MELO3C017026 (gene) Melon (DHL92) v3.5.1

Overview
NameMELO3C017026
Typegene
OrganismCucumis melo (Melon (DHL92) v3.5.1)
DescriptionNiemann-Pick C1
Locationchr7 : 347389 .. 350184 (+)
Genome Viewer
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATTTTTTATTCACTAGACTATGAAAACGGTGTTATTCAAGCATCTTCTTTCAGAACATACCATACGCCCCTGAATAAGCAGGTGTGGTGTGGTCAGTTTCTAATTGTGATTTAGATAGTTGTATCTAAAGAATATAATTTCTTTTTTTTTTTAATTTTTTCTTTTTTAAATATAAAAAAATTATCAGGTTGACTATATTAATTCGATGAGGGCTGCTCAAGAATTGAGTTCGAGGCTTTCTGATTCTTTGAAGGTAAAATTTTCAACTACAATTTTAGTTTGATTCTCTTTCTTATCATGTTATTTTGAACTAATAATTTTGCTTTTCACTTGGTTTCAACATTTGATTGAGTTCAGTGACGAACTGCTTTTGAACATTATTTCACCTTAATTCTTTCTTTGAACTACTTGCTTCTGTTGCATTAGCTTAATCTTGAACTTATCCTCCTTGTCATTTGCAGATAGAGATCTTTCCCTACTCTGTATTTTACATGTTTTTTGAGCAATACCTCAATATATGGAGGACAGCGTTGATCAACCTTGCCATTGCTATTGGTCAGTAAATAAGGACATTTGTGCGTGCGTTGTTTAATAAATAGTGTAGAAGGCTACCTTGCACTTCCTGTAATACAAATTTGTCCTCCGCGATGATGATATCAAATGCTTTGTGCTTATTTTTCTTTCACTTATTTTTATTTGAAGACCTTTTAAGGAAAATTATCATCCCCAATATAGTTATAAAAGATTTCTTGGTGATACTGAAAAGTTGAAAAGCATTGATTTTATATTCTTTTACTGCTTTCCAGGTGCGGTTTTTATTGTATGCCTGATCATTACATGCAGGTTAGTGATGGTGTTACTGGCATTCAAGTAGACAGATATTTTTCTCTTCTTCAAATGTGCTAACTAAGCTTCCTCGTGCTTGATTTCTTTGTTGTAGCTTATGGACCTCGGCTATCATCTTGTTGGTGTTGGCAATGATTATTGTGGATCTTATGGTATTTTCTTTATACCTAATTATCTCCGGAATGCTATATTAGAAGTTAGTTTAATTATTTTAATATCTATCAGATGTTTATATAAATCTTACCCTTTGCTGACAAGATAATACTTCGCAGGGCGTGATGGCAATTTTGAATATCCAATTGAACGCAATCTCTGTCGTCAATCTTGTCATGTCTGTGGGAATTGCTGTTGAATTTTGTGTGCATTTGACACATGCTTTCTCGGTCAGTACATGATTTCATTTTTCACTAATGCACTCCACTTAAAAGTCAACCGTAGTCATAATCTTTTCATAGGGGGTTTACTTTATGTAATAAAATCCACAACTTAACAATTAATATCATACAGAAATTAGTCGGATTATACAATGTCGCATGATTAATCAGAATGGGCGTTTCAATTAACAGACTGCCTGTCAACGCTTAACATCTTTGGCTAAACTAGTGACTAGAGGCATAATTATCATACCGTTGCCACAAAGGACGGCCTATAATTTTGGGAACTTTTCTCTTCAGAATTGATTATACACTGCTCTCACTAGTCATGCGTTTTCTTATTTATTTATTTTCTCTCACAGGTAAGCAGCGGAGATAGAAATCAACGGATGAAGGAGGCTCTTAGTACAATGGGAGCATCTGTTCTTAGGTACCATTTGCGATGTGTTGTAGTGGAGCTCTGTTTAGATATGCAATCCTGGAAATTTAACCTTGTGTCGTTATTATCATTCTTTATCCAATTTATTTGCCAGTTTTCATTTACTTTATACTGATGCTTGCAGTGGAATCACACTAACAAAGCTAGTCGGGGTCCTTGTACTTTGCTTCTCTAGGACAGAAGTTTTTGTGGTATTAATTTCATCAACCCCCAAATTTAAATTTTAAGTAATCTATTTGCGAGGTCCATTTATATCTTCAATCTATGTTCTGCAGGTCTATTATTTCCATGTGTACTTGGCATTAGTACTTCTTGGATTTTTGCACGGCCTCGTATTCTTGCCGGTAAGTATAGACATGTTTCTTCTGTACAAGAGGTTGTTAGGTGCAAGTTTTGTCTTTTTCACCATGGAGCATACTTATAAAAAGGGAAAAAACTATAATGATTCCCGATAAAAAGGGAAAATGTCCTGGGAAAATGTCCTTGTGTCTCATAGTAGTATTTGTGGGTTGGGTCAGAAAGGGTTGAAATACCTTTTTGACCAAACATGGTTATTTGGGTTATAAAAAATTTCAACCAAAACACTTAACATGTTAAGTAATGAACCCAAGCAGCCAACCAAGAAATTTTTGGGTTTGGTTGGATTGAGTTGGTTCGGGTTATTTGCATGAGTTATACGACAACATTTGCACATGAAAATTTGATATTTCTAATCAAGTTTTTACACCATTCTGGATATTTTTCCTTCTTTGATCTTATGATATTTTCTTATTGTACCTTTGGTGAACTGTGACGGATGGTCATACCAAATTCTTTGTATTCTGCAATGCAATCATCCAATCAAATTTGACATGTATTTATGAAAACATCATGGATCGCTGCAGGTAGTGTTGAGCTTGTTCGGTCCACCTTCAAGATGTGTATTCGTCGAGCAACAGGACAATCGGCCCTCTACTTCGTCTCGGTCATAAAGAGTTATAATTGAATTTGCATCACAGATGAACAGCCAAAGAGGGTTCCGTAGGCCTTTGAAGGTTTGGCGCACTCATTCATTGGCACACATGCTTAAACGCCAATAAAGAAAGGAAGAAAGAATATATATATATATATACACACACACACATATATATATATATA

