like protein 5 [Cucurbita maxima][more]
Match NameE-valueIdentityDescription
F1QVR89.5e-4048.19rRNA N6-adenosine-methyltransferase METTL5 OS=Danio rerio OX=7955 GN=mettl5 PE=2... [more]
Q8K1A02.8e-3947.67rRNA N6-adenosine-methyltransferase METTL5 OS=Mus musculus OX=10090 GN=Mettl5 PE... [more]
Q9NRN91.4e-3846.63rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=... [more]
Q577324.4e-2132.09Uncharacterized protein MJ0284 OS=Methanocaldococcus jannaschii (strain ATCC 430... [more]
A1U6981.9e-0860.87Ribosomal protein L11 methyltransferase OS=Marinobacter hydrocarbonoclasticus (s... [more]
Match NameE-valueIdentityDescription
A0A6J1DTI51.1e-8382.52methyltransferase-like protein 5 OS=Momordica charantia OX=3673 GN=LOC111024243 ... [more]
A0A0A0LHX02.7e-8279.61MTS domain-containing protein OS=Cucumis sativus OX=3659 GN=Csa_2G003070 PE=4 SV... [more]
A0A1S3C8206.1e-8279.13methyltransferase-like protein 5 OS=Cucumis melo OX=3656 GN=LOC103497905 PE=4 SV... [more]
A0A6J1KDC24.0e-8181.55methyltransferase-like protein 5 OS=Cucurbita maxima OX=3661 GN=LOC111493863 PE=... [more]
A0A6J1G5134.4e-8081.07methyltransferase-like protein 5 OS=Cucurbita moschata OX=3662 GN=LOC111450751 P... [more]
Match NameE-valueIdentityDescription
AT4G28830.15.9e-6965.05S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [more]
AT4G28830.25.5e-5963.78S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [more]
InterPro
Analysis Name: InterPro Annotations of Watermelon (PI 537277) v1
Date Performed: 2022-01-31
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D3.40.50.150Vaccinia Virus protein VP39coord: 1..222
e-value: 3.1E-56
score: 191.9
NoneNo IPR availablePFAMPF06325PrmAcoord: 28..98
e-value: 2.6E-11
score: 43.5
NoneNo IPR availablePANTHERPTHR23290UNCHARACTERIZEDcoord: 1..124
coord: 137..206
NoneNo IPR availablePANTHERPTHR23290:SF5BNAA03G59050D PROTEINcoord: 1..124
NoneNo IPR availablePANTHERPTHR23290:SF5BNAA03G59050D PROTEINcoord: 137..206
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 52..180
e-value: 8.34925E-5
score: 38.9503
IPR002052DNA methylase, N-6 adenine-specific, conserved sitePROSITEPS00092N6_MTASEcoord: 143..149
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILY53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 9..170

Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
CcUC11G210630.1CcUC11G210630.1mRNA


GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0032259 methylation
molecular_function GO:0008168 methyltransferase activity
molecular_function GO:0003676 nucleic acid binding