Cla002115 (gene) Watermelon (97103) v1 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	Cla002115
Type	gene
Organism	Citrullus. lanatus (Watermelon (97103) v1)
Description	Niemann-pick C1 (Fragment) (AHRD V1 **-- Q17FP9_AEDAE); contains Interpro domain(s) IPR003392 Patched
Location	Chr2 : 15085033 .. 15087062 (-)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGCTCTTGTTACTAAAAACTCGGGGACTAAAAAGGTAATTTTTCCATTTTTTAAAAAAATTTAATTTTTTATTTTTGGAAAGTATGCTAGGAGAATTTTTAACCTGATAACTCTAATTACGTTTCAAGGGCATAGCACATAGTTAAATATCTTGTTCATCTTTCTTAAACAAACTATTGTTATATTATTGATAATATAGGTCCCCGTGTTATTTTATTGGCTTTATTAATGTCTTAACCAGATTTCTAAGAATCTCATTGAGGATTTTCTGTGATGCAATTGCAGGTGCCATATTTATTGTCTCTCTGGTTATCACATCTAGGTATGAATATCATTTTGTTTTTGTGTTTGGCTGACATTTATTACAAGGTTCTTTTTGTAGTGTGAAAATGCCACTTCTTTATTTGATTATACTTTGATCTATTGGTTTTGAAATGCAGTTTGTGGAGTTCAGGAATTATTATACTTGTTTTGGCTATGATTGTTATTGATCTCATGGTATCTCTCTCTTGCTACAATGACTCCATTACTTATATTTCCTTTTAGAGGAGTCTATTGCATTTTTATTTTATTCGTTTATTAATTTATGAGTTTCTATTCCCGTTTGTGTATGTTTTGACTTTGTGAAGTCAGTTGTTTTCAGAAGTGTTGATTTCTCTTTTTCGTTTTTGGCAGGGAGTAATGGCAGTTCTGAAAATTCAACTAAATGCAGTCTCTGTTGTTAACATATTAATGTCAATAGGAATTGCTGTTGAGTTTTGCATCCATTTAGTTCATGCATTTTTGGTTAGTACCAACCCTAATCACTTCATCAGGCTATTTAAATTCATGGTTTAATTTACTAATTTCACTTATTCGAAGACATGCAAAGTTTTTGGGGCTTAAGTAATCGTGAACCCATGGTGTGGTTTCTGGTGGTCATGGTGGAGTACTGGCACATGTTTTAATCACCAGACCATTGATTAGCATGCTATTATATGGGAAATGCTATGGAGTCAAATAGCTAGCTTATTACTGGATGACGGACCTTGTGTCTTACCCTTTTATTATTATTATTATTATTATTGACTTTATGATTTAATAACATATTTGACCAAATGCCCTCATGTAGGTTAGCTGCGGTGACAGAAGCCAGCGAGCACAGGAGGCTTTGAGTACAGTGGGAGCCTCTGTATTCAGGTAGACATTGTGTTTGATTTTCTTATTTTGTTGCTACAACATATTCAGTTTTTGGTGCATCTCGGGATCGTATTCAATAAAAGATGGATGGCTTCCATTGTTGGAAGATTTGACTGTAAAAGAAACAATTTCCCGCGATGCTTTCTACTTTATGGAAGTGTTACATTTGACTCAGTTTTTCGTTGTGCATGACTACTCAACATTTTCTAAAAGAGGTGTATTTCTACTTCTCGCTATACTAGTTACTCTTCGAATCAGTTACTTAAAAAAACGATTCTTTCCATTTTAATTTTAAAAAGTAAAGAGGATATTTCTCATAATCATTATGACCTATGAGTTCTCTTTGAAAGTTTGTCAGGTTCCTGTCTTGCGCCCCAGCATCCACATGATGCCATTTTGCAGAAATTAATATTTACACTTTTTTTGCAGTGGGATTACTCTCACGAAACTGGTTGGGGTCATCGTTCTTTGCTTCGCGAAATCAGAAATATTTGTGGTATCTGATTTCTTGGCCTTATTCCTTATTACAAATTCATGTTACTTTCTTTTGAGATCTAAAAGAAGACAAATATTGGCTATGTGGATTCTGCAGGTTTATTACTTCCAAATGTACCTTGCATTGGTCATTATTGGTTTCCTCCATGGCCTCGTTTTTCTACCTGTAAGTTCAGAAACTATCCAATATTCTTATAATTACCGACATCATCCCGTCTTCTATGGAGGAAGTCATTGAGCCATTTATTACATATCTGGTTGTCCTTCGCAGGTAATATTGAGTATGATTGGACCACCATCAAGATACTTAGTTGAAGATGATGCTCCTACGGAAACTGAGCTGCTTGTTTCATAA

