MELO3C025010 (gene) Melon (DHL92) v3.5.1 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	MELO3C025010
Type	gene
Organism	Cucumis melo (Melon (DHL92) v3.5.1)
Description	MLH1
Location	chr3 : 17041506 .. 17043437 (-)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGCAGATGATGTATTCGCACTGCTTCAGCATGGAACTCATCTCTATCTAGCGAATGTTGTGAATCTGAGGTAAAAACTCCTTGGGCAAATAATGAGTTTAGTTTGAATTTATTGTGCAATATTTTTTTATGAAGTTGCAGAAACTTCTTCAACTATATGGTACTTTTGGCGTAGTCTTGCTCTATCTGGCCGTTGGATTTTGCAACCATTTGTGACATGTCATATTCCCAAATTCCCAATATTAGCATACTGTTGAAATAACTTATTTGGATGTCTCTTTGAATCACCTATATGTGGTAAGCTACTATCAACCCAATTTTCAAATATTCAAATAGACTGAAATGAGGAGCTATGAGAAGAGTGAAAGCCTATTGGGTACAAGTGGAATATAATGAGTTGAAGAATTCTAATTTTGGATACAGTTAAACATCTGTTAAAAAAGAAAAGAAAAGAAAAGAAAATGGATCATAAACCTCCGTGTAAAATGTATTCTCTTATTTCACTTAGAAAGAAAGGGGTTTTGTTAAATAGAAGAAATACCCAATACAAAGTAGGATAATACAAAATAAGGAAAAGATAGATACACAAATATATCTTTAAATACAATGAAAATATCAACAATAAAGGAAAGAATTAACAAAGGAAATAATCAACAAACACAATGGGATAAGATATAGAAACTGGCCATTGTATCTCCATGTATGTACACGGTGCTGATAGGAATCAAAATAAAGAGAAGCTTTTATTTATTTCACACTTTTGTATAACAGATGTACAGTACCCTTCCTCCCACTCTCAAGACAATCAAGACACTACAAAATATTAAGCACCCTACACCACAACTTATTACACATATACATAACTTCTACCCAATAACCCAGACAACTTTAGATAACTTACGAGCCCTCCTAACTCCTCCTAACCCGTAAGCATCCTTATCCATACTACTATTACATGACTCCCCTTCTTCATAAATACTGACATTCCCCTTTTTATCATTACGATATTATTGAAATATAATTAGAGGACTATTAGGTGCCTGACGTTTGATAGGTTTGATACACTTGTTTTATGACATATCCTTTTGCTTTCTTGCTCCATCCATTGTATTTTGTAGCAAAGAACTCATGTATCAGCAAGTTTTGCGTCGATTTGCTCATTTTAATGCAATACAATTAAGCAACCCAGCCCCTCTATTCGAGTTACTTATTTTGGCACTGAAGGAGGAATATGCAAATTCAGAGTGTGAGAATGATGATTTTAATGAGAAGGTAGCTGAGGTAACGTGGTGGCATCTGATATATCTTTTTAAGGCATAAAATAGTGCTTTCCTCGGTTATAGCTTCTTGTTTTACATAGCTAATACTGTCGCTGTTTCTTAGACGAGTACAAAACTGCTCAAGTTGAAAGCTGAAATGCTGGAGGAATTTTTCTGCATAAGTATTGACAGAAATGGGAATTTGGCTAGTCTTCCAGTCGTACTTGACCAATACACACCTGATATGGACCGTGTTCCTGAGTTTATGCTTTCTTTAGCTAATGATGTAAGTTCTTATGTGCTCAACTTTTTGTCATTCCATAAATTTATTTTTTCATTATCCATTTGGTCATGGTTTCATCTATTCATTTGTTTATGATGCTTGGTATTTGTTGAGTATTAATTTGGGCATAAAATTGGTTAAATAATTTACTAATTTTCTATTGTGGATTGGTCGTTTAGTACGAACTTATACTTCAAAATTTCCCCTCAACACAAGCGAAATTACATGTTTACACTGTAAGAACCCAAAAGCAGATTAATTCTCCTATTGGTGATGGTCTTGTACCCATTAGTAGGTTTCTTATTCATATAGAACATTTAGTAATGGAATTTAATGCTGCTGCTTTGCATAGCAAGGACAAAAGTTTCAAAGTTGGAGGCTTGGCTTGA

