Carg12895 (gene) Silver-seed gourd | Cucurbit Genomics Database (CuGenDB)

Overview


Name	Carg12895
Type	gene
Organism	Cucurbita argyrosperma (Silver-seed gourd)
Description	Mevalonate kinase
Location	Cucurbita_argyrosperma_scaffold_043 : 1026531 .. 1030707 (+)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: polypeptideexonCDSthree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGGAAGTTAAAGCCAGAGCTCCTGGGAAAATCATACTCGCCGGTGAACACGCGGTCGTCCATGGTTCCACCGCCGTCGCTGCTTCCGTCAACCTCTACACTACAGCTTCAGTTCGATTGCCATGTTCTTCAGGTGCTCATTCTATCTCTCTCACTCTCATTTGAGGTTGACTTTTATTTGGGTGTTTGAAACTGAAGCGTATGATATGGAAGGTGAATTTGAAGAGTATTAGTTTCCTTCATGTGCCTGTTCTAATTGCTTGATTCCCATTTGAATTTTGATGATATTTCTATGTCATTTTTATGGGTTGTTATTAACGCTTCCTTTTGTAGATATTACATCTCGGTTAGGTATCATATTTGACCCTCTGGTATGATATTTAATCTTCCATTAAGGTTTGCTATAGGTATCGTATTCGATCCTTGTATGATATTCAATTTTCTATTACAATTTATCATAGGTATCATATTTGACATTTGTATGATATTTAGTCTTCGATTACGATTTACCATAGGTATCATATTTAACCTTGTATGATATTTAGTCTTCCATTTCGGTTTACCATAGACGTCATATTTCACCTTGTATGATATTTAGCCTTCCATTACGGTTTACCATATGTATCATATTTGATCCCTGTTTGATATTTAGTCTTCCATTACAGTTTACCATAGGTATCGTATTTGACCCTTGTATGATATTTATCCTTCCATACCATAGGTATCGTAAAAGACAAATATTTTGTATCCATTTATTGTTGTTTTCATTTCCTTGGTAACTTTCACCACCGTTTAAGTACGGTGATTTTAGCAAATATTCTCACCCTCGAGTCTTTACCCACACTTTTCCTCATCAAATTACATTTCTTATCAGACAAGGATGATATTGTGAAACTCCAACTGAAGGACCTAGCACTTGAGTTTGCATGGCCAGTTAGTAGAATCAAGGAGGCTTTGGGTGGATTCGTTGGTCCCATCTCGACACCCACATCATGCCCTGCTGAGTGCTTGAAAGCAATTGCATCTCTTGTTGAGTATCAAAACATTCCGGAGGCTAAAATTAAGCTTGCCTCTGGAGTGTCAGCATTCCTTTGGCTCTATTCTTCCATTCTAAGGTTTGTATTTCATTCATGAAAGGTTTGAAAGATTTTAACTTGTTCATCCTCCATTTCACTTATTATGCTCTCTTGTCTTTCAGATTTGTGCCTGTTGATGTAGCCATCACGTCTGAGCTTCCTCTTGGATCAGGCTTGGGCTCATCTGCTGCATTTTGTGTTGCCATTTCAGCTGCTCTGCTTGCTTTATCAGGCTCTGTGAATGTCGATCAGGAGCAGTGTGGATGGATGGTATGTAAAGAAGATGAGCTAGTTTTGTTGAACAAGTGGGCCTTTGAGGGTGAAAAGATAATCCATGGAAAACCTTCTGGAATTGACAATACTGTGAGCACATATGGTATGCAAAATCCATTTTCTTCTTATCGTAATCCTCTCACTTTGAGATCCCACGTCGGTTGCAGAGGGAAACGAAGTATTCCTTGTAAGCGTGTGGAAATCTCTCTCTAGTAGATGCGTTTTAAAACCGTGAAGTTGACGGCGATGCGTAACGGGTCAAAGCAGACAATATCTGCTAGCGGTGGGCTTGGGCCGTTACAAATGACATTAAAGTCAAACACCGAGCGGTGTGCTAGCGAGGACGCTGGACCCTCAAGGGGGGTGGGGATTGTAAGATCTCATATCGGTTGGAGAGGCGAACGAAGCATTCCTTAGAAGGGTGTGGAAACCTCTCCCTAGTAGATGCGTTTTAAAACCGTGAGGCTGACGGCGATATGTAACGGGTCAAAGTAAATAATATCTGCTAGTGGTAAGCTTGGACTATTACAAATGGTATCAGAGCTAGACATAGGGCGATGTGCCAGAGAGGACGCTGGACCCACGAGGGGGGTGAATTGTGAGATCTCATATCGATTGGAAGGGGGAACGAAGCATTCCTTATAAGGGTGTGGAAACCTCTCCCTAATGGACGCATTTTAAAATCGTGAGGCTGATGACGAAACGTAACGGGTCAAAGCGGACAATATTTGCCAACGGTGGGCTTGGGCTGTTACAAATGGTATTAGAGTTAGAAACTAGACGGTGTGCCAGCGAGAACGCTGGAACCTCAAGAGAGGTGGATTGTGGGATCCCAATCGGTTGGAGAGGGGAACAAACCATTTATAAGGGTGTGAAAACCTCTTCCTAGCAAATGCGTTTTAAGTCAAATCAGACAATATCTGCTAGTAGTGGGCTTGGACTATTACAAATGATATGAGAGCTAGATACCAGGTGGTGTGCCAGCGAGGATGTTGGACCGCTAAAGGAAGTGGATTGTGAGATCCCACATCGGTTGGAGAGTGGAATGAAGCATTCCTTATAAAGGTGTGGAAACCTCTCTCTAGTAGACGCGTTTTAAACCGGTAAGGCTGACGGCGATACGTAACGGGTCAAAGCGGACAATATCTATTAGCGGTGGGATTGGGGCTATTACATTAACATAAATTTGAACTCAATTTCAAACCTCAATTCGTATCGATGTTCTTGTGTATCTAATACAAGAAAATCCCATGTATCAGGCAGCATGATCAAGTTCAGGTCAGGCAGTTTGGATCTCATTAAATCCAATATGCCATTGAAAATGCTTGTTACAAACACAAAGGTTGGAAGAAACACAAAGGCTTTAGTGGCTGGTGTTTCAGAAAGGGCCATCAGACATCCTGATGCAATGAGCTCTGTGTTCAATGCTGTCGATTCTATCAGCAAGGAGTTATCAATCCTTCTTCAGTCATTAGCTCATGACGACATGTCCCTAACTGAGAAGGAAGAACAGTTAGCAGAGTTGATGGAAATGAATCAAGGCTTACTTCAGTGTATGGGGGTAAGCCATGGTTCTATCGAAACCATCCTCCGGACGACGTCGAAATACGAGCTAGTTTCCAAATTGACAGGAGCTGGAGGTGGAGGCTGTGTTCTTACGCTGTTGCCTAACTGTATCCTTTTCCTGTCATGGAATCTTATGCCTTTGACTCTTCATATGCTCTTACTTCTATCGTTCATTGGTTCGTGGTTAATCCATATTTTCCCTTCCTATCTAACGATTGCCATGATACCCTTATGATCAATTAATGGGACAAAGTCGGAAAATGTTCTTGTAAGATCCTACATCGGTTGGGGTTCGTTGAGCCTTAAAGGGGAGTGGATTGTGAGATCTCATATCGATTGGAGAGTAGAATGAAGCATTCTTTATAAGGGTGTTGAAACCTCTCCCTAGAAGACACATTTTGAAACCTTGAGAGAAACCCCAAAAGAAAAAATTCAAAAAAGACAATATCTATTAACGGTGGGCTTGGGTTGATACAGTTATTGCTCTATTATTAGCTCAGATAGCCATCGTTTCTGGCGTTTATGTCTCCTTTTAATGACTCCCTTAAGAATTTACCTAGTCGAGTAATAATGGGAATGGGAAGGGAGAAGTTTCTAAATATTATCAGTTTTCTAACTGATACGTTTTCTTTAGATGCAATGACAGCATATTCTTTTATGCATTTTCTTAACTATGTGGAACAGTGCTTTCAGGGACCATTGTTGATGAAGTAATTGCAGAGCTTGAGTCATGTGGATTTGAATGCTTCATTGCTGGGATTGGAGGAAAAGGGGCCGAGATCTCGTTCCATGATTTAGCCTGAAAAATTTTCAAGCGATTCTTTGAACGAAACGAACTCTTTTCCTTTTGTTTCTTTCCTTTCACGAAGTCTAATAAGCTCTCATTACTTCAGACATGTCACTTGAAAAAGATTCCTTAAAATTATGGTTCACTTTCAGTAGACGTATTGAGTTGGTCTCGCTTTGATATTCACACACCTTAACAGTATATTTATCATTTGCGAGAGATAGCCGACGTGCAAAATAGAGAAAAGCAGTGCACATCAGTATGGTACTTACCCCTCTGGCTCAGGTTAAATATAACAAGTTTACTTGACCTCAGTGGGTTATAATAGTGTATTTATAGGAGAATTGACAGAAAGTTAACTTTGAGCTCTCATAGACCCTAATGAATTTAGTCTTTTAGTAAATGATCAACTCGATGATTAGCCCGTCTTCGCTCGATTTCGTCAAGCACAATTTTACTCAAAGAAGATGAAATA

