CcUC02G025910 (gene) Watermelon (PI 537277) v1

Overview


Name	CcUC02G025910
Type	gene
Organism	Citrullus colocynthis (Watermelon (PI 537277) v1)
Description	Cyclin
Location	CicolChr02: 11076376 .. 11077329 (+)
RNA-Seq Expression	CcUC02G025910
Synteny	CcUC02G025910

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRCDSpolypeptidethree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

TCAAAACCATTAACCTCTCTCATTCCTTTCCAACCCAGCGGAGCCATTTATCAAATAATAATGTTGACCGGCAGCGACTTCGCAACTCCGGGCAGAGTGGAGGGCGATAACACGGCCGAGCCAACGCCAAGAGTGCTCATCATATTAGCCTTCGTCCTGGACCGACTCGTGGCTCGTAACGACTGTCTCGTAAATGGGGTGAGCCAGAGTCATCAGCTGGAAGAGTTAGGGTGCTGTAGCTCTTCCTCTAGACATTTAGGAAACAGCTTCAATGCATTCCATGGAGTCCGAGCTCCCACTATTTCTATATTGAAATACTTGGAGAGAATTTACAAATACACCAATTGTAGCCCTTCTTGCCTTGTGGTTGGATTTGTTTATATCGATAGATTGATCCATCGACACCCCGACTCGCTTGTCATCTCCTTGAATGTTCATCGCCTTGTCGTGACTAGTGTCATGGTTGCCTCTAAGATGCTCGACGACGTGTGAGAGTCTCTATATAACCCACATCTAGTTAATTGTTTAAGAGTATGTTTGAAATGATTTTTTTTTTCCTTTAACGGTTGACAGGCATTACAACAACGCATTTTACGCGCGAGTGGGAGGGGTGAGCAAAGCAGAGCTGAATAAGTTGGAATTGGAAATGCTTTTTTTGTTGGATTTTAAGGTGACGGTTAGTTCAAGGGCTTTTGAAACTTATTGCTGGCATTTGGAGAAAGAGATGTTATTGAATGGCAATGGGGAGATGCAAAGAGCGGAAAGACCGTTGATGCCTACTAATAGTTTGGACGACGTGTCAGAAATTTCAGTGGACGACACTCTTGTTTCTTCTTCGCCTCCTTGATTATATTCATTGTTTTCTTCTCCTCTTCTCTGCTTATTCAGATATAATTTTGCTTATACGGTGCCTGAGTTAATGCTTGTTTCCTTCTTCGACAATTTAATTACGGG

mRNA sequence

TCAAAACCATTAACCTCTCTCATTCCTTTCCAACCCAGCGGAGCCATTTATCAAATAATAATGTTGACCGGCAGCGACTTCGCAACTCCGGGCAGAGTGGAGGGCGATAACACGGCCGAGCCAACGCCAAGAGTGCTCATCATATTAGCCTTCGTCCTGGACCGACTCGTGGCTCGTAACGACTGTCTCGTAAATGGGGTGAGCCAGAGTCATCAGCTGGAAGAGTTAGGGTGCTGTAGCTCTTCCTCTAGACATTTAGGAAACAGCTTCAATGCATTCCATGGAGTCCGAGCTCCCACTATTTCTATATTGAAATACTTGGAGAGAATTTACAAATACACCAATTGTAGCCCTTCTTGCCTTGTGGTTGGATTTGTTTATATCGATAGATTGATCCATCGACACCCCGACTCGCTTGTCATCTCCTTGAATGTTCATCGCCTTGTCGTGACTAGTGTCATGGTTGCCTCTAAGATGCTCGACGACGTGCATTACAACAACGCATTTTACGCGCGAGTGGGAGGGGTGAGCAAAGCAGAGCTGAATAAGTTGGAATTGGAAATGCTTTTTTTGTTGGATTTTAAGGTGACGGTTAGTTCAAGGGCTTTTGAAACTTATTGCTGGCATTTGGAGAAAGAGATGTTATTGAATGGCAATGGGGAGATGCAAAGAGCGGAAAGACCGTTGATGCCTACTAATAGTTTGGACGACGTGTCAGAAATTTCAGTGGACGACACTCTTGTTTCTTCTTCGCCTCCTTGATTATATTCATTGTTTTCTTCTCCTCTTCTCTGCTTATTCAGATATAATTTTGCTTATACGGTGCCTGAGTTAATGCTTGTTTCCTTCTTCGACAATTTAATTACGGG