mRNA sequence

ATTTTTTATTCACTAGACTATGAAAACGGTGTTATTCAAGCATCTTCTTTCAGAACATACCATACGCCCCTGAATAAGCAGGTTGACTATATTAATTCGATGAGGGCTGCTCAAGAATTGAGTTCGAGGCTTTCTGATTCTTTGAAGATAGAGATCTTTCCCTACTCTGTATTTTACATGTTTTTTGAGCAATACCTCAATATATGGAGGACAGCGTTGATCAACCTTGCCATTGCTATTGGTGCGGTTTTTATTGTATGCCTGATCATTACATGCAGCTTATGGACCTCGGCTATCATCTTGTTGGTGTTGGCAATGATTATTGTGGATCTTATGGGCGTGATGGCAATTTTGAATATCCAATTGAACGCAATCTCTGTCGTCAATCTTGTCATGTCTGTGGGAATTGCTGTTGAATTTTGTGTGCATTTGACACATGCTTTCTCGGTAAGCAGCGGAGATAGAAATCAACGGATGAAGGAGGCTCTTAGTACAATGGGAGCATCTGTTCTTAGTGGAATCACACTAACAAAGCTAGTCGGGGTCCTTGTACTTTGCTTCTCTAGGACAGAAGTTTTTGTGGTCTATTATTTCCATGTGTACTTGGCATTAGTACTTCTTGGATTTTTGCACGGCCTCGTATTCTTGCCGGTAGTGTTGAGCTTGTTCGGTCCACCTTCAAGATGTGTATTCGTCGAGCAACAGGACAATCGGCCCTCTACTTCGTCTCGGTCATAAAGAGTTATAATTGAATTTGCATCACAGATGAACAGCCAAAGAGGGTTCCGTAGGCCTTTGAAGGTTTGGCGCACTCATTCATTGGCACACATGCTTAAACGCCAATAAAGAAAGGAAGAAAGAATATATATATATATATACACACACACACATATATATATATATA