mRNA sequence

ATGGAAGTTAAAGCCAGAGCTCCTGGGAAAATCATACTCGCCGGTGAACACGCGGTCGTCCATGGTTCCACCGCCGTCGCTGCTTCCGTCAACCTCTACACTACAGCTTCAGTTCGATTGCCATGTTCTTCAGTTAGTAGAATCAAGGAGGCTTTGGGTGGATTCGTTGGTCCCATCTCGACACCCACATCATGCCCTGCTGAGTGCTTGAAAGCAATTGCATCTCTTGTTGAGTATCAAAACATTCCGGAGGCTAAAATTAAGCTTGCCTCTGGAGTGTCAGCATTCCTTTGGCTCTATTCTTCCATTCTAAGATTTGTGCCTGTTGATGTAGCCATCACGTCTGAGCTTCCTCTTGGATCAGGCTTGGGCTCATCTGCTGCATTTTGTGTTGCCATTTCAGCTGCTCTGCTTGCTTTATCAGGCTCTGTGAATGTCGATCAGGAGCAGTGTGGATGGATGGTATGTAAAGAAGATGAGCTAGTTTTGTTGAACAAGTGGGCCTTTGAGGGCAGTTTGGATCTCATTAAATCCAATATGCCATTGAAAATGCTTGTTACAAACACAAAGGTTGGAAGAAACACAAAGGCTTTAGTGGCTGGTGTTTCAGAAAGGGCCATCAGACATCCTGATGCAATGAGCTCTGTGTTCAATGCTGTCGATTCTATCAGCAAGGAGTTATCAATCCTTCTTCAGTCATTAGCTCATGACGACATGTCCCTAACTGAGAAGGAAGAACAGTTAGCAGAGTTGATGGAAATGAATCAAGGCTTACTTCAGTGTATGGGGGTAAGCCATGGTTCTATCGAAACCATCCTCCGGACGACGTCGAAATACGAGCTAGTTTCCAAATTGACAGGAGCTGGAGGTGGAGGCTGTGTTCTTACGCTGTTGCCTAACTTGCTTTCAGGGACCATTGTTGATGAAGTAATTGCAGAGCTTGAGTCATGTGGATTTGAATGCTTCATTGCTGGGATTGGAGGAAAAGGGGCCGAGATCTCGTTCCATGATTTAGCCTGAAAAATTTTCAAGCGATTCTTTGAACGAAACGAACTCTTTTCCTTTTGTTTCTTTCCTTTCACGAAGTCTAATAAGCTCTCATTACTTCAGACATGTCACTTGAAAAAGATTCCTTAAAATTATGGTTCACTTTCAGTAGACGTATTGAGTTGGTCTCGCTTTGATATTCACACACCTTAACAGTATATTTATCATTTGCGAGAGATAGCCGACGTGCAAAATAGAGAAAAGCAGTGCACATCAGTATGGTACTTACCCCTCTGGCTCAGGTTAAATATAACAAGTTTACTTGACCTCAGTGGGTTATAATAGTGTATTTATAGGAGAATTGACAGAAAGTTAACTTTGAGCTCTCATAGACCCTAATGAATTTAGTCTTTTAGTAAATGATCAACTCGATGATTAGCCCGTCTTCGCTCGATTTCGTCAAGCACAATTTTACTCAAAGAAGATGAAATA

Coding sequence (CDS)

