CsGy4G018780 (gene) Cucumber (Gy14) v2 | Cucurbit Genomics Database (CuGenDB)

Overview


Name	CsGy4G018780
Type	gene
Organism	Cucumis sativus (Cucumber (Gy14) v2)
Description	Cysteine proteinase inhibitor
Location	Chr4 : 24647459 .. 24649380 (+)

Genome Viewer

Gene Expression

Sequences

The following sequences are available for this feature:

Gene sequence (with intron)

Legend: exonCDS

Hold the cursor over a type above to highlight its positions in the sequence below.

ATGAGTATTGAAGAGTCACGTCATCGTTTGAAACCTATTATAGATATAAATGATCCCCATGTGCAAGCACTAGGGGAGTTAGCGGTGGAAAACCTTTACTCCAAGAACTCTGGGGAGAAATTGAAGTTTGTGCGTGTGGTGAATGGTTTGAAGAGTGACAAATACATTGGGCCTGGGTTTACTGAAGTAATATTATATCACCTTGTGCTGGAAGCTAAAACTAATGAAGAAATCAATTGGACATATGCCACCAAATTGGAAGAGGTATCAGGCGGCCTAATAAGGCATGTATTCCTATCTTTTGAACCTGTTCTCCCATACTACAAGCCATAATATTGGCATCATCTCTCTACTTCGGAACAAGCTTAAATAAGTTGTACCCTTTACCACCTTTGTCTAACAAAAATGGTAGCATGATATAAATAAAATAGTACTGAGATGTTACTGTCATCGATATTGAGTGTTTTGGATCCAAGTTGTTATATTAAACTCATTTTCTTCCGTCAATTTTCAATCTGACACCGACGTCTTTTTCTACTTTTTTTGCGGTTCACGAATCTCAATTCCGTTCTGCTTTCCCTTCGTCATGTATTTCAACACACTCCTCTGGTTTACAATAATTTAATTCTGATTACACATGTCAATTCTTCAAACGCTTATTGTTCTTTGTGCCTTCATGATGGTTCTTTTCTTTTTCTGCATTCTATTATAAACATTATGTCTATACAAACATGTATACTCATATCACAAAATAAAACATGTATATTAACATCACAAAATACATGATTGTAATAAACTCGTTTACTGACAGCATATATAACACCCTGAATATTTATGTATGAACACAATATGGGCCATTCATTTTTGTAGTATACATGTACAAGTACAAACACTAGCTATATTTATTTAAAAGTTAAACATCCCTAAGGAATAAATTAATATCCAACGGCACGTCTTCATTCAAGTTAATATTAGGGCACATCTTATATGTCTTGTAAACTAGGTTTAAAAATTAAGATTCATATCATAGACCTATTTACTTTTGTAAAAATGACAAAAGAACGAATCCAACCCACTTGATACACCTAATATATTGTTATACAGTTGAACATGTAACAACTCAATTTCTTATATACTAAGCTAAGGTCAATACTAATGAAATGAAAAAGAGGAAGCCAAATTCTTAAATAAAGAATTTCAAATACTCGTTTATAATTCATAATTTGAAAAAATAGAAAAAAATACTAGAAAATTCCTCCCAAGTATTGTATTTGTTGATTATCAAATAATTAACTTAATTTTTTAAAAATATTTAGTAAAAAATGGATGGCAAACATAGAGAGTTTATGGTTTTAATTAAATCTTATAGGCTAAAGTCTTAAAAATGCCAAAATGGTTATCACAGGAGCATGAAATAACAAGAATTAAAATGAAAATTTGATGTTGAGTTATATATTACTAGCCACACAAAAAACATTGTTTGATTGATATATAGTAGTACAGTGATGTTGTCTCCAAACAAATGAATTGTTTAGTCCATAGGGATGCCCTATTAGCCCTTGTTTTAATTAAGGACGTCCTTCCTCATATTAGATTCGGAGTTATCAATATCTAAAGTTCAACATCGACTATAAATACCAAGCATCTCAATATTATAGAGCATAAATCATCCTTAGAAAGTTTCTTCCAAGTACAAATTAAAAAAGCCATTAAAAATGTCGTTCACATCCCCTTTTGAACCGATTAAGGATATCAATGATCCGCAAGTGCAAGAAATAGGAAACTTAACAGTGGATGACCATAACAAGAAAACAGGTGAAAATCTGAAGTTCGTGCGTGTGGTGAATGGTTTATTTGCAAGATTTGTTGACCCATTTTCTCCTCTTGGAGGGACAGTATATGAGCTTGTGTTGGACATATAA

