Csa2G021710 (gene) Cucumber (Chinese Long) v2 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	Csa2G021710
Type	gene
Organism	Cucumis. sativus (Cucumber (Chinese Long) v2)
Description	Tir-nbs-lrr resistance protein; contains IPR000157 (Toll/interleukin-1 receptor homology (TIR) domain)
Location	Chr2 : 2669560 .. 2670182 (+)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGTGGGAAAATGGGAGTGGTAGAGAAAAGTCTTTGGATGAAATTGGATAGGTTGTGTAGTACTGTATCAATCAAATTCAAAATACGATGCCCCACTTCTTCAATGCGTTTGATTTTCTCTCTTTATCTAATACATTGTTCTTCAATTTCTGCTCTGCATTATTCTTCATAAGTATTGCTATTGGTGTTTTCGATTTTTCTTTTCCTTATTCTGCGCGTTTCTTTCTGATGGATTCTTCCACTGTTGCAGCAGAATCATCTACTTTCAAATGGAGCTATGATGTGTGTTTGAGTTTCAGAGGAGAGGATACTCGAGACAATTTCACCAGTCATCTTGACATGGCCTTGCGTCAAAAGGGTGTCAACGTCTTCATTGACGACCAGCTCGAAAGGGGTGAGCAAATTTCTGAAACCCTTTTCAAATCTATACACAAAACTTCCATTTCTATTGTTATATTCTCTGAAAATTATGCATCTTCGACATGGTGTCTGGATGAATTGGTGGAAATAATTGAATGTAAGAAATCCAAGGGTCAGGAAGTTTTGCCGATTTTCTACAAGGTGGATCCTTCGGATGTACGAAAACAAACTGGTTGGTTTGGAGGAGCATTGGCCAAACATGA

mRNA sequence

ATGTGGGAAAATGGGAGTGCAGAATCATCTACTTTCAAATGGAGCTATGATGTGTGTTTGAGTTTCAGAGGAGAGGATACTCGAGACAATTTCACCAGTCATCTTGACATGGCCTTGCGTCAAAAGGGTGTCAACGTCTTCATTGACGACCAGCTCGAAAGGGAAATCCAAGGGTCAGGAAGTTTTGCCGATTTTCTACAAGGTGGATCCTTCGGATGTACGAAAACAAACTGGTTGGTTTGGAGGAGCATTGGCCAAACATGA

Coding sequence (CDS)

ATGTGGGAAAATGGGAGTGCAGAATCATCTACTTTCAAATGGAGCTATGATGTGTGTTTGAGTTTCAGAGGAGAGGATACTCGAGACAATTTCACCAGTCATCTTGACATGGCCTTGCGTCAAAAGGGTGTCAACGTCTTCATTGACGACCAGCTCGAAAGGGAAATCCAAGGGTCAGGAAGTTTTGCCGATTTTCTACAAGGTGGATCCTTCGGATGTACGAAAACAAACTGGTTGGTTTGGAGGAGCATTGGCCAAACATGA

Protein sequence

MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSGSFADFLQGGSFGCTKTNWLVWRSIGQT*

Homology

[Close]

BLAST of Csa2G021710 vs. Swiss-Prot
Match: TMVRN_NICGU (TMV resistance protein N OS=Nicotiana glutinosa GN=N PE=1 SV=1)

HSP 1 Score: 59.3 bits (142), Expect = 2.4e-08
Identity = 27/46 (58.70%), Postives = 31/46 (67.39%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQ 52
          ++ SS+ +WSYDV LSFRGEDTR  FTSHL   L  KG+  F DD+
Sbjct: 2  ASSSSSSRWSYDVFLSFRGEDTRKTFTSHLYEVLNDKGIKTFQDDK 47

[Close]

BLAST of Csa2G021710 vs. Swiss-Prot
Match: Y4117_ARATH (Putative disease resistance protein At4g11170 OS=Arabidopsis thaliana GN=At4g11170 PE=2 SV=1)