mRNA sequence

ATGGCAGATGATGTATTCGCACTGCTTCAGCATGGAACTCATCTCTATCTAGCGAATGTTGTGAATCTGAGCAAAGAACTCATGTATCAGCAAGTTTTGCGTCGATTTGCTCATTTTAATGCAATACAATTAAGCAACCCAGCCCCTCTATTCGAGTTACTTATTTTGGCACTGAAGGAGGAATATGCAAATTCAGAGTGTGAGAATGATGATTTTAATGAGAAGGTAGCTGAGACGAGTACAAAACTGCTCAAGTTGAAAGCTGAAATGCTGGAGGAATTTTTCTGCATAAGTATTGACAGAAATGGGAATTTGGCTAGTCTTCCAGTCGTACTTGACCAATACACACCTGATATGGACCGTGTTCCTGAGTTTATGCTTTCTTTAGCTAATGATTACGAACTTATACTTCAAAATTTCCCCTCAACACAAGCGAAATTACATGTTTACACTGTAAGAACCCAAAAGCAGATTAATTCTCCTATTGGTGATGGTCTTGTACCCATTAGTAGGTTTCTTATTCATATAGAACATTTAGTAATGGAATTTAATGCTGCTGCTTTGCATAGCAAGGACAAAAGTTTCAAAGTTGGAGGCTTGGCTTGA

Coding sequence (CDS)

ATGGCAGATGATGTATTCGCACTGCTTCAGCATGGAACTCATCTCTATCTAGCGAATGTTGTGAATCTGAGCAAAGAACTCATGTATCAGCAAGTTTTGCGTCGATTTGCTCATTTTAATGCAATACAATTAAGCAACCCAGCCCCTCTATTCGAGTTACTTATTTTGGCACTGAAGGAGGAATATGCAAATTCAGAGTGTGAGAATGATGATTTTAATGAGAAGGTAGCTGAGACGAGTACAAAACTGCTCAAGTTGAAAGCTGAAATGCTGGAGGAATTTTTCTGCATAAGTATTGACAGAAATGGGAATTTGGCTAGTCTTCCAGTCGTACTTGACCAATACACACCTGATATGGACCGTGTTCCTGAGTTTATGCTTTCTTTAGCTAATGATTACGAACTTATACTTCAAAATTTCCCCTCAACACAAGCGAAATTACATGTTTACACTGTAAGAACCCAAAAGCAGATTAATTCTCCTATTGGTGATGGTCTTGTACCCATTAGTAGGTTTCTTATTCATATAGAACATTTAGTAATGGAATTTAATGCTGCTGCTTTGCATAGCAAGGACAAAAGTTTCAAAGTTGGAGGCTTGGCTTGA

Protein sequence

MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKEEYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMDRVPEFMLSLANDYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGLVPISRFLIHIEHLVMEFNAAALHSKDKSFKVGGLA*

Homology

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BLAST of MELO3C025010 vs. Swiss-Prot
Match: MLH1_ARATH (DNA mismatch repair protein MLH1 OS=Arabidopsis thaliana GN=MLH1 PE=2 SV=1)

HSP 1 Score: 191.8 bits (486), Expect = 7.2e-48
Identity = 102/169 (60.36%), Postives = 122/169 (72.19%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFAL+Q+ THLYLANVVNLSKELMYQQ LRRFAHFNAIQLS+PAPL EL++LALKE
Sbjct: 484 MADDVFALVQYNTHLYLANVVNLSKELMYQQTLRRFAHFNAIQLSDPAPLSELILLALKE 543

Query: 61  EYAN-SECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  +      DD  E++AE +T+LLK KAEMLEE+F + ID + NL+ LPV+LDQYTPDM
Sbjct: 544 EDLDPGNDTKDDLKERIAEMNTELLKEKAEMLEEYFSVHIDSSANLSRLPVILDQYTPDM 603

Query: 121 DRVPEFMLSLANDYELILQN--FPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF+L L ND E   +   F    A +  +       + +P GDG+
Sbjct: 604 DRVPEFLLCLGNDVEWEDEKSCFQGVSAAIGNFYAMHPPLLPNPSGDGI 652

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BLAST of MELO3C025010 vs. Swiss-Prot
Match: MLH1_MOUSE (DNA mismatch repair protein Mlh1 OS=Mus musculus GN=Mlh1 PE=1 SV=2)

