MELO3C026868.2 (gene) Melon (DHL92) v3.6.1 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	MELO3C026868.2
Type	gene
Organism	Cucumis melo (Melon (DHL92) v3.6.1)
Description	Cysteine proteinase inhibitor
Location	chr08 : 15916208 .. 15916950 (+)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRCDSthree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

TTTAAATCTTAATTCAATTGAACATCATGAATATGATAGGGAAAAAAAAAGCAAAAACTTCACAGACCGAAAATTAAAATAAAAAATGAAATAGTTTACCAAACAAGCTTTTTAAGTAACACTACCAAACTTTTGGGTGATCAAAGCGAATCAAATTCCCTTCTACCATATCCACTTCTTGGATGGAACCACACCCTCTATAAATGTTGAACACTTCCATTTATGTCGACAAAACCATTGTTGTCAACTTTCAATTTCTCAAGCTTCAAACGATTGCCAAACAAAACTTAAAATGAGTAATATGTTAGTGTCTCCTCAAGAAGCTAATTTGTTGGTTCAAAATCACAAAAATAGTGAATGGAAAGCAATAGAAGACACAAAGGACCCTTACATTGAAGACATGGGACGGTTTTCGGTGGCAAAGTTTACAAGAAATCAAGACATCGAAGAAATGGCGACGTTCATTCGAGTGGTGAGCAGTGAGTATCTAGTGGTGAATGAAGGAACTATGTATCGAATTGTGGTAGAGATTAGGAAAGAGAATGTAAGTCAATCACGTGAGTTATATGTGGCTAAGGTATTAGATCATAAGCATCCTTTCAATTCTTGGACACTCTTATCTTTTGAATGCTCTACCCTTTTAGCTTTGCCTTCAAGCTTGGCTCTTTAGGGAATCCTCCCATTTGGTTCATTATCTCTATCCTTTTTAATATGCGTCAATAAAATAACAGACTTTTATGTCT

mRNA sequence

TTTAAATCTTAATTCAATTGAACATCATGAATATGATAGGGAAAAAAAAAGCAAAAACTTCACAGACCGAAAATTAAAATAAAAAATGAAATAGTTTACCAAACAAGCTTTTTAAGTAACACTACCAAACTTTTGGGTGATCAAAGCGAATCAAATTCCCTTCTACCATATCCACTTCTTGGATGGAACCACACCCTCTATAAATGTTGAACACTTCCATTTATGTCGACAAAACCATTGTTGTCAACTTTCAATTTCTCAAGCTTCAAACGATTGCCAAACAAAACTTAAAATGAGTAATATGTTAGTGTCTCCTCAAGAAGCTAATTTGTTGGTTCAAAATCACAAAAATAGTGAATGGAAAGCAATAGAAGACACAAAGGACCCTTACATTGAAGACATGGGACGGTTTTCGGTGGCAAAGTTTACAAGAAATCAAGACATCGAAGAAATGGCGACGTTCATTCGAGTGGTGAGCAGTGAGTATCTAGTGGTGAATGAAGGAACTATGTATCGAATTGTGGTAGAGATTAGGAAAGAGAATGTAAGTCAATCACGTGAGTTATATGTGGCTAAGGTATTAGATCATAAGCATCCTTTCAATTCTTGGACACTCTTATCTTTTGAATGCTCTACCCTTTTAGCTTTGCCTTCAAGCTTGGCTCTTTAGGGAATCCTCCCATTTGGTTCATTATCTCTATCCTTTTTAATATGCGTCAATAAAATAACAGACTTTTATGTCT

Coding sequence (CDS)

ATGAGTAATATGTTAGTGTCTCCTCAAGAAGCTAATTTGTTGGTTCAAAATCACAAAAATAGTGAATGGAAAGCAATAGAAGACACAAAGGACCCTTACATTGAAGACATGGGACGGTTTTCGGTGGCAAAGTTTACAAGAAATCAAGACATCGAAGAAATGGCGACGTTCATTCGAGTGGTGAGCAGTGAGTATCTAGTGGTGAATGAAGGAACTATGTATCGAATTGTGGTAGAGATTAGGAAAGAGAATGTAAGTCAATCACGTGAGTTATATGTGGCTAAGGTATTAGATCATAAGCATCCTTTCAATTCTTGGACACTCTTATCTTTTGAATGCTCTACCCTTTTAGCTTTGCCTTCAAGCTTGGCTCTTTAG