Coding sequence (CDS)

ATGAGGGCTGCTCAAGAATTGAGTTCGAGGCTTTCTGATTCTTTGAAGATAGAGATCTTTCCCTACTCTGTATTTTACATGTTTTTTGAGCAATACCTCAATATATGGAGGACAGCGTTGATCAACCTTGCCATTGCTATTGGTGCGGTTTTTATTGTATGCCTGATCATTACATGCAGCTTATGGACCTCGGCTATCATCTTGTTGGTGTTGGCAATGATTATTGTGGATCTTATGGGCGTGATGGCAATTTTGAATATCCAATTGAACGCAATCTCTGTCGTCAATCTTGTCATGTCTGTGGGAATTGCTGTTGAATTTTGTGTGCATTTGACACATGCTTTCTCGGTAAGCAGCGGAGATAGAAATCAACGGATGAAGGAGGCTCTTAGTACAATGGGAGCATCTGTTCTTAGTGGAATCACACTAACAAAGCTAGTCGGGGTCCTTGTACTTTGCTTCTCTAGGACAGAAGTTTTTGTGGTCTATTATTTCCATGTGTACTTGGCATTAGTACTTCTTGGATTTTTGCACGGCCTCGTATTCTTGCCGGTAGTGTTGAGCTTGTTCGGTCCACCTTCAAGATGTGTATTCGTCGAGCAACAGGACAATCGGCCCTCTACTTCGTCTCGGTCATAA

Protein sequence

MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCSLWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGLVFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS*
Homology
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BLAST of MELO3C017026 vs. Swiss-Prot
Match: NPC1_MOUSE (Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2)

HSP 1 Score: 204.1 bits (518), Expect = 1.5e-51
Identity = 97/199 (48.74%), Postives = 151/199 (75.88%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIE-----IFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCL 60
            M+ A+ ++S ++++++ +     +FPYSVFY+F+EQYL I    + NL++++G++F+V L
Sbjct: 1054 MKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTL 1113

Query: 61   IIT-CSLWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHA 120
            ++  C LW++ I+ + +AMI+V++ GVM +  I LNA+S+VNLVMS GI+VEFC H+T A
Sbjct: 1114 VVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRA 1173

Query: 121  FSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVL 180
            F++S+ G R  R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF +YLA+VL
Sbjct: 1174 FTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVL 1233

Query: 181  LGFLHGLVFLPVVLSLFGP 193
            LG  HGL+FLPV+LS  GP
Sbjct: 1234 LGATHGLIFLPVLLSYIGP 1252

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BLAST of MELO3C017026 vs. Swiss-Prot
Match: NPC1_HUMAN (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 202.6 bits (514), Expect = 4.3e-51
Identity = 97/199 (48.74%), Postives = 148/199 (74.37%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIE-----IFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCL 60
            ++ A+ ++S +++++ I      +FPYSVFY+F+EQYL I    + NL +++GA+F+V +
Sbjct: 1055 LKKARLIASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTM 1114

Query: 61   IIT-CSLWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHA 120
            ++  C LW++ I+   +AM++V++ GVM +  I LNA+S+VNLVMS GI+VEFC H+T A
Sbjct: 1115 VLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRA 1174

Query: 121  FSVS-SGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVL 180
            F+VS  G R +R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF +YLA+VL
Sbjct: 1175 FTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVL 1234

Query: 181  LGFLHGLVFLPVVLSLFGP 193
            LG  HGL+FLPV+LS  GP
Sbjct: 1235 LGATHGLIFLPVLLSYIGP 1253

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BLAST of MELO3C017026 vs. Swiss-Prot
Match: NPC1_PIG (Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1)

HSP 1 Score: 201.8 bits (512), Expect = 7.3e-51
Identity = 97/199 (48.74%), Postives = 148/199 (74.37%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIE-----IFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCL 60
            M+ A+ ++S ++ ++ +E     +FPYSVFY+F+EQYL +    + NL +++GA+F+V +
Sbjct: 1054 MQKARLIASNITRTMGLEASSYRVFPYSVFYVFYEQYLTVIDDTIFNLGVSLGAIFLVTV 1113