ATGGAAGTTAAAGCCAGAGCTCCTGGGAAAATCATACTCGCCGGTGAACACGCGGTCGTCCATGGTTCCACCGCCGTCGCTGCTTCCGTCAACCTCTACACTACAGCTTCAGTTCGATTGCCATGTTCTTCAGTTAGTAGAATCAAGGAGGCTTTGGGTGGATTCGTTGGTCCCATCTCGACACCCACATCATGCCCTGCTGAGTGCTTGAAAGCAATTGCATCTCTTGTTGAGTATCAAAACATTCCGGAGGCTAAAATTAAGCTTGCCTCTGGAGTGTCAGCATTCCTTTGGCTCTATTCTTCCATTCTAAGATTTGTGCCTGTTGATGTAGCCATCACGTCTGAGCTTCCTCTTGGATCAGGCTTGGGCTCATCTGCTGCATTTTGTGTTGCCATTTCAGCTGCTCTGCTTGCTTTATCAGGCTCTGTGAATGTCGATCAGGAGCAGTGTGGATGGATGGTATGTAAAGAAGATGAGCTAGTTTTGTTGAACAAGTGGGCCTTTGAGGGCAGTTTGGATCTCATTAAATCCAATATGCCATTGAAAATGCTTGTTACAAACACAAAGGTTGGAAGAAACACAAAGGCTTTAGTGGCTGGTGTTTCAGAAAGGGCCATCAGACATCCTGATGCAATGAGCTCTGTGTTCAATGCTGTCGATTCTATCAGCAAGGAGTTATCAATCCTTCTTCAGTCATTAGCTCATGACGACATGTCCCTAACTGAGAAGGAAGAACAGTTAGCAGAGTTGATGGAAATGAATCAAGGCTTACTTCAGTGTATGGGGGTAAGCCATGGTTCTATCGAAACCATCCTCCGGACGACGTCGAAATACGAGCTAGTTTCCAAATTGACAGGAGCTGGAGGTGGAGGCTGTGTTCTTACGCTGTTGCCTAACTTGCTTTCAGGGACCATTGTTGATGAAGTAATTGCAGAGCTTGAGTCATGTGGATTTGAATGCTTCATTGCTGGGATTGGAGGAAAAGGGGCCGAGATCTCGTTCCATGATTTAGCCTGA

Protein sequence

MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSSVSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLYSSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDELVLLNKWAFEGSLDLIKSNMPLKMLVTNTKVGRNTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELMEMNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAELESCGFECFIAGIGGKGAEISFHDLA

Homology

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BLAST of Carg12895 vs. NCBI nr
Match: XP_023545825.1 (mevalonate kinase-like isoform X2 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 614.8 bits (1584), Expect = 1.8e-172
Identity = 337/386 (87.31%), Postives = 337/386 (87.31%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSSDEDDIVKLQLKDLALE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY
Sbjct: 61  FAWPVSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQE CGWMVCKEDE
Sbjct: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEHCGWMVCKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           LVLLNKWAFE                           GSLDLIKSNMPLKMLVTNTKVGR
Sbjct: 181 LVLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFKSGSLDLIKSNMPLKMLVTNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQS AHDDMSLTEKEEQLAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQS-AHDDMSLTEKEEQLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE
Sbjct: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 360

[Close]

BLAST of Carg12895 vs. NCBI nr
Match: XP_022946758.1 (mevalonate kinase-like [Cucurbita moschata])

HSP 1 Score: 608.6 bits (1568), Expect = 1.3e-170
Identity = 330/385 (85.71%), Postives = 335/385 (87.01%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSSDKDDIVKLQLKDLALE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY
Sbjct: 61  FAWPVSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE
Sbjct: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           LVLLNKWAFE                           GSLDLIKSNMPL+MLVTNTKVGR
Sbjct: 181 LVLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFRSGSLDLIKSNMPLEMLVTNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQS AHDDMSLT+KEEQLAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSSAHDDMSLTQKEEQLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 339
           MNQGLLQCMG+SHGSIET+L+TTSKY LVSKLTGAG GGCVLTLLPNLLSGTIVDEVIAE
Sbjct: 301 MNQGLLQCMGISHGSIETVLQTTSKYGLVSKLTGAGAGGCVLTLLPNLLSGTIVDEVIAE 360

[Close]

BLAST of Carg12895 vs. NCBI nr
Match: XP_022999117.1 (mevalonate kinase-like [Cucurbita maxima])

HSP 1 Score: 595.9 bits (1535), Expect = 8.6e-167
Identity = 329/386 (85.23%), Postives = 331/386 (85.75%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLP SS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPSSSDKDDIVKLQLKDLALE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRIKEALGGFVGPISTPTSCPAECLK IASLVEYQNIPEAKIKLASGVSAFLWLY
Sbjct: 61  FAWPVSRIKEALGGFVGPISTPTSCPAECLKTIASLVEYQNIPEAKIKLASGVSAFLWLY 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQ  CGWMVC EDE
Sbjct: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQGHCGWMVC-EDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           LVLLNKWAFE                           GSLDLIKSNMPLKMLVTNTKVGR
Sbjct: 181 LVLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFRSGSLDLIKSNMPLKMLVTNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAM SVFNAVDSISKELSILLQS AHDDMSLTEKEEQLAEL E
Sbjct: 241 NTKALVAGVSERAIRHPDAMISVFNAVDSISKELSILLQSSAHDDMSLTEKEEQLAELTE 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSHGSIET+LRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE
Sbjct: 301 MNQGLLQCMGVSHGSIETVLRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 360

[Close]

BLAST of Carg12895 vs. NCBI nr
Match: XP_023545824.1 (mevalonate kinase-like isoform X1 [Cucurbita pepo subsp. pepo])

HSP 1 Score: 537.3 bits (1383), Expect = 3.6e-149
Identity = 298/349 (85.39%), Postives = 299/349 (85.67%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSSDEDDIVKLQLKDLALE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY
Sbjct: 61  FAWPVSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQE CGWMVCKEDE
Sbjct: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEHCGWMVCKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           LVLLNKWAFE                           GSLDLIKSNMPLKMLVTNTKVGR
Sbjct: 181 LVLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFKSGSLDLIKSNMPLKMLVTNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQS AHDDMSLTEKEEQLAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQS-AHDDMSLTEKEEQLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLL 303
           MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPN +
Sbjct: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNCI 348

[Close]

