MELO3C031371.2 (gene) Melon (DHL92) v3.6.1

Overview
NameMELO3C031371.2
Typegene
OrganismCucumis melo (Melon (DHL92) v3.6.1)
DescriptionProtein BREAST CANCER SUSCEPTIBILITY 1-like protein
Locationchr05 : 12122220 .. 12124288 (-)
Genome Viewer
Sequences
The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDS
Hold the cursor over a type above to highlight its positions in the sequence below.
ATGTCCAAATTATGGAAGCCAGATGTGACTCATGTTATTGCGTCCGCAGATGAGAATGGTGCATGCAGTCAGACATATGAAGTCCTTATGGGGATATTGAATGGAATATGGATTGTAAGTACAATTCTAATGATGTTTTTTTTTCTTTTTGAAATTATGCTTTCATTTAGATGAAAGTTGAAGTAATCATCATCAATATTAGATGTGATCTGAATTTTATATGATTCTTTTTAGTTTTTTTATTTTTGTGCTTTGCACCAGTTGGCTCACTCCCGCTTTGGGCCATTTATAGTTCCTTTTTAGAGGAAGGACGTATGTTATGCCATTTTTCTTATTCTTTCTTCTTCTATATATATATATATATATATATTTAAGAGCATATACAACTCTACCTATTTCATAAGATACAAATATCATAATTTGTACTGTAGATAGATATACATACATTATGTCTGAAGTATTAGGCTATGAGCCAGATATTACAAAAATGGAGTCTGGACAGAAACAATTCGAGAATGGATATTTTCTGCTATTCACTACTATAGAAAAAAAAATCATATATTTTTGTTTTGTTAATTTTTTTATGCACTTGGTTGTTCGTATTCGTTTTATAAATTTTTTGTGCACTTGGTTGATCGGCATGTCTTGTTCCTTTAATCTGCACAACTGACTTAATTTTCAACATTTAAAGCTTTGTAAGAATTAATGTATTTTGACTAGTTATAGTTAAATTGTTGTTTCAGGGATTTCATGGCTTTTTATGCATCCTCCAAAACTTGCCTGGCTTTAAAGTCTCATTTGAGCATATAATGCTTAAACTAAAGGCATTGATCTTCTTAATAAACATTGGATAACTATTTTCAGGATATGGCATGACTCATTAGCAAAATTAATCGCTCATCCATTGGTCCCTTGCCATCTTGCTATTCTCCATCCCTGTAAGTCTAAAATTATAGTTTAATTAAGTTTATTGCATTTCGATATGATGTTGTGAAAAGTCAAATTTCCCTAGAATTTATTTATTTTGTTAAGCAAACCAAGCTTTCATTGAAAAGGATGATATTATTTACAAAGGTATACAAGTAGCCGAACTCACAAAAAGAGTTCTCATTGAAATTAAAGATTTGATTGCCAAGCTTTCTTTCTTTCTTTCTTTTTCCAGTTTGTTTTTTTATGCTTGCGTTCCTTAGTTTTTGAGGGACCTATTTCATTAATCAATCCCACTTTAGTTTCCTTATTTTCCAAATTGTGAACAACTTTTATTAACAAGTCGATAGAGTTTGCTGTTTTAGATTTCCAAAAGGTTCATTTATTATTTTGCATTTATGACCACAGCTGCACATTATAGCCAACATACATATTTTCTTAACGAAGAGATAATATGTTTGAAGAATTAACTTCGTGAATTGAGACGACTCAATTCATGATTTCATGTGGGGTCTAAAGTTGAAATCCTTATTCTTTTCTACACGTAGGAAAACACTTATTAAGAGCATGTTGTGAAAGAATCCAGAGCATATAGGCCAAATGTTACCTTTTCCTCGTATTTACAGTTTACGGACTTTAAGATTTTCATATTAGACATATATAGAGTTAGGCTGACAATTTTTCCATATGGTAAAAGTTTGGGCTATTGTAATAAGTATGTAATGTTAATTATATGTATGGTTCAATGATATATGCAATTTATTGAAATATTAGTTCATTGATGGAAAGTTTTGGTTGATTCAATTGTTCAATTAATATGACTAGTTTAGCAACTTTGTGAAATCTCAAAGGCTCTACGAAGGACTTCAAAACAGGTGCAATAAAATTATATGGATATTTCAAATTGTACAATTTTTCATTTGAAAAAATAAAAAAGTCAAGTATAATTTTACTTGACGATTAAAAACTAAGAAAAACCCTCTTGTTCTTGACACTACATTACTTGACGCATTGAAAAGCATTAAGTAAACCAATACTTGATAGGTAAAAATGTCAAGTAAATCTTTTGCTGTAGTAGATACGTCGGGAATGGGTTTGCTATGCCTGATGTAGACATTTACGGTGTTGGGAGAAAGGAATAA