Coding sequence (CDS)

ATGTTGACCGGCAGCGACTTCGCAACTCCGGGCAGAGTGGAGGGCGATAACACGGCCGAGCCAACGCCAAGAGTGCTCATCATATTAGCCTTCGTCCTGGACCGACTCGTGGCTCGTAACGACTGTCTCGTAAATGGGGTGAGCCAGAGTCATCAGCTGGAAGAGTTAGGGTGCTGTAGCTCTTCCTCTAGACATTTAGGAAACAGCTTCAATGCATTCCATGGAGTCCGAGCTCCCACTATTTCTATATTGAAATACTTGGAGAGAATTTACAAATACACCAATTGTAGCCCTTCTTGCCTTGTGGTTGGATTTGTTTATATCGATAGATTGATCCATCGACACCCCGACTCGCTTGTCATCTCCTTGAATGTTCATCGCCTTGTCGTGACTAGTGTCATGGTTGCCTCTAAGATGCTCGACGACGTGCATTACAACAACGCATTTTACGCGCGAGTGGGAGGGGTGAGCAAAGCAGAGCTGAATAAGTTGGAATTGGAAATGCTTTTTTTGTTGGATTTTAAGGTGACGGTTAGTTCAAGGGCTTTTGAAACTTATTGCTGGCATTTGGAGAAAGAGATGTTATTGAATGGCAATGGGGAGATGCAAAGAGCGGAAAGACCGTTGATGCCTACTAATAGTTTGGACGACGTGTCAGAAATTTCAGTGGACGACACTCTTGTTTCTTCTTCGCCTCCTTGA

Protein sequence

MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLLNGNGEMQRAERPLMPTNSLDDVSEISVDDTLVSSSPP

Homology

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BLAST of CcUC02G025910 vs. NCBI nr
Match: XP_038901956.1 (cyclin-U1-1 [Benincasa hispida])

HSP 1 Score: 435.3 bits (1118), Expect = 3.4e-118
Identity = 216/233 (92.70%), Postives = 220/233 (94.42%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTGSDFA PGR EGDN AEPTPRVLIILAFVLDRLVARND L+NGVSQS QLEE GCCS
Sbjct: 1   MLTGSDFAAPGRAEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNGVSQSRQLEESGCCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
            SS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSL+
Sbjct: 61  PSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLI 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTS+MVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSIMVASKMLDDVHYNNAFYARVGGVSKVELNKLELEMLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPLMPTNSLDDVSEISVDDTLVSSSPP 234
           R FETYCWHLEKEMLLNGNGEMQR ERPLMPTNSLDDVSEISVDDTL SSSPP
Sbjct: 181 RVFETYCWHLEKEMLLNGNGEMQRMERPLMPTNSLDDVSEISVDDTLASSSPP 233

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BLAST of CcUC02G025910 vs. NCBI nr
Match: KAE8652302.1 (hypothetical protein Csa_022481 [Cucumis sativus])

HSP 1 Score: 422.5 bits (1085), Expect = 2.3e-114
Identity = 218/235 (92.77%), Postives = 222/235 (94.47%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTGSDFA PGRVEGDN AEPTPRVLIILAFVLDRLVARND L+N +SQ  QLEELGCCS
Sbjct: 65  MLTGSDFAAPGRVEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELSQ--QLEELGCCS 124

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 125 SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 184

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 185 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 244

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           R FETYCWHLEKEMLLNGNGEMQR ERPL MPTN+LDDVSEISVDDT LVSSSPP
Sbjct: 245 RVFETYCWHLEKEMLLNGNGEMQRVERPLIMPTNTLDDVSEISVDDTLLVSSSPP 297

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BLAST of CcUC02G025910 vs. NCBI nr
Match: XP_004151930.2 (cyclin-U1-1 [Cucumis sativus])

HSP 1 Score: 422.5 bits (1085), Expect = 2.3e-114
Identity = 218/235 (92.77%), Postives = 222/235 (94.47%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTGSDFA PGRVEGDN AEPTPRVLIILAFVLDRLVARND L+N +SQ  QLEELGCCS
Sbjct: 57  MLTGSDFAAPGRVEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELSQ--QLEELGCCS 116

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 117 SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 176

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 177 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 236