HSP 1 Score: 109.0 bits (271), Expect = 6.1e-23
Identity = 57/127 (44.88%), Postives = 81/127 (63.78%), Query Frame = 1


Query: 6   FALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKEEYANS 65
           +AL QH T LYL N   LS+EL YQ ++  FA+F  ++LS PAPLF+L +LAL +   + 
Sbjct: 542 WALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLAL-DSPESG 601

Query: 66  ECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMDRVPEF 125
             E+D   E +AE   + LK KAEML ++F + ID  GNL  LP+++D Y P ++ +P F
Sbjct: 602 WTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIF 661

Query: 126 MLSLAND 133
           +L LA +
Sbjct: 662 ILRLATE 667

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BLAST of MELO3C025010 vs. Swiss-Prot
Match: MLH1_HUMAN (DNA mismatch repair protein Mlh1 OS=Homo sapiens GN=MLH1 PE=1 SV=1)

HSP 1 Score: 108.2 bits (269), Expect = 1.0e-22
Identity = 57/127 (44.88%), Postives = 79/127 (62.20%), Query Frame = 1


Query: 6   FALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKEEYANS 65
           +AL QH T LYL N   LS+EL YQ ++  FA+F  ++LS PAPLF+L +LAL +   + 
Sbjct: 538 WALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLAL-DSPESG 597

Query: 66  ECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMDRVPEF 125
             E D   E +AE   + LK KAEML ++F + ID  GNL  LP+++D Y P ++ +P F
Sbjct: 598 WTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIF 657

Query: 126 MLSLAND 133
           +L LA +
Sbjct: 658 ILRLATE 663

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BLAST of MELO3C025010 vs. Swiss-Prot
Match: MLH1_RAT (DNA mismatch repair protein Mlh1 OS=Rattus norvegicus GN=Mlh1 PE=2 SV=1)

HSP 1 Score: 103.6 bits (257), Expect = 2.6e-21
Identity = 54/127 (42.52%), Postives = 78/127 (61.42%), Query Frame = 1


Query: 6   FALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKEEYANS 65
           +AL QH T LYL N   LS+EL YQ ++  FA+F  ++L  PAPLF+  +LAL +   + 
Sbjct: 540 WALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLPEPAPLFDFAMLAL-DSPESG 599

Query: 66  ECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMDRVPEF 125
             E D   E +AE   + LK KA+ML ++F + ID  GNL  LP+++D Y P ++ +P F
Sbjct: 600 WTEEDGPKEGLAEYIVEFLKKKAKMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIF 659

Query: 126 MLSLAND 133
           +L LA +
Sbjct: 660 ILRLATE 665

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BLAST of MELO3C025010 vs. Swiss-Prot
Match: MLH1_DICDI (DNA mismatch repair protein Mlh1 OS=Dictyostelium discoideum GN=mlh1 PE=3 SV=1)

HSP 1 Score: 101.7 bits (252), Expect = 9.8e-21
Identity = 54/132 (40.91%), Postives = 81/132 (61.36%), Query Frame = 1


Query: 3   DDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKEEY 62
           D  +AL+Q G  LYL N+ N++KEL YQ  L RF+ F++I+ S    ++ LL+++L +  
Sbjct: 655 DHSYALVQFGKKLYLINLENITKELFYQLSLLRFSDFDSIKFSQSLSIYSLLLVSL-DSP 714

Query: 63  ANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMDRV 122
            +   E+D   +K+A+  TKLL  K E+L E+F I I+ +G L  +P VLD Y P  D +
Sbjct: 715 LSGWMESDGPKDKIADYLTKLLISKKELLNEYFSIEINEDGELVGIPQVLDHYVPCTDNL 774

Query: 123 PEFMLSLANDYE 135
           P F+L LA + E
Sbjct: 775 PIFLLKLATEVE 785

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BLAST of MELO3C025010 vs. TrEMBL
Match: A0A0A0K8W6_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_6G016960 PE=4 SV=1)

HSP 1 Score: 258.5 bits (659), Expect = 7.0e-66
Identity = 137/168 (81.55%), Postives = 142/168 (84.52%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE
Sbjct: 365 MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 424

Query: 61  EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 120
           E ANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCI IDRNGNLA LPVVLDQYTPDMD
Sbjct: 425 ENANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCIHIDRNGNLARLPVVLDQYTPDMD 484