mRNA sequence

ATGTCCAAATTATGGAAGCCAGATGTGACTCATGTTATTGCGTCCGCAGATGAGAATGGTGCATGCAGTCAGACATATGAAGTCCTTATGGGGATATTGAATGGAATATGGATTTTTAGCAACTTTGTGAAATCTCAAAGGCTCTACGAAGGACTTCAAAACAGATACGTCGGGAATGGGTTTGCTATGCCTGATGTAGACATTTACGGTGTTGGGAGAAAGGAATAA

Coding sequence (CDS)

ATGTCCAAATTATGGAAGCCAGATGTGACTCATGTTATTGCGTCCGCAGATGAGAATGGTGCATGCAGTCAGACATATGAAGTCCTTATGGGGATATTGAATGGAATATGGATTTTTAGCAACTTTGTGAAATCTCAAAGGCTCTACGAAGGACTTCAAAACAGATACGTCGGGAATGGGTTTGCTATGCCTGATGTAGACATTTACGGTGTTGGGAGAAAGGAATAA

Protein sequence

MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFSNFVKSQRLYEGLQNRYVGNGFAMPDVDIYGVGRKE
Homology
[Close]
BLAST of MELO3C031371.2 vs. NCBI nr
Match: XP_008447388.1 (PREDICTED: BRCA1-associated RING domain protein 1 isoform X1 [Cucumis melo])

HSP 1 Score: 77.8 bits (190), Expect = 1.7e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 484 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 523

[Close]
BLAST of MELO3C031371.2 vs. NCBI nr
Match: XP_008447389.1 (PREDICTED: BRCA1-associated RING domain protein 1 isoform X2 [Cucumis melo])

HSP 1 Score: 77.8 bits (190), Expect = 1.7e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 483 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 522

[Close]
BLAST of MELO3C031371.2 vs. NCBI nr
Match: XP_011651611.1 (PREDICTED: protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X1 [Cucumis sativus] >KGN58286.1 hypothetical protein Csa_3G608160 [Cucumis sativus])

HSP 1 Score: 77.8 bits (190), Expect = 1.7e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 484 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 523

[Close]
BLAST of MELO3C031371.2 vs. NCBI nr
Match: XP_011651612.1 (PREDICTED: protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X2 [Cucumis sativus])

HSP 1 Score: 77.8 bits (190), Expect = 1.7e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 483 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 522

[Close]
BLAST of MELO3C031371.2 vs. NCBI nr
Match: XP_022156623.1 (BRCA1-associated RING domain protein 1 [Momordica charantia])

HSP 1 Score: 74.7 bits (182), Expect = 1.5e-10
Identity = 31/38 (81.58%), Postives = 36/38 (94.74%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWI 39
           +SK WKPDVTHVIAS D+NGAC++TY+VLMGILNGIWI
Sbjct: 483 VSKFWKPDVTHVIASTDDNGACTRTYKVLMGILNGIWI 520

[Close]
BLAST of MELO3C031371.2 vs. TAIR10
Match: AT1G04020.1 (breast cancer associated RING 1)

HSP 1 Score: 62.4 bits (150), Expect = 1.4e-10
Identity = 26/40 (65.00%), Postives = 32/40 (80.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +S+ W P VTHVIAS DE GAC++T +VLMGILNG WI +
Sbjct: 517 ISRYWNPSVTHVIASTDEKGACTRTLKVLMGILNGKWIIN 556

[Close]
BLAST of MELO3C031371.2 vs. TAIR10
Match: AT4G21070.1 (breast cancer susceptibility1)

HSP 1 Score: 51.2 bits (121), Expect = 3.2e-07
Identity = 22/40 (55.00%), Postives = 28/40 (70.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SK W   VTHVIAS +ENGAC +T + +M IL G WI +
Sbjct: 759 ISKNWDSTVTHVIASINENGACKRTLKFMMAILEGKWILT 798

[Close]
BLAST of MELO3C031371.2 vs. Swiss-Prot
Match: sp|F4I443|BARD1_ARATH (BRCA1-associated RING domain protein 1 OS=Arabidopsis thaliana OX=3702 GN=BARD1 PE=1 SV=1)