HSP 1 Score: 52.8 bits (125), Expect = 2.3e-06
Identity = 25/48 (52.08%), Postives = 28/48 (58.33%), Query Frame = 1


Query: 7  AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          A SS+  W YDV  SFRGED R+NF SHL      KG+  F DD ++R
Sbjct: 2  ASSSSNSWRYDVFPSFRGEDVRNNFLSHLLKEFESKGIVTFRDDHIKR 49

[Close]

BLAST of Csa2G021710 vs. TrEMBL
Match: A0A0A0LFS0_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_2G021710 PE=4 SV=1)

HSP 1 Score: 186.8 bits (473), Expect = 1.1e-44
Identity = 87/87 (100.00%), Postives = 87/87 (100.00%), Query Frame = 1


Query: 1  MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG 60
          MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG
Sbjct: 1  MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG 60

Query: 61 SFADFLQGGSFGCTKTNWLVWRSIGQT 88
          SFADFLQGGSFGCTKTNWLVWRSIGQT
Sbjct: 61 SFADFLQGGSFGCTKTNWLVWRSIGQT 87

[Close]

BLAST of Csa2G021710 vs. TrEMBL
Match: E7CHD1_CUCSA (Putative TIR-NBS class protein OS=Cucumis sativus PE=4 SV=1)

HSP 1 Score: 102.8 bits (255), Expect = 2.1e-19
Identity = 48/49 (97.96%), Postives = 49/49 (100.00%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          +AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER
Sbjct: 7  AAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55

[Close]

BLAST of Csa2G021710 vs. TrEMBL
Match: E5GB34_CUCME (TIR-NBS-LRR disease resistance protein OS=Cucumis melo subsp. melo PE=4 SV=1)

HSP 1 Score: 95.9 bits (237), Expect = 2.6e-17
Identity = 49/64 (76.56%), Postives = 52/64 (81.25%), Query Frame = 1


Query: 4  NGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSGSFA 63
          + S ESSTFKWSYDV LSFRGEDTR NFTSHLDMALRQKGVNVFIDD+LER  Q S S  
Sbjct: 2  DSSTESSTFKWSYDVFLSFRGEDTRTNFTSHLDMALRQKGVNVFIDDKLERGEQISESLF 61

Query: 64 DFLQ 68
            +Q
Sbjct: 62 KSIQ 65

[Close]

BLAST of Csa2G021710 vs. TrEMBL
Match: E7CHD3_CUCSA (Putative TIR-NBS-LRR-AAA+ATPase OS=Cucumis sativus PE=4 SV=1)

HSP 1 Score: 90.1 bits (222), Expect = 1.4e-15
Identity = 46/65 (70.77%), Postives = 51/65 (78.46%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSGSFADF 65
          + ES TFKW+YDV LSFRGEDTR NFTSHLDMALRQKGVNVFI+D+LER  Q S S    
Sbjct: 7  ATESPTFKWTYDVFLSFRGEDTRTNFTSHLDMALRQKGVNVFINDKLERGEQISESLFKS 66

Query: 66 LQGGS 71
          +Q  S
Sbjct: 67 IQEAS 71

[Close]

BLAST of Csa2G021710 vs. TrEMBL
Match: D9I8I4_CUCSA (TIR-NBS-LRR-AAA+ATPase class resistance protein OS=Cucumis sativus PE=4 SV=1)

HSP 1 Score: 90.1 bits (222), Expect = 1.4e-15
Identity = 46/65 (70.77%), Postives = 51/65 (78.46%), Query Frame = 1


Query: 6   SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSGSFADF 65
           + ES TFKW+YDV LSFRGEDTR NFTSHLDMALRQKGVNVFID++LER  Q S S    
Sbjct: 37  ATESPTFKWTYDVFLSFRGEDTRTNFTSHLDMALRQKGVNVFIDNKLERGEQISESLFKS 96

Query: 66  LQGGS 71
           +Q  S
Sbjct: 97  IQEAS 101

[Close]