Query: 121 RVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           RVPEFMLSLAN  D+E       S  A +  +       + +P GDGL
Sbjct: 485 RVPEFMLSLANDIDWEDEKTCLQSISAAIGNFYAMNPPLLPNPSGDGL 532

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BLAST of MELO3C025010 vs. TrEMBL
Match: A0A061FJV6_THECC (MUTL isoform 4 OS=Theobroma cacao GN=TCM_036511 PE=4 SV=1)

HSP 1 Score: 207.2 bits (526), Expect = 1.8e-50
Identity = 113/169 (66.86%), Postives = 128/169 (75.74%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQH THLYLANVVNLSKELMYQQVLRRFAHFNAIQLS  APL ELL+LALKE
Sbjct: 466 MADDVFALLQHNTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSESAPLQELLMLALKE 525

Query: 61  EYANSEC-ENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  + EC ENDD   K+AE +T+LLK KAEMLEE+FCI ID +GNL+ LP++LDQYTPDM
Sbjct: 526 EELDLECNENDDLKMKIAEMNTQLLKQKAEMLEEYFCIFIDSDGNLSRLPILLDQYTPDM 585

Query: 121 DRVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF+L L N  D+E     F S  A L  +       +  P G+GL
Sbjct: 586 DRVPEFLLCLGNDVDWEDEKNCFQSLAAALGNFYAMHPPLLPHPSGEGL 634

[Close]

BLAST of MELO3C025010 vs. TrEMBL
Match: A0A061FKD1_THECC (MUTL isoform 1 OS=Theobroma cacao GN=TCM_036511 PE=4 SV=1)

HSP 1 Score: 207.2 bits (526), Expect = 1.8e-50
Identity = 113/169 (66.86%), Postives = 128/169 (75.74%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQH THLYLANVVNLSKELMYQQVLRRFAHFNAIQLS  APL ELL+LALKE
Sbjct: 470 MADDVFALLQHNTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSESAPLQELLMLALKE 529

Query: 61  EYANSEC-ENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  + EC ENDD   K+AE +T+LLK KAEMLEE+FCI ID +GNL+ LP++LDQYTPDM
Sbjct: 530 EELDLECNENDDLKMKIAEMNTQLLKQKAEMLEEYFCIFIDSDGNLSRLPILLDQYTPDM 589

Query: 121 DRVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF+L L N  D+E     F S  A L  +       +  P G+GL
Sbjct: 590 DRVPEFLLCLGNDVDWEDEKNCFQSLAAALGNFYAMHPPLLPHPSGEGL 638

[Close]

BLAST of MELO3C025010 vs. TrEMBL
Match: A0A097PJN1_PLAAC (MLH1 (Fragment) OS=Platanus acerifolia PE=2 SV=1)

HSP 1 Score: 206.8 bits (525), Expect = 2.4e-50
Identity = 111/179 (62.01%), Postives = 133/179 (74.30%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQH T LYL NVVNLSKELMYQQVLRRFAHFNAIQLS+PAP+ EL+++ALKE
Sbjct: 453 MADDVFALLQHHTRLYLVNVVNLSKELMYQQVLRRFAHFNAIQLSDPAPIPELIMMALKE 512

Query: 61  EYANSEC-ENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  + EC ENDD  EK+AE +T+LLK KAEMLEE+FCI ID+ GNL+ LPV+LDQYTPDM
Sbjct: 513 EDLDPECNENDDLKEKIAEMNTELLKQKAEMLEEYFCIHIDQQGNLSRLPVILDQYTPDM 572

Query: 121 DRVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGLVPISRFLIHI 177
           D VPEF+L L N  D+E     F +  A L  +       + +P GDGL    + + H+
Sbjct: 573 DHVPEFVLCLGNDVDWEDEKNCFQAISAALGNFYALHPPLLPNPSGDGLQFYKKEIDHV 631

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BLAST of MELO3C025010 vs. TrEMBL
Match: W9RQW2_9ROSA (DNA mismatch repair protein Mlh1 OS=Morus notabilis GN=L484_003896 PE=4 SV=1)