mRNA sequence

ATGCTCTTGTTACTAAAAACTCGGGGACTAAAAAGATTTCTAAGAATCTCATTGAGGATTTTCTGTGATGCAATTGCAGGTGCCATATTTATTGTCTCTCTGGTTATCACATCTAGTTTGTGGAGTTCAGGAATTATTATACTTGTTTTGGCTATGATTGTTATTGATCTCATGGGAGTAATGGCAGTTCTGAAAATTCAACTAAATGCAGTCTCTGTTGTTAACATATTAATGTCAATAGGAATTGCTGTTGAGTTTTGCATCCATTTAGTTCATGCATTTTTGGTTAGCTGCGGTGACAGAAGCCAGCGAGCACAGGAGGCTTTGAGTACAGTGGGAGCCTCTGTATTCAGTGGGATTACTCTCACGAAACTGGTTGGGGTCATCGTTCTTTGCTTCGCGAAATCAGAAATATTTGTGGTTTATTACTTCCAAATGTACCTTGCATTGGTCATTATTGGTTTCCTCCATGGCCTCGTTTTTCTACCTGTAATATTGAGTATGATTGGACCACCATCAAGATACTTAGTTGAAGATGATGCTCCTACGGAAACTGAGCTGCTTGTTTCATAA

Coding sequence (CDS)

ATGCTCTTGTTACTAAAAACTCGGGGACTAAAAAGATTTCTAAGAATCTCATTGAGGATTTTCTGTGATGCAATTGCAGGTGCCATATTTATTGTCTCTCTGGTTATCACATCTAGTTTGTGGAGTTCAGGAATTATTATACTTGTTTTGGCTATGATTGTTATTGATCTCATGGGAGTAATGGCAGTTCTGAAAATTCAACTAAATGCAGTCTCTGTTGTTAACATATTAATGTCAATAGGAATTGCTGTTGAGTTTTGCATCCATTTAGTTCATGCATTTTTGGTTAGCTGCGGTGACAGAAGCCAGCGAGCACAGGAGGCTTTGAGTACAGTGGGAGCCTCTGTATTCAGTGGGATTACTCTCACGAAACTGGTTGGGGTCATCGTTCTTTGCTTCGCGAAATCAGAAATATTTGTGGTTTATTACTTCCAAATGTACCTTGCATTGGTCATTATTGGTTTCCTCCATGGCCTCGTTTTTCTACCTGTAATATTGAGTATGATTGGACCACCATCAAGATACTTAGTTGAAGATGATGCTCCTACGGAAACTGAGCTGCTTGTTTCATAA

Protein sequence

MLLLLKTRGLKRFLRISLRIFCDAIAGAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEFCIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS

Homology

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BLAST of Cla002115 vs. Swiss-Prot
Match: NPC1_HUMAN (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 167.5 bits (423), Expect = 1.4e-40
Identity = 83/147 (56.46%), Postives = 115/147 (78.23%), Query Frame = 1


Query: 27   GAIFIVSLVITS-SLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVE 86
            GAIF+V++V+    LWS+ I+   +AM+++++ GVM +  I LNAVS+VN++MS GI+VE
Sbjct: 1107 GAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVE 1166

Query: 87   FCIHLVHAFLVSC-GDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYF 146
            FC H+  AF VS  G R +RA+EAL+ +G+SVFSGITLTK  G++VL FAKS+IF ++YF
Sbjct: 1167 FCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYF 1226

Query: 147  QMYLALVIIGFLHGLVFLPVILSMIGP 172
            +MYLA+V++G  HGL+FLPV+LS IGP
Sbjct: 1227 RMYLAMVLLGATHGLIFLPVLLSYIGP 1253

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BLAST of Cla002115 vs. Swiss-Prot
Match: NPC1_MOUSE (Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2)

HSP 1 Score: 167.2 bits (422), Expect = 1.8e-40
Identity = 83/147 (56.46%), Postives = 115/147 (78.23%), Query Frame = 1