Query: 61   IIT-CSLWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHA 120
            ++  C LW + I+ + +AMI+V++ GVM +  I LNA+S+VNLVMS GI+VEFC H+T A
Sbjct: 1114 VLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRA 1173

Query: 121  FSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVL 180
            F++S+ G R  R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF +YLA+VL
Sbjct: 1174 FTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAIVL 1233

Query: 181  LGFLHGLVFLPVVLSLFGP 193
            LG  HGL+FLPV+LS  GP
Sbjct: 1234 LGATHGLIFLPVLLSYIGP 1252

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BLAST of MELO3C017026 vs. Swiss-Prot
Match: NPC1_YEAST (Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCR1 PE=1 SV=1)

HSP 1 Score: 159.1 bits (401), Expect = 5.5e-38
Identity = 81/190 (42.63%), Postives = 127/190 (66.84%), Query Frame = 1 

Query: 10   RLSDSL-KIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCSLWTSAIIL 69
            R+S S  ++++F YS FY+FF QY  +    L  +  AI  +F +  +   ++ +S ++ 
Sbjct: 971  RISSSFPELDMFAYSPFYIFFVQYQTLGPLTLKLIGSAIILIFFISSVFLQNIRSSFLLA 1030

Query: 70   LVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSV----SSGDRNQ 129
            LV+ MIIVD+  +MA+L I LNA+S+VNL++ VG+ VEFCVH+  +F+V    +  D N 
Sbjct: 1031 LVVTMIIVDIGALMALLGISLNAVSLVNLIICVGLGVEFCVHIVRSFTVVPSETKKDANS 1090

Query: 130  RMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGLVFLP 189
            R+  +L+T+G SV+ GITLTK +GV VL F+++++F V+YF ++  L+++  LH L+FLP
Sbjct: 1091 RVLYSLNTIGESVIKGITLTKFIGVCVLAFAQSKIFDVFYFRMWFTLIIVAALHALLFLP 1150

Query: 190  VVLSLFGPPS 195
             +LSLFG  S
Sbjct: 1151 ALLSLFGGES 1160

[Close]
BLAST of MELO3C017026 vs. Swiss-Prot
Match: NPCL1_HUMAN (Niemann-Pick C1-like protein 1 OS=Homo sapiens GN=NPC1L1 PE=1 SV=2)

HSP 1 Score: 153.3 bits (386), Expect = 3.0e-36
Identity = 80/202 (39.60%), Postives = 130/202 (64.36%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLK--------IEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFI 60
            +RAA+EL++ ++  L+         E+FPY++  +F+EQYL I    L  L++ +   F 
Sbjct: 1093 LRAARELAANITADLRKVPGTDPAFEVFPYTITNVFYEQYLTILPEGLFMLSLCLVPTFA 1152

Query: 61   V-CLIITCSLWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHL 120
            V CL++   L +  + LL + MI+VD +G MA+  I  NA+S++NLV +VG++VEF  H+
Sbjct: 1153 VSCLLLGLDLRSGLLNLLSIVMILVDTVGFMALWGISYNAVSLINLVSAVGMSVEFVSHI 1212

Query: 121  THAFSVSSGDR-NQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLA 180
            T +F++S+     +R KEA  +MG++V +G+ +T L G+LVL  ++ ++  +++F + L 
Sbjct: 1213 TRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLAKAQLIQIFFFRLNLL 1272

Query: 181  LVLLGFLHGLVFLPVVLSLFGP 193
            + LLG LHGLVFLPV+LS  GP
Sbjct: 1273 ITLLGLLHGLVFLPVILSYVGP 1294

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BLAST of MELO3C017026 vs. TrEMBL
Match: A0A0A0L4L2_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_4G658620 PE=4 SV=1)

HSP 1 Score: 406.8 bits (1044), Expect = 1.7e-110
Identity = 211/212 (99.53%), Postives = 212/212 (100.00%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 1082 MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 1141