HSP 1 Score: 205.3 bits (521), Expect = 7.0e-50
Identity = 112/169 (66.27%), Postives = 127/169 (75.15%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVF LLQH THLYLANVV+LSKELMYQQVLRRFAHFNAIQLS+PAPL +LL+LALKE
Sbjct: 498 MADDVFVLLQHDTHLYLANVVHLSKELMYQQVLRRFAHFNAIQLSDPAPLKDLLLLALKE 557

Query: 61  EYANSEC-ENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           +  + E  END+  EK+AE +T LLK KAEMLEE+FCI ID +GNLA LPVVLDQYTPDM
Sbjct: 558 DDLDPEYEENDELKEKIAEMNTDLLKQKAEMLEEYFCIHIDTHGNLARLPVVLDQYTPDM 617

Query: 121 DRVPEFMLSLAND--YELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF L L ND  +E     F    A L  +       + +P GDGL
Sbjct: 618 DRVPEFALCLGNDVNWENEKNCFQEIAASLGNFYAMHPPMLPNPSGDGL 666

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BLAST of MELO3C025010 vs. TAIR10
Match: AT4G09140.1 (AT4G09140.1 MUTL-homologue 1)

HSP 1 Score: 191.8 bits (486), Expect = 4.1e-49
Identity = 102/169 (60.36%), Postives = 122/169 (72.19%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFAL+Q+ THLYLANVVNLSKELMYQQ LRRFAHFNAIQLS+PAPL EL++LALKE
Sbjct: 484 MADDVFALVQYNTHLYLANVVNLSKELMYQQTLRRFAHFNAIQLSDPAPLSELILLALKE 543

Query: 61  EYAN-SECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  +      DD  E++AE +T+LLK KAEMLEE+F + ID + NL+ LPV+LDQYTPDM
Sbjct: 544 EDLDPGNDTKDDLKERIAEMNTELLKEKAEMLEEYFSVHIDSSANLSRLPVILDQYTPDM 603

Query: 121 DRVPEFMLSLANDYELILQN--FPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF+L L ND E   +   F    A +  +       + +P GDG+
Sbjct: 604 DRVPEFLLCLGNDVEWEDEKSCFQGVSAAIGNFYAMHPPLLPNPSGDGI 652

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BLAST of MELO3C025010 vs. NCBI nr
Match: gi|659126219|ref|XP_008463072.1| (PREDICTED: DNA mismatch repair protein MLH1 isoform X1 [Cucumis melo])

HSP 1 Score: 265.0 bits (676), Expect = 1.1e-67
Identity = 140/168 (83.33%), Postives = 145/168 (86.31%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE
Sbjct: 483 MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 542

Query: 61  EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 120
           EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD
Sbjct: 543 EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 602

Query: 121 RVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           RVPEFMLSLAN  D+E       S  A +  +       + +P GDGL
Sbjct: 603 RVPEFMLSLANDIDWEDEKTCLQSISAAIGNFYAMHPPLLPNPSGDGL 650

[Close]

BLAST of MELO3C025010 vs. NCBI nr
Match: gi|659126221|ref|XP_008463073.1| (PREDICTED: DNA mismatch repair protein MLH1 isoform X2 [Cucumis melo])

HSP 1 Score: 265.0 bits (676), Expect = 1.1e-67
Identity = 140/168 (83.33%), Postives = 145/168 (86.31%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE
Sbjct: 365 MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 424

Query: 61  EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 120
           EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD
Sbjct: 425 EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 484

Query: 121 RVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           RVPEFMLSLAN  D+E       S  A +  +       + +P GDGL
Sbjct: 485 RVPEFMLSLANDIDWEDEKTCLQSISAAIGNFYAMHPPLLPNPSGDGL 532

[Close]

BLAST of MELO3C025010 vs. NCBI nr
Match: gi|778709830|ref|XP_011656465.1| (PREDICTED: DNA mismatch repair protein MLH1 [Cucumis sativus])

HSP 1 Score: 258.5 bits (659), Expect = 1.0e-65
Identity = 137/168 (81.55%), Postives = 142/168 (84.52%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE
Sbjct: 483 MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 542

Query: 61  EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 120
           E ANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCI IDRNGNLA LPVVLDQYTPDMD
Sbjct: 543 ENANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCIHIDRNGNLARLPVVLDQYTPDMD 602

Query: 121 RVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           RVPEFMLSLAN  D+E       S  A +  +       + +P GDGL
Sbjct: 603 RVPEFMLSLANDIDWEDEKTCLQSISAAIGNFYAMNPPLLPNPSGDGL 650