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           R FETYCWHLEKEMLLNGNGEMQR ERPL MPTN+LDDVSEISVDDT LVSSSPP
Sbjct: 237 RVFETYCWHLEKEMLLNGNGEMQRVERPLIMPTNTLDDVSEISVDDTLLVSSSPP 289

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BLAST of CcUC02G025910 vs. NCBI nr
Match: XP_008455834.1 (PREDICTED: cyclin-U1-1 [Cucumis melo] >KAA0042430.1 cyclin-U1-1 [Cucumis melo var. makuwa] >TYJ98312.1 cyclin-U1-1 [Cucumis melo var. makuwa])

HSP 1 Score: 412.9 bits (1060), Expect = 1.8e-111
Identity = 214/235 (91.06%), Postives = 220/235 (93.62%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DFA PGR EGDN AEPTPRVLIILAFVLDRLVARND L+N ++Q  QLEELGCCS
Sbjct: 1   MLTGNDFAAPGRAEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELTQ--QLEELGCCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 61  SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           RAFETYC HLEKEMLLNGNGEMQR ERPL MPTN+LDDV EISVDDT LVSSSPP
Sbjct: 181 RAFETYCCHLEKEMLLNGNGEMQRVERPLVMPTNTLDDVLEISVDDTLLVSSSPP 233

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BLAST of CcUC02G025910 vs. NCBI nr
Match: KAG6604845.1 (Cyclin-U1-1, partial [Cucurbita argyrosperma subsp. sororia])

HSP 1 Score: 387.1 bits (993), Expect = 1.1e-103
Identity = 197/233 (84.55%), Postives = 212/233 (90.99%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DF   G  EGDN AEPTPRVLIILA VLDRLVARND +V+G+  +HQ+EE   CS
Sbjct: 1   MLTGNDFPANGLAEGDNVAEPTPRVLIILACVLDRLVARNDRIVDGI--THQIEESSSCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           +S  H+GNSFNAFHGVRAP ISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHP+SLV
Sbjct: 61  TS--HIGNSFNAFHGVRAPAISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPNSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASK+LDDVHYNNAFYARVGGV+KAELNKLELE+LFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSVMVASKILDDVHYNNAFYARVGGVNKAELNKLELELLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPLMPTNSLDDVSEISVDDTLVSSSPP 234
           RAFETYC HLEKEMLLNGNGE+QR ERP+M TNSLDDVSEISVDDTL SSSPP
Sbjct: 181 RAFETYCLHLEKEMLLNGNGELQRIERPIMATNSLDDVSEISVDDTLASSSPP 229

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BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot
Match: Q9LJ45 (Cyclin-U1-1 OS=Arabidopsis thaliana OX=3702 GN=CYCU1-1 PE=1 SV=1)

HSP 1 Score: 236.9 bits (603), Expect = 2.3e-61
Identity = 126/224 (56.25%), Postives = 156/224 (69.64%), Query Frame = 0


Query: 1   MLT--GSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGC 60
           MLT  G D   P       T   TPRVL I++ V+++LVARN+ L               
Sbjct: 1   MLTAAGDDELDPVVGPESATEAATPRVLTIISHVMEKLVARNEWL--------------- 60

Query: 61  CSSSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDS 120
            +  ++  G S  AFHGVRAP+ISI KYLERIYKYT CSP+C VVG+VYIDRL H+HP S
Sbjct: 61  -AKQTKGFGKSLEAFHGVRAPSISIAKYLERIYKYTKCSPACFVVGYVYIDRLAHKHPGS 120

Query: 121 LVISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTV 180
           LV+SLNVHRL+VT VM+A+K+LDDVHYNN FYARVGGVS A+LNK+ELE+LFLLDF+VTV
Sbjct: 121 LVVSLNVHRLLVTCVMIAAKILDDVHYNNEFYARVGGVSNADLNKMELELLFLLDFRVTV 180

Query: 181 SSRAFETYCWHLEKEMLLN----GNGEMQRAERPLMPTNSLDDV 219
           S R FE+YC+HLEKEM LN       ++Q  +  L P ++L  +
Sbjct: 181 SFRVFESYCFHLEKEMQLNDAVSSLKDIQPMQESLSPASTLSSL 208

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BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot
Match: O80513 (Cyclin-U4-1 OS=Arabidopsis thaliana OX=3702 GN=CYCU4-1 PE=1 SV=1)