BLAST of Carg12895 vs. NCBI nr
Match: XP_004139185.1 (PREDICTED: mevalonate kinase [Cucumis sativus] >KGN60892.1 hypothetical protein Csa_2G021630 [Cucumis sativus])

HSP 1 Score: 532.7 bits (1371), Expect = 9.0e-148
Identity = 294/386 (76.17%), Postives = 315/386 (81.61%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASV+LYTT SVRLP SS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVDLYTTVSVRLPSSSDENEIVKLQLKDLELE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRI+EALG FVG IS+PT+CPAECLK+IASLVE QNIPE KI LASGV+AFLWL 
Sbjct: 61  FSWPVSRIREALGVFVGAISSPTTCPAECLKSIASLVEDQNIPEVKIGLASGVAAFLWLC 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSIL FVPV+VAITSELPLGSGLGSSAAFCVA+SAALLALSGSVNVD+E  GWMV KEDE
Sbjct: 121 SSILGFVPVEVAITSELPLGSGLGSSAAFCVALSAALLALSGSVNVDREHHGWMVHKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           L LLNKWAFE                           G+L LIKSNMPLKML+TNTKVGR
Sbjct: 181 LDLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFRSGNLTLIKSNMPLKMLITNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAM SVFNAV+SIS ELSIL+QS  HDD+SLTE EE+LAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMKSVFNAVNSISDELSILIQSPIHDDVSLTENEEKLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSH SIET+LRT+ KY+L+SKLTGAGGGGCVLTLLPNLLSG +VDEVIAE
Sbjct: 301 MNQGLLQCMGVSHASIETVLRTSLKYKLISKLTGAGGGGCVLTLLPNLLSGKVVDEVIAE 360

[Close]

BLAST of Carg12895 vs. TAIR10
Match: AT5G27450.1 (mevalonate kinase)

HSP 1 Score: 374.4 bits (960), Expect = 7.4e-104
Identity = 217/385 (56.36%), Postives = 265/385 (68.83%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCS----------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAA+++LYT  ++R P                   
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  ----SVSRIKEALGGFVGPI--STPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFL 120
               S++RIKEA+      +  STP SC  E LK+IA LVE QN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCK 180
           WLY+ I+ F P  V I SELP GSGLGSSAA CVA++AALLA   S++      GW    
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EDELVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTK 240
           E  L LLNKWAFE                           G +  ++SNMPL+ML+TNT+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAE 300
           VGRNTKALV+GVS+RA+RHPDAM SVFNAVDSISKEL+ ++QS   D+ S+TEKEE++ E
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQS--KDETSVTEKEERIKE 300

Query: 301 LMEMNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEV 336
           LMEMNQGLL  MGVSH SIE ++ TT K++LVSKLTGAGGGGCVLTLLP   +GT+VD+V
Sbjct: 301 LMEMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLP---TGTVVDKV 360

[Close]

BLAST of Carg12895 vs. Swiss-Prot
Match: sp|P46086|KIME_ARATH (Mevalonate kinase OS=Arabidopsis thaliana OX=3702 GN=At5g27450 PE=2 SV=1)

HSP 1 Score: 374.4 bits (960), Expect = 1.3e-102
Identity = 217/385 (56.36%), Postives = 265/385 (68.83%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCS----------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAA+++LYT  ++R P                   
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAAAIDLYTYVTLRFPLPSAENNDRLTLQLKDISL 60

Query: 61  ----SVSRIKEALGGFVGPI--STPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFL 120
               S++RIKEA+      +  STP SC  E LK+IA LVE QN+P+ K+ L+SG+S FL
Sbjct: 61  EFSWSLARIKEAIPYDSSTLCRSTPASCSEETLKSIAVLVEEQNLPKEKMWLSSGISTFL 120

Query: 121 WLYSSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCK 180
           WLY+ I+ F P  V I SELP GSGLGSSAA CVA++AALLA   S++      GW    
Sbjct: 121 WLYTRIIGFNPATVVINSELPYGSGLGSSAALCVALTAALLA--SSISEKTRGNGWSSLD 180

Query: 181 EDELVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTK 240
           E  L LLNKWAFE                           G +  ++SNMPL+ML+TNT+
Sbjct: 181 ETNLELLNKWAFEGEKIIHGKPSGIDNTVSAYGNMIKFCSGEITRLQSNMPLRMLITNTR 240

Query: 241 VGRNTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAE 300
           VGRNTKALV+GVS+RA+RHPDAM SVFNAVDSISKEL+ ++QS   D+ S+TEKEE++ E
Sbjct: 241 VGRNTKALVSGVSQRAVRHPDAMKSVFNAVDSISKELAAIIQS--KDETSVTEKEERIKE 300

Query: 301 LMEMNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEV 336
           LMEMNQGLL  MGVSH SIE ++ TT K++LVSKLTGAGGGGCVLTLLP   +GT+VD+V
Sbjct: 301 LMEMNQGLLLSMGVSHSSIEAVILTTVKHKLVSKLTGAGGGGCVLTLLP---TGTVVDKV 360

[Close]

BLAST of Carg12895 vs. Swiss-Prot
Match: sp|Q03426|KIME_HUMAN (Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1)

HSP 1 Score: 184.9 bits (468), Expect = 1.5e-45
Identity = 141/378 (37.30%), Postives = 198/378 (52.38%), Query Frame = 0


Query: 7   APGKIILAGEHAVVHGSTAVAASVNLYT----------TASVRLP------CSSVSRIKE 66
           APGK+IL GEHAVVHG  A+A S+NL T             + LP         V+R++ 
Sbjct: 10  APGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQS 69

Query: 67  ALGGFV--GPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLYSSILR--- 126
               F+  G ++TPTS   E LK +A L +   + E   +LA  V AFL+LY SI R   
Sbjct: 70  LDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTE---RLA--VLAFLYLYLSICRKQR 129

Query: 127 -FVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSV--NVDQEQCGWMVCKEDELV 186
               +D+ + SELP G+GLGSSAA+ V ++AALL +   +   +    C     KED L 
Sbjct: 130 ALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKED-LE 189

Query: 187 LLNKWAF---------------------------EGSLDLIKSNMPLKMLVTNTKVGRNT 246
           L+NKWAF                           +G +  +K +  L++L+TNTKV RNT
Sbjct: 190 LINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNT 249