Query: 27   GAIFIVSLVITS-SLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVE 86
            G+IF+V+LV+    LWS+ I+ + +AMI++++ GVM +  I LNAVS+VN++MS GI+VE
Sbjct: 1106 GSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVE 1165

Query: 87   FCIHLVHAFLVSC-GDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYF 146
            FC H+  AF +S  G R  RA+EAL+ +G+SVFSGITLTK  G++VL FAKS+IF ++YF
Sbjct: 1166 FCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYF 1225

Query: 147  QMYLALVIIGFLHGLVFLPVILSMIGP 172
            +MYLA+V++G  HGL+FLPV+LS IGP
Sbjct: 1226 RMYLAMVLLGATHGLIFLPVLLSYIGP 1252

[Close]

BLAST of Cla002115 vs. Swiss-Prot
Match: NPC1_PIG (Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1)

HSP 1 Score: 165.2 bits (417), Expect = 6.8e-40
Identity = 82/147 (55.78%), Postives = 115/147 (78.23%), Query Frame = 1


Query: 27   GAIFIVSLVITS-SLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVE 86
            GAIF+V++V+    LW++ I+ + +AMI++++ GVM +  I LNAVS+VN++MS GI+VE
Sbjct: 1106 GAIFLVTVVLMGCELWATVIMCVTIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVE 1165

Query: 87   FCIHLVHAFLVSC-GDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYF 146
            FC H+  AF +S  G R  RA+EAL+ +G+SVFSGITLTK  G++VL FAKS+IF ++YF
Sbjct: 1166 FCSHITRAFTLSTKGSRVDRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYF 1225

Query: 147  QMYLALVIIGFLHGLVFLPVILSMIGP 172
            +MYLA+V++G  HGL+FLPV+LS IGP
Sbjct: 1226 RMYLAIVLLGATHGLIFLPVLLSYIGP 1252

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BLAST of Cla002115 vs. Swiss-Prot
Match: NPC1_YEAST (Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NCR1 PE=1 SV=1)

HSP 1 Score: 140.6 bits (353), Expect = 1.8e-32
Identity = 72/162 (44.44%), Postives = 110/162 (67.90%), Query Frame = 1


Query: 16   ISLRIFCDAIAGAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVN 75
            ++L++   AI   IF +S V   ++ SS ++ LV+ MI++D+  +MA+L I LNAVS+VN
Sbjct: 1000 LTLKLIGSAII-LIFFISSVFLQNIRSSFLLALVVTMIIVDIGALMALLGISLNAVSLVN 1059

Query: 76   ILMSIGIAVEFCIHLVHAFLV----SCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVL 135
            +++ +G+ VEFC+H+V +F V    +  D + R   +L+T+G SV  GITLTK +GV VL
Sbjct: 1060 LIICVGLGVEFCVHIVRSFTVVPSETKKDANSRVLYSLNTIGESVIKGITLTKFIGVCVL 1119

Query: 136  CFAKSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPS 174
             FA+S+IF V+YF+M+  L+I+  LH L+FLP +LS+ G  S
Sbjct: 1120 AFAQSKIFDVFYFRMWFTLIIVAALHALLFLPALLSLFGGES 1160

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BLAST of Cla002115 vs. Swiss-Prot
Match: PTC1_HUMAN (Protein patched homolog 1 OS=Homo sapiens GN=PTCH1 PE=1 SV=2)

HSP 1 Score: 121.7 bits (304), Expect = 8.6e-27
Identity = 64/158 (40.51%), Postives = 100/158 (63.29%), Query Frame = 1


Query: 14   LRISLRIFCDAIAGAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSV 73
            LR  L +F   +    F+V  V   + W++GII++VLA++ ++L G+M ++ I+L+AV V
Sbjct: 1024 LRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPV 1083

Query: 74   VNILMSIGIAVEFCIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCF 133
            V ++ S+GI VEF +H+  AFL + GD+++RA  AL  + A V  G   T L+GV++L  
Sbjct: 1084 VILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVST-LLGVLMLAG 1143

Query: 134  AKSEIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGP 172
            ++ +  V Y+F +   L I+G L+GLV LPV+LS  GP
Sbjct: 1144 SEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGP 1180

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BLAST of Cla002115 vs. TrEMBL
Match: A0A0A0KAC3_CUCSA (Uncharacterized protein OS=Cucumis sativus GN=Csa_6G120400 PE=4 SV=1)