mRNA sequence

ATGAGTATTGAAGAGTCACGTCATCGTTTGAAACCTATTATAGATATAAATGATCCCCATGTGCAAGCACTAGGGGAGTTAGCGGTGGAAAACCTTTACTCCAAGAACTCTGGGGAGAAATTGAAGTTTGTGCGTGTGGTGAATGGTTTGAAGAGTGACAAATACATTGGGCCTGGGTTTACTGAAGTAATATTATATCACCTTGTGCTGGAAGCTAAAACTAATGAAGAAATCAATTGGACATATGCCACCAAATTGGAAGAGGATATCAATGATCCGCAAGTGCAAGAAATAGGAAACTTAACAGTGGATGACCATAACAAGAAAACAGGTGAAAATCTGAAGTTCGTGCGTGTGGTGAATGGTTTATTTGCAAGATTTGTTGACCCATTTTCTCCTCTTGGAGGGACAGTATATGAGCTTGTGTTGGACATATAA

Coding sequence (CDS)

ATGAGTATTGAAGAGTCACGTCATCGTTTGAAACCTATTATAGATATAAATGATCCCCATGTGCAAGCACTAGGGGAGTTAGCGGTGGAAAACCTTTACTCCAAGAACTCTGGGGAGAAATTGAAGTTTGTGCGTGTGGTGAATGGTTTGAAGAGTGACAAATACATTGGGCCTGGGTTTACTGAAGTAATATTATATCACCTTGTGCTGGAAGCTAAAACTAATGAAGAAATCAATTGGACATATGCCACCAAATTGGAAGAGGATATCAATGATCCGCAAGTGCAAGAAATAGGAAACTTAACAGTGGATGACCATAACAAGAAAACAGGTGAAAATCTGAAGTTCGTGCGTGTGGTGAATGGTTTATTTGCAAGATTTGTTGACCCATTTTCTCCTCTTGGAGGGACAGTATATGAGCTTGTGTTGGACATATAA

Protein sequence

MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGFTEVILYHLVLEAKTNEEINWTYATKLEEDINDPQVQEIGNLTVDDHNKKTGENLKFVRVVNGLFARFVDPFSPLGGTVYELVLDI

Homology

[Close]

BLAST of CsGy4G018780 vs. NCBI nr
Match: KGN54823.1 (hypothetical protein Csa_4G508510 [Cucumis sativus])

HSP 1 Score: 179.9 bits (455), Expect = 6.3e-42
Identity = 88/88 (100.00%), Postives = 88/88 (100.00%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60
          MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF
Sbjct: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60

Query: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 89
          TEVILYHLVLEAKTNEEINWTYATKLEE
Sbjct: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 88

[Close]

BLAST of CsGy4G018780 vs. NCBI nr
Match: KGN54824.1 (hypothetical protein Csa_4G508520 [Cucumis sativus])

HSP 1 Score: 157.1 bits (396), Expect = 4.4e-35
Identity = 77/88 (87.50%), Postives = 81/88 (92.05%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60
          MSIEE  HRLKPIIDINDPHVQ +G+LAVE+  S N GEKLKFVRVVNGLKSDKYIGPGF
Sbjct: 1  MSIEEIHHRLKPIIDINDPHVQIIGKLAVEDHDSHNPGEKLKFVRVVNGLKSDKYIGPGF 60

Query: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 89
          TEVILYHLVLEAKTNEEINWTYATKLE+
Sbjct: 61 TEVILYHLVLEAKTNEEINWTYATKLEK 88

[Close]

BLAST of CsGy4G018780 vs. NCBI nr
Match: XP_008442277.1 (PREDICTED: cysteine proteinase inhibitor A-like [Cucumis melo])

HSP 1 Score: 94.7 bits (234), Expect = 2.7e-16
Identity = 48/63 (76.19%), Postives = 53/63 (84.13%), Query Frame = 0