Query: 247 KALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELMEMN 306
           +ALVAGV  R ++ P+ ++ +  ++D+IS E   +L  +   +    E+   L EL++MN
Sbjct: 250 RALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMG--EAPAPEQYLVLEELIDMN 309

Query: 307 QGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAELE 334
           Q  L  +GV H S++ + + T    L SKLTGAGGGGC +TLL   L    V+     L 
Sbjct: 310 QHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALT 369

[Close]

BLAST of Carg12895 vs. Swiss-Prot
Match: sp|P17256|KIME_RAT (Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 SV=1)

HSP 1 Score: 176.8 bits (447), Expect = 4.1e-43
Identity = 135/380 (35.53%), Postives = 194/380 (51.05%), Query Frame = 0


Query: 7   APGKIILAGEHAVVHGSTAVAASVNLYT----------TASVRLPCSSVSRIKEAL---- 66
           APGK+IL GEHAVVHG  A+A ++NL T            S+ LP   + ++ +      
Sbjct: 10  APGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVATLQL 69

Query: 67  --GGFV--GPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLYSSILR--- 126
              GF+  G +  PT    E LK +A L       +        + AFL+LY +I R   
Sbjct: 70  LDTGFLEQGDVPAPTLEQLEKLKKVAGLPR-----DCVGNEGLSLLAFLYLYLAICRKQR 129

Query: 127 -FVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWM-VCKEDELVL 186
               +D+ + SELP G+GLGSSAA+ V ++AALL     V    +  G +    E++L  
Sbjct: 130 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 189

Query: 187 LNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGRNTK 246
           +NKWA+E                           G +  +K    L++L+TNTKV R+TK
Sbjct: 190 INKWAYEGERVIHGNPSGVDNSVSTWGGALRYQQGKMSSLKRLPALQILLTNTKVPRSTK 249

Query: 247 ALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELMEMNQ 306
           ALVAGV  R I+ P+ M+ +  ++D+IS E   +L  +A     + E+   L ELM+MNQ
Sbjct: 250 ALVAGVRSRLIKFPEIMAPLLTSIDAISLECERVLGEMA--AAPVPEQYLVLEELMDMNQ 309

Query: 307 GLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAELES 337
             L  +GV H S++ + + T+ + L SKLTGAGGGGC +TLL   L    V+     L  
Sbjct: 310 HHLNALGVGHASLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLERAKVEAAKQALTG 369

[Close]

BLAST of Carg12895 vs. Swiss-Prot
Match: sp|Q9R008|KIME_MOUSE (Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1)

HSP 1 Score: 175.3 bits (443), Expect = 1.2e-42
Identity = 137/385 (35.58%), Postives = 196/385 (50.91%), Query Frame = 0


Query: 7   APGKIILAGEHAVVHGSTAVAASVNLYT----------TASVRLPCSSVSRIKEALGGFV 66
           APGK+IL GEHAVVHG  A+AA++NL T            SV LP   + ++ +   G +
Sbjct: 10  APGKVILHGEHAVVHGKVALAAALNLRTFLLLRPQSNGKVSVNLPNIGIKQVWDV--GML 69

Query: 67  ----------GPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLYSSILR- 126
                     G +S PT    E LK +  L   +   E    L     AFL+LY +I R 
Sbjct: 70  QRLDTSFLEQGDVSVPTLEQLEKLKKMGDLPRDRAGNEGMALL-----AFLYLYLAICRK 129

Query: 127 ---FVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSV-NVDQEQCGWMVCKEDEL 186
                 +D+ + SELP G+GLGSSAA+ V ++AALL     V N  ++        E++L
Sbjct: 130 QRTLPSLDMVVWSELPPGAGLGSSAAYSVCLAAALLTACEEVSNPLKDGVSVSRWPEEDL 189

Query: 187 VLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGRN 246
             +NKWAFE                           G++  +KS   L++L+TNTKV R+
Sbjct: 190 KSINKWAFEGERVIHGNPSGVDNAVSTWGGALRFQQGTMSSLKSLPSLQILLTNTKVPRS 249

Query: 247 TKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELMEM 306
           TKALVA V  R  + P+ ++ +  ++D+IS E   +L  +      + E+   L EL++M
Sbjct: 250 TKALVAAVRSRLTKFPEIVAPLLTSIDAISLECERVLGEMV--AAPVPEQYLVLEELIDM 309

Query: 307 NQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAEL 340
           NQ  L  +GV H S++ + + T+ + L SKLTGAGGGGC +TLL   L    V+     L
Sbjct: 310 NQHHLNALGVGHNSLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLEQATVEAAKQAL 369

[Close]

BLAST of Carg12895 vs. Swiss-Prot
Match: sp|Q5E9T8|KIME_BOVIN (Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1)

HSP 1 Score: 165.2 bits (417), Expect = 1.2e-39
Identity = 132/380 (34.74%), Postives = 188/380 (49.47%), Query Frame = 0


Query: 7   APGKIILAGEHAVVHGSTAVAASVNLYT----------TASVRLPCSSVSRIKEALG--- 66
           APGK+IL GEHAVVHG  A+A ++NL T             + LP   V R  +      
Sbjct: 10  APGKVILHGEHAVVHGKVALAVALNLRTFLRLQPHSNGRVGLNLPNIGVRRAWDVASLQL 69

Query: 67  ---GFV--GPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLYSSIL---R 126
               F+  G  +  T+   E LK +A   +    PE        V AFL+LY SI    R
Sbjct: 70  LDTSFLGHGDSAALTAKHVEKLKEVAGFPKDCVDPE-----HLAVLAFLYLYLSICQSQR 129

Query: 127 FVP-VDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVN---VDQEQCG-WMVCKEDE 186
            +P +D+ + SELP G+GLGSSAA+ V ++AALL     +     D E  G W    E+ 
Sbjct: 130 ALPSLDITVWSELPTGAGLGSSAAYSVCLAAALLTACEEIPNPLKDGEAAGRW---TEEN 189

Query: 187 LVLLNKWAF---------------------------EGSLDLIKSNMPLKMLVTNTKVGR 246
           L L+NKWAF                           +G +  +K    LK+L+ NTKV R
Sbjct: 190 LELINKWAFQGERVIHGNPSGVDNAVSTWGGALRYQQGKISSLKRPPVLKILLINTKVPR 249