HSP 1 Score: 159.5 bits (402), Expect = 4.7e-38
Identity = 80/165 (48.48%), Postives = 109/165 (66.06%), Query Frame = 0


Query: 32  VLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRAPTISILKYLERIY 91
           V+ +L+A    L+  V++S+ L       S         + FHG+  PTI+I  YLERI+
Sbjct: 9   VMSKLIAFLSSLLERVAESNDLTRRVATQS------QRVSVFHGLSRPTITIQSYLERIF 68

Query: 92  KYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASKMLDDVHYNNAFYA 151
           KY NCSPSC VV +VY+DR  HR P   + S NVHRL++TSVMVA+K LDD++YNNA+YA
Sbjct: 69  KYANCSPSCFVVAYVYLDRFTHRQPSLPINSFNVHRLLITSVMVAAKFLDDLYYNNAYYA 128

Query: 152 RVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLL 197
           +VGG+S  E+N LEL+ LF L F++ V+   F  Y  +L+KEM L
Sbjct: 129 KVGGISTKEMNFLELDFLFGLGFELNVTPNTFNAYFSYLQKEMTL 167

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BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot
Match: Q0J9W0 (Cyclin-P1-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP1-1 PE=3 SV=2)

HSP 1 Score: 156.8 bits (395), Expect = 3.1e-37
Identity = 84/183 (45.90%), Postives = 114/183 (62.30%), Query Frame = 0


Query: 21  PTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLG---NSFNAFHGVR 80
           P P  L ++A  + RLVARND           +E L     ++  LG    +F A  G  
Sbjct: 21  PPPPELDMVARAVQRLVARNDA----------VEALSGGGEAAAGLGAGMAAFEAARGAP 80

Query: 81  APTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVAS 140
           AP I + +YLER+++Y    P C VV + Y+D   HR P + V S NVHRL++  ++VAS
Sbjct: 81  APRIGVAQYLERVHRYAGLEPECYVVAYAYVDMAAHRRPAAAVASRNVHRLLLACLLVAS 140

Query: 141 KMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLLN 200
           K+LDD H+NNAF+ARVGGVS AE+N+LELE+L +LDF+V +S R +E Y  HLEKE   +
Sbjct: 141 KVLDDFHHNNAFFARVGGVSNAEMNRLELELLAVLDFEVMLSHRVYELYREHLEKEARRD 193

[Close]

BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot
Match: Q75HV0 (Cyclin-P3-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP3-1 PE=3 SV=1)

HSP 1 Score: 155.2 bits (391), Expect = 8.9e-37
Identity = 83/208 (39.90%), Postives = 128/208 (61.54%), Query Frame = 0


Query: 23  PRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRAPTIS 82
           P+VL++LA  LDR V +N+ L++                 S  + +S   FHG RAP +S
Sbjct: 36  PKVLLLLAAYLDRSVQKNEDLLD-----------------SNKIKDSSTIFHGHRAPDLS 95

Query: 83  ILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASKMLDD 142
           I  Y ERI+KY+ CSPSC V+  +Y++R + + P   + SL+VHRL++TSV+VA+K  DD
Sbjct: 96  IKLYAERIFKYSECSPSCFVLALIYMERYL-QQPHVYMTSLSVHRLLITSVVVAAKFTDD 155

Query: 143 VHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLLNGNGEM 202
             +NNAFYARVGG+S  E+N+LEL++LF LDF++ V    F +YC  LEKE +      +
Sbjct: 156 AFFNNAFYARVGGISTVEMNRLELDLLFNLDFRLKVDLETFGSYCLQLEKETM------V 215

Query: 203 QRAERPLMPTNSLDDVSEISVDDTLVSS 231
              +RP+   + ++   ++S + ++  S
Sbjct: 216 LVIDRPIQQVHGVNSTKDLSRNSSIDES 219

[Close]

BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot
Match: Q7XC35 (Cyclin-P4-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP4-1 PE=2 SV=1)

HSP 1 Score: 149.4 bits (376), Expect = 4.9e-35
Identity = 76/176 (43.18%), Postives = 108/176 (61.36%), Query Frame = 0


Query: 19  AEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRA 78
           AE  PRV+ IL+ +L R+  RND      +   +                + +AF G+  
Sbjct: 7   AEAVPRVVAILSSLLQRVAERNDAAAAAAAVGEE--------------AAAVSAFQGLTK 66

