Cucsa.108540 (gene) Cucumber (Gy14) v1 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	Cucsa.108540
Type	gene
Organism	Cucumis sativus (Cucumber (Gy14) v1)
Description	Nicastrin-related family protein
Location	scaffold00931 : 677648 .. 677779 (-)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: CDS

Hold the cursor over a type above to highlight its positions in the sequence below.

CTTGTTTTTGCTGTCTTCACTGGAGAGTCCTGGGGTTACCTTGGTAGTAGGAGATTTTTGCTTGAACTTGATTTACAGTCTGATGCTGTCAGTGGCCTCGAAAATAGATTAATTGATACGGTATACTACTGA

mRNA sequence

CTTGTTTTTGCTGTCTTCACTGGAGAGTCCTGGGGTTACCTTGGTAGTAGGAGATTTTTGCTTGAACTTGATTTACAGTCTGATGCTGTCAGTGGCCTCGAAAATAGATTAATTGATACGGTATACTACTGA

Coding sequence (CDS)

CTTGTTTTTGCTGTCTTCACTGGAGAGTCCTGGGGTTACCTTGGTAGTAGGAGATTTTTGCTTGAACTTGATTTACAGTCTGATGCTGTCAGTGGCCTCGAAAATAGATTAATTGATACGGTATACTACTGA

Protein sequence

LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVYY*

Homology

[Close]

BLAST of Cucsa.108540 vs. Swiss-Prot
Match: NICA_ARATH (Nicastrin OS=Arabidopsis thaliana GN=At3g52640/At3g52650 PE=2 SV=1)

HSP 1 Score: 64.3 bits (155), Expect = 3.8e-10
Identity = 31/41 (75.61%), Postives = 34/41 (82.93%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF V TGE+WGYLGSRRFL ELDL SDAV+GL N  I+TV
Sbjct: 302 LVFLVLTGETWGYLGSRRFLHELDLHSDAVAGLSNTSIETV 342

[Close]

BLAST of Cucsa.108540 vs. TrEMBL
Match: W9SA84_9ROSA (Uncharacterized protein OS=Morus notabilis GN=L484_004947 PE=4 SV=1)

HSP 1 Score: 74.3 bits (181), Expect = 4.1e-11
Identity = 35/43 (81.40%), Postives = 38/43 (88.37%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVYY 44
           LVF V TGESWGYLGSRRFLLELDLQSDAVSGL+N L + VY+
Sbjct: 295 LVFLVLTGESWGYLGSRRFLLELDLQSDAVSGLDNSLFEMVYF 337

[Close]

BLAST of Cucsa.108540 vs. TrEMBL
Match: A0A067JSP2_JATCU (Uncharacterized protein OS=Jatropha curcas GN=JCGZ_22540 PE=4 SV=1)

HSP 1 Score: 72.8 bits (177), Expect = 1.2e-10
Identity = 33/41 (80.49%), Postives = 40/41 (97.56%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF+VFTGE+WGYLGSRRFLLELDL+SDAVSGL ++L++TV
Sbjct: 298 LVFSVFTGEAWGYLGSRRFLLELDLRSDAVSGLNDKLVETV 338

[Close]

BLAST of Cucsa.108540 vs. TrEMBL
Match: M1B118_SOLTU (Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400013310 PE=4 SV=1)

HSP 1 Score: 72.4 bits (176), Expect = 1.5e-10
Identity = 35/42 (83.33%), Postives = 38/42 (90.48%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVY 43
           LVFAVFTGE+WGYLGSRRFLLELD  SDAVSGL+  LI+TVY
Sbjct: 140 LVFAVFTGEAWGYLGSRRFLLELDQHSDAVSGLDLALIETVY 181

[Close]

BLAST of Cucsa.108540 vs. TrEMBL
Match: M1B119_SOLTU (Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400013310 PE=4 SV=1)

HSP 1 Score: 69.7 bits (169), Expect = 1.0e-09
Identity = 34/41 (82.93%), Postives = 37/41 (90.24%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVFAVFTGE+WGYLGSRRFLLELD  SDAVSGL+  LI+TV
Sbjct: 140 LVFAVFTGEAWGYLGSRRFLLELDQHSDAVSGLDLALIETV 180

[Close]