HSP 1 Score: 62.4 bits (150), Expect = 2.5e-09
Identity = 26/40 (65.00%), Postives = 32/40 (80.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +S+ W P VTHVIAS DE GAC++T +VLMGILNG WI +
Sbjct: 517 ISRYWNPSVTHVIASTDEKGACTRTLKVLMGILNGKWIIN 556

[Close]
BLAST of MELO3C031371.2 vs. Swiss-Prot
Match: sp|Q8RXD4|BRCA1_ARATH (Protein BREAST CANCER SUSCEPTIBILITY 1 homolog OS=Arabidopsis thaliana OX=3702 GN=BRCA1 PE=1 SV=1)

HSP 1 Score: 51.2 bits (121), Expect = 5.7e-06
Identity = 22/40 (55.00%), Postives = 28/40 (70.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SK W   VTHVIAS +ENGAC +T + +M IL G WI +
Sbjct: 759 ISKNWDSTVTHVIASINENGACKRTLKFMMAILEGKWILT 798

[Close]
BLAST of MELO3C031371.2 vs. TrEMBL
Match: tr|A0A1S3BI76|A0A1S3BI76_CUCME (BRCA1-associated RING domain protein 1 isoform X1 OS=Cucumis melo OX=3656 GN=LOC103489848 PE=4 SV=1)

HSP 1 Score: 77.8 bits (190), Expect = 1.2e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 484 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 523

[Close]
BLAST of MELO3C031371.2 vs. TrEMBL
Match: tr|A0A1S3BGS2|A0A1S3BGS2_CUCME (BRCA1-associated RING domain protein 1 isoform X2 OS=Cucumis melo OX=3656 GN=LOC103489848 PE=4 SV=1)

HSP 1 Score: 77.8 bits (190), Expect = 1.2e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 483 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 522

[Close]
BLAST of MELO3C031371.2 vs. TrEMBL
Match: tr|A0A0A0LDW6|A0A0A0LDW6_CUCSA (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G608160 PE=4 SV=1)

HSP 1 Score: 77.8 bits (190), Expect = 1.2e-11
Identity = 33/40 (82.50%), Postives = 38/40 (95.00%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           +SKLWKPDVTHVIAS DENGAC++TY+VLMGILNGIWI +
Sbjct: 484 VSKLWKPDVTHVIASTDENGACTRTYKVLMGILNGIWILN 523

[Close]
BLAST of MELO3C031371.2 vs. TrEMBL
Match: tr|A0A2J6JTQ2|A0A2J6JTQ2_LACSA (Uncharacterized protein OS=Lactuca sativa OX=4236 GN=LSAT_2X90841 PE=4 SV=1)

HSP 1 Score: 65.9 bits (159), Expect = 4.6e-08
Identity = 26/38 (68.42%), Postives = 33/38 (86.84%), Query Frame = 0 

Query: 3   KLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           + WKP+VTHVIA+ D NGAC++TY+VLM ILNG+WI S
Sbjct: 319 RYWKPNVTHVIAATDSNGACTRTYKVLMAILNGVWIVS 356

[Close]
BLAST of MELO3C031371.2 vs. TrEMBL
Match: tr|A0A0K9RVI4|A0A0K9RVI4_SPIOL (Uncharacterized protein OS=Spinacia oleracea OX=3562 GN=SOVF_023940 PE=4 SV=1)

HSP 1 Score: 65.9 bits (159), Expect = 4.6e-08
Identity = 28/40 (70.00%), Postives = 33/40 (82.50%), Query Frame = 0 

Query: 1   MSKLWKPDVTHVIASADENGACSQTYEVLMGILNGIWIFS 41
           ++K W PDVTHVIA+ D NGACS+T +VLMGILNG WI S
Sbjct: 454 VTKAWNPDVTHVIAATDANGACSRTLKVLMGILNGRWILS 493