Query: 247 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 306
           +TK LVA V  R ++ P+ ++ +  ++D+IS E   +L  +A       E    L EL++
Sbjct: 250 STKVLVANVRSRLLKFPEIVAPLLTSIDAISLECERVLGEMA--AAPTPEHYLTLEELID 309

Query: 307 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 334
           MNQ  L  +GV H S++ + + T+ + L SKLTGAGGGGC +TLL   +    V+     
Sbjct: 310 MNQHHLNALGVGHASLDQLCQVTTAHGLHSKLTGAGGGGCGITLLRPDVERPAVEATKRA 369

[Close]

BLAST of Carg12895 vs. TrEMBL
Match: tr|A0A0A0LJK4|A0A0A0LJK4_CUCSA (Mevalonate kinase OS=Cucumis sativus OX=3659 GN=Csa_2G021630 PE=3 SV=1)

HSP 1 Score: 532.7 bits (1371), Expect = 5.9e-148
Identity = 294/386 (76.17%), Postives = 315/386 (81.61%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASV+LYTT SVRLP SS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVDLYTTVSVRLPSSSDENEIVKLQLKDLELE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSRI+EALG FVG IS+PT+CPAECLK+IASLVE QNIPE KI LASGV+AFLWL 
Sbjct: 61  FSWPVSRIREALGVFVGAISSPTTCPAECLKSIASLVEDQNIPEVKIGLASGVAAFLWLC 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSIL FVPV+VAITSELPLGSGLGSSAAFCVA+SAALLALSGSVNVD+E  GWMV KEDE
Sbjct: 121 SSILGFVPVEVAITSELPLGSGLGSSAAFCVALSAALLALSGSVNVDREHHGWMVHKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           L LLNKWAFE                           G+L LIKSNMPLKML+TNTKVGR
Sbjct: 181 LDLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFRSGNLTLIKSNMPLKMLITNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAM SVFNAV+SIS ELSIL+QS  HDD+SLTE EE+LAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMKSVFNAVNSISDELSILIQSPIHDDVSLTENEEKLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSH SIET+LRT+ KY+L+SKLTGAGGGGCVLTLLPNLLSG +VDEVIAE
Sbjct: 301 MNQGLLQCMGVSHASIETVLRTSLKYKLISKLTGAGGGGCVLTLLPNLLSGKVVDEVIAE 360

[Close]

BLAST of Carg12895 vs. TrEMBL
Match: tr|A0A1S3C084|A0A1S3C084_CUCME (Mevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103495132 PE=3 SV=1)

HSP 1 Score: 531.6 bits (1368), Expect = 1.3e-147
Identity = 293/386 (75.91%), Postives = 316/386 (81.87%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASV+LYTTASVRLP SS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVDLYTTASVRLPSSSDENDIVKLHLKDLELE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               VSR++EALG FVG IS+PT+CPAECLK+IASLVE QNIPEAKI LASGV+AFLWL 
Sbjct: 61  FSWPVSRVREALGVFVGAISSPTTCPAECLKSIASLVEDQNIPEAKIGLASGVAAFLWLC 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSIL FVPV+VAITSELPLGSGLGSSAAFCVA+SAALLALSGSVNVD+E  GWMV KEDE
Sbjct: 121 SSILGFVPVEVAITSELPLGSGLGSSAAFCVALSAALLALSGSVNVDREHHGWMVYKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           L LLNKWAFE                           G+L LIKSNM LKML+TNTKVGR
Sbjct: 181 LDLLNKWAFEGEKIIHGKPSGIDNTVSTYGGMIKFRSGNLTLIKSNMALKMLITNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAM SVFNAV+SIS ELSIL+QS  HD++SLTE EE+LAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMKSVFNAVNSISNELSILIQSPIHDEVSLTENEEKLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSH SIET+LRT+ KY+L+SKLTGAGGGGCVLTLLPNLLSG +VDEVIAE
Sbjct: 301 MNQGLLQCMGVSHASIETVLRTSLKYKLISKLTGAGGGGCVLTLLPNLLSGKVVDEVIAE 360

[Close]

BLAST of Carg12895 vs. TrEMBL
Match: tr|A0A1S3C0R0|A0A1S3C0R0_CUCME (Mevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103495150 PE=3 SV=1)

HSP 1 Score: 498.4 bits (1282), Expect = 1.2e-137
Identity = 279/386 (72.28%), Postives = 303/386 (78.50%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAASV+LYTTASVRLP SS                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVDLYTTASVRLPSSSDENDIVKLQLKDLKLE 60

Query: 61  ----VSRIKEALGGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWLY 120
               +SRI+EALG FVG IS+PT+C AECLK+IASLVE QNIPE  I LASGV+AFLWL 
Sbjct: 61  FSWPLSRIREALGVFVGAISSPTTCLAECLKSIASLVEDQNIPEVNIGLASGVAAFLWLC 120

Query: 121 SSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKEDE 180
           SSIL FVPV+VAITSELPLGSGLGSSAAFCVA+SAALLALSG VNVD+E   WM+ KEDE
Sbjct: 121 SSILGFVPVEVAITSELPLGSGLGSSAAFCVALSAALLALSGFVNVDREHHRWMIYKEDE 180

Query: 181 LVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVGR 240
           L LLNKWAFE                           G+L L KSNMP+KML+TNTKVGR
Sbjct: 181 LDLLNKWAFEGEKIIHGKPSGIDNTVSTYGSMIKFRSGNLTLTKSNMPIKMLITNTKVGR 240

Query: 241 NTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELME 300
           NTKALVAGVSERAIRHPDAM SVFNAV+SI  ELS L+QS  HDD+SLTE EE+LAELME
Sbjct: 241 NTKALVAGVSERAIRHPDAMKSVFNAVNSIGNELSTLIQSPIHDDVSLTENEEKLAELME 300

Query: 301 MNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIAE 340
           MNQGLLQCMGVSH SIET+LRT+ KY+L+ KLT AGGGGCVLTLLPN     +VDEVIAE
Sbjct: 301 MNQGLLQCMGVSHASIETVLRTSLKYKLICKLTEAGGGGCVLTLLPN---WKVVDEVIAE 360

[Close]

BLAST of Carg12895 vs. TrEMBL
Match: tr|A0A2K2AB31|A0A2K2AB31_POPTR (Mevalonate kinase OS=Populus trichocarpa OX=3694 GN=POPTR_005G035300v3 PE=3 SV=1)