BLAST of Cucsa.108540 vs. TrEMBL
Match: B9H3E1_POPTR (Nicastrin-related family protein OS=Populus trichocarpa GN=POPTR_0004s08120g PE=4 SV=2)

HSP 1 Score: 69.3 bits (168), Expect = 1.3e-09
Identity = 32/41 (78.05%), Postives = 38/41 (92.68%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF+VFTGE+WGYLGSRRFL ELDLQS+AV+GL + LI+TV
Sbjct: 299 LVFSVFTGEAWGYLGSRRFLFELDLQSEAVNGLNSSLIETV 339

[Close]

BLAST of Cucsa.108540 vs. TAIR10
Match: AT3G52640.2 (AT3G52640.2 Zn-dependent exopeptidases superfamily protein)

HSP 1 Score: 64.3 bits (155), Expect = 2.1e-11
Identity = 31/41 (75.61%), Postives = 34/41 (82.93%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF V TGE+WGYLGSRRFL ELDL SDAV+GL N  I+TV
Sbjct: 302 LVFLVLTGETWGYLGSRRFLHELDLHSDAVAGLSNTSIETV 342

[Close]

BLAST of Cucsa.108540 vs. NCBI nr
Match: gi|449445945|ref|XP_004140732.1| (PREDICTED: nicastrin [Cucumis sativus])

HSP 1 Score: 84.7 bits (208), Expect = 4.3e-14
Identity = 41/42 (97.62%), Postives = 42/42 (100.00%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVY 43
           LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV+
Sbjct: 293 LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVF 334

[Close]

BLAST of Cucsa.108540 vs. NCBI nr
Match: gi|659114563|ref|XP_008457115.1| (PREDICTED: nicastrin isoform X1 [Cucumis melo])

HSP 1 Score: 79.0 bits (193), Expect = 2.4e-12
Identity = 38/42 (90.48%), Postives = 39/42 (92.86%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVY 43
           LVF VFTGESWGYLGSRRFLLELDLQSDAVSGL NRLID V+
Sbjct: 311 LVFVVFTGESWGYLGSRRFLLELDLQSDAVSGLSNRLIDMVF 352

[Close]

BLAST of Cucsa.108540 vs. NCBI nr
Match: gi|659114565|ref|XP_008457117.1| (PREDICTED: nicastrin isoform X2 [Cucumis melo])

HSP 1 Score: 77.8 bits (190), Expect = 5.3e-12
Identity = 38/41 (92.68%), Postives = 38/41 (92.68%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF VFTGESWGYLGSRRFLLELDLQSDAVSGL NRLID V
Sbjct: 311 LVFVVFTGESWGYLGSRRFLLELDLQSDAVSGLSNRLIDMV 351

[Close]

BLAST of Cucsa.108540 vs. NCBI nr
Match: gi|703126013|ref|XP_010103453.1| (hypothetical protein L484_004947 [Morus notabilis])

HSP 1 Score: 74.3 bits (181), Expect = 5.8e-11
Identity = 35/43 (81.40%), Postives = 38/43 (88.37%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTVYY 44
           LVF V TGESWGYLGSRRFLLELDLQSDAVSGL+N L + VY+
Sbjct: 295 LVFLVLTGESWGYLGSRRFLLELDLQSDAVSGLDNSLFEMVYF 337

[Close]

BLAST of Cucsa.108540 vs. NCBI nr
Match: gi|643712557|gb|KDP25818.1| (hypothetical protein JCGZ_22540 [Jatropha curcas])

HSP 1 Score: 72.8 bits (177), Expect = 1.7e-10
Identity = 33/41 (80.49%), Postives = 40/41 (97.56%), Query Frame = 1


Query: 1   LVFAVFTGESWGYLGSRRFLLELDLQSDAVSGLENRLIDTV 42
           LVF+VFTGE+WGYLGSRRFLLELDL+SDAVSGL ++L++TV
Sbjct: 298 LVFSVFTGEAWGYLGSRRFLLELDLRSDAVSGLNDKLVETV 338

The following BLAST results are available for this feature:

BLAST of Cucsa.108540 vs. Swiss-Prot


Match Name	E-value	Identity	Description
NICA_ARATH	3.8e-10	75.61	Nicastrin OS=Arabidopsis thaliana GN=At3g52640/At3g52650 PE=2 SV=1	[more]