Protein sequence

MSNMLVSPQEANLLVQNHKNSEWKAIEDTKDPYIEDMGRFSVAKFTRNQDIEEMATFIRVVSSEYLVVNEGTMYRIVVEIRKENVSQSRELYVAKVLDHKHPFNSWTLLSFECSTLLALPSSLAL

Homology

[Close]

BLAST of MELO3C026868.2 vs. NCBI nr
Match: XP_022132703.1 (cysteine proteinase inhibitor 5-like [Momordica charantia])

HSP 1 Score: 63.2 bits (152), Expect = 7.4e-07
Identity = 43/118 (36.44%), Postives = 65/118 (55.08%), Query Frame = 0


Query: 1   MSNMLVSPQEANLLVQNHKNSEWKAIEDTKDPYIEDMGRFSVAKFTRNQDIEEMATFIRV 60
           M ++ V+P + + L    K   W+ I++ KDPY+++MGRF+V +  +   +     F+ V
Sbjct: 32  MDSVAVAPAQNDALQHVKKPGGWEPIKNIKDPYVQEMGRFAVMEQPKPVGLVASMEFVGV 91

Query: 61  VSSEYLVVNEGTMYRIVVEIR-KENV------SQSRELYVAKVLDHKHPFNSWTLLSF 112
           VS E  +V  G  YR+VVE++  E +        S  LYVA VLD K    SW +LSF
Sbjct: 92  VSGEIQLVAAGKEYRLVVEVKVTEKIIVHGCPVSSIRLYVAVVLD-KPSDKSWKVLSF 148

[Close]

BLAST of MELO3C026868.2 vs. NCBI nr
Match: XP_022132702.1 (cysteine proteinase inhibitor 5-like [Momordica charantia])

HSP 1 Score: 61.6 bits (148), Expect = 2.2e-06
Identity = 44/119 (36.97%), Postives = 66/119 (55.46%), Query Frame = 0


Query: 1   MSNMLVSPQEANLLVQNHKNSEWKAIEDTKDPYIEDMGRFSV-AKFTRNQDIEEMATFIR 60
           M ++ V+P + + L+       W+ I++ KDPY+++MGRF+V  +  +  ++     FI 
Sbjct: 1   MDSVAVAPAQNDALLHLKMPGGWEPIKNIKDPYVQEMGRFAVMEQHPKPSELIASMEFIG 60

Query: 61  VVSSEYLVVNEGTMYRIVVEIR-KENV------SQSRELYVAKVLDHKHPFNSWTLLSF 112
           VVS E  +V  G  YR+VVE+R  E +        S  LYVA VLD K    SW +LSF
Sbjct: 61  VVSGEIQLVAHGKEYRLVVEVRVTEKIIVHGCPVSSIRLYVAVVLD-KPSDKSWKVLSF 118

[Close]

BLAST of MELO3C026868.2 vs. NCBI nr
Match: XP_023543511.1 (cysteine proteinase inhibitor 5-like [Cucurbita pepo subsp. pepo])

HSP 1 Score: 58.5 bits (140), Expect = 1.8e-05
Identity = 41/116 (35.34%), Postives = 68/116 (58.62%), Query Frame = 0


Query: 1   MSNMLVSPQEANLLVQNHKNSEWKAIEDTKDPYIEDMGRFSVAKFTRNQDIEEMATFIRV 60
           M   +V+  + + L+   K+ +W+ + +  DPY++++GRF+V +         M TF+RV
Sbjct: 1   MDLKVVAHGQNDALLHKPKSCDWEPV-NVHDPYVQELGRFAVMEHVHGLCGVGM-TFVRV 60

Query: 61  VSSEYLVVNEGTMYRIVVEIRKENVSQSR----ELYVAKVLDHKHPFNSWTLLSFE 113
           VS E  +V EG  Y +VVE+++  V   +    +LYVA+VLD K    SW LL+F+
Sbjct: 61  VSGESKMVCEGKKYSLVVEVKEVLVLPHQCPAIKLYVAEVLD-KQCAKSWELLAFK 113

[Close]

