MELO3C025289.2 (gene) Melon (DHL92) v3.6.1 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	MELO3C025289.2
Type	gene
Organism	Cucumis melo (Melon (DHL92) v3.6.1)
Description	Werner Syndrome-like exonuclease
Location	chr02 : 18719961 .. 18720452 (+)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonfive_prime_UTRCDSthree_prime_UTR

Hold the cursor over a type above to highlight its positions in the sequence below.

AATCTTTTACCTTCGACGATGAAATCCTCACCCTCCTCACTACTTGCCCTTCCATGGTTGACATGTGGATCTCCGAAATCCTCTATATTTACCGTCTTAGACTCCACCATCTCGTCGTTGGTCTTAACATTGAGTGGCGTCCTAGCTCCGATCGTCATTTTCGTAACCTCGTCACCACTTTACAACTCTGTGTCGGTCGCTACTGCCTCATTTTCCAACATCTGCAGATCTGAAATTCCTCAGTCTTTGATCAATTTCTTAGAGGACGATACCTTCACTTTCGTTGGTGTTGGAATCGACAATGGCGTTCTGAAGCACTATAGTGATTACGACCTAAATGTTGATAACACCGTTGATCTTAGGGAGTTGGCTGCGGATGAGATATGTGGATGAGATGCAGAGTGATGAGTTGAGGACTGTCGGACTGAAGACTTTGGAGAGAGAGGTTCTTGGGAGGGAGAATGGTAAAATCTTTCTAGGGATTTTGATTTT

mRNA sequence

AATCTTTTACCTTCGACGATGAAATCCTCACCCTCCTCACTACTTGCCCTTCCATGGTTGACATGTGGATCTCCGAAATCCTCTATATTTACCGTCTTAGACTCCACCATCTCGTCGTTGGTCTTAACATTGAGTGGCGTCCTAGCTCCGATCGTCATTTTCGTAACCTCGTCACCACTTTACAACTCTGTGTCGGTCGCTACTGCCTCATTTTCCAACATCTGCAGATCTGAAATTCCTCAGTCTTTGATCAATTTCTTAGAGGACGATACCTTCACTTTCGTTGGTGTTGGAATCGACAATGGCGTTCTGAAGCACTATAGTGATTACGACCTAAATGTTGATAACACCGTTGATCTTAGGGAGTTGGCTGCGGATGAGATATGTGGATGAGATGCAGAGTGATGAGTTGAGGACTGTCGGACTGAAGACTTTGGAGAGAGAGGTTCTTGGGAGGGAGAATGGTAAAATCTTTCTAGGGATTTTGATTTT

Coding sequence (CDS)

ATGAAATCCTCACCCTCCTCACTACTTGCCCTTCCATGGTTGACATGTGGATCTCCGAAATCCTCTATATTTACCGTCTTAGACTCCACCATCTCGTCGTTGGTCTTAACATTGAGTGGCGTCCTAGCTCCGATCGTCATTTTCGTAACCTCGTCACCACTTTACAACTCTGTGTCGGTCGCTACTGCCTCATTTTCCAACATCTGCAGATCTGAAATTCCTCAGTCTTTGATCAATTTCTTAGAGGACGATACCTTCACTTTCGTTGGTGTTGGAATCGACAATGGCGTTCTGAAGCACTATAGTGATTACGACCTAAATGTTGATAACACCGTTGATCTTAGGGAGTTGGCTGCGGATGAGATATGTGGATGA

Protein sequence

MKSSPSSLLALPWLTCGSPKSSIFTVLDSTISSLVLTLSGVLAPIVIFVTSSPLYNSVSVATASFSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEICG

Homology

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BLAST of MELO3C025289.2 vs. NCBI nr
Match: XP_004136771.1 (PREDICTED: Werner Syndrome-like exonuclease [Cucumis sativus] >KGN59426.1 hypothetical protein Csa_3G819830 [Cucumis sativus])