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG
Sbjct: 1142 LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 1201

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL
Sbjct: 1202 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 1261

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 213
            VFLPVVLSLFGPPSRCVFVEQQDNRPSTSS+S
Sbjct: 1262 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSQS 1293

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BLAST of MELO3C017026 vs. TrEMBL
Match: A0A068UFF5_COFCA (Uncharacterized protein OS=Coffea canephora GN=GSCOC_T00024510001 PE=4 SV=1)

HSP 1 Score: 374.8 bits (961), Expect = 7.0e-101
Identity = 187/211 (88.63%), Postives = 205/211 (97.16%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAA++ SSR+SDSLKIEIFPY+VFYMFFEQYLNIWRTA+INL IAIGAVFIVCL+ITCS
Sbjct: 1084 MRAARDFSSRVSDSLKIEIFPYAVFYMFFEQYLNIWRTAIINLVIAIGAVFIVCLVITCS 1143

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMI+VDLMGVMAILNIQLNA+SVVNLVMSVGIAVEFCVH+THAF VSSG
Sbjct: 1144 LWTSAIILLVLAMIVVDLMGVMAILNIQLNAVSVVNLVMSVGIAVEFCVHITHAFLVSSG 1203

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMK+AL+TMGASV SGITLTKLVGVLVLCFSRTEVFVVYYF +YLALVLLGFLHGL
Sbjct: 1204 DRNQRMKDALTTMGASVFSGITLTKLVGVLVLCFSRTEVFVVYYFKMYLALVLLGFLHGL 1263

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSR 212
            VFLPV+LSLFGPPSRCV +E+Q++RPSTSS+
Sbjct: 1264 VFLPVLLSLFGPPSRCVLIEKQEDRPSTSSQ 1294

[Close]
BLAST of MELO3C017026 vs. TrEMBL
Match: M1AM77_SOLTU (Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400009984 PE=4 SV=1)

HSP 1 Score: 369.8 bits (948), Expect = 2.3e-99
Identity = 183/211 (86.73%), Postives = 204/211 (96.68%), Query Frame = 1 

Query: 1   MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
           MRAA+E SSR+SDSLK+E+FPY+VFYMFFEQYL+IWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 122 MRAAREFSSRVSDSLKMEVFPYAVFYMFFEQYLSIWRTALINLAIAIGAVFIVCLIITCS 181

Query: 61  LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            WTSAIILLVL MI++DLMGVMAILNIQLNA+SVVNLVM+VGIAVEFCVH+THAF VSSG
Sbjct: 182 FWTSAIILLVLTMIVLDLMGVMAILNIQLNAVSVVNLVMAVGIAVEFCVHITHAFLVSSG 241

Query: 121 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
           DRNQRMKEAL+TMGASV SGITLTKLVGV+VLCFSRTEVFVVYYF +YLALVLLGFLHGL
Sbjct: 242 DRNQRMKEALTTMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGL 301

Query: 181 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSR 212
           +FLPV+LS+FGPPSRCV VE+Q++RPSTSS+
Sbjct: 302 IFLPVLLSIFGPPSRCVLVEKQEDRPSTSSQ 332

[Close]
BLAST of MELO3C017026 vs. TrEMBL
Match: M1AM78_SOLTU (Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400009984 PE=4 SV=1)

HSP 1 Score: 369.8 bits (948), Expect = 2.3e-99
Identity = 183/211 (86.73%), Postives = 204/211 (96.68%), Query Frame = 1 

Query: 1   MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
           MRAA+E SSR+SDSLK+E+FPY+VFYMFFEQYL+IWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 373 MRAAREFSSRVSDSLKMEVFPYAVFYMFFEQYLSIWRTALINLAIAIGAVFIVCLIITCS 432

Query: 61  LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            WTSAIILLVL MI++DLMGVMAILNIQLNA+SVVNLVM+VGIAVEFCVH+THAF VSSG
Sbjct: 433 FWTSAIILLVLTMIVLDLMGVMAILNIQLNAVSVVNLVMAVGIAVEFCVHITHAFLVSSG 492