HSP 1 Score: 458.4 bits (1178), Expect = 1.4e-125
Identity = 256/383 (66.84%), Postives = 287/383 (74.93%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVR-LPCSS--------------- 60
           MEVKARAPGKIIL+GEHAVVHGSTAVAAS++LYT  S++ LP +                
Sbjct: 1   MEVKARAPGKIILSGEHAVVHGSTAVAASIDLYTYVSIQVLPSTENDDRLTLQLKDMALA 60

Query: 61  ----VSRIKEALGGFVGPI-STPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFLWL 120
               + RIKE+L    GP  STPTSC    +K I +LVE QNIPEAKI LASGV+AFLWL
Sbjct: 61  FSWPIGRIKESLSSLGGPFPSTPTSCSTASMKLILALVEEQNIPEAKISLASGVTAFLWL 120

Query: 121 YSSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCKED 180
           Y+SIL F P  V +TSELPLGSGLGSSAA CVA SAALLA S SVNVD +Q GW++  E 
Sbjct: 121 YTSILGFKPATVVVTSELPLGSGLGSSAALCVAFSAALLACSDSVNVDMKQQGWLIVGES 180

Query: 181 ELVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTKVG 240
           EL LLNKWAFE                           G+L  IKS+MPLKML+TNTKVG
Sbjct: 181 ELELLNKWAFEGEKLIHGKPSGIDNTVSTYGNMIKFRSGNLTRIKSSMPLKMLITNTKVG 240

Query: 241 RNTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAELM 300
           RNTKALVAGVSER +RHPDAM+SVFNAVDSISKEL+ ++Q+ A DD+SLT KEE+L ELM
Sbjct: 241 RNTKALVAGVSERTLRHPDAMNSVFNAVDSISKELANVIQTPAPDDLSLTSKEEKLEELM 300

Query: 301 EMNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEVIA 336
           EMNQGLLQCMGVSH SIET+LRTT KY+L SKLTGAGGGGCVLTLLP LLSGTIVD+VIA
Sbjct: 301 EMNQGLLQCMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTIVDKVIA 360

[Close]

BLAST of Carg12895 vs. TrEMBL
Match: tr|A0A2P4MBP9|A0A2P4MBP9_QUESU (Mevalonate kinase OS=Quercus suber OX=58331 GN=CFP56_58350 PE=3 SV=1)

HSP 1 Score: 454.9 bits (1169), Expect = 1.6e-124
Identity = 258/385 (67.01%), Postives = 287/385 (74.55%), Query Frame = 0


Query: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASVNLYTTASVRLPCSS---------------- 60
           MEVKARAPGKIILAGEHAVVHGSTAVAAS++LYT  S+R P  S                
Sbjct: 1   MEVKARAPGKIILAGEHAVVHGSTAVAASLDLYTYVSLRFPTPSDNDEFLRLQLKDLALE 60

Query: 61  ----VSRIKEAL---GGFVGPISTPTSCPAECLKAIASLVEYQNIPEAKIKLASGVSAFL 120
               V+RIK+AL   G  +   S PTSC  E +K+IA+ VE QNIPEAKI LASGVSAFL
Sbjct: 61  FSWPVARIKDALPEAGSLLS--SKPTSCSIETMKSIAAQVEEQNIPEAKIGLASGVSAFL 120

Query: 121 WLYSSILRFVPVDVAITSELPLGSGLGSSAAFCVAISAALLALSGSVNVDQEQCGWMVCK 180
           WLYS I  F P  V ITSELPLG+GLGSSAAFCVA+SAALL+ S SV++D  Q GW    
Sbjct: 121 WLYSCIHGFKPATVVITSELPLGAGLGSSAAFCVALSAALLSFSDSVSLDISQQGWTAFG 180

Query: 181 EDELVLLNKWAFE---------------------------GSLDLIKSNMPLKMLVTNTK 240
           E EL LLNKWAFE                           G+L LIKSNMPLKML+TNTK
Sbjct: 181 ESELELLNKWAFEGEKIIHGKPSGLDNTVSTYGNMIKFRSGNLTLIKSNMPLKMLITNTK 240

Query: 241 VGRNTKALVAGVSERAIRHPDAMSSVFNAVDSISKELSILLQSLAHDDMSLTEKEEQLAE 300
           VGRNTKALVAGVSER IRHPDAMS VFNAVDSIS ELS ++QS A D++S+TEKEE++AE
Sbjct: 241 VGRNTKALVAGVSERTIRHPDAMSLVFNAVDSISNELSTIIQSPAPDELSITEKEEKIAE 300

Query: 301 LMEMNQGLLQCMGVSHGSIETILRTTSKYELVSKLTGAGGGGCVLTLLPNLLSGTIVDEV 336
           LMEMNQGLLQCMGVSH SIET+LRTT KY+L SKLTGAGGGGCVLTLLP LLSGT+VD+V
Sbjct: 301 LMEMNQGLLQCMGVSHASIETVLRTTLKYKLASKLTGAGGGGCVLTLLPTLLSGTVVDKV 360

The following BLAST results are available for this feature:

BLAST of Carg12895 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_023545825.1	1.8e-172	87.31	mevalonate kinase-like isoform X2 [Cucurbita pepo subsp. pepo]	[more]
XP_022946758.1	1.3e-170	85.71	mevalonate kinase-like [Cucurbita moschata]	[more]
XP_022999117.1	8.6e-167	85.23	mevalonate kinase-like [Cucurbita maxima]	[more]
XP_023545824.1	3.6e-149	85.39	mevalonate kinase-like isoform X1 [Cucurbita pepo subsp. pepo]	[more]
XP_004139185.1	9.0e-148	76.17	PREDICTED: mevalonate kinase [Cucumis sativus] >KGN60892.1 hypothetical protein ...	[more]

BLAST of Carg12895 vs. TAIR10


Match Name	E-value	Identity	Description
AT5G27450.1	7.4e-104	56.36	mevalonate kinase	[more]

BLAST of Carg12895 vs. Swiss-Prot


Match Name	E-value	Identity	Description
sp\|P46086\|KIME_ARATH	1.3e-102	56.36	Mevalonate kinase OS=Arabidopsis thaliana OX=3702 GN=At5g27450 PE=2 SV=1	[more]
sp\|Q03426\|KIME_HUMAN	1.5e-45	37.30	Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1	[more]
sp\|P17256\|KIME_RAT	4.1e-43	35.53	Mevalonate kinase OS=Rattus norvegicus OX=10116 GN=Mvk PE=1 SV=1	[more]
sp\|Q9R008\|KIME_MOUSE	1.2e-42	35.58	Mevalonate kinase OS=Mus musculus OX=10090 GN=Mvk PE=1 SV=1	[more]
sp\|Q5E9T8\|KIME_BOVIN	1.2e-39	34.74	Mevalonate kinase OS=Bos taurus OX=9913 GN=MVK PE=2 SV=1	[more]