Query: 79  PTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASK 138
           P ISI  YLERI+++ NCSPSC VV ++Y+DR + R P   V S NVHRL++TSV+ A K
Sbjct: 67  PAISIGGYLERIFRFANCSPSCYVVAYIYLDRFLRRRPALAVDSFNVHRLLITSVLTAVK 126

Query: 139 MLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEM 195
            +DD+ YNNA++ARVGG+S  E+N LE++ LF + F + V+  AF +YC  L+ EM
Sbjct: 127 FVDDICYNNAYFARVGGISLMEMNYLEVDFLFGIAFDLNVTPAAFASYCAVLQSEM 168

[Close]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL
Match: A0A0A0LQH0 (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G422050 PE=3 SV=1)

HSP 1 Score: 422.5 bits (1085), Expect = 1.1e-114
Identity = 218/235 (92.77%), Postives = 222/235 (94.47%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTGSDFA PGRVEGDN AEPTPRVLIILAFVLDRLVARND L+N +SQ  QLEELGCCS
Sbjct: 1   MLTGSDFAAPGRVEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELSQ--QLEELGCCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 61  SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           R FETYCWHLEKEMLLNGNGEMQR ERPL MPTN+LDDVSEISVDDT LVSSSPP
Sbjct: 181 RVFETYCWHLEKEMLLNGNGEMQRVERPLIMPTNTLDDVSEISVDDTLLVSSSPP 233

[Close]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL
Match: A0A5D3BEZ8 (Cyclin-U1-1 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold232G00280 PE=3 SV=1)

HSP 1 Score: 412.9 bits (1060), Expect = 8.8e-112
Identity = 214/235 (91.06%), Postives = 220/235 (93.62%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DFA PGR EGDN AEPTPRVLIILAFVLDRLVARND L+N ++Q  QLEELGCCS
Sbjct: 1   MLTGNDFAAPGRAEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELTQ--QLEELGCCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 61  SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           RAFETYC HLEKEMLLNGNGEMQR ERPL MPTN+LDDV EISVDDT LVSSSPP
Sbjct: 181 RAFETYCCHLEKEMLLNGNGEMQRVERPLVMPTNTLDDVLEISVDDTLLVSSSPP 233

[Close]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL
Match: A0A1S3C1Y7 (cyclin-U1-1 OS=Cucumis melo OX=3656 GN=LOC103495936 PE=3 SV=1)

HSP 1 Score: 412.9 bits (1060), Expect = 8.8e-112
Identity = 214/235 (91.06%), Postives = 220/235 (93.62%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DFA PGR EGDN AEPTPRVLIILAFVLDRLVARND L+N ++Q  QLEELGCCS
Sbjct: 1   MLTGNDFAAPGRAEGDNAAEPTPRVLIILAFVLDRLVARNDRLLNELTQ--QLEELGCCS 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           SSS HLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV
Sbjct: 61  SSSNHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTSVMVASKMLDDVHYNNAFYARVGGVSK ELNKLELEMLFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSVMVASKMLDDVHYNNAFYARVGGVSKGELNKLELEMLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPL-MPTNSLDDVSEISVDDT-LVSSSPP 234
           RAFETYC HLEKEMLLNGNGEMQR ERPL MPTN+LDDV EISVDDT LVSSSPP
Sbjct: 181 RAFETYCCHLEKEMLLNGNGEMQRVERPLVMPTNTLDDVLEISVDDTLLVSSSPP 233

[Close]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL
Match: A0A6J1G7K4 (Cyclin OS=Cucurbita moschata OX=3662 GN=LOC111451542 PE=3 SV=1)

HSP 1 Score: 384.4 bits (986), Expect = 3.3e-103
Identity = 195/233 (83.69%), Postives = 210/233 (90.13%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DF   G  EGDN AEPTPRVLIILA VLDRLVARND +V+G+  +HQ+EE   C 
Sbjct: 1   MLTGNDFPANGLAEGDNVAEPTPRVLIILACVLDRLVARNDRIVDGI--THQIEESSSCG 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           +S  H+GNSFNAFHGVRAP ISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHP+SLV
Sbjct: 61  TS--HIGNSFNAFHGVRAPAISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPNSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLN+HRL+VTSVMVASK+LDDVHYNNAFYARVGGV+K ELNKLELE+LFLLDF VTVSS
Sbjct: 121 ISLNIHRLLVTSVMVASKILDDVHYNNAFYARVGGVNKVELNKLELELLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPLMPTNSLDDVSEISVDDTLVSSSPP 234
           RAFETYC HLEKEMLLNGNGE+QR ERPLM TNSLDDVSEISVDDTL SSSPP
Sbjct: 181 RAFETYCLHLEKEMLLNGNGELQRIERPLMATNSLDDVSEISVDDTLASSSPP 229