HSP 1 Score: 300.4 bits (768), Expect = 1.5e-78
Identity = 156/164 (95.12%), Postives = 161/164 (98.17%), Query Frame = 1


Query: 27  GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
           GAIFIVSLVITSSLWSSG+IILVLAMIVIDL+GVMAVLKIQLNAVSVVNILMSIGIAVEF
Sbjct: 32  GAIFIVSLVITSSLWSSGMIILVLAMIVIDLLGVMAVLKIQLNAVSVVNILMSIGIAVEF 91

Query: 87  CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
           C+HLVHAF VSCGDRSQRAQEALST+GASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM
Sbjct: 92  CVHLVHAFSVSCGDRSQRAQEALSTIGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 151

Query: 147 YLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS 191
           YLALVIIGFLHGLVFLPVILSMIGPPSRYL+ DDAP ETELLVS
Sbjct: 152 YLALVIIGFLHGLVFLPVILSMIGPPSRYLISDDAPMETELLVS 195

[Close]

BLAST of Cla002115 vs. TrEMBL
Match: T2D239_PHAVU (Uncharacterized protein OS=Phaseolus vulgaris PE=4 SV=1)

HSP 1 Score: 255.0 bits (650), Expect = 7.3e-65
Identity = 131/172 (76.16%), Postives = 149/172 (86.63%), Query Frame = 1


Query: 16  ISLRIFCDAIAGAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVN 75
           I++ I    IAGAIF+V LVITSSLWSS I++LVL MI++DLMGVMA+L IQLNAVSVVN
Sbjct: 248 INITIALGDIAGAIFVVCLVITSSLWSSAIVLLVLVMIILDLMGVMAILGIQLNAVSVVN 307

Query: 76  ILMSIGIAVEFCIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAK 135
           ++MS+GIAVEFC+H+VHAF VS GDRSQRA+ AL TVGASVFSGITLTKLVGVIVLCF+ 
Sbjct: 308 LVMSLGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTVGASVFSGITLTKLVGVIVLCFST 367

Query: 136 SEIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYLV-----EDDAP 183
           SE+FVVYYFQMYLALVIIGFLHGLVFLPV+LS+ GPP RY V     EDD P
Sbjct: 368 SELFVVYYFQMYLALVIIGFLHGLVFLPVVLSLFGPPLRYTVIKEQLEDDVP 419

[Close]

BLAST of Cla002115 vs. TrEMBL
Match: V7B9Q8_PHAVU (Uncharacterized protein OS=Phaseolus vulgaris GN=PHAVU_008G291900g PE=4 SV=1)

HSP 1 Score: 251.1 bits (640), Expect = 1.0e-63
Identity = 128/163 (78.53%), Postives = 144/163 (88.34%), Query Frame = 1


Query: 27   GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
            GAIF+V LVITSSLWSS I++LVL MI++DLMGVMA+L IQLNAVSVVN++MS+GIAVEF
Sbjct: 1118 GAIFVVCLVITSSLWSSAIVLLVLVMIILDLMGVMAILGIQLNAVSVVNLVMSLGIAVEF 1177

Query: 87   CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
            C+H+VHAF VS GDRSQRA+ AL TVGASVFSGITLTKLVGVIVLCF+ SE+FVVYYFQM
Sbjct: 1178 CVHIVHAFTVSLGDRSQRAKTALCTVGASVFSGITLTKLVGVIVLCFSTSELFVVYYFQM 1237

Query: 147  YLALVIIGFLHGLVFLPVILSMIGPPSRYLV-----EDDAPTE 185
            YLALVIIGFLHGLVFLPV+LS+ GPP RY V     EDD P E
Sbjct: 1238 YLALVIIGFLHGLVFLPVLLSLFGPPLRYTVIKEQLEDDVPYE 1280

[Close]

BLAST of Cla002115 vs. TrEMBL
Match: A0A067FY02_CITSI (Uncharacterized protein (Fragment) OS=Citrus sinensis GN=CISIN_1g0072032mg PE=4 SV=1)

HSP 1 Score: 250.4 bits (638), Expect = 1.8e-63
Identity = 125/151 (82.78%), Postives = 145/151 (96.03%), Query Frame = 1