BLAST of Csa2G021710 vs. TAIR10
Match: AT4G12010.1 (AT4G12010.1 Disease resistance protein (TIR-NBS-LRR class) family)

HSP 1 Score: 55.8 bits (133), Expect = 1.5e-08
Identity = 27/46 (58.70%), Postives = 31/46 (67.39%), Query Frame = 1


Query: 9  SSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          SS     +DV LSFRG DTR+NFT HL  ALR +G++ FIDD+L R
Sbjct: 4  SSPSSAEFDVFLSFRGFDTRNNFTGHLQKALRLRGIDSFIDDRLRR 49

[Close]

BLAST of Csa2G021710 vs. TAIR10
Match: AT5G51630.1 (AT5G51630.1 Disease resistance protein (TIR-NBS-LRR class) family)

HSP 1 Score: 53.9 bits (128), Expect = 5.8e-08
Identity = 25/48 (52.08%), Postives = 30/48 (62.50%), Query Frame = 1


Query: 7  AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          A SS+  W+YDV  SF GED R +F SHL   L +K +N FID+ +ER
Sbjct: 2  ASSSSRSWTYDVFPSFSGEDVRKSFLSHLLKKLHRKSINTFIDNNIER 49

[Close]

BLAST of Csa2G021710 vs. TAIR10
Match: AT4G11170.1 (AT4G11170.1 Disease resistance protein (TIR-NBS-LRR class) family)

HSP 1 Score: 52.8 bits (125), Expect = 1.3e-07
Identity = 25/48 (52.08%), Postives = 28/48 (58.33%), Query Frame = 1


Query: 7  AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          A SS+  W YDV  SFRGED R+NF SHL      KG+  F DD ++R
Sbjct: 2  ASSSSNSWRYDVFPSFRGEDVRNNFLSHLLKEFESKGIVTFRDDHIKR 49

[Close]

BLAST of Csa2G021710 vs. TAIR10
Match: AT1G72860.1 (AT1G72860.1 Disease resistance protein (TIR-NBS-LRR class) family)

HSP 1 Score: 52.0 bits (123), Expect = 2.2e-07
Identity = 26/46 (56.52%), Postives = 28/46 (60.87%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQ 52
          ++ SS+  W YDV LSFRGEDTR N  SHL   L  KGV  F DD+
Sbjct: 2  ASSSSSPIWKYDVFLSFRGEDTRKNIVSHLHKQLVDKGVVTFKDDK 47

[Close]

BLAST of Csa2G021710 vs. TAIR10
Match: AT4G19530.1 (AT4G19530.1 disease resistance protein (TIR-NBS-LRR class) family)

HSP 1 Score: 51.6 bits (122), Expect = 2.9e-07
Identity = 24/49 (48.98%), Postives = 33/49 (67.35%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          S+  S+    + V L+FRG++ R+NF SHLD ALR K +NVFID+ +E+
Sbjct: 5  SSVVSSVPQQHQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEK 53

[Close]

BLAST of Csa2G021710 vs. NCBI nr
Match: gi|700205781|gb|KGN60900.1| (hypothetical protein Csa_2G021710 [Cucumis sativus])

HSP 1 Score: 186.8 bits (473), Expect = 1.6e-44
Identity = 87/87 (100.00%), Postives = 87/87 (100.00%), Query Frame = 1


Query: 1  MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG 60
          MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG
Sbjct: 1  MWENGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSG 60

Query: 61 SFADFLQGGSFGCTKTNWLVWRSIGQT 88
          SFADFLQGGSFGCTKTNWLVWRSIGQT
Sbjct: 61 SFADFLQGGSFGCTKTNWLVWRSIGQT 87

[Close]

BLAST of Csa2G021710 vs. NCBI nr
Match: gi|778666793|ref|XP_004139181.2| (PREDICTED: TMV resistance protein N-like isoform X1 [Cucumis sativus])