BLAST of MELO3C026868.2 vs. NCBI nr
Match: XP_022936218.1 (cysteine proteinase inhibitor 8-like [Cucurbita moschata])

HSP 1 Score: 54.7 bits (130), Expect = 2.6e-04
Identity = 44/113 (38.94%), Postives = 61/113 (53.98%), Query Frame = 0


Query: 2   SNMLVSPQEANLLVQNHKNSE---WKAIEDTKDPYIEDMGRFSVAKFTRNQDIEEMATFI 61
           S++  +P +   + Q+ K  E   WK IED KDPY+++MGRF+V +   N  I E   FI
Sbjct: 3   SHVEAAPGQNEAMFQDKKGIEVGQWKPIEDIKDPYVQEMGRFAVMEHD-NMRIGENLKFI 62

Query: 62  RVVSSEYLVVNEGTMYRIVVEIRKENVSQSRELYVAKVLDHKHPFNSWTLLSF 112
            V S E  VV EG  YR++  I+  N      LY+A V D K    +W L+ F
Sbjct: 63  CVQSGEKQVV-EGMNYRLL--IKASNHLGISSLYMAIVYD-KPWEKTWKLIEF 110

The following BLAST results are available for this feature:

BLAST of MELO3C026868.2 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_022132703.1	7.4e-07	36.44	cysteine proteinase inhibitor 5-like [Momordica charantia]	[more]
XP_022132702.1	2.2e-06	36.97	cysteine proteinase inhibitor 5-like [Momordica charantia]	[more]
XP_023543511.1	1.8e-05	35.34	cysteine proteinase inhibitor 5-like [Cucurbita pepo subsp. pepo]	[more]
XP_022936218.1	2.6e-04	38.94	cysteine proteinase inhibitor 8-like [Cucurbita moschata]	[more]

BLAST of MELO3C026868.2 vs. TAIR10


Match Name	E-value	Identity	Description

BLAST of MELO3C026868.2 vs. Swiss-Prot


Match Name	E-value	Identity	Description

BLAST of MELO3C026868.2 vs. TrEMBL


Match Name	E-value	Identity	Description

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **Molecular Function**
Term	Definition
GO:0004869	cysteine-type endopeptidase inhibitor activity

Vocabulary: **INTERPRO**
Term	Definition
IPR027214	Cystatin

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0010951	negative regulation of endopeptidase activity
biological_process	GO:0010466	negative regulation of peptidase activity
biological_process	GO:0008152	metabolic process
biological_process	GO:0008150	biological_process
cellular_component	GO:0005575	cellular_component
molecular_function	GO:0004869	cysteine-type endopeptidase inhibitor activity
molecular_function	GO:0030414	peptidase inhibitor activity
molecular_function	GO:0003824	catalytic activity
molecular_function	GO:0005515	protein binding
molecular_function	GO:0008270	zinc ion binding
molecular_function	GO:0003674	molecular_function

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MELO3C026868.2.1	MELO3C026868.2.1	mRNA

InterPro

Analysis Name: InterPro Annotations of melon v3.6.1
Date Performed: 2018-09-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.10.450.10		coord: 20..116 e-value: 7.6E-14 score: 53.5
None	No IPR available	SUPERFAMILY	SSF54403	Cystatin/monellin	coord: 20..113
IPR027214	Cystatin	PANTHER	PTHR11413	CYSTATIN FAMILY MEMBER	coord: 22..113

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
MELO3C026868.2	CmoCh03G000830	Cucurbita moschata (Rifu)	cmomedB699
MELO3C026868.2	Lsi01G019050	Bottle gourd (USVL1VR-Ls)	lsimedB166
MELO3C026868.2	Cp4.1LG10g11840	Cucurbita pepo (Zucchini)	cpemedB085
MELO3C026868.2	ClCG04G000400	Watermelon (Charleston Gray)	medwcgB530
MELO3C026868.2	Cla97C04G068780	Watermelon (97103) v2	medwmbB535
MELO3C026868.2	Bhi03G002119	Wax gourd	medwgoB649

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
MELO3C026868.2	Cucurbita maxima (Rimu)	cmamedB911
MELO3C026868.2	Cucurbita moschata (Rifu)	cmomedB899
MELO3C026868.2	Cucurbita pepo (Zucchini)	cpemedB536