Query: 27  GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
           GAIFIV L++TSSLWSS II++VL MIVIDL+GVMA+L IQLNAVSVVN++MSIGIAVEF
Sbjct: 296 GAIFIVCLLMTSSLWSSAIILVVLVMIVIDLLGVMAILGIQLNAVSVVNLIMSIGIAVEF 355

Query: 87  CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
           C+H+VHAFLVS G+R+QR+Q+ALST+GASVFSGITLTKLVGVIVLCFA+SEIFVVYYFQM
Sbjct: 356 CVHIVHAFLVSHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQM 415

Query: 147 YLALVIIGFLHGLVFLPVILSMIGPPSRYLV 178
           YLALVIIGFLHGLVFLPVILS+ GPPSR+++
Sbjct: 416 YLALVIIGFLHGLVFLPVILSLFGPPSRHII 446

[Close]

BLAST of Cla002115 vs. TrEMBL
Match: V4S5N4_9ROSI (Uncharacterized protein (Fragment) OS=Citrus clementina GN=CICLE_v100301201mg PE=4 SV=1)

HSP 1 Score: 250.4 bits (638), Expect = 1.8e-63
Identity = 125/151 (82.78%), Postives = 145/151 (96.03%), Query Frame = 1


Query: 27  GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
           GAIFIV L++TSSLWSS II++VL MIVIDL+GVMA+L IQLNAVSVVN++MSIGIAVEF
Sbjct: 625 GAIFIVCLLMTSSLWSSAIILVVLVMIVIDLLGVMAILGIQLNAVSVVNLIMSIGIAVEF 684

Query: 87  CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
           C+H+VHAFLVS G+R+QR+Q+ALST+GASVFSGITLTKLVGVIVLCFA+SEIFVVYYFQM
Sbjct: 685 CVHIVHAFLVSHGNRNQRSQKALSTMGASVFSGITLTKLVGVIVLCFARSEIFVVYYFQM 744

Query: 147 YLALVIIGFLHGLVFLPVILSMIGPPSRYLV 178
           YLALVIIGFLHGLVFLPVILS+ GPPSR+++
Sbjct: 745 YLALVIIGFLHGLVFLPVILSLFGPPSRHII 775

[Close]

BLAST of Cla002115 vs. NCBI nr
Match: gi|778712664|ref|XP_011656917.1| (PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis sativus])

HSP 1 Score: 300.4 bits (768), Expect = 2.2e-78
Identity = 156/164 (95.12%), Postives = 161/164 (98.17%), Query Frame = 1


Query: 27   GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
            GAIFIVSLVITSSLWSSG+IILVLAMIVIDL+GVMAVLKIQLNAVSVVNILMSIGIAVEF
Sbjct: 1139 GAIFIVSLVITSSLWSSGMIILVLAMIVIDLLGVMAVLKIQLNAVSVVNILMSIGIAVEF 1198

Query: 87   CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
            C+HLVHAF VSCGDRSQRAQEALST+GASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM
Sbjct: 1199 CVHLVHAFSVSCGDRSQRAQEALSTIGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 1258

Query: 147  YLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS 191
            YLALVIIGFLHGLVFLPVILSMIGPPSRYL+ DDAP ETELLVS
Sbjct: 1259 YLALVIIGFLHGLVFLPVILSMIGPPSRYLISDDAPMETELLVS 1302

[Close]

BLAST of Cla002115 vs. NCBI nr
Match: gi|700191466|gb|KGN46670.1| (hypothetical protein Csa_6G120400 [Cucumis sativus])

HSP 1 Score: 300.4 bits (768), Expect = 2.2e-78
Identity = 156/164 (95.12%), Postives = 161/164 (98.17%), Query Frame = 1


Query: 27  GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
           GAIFIVSLVITSSLWSSG+IILVLAMIVIDL+GVMAVLKIQLNAVSVVNILMSIGIAVEF
Sbjct: 32  GAIFIVSLVITSSLWSSGMIILVLAMIVIDLLGVMAVLKIQLNAVSVVNILMSIGIAVEF 91

Query: 87  CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
           C+HLVHAF VSCGDRSQRAQEALST+GASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM
Sbjct: 92  CVHLVHAFSVSCGDRSQRAQEALSTIGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 151

Query: 147 YLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS 191
           YLALVIIGFLHGLVFLPVILSMIGPPSRYL+ DDAP ETELLVS
Sbjct: 152 YLALVIIGFLHGLVFLPVILSMIGPPSRYLISDDAPMETELLVS 195