HSP 1 Score: 102.8 bits (255), Expect = 3.1e-19
Identity = 48/49 (97.96%), Postives = 49/49 (100.00%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          +AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER
Sbjct: 7  AAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55

[Close]

BLAST of Csa2G021710 vs. NCBI nr
Match: gi|315507081|gb|ADU33176.1| (putative TIR-NBS class protein [Cucumis sativus])

HSP 1 Score: 102.8 bits (255), Expect = 3.1e-19
Identity = 48/49 (97.96%), Postives = 49/49 (100.00%), Query Frame = 1


Query: 6  SAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          +AESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER
Sbjct: 7  AAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55

[Close]

BLAST of Csa2G021710 vs. NCBI nr
Match: gi|778666797|ref|XP_011648811.1| (PREDICTED: toll/interleukin-1 receptor-like protein isoform X2 [Cucumis sativus])

HSP 1 Score: 100.9 bits (250), Expect = 1.2e-18
Identity = 47/47 (100.00%), Postives = 47/47 (100.00%), Query Frame = 1


Query: 8  ESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 55
          ESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER
Sbjct: 3  ESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLER 49

[Close]

BLAST of Csa2G021710 vs. NCBI nr
Match: gi|659070337|ref|XP_008454622.1| (PREDICTED: LOW QUALITY PROTEIN: TMV resistance protein N-like [Cucumis melo])

HSP 1 Score: 95.9 bits (237), Expect = 3.7e-17
Identity = 49/64 (76.56%), Postives = 52/64 (81.25%), Query Frame = 1


Query: 4  NGSAESSTFKWSYDVCLSFRGEDTRDNFTSHLDMALRQKGVNVFIDDQLEREIQGSGSFA 63
          + S ESSTFKWSYDV LSFRGEDTR NFTSHLDMALRQKGVNVFIDD+LER  Q S S  
Sbjct: 27 DSSTESSTFKWSYDVFLSFRGEDTRTNFTSHLDMALRQKGVNVFIDDKLERGEQISESLF 86

Query: 64 DFLQ 68
            +Q
Sbjct: 87 KSIQ 90

The following BLAST results are available for this feature:

BLAST of Csa2G021710 vs. Swiss-Prot


Match Name	E-value	Identity	Description
TMVRN_NICGU	2.4e-08	58.70	TMV resistance protein N OS=Nicotiana glutinosa GN=N PE=1 SV=1	[more]
Y4117_ARATH	2.3e-06	52.08	Putative disease resistance protein At4g11170 OS=Arabidopsis thaliana GN=At4g111...	[more]

BLAST of Csa2G021710 vs. TrEMBL


Match Name	E-value	Identity	Description
A0A0A0LFS0_CUCSA	1.1e-44	100.00	Uncharacterized protein OS=Cucumis sativus GN=Csa_2G021710 PE=4 SV=1	[more]
E7CHD1_CUCSA	2.1e-19	97.96	Putative TIR-NBS class protein OS=Cucumis sativus PE=4 SV=1	[more]
E5GB34_CUCME	2.6e-17	76.56	TIR-NBS-LRR disease resistance protein OS=Cucumis melo subsp. melo PE=4 SV=1	[more]
E7CHD3_CUCSA	1.4e-15	70.77	Putative TIR-NBS-LRR-AAA+ATPase OS=Cucumis sativus PE=4 SV=1	[more]
D9I8I4_CUCSA	1.4e-15	70.77	TIR-NBS-LRR-AAA+ATPase class resistance protein OS=Cucumis sativus PE=4 SV=1	[more]

BLAST of Csa2G021710 vs. TAIR10


Match Name	E-value	Identity	Description
AT4G12010.1	1.5e-08	58.70	Disease resistance protein (TIR-NBS-LRR class) family	[more]
AT5G51630.1	5.8e-08	52.08	Disease resistance protein (TIR-NBS-LRR class) family	[more]
AT4G11170.1	1.3e-07	52.08	Disease resistance protein (TIR-NBS-LRR class) family	[more]
AT1G72860.1	2.2e-07	56.52	Disease resistance protein (TIR-NBS-LRR class) family	[more]
AT4G19530.1	2.9e-07	48.98	disease resistance protein (TIR-NBS-LRR class) family	[more]