BLAST of Cucsa.108540 vs. TrEMBL


Match Name	E-value	Identity	Description
W9SA84_9ROSA	4.1e-11	81.40	Uncharacterized protein OS=Morus notabilis GN=L484_004947 PE=4 SV=1	[more]
A0A067JSP2_JATCU	1.2e-10	80.49	Uncharacterized protein OS=Jatropha curcas GN=JCGZ_22540 PE=4 SV=1	[more]
M1B118_SOLTU	1.5e-10	83.33	Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400013310 PE=4 SV=1	[more]
M1B119_SOLTU	1.0e-09	82.93	Uncharacterized protein OS=Solanum tuberosum GN=PGSC0003DMG400013310 PE=4 SV=1	[more]
B9H3E1_POPTR	1.3e-09	78.05	Nicastrin-related family protein OS=Populus trichocarpa GN=POPTR_0004s08120g PE=...	[more]

BLAST of Cucsa.108540 vs. TAIR10


Match Name	E-value	Identity	Description
AT3G52640.2	2.1e-11	75.61	Zn-dependent exopeptidases superfamily protein	[more]

BLAST of Cucsa.108540 vs. NCBI nr


Match Name	E-value	Identity	Description
gi\|449445945\|ref\|XP_004140732.1\|	4.3e-14	97.62	PREDICTED: nicastrin [Cucumis sativus]	[more]
gi\|659114563\|ref\|XP_008457115.1\|	2.4e-12	90.48	PREDICTED: nicastrin isoform X1 [Cucumis melo]	[more]
gi\|659114565\|ref\|XP_008457117.1\|	5.3e-12	92.68	PREDICTED: nicastrin isoform X2 [Cucumis melo]	[more]
gi\|703126013\|ref\|XP_010103453.1\|	5.8e-11	81.40	hypothetical protein L484_004947 [Morus notabilis]	[more]
gi\|643712557\|gb\|KDP25818.1\|	1.7e-10	80.49	hypothetical protein JCGZ_22540 [Jatropha curcas]	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **INTERPRO**
Term	Definition
IPR008710	Nicastrin

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0016485	protein processing

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0016485	protein processing
cellular_component	GO:0005783	endoplasmic reticulum
cellular_component	GO:0005798	Golgi-associated vesicle
cellular_component	GO:0016021	integral component of membrane
cellular_component	GO:0005774	vacuolar membrane
molecular_function	GO:0003674	molecular_function

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
Cucsa.108540.1	Cucsa.108540.1	mRNA

InterPro

Analysis Name: InterPro Annotations of cucumber (Gy14)
Date Performed: 2017-01-17


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR008710	Nicastrin	PFAM	PF05450	Nicastrin	coord: 1..41 score: 1.6

Synteny

The following gene(s) are orthologous to this gene:

None

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
Cucsa.108540	Cucumber (Chinese Long) v3	cgycucB137
Cucsa.108540	Watermelon (97103) v2	cgywmbB148
Cucsa.108540	Wax gourd	cgywgoB171
Cucsa.108540	Cucurbita maxima (Rimu)	cgycmaB0247
Cucsa.108540	Cucurbita maxima (Rimu)	cgycmaB0250
Cucsa.108540	Cucurbita moschata (Rifu)	cgycmoB0246
Cucsa.108540	Cucurbita moschata (Rifu)	cgycmoB0249
Cucsa.108540	Wild cucumber (PI 183967)	cgycpiB133
Cucsa.108540	Cucumber (Chinese Long) v2	cgycuB132
Cucsa.108540	Melon (DHL92) v3.5.1	cgymeB144
Cucsa.108540	Watermelon (Charleston Gray)	cgywcgB153
Cucsa.108540	Watermelon (97103) v1	cgywmB153
Cucsa.108540	Cucurbita pepo (Zucchini)	cgycpeB0242
Cucsa.108540	Cucurbita pepo (Zucchini)	cgycpeB0243
Cucsa.108540	Bottle gourd (USVL1VR-Ls)	cgylsiB144
Cucsa.108540	Melon (DHL92) v3.6.1	cgymedB144
Cucsa.108540	Silver-seed gourd	carcgyB0216
Cucsa.108540	Silver-seed gourd	carcgyB0856