HSP 1 Score: 88.2 bits (217), Expect = 2.1e-14
Identity = 45/55 (81.82%), Postives = 47/55 (85.45%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAA 120
           F  I  SE PQSLI+FLEDDTFTFVGVGIDN VLK Y+DYDLNV NTVDLRELAA
Sbjct: 91  FQLIHASETPQSLIDFLEDDTFTFVGVGIDNDVLKLYNDYDLNVANTVDLRELAA 145

[Close]

BLAST of MELO3C025289.2 vs. NCBI nr
Match: XP_010673173.1 (PREDICTED: Werner Syndrome-like exonuclease [Beta vulgaris subsp. vulgaris])

HSP 1 Score: 68.2 bits (165), Expect = 2.3e-08
Identity = 40/79 (50.63%), Postives = 45/79 (56.96%), Query Frame = 0


Query: 48  FVTSSPLYNSVSVATASFSNIC-------RSEIPQSLINFLEDDTFTFVGVGIDNGVLKH 107
           F    P  N +SV      + C          IPQSL NFL DD +TFVGVGID+ V K 
Sbjct: 53  FYNRHPSRNPISVLQLCVGHHCLVFQLQHACYIPQSLHNFLSDDDYTFVGVGIDDDVQKL 112

Query: 108 YSDYDLNVDNTVDLRELAA 120
           Y DYDL V NTVDLR LA+
Sbjct: 113 YYDYDLEVSNTVDLRTLAS 131

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BLAST of MELO3C025289.2 vs. NCBI nr
Match: XP_022147765.1 (Werner Syndrome-like exonuclease, partial [Momordica charantia])

HSP 1 Score: 67.8 bits (164), Expect = 3.0e-08
Identity = 33/56 (58.93%), Postives = 39/56 (69.64%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAAD 121
           F  I   EIP SL++FL D+TFTFVGVGID    K + DYDL V+N VDLR +A D
Sbjct: 82  FQLIHAPEIPHSLLHFLGDETFTFVGVGIDQDARKLFDDYDLTVNNAVDLRSMAVD 137

[Close]

BLAST of MELO3C025289.2 vs. NCBI nr
Match: XP_022147750.1 (Werner Syndrome-like exonuclease [Momordica charantia])

HSP 1 Score: 63.9 bits (154), Expect = 4.3e-07
Identity = 34/54 (62.96%), Postives = 38/54 (70.37%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELA 119
           F  I  SEIP+SL +FL D++FTFVGVGI   V K   DY LNV NTVDLR LA
Sbjct: 87  FQLIHASEIPRSLTDFLTDESFTFVGVGIGEDVEKLLCDYGLNVSNTVDLRNLA 140

[Close]

BLAST of MELO3C025289.2 vs. NCBI nr
Match: XP_011041345.1 (PREDICTED: Werner Syndrome-like exonuclease [Populus euphratica])

HSP 1 Score: 63.2 bits (152), Expect = 7.4e-07
Identity = 31/54 (57.41%), Postives = 41/54 (75.93%), Query Frame = 0


Query: 69  CRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEI 123
           C + IPQSL +FL D T+TFVGVGI++ V K   DY+L+V N VDLR LAA+++
Sbjct: 136 CLTGIPQSLHDFLSDMTYTFVGVGIESDVKKLTEDYELSVGNAVDLRGLAAEKL 189

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BLAST of MELO3C025289.2 vs. TrEMBL
Match: tr|A0A0A0LHC5|A0A0A0LHC5_CUCSA (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G819830 PE=4 SV=1)

HSP 1 Score: 88.2 bits (217), Expect = 1.4e-14
Identity = 45/55 (81.82%), Postives = 47/55 (85.45%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAA 120
           F  I  SE PQSLI+FLEDDTFTFVGVGIDN VLK Y+DYDLNV NTVDLRELAA
Sbjct: 91  FQLIHASETPQSLIDFLEDDTFTFVGVGIDNDVLKLYNDYDLNVANTVDLRELAA 145

[Close]

BLAST of MELO3C025289.2 vs. TrEMBL
Match: tr|B9IHJ6|B9IHJ6_POPTR (Uncharacterized protein OS=Populus trichocarpa OX=3694 GN=POPTR_016G028700v3 PE=4 SV=1)