Query: 121 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
           DRNQRMKEAL+TMGASV SGITLTKLVGV+VLCFSRTEVFVVYYF +YLALVLLGFLHGL
Sbjct: 493 DRNQRMKEALTTMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGL 552

Query: 181 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSR 212
           +FLPV+LS+FGPPSRCV VE+Q++RPSTSS+
Sbjct: 553 IFLPVLLSIFGPPSRCVLVEKQEDRPSTSSQ 583

[Close]
BLAST of MELO3C017026 vs. TrEMBL
Match: K4BVX6_SOLLC (Uncharacterized protein OS=Solanum lycopersicum PE=4 SV=1)

HSP 1 Score: 367.1 bits (941), Expect = 1.5e-98
Identity = 181/211 (85.78%), Postives = 203/211 (96.21%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAA+E SSR+SDSLK+E+FPY+VFYMFFEQYL+IWRTALINLAIAIGAVFIVCL+ITCS
Sbjct: 1083 MRAAREFSSRVSDSLKMEVFPYAVFYMFFEQYLSIWRTALINLAIAIGAVFIVCLVITCS 1142

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
             WTSAIILLVL MI++DLMGVMAIL IQLNA+SVVNLVM+VGIAVEFCVH+THAF VSSG
Sbjct: 1143 FWTSAIILLVLTMIVLDLMGVMAILKIQLNAVSVVNLVMAVGIAVEFCVHITHAFLVSSG 1202

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEAL+TMGASV SGITLTKLVGV+VLCFSRTEVFVVYYF +YLALVLLGFLHGL
Sbjct: 1203 DRNQRMKEALTTMGASVFSGITLTKLVGVIVLCFSRTEVFVVYYFQMYLALVLLGFLHGL 1262

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSR 212
            +FLPV+LS+FGPPSRCV VE+Q++RPSTSS+
Sbjct: 1263 IFLPVLLSIFGPPSRCVLVEKQEDRPSTSSQ 1293

[Close]
BLAST of MELO3C017026 vs. TAIR10
Match: AT4G38350.2 (AT4G38350.2 Patched family protein)

HSP 1 Score: 312.0 bits (798), Expect = 2.8e-85
Identity = 153/210 (72.86%), Postives = 182/210 (86.67%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            +RAA+E SSR+S+SLKI+IFPYSVFY+FFEQYLNIW  AL NLAIAIGA+FIVC +IT S
Sbjct: 1085 LRAAREFSSRISNSLKIDIFPYSVFYIFFEQYLNIWTVALTNLAIAIGAIFIVCWLITSS 1144

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
             W+SAII+LVL MI+VDLMG+M IL IQLNA+SVVNL+MS+GIAVEFCVH++HAF +SSG
Sbjct: 1145 AWSSAIIVLVLVMILVDLMGMMVILGIQLNAVSVVNLIMSIGIAVEFCVHISHAFLMSSG 1204

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DR  R +EAL TMGASV SGITLTKLVGV+VLCF+R+E+FVVYYF +YLALV++GFLHGL
Sbjct: 1205 DREHRAREALETMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQMYLALVIIGFLHGL 1264

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSS 211
            VFLPV+LSL GPP   + +EQQ    ++SS
Sbjct: 1265 VFLPVILSLAGPPQLNLDIEQQQTDEASSS 1294

[Close]
BLAST of MELO3C017026 vs. TAIR10
Match: AT1G42470.1 (AT1G42470.1 Patched family protein)

HSP 1 Score: 194.9 bits (494), Expect = 5.1e-50
Identity = 93/116 (80.17%), Postives = 109/116 (93.97%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQE S+++S SLK+EI+PYSVFYMFFEQYL+IW+TALINL+IAI AVF+VCLIITCS
Sbjct: 1050 MRAAQEFSAKVSRSLKMEIYPYSVFYMFFEQYLDIWKTALINLSIAIAAVFVVCLIITCS 1109