[Close]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL
Match: A0A6J1I5U7 (Cyclin OS=Cucurbita maxima OX=3661 GN=LOC111469864 PE=3 SV=1)

HSP 1 Score: 382.9 bits (982), Expect = 9.7e-103
Identity = 194/233 (83.26%), Postives = 209/233 (89.70%), Query Frame = 0


Query: 1   MLTGSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCS 60
           MLTG+DF   G  EGDN AEPTPRVLIILA VLDRLVARND + +G+  +HQ+EE   C 
Sbjct: 1   MLTGNDFPANGLAEGDNVAEPTPRVLIILACVLDRLVARNDRIADGI--THQIEESSSCG 60

Query: 61  SSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLV 120
           +S  H+GNSFNAFHGVRAP ISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHP+SLV
Sbjct: 61  TS--HIGNSFNAFHGVRAPAISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPNSLV 120

Query: 121 ISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSS 180
           ISLNVHRL+VTS+MVASK+LDDVHYNNAFYARVGGV+K ELNKLELE+LFLLDF VTVSS
Sbjct: 121 ISLNVHRLLVTSIMVASKILDDVHYNNAFYARVGGVNKVELNKLELELLFLLDFGVTVSS 180

Query: 181 RAFETYCWHLEKEMLLNGNGEMQRAERPLMPTNSLDDVSEISVDDTLVSSSPP 234
           RAFETYC HLEKEMLLNGNGE+QR ERPLM TNSLDDVSEISVDDTL SSSPP
Sbjct: 181 RAFETYCLHLEKEMLLNGNGELQRIERPLMATNSLDDVSEISVDDTLASSSPP 229

[Close]

BLAST of CcUC02G025910 vs. TAIR 10
Match: AT3G21870.1 (cyclin p2;1 )

HSP 1 Score: 236.9 bits (603), Expect = 1.7e-62
Identity = 126/224 (56.25%), Postives = 156/224 (69.64%), Query Frame = 0


Query: 1   MLT--GSDFATPGRVEGDNTAEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGC 60
           MLT  G D   P       T   TPRVL I++ V+++LVARN+ L               
Sbjct: 1   MLTAAGDDELDPVVGPESATEAATPRVLTIISHVMEKLVARNEWL--------------- 60

Query: 61  CSSSSRHLGNSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDS 120
            +  ++  G S  AFHGVRAP+ISI KYLERIYKYT CSP+C VVG+VYIDRL H+HP S
Sbjct: 61  -AKQTKGFGKSLEAFHGVRAPSISIAKYLERIYKYTKCSPACFVVGYVYIDRLAHKHPGS 120

Query: 121 LVISLNVHRLVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTV 180
           LV+SLNVHRL+VT VM+A+K+LDDVHYNN FYARVGGVS A+LNK+ELE+LFLLDF+VTV
Sbjct: 121 LVVSLNVHRLLVTCVMIAAKILDDVHYNNEFYARVGGVSNADLNKMELELLFLLDFRVTV 180

Query: 181 SSRAFETYCWHLEKEMLLN----GNGEMQRAERPLMPTNSLDDV 219
           S R FE+YC+HLEKEM LN       ++Q  +  L P ++L  +
Sbjct: 181 SFRVFESYCFHLEKEMQLNDAVSSLKDIQPMQESLSPASTLSSL 208

[Close]

BLAST of CcUC02G025910 vs. TAIR 10
Match: AT2G44740.1 (cyclin p4;1 )

HSP 1 Score: 159.5 bits (402), Expect = 3.4e-39
Identity = 80/165 (48.48%), Postives = 109/165 (66.06%), Query Frame = 0


Query: 32  VLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRAPTISILKYLERIY 91
           V+ +L+A    L+  V++S+ L       S         + FHG+  PTI+I  YLERI+
Sbjct: 9   VMSKLIAFLSSLLERVAESNDLTRRVATQS------QRVSVFHGLSRPTITIQSYLERIF 68