[Close]

BLAST of MELO3C025010 vs. NCBI nr
Match: gi|700190674|gb|KGN45878.1| (hypothetical protein Csa_6G016960 [Cucumis sativus])

HSP 1 Score: 258.5 bits (659), Expect = 1.0e-65
Identity = 137/168 (81.55%), Postives = 142/168 (84.52%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE
Sbjct: 365 MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 424

Query: 61  EYANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDMD 120
           E ANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCI IDRNGNLA LPVVLDQYTPDMD
Sbjct: 425 ENANSECENDDFNEKVAETSTKLLKLKAEMLEEFFCIHIDRNGNLARLPVVLDQYTPDMD 484

Query: 121 RVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           RVPEFMLSLAN  D+E       S  A +  +       + +P GDGL
Sbjct: 485 RVPEFMLSLANDIDWEDEKTCLQSISAAIGNFYAMNPPLLPNPSGDGL 532

[Close]

BLAST of MELO3C025010 vs. NCBI nr
Match: gi|590603968|ref|XP_007020141.1| (MUTL isoform 4 [Theobroma cacao])

HSP 1 Score: 207.2 bits (526), Expect = 2.6e-50
Identity = 113/169 (66.86%), Postives = 128/169 (75.74%), Query Frame = 1


Query: 1   MADDVFALLQHGTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSNPAPLFELLILALKE 60
           MADDVFALLQH THLYLANVVNLSKELMYQQVLRRFAHFNAIQLS  APL ELL+LALKE
Sbjct: 466 MADDVFALLQHNTHLYLANVVNLSKELMYQQVLRRFAHFNAIQLSESAPLQELLMLALKE 525

Query: 61  EYANSEC-ENDDFNEKVAETSTKLLKLKAEMLEEFFCISIDRNGNLASLPVVLDQYTPDM 120
           E  + EC ENDD   K+AE +T+LLK KAEMLEE+FCI ID +GNL+ LP++LDQYTPDM
Sbjct: 526 EELDLECNENDDLKMKIAEMNTQLLKQKAEMLEEYFCIFIDSDGNLSRLPILLDQYTPDM 585

Query: 121 DRVPEFMLSLAN--DYELILQNFPSTQAKLHVYTVRTQKQINSPIGDGL 167
           DRVPEF+L L N  D+E     F S  A L  +       +  P G+GL
Sbjct: 586 DRVPEFLLCLGNDVDWEDEKNCFQSLAAALGNFYAMHPPLLPHPSGEGL 634

The following BLAST results are available for this feature:

BLAST of MELO3C025010 vs. Swiss-Prot


Match Name	E-value	Identity	Description
MLH1_ARATH	7.2e-48	60.36	DNA mismatch repair protein MLH1 OS=Arabidopsis thaliana GN=MLH1 PE=2 SV=1	[more]
MLH1_MOUSE	6.1e-23	44.88	DNA mismatch repair protein Mlh1 OS=Mus musculus GN=Mlh1 PE=1 SV=2	[more]
MLH1_HUMAN	1.0e-22	44.88	DNA mismatch repair protein Mlh1 OS=Homo sapiens GN=MLH1 PE=1 SV=1	[more]
MLH1_RAT	2.6e-21	42.52	DNA mismatch repair protein Mlh1 OS=Rattus norvegicus GN=Mlh1 PE=2 SV=1	[more]
MLH1_DICDI	9.8e-21	40.91	DNA mismatch repair protein Mlh1 OS=Dictyostelium discoideum GN=mlh1 PE=3 SV=1	[more]

BLAST of MELO3C025010 vs. TrEMBL


Match Name	E-value	Identity	Description
A0A0A0K8W6_CUCSA	7.0e-66	81.55	Uncharacterized protein OS=Cucumis sativus GN=Csa_6G016960 PE=4 SV=1	[more]
A0A061FJV6_THECC	1.8e-50	66.86	MUTL isoform 4 OS=Theobroma cacao GN=TCM_036511 PE=4 SV=1	[more]
A0A061FKD1_THECC	1.8e-50	66.86	MUTL isoform 1 OS=Theobroma cacao GN=TCM_036511 PE=4 SV=1	[more]
A0A097PJN1_PLAAC	2.4e-50	62.01	MLH1 (Fragment) OS=Platanus acerifolia PE=2 SV=1	[more]
W9RQW2_9ROSA	7.0e-50	66.27	DNA mismatch repair protein Mlh1 OS=Morus notabilis GN=L484_003896 PE=4 SV=1	[more]