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFS 117
             W+SAIILLV+AMII+DL+GVMA+ +IQLNA+SVVNL+MSVGIAVEFCVH+THAFS
Sbjct: 1110 FWSSAIILLVIAMIIIDLLGVMAVFHIQLNALSVVNLIMSVGIAVEFCVHITHAFS 1165

[Close]
BLAST of MELO3C017026 vs. NCBI nr
Match: gi|659104696|ref|XP_008452964.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis melo])

HSP 1 Score: 408.3 bits (1048), Expect = 8.3e-111
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 1082 MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 1141

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG
Sbjct: 1142 LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 1201

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL
Sbjct: 1202 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 1261

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 213
            VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS
Sbjct: 1262 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 1293

[Close]
BLAST of MELO3C017026 vs. NCBI nr
Match: gi|659104698|ref|XP_008452965.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Cucumis melo])

HSP 1 Score: 408.3 bits (1048), Expect = 8.3e-111
Identity = 212/212 (100.00%), Postives = 212/212 (100.00%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 975  MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 1034

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG
Sbjct: 1035 LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 1094

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL
Sbjct: 1095 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 1154

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 213
            VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS
Sbjct: 1155 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 1186

[Close]
BLAST of MELO3C017026 vs. NCBI nr
Match: gi|778697176|ref|XP_011654272.1| (PREDICTED: Niemann-Pick C1 protein isoform X2 [Cucumis sativus])

HSP 1 Score: 406.8 bits (1044), Expect = 2.4e-110
Identity = 211/212 (99.53%), Postives = 212/212 (100.00%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 975  MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 1034

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG
Sbjct: 1035 LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 1094

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL
Sbjct: 1095 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 1154

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 213
            VFLPVVLSLFGPPSRCVFVEQQDNRPSTSS+S
Sbjct: 1155 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSQS 1186

[Close]
BLAST of MELO3C017026 vs. NCBI nr
Match: gi|778697173|ref|XP_011654271.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis sativus])

HSP 1 Score: 406.8 bits (1044), Expect = 2.4e-110
Identity = 211/212 (99.53%), Postives = 212/212 (100.00%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS
Sbjct: 1082 MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 1141

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG
Sbjct: 1142 LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 1201

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL
Sbjct: 1202 DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 1261

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSRS 213
            VFLPVVLSLFGPPSRCVFVEQQDNRPSTSS+S
Sbjct: 1262 VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSQS 1293

[Close]
BLAST of MELO3C017026 vs. NCBI nr
Match: gi|661888842|emb|CDP07285.1| (unnamed protein product [Coffea canephora])

HSP 1 Score: 374.8 bits (961), Expect = 1.0e-100
Identity = 187/211 (88.63%), Postives = 205/211 (97.16%), Query Frame = 1 

Query: 1    MRAAQELSSRLSDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIGAVFIVCLIITCS 60
            MRAA++ SSR+SDSLKIEIFPY+VFYMFFEQYLNIWRTA+INL IAIGAVFIVCL+ITCS
Sbjct: 1084 MRAARDFSSRVSDSLKIEIFPYAVFYMFFEQYLNIWRTAIINLVIAIGAVFIVCLVITCS 1143

Query: 61   LWTSAIILLVLAMIIVDLMGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSG 120
            LWTSAIILLVLAMI+VDLMGVMAILNIQLNA+SVVNLVMSVGIAVEFCVH+THAF VSSG
Sbjct: 1144 LWTSAIILLVLAMIVVDLMGVMAILNIQLNAVSVVNLVMSVGIAVEFCVHITHAFLVSSG 1203

Query: 121  DRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFHVYLALVLLGFLHGL 180
            DRNQRMK+AL+TMGASV SGITLTKLVGVLVLCFSRTEVFVVYYF +YLALVLLGFLHGL
Sbjct: 1204 DRNQRMKDALTTMGASVFSGITLTKLVGVLVLCFSRTEVFVVYYFKMYLALVLLGFLHGL 1263

Query: 181  VFLPVVLSLFGPPSRCVFVEQQDNRPSTSSR 212
            VFLPV+LSLFGPPSRCV +E+Q++RPSTSS+
Sbjct: 1264 VFLPVLLSLFGPPSRCVLIEKQEDRPSTSSQ 1294