BLAST of Carg12895 vs. TrEMBL


Match Name	E-value	Identity	Description
tr\|A0A0A0LJK4\|A0A0A0LJK4_CUCSA	5.9e-148	76.17	Mevalonate kinase OS=Cucumis sativus OX=3659 GN=Csa_2G021630 PE=3 SV=1	[more]
tr\|A0A1S3C084\|A0A1S3C084_CUCME	1.3e-147	75.91	Mevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103495132 PE=3 SV=1	[more]
tr\|A0A1S3C0R0\|A0A1S3C0R0_CUCME	1.2e-137	72.28	Mevalonate kinase OS=Cucumis melo OX=3656 GN=LOC103495150 PE=3 SV=1	[more]
tr\|A0A2K2AB31\|A0A2K2AB31_POPTR	1.4e-125	66.84	Mevalonate kinase OS=Populus trichocarpa OX=3694 GN=POPTR_005G035300v3 PE=3 SV=1	[more]
tr\|A0A2P4MBP9\|A0A2P4MBP9_QUESU	1.6e-124	67.01	Mevalonate kinase OS=Quercus suber OX=58331 GN=CFP56_58350 PE=3 SV=1	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **Molecular Function**
Term	Definition
GO:0005524	ATP binding

Vocabulary: **INTERPRO**
Term	Definition
IPR020568	Ribosomal_S5_D2-typ_fold
IPR006203	GHMP_knse_ATP-bd_CS
IPR013750	GHMP_kinase_C_dom
IPR006204	GHMP_kinase_N_dom
IPR036554	GHMP_kinase_C_sf
IPR014721	Ribosomal_S5_D2-typ_fold_subgr

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0008150	biological_process
biological_process	GO:0008299	isoprenoid biosynthetic process
biological_process	GO:0016310	phosphorylation
biological_process	GO:0006694	steroid biosynthetic process
cellular_component	GO:0005575	cellular_component
cellular_component	GO:0005737	cytoplasm
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004496	mevalonate kinase activity

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Carg12895-RA	Carg12895-RA	mRNA

InterPro

Analysis Name: InterPro Annotations of silver-seed gourd
Date Performed: 2019-03-07


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00959	MEVGALKINASE	coord: 115..137 score: 49.87 coord: 7..31 score: 37.65 coord: 282..299 score: 52.29
None	No IPR available	PANTHER	PTHR43290	FAMILY NOT NAMED	coord: 2..171
None	No IPR available	PANTHER	PTHR43290:SF2	MEVALONATE KINASE	coord: 176..334 coord: 2..171
None	No IPR available	PANTHER	PTHR43290	FAMILY NOT NAMED	coord: 176..334
IPR014721	Ribosomal protein S5 domain 2-type fold, subgroup	GENE3D	G3DSA:3.30.230.10		coord: 1..173 e-value: 2.6E-34 score: 121.0
IPR036554	GHMP kinase, C-terminal domain superfamily	GENE3D	G3DSA:3.30.70.890		coord: 180..328 e-value: 9.2E-46 score: 157.1
IPR036554	GHMP kinase, C-terminal domain superfamily	SUPERFAMILY	SSF55060	GHMP Kinase, C-terminal domain	coord: 180..334
IPR006204	GHMP kinase N-terminal domain	PFAM	PF00288	GHMP_kinases_N	coord: 110..172 e-value: 1.6E-11 score: 44.1
IPR013750	GHMP kinase, C-terminal domain	PFAM	PF08544	GHMP_kinases_C	coord: 246..298 e-value: 4.2E-6 score: 26.9
IPR006203	GHMP kinase, ATP-binding, conserved site	PROSITE	PS00627	GHMP_KINASES_ATP	coord: 117..128
IPR020568	Ribosomal protein S5 domain 2-type fold	SUPERFAMILY	SSF54211	Ribosomal protein S5 domain 2-like	coord: 2..172

Synteny

The following gene(s) are orthologous to this gene:


Gene	Orthologue	Organism	Block
Carg12895	Cla019880	Watermelon (97103) v1	carwmB0907
Carg12895	Csa2G021630	Cucumber (Chinese Long) v2	carcuB0917
Carg12895	MELO3C004278	Melon (DHL92) v3.5.1	carmeB0893
Carg12895	ClCG02G015900	Watermelon (Charleston Gray)	carwcgB0883
Carg12895	CSPI02G03820	Wild cucumber (PI 183967)	carcpiB0938
Carg12895	Cucsa.091600	Cucumber (Gy14) v1	carcgyB1020
Carg12895	CmaCh05G011470	Cucurbita maxima (Rimu)	carcmaB1246
Carg12895	CmaCh12G010790	Cucurbita maxima (Rimu)	carcmaB1241
Carg12895	CmoCh12G010960	Cucurbita moschata (Rifu)	carcmoB1212
Carg12895	CmoCh05G011580	Cucurbita moschata (Rifu)	carcmoB1216
Carg12895	Lsi11G005310	Bottle gourd (USVL1VR-Ls)	carlsiB822
Carg12895	Cp4.1LG07g09120	Cucurbita pepo (Zucchini)	carcpeB1256
Carg12895	CsGy2G003910	Cucumber (Gy14) v2	carcgybB0890
Carg12895	MELO3C004278.2	Melon (DHL92) v3.6.1	carmedB0900
Carg12895	CsaV3_2G005140	Cucumber (Chinese Long) v3	carcucB0940
Carg12895	Cla97C02G041670	Watermelon (97103) v2	carwmbB0946
Carg12895	Bhi05G001652	Wax gourd	carwgoB1046

The following gene(s) are paralogous to this gene:


Gene	Paralogue	Organism	Block
Carg12895	Carg17554	Silver-seed gourd	carcarB587

The following block(s) are covering this gene:


Gene	Organism	Block
Carg12895	Cucurbita pepo (Zucchini)	carcpeB1252
Carg12895	Watermelon (97103) v2	carwmbB0949