HSP 1 Score: 62.8 bits (151), Expect = 6.4e-07
Identity = 31/54 (57.41%), Postives = 40/54 (74.07%), Query Frame = 0


Query: 69  CRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEI 123
           C + IPQSL +FL D T+TFVGVGI+  V K   DY+L+V N VDLR LAA+++
Sbjct: 99  CPTGIPQSLHDFLSDMTYTFVGVGIEGDVKKLTEDYELSVGNAVDLRGLAAEKL 152

[Close]

BLAST of MELO3C025289.2 vs. TrEMBL
Match: tr|A0A2P4N0P2|A0A2P4N0P2_QUESU (Werner syndrome atp-dependent helicase like OS=Quercus suber OX=58331 GN=CFP56_20788 PE=4 SV=1)

HSP 1 Score: 62.0 bits (149), Expect = 1.1e-06
Identity = 32/58 (55.17%), Postives = 37/58 (63.79%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEI 123
           F  I  +  P SLI FL D+ FTFVGVGI++ V K   DYDL V N VDLR LA D +
Sbjct: 67  FQLIYATHFPNSLIEFLGDEDFTFVGVGIESDVEKLLDDYDLKVGNVVDLRGLAVDRL 124

[Close]

BLAST of MELO3C025289.2 vs. TrEMBL
Match: tr|A0A2P4GQ80|A0A2P4GQ80_QUESU (Werner syndrome-like exonuclease OS=Quercus suber OX=58331 GN=CFP56_68621 PE=4 SV=1)

HSP 1 Score: 62.0 bits (149), Expect = 1.1e-06
Identity = 32/58 (55.17%), Postives = 37/58 (63.79%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEI 123
           F  I  +  P SLI FL D+ FTFVGVGI++ V K   DYDL V N VDLR LA D +
Sbjct: 90  FQLIYATHFPNSLIEFLGDEDFTFVGVGIESDVEKLLDDYDLKVGNVVDLRGLAVDRL 147

[Close]

BLAST of MELO3C025289.2 vs. TrEMBL
Match: tr|V4UVL0|V4UVL0_9ROSI (Uncharacterized protein OS=Citrus clementina OX=85681 GN=CICLE_v10012747mg PE=4 SV=1)

HSP 1 Score: 61.2 bits (147), Expect = 1.9e-06
Identity = 32/58 (55.17%), Postives = 39/58 (67.24%), Query Frame = 0


Query: 65  FSNICRSEIPQSLINFLEDDTFTFVGVGIDNGVLKHYSDYDLNVDNTVDLRELAADEI 123
           F  I    IPQSL NFL D+ +TFVGVGID  V K  ++Y L V  TVDLR LAA+++
Sbjct: 89  FQIIHARRIPQSLANFLSDEDYTFVGVGIDGDVKKLENNYGLQVFRTVDLRPLAAEDL 146

The following BLAST results are available for this feature:

BLAST of MELO3C025289.2 vs. NCBI nr


Match Name	E-value	Identity	Description
XP_004136771.1	2.1e-14	81.82	PREDICTED: Werner Syndrome-like exonuclease [Cucumis sativus] >KGN59426.1 hypoth...	[more]
XP_010673173.1	2.3e-08	50.63	PREDICTED: Werner Syndrome-like exonuclease [Beta vulgaris subsp. vulgaris]	[more]
XP_022147765.1	3.0e-08	58.93	Werner Syndrome-like exonuclease, partial [Momordica charantia]	[more]
XP_022147750.1	4.3e-07	62.96	Werner Syndrome-like exonuclease [Momordica charantia]	[more]
XP_011041345.1	7.4e-07	57.41	PREDICTED: Werner Syndrome-like exonuclease [Populus euphratica]	[more]