The following BLAST results are available for this feature:
BLAST of MELO3C017026 vs. Swiss-Prot
Match NameE-valueIdentityDescription
NPC1_MOUSE1.5e-5148.74Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2[more]
NPC1_HUMAN4.3e-5148.74Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2[more]
NPC1_PIG7.3e-5148.74Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1[more]
NPC1_YEAST5.5e-3842.63Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 2... [more]
NPCL1_HUMAN3.0e-3639.60Niemann-Pick C1-like protein 1 OS=Homo sapiens GN=NPC1L1 PE=1 SV=2[more]
BLAST of MELO3C017026 vs. TrEMBL
Match NameE-valueIdentityDescription
A0A0A0L4L2_CUCSA1.7e-11099.53Uncharacterized protein OS=Cucumis sativus GN=Csa_4G658620 PE=4 SV=1[more]
A0A068UFF5_COFCA7.0e-10188.63Uncharacterized protein OS=Coffea canephora GN=GSCOC_T00024510001 PE=4 SV=1[more]
M1AM77_SOLTU2.3e-9986.73Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400009984 PE=4 SV=1[more]
M1AM78_SOLTU2.3e-9986.73Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400009984 PE=4 SV=1[more]
K4BVX6_SOLLC1.5e-9885.78Uncharacterized protein OS=Solanum lycopersicum PE=4 SV=1[more]
BLAST of MELO3C017026 vs. TAIR10
Match NameE-valueIdentityDescription
AT4G38350.22.8e-8572.86 Patched family protein[more]
AT1G42470.15.1e-5080.17 Patched family protein[more]
BLAST of MELO3C017026 vs. NCBI nr
Match NameE-valueIdentityDescription
gi|659104696|ref|XP_008452964.1|8.3e-111100.00PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis melo][more]
gi|659104698|ref|XP_008452965.1|8.3e-111100.00PREDICTED: Niemann-Pick C1 protein isoform X2 [Cucumis melo][more]
gi|778697176|ref|XP_011654272.1|2.4e-11099.53PREDICTED: Niemann-Pick C1 protein isoform X2 [Cucumis sativus][more]
gi|778697173|ref|XP_011654271.1|2.4e-11099.53PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis sativus][more]
gi|661888842|emb|CDP07285.1|1.0e-10088.63unnamed protein product [Coffea canephora][more]
Annotated Terms
The following terms have been associated with this gene:
Vocabulary: INTERPRO
TermDefinition
IPR003392Ptc/Disp
IPR003392Ptc/Disp
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0030301 cholesterol transport
biological_process GO:0007165 signal transduction
biological_process GO:0006869 lipid transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0005886 plasma membrane
cellular_component GO:0009506 plasmodesma
molecular_function GO:0008158 hedgehog receptor activity
molecular_function GO:0005319 lipid transporter activity
Unigene
This gene is associated with the following unigenes:
Unigene NameAnalysis NameSequence type in Unigene
MU63462melon EST collection version 4.0transcribed_cluster
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
MELO3C017026T1MELO3C017026T1mRNA
MELO3C017026T3MELO3C017026T3mRNA
MELO3C017026T2MELO3C017026T2mRNA


The following transcribed_cluster feature(s) are associated with this gene:

Feature NameUnique NameType
MU63462MU63462transcribed_cluster


InterPro
Analysis Name: InterPro Annotations of melon
Date Performed: 2016-09-28
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR003392Protein patched/dispatchedPFAMPF02460Patchedcoord: 4..109
score: 2.9
NoneNo IPR availableGENE3DG3DSA:1.20.1640.10coord: 1..112
score: 1.4
NoneNo IPR availablePANTHERPTHR10796PATCHED-RELATEDcoord: 1..130
score: 2.7
NoneNo IPR availablePANTHERPTHR10796:SF117PATCHED FAMILY PROTEINcoord: 1..130
score: 2.7
NoneNo IPR availableunknownSSF82866Multidrug efflux transporter AcrB transmembrane domaincoord: 1..110
score: 1.44