BLAST of MELO3C025010 vs. TAIR10


Match Name	E-value	Identity	Description
AT4G09140.1	4.1e-49	60.36	MUTL-homologue 1	[more]

BLAST of MELO3C025010 vs. NCBI nr


Match Name	E-value	Identity	Description
gi\|659126219\|ref\|XP_008463072.1\|	1.1e-67	83.33	PREDICTED: DNA mismatch repair protein MLH1 isoform X1 [Cucumis melo]	[more]
gi\|659126221\|ref\|XP_008463073.1\|	1.1e-67	83.33	PREDICTED: DNA mismatch repair protein MLH1 isoform X2 [Cucumis melo]	[more]
gi\|778709830\|ref\|XP_011656465.1\|	1.0e-65	81.55	PREDICTED: DNA mismatch repair protein MLH1 [Cucumis sativus]	[more]
gi\|700190674\|gb\|KGN45878.1\|	1.0e-65	81.55	hypothetical protein Csa_6G016960 [Cucumis sativus]	[more]
gi\|590603968\|ref\|XP_007020141.1\|	2.6e-50	66.86	MUTL isoform 4 [Theobroma cacao]	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **INTERPRO**
Term	Definition

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0010154	fruit development
biological_process	GO:0006298	mismatch repair
biological_process	GO:0009791	post-embryonic development
biological_process	GO:0006312	mitotic recombination
biological_process	GO:0009555	pollen development
biological_process	GO:0048316	seed development
biological_process	GO:0009845	seed germination
cellular_component	GO:0032300	mismatch repair complex
cellular_component	GO:0000790	nuclear chromatin
cellular_component	GO:0005712	chiasma
cellular_component	GO:0032389	MutLalpha complex
cellular_component	GO:0000795	synaptonemal complex
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0030983	mismatched DNA binding
molecular_function	GO:0016887	ATPase activity
molecular_function	GO:0003697	single-stranded DNA binding

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MELO3C025010T1	MELO3C025010T1	mRNA

InterPro

Analysis Name: InterPro Annotations of melon
Date Performed: 2016-09-28


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	unknown	Coil	Coil	coord: 55..89 scor
None	No IPR available	PANTHER	PTHR10073	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL	coord: 1..132 score: 7.3
None	No IPR available	PANTHER	PTHR10073:SF40	DNA MISMATCH REPAIR PROTEIN MLH1	coord: 1..132 score: 7.3

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
MELO3C025010	Cla001013	Watermelon (97103) v1	mewmB312
MELO3C025010	ClCG08G002460	Watermelon (Charleston Gray)	mewcgB297
MELO3C025010	Cla97C08G146460	Watermelon (97103) v2	mewmbB304
MELO3C025010	Bhi04G001766	Wax gourd	mewgoB347
MELO3C025010	CSPI06G02520	Wild cucumber (PI 183967)	cpimeB468
MELO3C025010	Cucsa.365930	Cucumber (Gy14) v1	cgymeB592
MELO3C025010	CmaCh01G009340	Cucurbita maxima (Rimu)	cmameB414
MELO3C025010	CmoCh01G009510	Cucurbita moschata (Rifu)	cmomeB401
MELO3C025010	Lsi08G002350	Bottle gourd (USVL1VR-Ls)	lsimeB471
MELO3C025010	Cp4.1LG02g09410	Cucurbita pepo (Zucchini)	cpemeB512
MELO3C025010	CsGy6G002570	Cucumber (Gy14) v2	cgybmeB409
MELO3C025010	CsaV3_6G002720	Cucumber (Chinese Long) v3	cucmeB478

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
MELO3C025010	Cucurbita maxima (Rimu)	cmameB026
MELO3C025010	Cucurbita maxima (Rimu)	cmameB410
MELO3C025010	Cucurbita moschata (Rifu)	cmomeB015
MELO3C025010	Cucumber (Chinese Long) v2	cumeB415
MELO3C025010	Cucurbita pepo (Zucchini)	cpemeB721
MELO3C025010	Silver-seed gourd	carmeB0678