The following BLAST results are available for this feature:
BLAST of MELO3C031371.2 vs. NCBI nr
Match NameE-valueIdentityDescription
XP_008447388.11.7e-1182.50PREDICTED: BRCA1-associated RING domain protein 1 isoform X1 [Cucumis melo][more]
XP_008447389.11.7e-1182.50PREDICTED: BRCA1-associated RING domain protein 1 isoform X2 [Cucumis melo][more]
XP_011651611.11.7e-1182.50PREDICTED: protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X1 [Cucumis sa... [more]
XP_011651612.11.7e-1182.50PREDICTED: protein BREAST CANCER SUSCEPTIBILITY 1 homolog isoform X2 [Cucumis sa... [more]
XP_022156623.11.5e-1081.58BRCA1-associated RING domain protein 1 [Momordica charantia][more]
BLAST of MELO3C031371.2 vs. TAIR10
Match NameE-valueIdentityDescription
AT1G04020.11.4e-1065.00breast cancer associated RING 1[more]
AT4G21070.13.2e-0755.00breast cancer susceptibility1[more]
BLAST of MELO3C031371.2 vs. Swiss-Prot
Match NameE-valueIdentityDescription
sp|F4I443|BARD1_ARATH2.5e-0965.00BRCA1-associated RING domain protein 1 OS=Arabidopsis thaliana OX=3702 GN=BARD1 ... [more]
sp|Q8RXD4|BRCA1_ARATH5.7e-0655.00Protein BREAST CANCER SUSCEPTIBILITY 1 homolog OS=Arabidopsis thaliana OX=3702 G... [more]
BLAST of MELO3C031371.2 vs. TrEMBL
Match NameE-valueIdentityDescription
tr|A0A1S3BI76|A0A1S3BI76_CUCME1.2e-1182.50BRCA1-associated RING domain protein 1 isoform X1 OS=Cucumis melo OX=3656 GN=LOC... [more]
tr|A0A1S3BGS2|A0A1S3BGS2_CUCME1.2e-1182.50BRCA1-associated RING domain protein 1 isoform X2 OS=Cucumis melo OX=3656 GN=LOC... [more]
tr|A0A0A0LDW6|A0A0A0LDW6_CUCSA1.2e-1182.50Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G608160 PE=4 SV=1[more]
tr|A0A2J6JTQ2|A0A2J6JTQ2_LACSA4.6e-0868.42Uncharacterized protein OS=Lactuca sativa OX=4236 GN=LSAT_2X90841 PE=4 SV=1[more]
tr|A0A0K9RVI4|A0A0K9RVI4_SPIOL4.6e-0870.00Uncharacterized protein OS=Spinacia oleracea OX=3562 GN=SOVF_023940 PE=4 SV=1[more]
Annotated Terms
The following terms have been associated with this gene:
Vocabulary: Biological Process
TermDefinition
GO:0006281DNA repair
GO:0006974cellular response to DNA damage stimulus
Vocabulary: INTERPRO
TermDefinition
IPR031099BRCA1-associated
IPR036420BRCT_dom_sf
GO Annotation
GO Assignments
This gene is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006974 cellular response to DNA damage stimulus
biological_process GO:0006281 DNA repair
cellular_component GO:0005575 cellular_component
molecular_function GO:0046872 metal ion binding
molecular_function GO:0008270 zinc ion binding
Relationships

The following mRNA feature(s) are a part of this gene:

Feature NameUnique NameType
MELO3C031371.2.1MELO3C031371.2.1mRNA


InterPro
Analysis Name: InterPro Annotations of melon v3.6.1
Date Performed: 2018-09-25
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036420BRCT domain superfamilyGENE3DG3DSA:3.40.50.10190coord: 1..44
e-value: 1.1E-8
score: 37.2
IPR036420BRCT domain superfamilySUPERFAMILYSSF52113BRCT domaincoord: 3..39
NoneNo IPR availablePANTHERPTHR13763:SF1PROTEIN BREAST CANCER SUSCEPTIBILITY 1 HOMOLOGcoord: 2..40
IPR031099BRCA1-associatedPANTHERPTHR13763BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1coord: 2..40

Synteny
The following gene(s) are orthologous to this gene:

None

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:
GeneOrganismBlock
MELO3C031371.2Cucumber (Gy14) v2cgybmedB122
MELO3C031371.2Cucumber (Gy14) v1cgymedB443
MELO3C031371.2Cucurbita maxima (Rimu)cmamedB494
MELO3C031371.2Cucurbita maxima (Rimu)cmamedB830
MELO3C031371.2Cucurbita moschata (Rifu)cmomedB481
MELO3C031371.2Cucurbita moschata (Rifu)cmomedB823
MELO3C031371.2Cucurbita pepo (Zucchini)cpemedB125
MELO3C031371.2Cucurbita pepo (Zucchini)cpemedB627
MELO3C031371.2Wild cucumber (PI 183967)cpimedB135
MELO3C031371.2Cucumber (Chinese Long) v2cumedB135
MELO3C031371.2Bottle gourd (USVL1VR-Ls)lsimedB125
MELO3C031371.2Watermelon (97103) v1medwmB417
MELO3C031371.2Silver-seed gourdcarmedB0711
MELO3C031371.2Cucumber (Chinese Long) v3cucmedB137
MELO3C031371.2Wax gourdmedwgoB458