BLAST of MELO3C025289.2 vs. TAIR10


Match Name	E-value	Identity	Description

BLAST of MELO3C025289.2 vs. Swiss-Prot


Match Name	E-value	Identity	Description

BLAST of MELO3C025289.2 vs. TrEMBL


Match Name	E-value	Identity	Description
tr\|A0A0A0LHC5\|A0A0A0LHC5_CUCSA	1.4e-14	81.82	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_3G819830 PE=4 SV=1	[more]
tr\|B9IHJ6\|B9IHJ6_POPTR	6.4e-07	57.41	Uncharacterized protein OS=Populus trichocarpa OX=3694 GN=POPTR_016G028700v3 PE=...	[more]
tr\|A0A2P4N0P2\|A0A2P4N0P2_QUESU	1.1e-06	55.17	Werner syndrome atp-dependent helicase like OS=Quercus suber OX=58331 GN=CFP56_2...	[more]
tr\|A0A2P4GQ80\|A0A2P4GQ80_QUESU	1.1e-06	55.17	Werner syndrome-like exonuclease OS=Quercus suber OX=58331 GN=CFP56_68621 PE=4 S...	[more]
tr\|V4UVL0\|V4UVL0_9ROSI	1.9e-06	55.17	Uncharacterized protein OS=Citrus clementina OX=85681 GN=CICLE_v10012747mg PE=4 ...	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **Molecular Function**
Term	Definition
GO:0003676	nucleic acid binding

Vocabulary: **INTERPRO**
Term	Definition
IPR012337	RNaseH-like_sf
IPR036397	RNaseH_sf

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0090305	nucleic acid phosphodiester bond hydrolysis
biological_process	GO:0006139	nucleobase-containing compound metabolic process
cellular_component	GO:0005575	cellular_component
molecular_function	GO:0008408	3'-5' exonuclease activity
molecular_function	GO:0004527	exonuclease activity
molecular_function	GO:0003676	nucleic acid binding

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
MELO3C025289.2.1	MELO3C025289.2.1	mRNA

InterPro

Analysis Name: InterPro Annotations of melon v3.6.1
Date Performed: 2018-09-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036397	Ribonuclease H superfamily	GENE3D	G3DSA:3.30.420.10		coord: 64..123 e-value: 3.1E-11 score: 44.9
None	No IPR available	PANTHER	PTHR13620	3-5 EXONUCLEASE	coord: 68..121
None	No IPR available	PANTHER	PTHR13620:SF34	SUBFAMILY NOT NAMED	coord: 68..121
IPR012337	Ribonuclease H-like superfamily	SUPERFAMILY	SSF53098	Ribonuclease H-like	coord: 70..120

Synteny

The following gene(s) are orthologous to this gene:

None

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
MELO3C025289.2	Cucumber (Gy14) v2	cgybmedB048
MELO3C025289.2	Cucumber (Gy14) v1	cgymedB087
MELO3C025289.2	Cucurbita maxima (Rimu)	cmamedB060
MELO3C025289.2	Cucurbita maxima (Rimu)	cmamedB115
MELO3C025289.2	Cucurbita moschata (Rifu)	cmomedB052
MELO3C025289.2	Cucurbita moschata (Rifu)	cmomedB106
MELO3C025289.2	Cucurbita pepo (Zucchini)	cpemedB392
MELO3C025289.2	Cucurbita pepo (Zucchini)	cpemedB736
MELO3C025289.2	Wild cucumber (PI 183967)	cpimedB053
MELO3C025289.2	Cucumber (Chinese Long) v2	cumedB050
MELO3C025289.2	Bottle gourd (USVL1VR-Ls)	lsimedB425
MELO3C025289.2	Watermelon (Charleston Gray)	medwcgB249
MELO3C025289.2	Watermelon (97103) v1	medwmB277
MELO3C025289.2	Watermelon (97103) v1	medwmB288
MELO3C025289.2	Silver-seed gourd	carmedB0036
MELO3C025289.2	Silver-seed gourd	carmedB0135
MELO3C025289.2	Cucumber (Chinese Long) v3	cucmedB055
MELO3C025289.2	Watermelon (97103) v2	medwmbB251
MELO3C025289.2	Wax gourd	medwgoB290