[Close]

BLAST of Cla002115 vs. NCBI nr
Match: gi|659094693|ref|XP_008448194.1| (PREDICTED: Niemann-Pick C1 protein-like isoform X2 [Cucumis melo])

HSP 1 Score: 297.4 bits (760), Expect = 1.8e-77
Identity = 152/164 (92.68%), Postives = 161/164 (98.17%), Query Frame = 1


Query: 27   GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
            GAIFIVSLVITSSLW SG+IILVLAMIVIDL+GVMA+LKIQLNAVSVVNILMSIGIAVEF
Sbjct: 1138 GAIFIVSLVITSSLWCSGMIILVLAMIVIDLLGVMAILKIQLNAVSVVNILMSIGIAVEF 1197

Query: 87   CIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKSEIFVVYYFQM 146
            C+HLVHAF VSCGDR+QRAQEALST+GASVFSGITLTKLVGV+VLCFAKSEIFVVYYFQM
Sbjct: 1198 CVHLVHAFSVSCGDRNQRAQEALSTIGASVFSGITLTKLVGVVVLCFAKSEIFVVYYFQM 1257

Query: 147  YLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS 191
            YLALVIIGFLHGLVFLPVILSMIGPPSRYL++DDAP ETELLVS
Sbjct: 1258 YLALVIIGFLHGLVFLPVILSMIGPPSRYLIKDDAPVETELLVS 1301

[Close]

BLAST of Cla002115 vs. NCBI nr
Match: gi|659094691|ref|XP_008448193.1| (PREDICTED: Niemann-Pick C1 protein-like isoform X1 [Cucumis melo])

HSP 1 Score: 289.7 bits (740), Expect = 3.8e-75
Identity = 152/174 (87.36%), Postives = 161/174 (92.53%), Query Frame = 1


Query: 27   GAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVNILMSIGIAVEF 86
            GAIFIVSLVITSSLW SG+IILVLAMIVIDL+GVMA+LKIQLNAVSVVNILMSIGIAVEF
Sbjct: 1138 GAIFIVSLVITSSLWCSGMIILVLAMIVIDLLGVMAILKIQLNAVSVVNILMSIGIAVEF 1197

Query: 87   CIHLVHAF----------LVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAKS 146
            C+HLVHAF           VSCGDR+QRAQEALST+GASVFSGITLTKLVGV+VLCFAKS
Sbjct: 1198 CVHLVHAFSVSTNPTHFITVSCGDRNQRAQEALSTIGASVFSGITLTKLVGVVVLCFAKS 1257

Query: 147  EIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYLVEDDAPTETELLVS 191
            EIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYL++DDAP ETELLVS
Sbjct: 1258 EIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYLIKDDAPVETELLVS 1311

[Close]

BLAST of Cla002115 vs. NCBI nr
Match: gi|542316664|gb|AGV40494.1| (hypothetical protein [Phaseolus vulgaris])

HSP 1 Score: 255.0 bits (650), Expect = 1.0e-64
Identity = 131/172 (76.16%), Postives = 149/172 (86.63%), Query Frame = 1


Query: 16  ISLRIFCDAIAGAIFIVSLVITSSLWSSGIIILVLAMIVIDLMGVMAVLKIQLNAVSVVN 75
           I++ I    IAGAIF+V LVITSSLWSS I++LVL MI++DLMGVMA+L IQLNAVSVVN
Sbjct: 248 INITIALGDIAGAIFVVCLVITSSLWSSAIVLLVLVMIILDLMGVMAILGIQLNAVSVVN 307

Query: 76  ILMSIGIAVEFCIHLVHAFLVSCGDRSQRAQEALSTVGASVFSGITLTKLVGVIVLCFAK 135
           ++MS+GIAVEFC+H+VHAF VS GDRSQRA+ AL TVGASVFSGITLTKLVGVIVLCF+ 
Sbjct: 308 LVMSLGIAVEFCVHIVHAFTVSLGDRSQRAKTALCTVGASVFSGITLTKLVGVIVLCFST 367