Query: 92  KYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASKMLDDVHYNNAFYA 151
           KY NCSPSC VV +VY+DR  HR P   + S NVHRL++TSVMVA+K LDD++YNNA+YA
Sbjct: 69  KYANCSPSCFVVAYVYLDRFTHRQPSLPINSFNVHRLLITSVMVAAKFLDDLYYNNAYYA 128

Query: 152 RVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLL 197
           +VGG+S  E+N LEL+ LF L F++ V+   F  Y  +L+KEM L
Sbjct: 129 KVGGISTKEMNFLELDFLFGLGFELNVTPNTFNAYFSYLQKEMTL 167

[Close]

BLAST of CcUC02G025910 vs. TAIR 10
Match: AT5G61650.1 (CYCLIN P4;2 )

HSP 1 Score: 142.5 bits (358), Expect = 4.3e-34
Identity = 71/178 (39.89%), Postives = 110/178 (61.80%), Query Frame = 0


Query: 19  AEPTPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRA 78
           AE  P VL  ++++L R+   ND     +SQ  +                  ++F GV  
Sbjct: 19  AEIMPSVLTAMSYLLQRVSETND----NLSQKQKP-----------------SSFTGVTK 78

Query: 79  PTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASK 138
           P+ISI  YLERI++Y NCS SC +V ++Y+DR + + P   + S NVHRL++TSV+V++K
Sbjct: 79  PSISIRSYLERIFEYANCSYSCYIVAYIYLDRFVKKQPFLPINSFNVHRLIITSVLVSAK 138

Query: 139 MLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLL 197
            +DD+ YNN +YA+VGG+S+ E+N LEL+ LF + F++ V+   F  YC  L++EM +
Sbjct: 139 FMDDLSYNNEYYAKVGGISREEMNMLELDFLFGIGFELNVTVSTFNNYCCFLQREMAM 175

[Close]

BLAST of CcUC02G025910 vs. TAIR 10
Match: AT3G63120.1 (cyclin p1;1 )

HSP 1 Score: 141.7 bits (356), Expect = 7.3e-34
Identity = 66/126 (52.38%), Postives = 93/126 (73.81%), Query Frame = 0


Query: 68  NSFNAFHGVRAPTISILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHR 127
           +S   F G   P ISI  YL+RI+KY+ CSPSC V+  +YID  +H+   +L+  LNVHR
Sbjct: 60  DSVTVFDGRSPPEISIAHYLDRIFKYSCCSPSCFVIAHIYIDHFLHK-TRALLKPLNVHR 119

Query: 128 LVVTSVMVASKMLDDVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYC 187
           L++T+VM+A+K+ DD ++NNA+YARVGGV+  ELN+LE+E+LF LDFK+ V  + F T+C
Sbjct: 120 LIITTVMLAAKVFDDRYFNNAYYARVGGVTTRELNRLEMELLFTLDFKLQVDPQTFHTHC 179

Query: 188 WHLEKE 194
             LEK+
Sbjct: 180 CQLEKQ 184

[Close]

BLAST of CcUC02G025910 vs. TAIR 10
Match: AT3G60550.1 (cyclin p3;2 )

HSP 1 Score: 139.4 bits (350), Expect = 3.6e-33
Identity = 71/186 (38.17%), Postives = 111/186 (59.68%), Query Frame = 0


Query: 22  TPRVLIILAFVLDRLVARNDCLVNGVSQSHQLEELGCCSSSSRHLGNSFNAFHGVRAPTI 81
           TP V+ +L+ ++DR + RN             E +   +  S   G     F     P +
Sbjct: 29  TPLVISVLSSLIDRTLTRN-------------ERISRRALPSSGAGGKTQIFDCREIPDM 88

Query: 82  SILKYLERIYKYTNCSPSCLVVGFVYIDRLIHRHPDSLVISLNVHRLVVTSVMVASKMLD 141
           +I  YL RI++YT   PS  VV +VYIDR    +P   +   NVHRL++T++M+ASK ++
Sbjct: 89  TIQSYLGRIFRYTKAGPSVYVVAYVYIDRFCQTNPGFRISLTNVHRLLITTIMIASKYVE 148

Query: 142 DVHYNNAFYARVGGVSKAELNKLELEMLFLLDFKVTVSSRAFETYCWHLEKEMLLNGNGE 201
           D++Y N+++A+VGG+   +LNKLELE LFL+ FK+ V+   FE+YC HLE+E+   G  +
Sbjct: 149 DLNYRNSYFAKVGGLETEDLNKLELEFLFLMGFKLHVNVSVFESYCCHLEREVSFGGGYQ 201