BLAST of Csa2G021710 vs. NCBI nr


Match Name	E-value	Identity	Description
gi\|700205781\|gb\|KGN60900.1\|	1.6e-44	100.00	hypothetical protein Csa_2G021710 [Cucumis sativus]	[more]
gi\|778666793\|ref\|XP_004139181.2\|	3.1e-19	97.96	PREDICTED: TMV resistance protein N-like isoform X1 [Cucumis sativus]	[more]
gi\|315507081\|gb\|ADU33176.1\|	3.1e-19	97.96	putative TIR-NBS class protein [Cucumis sativus]	[more]
gi\|778666797\|ref\|XP_011648811.1\|	1.2e-18	100.00	PREDICTED: toll/interleukin-1 receptor-like protein isoform X2 [Cucumis sativus]	[more]
gi\|659070337\|ref\|XP_008454622.1\|	3.7e-17	76.56	PREDICTED: LOW QUALITY PROTEIN: TMV resistance protein N-like [Cucumis melo]	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **INTERPRO**
Term	Definition
IPR000157	TIR_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
cellular_component	GO:0005575	cellular_component
molecular_function	GO:0043531	ADP binding
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0005515	protein binding
molecular_function	GO:0032559	adenyl ribonucleotide binding

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Csa2G021710.1	Csa2G021710.1	mRNA

InterPro

Analysis Name: InterPro Annotations of cucumber (Chinese Long)
Date Performed: 2016-09-28


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000157	Toll/interleukin-1 receptor homology (TIR) domain	GENE3D	G3DSA:3.40.50.10140		coord: 14..51 score: 5.
IPR000157	Toll/interleukin-1 receptor homology (TIR) domain	PFAM	PF01582	TIR	coord: 16..51 score: 2.
IPR000157	Toll/interleukin-1 receptor homology (TIR) domain	unknown	SSF52200	Toll/Interleukin receptor TIR domain	coord: 7..64 score: 2.88
None	No IPR available	PANTHER	PTHR11017	LEUCINE-RICH REPEAT-CONTAINING PROTEIN	coord: 6..54 score: 5.1

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
Csa2G021710	CSPI02G03890	Wild cucumber (PI 183967)	cpicuB065
Csa2G021710	Cucsa.091530	Cucumber (Gy14) v1	cgycuB096
Csa2G021710	CmoCh05G011800	Cucurbita moschata (Rifu)	cmocuB782
Csa2G021710	CsGy2G003960	Cucumber (Gy14) v2	cgybcuB056

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
Csa2G021710	Wax gourd	cuwgoB150
Csa2G021710	Cucurbita maxima (Rimu)	cmacuB173
Csa2G021710	Cucurbita maxima (Rimu)	cmacuB791
Csa2G021710	Cucurbita moschata (Rifu)	cmocuB157
Csa2G021710	Cucurbita moschata (Rifu)	cmocuB783
Csa2G021710	Melon (DHL92) v3.5.1	cumeB139
Csa2G021710	Melon (DHL92) v3.5.1	cumeB144
Csa2G021710	Watermelon (Charleston Gray)	cuwcgB122
Csa2G021710	Watermelon (97103) v1	cuwmB147
Csa2G021710	Cucurbita pepo (Zucchini)	cpecuB103
Csa2G021710	Cucurbita pepo (Zucchini)	cpecuB820
Csa2G021710	Bottle gourd (USVL1VR-Ls)	culsiB098
Csa2G021710	Melon (DHL92) v3.6.1	cumedB132
Csa2G021710	Silver-seed gourd	carcuB0735
Csa2G021710	Silver-seed gourd	carcuB0917
Csa2G021710	Watermelon (97103) v2	cuwmbB118