Query: 136 SEIFVVYYFQMYLALVIIGFLHGLVFLPVILSMIGPPSRYLV-----EDDAP 183
           SE+FVVYYFQMYLALVIIGFLHGLVFLPV+LS+ GPP RY V     EDD P
Sbjct: 368 SELFVVYYFQMYLALVIIGFLHGLVFLPVVLSLFGPPLRYTVIKEQLEDDVP 419

The following BLAST results are available for this feature:

BLAST of Cla002115 vs. Swiss-Prot


Match Name	E-value	Identity	Description
NPC1_HUMAN	1.4e-40	56.46	Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2	[more]
NPC1_MOUSE	1.8e-40	56.46	Niemann-Pick C1 protein OS=Mus musculus GN=Npc1 PE=1 SV=2	[more]
NPC1_PIG	6.8e-40	55.78	Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=2 SV=1	[more]
NPC1_YEAST	1.8e-32	44.44	Niemann-Pick type C-related protein 1 OS=Saccharomyces cerevisiae (strain ATCC 2...	[more]
PTC1_HUMAN	8.6e-27	40.51	Protein patched homolog 1 OS=Homo sapiens GN=PTCH1 PE=1 SV=2	[more]

BLAST of Cla002115 vs. TrEMBL


Match Name	E-value	Identity	Description
A0A0A0KAC3_CUCSA	1.5e-78	95.12	Uncharacterized protein OS=Cucumis sativus GN=Csa_6G120400 PE=4 SV=1	[more]
T2D239_PHAVU	7.3e-65	76.16	Uncharacterized protein OS=Phaseolus vulgaris PE=4 SV=1	[more]
V7B9Q8_PHAVU	1.0e-63	78.53	Uncharacterized protein OS=Phaseolus vulgaris GN=PHAVU_008G291900g PE=4 SV=1	[more]
A0A067FY02_CITSI	1.8e-63	82.78	Uncharacterized protein (Fragment) OS=Citrus sinensis GN=CISIN_1g0072032mg PE=4 ...	[more]
V4S5N4_9ROSI	1.8e-63	82.78	Uncharacterized protein (Fragment) OS=Citrus clementina GN=CICLE_v100301201mg PE...	[more]

BLAST of Cla002115 vs. NCBI nr


Match Name	E-value	Identity	Description
gi\|778712664\|ref\|XP_011656917.1\|	2.2e-78	95.12	PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis sativus]	[more]
gi\|700191466\|gb\|KGN46670.1\|	2.2e-78	95.12	hypothetical protein Csa_6G120400 [Cucumis sativus]	[more]
gi\|659094693\|ref\|XP_008448194.1\|	1.8e-77	92.68	PREDICTED: Niemann-Pick C1 protein-like isoform X2 [Cucumis melo]	[more]
gi\|659094691\|ref\|XP_008448193.1\|	3.8e-75	87.36	PREDICTED: Niemann-Pick C1 protein-like isoform X1 [Cucumis melo]	[more]
gi\|542316664\|gb\|AGV40494.1\|	1.0e-64	76.16	hypothetical protein [Phaseolus vulgaris]	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **INTERPRO**
Term	Definition
IPR003392	Ptc/Disp

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0030301	cholesterol transport
biological_process	GO:0007165	signal transduction
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0008158	hedgehog receptor activity

Unigene

This gene is associated with the following unigenes:


Unigene Name	Analysis Name	Sequence type in Unigene
WMU37664	watermelon unigene v2 vs TrEMBL	transcribed_cluster

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Cla002115	Cla002115.1	mRNA

The following transcribed_cluster feature(s) are associated with this gene:


Feature Name	Unique Name	Type
WMU37664	WMU37664	transcribed_cluster

InterPro

Analysis Name: InterPro Annotations of watermelon (97103)
Date Performed: 2016-09-28


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003392	Protein patched/dispatched	PFAM	PF02460	Patched	coord: 28..169 score: 1.3
None	No IPR available	GENE3D	G3DSA:1.20.1640.10		coord: 27..173 score: 1.1
None	No IPR available	PANTHER	PTHR10796	PATCHED-RELATED	coord: 27..177 score: 1.7E
None	No IPR available	PANTHER	PTHR10796:SF117	PATCHED FAMILY PROTEIN	coord: 27..177 score: 1.7E
None	No IPR available	unknown	SSF82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 26..170 score: 9.02

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
Cla002115	ClCG02G009930	Watermelon (Charleston Gray)	wcgwmB216

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
Cla002115	Watermelon (97103) v1	wmwmB005