Query: 202 MQRAER 208
           +++A R
Sbjct: 209 IEKALR 201

The following BLAST results are available for this feature:

BLAST of CcUC02G025910 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_038901956.1	3.4e-118	92.70	cyclin-U1-1 [Benincasa hispida]	[more]
KAE8652302.1	2.3e-114	92.77	hypothetical protein Csa_022481 [Cucumis sativus]	[more]
XP_004151930.2	2.3e-114	92.77	cyclin-U1-1 [Cucumis sativus]	[more]
XP_008455834.1	1.8e-111	91.06	PREDICTED: cyclin-U1-1 [Cucumis melo] >KAA0042430.1 cyclin-U1-1 [Cucumis melo va...	[more]
KAG6604845.1	1.1e-103	84.55	Cyclin-U1-1, partial [Cucurbita argyrosperma subsp. sororia]	[more]

BLAST of CcUC02G025910 vs. ExPASy Swiss-Prot


Match Name	E-value	Identity	Description
Q9LJ45	2.3e-61	56.25	Cyclin-U1-1 OS=Arabidopsis thaliana OX=3702 GN=CYCU1-1 PE=1 SV=1	[more]
O80513	4.7e-38	48.48	Cyclin-U4-1 OS=Arabidopsis thaliana OX=3702 GN=CYCU4-1 PE=1 SV=1	[more]
Q0J9W0	3.1e-37	45.90	Cyclin-P1-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP1-1 PE=3 SV=2	[more]
Q75HV0	8.9e-37	39.90	Cyclin-P3-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP3-1 PE=3 SV=1	[more]
Q7XC35	4.9e-35	43.18	Cyclin-P4-1 OS=Oryza sativa subsp. japonica OX=39947 GN=CYCP4-1 PE=2 SV=1	[more]

BLAST of CcUC02G025910 vs. ExPASy TrEMBL


Match Name	E-value	Identity	Description
A0A0A0LQH0	1.1e-114	92.77	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_2G422050 PE=3 SV=1	[more]
A0A5D3BEZ8	8.8e-112	91.06	Cyclin-U1-1 OS=Cucumis melo var. makuwa OX=1194695 GN=E5676_scaffold232G00280 PE...	[more]
A0A1S3C1Y7	8.8e-112	91.06	cyclin-U1-1 OS=Cucumis melo OX=3656 GN=LOC103495936 PE=3 SV=1	[more]
A0A6J1G7K4	3.3e-103	83.69	Cyclin OS=Cucurbita moschata OX=3662 GN=LOC111451542 PE=3 SV=1	[more]
A0A6J1I5U7	9.7e-103	83.26	Cyclin OS=Cucurbita maxima OX=3661 GN=LOC111469864 PE=3 SV=1	[more]

BLAST of CcUC02G025910 vs. TAIR 10


Match Name	E-value	Identity	Description
AT3G21870.1	1.7e-62	56.25	cyclin p2;1	[more]
AT2G44740.1	3.4e-39	48.48	cyclin p4;1	[more]
AT5G61650.1	4.3e-34	39.89	CYCLIN P4;2	[more]
AT3G63120.1	7.3e-34	52.38	cyclin p1;1	[more]
AT3G60550.1	3.6e-33	38.17	cyclin p3;2	[more]

InterPro

Analysis Name: InterPro Annotations of Watermelon (PI 537277) v1
Date Performed: 2022-01-31


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013922	Cyclin PHO80-like	PFAM	PF08613	Cyclin	coord: 27..176 e-value: 4.4E-36 score: 124.7
None	No IPR available	GENE3D	1.10.472.10		coord: 13..223 e-value: 1.4E-53 score: 183.6
None	No IPR available	PANTHER	PTHR15615	UNCHARACTERIZED	coord: 17..204
None	No IPR available	PANTHER	PTHR15615:SF108	PROTEIN CNPPD1	coord: 17..204
IPR013763	Cyclin-like	CDD	cd00043	CYCLIN	coord: 81..169 e-value: 1.04486E-4 score: 37.9885
IPR036915	Cyclin-like superfamily	SUPERFAMILY	47954	Cyclin-like	coord: 83..176

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CcUC02G025910.1	CcUC02G025910.1	mRNA

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
molecular_function	GO:0019901	protein kinase binding