Query: 83  ATKLEEDINDP-QVQEIGNLTVDDHNKKTGENLKFVRVVNGLFARFVDPFSPLGGTVYEL 142
           A K  EDIND  +VQ++GNLTVDDHNKKTGENLKFVRVVNGL A F DP SPLGG +YEL
Sbjct: 6   AFKPIEDINDNLEVQDLGNLTVDDHNKKTGENLKFVRVVNGLAASFSDPISPLGGVLYEL 65

Query: 143 VLD 145
           VL+
Sbjct: 66  VLE 68

[Close]

BLAST of CsGy4G018780 vs. NCBI nr
Match: KGN54821.1 (Proteinase inhibitor I25, cystatin [Cucumis sativus])

HSP 1 Score: 88.2 bits (217), Expect = 2.5e-14
Identity = 51/91 (56.04%), Postives = 67/91 (73.63%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDP-HVQA-LGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGP 60
          MS+EE+ H  KPI DIND   VQ+ +G+LAVE+ ++K +G+ L+ V VVNGL+S  ++ P
Sbjct: 10 MSVEEAYHTSKPIEDINDDLQVQSIIGQLAVED-HNKKTGDNLELVDVVNGLRSGIFVQP 69

Query: 61 GFT-EVILYHLVLEAKTNEEINWTYATKLEE 89
          G T E ILYHL++EAKT E INWTY  KL E
Sbjct: 70 GSTHEGILYHLLVEAKTIEGINWTYVAKLLE 99

[Close]

BLAST of CsGy4G018780 vs. NCBI nr
Match: KGN51193.1 (hypothetical protein Csa_5G487700 [Cucumis sativus])

HSP 1 Score: 54.3 bits (129), Expect = 4.0e-04
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 0


Query: 12 PIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGFTEVILYHLVLE 71
          PI D++   +Q +G +AV      ++GE L+FV+V+NGL+  +    GF   I+Y LVL 
Sbjct: 22 PIKDVDSEEIQGIGGMAVRMHNETSTGENLEFVKVINGLEKGR---RGFQ--IVYTLVLS 81

Query: 72 AKTNEEINWTYATKL 87
          AK +  I WTY  K+
Sbjct: 82 AKNSLGIVWTYKAKV 91

[Close]

BLAST of CsGy4G018780 vs. TrEMBL
Match: tr|A0A0A0KZ98|A0A0A0KZ98_CUCSA (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_4G508510 PE=4 SV=1)

HSP 1 Score: 179.9 bits (455), Expect = 4.2e-42
Identity = 88/88 (100.00%), Postives = 88/88 (100.00%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60
          MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF
Sbjct: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60

Query: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 89
          TEVILYHLVLEAKTNEEINWTYATKLEE
Sbjct: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 88

[Close]

BLAST of CsGy4G018780 vs. TrEMBL
Match: tr|A0A0A0L191|A0A0A0L191_CUCSA (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_4G508520 PE=4 SV=1)

HSP 1 Score: 157.1 bits (396), Expect = 2.9e-35
Identity = 77/88 (87.50%), Postives = 81/88 (92.05%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGF 60
          MSIEE  HRLKPIIDINDPHVQ +G+LAVE+  S N GEKLKFVRVVNGLKSDKYIGPGF
Sbjct: 1  MSIEEIHHRLKPIIDINDPHVQIIGKLAVEDHDSHNPGEKLKFVRVVNGLKSDKYIGPGF 60

Query: 61 TEVILYHLVLEAKTNEEINWTYATKLEE 89
          TEVILYHLVLEAKTNEEINWTYATKLE+
Sbjct: 61 TEVILYHLVLEAKTNEEINWTYATKLEK 88

[Close]

BLAST of CsGy4G018780 vs. TrEMBL
Match: tr|A0A1S3B5B9|A0A1S3B5B9_CUCME (Cysteine proteinase inhibitor OS=Cucumis melo OX=3656 GN=LOC103486185 PE=3 SV=1)

HSP 1 Score: 94.7 bits (234), Expect = 1.8e-16
Identity = 48/63 (76.19%), Postives = 53/63 (84.13%), Query Frame = 0


Query: 83  ATKLEEDINDP-QVQEIGNLTVDDHNKKTGENLKFVRVVNGLFARFVDPFSPLGGTVYEL 142
           A K  EDIND  +VQ++GNLTVDDHNKKTGENLKFVRVVNGL A F DP SPLGG +YEL
Sbjct: 6   AFKPIEDINDNLEVQDLGNLTVDDHNKKTGENLKFVRVVNGLAASFSDPISPLGGVLYEL 65

Query: 143 VLD 145
           VL+
Sbjct: 66  VLE 68

[Close]

BLAST of CsGy4G018780 vs. TrEMBL
Match: tr|A0A0A0L3W1|A0A0A0L3W1_CUCSA (Proteinase inhibitor I25, cystatin OS=Cucumis sativus OX=3659 GN=Csa_4G508490 PE=4 SV=1)

HSP 1 Score: 88.2 bits (217), Expect = 1.7e-14
Identity = 51/91 (56.04%), Postives = 67/91 (73.63%), Query Frame = 0


Query: 1  MSIEESRHRLKPIIDINDP-HVQA-LGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGP 60
          MS+EE+ H  KPI DIND   VQ+ +G+LAVE+ ++K +G+ L+ V VVNGL+S  ++ P
Sbjct: 10 MSVEEAYHTSKPIEDINDDLQVQSIIGQLAVED-HNKKTGDNLELVDVVNGLRSGIFVQP 69

Query: 61 GFT-EVILYHLVLEAKTNEEINWTYATKLEE 89
          G T E ILYHL++EAKT E INWTY  KL E
Sbjct: 70 GSTHEGILYHLLVEAKTIEGINWTYVAKLLE 99

[Close]

BLAST of CsGy4G018780 vs. TrEMBL
Match: tr|A0A0A0KNL2|A0A0A0KNL2_CUCSA (Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_5G487700 PE=4 SV=1)

HSP 1 Score: 54.3 bits (129), Expect = 2.7e-04
Identity = 30/75 (40.00%), Postives = 45/75 (60.00%), Query Frame = 0


Query: 12 PIIDINDPHVQALGELAVENLYSKNSGEKLKFVRVVNGLKSDKYIGPGFTEVILYHLVLE 71
          PI D++   +Q +G +AV      ++GE L+FV+V+NGL+  +    GF   I+Y LVL 
Sbjct: 22 PIKDVDSEEIQGIGGMAVRMHNETSTGENLEFVKVINGLEKGR---RGFQ--IVYTLVLS 81

Query: 72 AKTNEEINWTYATKL 87
          AK +  I WTY  K+
Sbjct: 82 AKNSLGIVWTYKAKV 91

The following BLAST results are available for this feature:

BLAST of CsGy4G018780 vs. NCBI nr


Match Name	E-value	Identity	Description
KGN54823.1	6.3e-42	100.00	hypothetical protein Csa_4G508510 [Cucumis sativus]	[more]
KGN54824.1	4.4e-35	87.50	hypothetical protein Csa_4G508520 [Cucumis sativus]	[more]
XP_008442277.1	2.7e-16	76.19	PREDICTED: cysteine proteinase inhibitor A-like [Cucumis melo]	[more]
KGN54821.1	2.5e-14	56.04	Proteinase inhibitor I25, cystatin [Cucumis sativus]	[more]
KGN51193.1	4.0e-04	40.00	hypothetical protein Csa_5G487700 [Cucumis sativus]	[more]

BLAST of CsGy4G018780 vs. TAIR10


Match Name	E-value	Identity	Description

BLAST of CsGy4G018780 vs. Swiss-Prot


Match Name	E-value	Identity	Description

BLAST of CsGy4G018780 vs. TrEMBL


Match Name	E-value	Identity	Description
tr\|A0A0A0KZ98\|A0A0A0KZ98_CUCSA	4.2e-42	100.00	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_4G508510 PE=4 SV=1	[more]
tr\|A0A0A0L191\|A0A0A0L191_CUCSA	2.9e-35	87.50	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_4G508520 PE=4 SV=1	[more]
tr\|A0A1S3B5B9\|A0A1S3B5B9_CUCME	1.8e-16	76.19	Cysteine proteinase inhibitor OS=Cucumis melo OX=3656 GN=LOC103486185 PE=3 SV=1	[more]
tr\|A0A0A0L3W1\|A0A0A0L3W1_CUCSA	1.7e-14	56.04	Proteinase inhibitor I25, cystatin OS=Cucumis sativus OX=3659 GN=Csa_4G508490 PE...	[more]
tr\|A0A0A0KNL2\|A0A0A0KNL2_CUCSA	2.7e-04	40.00	Uncharacterized protein OS=Cucumis sativus OX=3659 GN=Csa_5G487700 PE=4 SV=1	[more]

Annotated Terms

The following terms have been associated with this gene:

Vocabulary: **Molecular Function**
Term	Definition
GO:0004869	cysteine-type endopeptidase inhibitor activity

Vocabulary: **INTERPRO**
Term	Definition
IPR027214	Cystatin
IPR000010	Cystatin_dom

GO Annotation

GO Assignments

This gene is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0010951	negative regulation of endopeptidase activity
cellular_component	GO:0005575	cellular_component
molecular_function	GO:0004869	cysteine-type endopeptidase inhibitor activity

Relationships

The following mRNA feature(s) are a part of this gene:


Feature Name	Unique Name	Type
CsGy4G018780.1	CsGy4G018780.1	mRNA

InterPro

Analysis Name: InterPro Annotations of cucumber Gy14 genome (v2)
Date Performed: 2018-09-25


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.10.450.10		coord: 9..84 e-value: 2.3E-9 score: 39.1 coord: 85..145 e-value: 7.5E-10 score: 40.6
None	No IPR available	PANTHER	PTHR11413:SF65	CYSTEINE PROTEINASE INHIBITOR 5	coord: 89..144 coord: 9..87
None	No IPR available	SUPERFAMILY	SSF54403	Cystatin/monellin	coord: 17..86
None	No IPR available	SUPERFAMILY	SSF54403	Cystatin/monellin	coord: 91..144
IPR000010	Cystatin domain	PFAM	PF16845	SQAPI	coord: 88..123 e-value: 3.3E-8 score: 33.7
IPR027214	Cystatin	PANTHER	PTHR11413	CYSTATIN FAMILY MEMBER	coord: 89..144
IPR027214	Cystatin	PANTHER	PTHR11413	CYSTATIN FAMILY MEMBER	coord: 9..87

Synteny

The following gene(s) are orthologous to this gene:

None

The following gene(s) are paralogous to this gene:

None

The following block(s) are covering this gene:


Gene	Organism	Block
CsGy4G018780	Cucurbita maxima (Rimu)	cgybcmaB530
CsGy4G018780	Cucurbita maxima (Rimu)	cgybcmaB564
CsGy4G018780	Cucurbita maxima (Rimu)	cgybcmaB570
CsGy4G018780	Cucurbita moschata (Rifu)	cgybcmoB504
CsGy4G018780	Cucurbita moschata (Rifu)	cgybcmoB539
CsGy4G018780	Cucurbita moschata (Rifu)	cgybcmoB544
CsGy4G018780	Cucurbita pepo (Zucchini)	cgybcpeB465
CsGy4G018780	Cucurbita pepo (Zucchini)	cgybcpeB525
CsGy4G018780	Cucumber (Chinese Long) v2	cgybcuB173
CsGy4G018780	Bottle gourd (USVL1VR-Ls)	cgyblsiB238
CsGy4G018780	Melon (DHL92) v3.5.1	cgybmeB285
CsGy4G018780	Melon (DHL92) v3.6.1	cgybmedB285
CsGy4G018780	Watermelon (Charleston Gray)	cgybwcgB283
CsGy4G018780	Watermelon (97103) v1	cgybwmB316
CsGy4G018780	Wild cucumber (PI 183967)	cgybcpiB170
CsGy4G018780	Silver-seed gourd	carcgybB0482
CsGy4G018780	Silver-seed gourd	carcgybB0521
CsGy4G018780	Cucumber (Chinese Long) v3	cgybcucB171
CsGy4G018780	Watermelon (97103) v2	cgybwmbB283
CsGy4G018780	Watermelon (97103) v2	cgybwmbB288
CsGy4G018780	Wax gourd	cgybwgoB375